pharma Japan-based pharma firm Eisai to open Australian HQ in Melbourne By www.invest.vic.gov.au Published On :: Thu, 06 Nov 2014 10:38:00 +1000 Japanese-based pharmaceutical company Eisai has announced it will open its Australian headquarters in Melbourne to provide a platform to market its portfolio of epilepsy and oncology products. The company ranks in the top 25 pharmaceutical companies in the world by revenue, and employs over 10,000 people worldwide. Full Article
pharma Global Pharma leaders Janssen collaborate with Melbourne’s Monash By www.invest.vic.gov.au Published On :: Mon, 12 Jan 2015 11:27:00 +1000 Global pharmaceutical company Janssen-Cilag, a subsidiary of Johnson & Johnson, has signed a three-year research collaboration agreement with Melbourne’s Monash University. The collaboration will focus on ground-breaking research at Monash University to develop potential new medicines to treat autoimmune diseases and disorders . Full Article
pharma 20x Lorrex Diarrhoea Relief Liquid Caps, 2mg Loperamide $3.99 Delivered @ PharmacySavings By www.ozbargain.com.au Published On :: Thu, 14 Nov 2024 19:27:23 +1100 Hi Ozbargainers, I was watching in amazement as the TravelKon sim card deal clocked over 300+ votes, great deal and also indicative of the number of Ozbargainers thinking about taking off overseas in the next 3 months, so on this note being the ambulance chaser entrepreneur that I am, I thought - what a great time for a deal on Diarrhoea relief. I reached out to a new supplier and asked for a deal so I could offer an ATL on diarrhoea relief. Nova Pharma came good and after scouring the web I think I can say, this is by FAR the best price for this item delivered anywhere in Oz - At this price, why risk taking off without a box in your hand luggage. The box says: "Lorrex acts to restore normal bowel function", and we all want that! Item: 20x Lorrex Liquicaps, Loperamide Hydrochloride 2mg Link: https://pharmacysavings.com.au/products/travel-essentials-tr… Price: $3.99 Code: Not required Exp: End July 2025 Delivery: FREE I'm going to give a special shout out to a very Shorted dated product, but I know many of you don't mind buying short dated at the right price: Item: 70x Fexit 180mg, Fexofenadine Hydrochloride Price: $4.99 Delivery: FREE Exp: End November 2024 Link: https://pharmacysavings.com.au/products/trust-fexit-180-fexo… Ozbargains Favourites have again been restocked: 100x Hayfexo @ $19.99: https://www.ozbargain.com.au/node/776153 200x Cetirizne 200x Cetirizine @ $19.99: https://www.ozbargain.com.au/node/834351 200x Lorazol, Loratadine 10mg @ $19.99 https://www.ozbargain.com.au/node/837337 (RESTOCKED) 70x Cetirizine 10mg + 70x Loratadine 10mg + 48x Ibuprofen @ $17.99 https://www.ozbargain.com.au/node/873236 70x Trust Fexit 180mg + 70x Cetrine or 70x Lorazol @ $19.99: https://www.ozbargain.com.au/node/858658 192x Trust Ibuprofen 200mg, Coated Tablets @ $10.99 now $9.99 https://www.ozbargain.com.au/node/844425 These bulk deals are still powering along as well: 140x Cetirizine + 140x Loratadine + 140x Fexofenadine https://www.ozbargain.com.au/node/866620 Full Article Health & Beauty Diarrhoea Relief Loperamide
pharma Merged pharmaceutical firms seek fast-track route to savings By www.logisticsit.com Published On :: The pharmaceutical industry is preparing for an accelerated pace of consolidation, with the number of mergers up 39 per cent since 2017¹. This year has already witnessed its first ‘super merger’ between two of the world’s largest pharmaceutical companies, Bristol-Myers and Celgene, valued at $74 billion.² Full Article
pharma Pharmacy college job fairs propel rapport between academia and industry to create capable workforce By www.pharmabiz.com Published On :: Thursday, November 14, 2024 08:00 IST Pharmacy college job fairs play a critical role in bridging the gap between academia and industry. The fair provides a platform for pharmaceutical companies to communicate their hiring needs directly to students. This Full Article
pharma Pharmacies vote to cut opening hours in funding protest By www.bbc.com Published On :: Thu, 14 Nov 2024 00:07:06 GMT Pharmacists in England, Wales and Northern Ireland to reduce opening hours and stop home deliveries. Full Article
pharma Won’t back off from ‘Pharma Village’, says Telangana CM’s brother - The Siasat Daily By news.google.com Published On :: Wed, 13 Nov 2024 11:29:03 GMT Won’t back off from ‘Pharma Village’, says Telangana CM’s brother The Siasat DailyLagcherla: KTR named in remand report Deccan ChronicleEx-BRS MLA held over mob attack on Vikarabad collector Hindustan TimesVideo | Violence Over Land Row In Telangana Chief Minister's Constituency, 55 Detained NDTVGovt. charges BRS with hatching conspiracies to stall development projects for political gains The Hindu Full Article
