technique

Climate Intervention Is Not a Replacement for Reducing Carbon Emissions - Proposed Intervention Techniques Not Ready for Wide-Scale Deployment

There is no substitute for dramatic reductions in greenhouse gas emissions to mitigate the negative consequences of climate change, a National Research Council committee concluded in a two-volume evaluation of proposed climate-intervention techniques.




technique

Clinical Investigations of Mitochondrial Replacement Techniques Are ‘Ethically Permissible’ If Significant Conditions Are Met, Says New Report

Conducting clinical investigations of mitochondrial replacement techniques (MRT) in humans is ethically permissible as long as significant conditions and principles are met, says a new report from the National Academies of Sciences, Engineering, and Medicine.




technique

IAVSA (International Association of Voice Stress Analysts) RELEASES 2nd Edition 2024 of the JCAT - JOURNAL OF CREDIBILITY ASSESSMENT TECHNIQUES

IAVSA (International Association of Voice Stress Analysts) Training Firm has released the 2nd Edition 2024 of the JCAT - Journal of Credibility Assessment Techniques as related to the Voice Stress Industry for all users worldwide.




technique

Innovative Budgeting Techniques

Organizer: Government Finance Officers Association of British Columbia
Location: Vancouver




technique

ETSI releases new report enabling more transparent security techniques

Sophia Antipolis, 6 March 2023

The ETSI group on Encrypted Traffic Integration (ISG ETI) is pleased to announce the release of the group report GR-ETI-002 “Requirements definition and analysis”, the next step for the problems previously outlined in the report GR-ETI-001 “Problem Statement”.

Read More...




technique

Tenable Research to Discuss Cloud Security Attack Techniques and Detection Strategies at fwd:cloudsec Europe 2024

Tenable®, the exposure management company, announced today that Shelly Raban, senior cloud security researcher for Tenable, will give a presentation at fwd:cloudsec Europe 2024, taking place on 17 September, 2024 in Brussels, Belgium.

During the session titled, “Who Watches the Watchmen? Stealing Credentials from Policy-as-Code Engines (and Beyond),” Raban will explore techniques adversaries use to exploit modern policy-as-code and Infrastructure-as-code (IaC) domain-specific languages (DSLs), compromise cloud identities and exfiltrate sensitive data. Raban will conclude her presentation by sharing various detection strategies that cyber defenders can implement to detect malicious activity. 

The session will be hosted in the Main Room from 2:50 - 3:10 pm CEST. 

More information on the event is available on the fwd:cloudsec Europe website

More information about Tenable Cloud Security is available at: https://www.tenable.com/products/tenable-cloud-security 

About Tenable

Tenable® is the exposure management company, exposing and closing the cybersecurity gaps that erode business value, reputation and trust. The company’s AI-powered exposure management platform radically unifies security visibility, insight and action across the attack surface, equipping modern organizations to protect against attacks from IT infrastructure to cloud environments to critical infrastructure and everywhere in between. By protecting enterprises from security exposure, Tenable reduces business risk for more than 44,000 customers around the globe. Learn more at tenable.com

###

Media Contact:

Tenable

tenablepr@tenable.com




technique

Moving through grief : proven techniques for finding your way after any loss / Gretchen Kubacky, PsyD.

Overcoming your pain-proven strategies for grief recovery Coping with loss is difficult, but that doesn't mean you have to suffer alone. Based on the proven-effective acceptance and commitment therapy (ACT) treatment, Moving Through Grief provides simple and effective techniques to help you get unstuck and start living a rich and fulfilling life again, loss and all. ACT is all about embracing what hurts and committing to actions that will improve and enrich your life. Whether you're dealing with the loss of a loved one, your health, home, or even career, Moving Through Grief provides you with creative exercises that will help you work through your pain and reconnect with the things you love. In Moving Through Grief, you will learn: - How you can show up for your life and experience joy and satisfaction again, even as you work through the pain of your loss -Ddiscover how the six tools of ACT-values, committed action, acceptance, being present, cognitive diffusion, and self-as-context-can ease your pain and aid with the healing process - And make real progress towards feeling like yourself again with straightforward exercises, like identifying your values and setting realistic goals. Find out how ACT can change the way you relate to your pain with Moving Through Grief.




