latin El Eterno Tour 2022 de Manuel Medrano llega a América Latina By www.spreaker.com Published On :: Wed, 26 Oct 2022 17:53:00 +0000 Full Article
latin ‘Los reyes de la salsa choke’, trabajo con el que Cali Flow Latino celebra 10 años de carrera By www.spreaker.com Published On :: Tue, 27 Dec 2022 17:38:00 +0000 Full Article
latin 2.000 personas han ingresado en 4 años a la primera sala de consumo seguro de América Latina By www.spreaker.com Published On :: Tue, 13 Feb 2024 17:18:00 +0000 Las instalaciones de este lugar se encuentran en México y fueron consolidadas por la ONG Verter A.C. Full Article
latin Noel Schajris se convierte en el primer artista latino en lanzar su propia app By www.spreaker.com Published On :: Thu, 07 Mar 2024 18:14:00 +0000 Full Article
latin Thomas Shannon, diplomático estadounidense en retiro experto en Latinoamérica By www.spreaker.com Published On :: Thu, 01 Aug 2024 18:56:00 +0000 Full Article
latin El mayor proyecto de incentivo a la lectura de América Latina llega a Colombia By www.spreaker.com Published On :: Sun, 29 Aug 2021 21:26:00 +0000 Full Article
latin Mario Alcalá en los Premios Platino de Cine Iberoamericano 2021 By www.spreaker.com Published On :: Sat, 02 Oct 2021 18:36:00 +0000 Full Article
latin Continúa el cubrimiento de los Premios Platino de Cine Iberoamericano By www.spreaker.com Published On :: Mon, 04 Oct 2021 02:08:00 +0000 Full Article
latin Federico Uribe, el artista oficial de los Latin Grammy 2021 By www.spreaker.com Published On :: Sat, 23 Oct 2021 17:12:00 +0000 Full Article
latin Colombia se hizo sentir en los Premios Grammy Latino 2021 By www.spreaker.com Published On :: Mon, 22 Nov 2021 01:31:00 +0000 Full Article
latin La edición en la actualidad en España, África y América Latina By www.spreaker.com Published On :: Tue, 01 Mar 2022 02:13:00 +0000 Full Article
latin Guho Cho, el traductor coreano de obras literarias latinoamericanas By www.spreaker.com Published On :: Sat, 30 Apr 2022 18:11:00 +0000 Full Article
latin Bogotá tendrá el primer ‘Bosque Sonoro’ en Latinoamérica By www.spreaker.com Published On :: Sat, 11 Jun 2022 16:02:00 +0000 Full Article
latin Comienza la etapa de donación en Latinoamérica para Wikipedia By www.spreaker.com Published On :: Sat, 11 Jun 2022 16:13:00 +0000 Full Article
latin El 20 de julio inicia la Feria Latinoamericana del libro de Cartagena de Indias By www.spreaker.com Published On :: Sun, 17 Jul 2022 17:18:00 +0000 Full Article
latin Medellín es la primera ciudad de Latinoamérica en estar en el Metaverso By www.spreaker.com Published On :: Sun, 31 Jul 2022 20:53:19 +0000 Medellín es la primera ciudad de Latinoamérica en estar en el Metaverso Full Article
latin Premios Latin Grammy: Claraluna y Chabuco son algunos de los artistas colombianos nominados By www.spreaker.com Published On :: Sun, 25 Sep 2022 15:40:00 +0000 Full Article
latin Natalia y Nicolás Ramírez: dos ingenieros de sonido colombianos nominados los Premios Latin Grammy By www.spreaker.com Published On :: Sun, 25 Sep 2022 16:42:00 +0000 Full Article
latin Shanna Fuentes, la colombiana que conecta y ayuda a toda la comunidad latina en Nueva York By www.spreaker.com Published On :: Mon, 14 Nov 2022 17:08:00 +0000 Full Article
latin Luis Sierra, el mejor divulgador de la ciencia de América Latina By www.spreaker.com Published On :: Sat, 08 Apr 2023 18:15:00 +0000 Full Article
latin Paula Arenas, la bogotana nominada a los premios Grammy Latinos By www.spreaker.com Published On :: Wed, 01 Nov 2023 20:56:00 +0000 Full Article
latin “Hezbolá representa un riesgo real para todos los países de Latinoamérica”: analista internacional By www.spreaker.com Published On :: Thu, 07 Mar 2024 13:33:00 +0000 Full Article
latin El trabajo de Juan Petro fue nulo en la comisión de Paz: Comisión Latinoamericana de DDHH By www.spreaker.com Published On :: Tue, 26 Mar 2024 15:29:00 +0000 En 6AM Hoy por Hoy, Rodrigo Ricaurte, director para América Latina de la Comisión Latinoamericana de DDHH, cuestiona el nombramiento de Juan Fernando Petro como Alto Comisionado de Paz, calificándolo como un “gravísimo error”. Full Article
latin “Colombia es el único país estable en América Latina gracias a su constitución”: Eloy García By www.spreaker.com Published On :: Wed, 03 Jul 2024 14:35:00 +0000 En 6AM hoy por Hoy, se conecta Eloy García, académico, jurista español, experto en “El Poder constituyente”. Full Article
latin AWARD / GRANT: Donald Vega Earns Grammy Nomination For 'As I Travel' - Best Latin Jazz Album By www.allaboutjazz.com Published On :: 2024-11-10T14:40:07+00:00 Celebrated pianist and composer Donald Vega receives a GRAMMY nomination in the category of Best Latin Jazz Album for his 2023 recording of As I Travel, an autobiographical suite of compositions inspired by his journey to the United States from his native Nicaragua, and the people and experiences that shaped him along the way.... Full Article
