target Targeting SARS-CoV-2 Through Innovation By www.medindia.net Published On :: Highlights: Interest in re-purposing neutralizing antibodies for therapeutic use against related viruses has been w Full Article
target Tax-News.com: Singapore Targets A More Progressive Tax Regime In 2022 Budget By www.tax-news.com Published On :: Mon, 21 Mar 2022 00:00:00 GMT Singapore has announced personal income tax hikes and higher wealth taxes on the territory's wealthiest individuals, as well as plans to ramp up the territory's carbon tax, in its newly released Budget. Full Article
target Treating Gum Disease With Gel that Targets Inflammation By www.medindia.net Published On :: A topical gel that blocks the receptor for a metabolic by-product called succinate treats gum disease by suppressing inflammation and changing the makeup Full Article
target Gene Target To Reduce Triglyceride, Cholesterol Levels by 50% By www.medindia.net Published On :: Using a variation of CRISPR gene editing may be a potential strategy for mimicking the protective effects of a genetic mutation linked to lower cholesterol levels and heart disease risks. Full Article
target Use of Mini-Proteins in Targeted Cancer Therapy By www.medindia.net Published On :: Mini-proteins are engineered protein capsule, bcapable of delivering targeted radiation dose directly to tumor cells expressing Nectin-4/b. Nectin-4 Full Article
target Fighting Glioblastoma: New Target Offers Hope for Brain Cancer Treatment By www.medindia.net Published On :: Newly discovered targets may hold the key to effectively treating glioblastoma, a deadly form of brain cancer. These targets were identified by screening Full Article
target Hope for Anxiety Sufferers: Scientists Identify Potential Target By www.medindia.net Published On :: Mental health conditions, including anxiety disorders, autism, and schizophrenia, are significant global health concerns. Researchers at Universite de Full Article
target Do RNA Provide a New Target for Alzheimer's Disease? By www.medindia.net Published On :: In a mouse model of Alzheimer's disease, decreasing the methylation of a key messenger RNA was found to enhance migration of macrophages into the brain Full Article
target Remodelling Signal Pathways in Prostate Cancer - A New Therapeutic Target! By www.medindia.net Published On :: medlinkCancer/medlink-causing mutations in prostate cancer hyperactivate PI3K signaling, leading to cancer cell growth. PLEKHS1, a largely unknown Full Article
target DMT1: A Promising New Target in the Fight Against Malaria By www.medindia.net Published On :: Malaria claims more than 600,000 lives annually, and as temperatures rise, the disease's potential spread is expanding. Although certain medications can Full Article
target Researchers Develop Rapid Screening System to Target Harmful Amyloid Proteins By www.medindia.net Published On :: An international research team led by the University of Toronto has created an effective system using the iC. elegans/i nematode to identify compounds that can halt the growth of amyloid proteins. Full Article
target Circadian Disruptions and Overeating: Can Targeting the Liver-Brain Pathway Help? By www.medindia.net Published On :: People who work night shifts or irregular hours and eat at inconsistent times are more susceptible to weight gain and diabetes, likely because their eating Full Article
target Targeting HMGB1: New Hope for Liver Disease Treatment By www.medindia.net Published On :: Acute and chronic liver diseases continue to be major clinical problems because of their high rates of morbidity and mortality. Acetaminophen (APAP) Full Article
target Teams target Champions League berth By blogs.siliconindia.com Published On :: Match factsDeccan v Bangalore, third-place playoff, MumbaiSaturday, April 24Start time 2000 (1430 GMT) Full Article target 'Inflation To Touch RBI's Mid-Term Target By 2018 End' By www.siliconindia.com Published On :: Global credit rating agency Fitch Ratings on Monday forecast that inflation in India would touch Reserve Bank of India's (RBI) medium term target range of two-six per cent by end 2018. Full Article target Extremists target ISKCON amid persecution of Hindus in Bangladesh By www.ibtimes.co.in Published On :: Sat, 09 Nov 2024 12:51:15 +0530 Author and social activist Taslima Nasreen has expressed deep concern regarding the persecution of minorities in Bangladesh at the hands of Islamist extremists. Full Article target Wiz CEO says company was targeted with deepfake attack that used his voice By techcrunch.com Published On :: Mon, 28 Oct 2024 18:10:46 +0000 Even cybersecurity companies aren’t safe from deepfake attacks. Speaking onstage at TechCrunch Disrupt in San Francisco, Wiz’s CEO and co-founder Assaf Rappaport, who recently turned down a $23 billion acquisition offer from Google, noted that his employees had been targeted by a deepfake attack just two weeks ago. “Dozens of my employees got a voice […] © 2024 TechCrunch. All rights reserved. For personal use only. Full Article Security AI wiz cloud security TechCrunch Disrupt 2024 Assaf Rappaport target ‘0ktapus’ hackers are back and targeting tech and gaming