technique

Enhancing Automated NDT: Leveraging Advanced 3D Phased Array Scanning and C-Scan Mapping Techniques for Aerospace Applications

The aerospace industry relies on advanced nondestructive testing (NDT) to ensure safety and reliability. Automated technologies, such as phased arrays and 3D scanning, enhance defect detection in aircraft structures, reducing human error. This overview emphasizes the importance of these advancements.




technique

Canadian Blood Services research engineer applies network modelling techniques and mentorship skills to benefit Canada’s Lifeline

Canadian Blood Services research engineer applies network modelling techniques and mentorship skills to benefit Canada’s Lifeline


Tuesday, October 22, 2024 Dr. Emily Freeman

Dr. John Blake is a research engineer at Canadian Blood Services and a Professor in the Department of Industrial Engineering at Dalhousie University. Based in Halifax, Nova Scotia, Dr. Blake and his trainees use engineering principles and various computer-based optimization techniques to inform large scale decisions at Canadian Blood Services.  

Applying network modelling to biologics  

To some, it may be surprising to learn that there is such opportunity to integrate engineering into the health-care focused setting of Canadian Blood Services. However, as Dr. Blake explains, the same engineering principles that apply to the development and quality assurance of other products also apply to biologics such as blood, stem cells and organs. One of these classic engineering approaches currently applied to improving operations at Canadian Blood Services is network modelling.  

Network modelling is a computer-based method that creates a virtual representation of objects and their relation to each other. The resulting models are particularly useful for maintaining adaptability in the collection of blood donations, as well as the distribution and inventory management strategies that allow Canadian Blood Services to remain a safe and reliable provider of life-saving products. 

Dr. Blake making friends while walking the Camino de Santiago in Spain

Contributing to efficiency and sustainability in Canada’s Lifeline  

For Dr. Blake’s team, modelling is not about the data acquired but rather how they can turn existing data into real life change. Part of this approach is ensuring that Canadian Blood Services is asking the right questions when it comes to allocating resources. For example, Dr. Blake has worked on models to assess how changing stem cell donor recruitment will affect the number of matches for Canadian patients. By modelling things such as recruitment approaches, Dr. Blake’s work assists Canadian Blood Services to consistently identify ways to improve Canada’s Lifeline.

Recently, Dr. Blake has also been applying this method to optimize the number and location of mobile and permanent donor facilities across the nation. This redesign of the donation facility network will address the growing demand for donations by bringing Canadian Blood Services’ facilities closer to the donors. 

“I have waited my entire career for a problem of this type – it is truly a once in a lifetime opportunity.”

Dr. John Blake, Canadian Blood Services Research Engineer

Securing the future of Canada’s Lifeline  

To sustain a safe and effective blood system in Canada for years to come, network modelling and optimization is a never-ending process. This is one of the reasons that Dr. Blake is committed to securing the future of transfusion and transplantation systems by training and mentoring the next generation of engineers. In fact, seeing his former students join Canadian Blood Services and dedicate their talents to improving the future of Canada’s Lifeline is one of Dr. Blake’s proudest achievements.  

One of Dr. Blake’s former students, Matt Nelson, is now an industrial engineer at Canadian Blood Services.  

“In my role, I use systematic thinking to build and run complex models; collect and analyze the required data; produce useful results; and explain these results to non-technical leaders on a regular basis,” Matt says. Recently, Matt contributed to the launch and expansion of pathogen-reduced platelets, a new product that was implemented across Canadian Blood Services production sites starting in 2022. The implementation of pathogen-reduced platelets has provided an additional layer of safety for recipients by reducing the risk of potential transfusion-transmitted pathogens without compromising the quality of the component. Matt credited Dr. Blake in helping him develop the necessary skills he now dedicates to safeguarding Canada’s Lifeline:  

“Dr. Blake was the professor who introduced me to the uses of simulation to understand complex non-linear systems. This type of system is very common in situations that have a lot of variability – like the blood system – and simulation allows for exploration of the response of the system to changes.” 

