opposite

Dr. Amiya Rajan Barik vs State Of Odisha & Others .... Opposite ... on 13 November, 2024

1. Since the issue involved in all these three (3) Writ Petitions are identical, all were heard analogously and disposed of by the present common order.

2. For the sake of brevity, pleadings made in W.P.(C ) No.36125 of 2023 was taken as the lead case for deciding the issue in question.

3. Writ petition in W.P.(C ) No.36125 of 2023 has been filed challenging the advertisement issued by the State Selection Board (in short, "the Board") on 11.09.2023 under Annexure-1.Vide the said advertisement, the Board invited applications to fill up the post of Lecturers in various discipline including Physics in non-Government Aided Colleges of Odisha and the last date for making such application was fixed to 13.10.2023.




opposite

A Study of 3,526 Companies Shows 1 Decision Makes Startups More Successful. Most Founders Do the Opposite

Surprising new research from NYU and the Wharton School shows that entrepreneurs who start a business on their own are likelier to succeed than those who do so with one or more partners.

That's pretty much the opposite of what most aspiring founders would guess. After all, you can't be good at everything. You might be a marketing expert but not know how to manage cash flow. Or you might good at building great products but bad at setting prices for them. So you team up with someone who's strong in the areas where you're weak, and you start the business together.

This reasoning seems logical, and it is how most people--even experts--see entrepreneurship. In fact, it is such an ingrained belief that VCs and other investors routinely choose to fund companies founded by teams rather than those with a solo founder.

complete article




opposite

Opposites Together

Sts. Peter and Paul were two men from the opposite ends of Jewish society and yet each found a way to not only value each other but also challenge each other. In a Church broad enough to hold these two very different men, we are called to embrace each other and be enriched by the diversity of gifts we each possess.




opposite

What is the Opposite of Sloth?




opposite

Four Opposites Reveal Wisdom




opposite

What's the Opposite of Love?




opposite

Four Opposites Reveal Wisdom




opposite

What's the Opposite of Love?




opposite

Fear is the Opposite of Love

Dr. Albert Rossi reflects on the quote, "Fear is the opposite of love."





opposite

Christians must be 'major influencers' in American politics, say activists on opposite sides

Two Christian activists urged fellow believers to remain active in politics, contending that they have an obligation to become “major influencers” in American society by restoring civility to political discourse. 




opposite

Toni Collette to Star Opposite Colin Firth on HBO Max's Crime Drama 'The Staircase'

Based on the 2004 true-crime docuseries of the same name, the eight-episode series itself focuses on Michael Peterson, who was accused of murdering his wife Kathleen in 2001.




opposite

The HRDC domain oppositely modulates the unwinding activity of E. coli RecQ helicase on duplex DNA and G-quadruplex [Enzymology]

RecQ family helicases are highly conserved from bacteria to humans and have essential roles in maintaining genome stability. Mutations in three human RecQ helicases cause severe diseases with the main features of premature aging and cancer predisposition. Most RecQ helicases shared a conserved domain arrangement which comprises a helicase core, an RecQ C-terminal domain, and an auxiliary element helicase and RNaseD C-terminal (HRDC) domain, the functions of which are poorly understood. In this study, we systematically characterized the roles of the HRDC domain in E. coli RecQ in various DNA transactions by single-molecule FRET. We found that RecQ repetitively unwinds the 3'-partial duplex and fork DNA with a moderate processivity and periodically patrols on the ssDNA in the 5'-partial duplex by translocation. The HRDC domain significantly suppresses RecQ activities in the above transactions. In sharp contrast, the HRDC domain is essential for the deep and long-time unfolding of the G4 DNA structure by RecQ. Based on the observations that the HRDC domain dynamically switches between RecA core- and ssDNA-binding modes after RecQ association with DNA, we proposed a model to explain the modulation mechanism of the HRDC domain. Our findings not only provide new insights into the activities of RecQ on different substrates but also highlight the novel functions of the HRDC domain in DNA metabolisms.




opposite

) Laxmidhar Sethi vs State Of Odisha ..... Opposite Party on 11 November, 2024

11.11.2024 Order No.

01. 1. This matter is taken up through Hybrid Arrangement (Virtual /Physical Mode).

