America is awash in secrets and conspiracies. Moviegoers are agog over the 2,000-year-old conspiracy theory in "The Da Vinci Code," which suggests that Jesus may not have died celibate. In a conspiracy exactly one order of magnitude smaller, Brad Meltzer's new novel, "The Book of Fate," tells about...

Melissa Hunfalvay feels Claudio Reyna's pain. Not the pain caused by the sprain in Reyna's knee -- an injury the captain of the defeated U.S. World Cup soccer team sustained last week while conceding a goal in an all-important match against Ghana.

Jan Molinell lost $300,000 when Enron collapsed. A former Enron Corp. employee in Florida, Molinell closely followed the trials of Kenneth L. Lay and other Enron executives -- half-fearing that Lay's political ties to the White House would allow him to escape scot-free, and half-wondering whether an...

You could be forgiven for thinking the television images in the experiment were from 2006. They were really from 1982: Israeli forces were clashing with Arab militants in Lebanon. The world was watching, charges were flying, and the air was thick with grievance, hurt and outrage.

Antiwar liberals last week got to savor the four most satisfying words in the English language: "I told you so."

When the Rev. Martin Luther King Jr. called on America to open the doors of opportunity to people of color, the civil rights leader was making a moral argument.

The 58 fans sitting before the big-screen television were watching the Super Bowl. Psychologist Emily Pronin was watching the fans.

Accountability is in the air in Washington. At one end of Pennsylvania Avenue, Paul Wolfowitz is struggling to save his job as president of the World Bank after getting caught arranging a sweetheart deal for his, well, sweetheart. A few blocks down the road, President Bush faces endless questions...

Long before word recently broke that white referees in the National Basketball Association were calling fouls at a higher rate on black athletes than on white athletes, and long before studies found racial disparities in how black and white applicants get called for job interviews, researchers no...

In the courts and in Congress, Sen. Larry Craig is fighting to withdraw his guilty plea to a misdemeanor charge that may suggest he tried to solicit sex from a man in June at a Minneapolis airport bathroom. Rather than resign yesterday, as the senator had promised and Republicans had hoped, Craig...

If you were Barack Obama, you would be scratching your head, too.

Scrooge crept towards it, trembling as he went; and following the finger, read upon the stone of the neglected grave his own name, Ebenezer Scrooge . . . "Spirit!" he cried, tight clutching at its robe, "hear me! I am not the man I was. I will not be the man I must have been . . . "

Mitt Romney wants to round up 12 million illegal immigrants and deport them. John Edwards wants to put an end to lobbyists. All the Democratic and Republican presidential candidates rail against the ways of Washington.

Put yourself in the shoes of Sen. Barack Obama or Sen. Hillary Rodham Clinton. You are widely seen by Democratic voters as a transformational presidential candidate. Democrats are nearly evenly divided between you and your competitor, and you think you are the best candidate for your party -- and...

Three horrors await Americans who get behind the wheel of a car for a family road trip this summer: the spiraling price of gas, the usual choruses of "are-we-there-yet?" -- and the road rage of fellow drivers.

Among psychologists who study sports, there is a code word for parents who lose their temper standing on the sidelines of their children's soccer, baseball and football games: THOSE parents -- Tempestuous, Harried, Overwrought, Self-absorbed and Emotional.

Nearly a century ago, American middle-distance runner Abel Kiviat entered the Stockholm Olympics as the odds-on favorite to win the 1,500-meter race, an event in which he held the world record. Kiviat had the lead 1,492 meters into the race but was passed in the final eight meters by Britain's...

In the days after the attacks of Sept. 11, 2001, with the twin towers vanished from Manhattan's skyline, a poem by W.H. Auden could have been the song of a wounded nation. "September 1, 1939," written on the eve of World War II, seemed eerily prescient:

Have you seen the photo of Republican vice presidential nominee Sarah Palin brandishing a rifle while wearing a U.S. flag bikini? Have you read the e-mail saying Democratic presidential nominee Barack Obama was sworn into the U.S. Senate with his hand placed on the Koran? Both are fabricated -- and...

President Obama appears serenely confident as he goes about fixing the worst global financial crisis in more than half a century while simultaneously revamping the national health-care system, changing the way Americans use and produce energy, giving tax breaks to 95 percent of all households, an...