companies, says leaked report By techcrunch.com Published On :: Thu, 02 Feb 2023 20:31:52 +0000 The hackers who reportedly hit more than 130 organizations last year and stole the credentials of almost 10,000 employees are still targeting several tech and video game companies, according to a report obtained by TechCrunch. The report, prepared by cybersecurity firm CrowdStrike, calls the hackers “Scattered Spider.” In a previous publicly available report, the company […] © 2024 TechCrunch. All rights reserved. For personal use only. Full Article Security Comcast hackers Mailchimp Salesforce grubhub Intuit Riot Games Zynga cybersecurity CrowdStrike taskus target China Targets H&M With Xinjiang Propaganda Made for Home and Abroad By Published On :: Fri, 02 Apr 2021 12:03:49 GMT Beijing is beating back international criticism of its treatment of Uyghurs in Xinjiang with a propaganda push on Facebook, Twitter and the big screen. Here’s how China’s campaign against Western brands is aimed at audiences at home and abroad. Photo: Thomas Peter/Reuters Full Article target New AI Spoofing Scam Targets Millions of Gmail Users—Here's How to Be Safe By www.gizbot.com Published On :: Mon, 14 Oct 2024 17:45:21 +0530 A new scam is making its way through the Gmail ecosystem, using AI-powered tools to trick users into handing over access to their accounts. Security expert Sam Mitrovic, founder of CloudJoy, recently shared his experience with the scam, shedding light on Full Article target India Aims To Reach $100 Billion Trade Target With Russia Ahead Of 2030, Says Jaishankar By www.oneindia.com Published On :: Tue, 12 Nov 2024 20:42:01 +0530 India is on track to achieve a significant milestone in its economic partnership with Russia, with External Affairs Minister S. Jaishankar expressing confidence that the $100 billion trade target set for 2030 will be met well ahead of schedule. At the Full Article target Tech-Savvy But Targeted: Why Gen Z Falls Prey To Online Scams By www.oneindia.com Published On :: Tue, 10 Sep 2024 14:47:42 +0530 Siddharth (name changed) a second year BBA student from Koramangala, Bengaluru began chatting with a girl on WhatsApp who sent a link claiming to share photos. After opening the empty link, she went silent. Later, his mother unknowingly transferred Rs 50,000, Full Article target Shooting short-wavelength nonlinear optical materials with targeted balance performances in hydroxyborates through first-principles high-throughput screening By pubs.rsc.org Published On :: Inorg. Chem. Front., 2024, 11,7843-7852DOI: 10.1039/D4QI02234C, Research ArticleChenxu Li, Abudukadi Tudi, Huanhuan Cheng, Qingyu Liu, Zhihua Yang, Shilie PanHigh-throughput screening of 222 hydroxyborates identified three as promising short-wavelength ultraviolet nonlinear optical. with phase-matching second harmonic generation capacity extending to the solar blind region (200–280 nm).The content of this RSS Feed (c) The Royal Society of Chemistry Full Article target Multifunctional flexible magnetic drive gripper for target manipulation in complex constrained environments By pubs.rsc.org Published On :: Lab Chip, 2024, 24,2122-2134DOI: 10.1039/D3LC00945A, PaperMeiying Zhao, Ye Tao, Wenshang Guo, Zhenyou Ge, Hanqing Hu, Ying Yan, Chaoxia Zou, Guiyu Wang, Yukun RenA multifunctional flexible magnetic drive gripper is synthetically designed to achieve active steering and carry out operations on different targets in a constrained environment by changing the external magnetic field.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article target Construction of glutathione-responsive paclitaxel prodrug nanoparticles for image-guided targeted delivery and breast cancer therapy By pubs.rsc.org Published On :: RSC Adv., 2024, 14,12796-12806DOI: 10.1039/D4RA00610K, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Weiwei Ma, Qiufeng Zhao, Shilong Zhu, Xinyue Wang, Chuangchuang Zhang, Daming Ma, Na Li, Yanyan YinHA-coated redox sensitive visualized nano-prodrug HA/TPE-CS-SS-PTX were exploited in order to highly efficient treatment of cancer and real-time monitoring of drug localization.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article target Rational design of a lysosome-targeted fluorescent probe for monitoring the generation of hydroxyl radicals in ferroptosis pathways By pubs.rsc.org Published On :: RSC Adv., 2024, 14,12864-12872DOI: 10.1039/D4RA00562G, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Lili Zhong, Datian Fu, Jin Xu, Linyan Tan, Haimei Wu, Min WangA novel hydrocyanine-based turn-on fluorescence probe HCy-Lyso, with excellent lysosome-targeting ability and ˙OH-responsive efficiency, has been applied for monitoring the variation in lysosomal ˙OH levels during ferroptosis.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article target Cell-specific spatial profiling of targeted protein expression to characterize the impact of intracortical microelectrode implantation on neuronal health By pubs.rsc.org Published On :: J. Mater. Chem. B, 2024, Advance ArticleDOI: 10.1039/D4TB01628A, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Lindsey N. Druschel, Niveda M. Kasthuri, Sydney S. Song, Jaime J. Wang, Allison Hess-Dunning, E. Ricky Chan, Jeffrey R. CapadonaMultiplex immunochemistry for proteins examining neuronal structure or function in NeuN+ regions adjacent intracortical microelectrodes (MEA) more closely matched historic intracortical MEA recording performance than traditional IHC quantification.