Matt Nelson, Canadian Blood Services Industrial Engineer

Over the years, Dr. Blake’s ongoing modelling work and mentorship activities have also led to many recognitions and awards, but he is most proud of being recognized as Professor of the Year by Dalhousie Undergraduate students, and with awards for his contributions to the Canadian Operational Research Society. He has even the earned the distinction of being Dalhousie’s first engineer to be awarded grant funding from the tri-council agency, Social Sciences and Humanities Research Council (SSHRC). 

“I am proud to work on projects that have a measurable impact on people’s health and well-being,” Dr. Blake says. “I am forever grateful to Dr. Dana Devine for first giving me the opportunity to serve Canadians in this role at Canadian Blood Services.” 


Canadian Blood Services – Driving world-class innovation

Through discovery, development and applied research, Canadian Blood Services drives world-class innovation in blood transfusion, cellular therapy and transplantation—bringing clarity and insight to an increasingly complex healthcare future. Our dedicated research team and extended network of partners engage in exploratory and applied research to create new knowledge, inform and enhance best practices, contribute to the development of new services and technologies, and build capacity through training and collaboration. Find out more about our research impact.   

The opinions reflected in this post are those of the author and do not necessarily reflect the opinions of Canadian Blood Services nor do they reflect the views of Health Canada or any other funding agency.  

Related blog posts


Tuesday, March 29, 2022
Marie-Soleil Smith

This post was written by Marie-Soleil Smith, PhD Candidate in Dr. Hélène Côté’s Lab at the University of British Columbia, and edited by Dr. Geraldine Walsh, knowledge broker at Canadian Blood Services. It originally appeared on the Centre for Blood Research blog in March 2022.


Monday, January 22, 2018
Dr. Geraldine Walsh

For the latest instalment of “Meet the researcher” we chatted with Dr. John Blake, Canadian Blood Services’ research engineer and also known as “the numbers guy”.


Wednesday, June 13, 2018
Jenny Ryan

On June 5, Canadian Blood Services was honoured to accept the Canadian Operational Research Society's Omandt Solandt Award at a reception in Halifax, Nova Scotia. Michelle Rogerson, Director, Supply Chain (Atlantic), Canadian Blood Services, accepted the award on behalf of the organization. About...




technique

Control Techniques: Bypass Packages

This package has an intuitive operator touchscreen to access the HVAC H300 VFD and bypass setup options. It also displays complete system status information.




technique

Twelve high voltage cable construction techniques used worldwide

This technical article discusses twelve different methods for laying high voltage cables. Out of the ten, four are deemed conventional and eight are deemed progressive. Many various utilities and companies all across the globe are making use of them, though... Read more

The post Twelve high voltage cable construction techniques used worldwide appeared first on EEP - Electrical Engineering Portal.




technique

Achieving Success in Restorative Drying: Key Techniques and Considerations

Restorative drying is essential for returning building materials to their pre-loss condition efficiently and cost-effectively. Learn more about the critical steps and considerations, from accurate material assessment to advanced dehumidification techniques.




technique

Advanced PPE Techniques and Protection for Restorers

Use these techniques to minimize risk at jobsites and prevent the bringing home of hazardous materials.




technique

CineCentral to Spotlight Emerging Cinematic Trends and Techniques at 2023 NAB Show

Washington, D.C. -- The new CineCentral destination at the 2023 NAB Show gives attendees an opportunity to learn side-by-side with Hollywood's award-winning production professionals and gain skills with hands-on training inspired by NAB’s Cine Consortium. CineCentral is located in Central Hall (C7345) and adjacent to the Create Experiential Zone featuring sessions on Cine+Live, the burgeoning live production style where cinematic tools and storytelling is integrated into live entertainment. Additional workshops will be presented by American Cinema Editors, American Society of Cinematographers, International Cinematographers Guild/Local 600 and The Society of Camera Operators.