pharma Modi-Mundipharma Pvt. Ltd. & Anr. vs Win Health Pharma Through Its ... on 13 November, 2024 By indiankanoon.org Published On :: 13.11.2024 MINI PUSHKARNA, J: I.A. No. 4172/2023 (Application under Section 124 of the Trademarks Act, 1999 read with Section 151 CPC seeking permission to challenge the validity of the defendants' trademark registrations) 1. The present application has been filed by the plaintiffs under Section 124 of the Trade Marks Act, 1999 read with Section 151 Code of Civil Procedure, 1908 ("CPC") seeking permission to challenge the validity of the defendant‟s trademark registrations. Full Article
pharma M/S. Cadila Pharmaceuticals Ltd. ... vs The Dy.Commissioner Of Income Tax, ... on 12 November, 2024 By indiankanoon.org Published On :: These cross appeals are filed by the Revenue and Assessee against order dated 12.03.2020 passed by the CIT(A)-1, Ahmedabad for the Assessment Year 2012-13. 2. The Revenue has raised the following grounds of appeal :- ITA Nos.345 & 383/Ahd/2020 Assessment Years: 2012-13 "(1) The ld. CIT(A) has erred in facts and law in deleting the transfer pricing adjustment made in respect of Corporate guarantee fees of Rs.60,83,440/- (2) The id. CIT(A) has erred in facts and law in deleting the interest disallowance of Rs.1,64,86,560/- u/s.36(1)(iii) of the Act. Full Article
pharma The Dy.Commissioner Of Income Tax, ... vs M/S. Cadila Pharmaceuticals Ltd. , ... on 12 November, 2024 By indiankanoon.org Published On :: These cross appeals are filed by the Revenue and Assessee against order dated 12.03.2020 passed by the CIT(A)-1, Ahmedabad for the Assessment Year 2012-13. 2. The Revenue has raised the following grounds of appeal :- ITA Nos.345 & 383/Ahd/2020 Assessment Years: 2012-13 "(1) The ld. CIT(A) has erred in facts and law in deleting the transfer pricing adjustment made in respect of Corporate guarantee fees of Rs.60,83,440/- (2) The id. CIT(A) has erred in facts and law in deleting the interest disallowance of Rs.1,64,86,560/- u/s.36(1)(iii) of the Act. Full Article
pharma Upper-teens EPS growth likely for Gland Pharma By www.rediff.com Published On :: Wed, 13 Nov 2024 15:25:16 +0530 Gland Pharma beat muted expectations for Q2FY25. There was increased Ebitda (Earnings before interest, taxes, depreciation and amortisation) loss at Cenexi, the CRAM subsidiary. However, overall Ebitda margin was better than expectations at 21.1 per cent. But given two years of earnings decline in FY23 and FY24, the business may have bottomed and upper-teens EPS (earnings per share) growth looks possible over next two financial years. Full Article
pharma Ex-FDA chief cleared over Tarlac pharmacy closure By www.philstar.com Published On :: Thu, 14 Nov 2024 00:00:00 +0800 The Sandiganbayan has acquitted former Food and Drug Administration chief Nela Charade Puno of graft, which stemmed from a raid and closure by the FDA of a pharmacy and wellness center in Tarlac. Full Article
pharma On Pharmaceutical Products, Health Care Products Packaging Theoretical By blogs.siliconindia.com Published On :: Of pharmaceutical products, health care products packaging theory , there are several aspects of the law we need to , inter alia: 1 , generate new theory of pharmaceutical products , not only to consider the psychological factors of... Full Article
pharma Correction: Design, synthesis, pharmacological evaluation, and in silico studies of the activity of novel spiro pyrrolo[3,4-d]pyrimidine derivatives By pubs.rsc.org Published On :: RSC Adv., 2024, 14,36351-36351DOI: 10.1039/D4RA90128B, Correction Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Abdullah Y. A. Alzahrani, Wesam S. Shehab, Asmaa H. Amer, Mohamed G. Assy, Samar M. Mouneir, Maged Abdelaziz, Atef M. Abdel HamidThe content of this RSS Feed (c) The Royal Society of Chemistry Full Article
pharma Grünenthal acquires US-company Valinor Pharma and becomes global owner of Movantik® By www.prleap.com Published On :: Mon, 22 Jul 2024 00:15:00 PDT Full Article
pharma Grünenthal and Averitas Pharma announce completion of recruitment for Phase III clinical trial with QUTENZA® in post-surgical neuropathic pain By www.prleap.com Published On :: Thu, 07 Nov 2024 01:45:00 PST - The Phase III trial AV001 aims to evaluate QUTENZA® in post-surgical neuropathic pain (PSNP), a debilitating complication of surgery occurring after approximately 10 percent of all surgical procedures[1], thus affecting more than 3 million people with surgical procedures per year in the U.S.[2] Full Article
pharma Big Pharma Given Total Liability Shield for Vaccines By essentialemmes.blogspot.com Published On :: Sun, 27 Feb 2011 04:57:00 +0000 U.S. Supreme Court Betrays U.S. Consumer: Big Pharma Given Total Liability Shield for Vaccines -- Read more from Barbara Loe Fisher of the National Vaccine Information Center: http://www.nvic.org/NVIC-Vaccine-News/February-2011/NVIC-Cites--Betrayal--of-Consumers-by-U-S--Supreme.aspx Full Article
pharma Africa: Prosper Africa's Tech for Trade Alliance Announces a Pharmaceutical Tracing Pilot in South Africa as Part of U.S. Digital Transformation with Africa (DTA) Strategy By allafrica.com Published On :: Tue, 12 Nov 2024 17:15:00 GMT [Prosper Africa] Prosper Africa's Tech for Trade Alliance (AT4T) is launching its latest pilot in Africa to field test a digital platform intended to bring visibility to Africa's drug supply chains, creating a more transparent, efficient, and safe commercial market for medications. Full Article Africa Economy Business and Finance External Relations Health and Medicine International Organizations and Africa Trade United States Canada and Africa