latin Say Uncle | Latin Leche: Rodrigo El Santo and Alexander Rajesh By www.queerclick.com Published On :: Wed, 13 Nov 2024 05:04:48 +0000 New on Latin Leche, a Say Uncle site: You are horny all day at your job and you just can’t wait to get home and fuck your main squeeze… and fuck they just want to argue, talk about blue balls! So, you head to the gym and after an intense session you enter the sauna….... View Article The post Say Uncle | Latin Leche: Rodrigo El Santo and Alexander Rajesh appeared first on QueerClick. Full Article Porn Site Updates Alexander Rajesh LatinLeche Rodrigo El Santo
latin FAFO: Latino Believes Trump Won't Deport Family-Oriented Migrants By crooksandliars.com Published On :: Wed, 13 Nov 2024 02:59:24 +0000 In today's edition of FAFO (F*ck Around and Find Out) we have a man who is probably going to learn the hard way that being one of the "good ones" means nothing to the Trump administration. See, MAGA loyalty only goes one way. They want your vote, but won't do anything to make your life better. This Latino male Trump voter told CNN that mass deportation won't extend to law-abiding workers. He actually said, with a straight face: “That wouldn’t be fair. They need to make sure that they don’t throw away, they don’t kick out, they don’t deport people that are family oriented.” Sweetie, they don't care if you are family oriented or not. If you are working a good job or not. If you are a criminal or not. To them, being non-American is enough to get you kicked out (and probably put in a camp before). Enjoy that Trump hair visor hat, honey. The leopards are coming for your face. "Fucketh around and ye shall findeth out" - A Twitter User in 2024 read more Full Article deportation FAFO Latino Leopards Eating Faces MAGA
latin How to get funding from deluded, self-congratulating investors By blog.penelopetrunk.com Published On :: Sun, 21 Apr 2024 05:37:04 +0000 From 1997 to 2012 just 1% of VC funded companies had female founders. Three of those companies were mine. People tell me it’s much better for women now, but statistically, this is BS. I raised money for a startup recently, and here’s what I found works best for female founders: Get a male cofounder. Women raising money without […] The post How to get funding from deluded, self-congratulating investors appeared first on Penelope Trunk Careers. Full Article Entrepreneurship
latin Nudaros, The Taste of Latin Music By www.star2.org Published On :: Sat, 21 Jan 2023 00:48:40 +0000 Today we will speak with Nudaros, an Iranian music artist who started her music career in Spain in Latin style and will continue to follow this path and seek new experiences after succeeding in this style. A.K: I want to start with your name; why Nudaros? Nudaros: The lexical abbreviation Nodarus goes back to nude, ... Read more The post Nudaros, The Taste of Latin Music appeared first on Star Two. Full Article Music Musician Iran Mojavez Iranian music artist Latin Music Nudaros
latin Say it ain’t so, Joe! Latino voters on Telemundo give President Trump the debate win 66% to 34% By powderedwigsociety.com Published On :: Thu, 01 Oct 2020 00:37:49 +0000 Suddenly, the Democratic Party is all about stopping illegal immigration. The post Say it ain’t so, Joe! Latino voters on Telemundo give President Trump the debate win 66% to 34% appeared first on Powdered Wig Society. Full Article 2020 presidential election telemundo
latin My Faith in Nerds: Stronger Than Any Gelatinous Cube By www.43folders.com Published On :: Fri, 10 Sep 2010 20:01:57 +0000 dConstruct 2010: Merlin Mann - "Kerning, Orgasms & Those Goddamned Japanese Toothpicks" (NSFW) ME - Kerning, Orgasms And Those Goddamned Japanese Toothpicks on Huffduffer Download the audio | Huffduff it Let's be honest. I don't go...mmmm...places very often. I sit in this chair. I go to the Safeway with my daughter. Sometimes, I take the train downtown to get a haircut. I check the mail. But, by and large, like most nerds, I'm without question, a bit of a shut-in. Which makes it more than a little ironic that my first trip off the North American continent brought me all the way to Brighton, England's wonderful dConstruct Conference. Which wonderful conference placed me inside a very royal complex, alone on a very large stage, 90 seconds after being informed I'd better be entertaining, because I'd be conducting my oration on the same spot where, a scant 36 years earlier, ABBA had become international stars by singing an up-tempo number about giving up. So, y'know. No pressure. Commanded to this location by two of my web heroes, I was told I could speak about whatever I wanted. So, wow, to quote the ladies of ABBA, how could I ever refuse? Thus, I stood on that stage for over 35 minutes, rambling to 800 talented, creative people about Dungeons & Dragons, japanese toothpicks, torrenting Photoshop, as well as what I used to find myself doing after a long evening of shooting mutants in Stargate.1 But, mostly? Yes. Mostly, I stood on a stage thousands of miles