technique

Seminar for defence lawyers on new approaches and techniques of legal defence

Seminar
Wed, 2016-08-10 (All day) - Thu, 2016-08-11 (All day)
Almaty, Kazakhstan
The OSCE Programme Office in Astana, the National Bar Association, the Almaty Bar Association
OSCE Programme Office in Astana
Central Asia
Human rights

This training seminar is the second in a series of 2016 training events aimed at strengthening the capacity of legal community, including defence lawyers, to effectively function in accordance with novelties in criminal procedure legislation. The seminar aims to provide defence lawyers with a deeper understanding of the advocacy specifics in cases with the involvement of investigating judges. Event participants will discuss issues related to organizational and legal aspects of methodology and mechanisms for collection of evidence, application of international standards, as well as enhancing defence lawyers’ knowledge and skills on evidence deposition procedure. A separate session will be devoted to the legal ethics and principles of lawyers’ interaction with the media and social networks.

Related Stories




technique

[ K.37 (01/24) ] - Low and high frequency EMC mitigation techniques for telecommunication installations and systems - Basic EMC Recommendation

Low and high frequency EMC mitigation techniques for telecommunication installations and systems - Basic EMC Recommendation




technique

[ L.155 (11/16) ] - Low impact trenching technique for FTTx networks

Low impact trenching technique for FTTx networks




technique

[ X.1500 (2011) Amendment 12 (03/18) ] - Revised structured cybersecurity information exchange techniques

Revised structured cybersecurity information exchange techniques




technique

[ X.1214 (03/18) ] - Security assessment techniques in telecommunication/information and communication technology networks

Security assessment techniques in telecommunication/information and communication technology networks




technique

Colorito : la technique des peintres ve´nitiens a` la Renaissance /

Library - Art Library, Location - OSIZ, Call number - FOLIO ND621.V5 H63 2015




technique

Computational Intelligence Techniques in Health Care

Location: Electronic Resource- 




technique

Modeling risk applying Monte Carlo simulation, real options analysis, forecasting, and optimization techniques

Location: Electronic Resource- 




technique

Data Mining Techniques for the Life Sciences

Location: Electronic Resource- 




technique

Linear circuit transfer functions : an introduction to fast analytical techniques

Location: Electronic Resource- 




technique

Microwave amplifier and active circuit design using the real frequency technique

Location: Electronic Resource- 




technique

Sound systems : design and optimization : modern techniques and tools for sound system design and alignment

Location: Engineering Library- TK7881.4.M42 2016




technique

Learning Logic Pro X: Exploring Interfaces, Choosing a Microphone, and Basic Editing Techniques

In the second episode of his series learning Logic Pro X for Mac, Ming introduces two main sections. In the first part, Ming explains why the Interface and Microphone are important in professional recording and music editing, and how the Interface works. Ming uses logic to demonstrate how to slice and dice regions, efficiently move regions to neighboring regions, and export and merge projects into different audio formats. These shortcuts include:

Command + B: Bounce your project

Option + [ ] "Align the current region to the left or right of other regions.

Pause or play: Space bar.

See also: Learning Logic Pro X: Episode 1 - Creating a New Project

Note: Logic Pro X is a professional grade digital audio workstation (DAW) and MIDI sequencer. It is suggested to have some familiarity with Digital Audio Workstations to get the most from this series.




technique

Kara Helps Her Man Work on His 'Technique'



Kara might have a future as a sex therapist.




technique

Quick Rapport Technique.

As most fundraisers know, building rapport with donors keeps them on the phone and listening to your request. Rapport isn't a clever trick; it is a means of showing donors that you are interested in them and that you have at least some small things in common. We build rapport in almost every conversation we have whether on or off of the phone. Building rapport with someone you've just called for the first time can be a little harder, but it is certainly possible.

