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v-ATPase Assembly Factors in Autophagy Regulation (November 14, 2024 10:00am)

Event Begins: Thursday, November 14, 2024 10:00am
Location: Off Campus Location
Organized By: Department of Molecular, Cellular, and Developmental Biology


Mentor: Daniel Klionsky
Check the MCDB Weekly update for the password.




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Biden funded new factories and infrastructure projects, but Trump might get to cut the ribbons

Trump won in large part because of voters’ frustration with high prices and a sense that the country needs major changes. But when he enters office in January, Trump will inherit an economy primed for growth.




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Two-Factor Authentication (2FA) Email Scam

What kind of email is "Two-Factor Authentication (2FA)"?

After inspecting this "Two-Factor Authentication (2FA)" email, we determined that it is spam. This fake message encourages the recipient to improve their account security to avoid service interruptions. The goal is to promote a phishing website that targets email account log-in credentials.




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The founder-CEO of Xiaomi is taking a leaf out of Elon Musk's Tesla playbook, posting a picture of himself taking a nap on the factory floor

Xiaomi CEO Lei Jun said in an X post on Tuesday that the company had produced 100,000 Xiaomi SU7 electric vehicles in 230 days. Luna Lin/AFP via Getty Images Xiaomi CEO Lei Jun posted a photo of himself sleeping on the factory floor. Lei was celebrating an EV production milestone — 100,000 units…




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The founder-CEO of Xiaomi is taking a leaf out of Elon Musk's Tesla playbook, posting a picture of himself taking a nap on the factory floor

Xiaomi CEO Lei Jun was celebrating a production milestone of 100,000 units of the SU7, his company's EV.





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Deadly Explosion Decimates Kentucky Factory, Damages Nearby Buildings

Two people were killed Tuesday when a massive explosion took place in a food dye factory in Louisville, Kentucky. Twelve people were injured in the explosion, according to WLKY. Two […]

The post Deadly Explosion Decimates Kentucky Factory, Damages Nearby Buildings appeared first on The Western Journal.




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Businesses Are Reviving This 1800s Holiday Tradition With a 'Surprise and Delight' Factor That Drives Sales — Here's How One Buzzy Brand Is Making It Work

Brands like Straightaway Cocktails are putting their own spin on a practice you might remember from childhood.




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Correction: computational design, synthesis, and assessment of 3-(4-(4-(1,3,4-oxadiazol-2-yl)-1H-imidazol-2-yl)phenyl)-1,2,4-oxadiazole derivatives as effective epidermal growth factor receptor inhibitors: a prospective strategy for anticancer therapy

RSC Med. Chem., 2024, 15,3912-3912
DOI: 10.1039/D4MD90040E, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Nilesh Raghunath Khedkar, Milind Sindkhedkar, Alex Joseph
The content of this RSS Feed (c) The Royal Society of Chemistry





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fACTOR: mentoring volunteers in Belgium

Relationships, mentoring, fun, practical work, spiritual growth and learning to love others are all part of OM Belgium's fACTOR programme.





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Project TwinTrace: Customcells works together with partners on a smart battery factory

Itzehoe/Tübingen, Germany – Setting the digital course for the future of battery cell production: Under the leadership of Customcells, the joint project TwinTrace brings together partners from industry and research to ensure particularly efficient production processes with the help of a so-called digital twin.




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The Seven Factors Lenders Use To Measure Small Business Credit

Why does qualifying for a small business loan have to be such a mystery?

According to a CB Insights study, cash flow issues are the second most common reason startups fail, accounting for 29% of failures. In many cases, access to capital would make a big difference. Yet the loan application process is notoriously opaque for small business owners. Research from the Federal Reserve Bank of New York shows the average small business owner spent 26 hours searching and applying for credit, contacted three financial institutions and submitted three credit applications. Despite this time-consuming work, only half of small-business applicants end up being approved for the loan amount they applied for.

complete article




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XP Wabi Sabi (Refactored)

All requested features delivered. Speculation avoided. Mindful of our tendency toward completeness, necessary code is added, unnecessary code is removed. Refactored.