pharma South Africa: Pharmaceutical Corporations Must Make Insulin Pens Available at $1 Per Pen By allafrica.com Published On :: Wed, 13 Nov 2024 13:17:36 GMT [MSF] Ahead of World Diabetes Day, Doctors Without Borders (MSF) called on pharmaceutical corporations Eli Lilly, Novo Nordisk, Sanofi, and all insulin manufacturers to take urgent action to increase access to diabetes treatment in low- and middle-income countries by immediately making insulin* pen injection devices available at US$1 (R17,81) per pen. Full Article External Relations Health and Medicine International Organizations and Africa South Africa Southern Africa
pharma Update (15.01.2015): Pharmazentralnummer [DE] By WWW.Pruefziffernberechnung.DE Published On :: Full Article
pharma I will never delay flu jab again - pharmacy boss By www.bbc.com Published On :: Tue, 12 Nov 2024 06:18:28 GMT Tania Cork felt she might need an inhaler for the rest of her life after catching flu last year. Full Article
pharma Exploring the Key Informational, Ethical and Legal Concerns to the Development of Population Genomic Databases for Pharmacogenomic Research By Published On :: Full Article
pharma Fail Often, Fail Big, and Fail Fast? Learning from Small Failures and R&D Performance in the Pharmaceutical Industry By amj.aom.org Published On :: Thu, 02 Apr 2015 14:37:53 +0000 Do firms learn from their failed innovation attempts? Answering this question is important because failure is an integral part of exploratory learning. In this study, we explore whether and under what circumstances firms learn from their small failures in experimentation. Building on organizational learning literature, we examine the conditions under which prior failures influence firms' R&D output amount and quality. An empirical analysis of voluntary patent expirations (i.e., patents that firms give up by not paying renewal fees) in 97 pharmaceutical firms between 1980 and 2002 shows that the number, importance, and timing of small failures are associated with a decrease in R&D output (patent count) but an increase in the quality of the R&D output (forward citations to patents). Exploratory interviews suggest that the results are driven by a multi-level learning process from failures in pharmaceutical R&D. The findings contribute to the organizational learning literature by providing a nuanced view of learning from failures in experimentation. Full Article
pharma 28th Singapore Pharmacy Congress By www.pss.org.sg Published On :: Wed, 23 Oct 2019 08:55:15 +0000 Full Article
pharma 29th Singapore Pharmacy Congress By www.pss.org.sg Published On :: Wed, 23 Oct 2019 09:13:20 +0000 Full Article
pharma Pharmacists in COVID-19 Pandemic By www.pss.org.sg Published On :: Thu, 30 Apr 2020 08:32:46 +0000 An exclusive supplementary bulletin on what goes behind the scene in the pharmacies that are at the forefront in the COVID-19 Pandemic. Kudos to our pharmacists and pharmacy technicians working tirelessly to ensure that everything is still business as usual for our patients and fellow healthcare workers. Full Article
pharma 4th Annual Community Pharmacy Symposium By www.pss.org.sg Published On :: Fri, 12 Jul 2024 07:30:16 +0000 The Pharmaceutical Society of Singapore’s Community Chapter proudly hosted the 4th annual Community Pharmacy Symposium on 25th May 2024. Supported by POMConnect and DocMed Technology, this virtual gathering united more than a hundred pharmacists representing diverse sectors of the pharmacy fraternity. Full Article
pharma Pharmacy Week 2024 By www.pss.org.sg Published On :: Fri, 12 Jul 2024 07:51:15 +0000 Greetings from the PSS Pharmacy Week 2024 Organizing Committee! Full Article
pharma PSS Telepharmacy and Tele-Pharmaceutical Care Services Guidelines (Revised 2024) By www.pss.org.sg Published On :: Thu, 12 Sep 2024 09:00:07 +0000 A revised version of the PSS Telepharmacy and Tele-Pharmaceutical Care Services Guidelines was published at the end of July 2024, featuring some exciting changes. With the revision, Telepharmacy services can now be provided under two scenarios: Situation 1: The patient calls a qualified pharmacist at a licensed pharmacy premises, with assistance from a trained staff member or pharmacy technician from another licensed pharmacy, to receive advice and medications. Full Article
pharma 23rd Asian Conference on Clinical Pharmacy By www.pss.org.sg Published On :: Thu, 12 Sep 2024 09:01:12 +0000 By Ms Lee Chiawli, Ms Lim Kae Shin, Dr Kevin Yap & Assoc Prof Doreen Tan Full Article
pharma 33rd Singapore Pharmacy Congress By www.pss.org.sg Published On :: Thu, 12 Sep 2024 09:07:50 +0000 Full Article
pharma Pharmacy Week 2024 By www.pss.org.sg Published On :: Thu, 12 Sep 2024 09:08:38 +0000 Full Article