One simple technique for rapport building is knowing the state nicknames or motto's of the states that you're dialing into. Asking a donor how things are going in the Equality State rather than simply how things are going, makes your question more intimate. Donors really do open up when you take a personal interest in them. Listed below are the state nicknames.

StateNickname(s)
 Alabama
(No official nickname)[1]
 Alaska
 Arizona
 Arkansas
 California
  • El Dorado State
  • The Golden State[12][13] (previously used on license plates)
  • The Land of Sunshine and Opportunity
  • Golden West
  • Grape State
  • Land of Milk and Honey
  • Land of Fruits and Nuts
  • Where Stars Are Buried
  • The Cereal Bowl of the Nation
  • The Eureka State [14]
  • The Bear State (or Republic)
  • The Sunshine State (in disuse) (c.f. FL)
 Colorado
 Connecticut
  • Constitution State
  • Nutmeg State
  • Charter Oak State
 Delaware
 District of Columbia
 Florida
  • Alligator State[25]
  • Citrus State[citation needed]
  • Everglade State[25]
  • Flower State[25]
  • God's Waiting Room
  • Gulf State[25]
  • Hurricane State[citation needed]
  • La Florida
  • Manatee State[citation needed]
  • Orange State[25]
  • Peninsula State or Peninsular State[23]
  • Sunshine State (currently used on license plates)
  • Tropical State[Full Article

    technique

    The Game Changing Techniques of Internet Marketing Services

    Internet marketing is a frantic venture. Even after going through all the articles on internet marketing, it is not easy to keep up with it. Getting into this business, calls for dedication, tons of hours and plenty of research. It is not only frantic at times, but also competitive which means you must make up […]




    technique

    Empathy in Action: Techniques to Strengthen Relationships and Well-being

    Empathy is one of those quiet superpowers that can reshape our lives for the better. It isn’t flashy, but it has an impact everywhere—from our closest relationships to the way we interact at work, and even how we perceive our broader society. For example, consider a parent who takes the time to understand their child’s ... Read more

    The post Empathy in Action: Techniques to Strengthen Relationships and Well-being appeared first on LifeHack.




    technique

    5 Most Common Malware Techniques in 2024

    Tactics, techniques, and procedures (TTPs) form the foundation of modern defense strategies. Unlike indicators of compromise (IOCs), TTPs are more stable, making them a reliable way to identify specific cyber threats. Here are some of the most commonly used techniques, according to ANY.RUN's Q3 2024 report on malware trends, complete with real-world examples. Disabling of Windows Event Logging




    technique

    This Technique Allows Chronic Worriers To Think More Clearly

    A simple 8-minute exercise can free up your brain and make you more efficient under stress.



    • Boost Brain Power

    technique

    Persuasion: 10 Techniques Psychologists Recommend To Influence Anyone (P)

    Many people overthink persuasion, when it is the most natural approaches that work best.




    technique

    Introduction to Techniques Used to Study Mosquito Neuroanatomy and Neural Circuitry

    Mosquitoes transmit deadly pathogens from person to person as they obtain the blood meal that is essential for their life cycle. Female mosquitoes of many species are unable to reproduce without consuming protein that they obtain from blood. This developmental stage makes them highly efficient disease vectors of deadly pathogens. They can transmit pathogens between members of the same species and different species that can provide a route for evolving zoonotic viruses to jump from animals to humans. One possible way to develop novel strategies to combat pathogen transmission by mosquitoes is to study the sensory systems that drive mosquito reproductive behaviors, in particular the neural architecture and circuits of mosquito sensory afferent neurons, the central circuits that process sensory information, and the downstream circuits that drive reproductive behaviors. The study of mosquito neuroanatomy and circuitry also benefits basic neuroscience, allowing for comparative neuroanatomy in insect species, which has great value in the current model species-heavy landscape of neuroscience. Here, we introduce two important techniques that are used to study neuroanatomy and neural circuitry—namely, immunofluorescent labeling and neural tracing. We describe how to apply these approaches to study mosquito neuroanatomy and describe considerations for researchers using the techniques.