from the chair from which I barely move, and I told a lot of really smart people that they were nerds. I also told them they should get out more. I swear: it made sense at the time. Some Serious Talent My talk about the challenges and opportunities of being a giant nerd seemed well received. Honestly, I'm very happy with how it turned out. But--oh, brother--was I ever up against some heavy hitters. Serious Lou Gehrig shit. I'll leave it to other, more eloquent folks to tell you what a wonderful day this was. But I will very much suggest you learn this for yourself by listening to the audio of the fantastic talks. Because every one of them is a corker. Additionally, like I said, Tom Coates put on one of the loveliest slide decks it's ever been my pleasure to see (56MB PDF). Great speakers, great hosts, wonderful attendees (who aren't above buying a yank a pint [thanks, everybody]). And, Thanks, dConstruct I have to admit, I'm kind of over conferences as a thing, which makes it even more crazy when I go to one, and it blows me out of the water with the care and quality of the event, the speakers, and the attendees. dConstruct was absolutely one of those blown-out-of-the-water events. (photo: happy.apple) As I learned over and over again--yes, like me--these folks are nerds. But, brother are they ever talented nerds who care and care. Which I just love so much. I'll take a nerdy bunch of fontdorks and cellists over a splashy mega-conference full of VC pitches and skanks pushing free Red Bull anytime. Anytime. dConstruct was simply a top-notch operation from end-to-end, and I'm insanely grateful that I was invited to participate. Thanks, Clearleft. And, you, the reader? If you get the chance next time, go. Heck, I might even leave this chair and go there, myself. Maybe. I suppose when Dr. Who's over, I could just let these 20-sided dice decide for me. Lemme see...what's my Armor Class and Hit Points...? Listen for Yourself2 dConstruct Podcast MARTY NEUMEIER - The Designful Company The Designful Company on Huffduffer Download the audio | Huffduff it BRENDAN DAWES - Boil, Simmer, Reduce Boil, Simmer, Reduce on Huffduffer Download the audio | Huffduff it DAVID MCCANDLESS - Information Is Beautiful Information Is Beautiful on Huffduffer Download the audio | Huffduff it SAMANTHA WARREN - The Power and Beauty of Typography The Power and Beauty of Typography on Huffduffer Download the audio | Huffduff it JOHN GRUBER - The Auteur Theory Of Design The Auteur Theory Of Design on Huffduffer Download the audio | Huffduff it HANNAH DONOVAN - Jam Session: What Improvisation Can Teach Us About Design Jam Session: What Improvisation Can Teach Us About Design on Huffduffer Download the audio | Huffduff it JAMES BRIDLE - The Value Of Ruins The Value Of Ruins on Huffduffer Download the audio | Huffduff it TOM COATES - Everything The Network Touches Everything The Network Touches on Huffduffer Download the audio | Huffduff it Kerning, Orgasms And Those Goddamned Japanese Toothpicks ME - Kerning, Orgasms And Those Goddamned Japanese Toothpicks on Huffduffer Download the audio | Huffduff it Hint: Number Three. ↩ Code for these was stolen wholesale from the dConstruct site. Jeremy, et al - don't hesitate to tell me if that's a problem.Srsly. ↩ ”My Faith in Nerds: Stronger Than Any Gelatinous Cube” was written by Merlin Mann for 43Folders.com and was originally posted on September 10, 2010. Except as noted, it's ©2010 Merlin Mann and licensed for reuse under CC BY-NC-ND 3.0. "Why a footer?" Full Article dConstruct Geeks Knowledge Workers Nerds Speaking
latin The Platinum Jubilee of Her Majesty Queen Elizabeth II By www.chathamhouse.org Published On :: Wed, 01 Jun 2022 13:30:14 +0000 The Platinum Jubilee of Her Majesty Queen Elizabeth II News release NCapeling 1 June 2022 The staff, associate fellows and Council of the Royal Institute of International Affairs at Chatham House send congratulations and warmest wishes to Her Majesty Queen Elizabeth II on the occasion of her momentous Platinum Jubilee. As the Patron of the institute since her accession to the throne in 1952, HM The Queen has underpinned Chatham House’s independence for seven decades and thereby strengthened the impact of our work on the critical issues facing the world. HM The Queen lent her personal support to the establishment of the annual Chatham House Prize in 2005 and has presented the award in person on behalf of the institute’s members on three occasions. Among her other direct engagements with Chatham House, HM The Queen has helped us engage the next generation by supporting and then attending the launch of the Queen Elizabeth II Academy for Leadership in International Affairs in 2014, when she met the first intake of Academy fellows. We are enormously grateful for her continued involvement as Patron of the institute and wish her and the Royal Family a memorable Platinum Jubilee. Full Article
