Modeste, Previste Using Bezier Curve analysis in context of Expression Analysis., 2019 . In ICASSP. (In Press) [Conference paper]

With four Indian-Americans, including two women, elected to the US Congress, euphoric community members said that the unprecedented victory shows they have become part of the mainstream political landscape.

A recent survey conducted by TimesJobs suggests that recruiters are never interested in a CV longer than two pages. The survey also reveals that about 43 pct pinpoints the importance of a CV’s length.

Writing a perfect CV is the road to your dream job. Poorly crafted curriculum vitae might ruin your first impression in front of the HR team. Take a look at these tips that can help you to write an impressive CV.

TikTok star Nagma Mirajkar has been doing rounds on the internet by coming up with many superb videos each day. From comedy to serious, the pretty lady has not an area left, where she can't entertain people with her talent

There are mixed feelings among executives about the idea, ranging from frustration to begrudging acceptance.

Filed under: Food and Drink, North America, United States

• Regardless of the area's suitability for growing grapes, plop down a vineyard or winery and travelers will come for a taste and buy a sympathy bottle (pro tip: go for the ice wine as it's harder to mess up)
• Ski resorts looking to attract off-season dollars or stale attractions looking to draw media coverage and visitors hook up a zipline

Continue reading Vineyard and Zipline Trends Collide at the Pinot Express

Vineyard and Zipline Trends Collide at the Pinot Express originally appeared on Gadling on Wed, 11 Dec 2013 16:54:00 EST. Please see our terms for use of feeds.

As Quebec begins to reopen schools and businesses, Prime Minister Justin Trudeau said he’s ‘worried’ about the province’s deconfinement plans, particularly in Montreal.

Bacterial products such as lipopolysaccharides (or endotoxin) cause systemic inflammation, resulting in a substantial global health burden. The onset, progression, and resolution of the inflammatory response to endotoxin are usually tightly controlled to avoid chronic inflammation. Members of the NF-κB family of transcription factors are key drivers of inflammation that activate sets of genes in response to inflammatory signals. Such responses are typically short-lived and can be suppressed by proteins that act post-translationally, such as the SOCS (suppressor of cytokine signaling) family. Less is known about direct transcriptional regulation of these responses, however. Here, using a combination of in vitro approaches and in vivo animal models, we show that endotoxin treatment induced expression of the well-characterized transcriptional repressor Krüppel-like factor 3 (KLF3), which, in turn, directly repressed the expression of the NF-κB family member RELA/p65. We also observed that KLF3-deficient mice were hypersensitive to endotoxin and exhibited elevated levels of circulating Ly6C+ monocytes and macrophage-derived inflammatory cytokines. These findings reveal that KLF3 is a fundamental suppressor that operates as a feedback inhibitor of RELA/p65 and may be important in facilitating the resolution of inflammation.

Prevention of aberrant cutaneous wound repair and appropriate regeneration of an intact and functional integument require the coordinated timing of fibroblast and keratinocyte migration. Here, we identified a mechanism whereby opposing cell-specific motogenic functions of a multifunctional intracellular and extracellular protein, the receptor for hyaluronan-mediated motility (RHAMM), coordinates fibroblast and keratinocyte migration speed and ensures appropriate timing of excisional wound closure. We found that, unlike in WT mice, in Rhamm-null mice, keratinocyte migration initiates prematurely in the excisional wounds, resulting in wounds that have re-surfaced before the formation of normal granulation tissue, leading to a defective epidermal architecture. We also noted aberrant keratinocyte and fibroblast migration in the Rhamm-null mice, indicating that RHAMM suppresses keratinocyte motility but increases fibroblast motility. This cell context–dependent effect resulted from cell-specific regulation of extracellular signal-regulated kinase 1/2 (ERK1/2) activation and expression of a RHAMM target gene encoding matrix metalloprotease 9 (MMP-9). In fibroblasts, RHAMM promoted ERK1/2 activation and MMP-9 expression, whereas in keratinocytes, RHAMM suppressed these activities. In keratinocytes, loss of RHAMM function or expression promoted epidermal growth factor receptor–regulated MMP-9 expression via ERK1/2, which resulted in cleavage of the ectodomain of the RHAMM partner protein CD44 and thereby increased keratinocyte motility. These results identify RHAMM as a key factor that integrates the timing of wound repair by controlling cell migration.