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article target A biomimetic solution, albumin–doxorubicin molecular complex, targeting tumor and tumor-draining lymph nodes By pubs.rsc.org Published On :: J. Mater. Chem. B, 2024, Advance ArticleDOI: 10.1039/D4TB01917B, PaperRui Guo, Lanlan Zhong, Sirui Ma, Bokai Gong, Chen Shen, Zijun Wang, Li Deng, Dong Zhao, Huile Gao, Tao GongChemotherapy-induced immunologic cell death is haunted by the non-specific distribution of chemotherapeutic drugs and insignificant immune activation effects, which render efforts to inhibit the distant metastasis of tumors frustrated.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article target A dual-functional photosensitizer for mitochondria-targeting photodynamic therapy and synchronous polarity monitoring By pubs.rsc.org Published On :: J. Mater. Chem. B, 2024, 12,11259-11264DOI: 10.1039/D4TB01872A, PaperLiu Yang, Shenglong Gan, Jie Zhang, Yin Jiang, Qingxin Chen, Hongyan SunA dual-functional photosensitizer was developed, exhibiting potent phototoxicity and sensitivity to polarity changes.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article target Chitosan-functionalized nanobubbles for precision oncology: advances in targeted cancer therapeutics By pubs.rsc.org Published On :: J. Mater. Chem. B, 2024, 12,11076-11088DOI: 10.1039/D4TB01930J, Review ArticleVivek Pandey, Tejasvi PandeyThe convergence of nanotechnology and cancer therapeutics has opened new frontiers in the development of advanced drug delivery systems.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article target Nanobiopolymers in cancer therapeutics: advancing targeted drug delivery through sustainable and controlled release mechanisms By pubs.rsc.org Published On :: J. Mater. Chem. B, 2024, Advance ArticleDOI: 10.1039/D4TB00599F, Review ArticleShikha Gulati, Nabeela Ansari, Yamini Moriya, Kumud Joshi, Disha Prasad, Gargi Sajwan, Shefali Shukla, Sanjay Kumar, Rajender S. VarmaNanobiopolymers in cancer therapeutics offer sustainable and targeted drug delivery with controlled release, enhancing treatment efficacy while ensuring sustainability and biodegradability for improved patient care.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article target Lactobionic acid modified cobalt coordination polymer-coated peroxymonosulfate nanoparticles generate sulfate/hydroxy dual-radicals for targeted cancer therapy By pubs.rsc.org Published On :: J. Mater. Chem. B, 2024, Advance ArticleDOI: 10.1039/D4TB01777C, PaperJiahui Li, Jiaxuan Li, Zelong Chen, Yichen Wan, Yi Wang, Zhichao Pei, Yuxin PeiLCP NPs were prepared by forming a coordination polymer on peroxymonosulfate through the coordination between imidazole-2-carboxaldehyde and Co2+, then modified with lactobionic acid to improve the efficacy of sulfate/hydroxy dual-radical therapy.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article target H2O2-activated mitochondria-targeting photosensitizer for fluorescence imaging-guided combination photodynamic and radiotherapy By pubs.rsc.org Published On :: J. Mater. Chem. B, 2024, Accepted ManuscriptDOI: 10.1039/D4TB01653J, PaperQiufen Tian, Zifan Zhu, Yun Feng, Shirui Zhao, Hui Lin, Wen Zhang, Zhiai XuRadiotherapy is a primary modality in cancer treatment but accompanied by severe side effects to healthy tissues and radiation resistance to some extent. To overcome these limitations, we developed a...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article target Functionalities of pH-responsive DNA nanostructures in tumor-targeted strategies By pubs.rsc.org Published On :: J. Mater. Chem. B, 2024, Advance ArticleDOI: 10.1039/D4TB01883D, Review ArticleLiyue Wen, Min WangDesign and application of various pH-responsive DNA nanostructures for tumor-targeted strategies toward extracellular and intracellular environments are comprehensively reviewed. Their potential and challenges are also critically discussed.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article target Utilizing solid-state nanopore sensing for high-efficiency and precise targeted localization in antiviral drug development By pubs.rsc.org Published On :: Analyst, 2024, 149,5313-5319DOI: 10.1039/D4AN00946K, PaperWei Xu, Lichun Zou, Haiyan Wang, Changhui Xu, Qinyang Fan, Jingjie ShaThe efficient identification and validation of drug targets are paramount in drug discovery and development.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article target Evaluating protocols for reproducible targeted metabolomics by NMR By pubs.rsc.org Published On :: Analyst, 2024, 149,5423-5432DOI: 10.1039/D4AN01015A, PaperDarcy Cochran, Panteleimon G. Takis, James L. Alexander, Benjamin H. Mullish, Nick Powell, Julian R. Marchesi, Robert PowersEvaluating how sample preparation methods and data analysis platforms impact measured metabolite concentrations underscores the need for a universal consensus in the followed approaches for metabolomics data analysis.