latin Microtubule affinity-regulating kinase 4 with an Alzheimer's disease-related mutation promotes tau accumulation and exacerbates neurodegeneration [Neurobiology] By www.jbc.org Published On :: 2020-12-11T00:06:20-08:00 Accumulation of the microtubule-associated protein tau is associated with Alzheimer's disease (AD). In AD brain, tau is abnormally phosphorylated at many sites, and phosphorylation at Ser-262 and Ser-356 plays critical roles in tau accumulation and toxicity. Microtubule affinity–regulating kinase 4 (MARK4) phosphorylates tau at those sites, and a double de novo mutation in the linker region of MARK4, ΔG316E317D, is associated with an elevated risk of AD. However, it remains unclear how this mutation affects phosphorylation, aggregation, and accumulation of tau and tau-induced neurodegeneration. Here, we report that MARK4ΔG316E317D increases the abundance of highly phosphorylated, insoluble tau species and exacerbates neurodegeneration via Ser-262/356–dependent and –independent mechanisms. Using transgenic Drosophila expressing human MARK4 (MARK4wt) or a mutant version of MARK4 (MARK4ΔG316E317D), we found that coexpression of MARK4wt and MARK4ΔG316E317D increased total tau levels and enhanced tau-induced neurodegeneration and that MARK4ΔG316E317D had more potent effects than MARK4wt. Interestingly, the in vitro kinase activities of MARK4wt and MARK4ΔG316E317D were similar. When tau phosphorylation at Ser-262 and Ser-356 was blocked by alanine substitutions, MARK4wt did not promote tau accumulation or exacerbate neurodegeneration, whereas coexpression of MARK4ΔG316E317D did. Both MARK4wt and MARK4ΔG316E317D increased the levels of oligomeric forms of tau; however, only MARK4ΔG316E317D further increased the detergent insolubility of tau in vivo. Together, these findings suggest that MARK4ΔG316E317D increases tau levels and exacerbates tau toxicity via a novel gain-of-function mechanism and that modification in this region of MARK4 may affect disease pathogenesis. Full Article
latin US election rhetoric on migration undermines Washington’s soft power in Latin America By www.chathamhouse.org Published On :: Wed, 23 Oct 2024 10:06:13 +0000 US election rhetoric on migration undermines Washington’s soft power in Latin America Expert comment jon.wallace 23 October 2024 As US public opinion hardens, the Democratic party takes a tougher stance, and Donald Trump proposes mass deportations, Latin American leaders note a lack of long-term policy. The US’s broken immigration system has become a central theme of the 2024 election campaign. But the discussion on immigration, undocumented immigrants, and asylum seekers – increasingly lurching into dehumanizing rhetoric – extends beyond US borders. As one former senior director of the National Security Council told me, ‘when the president travels or meets with heads of state from Latin America what comes up –regardless of the country – isn’t US–Cuba policy or even trade. It’s immigration’. How the US talks about and treats citizens of Latin American and the Caribbean matters to elected politicians in the region. The roots of the US immigration debate go deep and will not be easily resolved, even with a sweeping reform of the system. According to a January 2024 Pew survey, 78 per cent of Americans ‘say the large number of migrants seeking to enter the country at the Mexico border is either a crisis (45 per cent) or a major problem (32 per cent)’. Worries about the border are not limited to Republican voters: 73 per cent of Democrats feel that the issue is either a crisis or major problem. The numbers of undocumented immigrants encountered at the US–Mexico border has actually dropped in recent months. Despite the heated popular temperature, the numbers of undocumented immigrants encountered at the US–Mexico border has actually dropped in recent months. US Customs and Border Protection (USCBP) reported 301,981 encounters with irregular border crossings in December 2023; by August 2024 this had dropped to 107,473. Nevertheless, illegal border crossings have increased under Biden. During his administration USCBP reported 8 million encounters along the Mexico border compared to 2.5 million under Donald Trump. MexicoAny attempt to address the issue promises to affect US relations with Mexico, requiring the cooperation of newly elected president Claudia Sheinbaum. Her predecessor and founder of her Morena party, leftist Andres Manuel Lopez Obrador (AMLO), proved an unexpectedly cooperative partner for the previous Trump administration and Biden White House. In return for AMLO’s cooperation, the US soft-pedalled criticism over his failures to disrupt narcotics trafficking and criminal networks. But that came at a cost, particularly for Biden. In return for AMLO’s cooperation, the US soft-pedalled criticism over his failures to disrupt narcotics trafficking and criminal networks and for his steady weakening of checks on executive power. Mexico’s borders with other countries are also under pressure. Mexico