2. Heard learned counsel for the Petitioners and learned Addl. Standing Counsel for the State. Perused the records.

3. This is an application under Section 438, Cr.P.C. filed by the Petitioners for anticipatory bail, involving offence punishable under Sections 498-A / 323 / 342 / 506 /307 / 34 of I.P.C. read with Section 4 of D.P. Act in G.R. Case No.1305 of 2024 of the Court of learned S.D.J.M., Chatrapur arising out of Chamakhandi P.S. Case No.373 of 2024.




opposite

Asutosh Patra @ Sonu vs State Of Odisha ..... Opposite Party on 11 November, 2024

11.11.2024 Order No.

01. 1. This matter is taken up through Hybrid Arrangement (Virtual/Physical Mode).

2. Heard learned counsel for both the parties and perused the records.

3. The Petitioner is apprehending arrest for the alleged commission of offence under Sections 341/384/294/506/307/323/ 325/379 of I.P.C. in G.R. Case No.87 of 2018 of the Court of the learned J.M.F.C., Nimapara arising out of Nimapara P.S. Case No.33 of 2018.

4. It is stated by learned counsel for the Petitioner that earlier the Petitioner approached this Court by filing ABLAPL No.2915 of 2018. The said bail application was disposed of by a coordinate bench of this Court on 30.01.2019 thereby directing the Petitioner to surrender before the court below and move an application for bail with a corresponding direction to the learned court in seisin over the matter to dispose of the bail application on the very same day. Learned counsel for the Petitioner at this juncture submitted that due to communication gap with the conducting counsel, the Petitioner could not take advantage of order dated 30.01.2019.




opposite

Md. Faizuddin Khan @ vs State Of Odisha ..... Opposite Party on 12 November, 2024

12.11.2024 Order No.

01. 1. This matter is taken up through Hybrid Arrangement (Virtual/Physical Mode).

2. Heard learned counsel for both the parties and perused the records.

3. The Petitioner is apprehending arrest for the alleged commission of offence under Sections 406/ 468/471/ 420/ 120-B/34 I.P.C. read with Section 4/5 of The Prize, Chits and Money Circulation Scheme (Banning) Act in 1.C.C. No.1498 of 2013 corresponding to G.R. Case No.953 of 2014 of the Court of the learned S.D.J.M., Bhadrak arising out of Bhadrak Town P.S. Case No.78 of 2014.




opposite

Jaydevsinh Ashoksinh Jadeja vs State Of Odisha ..... Opposite Parties on 11 November, 2024

11.11.2024 Order No.

02. 1. This matter is taken up through Hybrid Arrangement (Virtual /Physical Mode).

2. Heard Senior learned counsel for the Petitioner and learned Counsel for the State as well as learned counsel for the Informant. Perused the records.

3. This is an application under Section 438, Cr.P.C. filed by the Petitioner for anticipatory bail, involving offence punishable under Sections 419, 420, 465, 467, 468, 471, 120-B, 34 of I.P.C. and Sections 66(C), 66(D) of I.T. Act in C.T. Case No.399 of 2024 of the Court of learned S.D.J.M., Bhubaneswar arising out of Cyber Crime P.S. Case No.11 of 2024.




opposite

Bijay Kumar Jena vs State Of Odisha ..... Opposite Party on 12 November, 2024

12.11.2024 Order No.

04. 1. This matter is taken up through Hybrid Arrangement (Virtual/Physical Mode).

2. Heard learned counsel for both the parties and perused the records.

3. The Petitioner is apprehending arrest for the alleged commission of offence under Sections 147/148/323/325/307/302/ 427/506/149 of I.P.C. in G.R. Case No.170 of 2017 of the Court of the learned J.M.F.C., Salipur arising out of Mahanga P.S. Case No.49 of 2017.

4. Considering the facts of the case, this Court is not inclined to grant anticipatory bail to the Petitioner. However, on the submission of the learned counsel, the Petitioner is given liberty to surrender before the learned court in seisin over the matter in the aforesaid case in the first hour within 21 working days hence and move for bail. On such event, the learned Magistrate shall consider his application for bail in the first hour strictly on the basis of the materials on record. In case of rejection of the bail application, the Petitioner may move for bail before the higher forum in the second hour. On such event, the higher forum shall consider and dispose of the bail application of the Petitioner on the same day strictly on the basis of the materials on record, by maintaining the principles of parity, if applicable.




opposite

) Pramila Rout vs State Of Odisha ..... Opposite Party on 8 November, 2024

08.11.2024 Order No.

01. 1. This matter is taken up through Hybrid mode.

