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METHODS AND COMPOSITIONS RELATING TO FUSIONS OF ALK FOR DIAGNOSING AND TREATING CANCER

Disclosed are methods and compositions for detecting the presence of a cancer in a subject and assessing the efficacy of treatments for the same. The disclosed method use reverse transcription polymerase chain reaction (RT-PCR) and multiplex polymerase chain reaction techniques as well as Template Exchange Extension Reaction (TEER) to detect the presence of point mutations, truncations, or fusions of anaplastic lymphoma kinase.




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ARTICULATING VACUUM PLATE SYSTEM AND RELATED METHOD

An apparatus and related method of utilizing articulating vacuum plates to manipulate a film or polymeric sheet and form a three dimensional article is provided. The apparatus can be in the form of an articulating vacuum plate system which includes one or more plates or mold parts that are configured to support a sheet, constructed for example, from a polymeric film, in a two dimensional configuration or a three dimensional configuration in a first mode. The apparatus is constructed so that the plates and/or mold parts can articulate or move so as to reconfigure the sheet from a generally planar configuration into a second three dimensional configuration in a second mode for further forming, optionally while the plates and/or mold parts apply vacuum to the sheet while the plates and/or mold parts articulate, so that the plates and/or mold parts bend or otherwise manipulate the configuration and shape of the sheet.




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Tumbao Bravo: Latin Jazz - Just Perfect On Cinco De Mayo For 5:01 Jazz!

On May 5th – Cinco de Mayo – WEMU wraps up the 2017 winter/spring Sesi Motors 5:01 Jazz shows with a real showstopper – the magnificent Latin jazz group, Tumbao Bravo . While Paul Vornhagen continues to head up Tumbao Bravo on saxophone, flute, piccolo and percussion, he has added new members and new repertoire while retaining tunes of years past and some veteran players. Joining Paul for “5:01 Jazz” are Olman Piedra – timbales, Brian DiBlassio – keyboards, Gregory (Greco) Freeman – congas and, Joe Fee – bass.




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Andrew Garfield Finds Life 'Very Strange' as He's Self-Isolating Alone Amid Pandemic

The 'Amazing Spider-Man' actor shares tips on how to deal with stress as he is quarantining by himself during the ongoing lockdown amid coronavirus pandemic.




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Andrew Garfield Finds Life 'Very Strange' as He's Self-Isolating Alone Amid Pandemic

The 'Amazing Spider-Man' actor shares tips on how to deal with stress as he is quarantining by himself during the ongoing lockdown amid coronavirus pandemic.




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Ueberschall launches Multitrack Drum Loop Series Vol. 3: Latin Brasil Beats

Ueberschall has announced the release of Latin Brasil Beats, a new title in the Multitrack Drum Loop Series which provides the authentic vibrance and groove of Latin rhythms. The library is built from 10 GB of sample data and contains more than 3,800 individual loops divided into sixteen performance-based folders. Each folder features multiple parts […]

The post Ueberschall launches Multitrack Drum Loop Series Vol. 3: Latin Brasil Beats appeared first on rekkerd.org.




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More Than 90% of Self-Isolating Families Have at Least One OTT Service

New survey data from Hub Entertainment Research reveals the impact of COVID-19 on OTT services and pay TV




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Indian Police Force Tourists Violating Lockdown To Write 'I Am Very Sorry' 500 Times

Indian police have the unenviable task of enforcing the world's biggest coronavirus lockdown . But last weekend, they handed down a punishment more common in a middle-school classroom than a police station. Ten foreign tourists caught flouting India's coronavirus restrictions Saturday were made to write the phrase "I did not follow the rules of lockdown. I am very sorry" 500 times and submit the paper to police. The incident happened at a sandy beach along the Ganges River near Rishikesh, a tourist hub in northern India famous for yoga retreats and hippie hangouts. It's where the Beatles made a spiritual pilgrimage in 1968. An officer who answered the phone Monday at the Muni Ki Reti police station near Rishikesh confirmed details to NPR, but declined an interview. The tourists were reportedly from Israel, Mexico, Australia and Austria, and were walking along the river when Indian police intervened. Under India's lockdown, all nonessential outings are banned. Video shared online by




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JYP Entertainment Seeking Quality Songs for Platinum Selling Male & Female K-Pop Artists

Hey, I'm an in-house producer for JYP Entertainment, the largest Kpop label in South Korea. We're looking for songs to place with both our male and female artists. Please only send your best songs complete with a beat, vocals, and lyrics. Genre's we are looking for include, but not limited to,: Pop, Dance, Electronic, R&B, Soul, Ballad, Hip Hop, Urban. Good luck!