remains the primary sending country to the US. But political repression and insecurity in countries including Cuba, Ecuador, Guatemala and Venezuela has pushed their citizens to travel across Mexico to the US. Economic collapse and humanitarian crises in Cuba and Venezuela have further fuelled the flight.RhetoricThe Kamala Harris and Trump campaigns have struck different positions on how to stem the flow of illegal immigration. But as US public opinion shifts, both parties are talking tougher. Related content Independent Thinking: What would a Harris presidency mean for the world? Harris is continuing Biden’s hardening stance, including the controversial move to bar those who cross the border illegally from applying for asylum. Biden’s early ‘roots’ strategy, to provide economic and security support in countries from where migrants are travelling, has fallen by the wayside. The Trump campaign is taking more extreme positions. The Republican presidential candidate mentions immigration in almost every campaign speech. He proposes to carry out the ‘largest deportation in US history’, using ICE personnel, the National Guard and local police forces to round up undocumented immigrants, including in their workplaces. The campaign has also pledged to end birth-right citizenship and Biden’s programme of parole for humanitarian reasons. Trump also plans to restore his first term policies including construction of the border wall. Trump’s proposals provide little opportunity for a broad, bipartisan consensus on immigration. Should he win in November he is likely, as he did in his first term, to attempt to push his policies via executive action, opening up challenges in federal court. The World Today Related content What a second Trump presidency would mean for the world A Harris victory would at least create space for the resurrection of the Biden administration’s 2024 immigration enforcement bill, originally supported by moderate Republican leadership in the Senate, but defeated following pressure from Trump. The bill would have toughened enforcement at the border – increasing funding for detention centres, asylum hearings and for local governments and border patrols. It would also permit ICE to shut down the border when crossings surpassed an average of 5,000 per day or 8,500 on a single day.Undermining US influenceBut such legislation, while promising to address domestic US perceptions of the crisis, threatens to reduce US soft power in Latin America. That would be counterproductive at a time when the US is attempting to consolidate global support in its competition with China and conflict with Russia. For Latin American leaders, US rhetoric on immigration rankles. The priorities of Latin American and Caribbean leaders and their voters are long term: economic growth, improved security, and climate change. These issues require investment and commitment from an engaged and reliable US partner. Sadly, Latin Americans can see such issues are not on the domestic agenda in US politics. To improve regional perceptions of US intentions after the election, new policy should seek to address the root causes of migration. That will require a multi-pronged, bipartisan approach that focuses attention and resources on US neighbours south of the border. Any future US administration will need to risk unpopularity with some voters at home and engage with sending countries and their neighbours. The US’s immigration system will need to broaden paths for legal immigration to meet US labour needs, while delivering increased support for border security, and accelerated (and humane) processes for detaining and repatriating illegal border crossers and asylum claims. But any sustainable answer also requires addressing the multifaceted reasons driving migrants north. Any future US administration will need to risk unpopularity with some voters at home and engage with sending countries and their neighbours. Full Article
latin Use of cyclodextrins for manipulating cellular cholesterol content By www.jlr.org Published On :: 1997-11-01 AE ChristianNov 1, 1997; 38:2264-2272Articles Full Article
latin Police make arrest relating to bags of cash that allegedly fell from Beryllium vehicle By jamaica-star.com Published On :: Mon, 11 Nov 2024 15:41:35 -0500 The police have arrested an individual in the probe surrounding two bags of cash that allegedly fell from a Beryllium security vehicle en route to the Norman Manley International Airport in Kingston last week. Full Article