'Destination Wedding' book review: The land of contradictions  The New Indian Express

OM Belgium and OM Arts creatively connect with the local community through drawings, song, poetry and flowers.

There's nothing out there in the market today like the Maruti Suzuki S-Presso so we drove the automatic and manual versions of the car around Jodhpur to find out if it has what it takes to infuse some life into a declining segment and create a niche. 

The Maruti Suzuki S-Presso is decently roomy, has a good feature spread and at the same time is reasonably frugal at the pumps, micro-SUV.

Honda Amaze in its refreshed avatar is a much better looking car with improved features. However, unlike its rivals with cheaper AMTs, this one comes with a more expensive CVT. Is the Honda Amaze petrol CVT worth the extra money and how is it to drive? Read on.

The Micro-SUV segment is just starting to take shape with Maruti Suzuki now getting on board with the S-Presso. But Renault, the pioneers of the segment, have updated the Kwid with a facelift that makes the little hatchback/SUV a little fresher. We drive to find out if the new changes have what it takes to stand strong against the new kids on the block.

Indian cotton prices have come down by 12-15% due to the ongoing lockdown and fears that the country’s cotton consumption will reduce, resulting in more carry-forward stocks by September 2020, officials of the Cotton Association of India (CAI) said on Tuesday.

Moto G5 makes a good first impression with its high-end features

Banana accounts for as much as 60-65% of the green exports from Kerala and the rest are vegetables. Of the banana varieties, nenthran plantain leads the food preferences of Kerala’s 20 lakh diaspora families fanning out in the GCC countries.

Nearly 7,000 people have signed a change.org petition to open up courses in the UK as parks during the pandemic.

Chief Minister Pinarayi Vijayan has time and again sought to drive home the point that complacency cannot be afforded despite a seemingly better show.

Apps today are opening up channels of communication on several ‘uncomfortable’ topics. From sexual health and addictions to depression and mood tracking, help is just a click away.

Coronavirus numbers explained: New cases start dipping  The Indian Express

Many in China think academic pressure on children is out of hand but it is not clear a measure to deemphasize cramming will work.

Is it necessarily unlawful for an employer to dismiss an employee for incapability if she fails to return to work following the end of maternity leave, where the reason for the absence is post-natal depression (or other pregnancy-connected illness)?...

I've been using a Chromebook Pixel for the past two days and a single phrase comes to mind: blown away. Is it worth $1,299 or more? Take a look to see and then stack it up against your mobile computing needs.

The following are the top stories on the New York Times business pages. Reuters has not verified these stories and does not vouch for their accuracy.

Brazil's Economy Minister Paulo Guedes on Saturday said the country's central bank is likely to shower the economy with money in case of an economic depression.

Brazil's Economy Minister Paulo Guedes on Saturday said the country's central bank is likely to shower the economy with money in case of a depression due to the coronavirus pandemic.

Presumptive Democratic nominee Joe Biden’s campaign is beefing up its digital staff, just as it had been hit by a series of technical problems at a virtual event on Thursday -- and amid alarm bells from Democratic allies that it is lagging behind the Trump campaign on the digital battlefield.

World Password Day advice, GoDaddy hosting accounts hacked and WordPress sites under attack. Welcome to Cyber Security Today. It’s Wednesday May 6th. I’m Howard Solomon, contributing reporter on cybersecurity for ITWorldCanada.com. Tomorrow is World Password Day. So follow safe password practices so you don’t help criminals steal data. How bad are you? Here’s are few…

It's the first time Baldwin has impersonated the president in an episode of 'SNL at Home'

Jordan would hit .202 that season in Class AA Birmingham with 114 strikeouts (most on the team), 51 RBIs (fourth) and 30 stolen bases (second). But former colleagues are still in awe when reminiscing about MJ’s competitive spirit and stage presence.

With the new NRL season set to re-launch in 20 days Fox League takes a look at the pressure point issues guaranteed to make headlines once the football returns.

The catastrophic impact of COVID-19 on long-term care facilities likely was exacerbated by the outdated design and crowded conditions found in some seniors’ homes, experts say.

How talented is Jamie Foxx? Talented enough to smoothly slip in and out of his Jay-Z, Dave Chappelle and Mike Tyson impressions ... without skipping a beat. The actor/singer/comedian/all-around-renaissance-man broke down the most famous, and…