A $2.9 million payout is being challenged in court today after it was found Nationwide News defamed actor Geoffrey Rush in a high-profile case earlier this year.

A Sydney mechanic who rescued a seven-year-old girl being raped by convicted sex offender Anthony Sampieri tells a court he still has nightmares about the "feeling of a scalpel being dragged across the back of my neck".

AN EXOTIC dancer claims she was abused and “drugged into near unconsciousness” for not going along with a club’s scheme. WARNING: Graphic.

Acer is joining a flurry of PC makers in adopting the next wave of NVIDIA and Intel chips inside its laptops. It's updating its 15.6-inch Predator Triton 500 (above) and Nitro 5 (below) gaming portables to use NVIDIA's new GeForce RTX Super laptop GPUs as well as Intel's 10th-generation Core H-series processors. As you might guess, the premium Predator series is the highlight. It comes with up to a GeForce RTX 2080 Super Max-Q to deliver speedier and more efficient graphics, and mates that with a 300Hz, 3ms response IPS display and per-key RGB keyboard lighting.

Lenovo is leaping quickly on the latest NVIDIA and Intel technology for its gaming laptops. It's introducing Legion 5i and Legion 7i portables (successors to the Y540 and Y740 respectively) that, most notably, are among the first to use NVIDIA's Advanced Optimus graphics switching. The tech both lowers power consumption in less-intensive moments and ramps up performance in GPU-heavy situations, theoretically giving you added battery life and higher frame rates in the same package. The Legion 7i also touts the option of new GeForce RTX 2080 Super Max-Q graphics if you insist on the best possible visuals.

Brandy drops the lead video from her first album since 2012.

BIA also dropped a quick quarantine verse to keep us going.

"It was a very special honor."

The province announced Friday it was easing restrictions on Ontario’s professional sports teams to open their doors, subject to municipal guidelines.

Scientists have challenged a key plot point of the 1993 blockbuster Jurassic Park with new research suggesting raptors hunted alone rather than in packs.

Some of the top creative minds at Mexican broadcaster Televisa are puzzling over an unexpected challenge: crafting their signature soap operas without a single love scene or even a tender kiss.

Researchers at Washington University School of Medicine in St. Louis found that gene therapy in mice helped build strength and significant muscle mass quickly, while reducing the severity of osteoarthritis. The gene therapy also prevented obesity, even when the mice were fed a high-fat diet.

Given the rapid spread of COVID-19 and its relatively high mortality, filling the gap for coronavirus-specific drugs is urgent.

When seeking the fastest pathway to a vaccine to prevent coronavirus disease 19 (COVID-19), defining the stakes and potential hurdles is critical, says Barney Graham in this Perspective.

The Duchess of Cambridge has teamed up with the National Portrait Gallery to launch the Hold Still project.

In this week's Royal Rota, our team discuss the Duchess of Cambridge's latest volunteer work and Princess Charlotte birthday celebrations.

JASON Day recorded yet another top-10 finish at a major but was left to rue what might have been after his unlikely final round US Open charge was snuffed out in a sand trap.

North Melbourne footballer Majak Daw has been committed to stand trial over the alleged rape of a teenage girl in 2007.

A multi-disciplinary team of scientists will study climate change by allowing themselves to become trapped in ice during the Arctic winter.

Fancy your home as an "hermetically sealed space ship" this winter, and keeping warm to boot? Here's how you can do both and not pump out more electricity, gas or wood smoke.

An ANU demographer is "concerned" the coronavirus pandemic will result in an accelerated reduced birthrate and a decline in future taxpayers, affecting Australia's socioeconomic future.

An easing of coronavirus restrictions means non-essential shopping has the green light from this weekend, but that doesn't mean all the stores are ready to throw open their doors immediately.

The NSW Government releases the blueprint for the promised Metro West, revealing it will acquire 154 properties to accommodate the multi-billion dollar project.

Rabbits are the millennial pet of choice, and their affection is more valuable now than ever

In this time of social isolation, mental health is top of mind. Here’s a guide to video chat, phone and even text therapy in Canada

This versatile treatment can soothe ills ranging from anxiety and phobias to pain and childbirth.

(MedPage Today) -- Triple therapy -- with methotrexate, hydroxychloroquine, and sulfasalazine -- is little used for the treatment of rheumatoid arthritis (RA) in the U.S. today, and clinical outcomes showed less efficacy than regimens combining...

Rapman moves from YouTube to feature films with "Blue Story," a tale of two South-East London friends living in different neighborhoods torn apart by gang violence.

"Blue Story," the feature filmmaking debut from Rapman, faced many obstacles on its way to reaching U.S. screens and being a U.S. hit.

Veteran Times journalist Jim Newton's graceful "Man of Tomorrow: The Relentless Life of Jerry Brown" doubles as a history of postwar California.

By: Stacy Ehrlich and Justine E. Johnson On March 18, 2020, the Food and Drug Administration (FDA) published a final rule (21 C.F.R. Part 1141) requiring textual and graphic health warnings to be included on all cigarette packages and advertisements.[1]  FDA simultaneously published two related guidance documents: (1) Required Warnings for Cigarette Packages and Advertisements,

The post FDA ISSUES FINAL RULE ON GRAPHIC WARNINGS FOR CIGARETTE PACKAGES AND ADVERTISEMENTS appeared first on Kleinfeld Kaplan & Becker LLP.