pharma Ethics in Pharmacy By www.pss.org.sg Published On :: Wed, 09 Feb 2022 06:24:36 +0000 Full Article
pharma 33rd Singapore Pharmacy Congress By www.pss.org.sg Published On :: Wed, 07 Feb 2024 06:24:03 +0000 ‘Interlacing Health: Weaving the Future of Pharmacy’ Congress to be held on 5–6 October 2024 at the Grand Copthorne Waterfront Hotel, Singapore. Find out more: https://pharmacycongress.org.sg/ Full Article
pharma Pharmacy Week 2024 By www.pss.org.sg Published On :: Wed, 14 Aug 2024 09:59:10 +0000 In celebration of World Pharmacist Day and Pharmacy Week this September, the Pharmaceutical Society of Singapore (PSS) is proud to present to you, Pharmacy Week 2024 themed “Just Ask! Know Your Medicines!” Join us for a fantastic week of celebration and learning! Pharmacy Week 2024: 23-29th September 2024 Live Carnival: 29th September 2024 (Sunday) Location: heartbeat@bedok Time: 10:00AM to 2:30PM Save the date for our live carnival! Full Article
pharma Say a prayer for Big Pharma By www.washingtontimes.com Published On :: Mon, 11 Nov 2024 14:46:06 -0500 An underreported aspect of President-elect Donald Trump's victory last Tuesday night was how his historic alliance with Robert F. Kennedy Jr. will shift our health care landscape. Full Article
pharma COVID-19 pandemic: OSHA issues guidance for retail pharmacy workers By www.safetyandhealthmagazine.com Published On :: Wed, 17 Jun 2020 00:00:00 -0400 Washington — To help protect retail pharmacy workers from exposure to COVID-19, OSHA has issued a safety alert. Full Article
pharma Pharmactive's Aged Black Garlic: Take it to Heart By www.preparedfoods.com Published On :: Tue, 14 Apr 2020 00:00:00 -0400 An in-vivo animal study revealed that aged black garlic extract (Pharmactive Biotech Products, S.L. ABG10+®) containing S-allyl-cysteine (SAC) and polyphenols could help promote vascular health. Full Article
pharma Pharmactive’s New Generation of Aged Black Garlic Shows Cardioprotective Effects By www.preparedfoods.com Published On :: Thu, 14 May 2020 00:00:00 -0400 An in vivo animal study revealed that aged black garlic extract (Pharmactive Biotech Products, S.L. ABG10+®) containing S-allyl-cysteine (SAC) and polyphenols could help promote vascular health. ABG10+, a Nutraingredients Asia Award-winning proprietary black garlic extract formulation, demonstrated that supplementation with this unique compound could help maintain proper cardiovascular function, balance lipids, and decrease the risk of atherosclerosis. Full Article
pharma Pharmactive Biotech Products: Boost Sex Drive, Function By www.preparedfoods.com Published On :: Fri, 28 Oct 2022 12:30:00 -0400 Pharmactive Biotech Products, S.L.U., launches Liboost®, a novel botanical extract of Damiana (Turnera diffusa), as the first formulation to help enhance sexual function in both men and women. Its sexual performance boosting capabilities have been confirmed in a consumer study conducted by the company yielding impressive results. Full Article
pharma Edward Trautner (1890–1978), a pioneer of psychopharmacology By ifp.nyu.edu Published On :: Tue, 29 Oct 2024 21:53:10 +0000 Volume 33, Issue 1, January-March 2024, Page 1-56. Read the full article › The post Edward Trautner (1890–1978), a pioneer of psychopharmacology was curated by information for practice. Full Article History
pharma High-throughput nanoscale crystallization of dihydropyridine active pharmaceutical ingredients By journals.iucr.org Published On :: 2023-12-21 Single-crystal X-ray diffraction analysis of small molecule active pharmaceutical ingredients is a key technique in the confirmation of molecular connectivity, including absolute stereochemistry, as well as the solid-state form. However, accessing single crystals suitable for X-ray diffraction analysis of an active pharmaceutical ingredient can be experimentally laborious, especially considering the potential for multiple solid-state forms (solvates, hydrates and polymorphs). In recent years, methods for the exploration of experimental crystallization space of small molecules have undergone a `step-change', resulting in new high-throughput techniques becoming available. Here, the application of high-throughput encapsulated nanodroplet crystallization to a series of six dihydropyridines, calcium channel blockers used in the treatment of hypertension related diseases, is described. This approach allowed 288 individual crystallization experiments to be performed in parallel on each molecule, resulting in rapid access to crystals and subsequent crystal structures for all six dihydropyridines, as well as revealing a new solvate polymorph of nifedipine (1,4-dioxane solvate) and the first known solvate of nimodipine (DMSO solvate). This work further demonstrates the power of modern high-throughput crystallization methods in the exploration of the solid-state landscape of active pharmaceutical ingredients to facilitate crystal form discovery and structural analysis by single-crystal X-ray diffraction. Full Article text