Implementations incomplete - shadows of the their real-world counterparts, yet precisely the functions and properties required. The desire to add more, tempered by the satisfaction of not doing so.

Technique and knowledge are increased to decrease their application.

Simplicity.

I posted that on the WabiSabi page of the c2 wiki on or about October 28th, 2002.

I typically feel the same about my old writing and my old code ("what was I thinking?"), but I like this (even if it is a bit pretentious); especially the line about Technique and Knowledge. It cover many of the forces that need to balanced to ship software consistently.

Happy Friday.




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LXer: RISC-V-Based KVM Solution in PCIe Form Factor with Low/High Profile Compatibility

Published at LXer: The NanoKVM-PCIe is a recent solution from Sipeed, designed to simplify remote management of ATX PC cases and 2U servers. Built on the RISC-V architecture, it offers low power...



  • Syndicated Linux News

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Le marchand Mindfactory annonce un réapprovisionnement du processeur Ryzen 7 9800X3D à la fin du mois de décembre !

Vous rêvez d'un processeur Ryzen 7 9800X3D, malheureusement les stocks semblent inexistants et la situation ne semble pas vouloir s'arranger dans un futur proche, rien ne garantit que vous puissiez l'avoir au pied de votre sapin… En effet, aujourd'hui, on apprend que le marchand allemand Mindfactory annonce un réapprovisionnement dudit processeur à la fin du mois de décembre ! La question est alors de savoir si le dernier-né d'AMD est victime de son succès ou s'il s'agit d'un nouveau produit lancé avec des stocks inexistants. En France, la situation n'est pas meilleure, le processeur n'est pas en stock chez les marchands les plus connus et le réapprovisionnement est généralement fixé à plus de 15 jours. […]

Lire la suite




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Osteoporosis Risk Factors, Detection and Treatments

About osteoporosis and the risk factors factors, bone scans for detection and treatments for osteoporosis.




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How to Stay Fit and Healthy as a Factory or Assembly Line Worker

Staying healthy and fit in a workplace environment are key to healthy and happy employees as well as more productive ones.




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Guess Factory Store - 50% off select sale items

50% off select sale items




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Techtonica, le Satisfactory des biomes sous-terrains, a quitté son accès anticipé

Sorti depuis plus d’un an en accès anticipé, Techtonica, développé par le studio Fire Hose Games, est un jeu coopératif où vos compagnons et vous-même devrez explorer les profondeurs de la planète Calyx à l’aide d’outils variés et de machines automatisées. Le but est de récolter piller et d’exploiter de manière équitable à une échelle industrielle […]




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New MVNO Telcofactory debuts services in France under Easy by T brand

(Telecompaper) Telcofactory has started the first phase of its roll-out plan as a new MVNO in the French B2C market segment...




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Meet Chennai’s Willy Wonka in his chocolate factory as city-based Cheers Chocolates launches its first store





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What factors will dominate India’s real estate market in 2024?

The interplay of shifting consumer preferences, governmental regulations, and market dynamics will result in an active real estate market in 2024.  In recent years, there has been notable growth in the Indian real estate sector. Almost all of the records … Continue reading



  • Real Estate News
  • Factors dominating India's real estate market.
  • India's real estate
  • India's real estate market

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Five Factors That No Homebuyer Should Ignore When Selecting a Luxurious Property

Are you trying to find a cozy haven with a view of the city skyline? The desire for luxurious living is growing, and renowned builders like Nitara Projects are fostering this desire by offering strong, innovative, and tastefully designed premium … Continue reading



  • Real Estate News
  • Indian real estate
  • Indian Real Estate market
  • luxurious properties
  • Luxurious properties in India

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3 Factors to Consider Before Starting a Blog – Maintaining Blogging Momentum

The post 3 Factors to Consider Before Starting a Blog – Maintaining Blogging Momentum appeared first on ProBlogger.