latin Visualizing, quantifying, and manipulating mitochondrial DNA in vivo [Methods and Resources] By www.jbc.org Published On :: 2020-12-18T00:06:18-08:00 Mitochondrial DNA (mtDNA) encodes proteins and RNAs that support the functions of mitochondria and thereby numerous physiological processes. Mutations of mtDNA can cause mitochondrial diseases and are implicated in aging. The mtDNA within cells is organized into nucleoids within the mitochondrial matrix, but how mtDNA nucleoids are formed and regulated within cells remains incompletely resolved. Visualization of mtDNA within cells is a powerful means by which mechanistic insight can be gained. Manipulation of the amount and sequence of mtDNA within cells is important experimentally and for developing therapeutic interventions to treat mitochondrial disease. This review details recent developments and opportunities for improvements in the experimental tools and techniques that can be used to visualize, quantify, and manipulate the properties of mtDNA within cells. Full Article
latin NSun2 promotes cell migration through methylating autotaxin mRNA [Cell Biology] By www.jbc.org Published On :: 2020-12-25T00:06:30-08:00 NSun2 is an RNA methyltransferase introducing 5-methylcytosine into tRNAs, mRNAs, and noncoding RNAs, thereby influencing the levels or function of these RNAs. Autotaxin (ATX) is a secreted glycoprotein and is recognized as a key factor in converting lysophosphatidylcholine into lysophosphatidic acid (LPA). The ATX-LPA axis exerts multiple biological effects in cell survival, migration, proliferation, and differentiation. Here, we show that NSun2 is involved in the regulation of cell migration through methylating ATX mRNA. In the human glioma cell line U87, knockdown of NSun2 decreased ATX protein levels, whereas overexpression of NSun2 elevated ATX protein levels. However, neither overexpression nor knockdown of NSun2 altered ATX mRNA levels. Further studies revealed that NSun2 methylated the 3'-UTR of ATX mRNA at cytosine 2756 in vitro and in vivo. Methylation by NSun2 enhanced ATX mRNA translation. In addition, NSun2-mediated 5-methylcytosine methylation promoted the export of ATX mRNA from nucleus to cytoplasm in an ALYREF-dependent manner. Knockdown of NSun2 suppressed the migration of U87 cells, which was rescued by the addition of LPA. In summary, we identify NSun2-mediated methylation of ATX mRNA as a novel mechanism in the regulation of ATX. Full Article
latin Problem Notes for SAS®9 - 66294: The SAS Federation Server SPD driver fails to create a table that has a column name in UTF-8 encoding that also contains Latin5 characters By Published On :: Wed, 19 Aug 2020 15:57:34 EST Certain tables that are created in SAS Scalable Performance Data (SPD) Server might not be displayed correctly by SAS Federation Server Manager. Tables that have Latin5 characters in column names encounter this Full Article SPDS+SAS+Scalable+Peformance+Data+Server
latin Translating Divergent Environmental Stresses into a Common Proteome Response through Hik33 in a Model Cyanobacterium [Research] By www.mcponline.org Published On :: 2017-05-12T06:53:48-07:00 The histidine kinase Hik33 plays important roles in mediating cyanobacterial response to divergent types of abiotic stresses including cold, salt, high light (HL), and osmotic stresses. However, how these functions are regulated by Hik33 remains to be addressed. Using a hik33-deficient strain (hik33) of Synechocystis sp. PCC 6803 (Synechocystis) and quantitative proteomics, we found that Hik33 depletion induces differential protein expression highly similar to that induced by divergent types of stresses. This typically includes downregulation of proteins in photosynthesis and carbon assimilation that are necessary for cell propagation, and upregulation of heat shock proteins, chaperons, and proteases that are important for cell survival. This observation indicates that depletion of Hik33 alone mimics divergent types of abiotic stresses, and that Hik33 could be important for preventing abnormal stress response in the normal condition. Moreover, we found the majority of proteins of plasmid origin were significantly upregulated in hik33, though their biological significance remains to be addressed. Together, the systematically characterized Hik33-regulated cyanobacterial proteome, which is largely involved in stress responses, builds the molecular basis for Hik33 as a general regulator of stress responses. Full Article
latin Calculating glycoprotein similarities from mass spectrometric data [Review] By www.mcponline.org Published On :: 2020-09-03T11:35:14-07:00 Complex protein glycosylation occurs through biosynthetic steps in the secretory pathway that create macro- and microheterogeneity of structure and function. Required for all life forms, glycosylation diversifies and adapts protein interactions with binding partners that underpin interactions at cell surfaces and pericellular and extracellular environments. Because these biological effects arise from heterogeneity of structure and function, it is necessary to measure their changes as part of the quest to understand nature. Quite often, however, the assumption behind proteomics that post-translational modifications are discrete additions that can be modeled using the genome as a template does not apply to protein glycosylation. Rather, it is necessary to quantify the glycosylation distribution at each glycosite and to aggregate this information into a population of mature glycoproteins that exist in a given biological system. To date, mass spectrometric methods for assigning singly glycosylated peptides are well-established. But it is necessary to quantify glycosylation heterogeneity accurately in order to gauge the alterations that occur during biological processes. The task is to quantify the glycosylated peptide forms as accurately as possible and then apply appropriate bioinformatics algorithms to the calculation of micro- and macro-similarities. In this review, we summarize current approaches for protein quantification as they apply to this glycoprotein similarity problem. Full Article