pharma NY Biopharma Shares Promising Clinical Data By www.streetwisereports.com Published On :: Fri, 18 Oct 2024 00:00:00 PST Source: Dr. Ram Selvaraju 10/18/2024 Anavex Life Sciences Corp. (AVXL:NASDAQ) recently released encouraging preliminary electroencephalography (EEG) biomarker results from Part A of the ongoing Phase 2 clinical study of ANAVEX3-71 for schizophrenia treatment, according to an H.C. Wainright & Co. research note.H.C. Wainwright & Co. analyst Dr. Ram Selvaraju, in a research report published on October 18, 2024, reiterated a Buy rating on Anavex Life Sciences Corp. (AVXL:NASDAQ) with a price target of US$40.00. The report follows Anavex's announcement of encouraging preliminary electroencephalography (EEG) biomarker results from Part A of the ongoing Phase 2 clinical study of ANAVEX3-71 for schizophrenia treatment. Selvaraju highlighted the significance of these results, stating, "Preliminary results demonstrated a dose-dependent effect of ANAVEX3-71 on two key EEG biomarkers in patients with schizophrenia. Treatment with ANAVEX3-71 vs. placebo resulted in improvements in 40 Hz Auditory Steady-State Response (ASSR) Inter Trial Coherence (ITC) and Resting State Alpha Power." The analyst viewed these developments positively, noting, "These results provide evidence of CNS target engagement and potential therapeutic effects of ANAVEX3-71 in schizophrenia. The observed changes reversed known EEG and ERP biomarker abnormalities associated with schizophrenia." Regarding Anavex's lead candidate, blarcamesine, Selvaraju stated, "Anavex remains committed to completing the Marketing Authorization Application (MAA) submission to the European Medicines Agency (EMA) under the Centralized Procedure petitioning for approval of blarcamesine for treatment of Alzheimer's disease (AD) in 4Q24." The report also highlighted Anavex's progress with other clinical programs, including a pivotal Phase 2b/3 trial in Parkinson's disease and potential trials in Rett syndrome and Fragile X Syndrome. Selvaraju's valuation methodology for Anavex Life Sciences is based on a discounted cash flow (DCF) approach. He explained, "We utilize a discounted cash flow (DCF)-driven methodology, which ascribes a total value of roughly US$3.25B to blarcamesine alone without ascribing value to any other pipeline assets. We employ a 50% probability of approval in Rett syndrome; 60% in Parkinson's disease dementia (PDD); and 50% in AD." The analyst added, "Further, we apply a 12% discount rate and 1% terminal growth rate. We derive a total firm value of ~US$3.4B, which yields a 12-month price objective of US$40 per share, assuming 84.8M shares outstanding as of end-F2Q25." Selvaraju also outlined several risk factors, including potential negative clinical data, regulatory approval challenges, and commercialization difficulties. In conclusion, H.C. Wainwright & Co.'s maintenance of a Buy rating and US$40 price target reflects a positive outlook on Anavex Life Sciences' clinical progress and potential in developing treatments for neurological disorders. The share price at the time of the report of US$5.51 represents a potential return of approximately 626% to the analyst's target price, highlighting the significant upside potential if the company's clinical development plans prove successful.Important Disclosures: This article does not constitute investment advice and is not a solicitation for any investment. Streetwise Reports does not render general or specific investment advice and the information on Streetwise Reports should not be considered a recommendation to buy or sell any security. Each reader is encouraged to consult with his or her personal financial adviser and perform their own comprehensive investment research. By opening this page, each reader accepts and agrees to Streetwise Reports' terms of use and full legal disclaimer. Streetwise Reports does not endorse or recommend the business, products, services or securities of any company. This article does not constitute medical advice. Officers, employees and contributors to Streetwise Reports are not licensed medical professionals. Readers should always contact their healthcare professionals for medical advice. For additional disclosures, please click here. Disclosures for H.C. Wainwright & Co., Anavex Life Sciences Corp., October 18, 2024. This material is confidential and intended for use by Institutional Accounts as defined in FINRA Rule 4512(c). It may also be privileged or otherwise protected by work product immunity or other legal rules. If you have received it by mistake, please let us know by e-mail reply to unsubscribe@hcwresearch.com and delete it from your system; you may not copy this message or disclose its contents to anyone. The integrity and security of this message cannot be guaranteed on the Internet. H.C. WAINWRIGHT & CO, LLC RATING SYSTEM: H.C. Wainwright employs a three tier rating system for evaluating both the potential return and risk associated with owning common equity shares of rated firms. The expected return of any given equity is measured on a RELATIVE basis of other companies