Originally posted by Darren Rowse, Updated for 2024 Starting a blog is an adventure—a journey I’ve embarked on more times than I can count. And along the way, I’ve learned a thing or two about what it takes to keep that momentum going. Today, I want to share some updated ...more

The post 3 Factors to Consider Before Starting a Blog – Maintaining Blogging Momentum appeared first on ProBlogger.

     



  • Miscellaneous Blog Tips
  • Start a Blog

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Northern lights or a tomato factory?

Should have gone to....




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X Factor's Eoghan Quigg pays tribute to Liam Payne

Eoghan was a contestant on the same series Liam and recalls their time together.




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Why Mercedes put ‘a reminder of joy and pain’ on display in their factory lobby | Formula 1

Mercedes have put the car from Lewis Hamilton's controversial 2021 championship defeat on display in the lobby at their factory.




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Automatically Checking Feature Model Refactorings

A feature model (FM) defines the valid combinations of features, whose combinations correspond to a program in a Software Product Line (SPL). FMs may evolve, for instance, during refactoring activities. Developers may use a catalog of refactorings as support. However, the catalog is incomplete in principle. Additionally, it is non-trivial to propose correct refactorings. To our knowledge, no previous analysis technique for FMs is used for checking properties of general FM refactorings (a transformation that can be applied to a number of FMs) containing a representative number of features. We propose an efficient encoding of FMs in the Alloy formal specification language. Based on this encoding, we show how the Alloy Analyzer tool, which performs analysis on Alloy models, can be used to automatically check whether encoded general and specific FM refactorings are correct. Our approach can analyze general transformations automatically to a significant scale in a few seconds. In order to evaluate the analysis performance of our encoding, we evaluated in automatically generated FMs ranging from 500 to 2,000 features. Furthermore, we analyze the soundness of general transformations.




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Factors affecting the intention to continue to visit the virtual world metaverse

A metaverse is a virtual shared space connected to the real world, an alternative reality that enables economic activities, exchanges, and transactions as well as formation of relationships between user avatars and non-player characters (NPCs). Initial experiences of the metaverse were not very satisfactory; new virtual world metaverses may or may not survive as information services or platforms. The purpose of this empirical study is to identify the characteristics of a virtual world metaverse and their effects on intention to continue usage of the platform. Considering the metaverse as a new type of user experience and a powerful mode of communication, we examine the mediating role of these characteristics according to Pine and Gilmore's (1998) experience economy theory, which enriches our understanding of the factors affecting the success of a metaverse. In addition, since social interaction is important in metaverses, we extend Pine and Gilmore's experience economy model by including Schmitt's (2011) relate experience for better understanding.




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Making Mobile Learning Work: Student Perceptions and Implementation Factors

Mobile devices are the constant companions of technology users of all ages. Studies show, however, that making calls is a minimal part of our engagement with today’s smart phones and that even texting has fallen off, leaving web browsing, gaming, and social media as top uses. A cross-disciplinary group of faculty at our university came together in the mLearning Scholars group to study the potential for using mobile devices for student learning. The group met bi-weekly throughout a semester and shared thoughts, ideas, resources, and examples, while experimenting with mobile learning activities in individual classes. This paper summarizes student perceptions and adoption intent for using mobile devices for learning, and discusses implementation issues for faculty in adding mobile learning to a college course. Outcomes reflect that mobile learning adoption is not a given, and students need help in using and understanding the value in using personal devices for learning activities.