By: Daniel Dwyer and Daniel Logan On March 27, 2020, the President signed into law the Coronavirus Aid, Relief, and Economic Security Act, or “CARES” Act (Pub. Law 116-136), which includes a comprehensive revision of the rules governing over-the-counter (OTC) drugs currently marketed under monographs published by the Food and Drug Administration (FDA).  This law

The post New Opportunities for OTC Monograph Drugs under the CARES Act appeared first on Kleinfeld Kaplan & Becker LLP.

ZOLL Medical, a part of the Asahi Kasei Group, won EU clearance for its SuperSaturated Oxygen (SSO2) Therapy System to be used to minimize the damage that heart attacks cause within heart muscle. Approved about a year ago in the United States, SSO2 is the only option beyond percutaneous coronary intervention (stenting) that can help […]

Experts discuss recent cancellation of first-in-class drug

The charity's Centre for Drug Development will sponsor and fund a future Phase I clinical trial for CB213

The guideline is designed to help healthcare professionals who are not kidney specialists to prevent, detect and manage AKI in hospitalised patients with suspected or confirmed COVID-19

RBX2660 may bring an innovative therapeutic option to patients suffering from C. diff

Lyra Therapeutics, a biotech company developing a new way to treat your persistently runny nose, has raised $56 million in its public markets debut. Late Thursday, Lyra offered 3.5 million shares priced at $16 apiece, which was the high end of its projected $14 to $16 price range. Those shares are expected to begin trading […]

Chimeric antigen receptor T-cell therapies have shown remarkable efficacy in leukemia and lymphoma patients who relapsed or were refractory to several prior treatments, but many challenges remain in the cancer cell therapy field. Strategies that may improve upon first-generation therapies were presented during the American Association for Cancer Research virtual meeting with encouraging early activity, […]

PTC Therapeutics has reached an agreement to acquire Censa Pharmaceuticals and its lead asset, an experimental metabolic disorder therapy that is now being prepared for a pivotal study. The deal, announced after the market close Wednesday, will bring South Plainfield, NJ-based PTC (NASDAQ: PTCT) another compound for its pipeline of rare disease drugs. Wellesley, MA-based […]

Massachusetts-based biotech Disarm Therapeutics has hired Dr Alvin Shih as their new President and CEO.

The Cambridge, Mass.-based firm has set itself the task of creating a new class of disease-modifying therapeutics for patients with axonal degeneration, a central drive of neurological disease.

Dr Shih brings to the role a range of experiences. Having graduated with a biology degree from Vanderbilt University in 1996, Shih joined management consultancy McKinsey where he worked as a business analyst for two years.

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Dr Lisa von Moltke has left Aklermes and has joined Seres Therapeutics as its new Chief Medical Officer.

Chief Executive Officer at Seres, Eric Shaff, said Seres will benefit from von Moltke’s “extensive experience directing successful development programs, leading clinical teams, and interacting with regulatory agencies across multiple areas of medicine.”

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The pharmaceutical firm has purchased the company, which specializes in advancing treatments and diagnostics for ocular disorders.

This week, I’m rerunning some popular posts while I prepare for this Friday’s video webinar: Industry Update and COVID-19 Impact: PBMs & Payers.

I suspect this deal will remain profitable for the participating companies even as COVID-19 alters the US. prescription payer mix. Click here to see the original post and comments from January 2020. National market shares for the largest PBMs in 2019 appears as Exhibit 88 of our 2020 Economic Report on U.S. Pharmacies and Pharmacy Benefit Managers.

P.S. Sorry that today's meme is one day too late for Star Wars day.

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Just before the holidays, Cigna’s Express Scripts business announced a market-changing deal with Prime Therapeutics. Click here to read the press release.

There's been very little written about this transaction, though it has potentially major implications. Below, I share my thoughts on the following topics arising from the deal:

• Implications for manufacturers and pharmacies

• The role of the secretive Ascent Health Services

• What this all means for Walgreens

• Why the Federal Trade Commission won’t challenge the deal

A few weeks ago, I explained why integrated insurer / PBM / specialty pharmacy / provider organizations are poised to restructure U.S. drug channels. The Express Scripts / Prime deal signals that the channel will continue its amazing pace of reinvention.

The scale, scope, and interconnectedness of today’s market participants make the system increasingly resistant to massive disruption from either external players like Amazon or a government takeover. Like it or not, the channel will continue to gain power and extract profit. Read on and see if you agree.
Read more »

Originally published in February 1967

-- Read more on ScientificAmerican.com

Novartis has revealed that the European Commission has moved to approve Cosentyx (secukinumab) for the treatment of active non-radiographic axial spondyloarthritis (nr-axSpA) in adult patients.

A Phase 3 study of Sanofi and Regeneron’s Libtayo (cemiplimab) as a monotherapy for advanced or metastatic non-small cell lung cancer (NSCLC) has been stopped early after showing strong overall survival benefit, it has emerged.