in the same sector. The price objective is calculated to estimate the potential movements in price that a given equity could reach provided certain targets are met over a defined time horizon. Price objectives are subject to external factors including industry events and market volatility. H.C. Wainwright & Co, LLC (the “Firm”) is a member of FINRA and SIPC and a registered U.S. Broker-Dealer. I, Raghuram Selvaraju, Ph.D. , certify that 1) all of the views expressed in this report accurately reflect my personal views about any and all subject securities or issuers discussed; and 2) no part of my compensation was, is, or will be directly or indirectly related to the specific recommendation or views expressed in this research report; and 3) neither myself nor any members of my household is an officer, director or advisory board member of these companies. None of the research analysts or the research analyst’s household has a financial interest in the securities of Anavex Life Sciences Corp. (including, without limitation, any option, right, warrant, future, long or short position). As of September 30, 2024 neither the Firm nor its affiliates beneficially own 1% or more of any class of common equity securities of Anavex Life Sciences Corp.. Neither the research analyst nor the Firm knows or has reason to know of any other material conflict of interest at the time of publication of this research report. The research analyst principally responsible for preparation of the report does not receive compensation that is based upon any specific investment banking services or transaction but is compensated based on factors including total revenue and profitability of the Firm, a substantial portion of which is derived from investment banking services. Mr. Selvaraju, who is [the][an] author of this report, is the Chairman of and receives compensation from Relief Therapeutics Holding SA, a Swiss, commercial-stage biopharmaceutical company identifying, developing and commercializing novel, patent protected products in selected specialty, rare and ultra-rare disease areas on a global basis ("Relief"). You should consider Mr. Selvaraju's position with Relief when reading this research report. The firm or its affiliates received compensation from Anavex Life Sciences Corp. for non-investment banking services in the previous 12 months. The Firm or its affiliates did not receive compensation from Anavex Life Sciences Corp. for investment banking services within twelve months before, but will seek compensation from the companies mentioned in this report for investment banking services within three months following publication of the research report. The Firm does not make a market in Anavex Life Sciences Corp. as of the date of this research report. The securities of the company discussed in this report may be unsuitable for investors depending on their specific investment objectives and financial position. Past performance is no guarantee of future results. This report is offered for informational purposes only, and does not constitute an offer or solicitation to buy or sell any securities discussed herein in any jurisdiction where such would be prohibited. This research report is not intended to provide tax advice or to be used to provide tax advice to any person. Electronic versions of H.C. Wainwright & Co., LLC research reports are made available to all clients simultaneously. No part of this report may be reproduced in any form without the expressed permission of H.C. Wainwright & Co., LLC. Additional information available upon request. H.C. Wainwright & Co., LLC does not provide individually tailored investment advice in research reports. This research report is not intended to provide personal investment advice and it does not take into account the specific investment objectives, financial situation and the particular needs of any specific person. Investors should seek financial advice regarding the appropriateness of investing in financial instruments and implementing investment strategies discussed or recommended in this research report. H.C. Wainwright & Co., LLC’s and its affiliates’ salespeople, traders, and other professionals may provide oral or written market commentary or trading strategies that reflect opinions that are contrary to the opinions expressed in this research report. H.C. Wainwright & Co., LLC and its affiliates, officers, directors, and employees, excluding its analysts, will from time to time have long or short positions in, act as principal in, and buy or sell, the securities or derivatives (including options and warrants) thereof of covered companies referred to in this research report. The information contained herein is based on sources which we believe to be reliable but is not guaranteed by us as being accurate and does not purport to be a complete statement or summary of the available data on the company, industry or security discussed in the report. All opinions and estimates included in this report constitute the analyst’s judgment as of the date of this report and are subject to change without notice. Securities and other financial instruments discussed in this research report: may lose value; are not insured by the Federal Deposit Insurance Corporation; and are subject to investment risks, including possible loss of the principal amount invested. ( Companies Mentioned: AVXL:NASDAQ, ) Full Article