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article target In silico validation of allosteric inhibitors targeting Zika virus NS2B–NS3 protease By pubs.rsc.org Published On :: Phys. Chem. Chem. Phys., 2024, 26,27684-27693DOI: 10.1039/D4CP02867H, PaperYeng-Tseng Wang, Yuan-Chin Hsieh, Tin-Yu WuThe Zika virus (ZIKV), a member of the Flaviviridae family, poses a major threat to human health because of the lack of effective antiviral drugs.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article target Targeted protein degradation directly engaging lysosomes or proteasomes By pubs.rsc.org Published On :: Chem. Soc. Rev., 2024, 53,3253-3272DOI: 10.1039/D3CS00344B, Tutorial Review Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Jiseong Kim, Insuk Byun, Do Young Kim, Hyunhi Joh, Hak Joong Kim, Min Jae LeeThis review delineates emerging technologies for targeted protein degradation that directly involve lysosomes or proteasomes. It explores their unique features, advantages, and limitations, offering perspectives on future therapeutic applications.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article target Mitochondria-targeted BODIPY dyes for small molecule recognition, bio-imaging and photodynamic therapy By pubs.rsc.org Published On :: Chem. Soc. Rev., 2024, 53,3976-4019DOI: 10.1039/D3CS00456B, Review ArticleSisi Wang, Lizhi Gai, Yuncong Chen, Xiaobo Ji, Hua Lu, Zijian GuoThis review focuses on the design strategy, spectroscopic characteristics, and functionalization of mitochondrion-targeted BODIPY dyes, providing an overview of these dyes for mitochondrion-targeted bioimaging and photodynamic therapy.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article target Mild boroxazolidone formation and dissociation: Application toward target identification of bioactive molecules By pubs.rsc.org Published On :: Chem. Commun., 2024, Accepted ManuscriptDOI: 10.1039/D4CC05370B, CommunicationToya Tabei, Kyoko Nagasawa-Goto, Yohei SaitoWe successfully found that boroxazolidone can dissociate under aqueous conditions, which were applicable to a solution containing proteins. The immobilization of a newly synthesized diarylborinic acid on beads enabled the...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article target ARCaDia: Single-round screening of a DNA-type targeted covalent binder possessing a latent warhead By pubs.rsc.org Published On :: Chem. Commun., 2024, Accepted ManuscriptDOI: 10.1039/D4CC04594G, Communication Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Masumi Taki, Masayasu Kuwahara, Chaohui Li, Naoko Tomoda, Naoyuki Miyashita, Tetsuo Kan, Jay YangA covalent binder for a target protein was obtained by a direct single-round screening of a latent-warhead-modified DNA library via affinity/reactivity-based co-selection of aptameric deoxyribonucleic acid (ARCaDia), followed by a...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article target Tailoring of novel morpholine-sulphonamide linked thiazole moiety as dual targeting DHFR/DNA gyrase inhibitors: Synthesis, antimicrobial, antibiofilm activities and DFT with molecular modelling studies By pubs.rsc.org Published On :: New J. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D3NJ05774G, PaperMoaz M. Abdou, Essam Eliwa, Mohamed Abdel Reheim, Ahmed Abu-Rayyan, Shimaa M. Abd El-Gilil, Mohammed Abu-Elghait , Mohamed H. Sharaf, Mohamed Kalaba, Ahmed Halawa, Walid ElgammalHerein, the chemical synthesis of new thiazoles-based benzenesulfonamide-linked morpholine 4a,b–7 via late-stage thiazolation of the corresponding thiosemicarbazone 3 was reported. The skeletal formulas of the new compounds were confirmed by...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article target Guanidine modification improves functions of natural RNA-targeting alkaloids By pubs.rsc.org Published On :: New J. Chem., 2024, Advance ArticleDOI: 10.1039/D3NJ05833F, Communication Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Tamaki Endoh, Sagar Satpathi, Yutong Chen, Saki Matsumoto, Tatsuya Ohyama, Peter Podbevšek, Janez Plavec, Kazumitsu Onizuka, Fumi Nagatsugi, Naoki SugimotoGuanidine modification on berberine improved RNA binding affinity and enhanced suppression of protein expression.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article target Govt 'in no hurry' on medium-term inflation target: Sources By www.thehindubusinessline.com Published On :: Wed, 21 Sep 2022 09:44:36 +0530 Government would be comfortable if central bank took two years or longer to get inflation down to 4 per cent: Sources Full Article Economy target India-Russia trade target of $100 bn realistic but urgent need for balance: Jaishankar By www.thehindubusinessline.com Published On :: Mon, 11 Nov 2024 13:27:01 +0530 Russia’s First Deputy PM Denis Manturov begins two-day India visit, attends India-Russia Business Forum Full Article Economy target Govt hopeful of meeting capital expenditure target for FY25 By www.thehindubusinessline.com Published On :: Mon, 11 Nov 2024 20:28:19 +0530 Big Push. Aims to meet ₹11.11 lakh crore capex target, may