Imagine pulling a phone with a 12-inch screen from your pocket and stretching it to 18 inches. That's exactly what LG's new stretchable display promises.

The USDCAD moved higher in the Asian session and extended above the highs over the last few weeks between 1.3945 and 1.3958. The high price extended to 1.39664 but fell short of the 2022 high which came in at 1.3977.

The inability to move higher turn the buyers to sellers, and the price has rotated back down toward the close from yesterday's trade where buyers have stalled the fall.

On the downside, the next major target comes against the rising 100 and 200 hour moving averages between 1.3908 and 1.3911. It would take a move below that area to increase the bearish bias with the 100 bar moving average on a four hour chart the next downside target at 1.38868.

On the top side, getting back above 1.3945 and 1.3958 would have traders looking again toward the 2022 high at 1.3977. Get above that level opens the door for further upside potential.

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USDCAD Summary

The USDCAD rose in the Asian session, approaching 2022 highs.

Key Points:

1. Broke above recent highs (1.3945-1.3958).

2. Reached 1.39664, shy of 2022 high (1.3977).

3. Buyers turned sellers, and the price fell.

Outlook:

Bullish Scenario

Move above 1.3945, 1.3958, and 1.3977 confirms further upside.

Bearish Scenario

Break below 1.3908-1.3911 (100/200-hour MA) and 1.38868 (100-bar MA) increases bearish bias.

Levels to Watch:

• Resistance: 1.3945, 1.3958, 1.3977

• Support: 1.3908, 1.3911, 1.38868

The tenovins are a frequently studied class of compounds capable of inhibiting sirtuin activity, which is thought to result in increased acetylation and protection of the tumor suppressor p53 from degradation. However, as we and other laboratories have shown previously, certain tenovins are also capable of inhibiting autophagic flux, demonstrating the ability of these compounds to engage with more than one target. In this study, we present two additional mechanisms by which tenovins are able to activate p53 and kill tumor cells in culture. These mechanisms are the inhibition of a key enzyme of the de novo pyrimidine synthesis pathway, dihydroorotate dehydrogenase (DHODH), and the blockage of uridine transport into cells. These findings hold a 3-fold significance: first, we demonstrate that tenovins, and perhaps other compounds that activate p53, may activate p53 by more than one mechanism; second, that work previously conducted with certain tenovins as SirT1 inhibitors should additionally be viewed through the lens of DHODH inhibition as this is a major contributor to the mechanism of action of the most widely used tenovins; and finally, that small changes in the structure of a small molecule can lead to a dramatic change in the target profile of the molecule even when the phenotypic readout remains static.

The title hydrated mol­ecular salt (systematic name: tetra-n-butyl­ammonium 2,6-dioxo-1,2,3,6-tetra­hydro­pyrimidine-4-carboxyl­ate monohydrate), C16H36N+·C5H3N2O4−·H2O, crystallizes with N—H⋯O and O—H⋯O hydrogen-bonded double-stranded anti­parallel ribbons consisting of the hydro­philic orotate monoanions and water mol­ecules, separated by the bulky hydro­phobic cations. The hydro­phobic and hydro­philic regions of the structure are joined by weaker non-classical C—H⋯O hydrogen bonds. An accurate structure analysis conducted at T = 100 K is compared to a lower-resolution less accurate determination using data measured at T = 295 K. The results of both analyses are evaluated using a knowledge-based approach, and it is found that the less accurate room-temperature structure analysis provides geometric data that are similar to those derived from the accurate low-temperature analysis, with both sets of results consistent with previously analyzed structures. A minor disorder of one methyl group in the cation at low temperature was found to be slightly more complex at room temperature; while still involving a minor fraction of the structure, the disorder at room temperature was found to require a non-routine treatment, which is described in detail.

Adding compost, manure, and other forms of organic matter to farmland soil can boost earthworm numbers, crop yield, and the stability of soil, finds a recent analysis of long-term case studies. No-tillage and crop-rotation practices also have positive effects on soil, although no-tillage's benefits for earthworms are often absent on farms that use herbicides and other pesticides. The study also confirms that organic farming typically produces lower crop yields than conventional farming, but provides recommendations on how to reduce this ‘yield gap’, while highlighting positive aspects of organic agriculture.

Rotate your money in telecom, pharma & utilities sector: Krishna Kumar Karwa

Using CSS3 to rotate, slide and enlarge a set of images.

Apparatus and method for rotating an object using a music box mechanism having a spring motor. Apparatus includes a mechanical motor having a spring coupled between a body and a shaft of the music box where the shaft and the body are mounted for rotation relative to each other. The spring is windable by a user to store mechanical potential energy and when released, unwindable to release the stored energy and cause relative rotation between the body and the shaft. A base adapted for stationary placement against a surface such as a table or desktop or a wall or other stationary surface is fixedly coupled to or integrally formed with the shaft of the music box motor. An object such as a spherical planetary object or globe or any other object is connected to the body and includes an aperture or hole through which the base extends to the shaft. This aperture permits the object to rotate about the shaft without interference so that the body and the object rotate about the shaft as the spring unwinds. Connection of the winding mechanism shaft to the fixed base causes the body of the music box and attached object such as the globe to rotate.

In response to a visitor's query, this article deals with how you can turn an image on its side when a web page is viewed on a mobile phone.

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The sharing economy comes to architecture as the rich and the very rich share views and height.

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I wanted to know if it would be possible for companies to rotate the staff they have on furlough so we can all have a chance of earning our full salary - at least for a while?