pharma Pharma Stock Has Significant Upside Potential, Analyst Says By www.streetwisereports.com Published On :: Mon, 04 Nov 2024 00:00:00 PST Source: Dr. Joseph Pantginis 11/04/2024 "We believe significant upside potential exists," H.C. Wainwright & Co. analysts wrote about Lexicon Pharmaceuticals Inc. (LXRX:NASDAQ) in an updated research note.H.C. Wainwright & Co. analysts Dr. Joseph Pantginis, Dr. Lander Egaña Gorroño, Dr. Joshua Korsen, Dr. Matthew Keller, and Dr. Sara Nik, in a research report published on November 4, 2024, maintained their Buy rating on Lexicon Pharmaceuticals Inc. (LXRX:NASDAQ) with a price target of US$6.00. The report follows Lexicon's presentation of preclinical data for LX9851, its ACSL5 inhibitor for obesity, at ObesityWeek 2024. The analysts highlighted key findings from the presentations, stating, "LX9851 promotes reduction of fat mass without affecting lean body mass" and "LX9851 improves and sustains GLP-1 RA-mediated weight loss, even after semaglutide discontinuation." They added that "Mechanistic studies suggest that LX9851-mediated ACSL5 inhibition activates the ileal brake." Regarding the drug's potential, they noted, "LX9851 is a first-in-class, oral small molecule ACSL5 inhibitor designed to enhance and maintain weight loss promoted by incretin mimetics (GLP-1 receptor agonists), and offer improved treatment alternatives for obesity and related metabolic disorders." The report also addressed recent developments with sotagliflozin, detailing the AdCom voting results and potential scenarios for FDA action. The analysts stated, "Although we anticipate favorable feedback from the agency regarding eGFR ≥60 to <90 range, our bet is that a confirmatory trial may be required to validate sota's efficacy in this subpopulation and obtain approval." H.C. Wainwright & Co.'s valuation methodology is based on a clinical net present value (NPV) model. The analysts explained, "Our valuation is based on our clinical net present value (NPV) model, which allows us to flex multiple assumptions affecting a drug's profile. We currently value Lexicon solely on sotagliflozin sales in the U.S. for HF (INPEFA), HCM, and LX9211 for DPNP." They added, "We believe significant upside potential exists, based on: (1) attaining higher market penetration for HF, and HCM; and (2) adding the earlier stage assets." In conclusion, H.C. Wainwright & Co.'s maintenance of their Buy rating and US$6 price target reflects confidence in Lexicon's pipeline potential, particularly with LX9851 and sotagliflozin. The share price at the time of the report of US$1.22 represents a potential return of approximately 392% to the analysts' target price, highlighting the significant upside potential if the company's development programs prove successful. Sign up for our FREE newsletter at: www.streetwisereports.com/get-newsImportant Disclosures: This article does not constitute investment advice and is not a solicitation for any investment. Streetwise Reports does not render general or specific investment advice and the information on Streetwise Reports should not be considered a recommendation to buy or sell any security. Each reader is encouraged to consult with his or her personal financial adviser and perform their own comprehensive investment research. By opening this page, each reader accepts and agrees to Streetwise Reports' terms of use and full legal disclaimer. Streetwise Reports does not endorse or recommend the business, products, services or securities of any company. This article does not constitute medical advice. Officers, employees and contributors to Streetwise Reports are not licensed medical professionals. Readers should always contact their healthcare professionals for medical advice. For additional disclosures, please click here. Disclosures for H.C. Wainwright & Co., Lexicon Pharmaceuticals Inc., November 4, 2024 This material is confidential and intended for use by Institutional Accounts as defined in FINRA Rule 4512(c). It may also be privileged or otherwise protected by work product immunity or other legal rules. If you have received it by mistake, please let us know by e-mail reply to unsubscribe@hcwresearch.com and delete it from your system; you may not copy this message or disclose its contents to anyone. The integrity and security of this message cannot be guaranteed on the Internet. H.C. WAINWRIGHT & CO, LLC RATING SYSTEM: H.C. Wainwright employs a three tier rating system for evaluating both the potential return and risk associated with owning common equity shares of rated firms. The expected return of any given equity is measured on a RELATIVE basis of other companies in the same sector. The price objective is calculated to