relax cash management norms in Jan-March quarter Full Article Economy target TiE Global Summit 2024 targets ₹100 crore in funding for start-up initiative By www.thehindubusinessline.com Published On :: Fri, 25 Oct 2024 20:44:33 +0530 The event will take place in Bangalore from December 9-11, 2024, and on December 12 in Mysore Full Article Info-tech target Progress targets $1 billion revenue with acquisition; expands Bangalore team By www.thehindubusinessline.com Published On :: Mon, 04 Nov 2024 18:56:03 +0530 The ShareFile business the company is acquiring generates approximately $240 million in revenue Full Article Info-tech target Use of ionic liquids in amidation reactions for proteolysis targeting chimera synthesis By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB00304G, PaperMichela Eleuteri, Jenny Desantis, Gabriele Cruciani, Raimondo Germani, Laura GoracciSelective degradation of disease-causing proteins using proteolysis targeting chimeras (PROTACs) has gained great attention, thanks to its several advantages over traditional therapeutic modalities.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article target Phishing attacks became more targeted this year: Report By www.thehindubusinessline.com Published On :: Mon, 24 Aug 2020 09:39:58 +0530 Hackers have been targeting delivery, postal, financial services and human resources Full Article Computers & Laptops «1..27 8 9..10..14..18..22..26..30..34..3839» Recent Trending Graybar Targets Ways to Make Business Strong and Sustainable Target Price Raised 69% on SMR Developer Target Price Raised 69% on SMR Developer Strong Investor Demand Pushes Oversubscribed Private Placement Beyond Target Warner Brothers job cuts determined by financial target Wanted Posters Targeting Jewish Faculty at NY Campus Australia builds on its strengths as a top 10 foreign investment target Bio blog: New therapy targeting the malaria parasite’s Achilles’ heel UBS maintain a US$2900 target for gold High Commissioner Thors, in her OSCE Permanent Council address, discusses country engagement and highlights the increase in hate speech targeting national minorities High Commissioner Thors, in her OSCE Permanent Council address, discusses country engagement and highlights the increase in hate speech targeting national minorities PRC Targeting of Commercial Telecommunications Infrastructure Beats Studio Buds have dropped to under $100 at Target Target is dropping daily and weekly doorbusters ahead of its weeklong Black Friday sale to understand the coordinated anti-Arab, anti-Muslim and anti-immigrant campaigns run with huge amounts of money targeting Europe Subscribe To Our Newsletter
target 'Inflation To Touch RBI's Mid-Term Target By 2018 End' By www.siliconindia.com Published On :: Global credit rating agency Fitch Ratings on Monday forecast that inflation in India would touch Reserve Bank of India's (RBI) medium term target range of two-six per cent by end 2018. Full Article
target Extremists target ISKCON amid persecution of Hindus in Bangladesh By www.ibtimes.co.in Published On :: Sat, 09 Nov 2024 12:51:15 +0530 Author and social activist Taslima Nasreen has expressed deep concern regarding the persecution of minorities in Bangladesh at the hands of Islamist extremists. Full Article
target Wiz CEO says company was targeted with deepfake attack that used his voice By techcrunch.com Published On :: Mon, 28 Oct 2024 18:10:46 +0000 Even cybersecurity companies aren’t safe from deepfake attacks. Speaking onstage at TechCrunch Disrupt in San Francisco, Wiz’s CEO and co-founder Assaf Rappaport, who recently turned down a $23 billion acquisition offer from Google, noted that his employees had been targeted by a deepfake attack just two weeks ago. “Dozens of my employees got a voice […] © 2024 TechCrunch. All rights reserved. For personal use only. Full Article Security AI wiz cloud security TechCrunch Disrupt 2024 Assaf Rappaport
target ‘0ktapus’ hackers are back and targeting tech and gaming companies, says leaked report By techcrunch.com Published On :: Thu, 02 Feb 2023 20:31:52 +0000 The hackers who reportedly hit more than 130 organizations last year and stole the credentials of almost 10,000 employees are still targeting several tech and video game companies, according to a report obtained by TechCrunch. The report, prepared by cybersecurity firm CrowdStrike, calls the hackers “Scattered Spider.” In a previous publicly available report, the company […] © 2024 TechCrunch. All rights reserved. For personal use only. Full Article Security Comcast hackers Mailchimp Salesforce grubhub Intuit Riot Games Zynga cybersecurity CrowdStrike taskus
target China Targets H&M With Xinjiang Propaganda Made for Home and Abroad By Published On :: Fri, 02 Apr 2021 12:03:49 GMT Beijing is beating back international criticism of its treatment of Uyghurs in Xinjiang with a propaganda push on Facebook, Twitter and the big screen. Here’s how China’s campaign against Western brands is aimed at audiences at home and abroad. Photo: Thomas Peter/Reuters Full Article