2. Heard learned counsel for the Petitioners and learned Additional Standing Counsel appearing for the Opposite Party-State.

3. The present application has been filed under Section 438 of Cr.P.C. by the Petitioners seeking pre-arrest bail in connection with Mahakalpara P.S. Case No.218 of 2022, corresponding to G.R. Case No.2351 of 2022, pending in the court of learned S.D.J.M., Kendrapara, for alleged commission of offences punishable under Sections 341, 294, 307, 506, 325, 34 of I.P.C.




opposite

Bulu Jena @ Madan Jena vs State Of Odisha ..... Opposite Party on 12 November, 2024

12.11.2024 Order No.

04. 1. This matter is taken up through Hybrid Arrangement (Virtual/Physical Mode).

2. Heard learned counsel for both the parties and perused the records.

3. The Petitioner is apprehending arrest for the alleged commission of offence under Sections 147/148/323/325/307/302/ 427/506/149 of I.P.C. in G.R. Case No.170 of 2017 of the Court of the learned J.M.F.C., Salipur arising out of Mahanga P.S. Case No.49 of 2017.

4. Considering the facts of the case, this Court is not inclined to grant anticipatory bail to the Petitioner. However, on the submission of the learned counsel, the Petitioner is given liberty to surrender before the learned court in seisin over the matter in the aforesaid case in the first hour within 21 working days hence and move for bail. On such event, the learned Magistrate shall consider his application for bail in the first hour strictly on the basis of the materials on record. In case of rejection of the bail application, the Petitioner may move for bail before the higher forum in the second hour. On such event, the higher forum shall consider and dispose of the bail application of the Petitioner on the same day strictly on the basis of the materials on record, by maintaining the principles of parity, if applicable.




opposite

Dali Parida And Others vs State Of Odisha ..... Opposite Party on 8 November, 2024

08.11.2024 Order No.

01. 1. This matter is taken up through Hybrid mode.

2. Heard learned counsel for the Petitioner and learned Additional Standing Counsel appearing for the Opposite Party-State.

3. The present application has been filed under Section 48 of Cr.P.C. by the Petitioner seeking pre-arrest bail in connection with Konark P.S. Case No.118 of 2021, corresponding to G.R. Case No.506 of 2021, pending in the court of learned J.M.F.C., Konark, for alleged commission of offences punishable under Sections 341, 294, 323, 325, 506, 34 of I.P.C.




opposite

Prakash Swain vs State Of Odisha ..... Opposite Party on 8 November, 2024

08.11.2024 Order No.

01. 1. This matter is taken up through Hybrid mode.

2. Heard learned counsel for the Petitioner and learned Additional Standing Counsel appearing for the Opposite Party-State.

3. The present application has been filed under Section 438 of Cr.P.C. by the Petitioner seeking pre-arrest bail in connection with Byree P.S. Case No.95 of 2023, corresponding to C.T. Case No.946 of 2023, pending in the court of learned J.M.F.C., Chandikhole, for alleged commission of offences punishable under Sections 341, 323, 294, 307, 507, 506, 34 of I.P.C.




opposite

Kushadhwaja Jena vs State Of Odisha ..... Opposite Party on 12 November, 2024

12.11.2024 Order No.

04. 1. This matter is taken up through Hybrid Arrangement (Virtual/Physical Mode).

2. Heard learned counsel for both the parties and perused the records.

3. The Petitioner is apprehending arrest for the alleged commission of offence under Sections 147/148/323/325/307/302/ 427/506/149 of I.P.C. in G.R. Case No.170 of 2017 of the Court of the learned J.M.F.C., Salipur arising out of Mahanga P.S. Case No.49 of 2017.

4. Considering the facts of the case, this Court is not inclined to grant anticipatory bail to the Petitioner. However, on the submission of the learned counsel, the Petitioner is given liberty to surrender before the learned court in seisin over the matter in the aforesaid case in the first hour within 21 working days hence and move for bail. On such event, the learned Magistrate shall consider his application for bail in the first hour strictly on the basis of the materials on record. In case of rejection of the bail application, the Petitioner may move for bail before the higher forum in the second hour. On such event, the higher forum shall consider and dispose of the bail application of the Petitioner on the same day strictly on the basis of the materials on record, by maintaining the principles of parity, if applicable.




opposite

Saroj Kumar Swain vs State Of Odisha ..... Opposite Party on 11 November, 2024

Date of Hearing :08.11.2024 :: Date of Order :11.11.2024 A.C. Behera, J. This bail application under Section 439 of the Cr.P.C., 1973 filed by the petitioner arising out of Spl. G.R. Case No.4 of 2024 in connection with Cuttack Sadar P.S. Case No.16 of 2024 pending in the Court of learned Adhoc Addl. Sessions Judge, F.T.S.C.-II, Cuttack is taken up into consideration.