estimate the potential movements in price that a given equity could reach provided certain targets are met over a defined time horizon. Price objectives are subject to external factors including industry events and market volatility. H.C. Wainwright & Co, LLC (the “Firm”) is a member of FINRA and SIPC and a registered U.S. Broker-Dealer. I, Joseph Pantginis, Ph.D., Lander Egaña Gorroño, Ph.D., Joshua Korsen, Ph.D., Matthew Keller, Ph.D. and Sara Nik, Ph.D. , certify that 1) all of the views expressed in this report accurately reflect my personal views about any and all subject securities or issuers discussed; and 2) no part of my compensation was, is, or will be directly or indirectly related to the specific recommendation or views expressed in this research report; and 3) neither myself nor any members of my household is an officer, director or advisory board member of these companies. None of the research analysts or the research analyst’s household has a financial interest in the securities of Lexicon Pharmaceuticals, Inc. (including, without limitation, any option, right, warrant, future, long or short position). As of September 30, 2024 neither the Firm nor its affiliates beneficially own 1% or more of any class of common equity securities of Lexicon Pharmaceuticals, Inc.. Neither the research analyst nor the Firm knows or has reason to know of any other material conflict of interest at the time of publication of this research report. The research analyst principally responsible for preparation of the report does not receive compensation that is based upon any specific investment banking services or transaction but is compensated based on factors including total revenue and profitability of the Firm, a substantial portion of which is derived from investment banking services. The firm or its affiliates received compensation from Lexicon Pharmaceuticals, Inc. for non-investment banking services in the previous 12 months. The Firm or its affiliates did not receive compensation from Lexicon Pharmaceuticals, Inc. for investment banking services within twelve months before, but will seek compensation from the companies mentioned in this report for investment banking services within three months following publication of the research report. The Firm does not make a market in Lexicon Pharmaceuticals, Inc. as of the date of this research report. The securities of the company discussed in this report may be unsuitable for investors depending on their specific investment objectives and financial position. Past performance is no guarantee of future results. This report is offered for informational purposes only, and does not constitute an offer or solicitation to buy or sell any securities discussed herein in any jurisdiction where such would be prohibited. This research report is not intended to provide tax advice or to be used to provide tax advice to any person. Electronic versions of H.C. Wainwright & Co., LLC research reports are made available to all clients simultaneously. No part of this report may be reproduced in any form without the expressed permission of H.C. Wainwright & Co., LLC. Additional information available upon request. H.C. Wainwright & Co., LLC does not provide individually tailored investment advice in research reports. This research report is not intended to provide personal investment advice and it does not take into account the specific investment objectives, financial situation and the particular needs of any specific person. Investors should seek financial advice regarding the appropriateness of investing in financial instruments and implementing investment strategies discussed or recommended in this research report. H.C. Wainwright & Co., LLC’s and its affiliates’ salespeople, traders, and other professionals may provide oral or written market commentary or trading strategies that reflect opinions that are contrary to the opinions expressed in this research report. H.C. Wainwright & Co., LLC and its affiliates, officers, directors, and employees, excluding its analysts, will from time to time have long or short positions in, act as principal in, and buy or sell, the securities or derivatives (including options and warrants) thereof of covered companies referred to in this research report. The information contained herein is based on sources which we believe to be reliable but is not guaranteed by us as being accurate and does not purport to be a complete statement or summary of the available data on the company, industry or security discussed in the report. All opinions and estimates included in this report constitute the analyst’s judgment as of the date of this report and are subject to change without notice. Securities and other financial instruments discussed in this research report: may lose value; are not insured by the Federal Deposit Insurance Corporation; and are subject to investment risks, including possible loss of the principal amount invested. ( Companies Mentioned: LXRX:NASDAQ, ) Full Article
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