target New AI Spoofing Scam Targets Millions of Gmail Users—Here's How to Be Safe By www.gizbot.com Published On :: Mon, 14 Oct 2024 17:45:21 +0530 A new scam is making its way through the Gmail ecosystem, using AI-powered tools to trick users into handing over access to their accounts. Security expert Sam Mitrovic, founder of CloudJoy, recently shared his experience with the scam, shedding light on Full Article
target India Aims To Reach $100 Billion Trade Target With Russia Ahead Of 2030, Says Jaishankar By www.oneindia.com Published On :: Tue, 12 Nov 2024 20:42:01 +0530 India is on track to achieve a significant milestone in its economic partnership with Russia, with External Affairs Minister S. Jaishankar expressing confidence that the $100 billion trade target set for 2030 will be met well ahead of schedule. At the Full Article
target Tech-Savvy But Targeted: Why Gen Z Falls Prey To Online Scams By www.oneindia.com Published On :: Tue, 10 Sep 2024 14:47:42 +0530 Siddharth (name changed) a second year BBA student from Koramangala, Bengaluru began chatting with a girl on WhatsApp who sent a link claiming to share photos. After opening the empty link, she went silent. Later, his mother unknowingly transferred Rs 50,000, Full Article
target Shooting short-wavelength nonlinear optical materials with targeted balance performances in hydroxyborates through first-principles high-throughput screening By pubs.rsc.org Published On :: Inorg. Chem. Front., 2024, 11,7843-7852DOI: 10.1039/D4QI02234C, Research ArticleChenxu Li, Abudukadi Tudi, Huanhuan Cheng, Qingyu Liu, Zhihua Yang, Shilie PanHigh-throughput screening of 222 hydroxyborates identified three as promising short-wavelength ultraviolet nonlinear optical. with phase-matching second harmonic generation capacity extending to the solar blind region (200–280 nm).The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
target Multifunctional flexible magnetic drive gripper for target manipulation in complex constrained environments By pubs.rsc.org Published On :: Lab Chip, 2024, 24,2122-2134DOI: 10.1039/D3LC00945A, PaperMeiying Zhao, Ye Tao, Wenshang Guo, Zhenyou Ge, Hanqing Hu, Ying Yan, Chaoxia Zou, Guiyu Wang, Yukun RenA multifunctional flexible magnetic drive gripper is synthetically designed to achieve active steering and carry out operations on different targets in a constrained environment by changing the external magnetic field.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
target Construction of glutathione-responsive paclitaxel prodrug nanoparticles for image-guided targeted delivery and breast cancer therapy By pubs.rsc.org Published On :: RSC Adv., 2024, 14,12796-12806DOI: 10.1039/D4RA00610K, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Weiwei Ma, Qiufeng Zhao, Shilong Zhu, Xinyue Wang, Chuangchuang Zhang, Daming Ma, Na Li, Yanyan YinHA-coated redox sensitive visualized nano-prodrug HA/TPE-CS-SS-PTX were exploited in order to highly efficient treatment of cancer and real-time monitoring of drug localization.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
target Rational design of a lysosome-targeted fluorescent probe for monitoring the generation of hydroxyl radicals in ferroptosis pathways By pubs.rsc.org Published On :: RSC Adv., 2024, 14,12864-12872DOI: 10.1039/D4RA00562G, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Lili Zhong, Datian Fu, Jin Xu, Linyan Tan, Haimei Wu, Min WangA novel hydrocyanine-based turn-on fluorescence probe HCy-Lyso, with excellent lysosome-targeting ability and ˙OH-responsive efficiency, has been applied for monitoring the variation in lysosomal ˙OH levels during ferroptosis.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
target Cell-specific spatial profiling of targeted protein expression to characterize the impact of intracortical microelectrode implantation on neuronal health By pubs.rsc.org Published On :: J. Mater. Chem. B, 2024, Advance ArticleDOI: 10.1039/D4TB01628A, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Lindsey N. Druschel, Niveda M. Kasthuri, Sydney S. Song, Jaime J. Wang, Allison Hess-Dunning, E. Ricky Chan, Jeffrey R. CapadonaMultiplex immunochemistry for proteins examining neuronal structure or function in NeuN+ regions adjacent intracortical microelectrodes (MEA) more closely matched historic intracortical MEA recording performance than traditional IHC quantification.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
target A biomimetic solution, albumin–doxorubicin molecular complex, targeting tumor and tumor-draining lymph nodes By pubs.rsc.org Published On :: J. Mater. Chem. B, 2024, Advance ArticleDOI: 10.1039/D4TB01917B, PaperRui Guo, Lanlan Zhong, Sirui Ma, Bokai Gong, Chen Shen, Zijun Wang, Li Deng, Dong Zhao, Huile Gao, Tao GongChemotherapy-induced immunologic cell death is haunted by the non-specific distribution of chemotherapeutic drugs and insignificant immune activation effects, which render efforts to inhibit the distant metastasis of tumors frustrated.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
target A dual-functional photosensitizer for mitochondria-targeting photodynamic therapy and synchronous polarity monitoring By pubs.rsc.org Published On :: J. Mater. Chem. B, 2024, 12,11259-11264DOI: 10.1039/D4TB01872A, PaperLiu Yang, Shenglong Gan, Jie Zhang, Yin Jiang, Qingxin Chen, Hongyan SunA dual-functional photosensitizer was developed, exhibiting potent phototoxicity and sensitivity to polarity changes.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