There is so much that is peculiar, irregular, silly, or downright twisted in mathematical verbiage that, certainly, we could all benefit from some soul-searching on the language of our culture. Some of mathematics usage is confusing (e. g. overuse of … Continue reading →

Recently, Abigail Thompson, a Vice President of the AMS and Professor at UC Davis, wrote a short opinion piece coming out against the use of diversity statements in hiring. As I read her piece, I found myself troubled by some … Continue reading →

As European policymakers and publics continue to grapple with the migration crisis, this conversation offers an opportunity to reflect on the role and responsibility of experts in these politically sensitive debates.

The EU-Turkey deal has been credited with helping to end the migration crisis of 2015-16, and after two years in force it has fostered a myth that such deals are cure-alls. They are not, as this MPI Europe commentary explores. Recent EU responses place great emphasis on transit routes to Europe. But what if the next major event is a different kind of shock altogether?

Fostering the social and economic inclusion of refugees has long been the domain of governments and NGOs. In the wake of the 2015–16 European migration and refugee crisis, however, new actors have emerged and taken on important roles in integrating newcomers. This report describes key discussions and takeaways from an MPI Europe conference on these developments.

As maritime arrivals climbed in 2015, EU policymakers struggled to mount a coordinated response. A range of ad hoc crisis-response tools emerged, but many officials worry that if another migration emergency were to hit Europe, the European Union may still be unprepared. This report traces the evolution of the EU response to the 2015–16 crisis and lays out recommendations to lock in progress and shore up weaknesses.

European countries have ramped up their investments in helping refugees find work and integrate into society. Yet little hard evidence exists of what programs and policies work best. This report proposes a new framework for thinking smartly about integration programming, using cost-benefit analysis to look beyond short-term, economic outcomes to also measure indirect benefits through a social-value concept.

EU policy debates about moving asylum seekers from overburdened frontline countries, such as Greece and Italy, to other Member States rarely consider how migrants form and act on preferences for certain destinations—and how difficult it may be to change these views. This issue brief explores decision-making among migrants in Greece, including how living conditions, jobs, and legal status factor in.

Refugees encounter a range of challenges after resettlement—from adjusting to a new culture and language, to finding a job. Many resettlement countries invest in predeparture orientation to help refugees develop the knowledge, skills, and attitudes to face these challenges. This report explores the many forms these programs take, highlighting important design questions and key elements that effective programs share.

As European asylum systems are tested again by the COVID-19 pandemic, which has injected the need for social distancing during processing and in reception centers, it appears lessons learned during the 2015-16 migration and refugee crisis may be fading. Chief among them: A number of Member States have phased out their buffer capacity. This MPI Europe commentary explores the diametrically different approaches taken to asylum during the pandemic.

One of the major challenges Canada faced during its extraordinary push to resettle 25,000 Syrian refugees during a four-month period was to find housing for these newcomers. This report explores how the government, resettlement case workers, and private citizens tackled this challenge—balancing cost and location, access to services, and more—and how lessons learned can improve refugee housing practices for other countries going forward.

Seasonal worker programs in the European Union have a long history, but have yet to find the sweet spot of working for migrants, employers, and countries of destination and origin alike. This policy brief explores some of the challenges common to these programs—drawing on examples in Europe, Australia, and New Zealand—and highlights promising practices.

Brussels is searching for bright ideas on how to fix the Common European Asylum System. While recent EU-level legal reforms have stalled, this report examines the many innovative, operations-focused approaches Member States have used since the 2015-16 migration crisis to improve registration and reception systems, asylum case processing, and options for returning failed asylum seekers.

The U.S. government has made important progress in shoring up weaknesses at the nexus of immigration and national security since September 11, 2001. But as new threats emerge and evolve—including public-health emergencies such as the COVID-19 pandemic—the question is whether the post-9/11 system is up to the task of meeting these challenges, as this report explores.

During this webinar, speakers discuss a MPI policy brief that explores the intersection of trauma and early childhood development, exploring how migration-related trauma and stressors can influence the wellbeing of young children of immigrants, and points to key opportunities for states to support, through early childhood and other programs.

Nearly 2 million college-educated immigrants in the United States, more than half coming with academic and professional credentials, are unable to fully utilize their professional skills and instead are stuck in low-skilled work or are unemployed. This report explores a range of programs and policies that are providing cutting-edge career navigation, relicensing, gap filling, and job search assistance to remedy this brain waste.