latin Why a no-fly zone risks escalating the Ukraine conflict By www.chathamhouse.org Published On :: Sun, 13 Mar 2022 15:37:04 +0000 Why a no-fly zone risks escalating the Ukraine conflict Expert comment NCapeling 13 March 2022 The US rejection of Poland’s offer to send fighter jets as a boost to Ukraine’s air defence shows just how uneasy nations are about direct combat with Russia. The Pentagon’s decision to turn down the proposal by its fellow NATO member Poland to put Russian-made MiG-29 jets at its disposal demonstrates again how keen the US and allies are to avoid risking major confrontation with Russian forces. The US Department of Defense says the offer to locate jets at bases in Germany was ‘not tenable’ as this risks flying into contested airspace over Ukraine – a non-NATO member – raising ‘serious concerns for the entire NATO alliance’ and echoing the continuing rejection of calls to implement no-fly zones (NFZs) as a way of easing the devastation being faced by trapped Ukraine civilians. NFZs restrict any aircraft, including drones, from flying over a pre-defined region and can be used for both military and civilian purposes. But the implementation of NFZs is difficult to enforce and – most significantly – is unlikely to achieve the intended effect on the ground. In the long-term, under the terms of a ceasefire agreement, it may be possible to include a NFZ under a UN or joint OSCE-UN peace terms In conflict situations, they are usually implemented under the remit of United Nations (UN) peace support operations, requiring authorization under Article 42 of the UN Charter. This details that if all possible methods have proven ineffective in responding to a threat, countries ‘may take such action by air, or land forces as may be necessary to maintain or restore international peace and security’. Protection but with limitations NFZs provide both protection from attack and surveillance but do have limitations. They must be monitored and enforced which requires committing to fighter jet patrols with the explicit task of defending the area from the air by whatever means necessary. This could mean jets firing upon Russian planes and drones so, if NATO allies and partners were to enforce a NFZ, it would represent an escalation of measures which is a step that would most likely provoke an unpredictable Vladimir Putin into further escalation – in short, it is highly likely to be seen as an act of war. UK defence secretary Ben Wallace – among others – has repeatedly dispelled the idea, saying that enforcing NFZs would mean deploying ‘British fighter jets directly against Russian fighter jets’. In relation to moves such as the Polish jets, the Kremlin has warned that any countries offering airfields to Ukraine for attacks on Russia may be viewed as having entered the conflict. There have only been three past instances of military NFZs. In Bosnia, as part of Operation Deny Flight from 1993-1995, a NFZ was enforced as part of a strategy which also including the provision of close air support and approved air strikes. In Iraq, an NFZ endured for 12 years from 1991 and was succcesful in preventing Saddam Hussein from attacking Kurdish and Shia Muslim civilians. And in Libya in 2011, a NFZ was deployed to prevent the destruction of military infrastructure and the Libyan regime – although this quickly morphed into the provision of close air support. So it is unclear just how successful NFZs are at providing protection. In Iraq and Libya, NFZ cover protection was provided but neither Saddam Hussein or Colonel Gaddafi were able to effectively target victims through their ground forces whereas, in Bosnia, Slobodan Milosevic infamously used ground troops to slaughter 8,000 Bosnian men and boys at Srebrenica. Putin would still be able to continue to use both ground forces and artillery to assault Ukrainian cities with or without a NFZ – in fact, his sparse use of his Russian Aerospace Forces (VKS) has been one of the surprising features of the war so far. Under a NFZ, missile attacks could also continue, there is nothing in the record of no-fly zones to suggest the provision of safe areas for non-combatants would work. And NFZs have only been successful against vastly inferior forces such as in Iraq, Bosnia, and