{{ 2 }}

2. I have already heard from the learned counsel for the petitioner, the learned Additional Government Advocate for the State and the learned counsel for the informant.

3. The petitioner is facing trial in the Court of learned Adhoc Addl. Sessions Judge, F.T.S.C.-II, Cuttack in Spl. G.R. Case No.4 of 2024 arising out of Cuttack Sadar P.S. Case No.16 of 2024 remaining in the jail custody since 29.01.2024 as an under trial prisoner having been charged under Section 292-A, 212, 376(2)(n) of the IPC, 1860, Section 6 of the POCSO Act, 2012 and Sections 66-E, 67-A & 67-B of the I.T. Act, 2000 along with his other co-accused persons on the allegations alleged against him that, due to the frequent talking between the petitioner and the victim since the month of May, 2022, they loved each other and the petitioner proposed the victim for marriage. Thereafter, in the months of August and November, 2023, the petitioner took the victim by his motorcycle to the OYO Hotel on three different dates and made sexual intercourse with her in a room of that hotel in each occasion and took the naked/nude photographs of the victim inside the room of that hotel through his mobile phone and sent the said nude/naked photographs to the mobile phone of the victim through whatsapp and the said nude photographs of the victim were in her mobile phone, to which, she (victim) had not disclosed before {{ 3 }} any of her family members including her parents. Thereafter, there was disturbance between the victim and the petitioner, for which, the victim stopped her talking with the petitioner. So, the petitioner made the nude photographs of the victim viral. Thereafter, on dated 07.01.2024, she (victim) lodged F.I.R. against the petitioner at Sadar police station, Cuttack, alleging the aforesaid allegations.




opposite

Darogi Yadav @ Bhupati vs The State Of Jharkhand ... ... Opposite ... on 12 November, 2024

Darogi Yadav @ Bhupati, aged about 40 years, S/o. Shri Bodhan Yadav, R/o. Vill.- Dudhania Tola, P.O.- Khaira Block, P.S.- Cherko Pathar, Dist.- Jamui, Bihar.

... ... Petitioner

-Versus -

The State of Jharkhand ... ... Opposite Party

------

CORAM: - HON'BLE MR. JUSTICE AMBUJ NATH

------

For the Petitioner : Mr. Sumit Prakash, Advocate For the State : Mr. Sudhir Kumar Mahto, A.P.P.

------

02/12.11.2024 Heard the parties.




opposite

Kaif Ansari @ Md. Kaif Ansari vs The State Of Jharkhand ... ... Opposite ... on 12 November, 2024

For the Petitioners : Mr. Vikas Kumar, Advocate For the State : Mrs. Anuradha Sahay, A.P.P.

-----

03/12.11.2024 The petitioners are apprehending their arrest for the offences punishable under Sections 341/323/325/354-B/379/452/ 504/506/34 of the Indian Penal Code.

2. Learned counsel for the petitioners submits that the petitioners have been falsely implicated in the present case and have not committed any offence as alleged in the F.I.R. As per the allegation, the petitioners tried to outrage the modesty of the informant and also snatched the gold chain from her neck worth Rs.95,000/-. It is further submitted that the petitioners are the neighbours and relatives of the informant. They have been implicated in this case by the informant due to previous enmity. The petitioners have no criminal antecedent as has been stated in paragraph no. 17 of the present application. They also undertake to co-operate in the ongoing investigation. Hence, they may be given the privilege of anticipatory bail.




opposite

Chandan Singh vs The State Of Jharkhand ... ... Opposite ... on 11 November, 2024

Chandan Singh, aged about 24 years, S/o. Kuldeep Singh, R/o. Toiladungary, P.O. & P.S.- Golmuri, Dist.- East Singhbhum, Jharkhand. ... ... Petitioner

-Versus -

The State of Jharkhand ... ... Opposite Party

------

CORAM: - HON'BLE MR. JUSTICE AMBUJ NATH

------

For the Petitioner : Mr. Zaid Imam, Advocate For the State : Mr. Tarun Kumar, A.P.P. ------ 03/11.11.2024 Heard the parties.