    technique

    New technique allows technicolor imaging of degenerative joint disease

    Medical imaging is no longer in Kansas, Toto, as a team led by Penn State researchers brings traditional black and white diagnostic images of X-rays and traditional CT scans into technicolor. The researchers developed novel contrast agents that target two proteins implicated in osteoarthritis, a degenerative joint disease commonly characterized as wear-and-tear arthritis.




    technique

    McMaster Technique Offers Delaware Livestock Producers and Veterinarians More Options in Herd Health

    he Delaware Department of Agriculture (DDA) announced beginning October 15, 2024, the cost of fecal analysis testing performed by the Poultry and Animal Health Section will increase to $3.00 per sample. The Poultry and Animal Health Section will begin offering livestock fecal sample analysis using the McMaster technique for relevant livestock species, and the current qualitative fecal float testing will still be performed as appropriate by species.





    technique

    BoardSurfers: Training Insights: What’s New in the Allegro PCB Editor Basic Techniques Course

    The Allegro PCB Editor Basic Techniques course provides all the essential training required to start working with Allegro® PCB Editor. The course covers all the design tasks, including padstack and symbol creation, logic import, constraints setup...(read more)




    technique

    Qigong Meditation for Beginners: Techniques, Benefits, and More

    Title: Qigong Meditation for Beginners: Techniques, Benefits, and More
    Category: Health and Living
    Created: 8/24/2022 12:00:00 AM
    Last Editorial Review: 8/24/2022 12:00:00 AM




    technique

    Breathing techniques to reduce symptoms in people with serious respiratory illness: a systematic review

    Background

    In adults with serious respiratory illness, breathlessness is prevalent and associated with reduced health-related quality of life. The aim of this review was to assess the impact of breathing techniques on breathlessness in adults with serious respiratory illness.

    Methods

    Electronic databases were searched to identify randomised controlled trials testing breathing techniques (techniques that aim to alter the respiratory pattern, excluding respiratory muscle training) in people with serious respiratory illness. The primary outcome was breathlessness and secondary outcomes were health-related quality of life and adverse events. Two authors independently screened for inclusion, evaluated risk of bias and extracted data.

    Results

    73 randomised controlled trials were included with 5479 participants, most with COPD or asthma. Breathing exercises (pursed lip and/or diaphragmatic breathing) reduced breathlessness measured by the modified Medical Research Council scale compared to usual care (mean difference (MD) –0.40 points, 95% CI –0.70– –0.11, eight studies, n=323), although the effect did not exceed the minimal important difference. Yoga breathing also improved modified Medical Research Council score compared to usual care (MD –1.05 points, 95% CI –2.45–0.35, three studies, n=175). Breathing techniques consistently improved health-related quality of life in people with COPD and asthma on multiple health-related quality of life measures in comparison to usual care, with effects that generally exceeded the minimal important difference. No adverse events related to breathing techniques were reported.

    Conclusion

    Breathing techniques may improve breathlessness, and consistently improve health-related quality of life, in people with serious respiratory illness. These findings support the use of breathing exercises in the care of people with serious respiratory illness.