Libya. But Russia has an air force second only in size to the US and has a vast range of defences including the potent S-400 Triumf at its disposal. Not only would an NFZ be ineffective, it might also not be possible to enforce without risking significant losses to the peace operations force. It is due to a combination of these reasons that NFZs have not been used more in previous conflicts. The most recent consideration for a NFZ was in Syria but President Bashar al-Assad’s Syrian forces, protected by Russian air cover, could still have targeted their intended victims despite air policing so a NFZ was not used. If NATO allies and partners were to enforce a NFZ, it would represent an escalation of measures which is a step that would most likely provoke an unpredictable Vladimir Putin into further escalation In the long-term, under the terms of a ceasefire agreement, it may be possible to include a NFZ under a UN or joint OSCE-UN peace terms. However, the forces involved should exclude NATO allies and partners or any states with Russian alliances to avoid further conflict. This leaves few suitable countries with the capacity, willingness, and political stance to be called on. Two of the world’s most militarily capable states – China and India – abstained in the Uniting for Peace vote in the UN General Assembly (UNGA). Whether another willing state with the military capability – such as a Gulf state – could be considered acceptable to all sides remains to be tested. Notable successes with SAMs Many military commentators also note that currently Ukrainian forces are having notable success without jets, downing Russian aircraft using sophisticated surface-to-air missiles (SAMs) such as Stinger and Javelin, and NATO countries continue to supply those in their thousands. Full Article
latin Recipe for Scaling: ARQUIN Framework for Simulating a Distributed Quantum Computing System By www.hpcwire.com Published On :: Mon, 14 Oct 2024 21:24:34 +0000 One of the most difficult problems with quantum computing relates to increasing the size of the quantum computer. Researchers globally are seeking to solve this “challenge of scale.” To bring […] The post Recipe for Scaling: ARQUIN Framework for Simulating a Distributed Quantum Computing System appeared first on HPCwire. Full Article Short Takes
latin 1 in 3 American Indian, Black, and Latino Children Fall Into Digital Divide, Study Says By blogs.edweek.org Published On :: Wed, 22 Jul 2020 00:00:00 +0000 Nearly 17 million children lack high-speed internet at home that's considered crucial to their ability to participate in remote learning during the pandemic, according to a new study. Full Article Alaska
latin Latin America and the Caribbean redouble efforts to eradicate hunger By www.fao.org Published On :: Wed, 07 May 2014 00:00:00 GMT Representatives of all countries in Latin America and the Caribbean have gathered here this week to agree on the actions needed to definitively eradicate hunger in the region before 2025. [...] Full Article
latin FAO Director-General listed among the most influential Latin Americans By www.fao.org Published On :: Thu, 09 Feb 2017 00:00:00 GMT FAO Director-General José Graziano da Silva has been selected as one of the world's most influential Latin Americans for his work against hunger and malnutrition in the world. In its [...] Full Article
latin Latin lights in India By www.om.org Published On :: Fri, 10 Sep 2010 16:28:23 +0000 Thirteen young people from Latin America, including several OMers, spent their summer working in India. Eight of them are from Mexico, five from Costa Rica. They were on an exposure programme with India por Herencia, a partner organisation of OM Latin America. Full Article
latin Latin bridge to the least reached By www.om.org Published On :: Thu, 24 May 2018 21:50:56 +0000 Veracruz, Mexico :: Workers from Central Asia share their stories and challenge event participants to think about their part in global missions. Full Article
latin Police Shootings Lower Black and Latino Students' Grades, Graduation Rates, Study Shows By blogs.edweek.org Published On :: Wed, 10 Jun 2020 00:00:00 +0000 A new study shows that police shootings affect the learning and emotional well-being of students in nearby schools, particularly nonwhite students. Full Article Graduation+rates
latin Penn State Berks chancellor reaches out to Latino community in Spanish By www.psu.edu Published On :: Tue, 15 Oct 2024 17:17:59 -0400 Penn State Berks wrapped up its celebration of Hispanic Heritage Month on Oct. 11 with its 12th annual Latino Forum, an outreach effort for local high school students. Chancellor Radha Pyati provided a warm welcome to the students in Spanish, and she reached out to both students and the greater Latino community through a Facebook Live interview on La Mega Radio Station, a Spanish-language station who was on site for the event. Pyati was also interviewed live on La Mega’s Morning Show on Oct. 8. Full Article