target Chitosan-functionalized nanobubbles for precision oncology: advances in targeted cancer therapeutics By pubs.rsc.org Published On :: J. Mater. Chem. B, 2024, 12,11076-11088DOI: 10.1039/D4TB01930J, Review ArticleVivek Pandey, Tejasvi PandeyThe convergence of nanotechnology and cancer therapeutics has opened new frontiers in the development of advanced drug delivery systems.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
target Nanobiopolymers in cancer therapeutics: advancing targeted drug delivery through sustainable and controlled release mechanisms By pubs.rsc.org Published On :: J. Mater. Chem. B, 2024, Advance ArticleDOI: 10.1039/D4TB00599F, Review ArticleShikha Gulati, Nabeela Ansari, Yamini Moriya, Kumud Joshi, Disha Prasad, Gargi Sajwan, Shefali Shukla, Sanjay Kumar, Rajender S. VarmaNanobiopolymers in cancer therapeutics offer sustainable and targeted drug delivery with controlled release, enhancing treatment efficacy while ensuring sustainability and biodegradability for improved patient care.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
target Lactobionic acid modified cobalt coordination polymer-coated peroxymonosulfate nanoparticles generate sulfate/hydroxy dual-radicals for targeted cancer therapy By pubs.rsc.org Published On :: J. Mater. Chem. B, 2024, Advance ArticleDOI: 10.1039/D4TB01777C, PaperJiahui Li, Jiaxuan Li, Zelong Chen, Yichen Wan, Yi Wang, Zhichao Pei, Yuxin PeiLCP NPs were prepared by forming a coordination polymer on peroxymonosulfate through the coordination between imidazole-2-carboxaldehyde and Co2+, then modified with lactobionic acid to improve the efficacy of sulfate/hydroxy dual-radical therapy.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
target H2O2-activated mitochondria-targeting photosensitizer for fluorescence imaging-guided combination photodynamic and radiotherapy By pubs.rsc.org Published On :: J. Mater. Chem. B, 2024, Accepted ManuscriptDOI: 10.1039/D4TB01653J, PaperQiufen Tian, Zifan Zhu, Yun Feng, Shirui Zhao, Hui Lin, Wen Zhang, Zhiai XuRadiotherapy is a primary modality in cancer treatment but accompanied by severe side effects to healthy tissues and radiation resistance to some extent. To overcome these limitations, we developed a...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
target Functionalities of pH-responsive DNA nanostructures in tumor-targeted strategies By pubs.rsc.org Published On :: J. Mater. Chem. B, 2024, Advance ArticleDOI: 10.1039/D4TB01883D, Review ArticleLiyue Wen, Min WangDesign and application of various pH-responsive DNA nanostructures for tumor-targeted strategies toward extracellular and intracellular environments are comprehensively reviewed. Their potential and challenges are also critically discussed.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
target Utilizing solid-state nanopore sensing for high-efficiency and precise targeted localization in antiviral drug development By pubs.rsc.org Published On :: Analyst, 2024, 149,5313-5319DOI: 10.1039/D4AN00946K, PaperWei Xu, Lichun Zou, Haiyan Wang, Changhui Xu, Qinyang Fan, Jingjie ShaThe efficient identification and validation of drug targets are paramount in drug discovery and development.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
target Evaluating protocols for reproducible targeted metabolomics by NMR By pubs.rsc.org Published On :: Analyst, 2024, 149,5423-5432DOI: 10.1039/D4AN01015A, PaperDarcy Cochran, Panteleimon G. Takis, James L. Alexander, Benjamin H. Mullish, Nick Powell, Julian R. Marchesi, Robert PowersEvaluating how sample preparation methods and data analysis platforms impact measured metabolite concentrations underscores the need for a universal consensus in the followed approaches for metabolomics data analysis.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
target In silico validation of allosteric inhibitors targeting Zika virus NS2B–NS3 protease By pubs.rsc.org Published On :: Phys. Chem. Chem. Phys., 2024, 26,27684-27693DOI: 10.1039/D4CP02867H, PaperYeng-Tseng Wang, Yuan-Chin Hsieh, Tin-Yu WuThe Zika virus (ZIKV), a member of the Flaviviridae family, poses a major threat to human health because of the lack of effective antiviral drugs.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
target Targeted protein degradation directly engaging lysosomes or proteasomes By pubs.rsc.org Published On :: Chem. Soc. Rev., 2024, 53,3253-3272DOI: 10.1039/D3CS00344B, Tutorial Review Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Jiseong Kim, Insuk Byun, Do Young Kim, Hyunhi Joh, Hak Joong Kim, Min Jae LeeThis review delineates emerging technologies for targeted protein degradation that directly involve lysosomes or proteasomes. It explores their unique features, advantages, and limitations, offering perspectives on future therapeutic applications.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