    technique

    Comparison of Needle Depth Techniques for the Posterior Superior Alveolar Block

    Purpose The posterior superior alveolar (PSA) block injection is one of many techniques used to provide profound anesthesia for invasive dental procedures. This technique has a high success rate but is not without complication risks. The purpose of this study was to determine if pulpal anesthesia of the maxillary second molar could be achieved using a reduced needle depth of 10mm or 5mm compared to the traditional needle depth of 16mm.Methods Sixty participants were asked to participate in three sessions. Each session started with a pre neural response test, followed by one randomized needle depth PSA injection, and ending with a post neural response test. The neural response test consisted of two parts, a cold refrigerant and a dental probe, on the buccal and interproximal surface of the maxillary second molar. After receiving a positive neural response, each participant received a posterior superior alveolar block injection using a short (21mm), 27-gauge dental needle with a randomized needle penetration depth of 16mm, 10mm, or 5mm. A post neural response test consisting of the same two parts as the pre-test was conducted on the maxillary second molar to evaluate for profound anesthesia.Results Positive neural responses were obtained from 100% of the participants (n=167) during the pre-tests. Study results demonstrated an 85% success rate at the traditional 16mm needle depth and a 93% and 92% success rates for the reduced needle depths of 10mm and 5mm, respectively. Pulpal anesthesia of the maxillary second molar had been achieved at all three needle depths with no statistically significant difference in the rate of success. Furthermore, there were no adverse events observed.Conclusion The reduced needle depth technique showed promise in achieving desired results of pulpal anesthesia with a reduced risk for complications associated with the PSA block injection. Additional studies are recommended to achieve evidence-based support for this reduced needle depth technique.




    technique

    Stent Retriever AssIsted Lysis Technique with Tirofiban: A Potential Bailout Alternative to Angioplasty and Stenting [CLINICAL PRACTICE]

    BACKGROUND AND PURPOSE:

    Angioplasty and stent placement have been described as a bailout technique in individuals with failed thrombectomy. We aimed to investigate Stent retriever AssIsted Lysis (SAIL) with tirofiban before angioplasty and stent placement.

    MATERIALS AND METHODS:

    Patients from 2 comprehensive stroke centers were reviewed (2020–2023). We included patients with failed thrombectomy and/or underlying intracranial stenosis who received SAIL with tirofiban before the intended angioplasty and stent placement. SAIL consisted of deploying a stent retriever through the occluding lesion to create a bypass channel and infuse 10 mL of tirofiban for 10 minutes either intra-arterially or IV. The stent retriever was re-sheathed before retrieval. The primary end points were successful reperfusion (expanded TICI 2b–3) and symptomatic intracerebral hemorrhage. Additional end points included 90-day mRS 0–2 and mortality.

    RESULTS:

    After a median of 3 (interquartile range, 2–4) passes, 44 patients received the SAIL bridging protocol with tirofiban, and later they were considered potential candidates for angioplasty and stent placement bailout (43.2%, intra-arterial SAIL). Post-SAIL successful reperfusion was obtained in 79.5%. A notable residual stenosis (>50%) after successful SAIL was observed in 45.7%. No significant differences were detected according to post-SAIL: successful reperfusion (intra-arterial SAIL, 80.0% versus IV-SAIL, 78.9%; P = .932), significant stenosis (33.3% versus 55.0%; P = .203), early symptomatic re-occlusion (0% versus 8.0%; P = .207), or symptomatic intracerebral hemorrhage (5.3% versus 8.0%; P = .721). Rescue angioplasty and stent placement were finally performed in 15 (34.1%) patients (intra-arterial SAIL 21.0% versus IV-SAIL 44%; P = .112). At 90 days, mRS 0–2 (intra-arterial SAIL 50.0% versus IV-SAIL 43.5%; P = .086) and mortality (26.3% versus 12.0%; P = .223) were also similar.

    CONCLUSIONS:

    In patients with stroke in which angioplasty and stent placement are considered, SAIL with tirofiban, either intra-arterial or IV, seems to safely induce sustained recanalization, offering a potential alternative to definitive angioplasty and stent placement.




    technique

    Optimal Endovascular Therapy Technique for Isolated Intracranial Atherothrombotic Stroke-Related Large-Vessel Occlusion in the Acute-to-Subacute Stage [CLINICAL PRACTICE]

    BACKGROUND AND PURPOSE:

    Reocclusion after treatment is a concern in endovascular therapy for isolated intracranial atherothrombotic stroke-related large-vessel occlusion (AT-LVO). However, the optimal endovascular therapy technique for AT-LVO has not yet been investigated. This study evaluated the optimal endovascular therapy technique for AT-LVO in a real-world setting.