Nearly half of immigrant adults arriving in the U.S. since 2011 have a college degree—a far higher share than a quarter-century ago, when just 27 percent did. This striking but little noted shift in the composition of recent immigrant flows, driven in part by rising migration from Asia, comes as some policymakers press for a "merit-based" immigration system. This fact sheet examines rising human capital at U.S. and state levels.

A recent MPI study reveals that 48 percent of recent immigrants to the United States were college graduates, a sharp increase over earlier periods. How can the United States better leverage this brain gain? This commentary outlines some policies that could allow the United States to more fully utilize the professional and academic credentials that highly skilled immigrants have, for their benefit and that of the U.S. economy.

By winding down DACA over six months, President Trump may have addressed a short-term political dilemma. But this action ensures debate will rage on in search of a lasting solution, as many in Congress and beyond recognize the loss of work authorization and deportation relief will affect not only DACA recipients and their families, but also employers, universities, and communities alike, as this commentary explores.

Over the last several years it has become clear that higher order assemblies on membranes, exemplified by signalosomes, are a paradigm for the regulation of many membrane signaling processes. We have recently combined two-color direct stochastic optical reconstruction microscopy (dSTORM) with the (Clus-DoC) algorithm that combines cluster detection and colocalization analysis to observe the organization of 5-lipoxygenase (5-LO) and 5-lipoxygenase–activating protein (FLAP) into higher order assemblies on the nuclear envelope of mast cells; these assemblies were linked to leukotriene (LT) C4 production. In this study we investigated whether higher order assemblies of 5-LO and FLAP included cytosolic phospholipase A2 (cPLA2) and were linked to LTB4 production in murine neutrophils. Using two- and three-color dSTORM supported by fluorescence lifetime imaging microscopy we identified higher order assemblies containing 40 molecules (median) (IQR: 23, 87) of 5-LO, and 53 molecules (62, 156) of FLAP monomer. 98 (18, 154) molecules of cPLA2 were clustered with 5-LO, and 77 (33, 114) molecules of cPLA2 were associated with FLAP. These assemblies were tightly linked to LTB4 formation. The activation-dependent close associations of cPLA2, FLAP, and 5-LO in higher order assemblies on the nuclear envelope support a model in which arachidonic acid is generated by cPLA2 in apposition to FLAP, facilitating its transfer to 5-LO to initiate LT synthesis.

In Staphylococcus aureus–caused endocarditis, the pathogen secretes staphylocoagulase (SC), thereby activating human prothrombin (ProT) and evading immune clearance. A previous structural comparison of the SC(1–325) fragment bound to thrombin and its inactive precursor prethrombin 2 has indicated that SC activates ProT by inserting its N-terminal dipeptide Ile1-Val2 into the ProT Ile16 pocket, forming a salt bridge with ProT's Asp194, thereby stabilizing the active conformation. We hypothesized that these N-terminal SC residues modulate ProT binding and activation. Here, we generated labeled SC(1–246) as a probe for competitively defining the affinities of N-terminal SC(1–246) variants preselected by modeling. Using ProT(R155Q,R271Q,R284Q) (ProTQQQ), a variant refractory to prothrombinase- or thrombin-mediated cleavage, we observed variant affinities between ∼1 and 650 nm and activation potencies ranging from 1.8-fold that of WT SC(1–246) to complete loss of function. Substrate binding to ProTQQQ caused allosteric tightening of the affinity of most SC(1–246) variants, consistent with zymogen activation through occupation of the specificity pocket. Conservative changes at positions 1 and 2 were well-tolerated, with Val1-Val2, Ile1-Ala2, and Leu1-Val2 variants exhibiting ProTQQQ affinity and activation potency comparable with WT SC(1–246). Weaker binding variants typically had reduced activation rates, although at near-saturating ProTQQQ levels, several variants exhibited limiting rates similar to or higher than that of WT SC(1–246). The Ile16 pocket in ProTQQQ appears to favor nonpolar, nonaromatic residues at SC positions 1 and 2. Our results suggest that SC variants other than WT Ile1-Val2-Thr3 might emerge with similar ProT-activating efficiency.

In his starting section, "Path", Macfarlane admits that not all walkers are benign or appealing. While I think he is a little hard on Morris Dancers and people who walk in sandals (p. 23) he does mention that trampers can have more sinister motives than mere enjoyment of nature and movement. He mentions people who walk because they are delusional or racist.