2. The petitioner has been made accused in connection with S.T. Case No. 231/2024 arising out of Sidhgora P.S. Case No. 13/2024 corresponding to G.R. No. 468/2024, for the offences registered under Sections 341/323/325/307/302/504/506/120(B)/34 of the I.P.C., pending in the Court of Sri B.K. Sahay, learned Additional Sessions Judge-I, Jamshedpur.




opposite

Shashi Dungdung vs The State Of Jharkhand ... ... Opposite ... on 12 November, 2024

Shashi Dungdung, aged about 24 years, S/o. Late Amrus Dungdung, R/o. Vill.- Karangagudi, Baijutoli, P.O. & P.S.- Kersai, Dist.- Simdega.

... ... Petitioner

-Versus -

The State of Jharkhand ... ... Opposite Party

------

CORAM: - HON'BLE MR. JUSTICE AMBUJ NATH

------

For the Petitioner : Mr. Gaurav, Advocate For the State : Mr. Someshwar Roy, A.P.P.

------

02/12.11.2024 Heard the parties.




opposite

Shashi Dungdung vs The State Of Jharkhand ... ... Opposite ... on 12 November, 2024

Shashi Dungdung, aged about 24 years, S/o. Late Amrus Dungdung, R/o. Vill.- Karangagudi, Baijutoli, P.O. & P.S.- Kersai, Dist.- Simdega.

... ... Petitioner

-Versus -

The State of Jharkhand ... ... Opposite Party

------

CORAM: - HON'BLE MR. JUSTICE AMBUJ NATH

------

For the Petitioner : Mr. Gaurav, Advocate For the State : Mr. Someshwar Roy, A.P.P.

------

02/12.11.2024 Heard the parties.




opposite

Chanda Dehri @ Chanda Pujhar vs The State Of Jharkhand ..... Opposite ... on 11 November, 2024

CORAM HON'BLE MR. JUSTICE RAJESH SHANKAR

-----

For the Petitioner: Mr. P. K. Roy For the State: Mr. S. P. Jha, A.P.P ----- 03/11.11.2024 Heard learned counsel for the parties.

2. The petitioner apprehending his arrest in connection with the case registered under Sections 341/323/307/504/506/34 IPC has prayed for grant of anticipatory bail.

3. Learned counsel for the petitioner submits that the petitioner has been falsely implicated in this case and has not committed any offence as alleged in the F.I.R. He along with his wife has been roped in this case by the informant due to land dispute. Even if the contents of the written report are taken to be true, the informant sustained lacerated injury on his left eyebrow and there was bleeding from his left nostril. He was advised to undergo X-Ray of skull and CTC of head, however, he did not undergo the said scanning. The injuries sustained by the informant have been found simple in nature. The said fact has been mentioned in paragraph 6 of the present anticipatory bail application. The petitioner, however, undertakes to cooperate in the ongoing investigation. Hence, he may be given the privilege of anticipatory bail.




opposite

Rajesh Yadav vs The State Of Jharkhand ... ... Opposite ... on 11 November, 2024

For the petitioner : Mr. Vijoy Kumar Roy, Advocate For the State : Mr. Shashi Kumar Verma, A.P.P

-----

02/11.11.2024 The petitioner is apprehending his arrest for the offences punishable under Sections 147/149/353/188/307/427/ 269/270 of the Indian Penal Code, Section 3 of Jharkhand Epidemic Disease (Covid-19) Act, 2020 and Section 51 of Disaster Management Act, 2005.

2. Learned counsel for the petitioner submits that the petitioner has been falsely implicated in the present case and has not committed any offence as alleged in the F.I.R. As per the allegation, the accused persons including the petitioner by forming unlawful assembly used criminal force against public servants deterring them from discharging their official duties. They also pelted stones on the government servants being part of 'Mangala' procession. It is further submitted that the petitioner was not seen as the member of 'Mangala' procession in the CCTV footage. Despite that he has been implicated in this case with malafide motive only due to the reason that he was actively involved in 'Ramnavmi' puja. Moreover, similarly situated co-accused persons namely, Rajesh Keshri and Rakesh Keshri have already been granted anticipatory bail by a Bench of this Court vide order dated 24.08.2021 passed in A.B.A No. 5644 of 2021. Hence, the petitioner may be given the privilege of anticipatory bail.




opposite

Devaki Pandey @ Devki Pandey vs The State Of Jharkhand ... ... Opposite ... on 12 November, 2024

For the Petitioners : Mr. Mahesh Tewary, Advocate For the State : Mr. Bishambhar Shastri, A.P.P.