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MOOC Success Factors: Proposal of an Analysis Framework

Aim/Purpose: From an idea of lifelong-learning-for-all to a phenomenon affecting higher education, Massive Open Online Courses (MOOCs) can be the next step to a truly universal education. Indeed, MOOC enrolment rates can be astoundingly high; still, their completion rates are frequently disappointingly low. Nevertheless, as courses, the participants’ enrolment and learning within the MOOCs must be considered when assessing their success. In this paper, the authors’ aim is to reflect on what makes a MOOC successful to propose an analysis framework of MOOC success factors. Background: A literature review was conducted to identify reported MOOC success factors and to propose an analysis framework. Methodology: This literature-based framework was tested against data of a specific MOOC and refined, within a qualitative interpretivist methodology. The data were collected from the ‘As alterações climáticas nos média escolares - Clima@EduMedia’ course, which was developed by the project Clima@EduMedia and was submitted to content analysis. This MOOC aimed to support science and school media teachers in the use of media to teach climate change Contribution: By proposing a MOOC success factors framework the authors are attempting to contribute to fill in a literature gap regarding what concerns criteria to consider a specific MOOC successful. Findings: This work major finding is a literature-based and empirically-refined MOOC success factors analysis framework. Recommendations for Practitioners: The proposed framework is also a set of best practices relevant to MOOC developers, particularly when targeting teachers as potential participants. Recommendation for Researchers: This work’s relevance is also based on its contribution to increasing empirical research on MOOCs. Impact on Society: By providing a proposal of a framework on factors to make a MOOC successful, the authors hope to contribute to the quality of MOOCs. Future Research: Future work should refine further the proposed framework, by in testing it against data collected in other MOOCs.




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Key Factors for a Creative Environment in Saudi Arabian Higher Education Institutions

Aim/Purpose: This research explores the influence of organizational-level and individual-level creativity and innovation and the technology acceptance model toward the higher education creative environment that consists of research creativity and teaching creativity. Background: Creativity and innovation are essential pillars for higher education institutions (HEIs). The two terms are interconnected, where creativity is referring to finding better ideas to do the work, while innovation is referring to how to do and implement these creative ideas. Choosing the optimal creative process and the organizational support needed to develop it is an important goal in achieving a creative and inventive environment. For the success of the creative environment to ensure the improvement of higher education institutions, information technology as social networking sites plays a crucial part in the creative process within universities. However, assessing the creativity and innovation of Saudi higher education institutions has not been well recognized. Universities today serve as knowledge-based institutions because they are at the forefront of cutting-edge R&D and scientific innovations. Creating such a productive research environment in universities, however, necessitates a work culture that encourages employees to be more creative while also encouraging the creation of new ideas and innovations. Methodology: A survey instrument was utilized as a quantitative method for this research to gather data from the study sample on the influencing variables employed in the research framework. Respondent data were analyzed using a disjoint two-stage method using PLS-SEM path modelling. Contribution: The results of this research contribute to the theoretical and scientific literature by offering a model of creativity and innovation in higher education institutions. The model proposes an optimal blend of organizational, individual, and technology variables that contribute to the development of the Higher Education Creative Environment in HEIs via creativity in teaching and research and a culture of innovation. In another way, the proposed framework especially helps to comprehend the challenges regulating establishing teaching and research creativity in HEIs via the adoption of organizational, individual, and technology enablers identified as part of this study. Findings: According to the results, organizational factors such as organizational encouragement, freedom, and challenging work have a positive relationship with the higher education creative environment. However, realistic work pressure, a lack of organizational impediments, managerial encouragement, and work group support is insufficient to affect the creative environment in higher education in Saudi Arabia. Individual variables (creative thinking skills and expertise, for example) also have a positive impact on the higher education creative environment. In the higher education creative environment, however, the influence of intrinsic motivation is insignificant. Finally, technology factors such as social networking site adoption intention, perceived usefulness, and perceived ease of use have the potential to influence the higher education creative environment. Recommendations for Practitioners: On the practical front, the obvious recommendation of this research is that it enables top leadership in Saudi HEIs to rethink the norms of creativity and innovation in their institutions, thereby instilling a mindset guided by a flourishing culture of creativity in the HEI environment with a specific focus on creativity practices in research and teaching domains. Furthermore, to promote the environment’s creativity within Saudi Arabian HEIs, university leaders must consider the suggested Organizational, Individual, and Technology factors as key enablers of creativity and innovation, which will guide them in revisiting their strategic actions in terms of further augmenting the creative performance of their academic’s staff, thereby sustaining a culture of Higher Education Creative Environment (HECE). Recommendation for Researchers: This study addressed many organizational, individual, and technology variables that facilitate Saudi Arabian HECE accomplishment in the form of research and teaching creativity. Furthermore, fresh insights for Saudi public HEIs are revealed when the success aspects of the creative environment are considered. If academic leadership at Saudi HEIs is to encourage the creative environment in general and creativity in teaching and research, it would be suitable for them to highlight individual, organizational, and technology success elements. As a result, their HEIs will be able to produce more innovative research, products, and services that can support and meaningfully achieve national transformation initiatives, opening the path for a transition into a knowledge-based economy. Impact on Society: In fact, this research is based on a quantitative research method, and the findings were also significant especially considering the current global crises. It is clearly understood by this process that includes organizational, individual, and technology factors as key enablers of the creative performance of academic staff, thereby sustaining a culture of HECE. Future Research: While providing the research model, it is probable that this study overlooked any other crucial aspects influencing creativity and innovation. As a result, future research should look at additional variables that may impact HECE in Saudi Arabian HEIs. Furthermore, while this study focused on deriving HECE with a particular emphasis on research and teaching creativity as results, future research might look at deriving other creativity outcomes (e.g., entrepreneurial creativity) within the investigated HECE dimension.