JYP Entertainment is a South Korean entertainment company that operates as a record label, talent agency, music production company, event management and concert production company, and music publishing house. JYP Entertainment is currently the home of artists including 2PM, Miss A, Baek A-yeon, 15&, JJ Project, Got7, Nakjoon, Day6, Twice, and Jeon So-mi, and formerly to artists like Park Ji-yoon, g.o.d, Rain, Jay Park, San E, Meng Jia, Wonder Girls, Sunmi, Ha:tfelt, and 2AM.

- Tommy Park / JYP Entertainment




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Platinum-Selling Songwriter Jimmy Webb On The Stories Behind His Biggest Hits

Platinum-selling songwriter Jimmy Webb stopped by our studio last October to talk about his first memoir, " The Cake And The Rain ." Artists from Frank Sinatra to Barbara Streisand have recorded Webb's songs. Some of his hits include “Up, Up and Away,” “Wichita Lineman,” “MacArthur Park,” and “By The Time I Get to Phoenix.” Our conversation begins with a discussion of his childhood in rural Elk City, Oklahoma. He explains how his mother’s “iron will and sometimes anger” drove him to the piano. Plus, Webb talks about the time he was out plowing a field when a voice on the radio captivated him. It belonged to Glen Campbell , who became a close collaborator of Webb’s. He reveals the story behind his celebrated classic "By The Time I Get To Phoenix," for which Campbell won two Grammy awards. Webb also talks about his hit "Wichita Lineman," another song that Campbell recorded. Once, at the Songwriters Hall of Fame , Billy Joel described “Wichita Lineman” as being “emblematic of an ordinary




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Muralist Daniel DeSiga celebrated Latino culture and heritage through art


One of Daniel DeSiga’s most famous murals, “Explosion of Chicano Creativity,” greets visitors at Seattle's El Centro de la Raza.




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Mariners’ Manny Acta remains mindful of Latin minor-leaguers’ plight amid coronavirus outbreak


Acta spoke candidly is issues in Dominican Republic and MLB players complaining about the proposed restart plan.




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Mariners’ Manny Acta remains mindful of Latin minor-leaguers’ plight amid coronavirus outbreak


Acta spoke candidly is issues in Dominican Republic and MLB players complaining about the proposed restart plan.




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What Would A Sharp Decline In Remittances Mean For Latin America

Immigrants in the U.S. sent an estimated $150 billion to their home countries in 2019 — half to Latin America and the Caribbean. The World Bank is predicting a sharp decline in remittances this year.




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No One Should Be Jailed For Violating Executive Order: Texas Governor

Texas Governor Greg Abbott issued an executive order saying that in the state of Texas, no one can be put behind bars because they're not following an executive order. This was announced by the governor himself while speaking with reporters in the Oval Office after a meeting with President Donald Trump. The Republican Governor met with the President Thursday to discuss Texas' response to the co




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COVID-19 and nursing homes, China's state surveillance, the political Dr. Seuss, repopulating Fukushima & more

Canadian nursing homes look to Washington State for lessons about COVID-19, public health vs. surveillance in China's battle against the coronavirus, the Jewish-Palestinian lesbian couple who mine their relationship for comedy gold, the Japanese government's plan to repopulate Fukushima, Dr. Seuss' complicated history as a political cartoonist and more.



  • Radio/Day 6

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'Truly surreal': Isolating on an abandoned ski mountain in Canada

When the COVID-19 restrictions hit Big White in British Columbia, Canada, 90 per cent of the mountain dwellers left within 24 hours, leaving behind hundreds of dollars worth of ski equipment and even abandoning their cars in the street.




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Counterfeit $100 notes circulating in Riverland trigger police warning about fake money

Businesses in SA's Riverland are urged to be on the lookout for fake $100 notes after one was passed at a bakery and two other incidents were reported to police.





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Prickles returns home ready to be shorn after seven years self-isolating

Prickles the merino sheep has been on the run from her Dunalley farm since the 2013 Tasmanian bushfires, but now she's out of self-isolation and ready for a trim.




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Queensland bushfire threat rises as homes lost in escalating Sunshine Coast emergency situation

Alarming footage shows high winds driving a large bushfire overnight on the Sunshine Coast, where 10 homes have been lost at Peregian Springs and Peregian Beach.




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Man who tackled 'Eggboy' has outstanding warrant on charges relating to church incident

A far-right activist who restrained a teenager after he egged Senator Fraser Anning is wanted by police on charges of disturbing a place of religious worship.




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Jenni Rivera Enterprises v. Latin World Entertainment etc

(California Court of Appeal) - Reversed order denying Defendant’s motion to strike. Plaintiff represented deceased celebrity, Jenni Rivera, and they sought to restrict disclosure by Defendant broadcaster of certain information. Appeals court ruled the First Amendment protected broadcaster’s use of information and reversed trial court order.