-----

03/12.11.2024 The petitioners are apprehending their arrest for the offences punishable under Sections 147/149/341/323/307/504/506 of the Indian Penal Code.

2. Learned counsel for the petitioners submits that the petitioners have been falsely implicated in the present case and have not committed any offence as alleged in the F.I.R. As per the allegation, the petitioner nos. 2 and 3 assaulted the informant's husband due to which his left leg got fractured. So far as the petitioner no. 1 is concerned, there is no specific allegation against him. The dispute between the parties arose due to a drainage. Even if the content of the written report is taken to be true, the petitioner nos. 2 and 3 had no intention to kill the informant's husband as admittedly, he sustained fracture injury on his leg. The petitioners have no criminal antecedent as has been stated in paragraph no. 13 of the present application. They also undertake to co-operate in the ongoing investigation. Hence, they may be given the privilege of anticipatory bail.




opposite

Gudiya Kumari vs The State Of Jharkhand ... ... Opposite ... on 12 November, 2024

For the Petitioner : Mr. Subhneet Jha, Advocate For the State : Mr. Ajay Kumar Pathak, A.P.P

-----

04/12.11.2024 The petitioner is apprehending her arrest for the offences punishable under Sections 376/313/323/341/498-A/420/ 494/34 of the Indian Penal Code, Sections 3/4 of the Dowry Prohibition Act and Section 6 of the POCSO Act.

2. Learned counsel for the petitioner submits that the petitioner has been falsely implicated in the present case and has not committed any offence as alleged in the complaint leading to lodging of the present F.I.R. It has been alleged that the petitioner along with co-accused Shivnandan Sahu @ Shivandan Sahu (father- in-law) and Pramila Devi (mother-in-law) was involved in getting pregnancy of the informant terminated and that the main accused Sikandar Sahu performed another marriage with her. In fact, co- accused Sikandar Sahu has not performed any marriage with the petitioner. She is merely a co-villager and she has been implicated in this case by the informant due to personal grudge. Moreover, co- accused Shivnandan Sahu @ Shivandan Sahu, Pramila Devi and Surendra Sahu @ Sulendra Sahu have already been granted anticipatory bail by this Court vide order dated 10.09.2024 passed in A.B.A No. 3816/2024. The petitioner also undertakes to co-operate in the ongoing investigation. Hence, she may be given the privilege of anticipatory bail.




opposite

Political Habitat: An eco and opposite reaction

Will Obama’s green cabinet give birth to the next spotted owl?




opposite

Political Habitat: The opposite of earmarks

Sometimes, the big guns in Congress aim to keep stuff 'away' from their states. Senator Harry Reid and the tale of Yucca Mountain is a prime example.




opposite

What's your opposite job? This tool will tell you

If you're thinking about a career move, a fun new tool from the New York Times can offer some interesting ideas and suggestions.




opposite

Inflection Point: Do Haters Deserve Our Compassion? - Sally Kohn, author of "The Opposite of Hate"

Can you find compassion in your heart for the haters in your life?




opposite

New on Hulu in May 2020: ‘Rocketman,’ ‘The Great,’ ‘Solar Opposites,’ ‘Spaceship Earth’ and more


Here's a complete list of what's coming and going on Hulu in May.




opposite

Now streaming: ‘Star Wars’ movies, ‘The Eddy,’ ‘Bloodshot,’ ‘Solar Opposites’ and more


Looking for something to stream? Here are this week's highlights.




opposite

Watch Issa Rae Play a Gun-Wielding Stripper Opposite Danny Trejo in D Smoke’s ‘Lights On’ Visual (EXCLUSIVE)

D Smoke first wowed the music world when he won the inaugural season of "Rhythm + Flow," Netflix's hip-hop  competition show with Cardi B, Chance the Rapper and T.I. as judges. Impressing both the panel and viewers at home with meaningful, uplifting verses, the Inglewood, Calif. native, whose real name is Daniel Farris, dropped his […]





opposite

Creating a Quarantine Schedule Is Not the Opposite of Being Free-Range

At Let Grow, a wise mom named Kate Sundquist admits that while her kids were already good at playing, they certainly weren’t good at filling hours and hours of free time, playing by themselves. (Read the piece here.) So she her and boys created a schedule. “While these routines might seem restrictive or even the […]




opposite

‘Solar Opposites,’ From ‘Rick And Morty’ Co-Creator Justin Roiland, Lands On Hulu To Warm Reviews

Four aliens crash-land into suburban America. They can't agree on whether Earth is awful or awesome.