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Investigating Factors Contributing to Student Disengagement and Ownership in Learning: A Case Study of Undergraduate Engineering Students

Aim/Purpose: Despite playing a critical role in shaping the future, 70% of undergraduate engineers report low levels of motivation. Student disengagement and a lack of ownership of their learning are significant challenges in higher education, specifically engineering students in the computer science department. This study investigates the various causes of these problems among first-year undergraduate engineers. Background: Student disengagement has become a significant problem, especially in higher education, leading to reduced academic performance, lower graduation rates, and less satisfaction with learning. The study intends to develop approaches that encourage a more interesting and learner-motivated educational environment. Methodology: This research uses a mixed methods approach by combining quantitative data from a survey-based questionnaire with qualitative insights from focus groups to explore intrinsic and extrinsic motivators, instructional practices, and student perceptions of relevance and application of course content. The aim of this method is to make an all-inclusive exploration into undergraduate engineering students’ perspectives on factors contributing to this disengagement and the need for more ownership. Contribution: Inculcating passion for engineering among learners seems demanding, with numerous educational programs struggling with issues such as a lack of interest by students and no personal investment in learning. Understanding the causes is of paramount importance. The study gives suggestions to help teachers or institutions create a more engaged and ownership-based learning environment for engineering students. Findings: The findings revealed a tangled web influencing monotonous teaching styles, limited opportunities and applications, and a perceived gap between theoretical knowledge and real-world engineering problems. It emphasized the need to implement more active learning strategies that could increase autonomy and a stronger sense of purpose in their learning journey. It also highlights the potential use of technology in promoting student engagement and ownership. Further research is needed to explore optimal implementation strategies for online simulations, interactive learning platforms, and gamification elements in the engineering curriculum. Recommendations for Practitioners: It highlights the complex interplay of intrinsic and extrinsic motivation factors and the need to re-look at instructional practice and emphasize faculty training to develop a more student-centered approach. It also stresses the need to look into the relevance and application of the course content. Recommendation for Researchers: More work needs to be done with a larger, more diverse sample population across multiple institutions and varied sociocultural and economic backgrounds. Impact on Society: Enhancing learners’ educational experience can result in creating a passionate and competent team of engineers who can face future obstacles fearlessly and reduce the production of half-baked graduates unprepared for the profession’s challenges. Future Research: Conduct long-term studies to assess the impact of active learning and technology use on student outcomes and career readiness. Investigate scaling up successful strategies across diverse engineering programs. See if promising practices work well everywhere.