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Watch: 10 incredible trick shots from self-isolating golfers




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League of United Latin American Citizens v. Edwards Aquifer Authority

(United States Fifth Circuit) - Affirmed. A conservation and reclamation district regulating groundwater was not subject to the one person, one vote principle of the Equal Protection Clause because they are a special purpose unit of the government. Its apportionment scheme had a rational basis.




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League of United Latin American Citizens v. Edwards Aquifer Authority

(United States Fifth Circuit) - Affirmed. A conservation and reclamation district regulating groundwater was not subject to the one person, one vote principle of the Equal Protection Clause because they are a special purpose unit of the government. Its apportionment scheme had a rational basis.




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Bay Area Reggae/Latin Powerhouse BAYONICS Sets Worldwide Release Of Their Highly Anticipated New Album RESILIENCE

BAYONICS Will Release Their New Album RESILIENCE In Stores And Online August 2, 2019.




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Cap Hill hippie haven Sancho’s Broken Arrow cited for violating stay-at-home order

Capitol Hill bar Sancho's Broken Arrow has received a notice from the city requiring it to be vacated immediately and remain empty until the city's stay-at-home order is lifted.




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After an “American Dirt” event in Denver was canceled, Latinx writers were invited to host their own reading

After strong backlash to author Jeanine Cummins' controversial new novel "American Dirt," the book's publisher canceled Cummins' remaining tour dates, including a Feb. 2 event at Tattered Cover in Denver, citing safety concerns. Before learning of the event's cancellation, Latinx writers in Denver were planning to host a protest reading in… Read more »




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Colorado Latinos grapple with increased risk of coronavirus infections

“We’re just really scared and there's no protections and there's no testing, and we’re just continually exposed.”




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NYPD Caught Punching Man For Violating Social Distance Order



The enforcement was meant to protect from coronavirus spread




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NYPD Caught Punching Man For Violating Social Distance Order



The enforcement was meant to protect from coronavirus spread




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BPS: Message Circulating Is Not For Bermuda

The fake social media message warning residents about a group of individuals allegedly pretending to verify data for a Government census but really planning to steal from homes is circulating again, leading the police to issue another advisory. The police — who have advised before that this message does not pertain to Bermuda — said, […]

(Click to read the full article)




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Court: Two Men Deny Charge Relating To Video

[Written by Don Burgess] Appearing in Magistrates Court today, Ezra Ararat, 34, of Devonshire, and Raymond Swan, 44, of Hamilton parish, pleaded not guilty to a charge related to allegedly threatening law enforcement officials by publishing a video advocating the shooting of police, prosecutors, and judges. Mr Ararat was remanded into custody by Senior Magistrate […]

(Click to read the full article)




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Legal Issues Relating to Airports Promoting Competition

The TRB' Airport Cooperative Research Program's ACRP LRD 37: Legal Issues Relating to Airports Promoting Competition explores permissible means and methods of encouraging and accommodating competition at U.S. airports. It discusses the history of how competition has been addressed by government and airports and provides the context of the concentration of air carriers and fixed-base operators (FBOs), the accommodation of air carriers with differing business models, and avoiding the grant of exclusive rig...



  • http://www.trb.org/Resource.ashx?sn=cover_acrplrd37

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Myeloid-specific Asxl2 deletion limits diet-induced obesity by regulating energy expenditure

We previously established that global deletion of the enhancer of trithorax and polycomb (ETP) gene, Asxl2, prevents weight gain. Because proinflammatory macrophages recruited to adipose tissue are central to the metabolic complications of obesity, we explored the role of ASXL2 in myeloid lineage cells. Unexpectedly, mice without Asxl2 only in myeloid cells (Asxl2ΔLysM) were completely resistant to diet-induced weight gain and metabolically normal despite increased food intake, comparable activity, and equivalent fecal fat. Asxl2ΔLysM mice resisted HFD-induced adipose tissue macrophage infiltration and inflammatory cytokine gene expression. Energy expenditure and brown adipose tissue metabolism in Asxl2ΔLysM mice were protected from the suppressive effects of HFD, a phenomenon associated with relatively increased catecholamines likely due to their suppressed degradation by macrophages. White adipose tissue of HFD-fed Asxl2ΔLysM mice also exhibited none of the pathological remodeling extant in their control counterparts. Suppression of macrophage Asxl2 expression, via nanoparticle-based siRNA delivery, prevented HFD-induced obesity. Thus, ASXL2 controlled the response of macrophages to dietary factors to regulate metabolic homeostasis, suggesting modulation of the cells’ inflammatory phenotype may impact obesity and its complications.




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Banorte - Ixe se asocia con IBM para establecer un modelo único de banca en América Latina, con enfoque total al cliente.