    MATERIALS AND METHODS:

    We conducted a historical, multicenter registry study at 51 centers that enrolled patients with AT-LVO. We divided the patients into 3 groups based on the endovascular therapy technique: mechanical thrombectomy alone, percutaneous transluminal angioplasty (PTA), and stent deployment. Mechanical thrombectomy alone was classified into the mechanical thrombectomy-only group; PTA and mechanical thrombectomy–PTA, into the PTA group; and mechanical thrombectomy–stent deployment, mechanical thrombectomy–PTA–stent deployment, PTA–stent deployment, and stent deployment–only into the stent group. The primary outcome was incidence of reocclusion of the treated vessels within 90 days of endovascular therapy completion.

    RESULTS:

    We enrolled 770 patients and analyzed 509 patients. The rates in the mechanical thrombectomy-only, PTA, and stent deployment groups were 40.7%, 44.4%, and 14.9%, respectively. Incidence rate of residual stenosis >70% of final angiography was significantly higher in the mechanical thrombectomy-only group than in the PTA and stent deployment groups (mechanical thrombectomy-only versus PTA versus stent deployment: 34.5% versus 26.3% versus 13.2%, P = .002). Reocclusion rate was significantly lower in the PTA group than in the mechanical thrombectomy-only group (adjusted hazard ratio, 0.48; 95% CI, 0.29–0.80). Of the patients, 83.5% experienced reocclusion within 10 days after endovascular therapy. Alarmingly, a substantial subset (approximately 62.0%) of patients experienced reocclusion within 2 days of endovascular therapy. Incidence of mRS scores of 0–2 ninety days after endovascular therapy was not significantly different among the 3 groups. Incidences of symptomatic intracranial hemorrhage, any other intracranial hemorrhage, and death were not significantly different.

    CONCLUSIONS:

    Incidence rate of reocclusion was significantly lower in the PTA group than in the mechanical thrombectomy-only group. We found no meaningful difference in reocclusion rates between the stent deployment and mechanical thrombectomy-only groups. In Japan, glycoprotein IIb/IIIa inhibitors are not reimbursed. Therefore, PTA might be the preferred choice for AT-LVOs due to the higher reocclusion risk with mechanical thrombectomy-only. Reocclusion was likely to occur within 10 days, particularly within 2 days post-endovascular therapy.




    technique

    Nobel prize for physics goes to pair who invented key AI techniques

    The 2024 Nobel prize in physics has gone to John Hopfield and Geoffrey Hinton for discoveries that enabled machine learning and are key to the development of artificial intelligence models like ChatGPT




    technique

    15,800-Year-Old Engraved Plaquettes Shed Light on Paleolithic Fishing Techniques

    Scientists from the Leibniz Zentrum für Archäologie and Durham University have examined a collection of 406 engraved schist plaquettes found at the Magdalenian site of Gönnersdorf in Germany.

    The post 15,800-Year-Old Engraved Plaquettes Shed Light on Paleolithic Fishing Techniques appeared first on Sci.News: Breaking Science News.




    technique

    Maximising Online Visibility and SEO for Restaurants: Tips and Techniques

    In the bustling world of the restaurant industry, standing out is more challenging than ever. With diners increasingly turning to the internet to discover their next meal, having a strong online presence is crucial. This guide will show you practical tips and techniques to maximise your restaurant’s online visibility and enhance your SEO efforts. By […]

    The post Maximising Online Visibility and SEO for Restaurants: Tips and Techniques appeared first on Chart Attack.




    technique

    Gene Signature Technique Boosts Survival in Breast Cancer

    Using a gene signature technique to customize chemotherapy for patients with early triple negative breast cancer may be a promising strategy to increase disease-free survival.





    technique

    More Transplants Possible: Study Offers Hope With New Technique

    In the United States, around 30-40% of potential donor hearts are excluded from transplant consideration due to insufficient function. This limits available