He also discusses two writers who walked to stave off depression -  19th-century walker George Borrow and poet Edward Thomas, who was killed in World War I. Borrow, who rode around on a black Arab stallion when at home, walked over not only England but also France, Spain, Portugal, Russia, and Morocco. He knew twelve languages and was acquainted with another forty. The activity of walking exposed him to new people and allowed him to exercise his mind as he exercised his body.

Edward Thomas and his poetry had the most influence over Macfarlane. The author admits that Thomas is the guiding spirit of his book (p. 24) and his first walk in The Old Ways is one that Thomas took a hundred years earlier. Macfarlane says that while Thomas

"was drawn to the romantic figure of the self-confident solitary walker, he was more interestingly alert to how we are scattered, as well as affirmed, by the places through which we move" (p. 25).

Thomas appears throughout The Old Ways, and Macfarlane gradually tells the story of Thomas's life in the "Ghost" section of the book. Thomas suffered badly from depression and moved frequently in the hopes that his new house would help him battle it; walking was a similar way to stave it off.

Interestingly enough, American poet Robert Frost knew Thomas. The famous Frost poem, "The Road Not Taken", was inspired by a walk that Frost and Thomas took together. When Frost sent Thomas a draft of the poem, Thomas decided that it was a sign that he should enlist in the British army. He was later killed in France in 1917.

On October 29th, 2012, Hurricane Sandy hit the tri-state area. I was lucky enough to be unaffected as I live on a hill in a central portion of Queens but I had two family members who lost power for a week. I also had co-workers who live in some of the most hard-hit areas of Brooklyn and Queens. Rereading Macfarlane's "Silt" chapter after Sandy was a sobering experience as I wondered what such a walk in parts of Queens or New Jersey would involve.

In the aftermath of Sandy, I've listened to radio interviews with Dutch engineers who have advocated sea gates and houses on stilts. I've read proposals about sea walls.  In the past week, Governor Cuomo has suggested a buyout of homes in areas likely to flooded again in the future. Once the state buys the land, the homes will be demolished and the land left empty. To quote Governor Cuomo, "there are some parcels that Mother Nature owns...She may only visit once every few years...but she owns the parcel and when she comes to visit, she visits."

However, people who live in flooded and devastated areas such as Freeport, Breezy Point or the Rockaways are reluctant to say goodbye to their communities and shore-based lifestyles. Mr. Cuomo accepts that man cannot ultimately defeat nature, which is why, for example, parts of the English coast are crumbling away without the UK spending billions on sea walls or sea gates (although London is protected by the Thames Barrier). Inhabitants of New York and New Jersey seem more willing to fight nature with man-made barriers, artificially-created natural shorelines, and architectural changes such as in the Netherlands. In the end, residents of NYC will have to decide how much money they wish to spend to protect and maintain their current lifestyles and residences.

Two weeks ago, some friends and I toured Lucy Boston's house and garden. My friend Val had read Boston's books; her husband Dave hadn't heard of Boston but wanted to see the old house. We took a train from London to the nearby town of Huntington (pop 10,000), then a short taxi ride to Hemingford Grey (pop.230), a quaint small village on the River Ouse.

Here are photos of the town's main or high street:

Since we were early for our 2 PM house tour, we decided to explore the gardens. Lucy talks about designing and building the gardens in her memoir Memory in a House, which also contains some black and white photos of the gardens back when she published the book. However, I did not realize until her daughter-in-law Diana Boston gave us the tour how much of the gardens Lucy build from scratch. Apparently most of the yard was just meadow until she set to work.

What stunned me, Val, and Dave was how large the gardens were in size. We split up in the gardens, and they saw only the more cultivated side:

BRUSSELS — While the European Union has called on Member States to expand channels for foreign workers as a way to meet labour market needs and potentially tackle spontaneous migration, they have struggled to deliver on this pledge. To date, policies have focused more on attracting high-skilled workers, but less attention has been paid to admission of low- or middle-skilled nationals. Policymakers would do well not to overestimate the potential of legal channels to reduce irregular migration.

WASHINGTON – A pesar de que los gobiernos de América Latina y el Caribe han tomado medidas generosas e innovadoras para lidiar con el desplazamiento forzado desde Venezuela y más recientemente desde Nicaragua, la cálida bienvenida se ha enfriado en algunos lugares a medida que el número de entradas, la presión sobre los servicios públicos y la preocupación del público aumenta.