• Con vigencia de 10 años, Banorte e IBM firman alianza estratégica que permitirá establecer las bases de un nuevo modelo de banca enfocado al cliente, y mejorar sustancialmente sus índices de eficiencia para alcanzar niveles cercanos al 40%, así como retornos sobre capital superiores al 20%. El acuerdo incluye servicios de consultoría y de tecnología, investigación y desarrollo. • “Estamos plenamente satisfechos con el acuerdo logrado, pues este suma el mejor talento humano, tanto de IBM, como de Banorte Ixe, y está en línea con nuestra búsqueda de herramientas tecnológicas para servir a nuestros clientes de manera individualizada”: Alejandro Valenzuela.



  • Banking and Financial Services

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BBVA lidera la transformación tecnológica de la banca en Latinoamérica y EE.UU. de la mano de IBM

El Grupo BBVA acaba de formalizar un acuerdo con IBM para que esta firma asuma la operación y transformación de la infraestructura tecnológica actual de BBVA y el procesamiento de datos en América Latina y EE.UU., actualmente gestionada por su filial ATA en México.



  • Global Technology Services

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La infraestructura de IBM ayuda a empresas de Latinoamérica a mejorar resultados con tecnologías de nube, analítica, movilidad y social

Empresas y organizaciones como bancos, agencias de viajes, restaurantes, proveedores de salud y gobiernos municipales en toda América Latina están adoptando nuevas tecnologías de nube, movilidad y analítica que llevan a una mayor eficiencia, menores costos y un mejor servicio a sus clientes y ciudadanos.




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IBM contribuye a la reinvención de la fuerza de trabajo en América Latina, beneficiando a más de 370.000 estudiantes con acceso a conocimiento en IA, Cloud y Blockchain

IBM (NYSE: IBM) anunció hoy que está trabajando con más de 300 universidades y más de 400 instituciones educativas en toda Latinoamérica para respaldar la inminente necesidad de desarrollar habilidades asociadas a los requerimientos de la transformación digital, ya que el 60% de los ejecutivos se esfuerza hoy por mantener las habilidades de la fuerza laboral actualizadas y relevantes frente al rápido avance tecnológico.




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IBM anuncia nueva gerente general en América Latina

IBM anunció hoy que Ana Paula Assis ha sido nombrada gerente general para IBM América Latina. Ana Paula será responsable por la estrategia de negocios de la compañía y el desarrrollo de sus profesionales, y trabajará con los clientes y el mercado para ayudar a acelerar la transformación digital y la adopción de inteligencia artificial y nuevos modelos cognitivos en la región.




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Delta SkyMiles® Platinum American Express Card Review

An attractive rewards credit card for frequent Delta flyers. While some American Express rewards cards offer great perks, like complimentary access to its exclusive network of airport lounges, you won’t get that perk with the (lounge access costs $39 per visit). However, you will get attractive rewards rates on several types of travel-related purchases along with other valuable travel benefits. This card offers you the highest reward rate when you make purchases with Delta or spend on hotel bookings, which […]

The post Delta SkyMiles® Platinum American Express Card Review appeared first on The Simple Dollar.




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Even the strays are isolating




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How Can I Really Market One of These Platinum YourNetBiz Opportunity Packages?

So you now have a YourNetBiz Opportunity. You have invested your money and you have setup your website. Now what? Well the good news is you are in the right place my friend. This article will explain how you can focus your efforts and market the right way.




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Latin Men

To be honest I didn39t think I would still be here in Buenos Aires one month into my trip. Last night Sally and I planned some of our travel which made it all a reality and pretty exciting. We went out after as well and we get on very well. It looks




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For Latinos and COVID-19, doctors are seeing an ‘alarming’ disparity




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Chris Cornell’s widow fires back at Soundgarden members in escalating legal war, says they’re tying to ‘browbeat’ her into giving up music

Chris Cornell’s widow is firing back at her husband’s Soundgarden bandmates, calling the lawsuit they filed against her Wednesday an attempt to “browbeat” her into giving up “copyrighted works.”




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Manslaughter arrest for woman accused of fatally striking NYC hospital patient for violating coronavirus social distancing

Hospital police initially issued Lundy a disorderly conduct summons after the attack and released her. On Thursday NYPD cops arrested her for manslaughter and assault.




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Black and Latino students admitted to NYC’s specialized high schools stays flat at 11%

At Stuyvesant High School in Manhattan, the city’s most selective public high school, only 10 black students and 20 Latino students got admissions offers, out of nearly 800 students accepted, data shows.




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NYC lawmakers push to expand specialized high school exam to combat low black, Latino enrollment

The proposal comes as city officials announced that only 11% of students admitted to specialized schools this year were black or Latino, compared to 70% of all city students, a figure virtually unchanged from years past.