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Connecting with the Y Generation: an Analysis of Factors Associated with the Academic Performance of Foundation IS Students




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Factors Influencing the Decision to Choose Information Technology Preparatory Studies in Secondary Schools: An Exploratory Study in Regional/Rural Australia




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Contextual Factors and Administrative Changes




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Customer Service Factors Influencing Internet Shopping in New Zealand




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Demographic Factors Affecting Freshman Students' Attitudes towards Software Piracy: An Empirical Study




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The Adoption of Single Sign-On and Multifactor Authentication in Organisations: A Critical Evaluation Using TOE Framework




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A Comparison Study of Impact Factor in Web of Science and Scopus Databases for Engineering Education and Educational Technology Journals




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Applying a Modified Technology Acceptance Model to Qualitatively Analyse the Factors Affecting E-Portfolio Implementation for Student Teachers’ in Field Experience Placements




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Critical Design Factors of Developing a High-quality Educational Website: Perspectives of Pre-service Teachers




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To Social Login or not Login? Exploring Factors Affecting the Decision




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Factors Driving Business Intelligence Culture

The field of business intelligence (BI), despite rapid technology advances, continues to feature inadequate levels of adoption. The attention of researchers is shifting towards hu-man factors of BI adoption. The wide set of human factors influencing BI adoption con-tains elements of what we call BI culture – an overarching concept covering key managerial issues that come up in BI implementation. Research sources provide different sets of features pertaining to BI culture or related concepts – decision-making culture, analytical culture and others. The goal of this paper is to perform the review of research and practical sources to examine driving forces of BI – data-driven approaches, BI agility, maturity and acceptance – to point out culture-related issues that support BI adoption and to suggest an emerging set of factors influencing BI culture.




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Factors Influencing Women’s Decision to Study Computer Science: Is It Context Dependent?

Aim/Purpose: Our research goal was to examine the factors that motivate women to enroll in Computer Science (CS) courses in order to better understand the small number of women in the field of CS. Background: This work is in line with the growing interest in better understanding the problem of the underrepresentation of women in the field of CS. Methodology: We focused on a college that differs in its high numbers of female CS students. The student population there consists mostly of religious Jews; some of them are Haredi, who, because of their unique lifestyle, are expected to be the breadwinners in their family. Following group interviews with 18 students, a questionnaire was administered to all the female students and 449 of them responded. We analyzed it statistically. We compared the responses of the Haredi and non-Haredi students. Contribution: The main contribution of this work lies in the idea that studying the factors underlying women’s presence in a CS program in unique communities and cultures, where women are equally represented in the field, might shed light on the nature of this phenomenon, especially whether it is universal or confined to the surrounding culture. Findings: There were significant differences between the Haredi and non-Haredi women regarding the importance they attributed to different factors. Haredi women resemble, regarding some social and economic variables, women in developing countries, but differ in others. The non-Haredi women are more akin to Western women, yet they did not completely overlap. Both groups value their family and career as the most important factors in their lives. These factors unify women in the West and in developing countries, though with different outcomes. In the West, it deters women from studying CS, whereas in Israel and in Malaysia, other factors can overcome this barrier. Both groups attributed low importance to the masculine image of CS, found important in the West. Hence, our findings support the hypothesis that women’s participation in the field of CS is culturally dependent. Recommendations for Practitioners: It is important to learn about the culture within which women operate in order to attract more women to CS. Recommendations for Researchers: Future work is required to examine other loci where women are underrepre-sented in CS, as well as how the insights obtained in this study can be utilized to decrease women’s underrepresentation in other loci. Impact on Society: Women's underrepresentation in CS is an important topic for both economic and social justice reasons. It raises questions regarding fairness and equality. In the CS field the gender pay gaps are smaller than in other professional areas. Thus, resolving the underrepresentation of women in CS will serve as a means to decrease the social gender gap in other areas.




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Factors Determining the Balance between Online and Face-to-Face Teaching: An Analysis using Actor-Network Theory




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Critical Success Factors for Implementing Business Intelligence Systems in Small and Medium Enterprises on the Example of Upper Silesia, Poland