The post ‘Solar Opposites,’ From ‘Rick And Morty’ Co-Creator Justin Roiland, Lands On Hulu To Warm Reviews appeared first on Cartoon Brew.




opposite

Trump thinks the economy makes him impeachment-proof. It might be the opposite.

Any economic improvements aren’t helped by his actions.




opposite

An arrestin-1 surface opposite of its interface with photoactivated rhodopsin engages with enolase-1 [Protein Structure and Folding]

Arrestin-1 is the arrestin family member responsible for inactivation of the G protein–coupled receptor rhodopsin in photoreceptors. Arrestin-1 is also well-known to interact with additional protein partners and to affect other signaling cascades beyond phototransduction. In this study, we investigated one of these alternative arrestin-1 binding partners, the glycolysis enzyme enolase-1, to map the molecular contact sites between these two proteins and investigate how the binding of arrestin-1 affects the catalytic activity of enolase-1. Using fluorescence quench protection of strategically placed fluorophores on the arrestin-1 surface, we observed that arrestin-1 primarily engages enolase-1 along a surface that is opposite of the side of arrestin-1 that binds photoactivated rhodopsin. Using this information, we developed a molecular model of the arrestin-1–enolase-1 complex, which was validated by targeted substitutions of charge-pair interactions. Finally, we identified the likely source of arrestin's modulation of enolase-1 catalysis, showing that selective substitution of two amino acids in arrestin-1 can completely remove its effect on enolase-1 activity while still remaining bound to enolase-1. These findings open up opportunities for examining the functional effects of arrestin-1 on enolase-1 activity in photoreceptors and their surrounding cells.




opposite

An arrestin-1 surface opposite of its interface with photoactivated rhodopsin engages with enolase-1 [Protein Structure and Folding]

Arrestin-1 is the arrestin family member responsible for inactivation of the G protein–coupled receptor rhodopsin in photoreceptors. Arrestin-1 is also well-known to interact with additional protein partners and to affect other signaling cascades beyond phototransduction. In this study, we investigated one of these alternative arrestin-1 binding partners, the glycolysis enzyme enolase-1, to map the molecular contact sites between these two proteins and investigate how the binding of arrestin-1 affects the catalytic activity of enolase-1. Using fluorescence quench protection of strategically placed fluorophores on the arrestin-1 surface, we observed that arrestin-1 primarily engages enolase-1 along a surface that is opposite of the side of arrestin-1 that binds photoactivated rhodopsin. Using this information, we developed a molecular model of the arrestin-1–enolase-1 complex, which was validated by targeted substitutions of charge-pair interactions. Finally, we identified the likely source of arrestin's modulation of enolase-1 catalysis, showing that selective substitution of two amino acids in arrestin-1 can completely remove its effect on enolase-1 activity while still remaining bound to enolase-1. These findings open up opportunities for examining the functional effects of arrestin-1 on enolase-1 activity in photoreceptors and their surrounding cells.




opposite

Two Views of the Same News Find Opposite Biases

You could be forgiven for thinking the television images in the experiment were from 2006. They were really from 1982: Israeli forces were clashing with Arab militants in Lebanon. The world was watching, charges were flying, and the air was thick with grievance, hurt and outrage.




opposite

Solar Opposites

Solar Opposites (date: 5/9/2020 - Rank: 4)




opposite

Gerard Richardson: Opposites attract for weird wines

I TOOK a bottle of Cot home the other day to share with a friend and his reaction got me thinking about the subject matter for this week's column, so here’s to wines and blends you may not have come across.




opposite

Trump says coronavirus will disappear without a vaccine but Fauci says opposite

Donald Trump has been bullish about a coronavirus vaccine – so much so that experts have had to talk him off a more aggressive...




opposite

Saif Ali Khan recalls his experiences getting laid off from film opposite Kajol

Saif Ali Khan opens up about his experince getting kicked off of his debut film back in 1992