target Mitochondria-targeted BODIPY dyes for small molecule recognition, bio-imaging and photodynamic therapy By pubs.rsc.org Published On :: Chem. Soc. Rev., 2024, 53,3976-4019DOI: 10.1039/D3CS00456B, Review ArticleSisi Wang, Lizhi Gai, Yuncong Chen, Xiaobo Ji, Hua Lu, Zijian GuoThis review focuses on the design strategy, spectroscopic characteristics, and functionalization of mitochondrion-targeted BODIPY dyes, providing an overview of these dyes for mitochondrion-targeted bioimaging and photodynamic therapy.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
target Mild boroxazolidone formation and dissociation: Application toward target identification of bioactive molecules By pubs.rsc.org Published On :: Chem. Commun., 2024, Accepted ManuscriptDOI: 10.1039/D4CC05370B, CommunicationToya Tabei, Kyoko Nagasawa-Goto, Yohei SaitoWe successfully found that boroxazolidone can dissociate under aqueous conditions, which were applicable to a solution containing proteins. The immobilization of a newly synthesized diarylborinic acid on beads enabled the...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
target ARCaDia: Single-round screening of a DNA-type targeted covalent binder possessing a latent warhead By pubs.rsc.org Published On :: Chem. Commun., 2024, Accepted ManuscriptDOI: 10.1039/D4CC04594G, Communication Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Masumi Taki, Masayasu Kuwahara, Chaohui Li, Naoko Tomoda, Naoyuki Miyashita, Tetsuo Kan, Jay YangA covalent binder for a target protein was obtained by a direct single-round screening of a latent-warhead-modified DNA library via affinity/reactivity-based co-selection of aptameric deoxyribonucleic acid (ARCaDia), followed by a...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
target Tailoring of novel morpholine-sulphonamide linked thiazole moiety as dual targeting DHFR/DNA gyrase inhibitors: Synthesis, antimicrobial, antibiofilm activities and DFT with molecular modelling studies By pubs.rsc.org Published On :: New J. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D3NJ05774G, PaperMoaz M. Abdou, Essam Eliwa, Mohamed Abdel Reheim, Ahmed Abu-Rayyan, Shimaa M. Abd El-Gilil, Mohammed Abu-Elghait , Mohamed H. Sharaf, Mohamed Kalaba, Ahmed Halawa, Walid ElgammalHerein, the chemical synthesis of new thiazoles-based benzenesulfonamide-linked morpholine 4a,b–7 via late-stage thiazolation of the corresponding thiosemicarbazone 3 was reported. The skeletal formulas of the new compounds were confirmed by...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
target Guanidine modification improves functions of natural RNA-targeting alkaloids By pubs.rsc.org Published On :: New J. Chem., 2024, Advance ArticleDOI: 10.1039/D3NJ05833F, Communication Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Tamaki Endoh, Sagar Satpathi, Yutong Chen, Saki Matsumoto, Tatsuya Ohyama, Peter Podbevšek, Janez Plavec, Kazumitsu Onizuka, Fumi Nagatsugi, Naoki SugimotoGuanidine modification on berberine improved RNA binding affinity and enhanced suppression of protein expression.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
target Govt 'in no hurry' on medium-term inflation target: Sources By www.thehindubusinessline.com Published On :: Wed, 21 Sep 2022 09:44:36 +0530 Government would be comfortable if central bank took two years or longer to get inflation down to 4 per cent: Sources Full Article Economy
target India-Russia trade target of $100 bn realistic but urgent need for balance: Jaishankar By www.thehindubusinessline.com Published On :: Mon, 11 Nov 2024 13:27:01 +0530 Russia’s First Deputy PM Denis Manturov begins two-day India visit, attends India-Russia Business Forum Full Article Economy
target Govt hopeful of meeting capital expenditure target for FY25 By www.thehindubusinessline.com Published On :: Mon, 11 Nov 2024 20:28:19 +0530 Big Push. Aims to meet ₹11.11 lakh crore capex target, may relax cash management norms in Jan-March quarter Full Article Economy
target TiE Global Summit 2024 targets ₹100 crore in funding for start-up initiative By www.thehindubusinessline.com Published On :: Fri, 25 Oct 2024 20:44:33 +0530 The event will take place in Bangalore from December 9-11, 2024, and on December 12 in Mysore Full Article Info-tech
target Progress targets $1 billion revenue with acquisition; expands Bangalore team By www.thehindubusinessline.com Published On :: Mon, 04 Nov 2024 18:56:03 +0530 The ShareFile business the company is acquiring generates approximately $240 million in revenue Full Article Info-tech
target Use of ionic liquids in amidation reactions for proteolysis targeting chimera synthesis By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB00304G, PaperMichela Eleuteri, Jenny Desantis, Gabriele Cruciani, Raimondo Germani, Laura GoracciSelective degradation of disease-causing proteins using proteolysis targeting chimeras (PROTACs) has gained great attention, thanks to its several advantages over traditional therapeutic modalities.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
target Phishing attacks became more targeted this year: Report By www.thehindubusinessline.com Published On :: Mon, 24 Aug 2020 09:39:58 +0530 Hackers have been targeting delivery, postal, financial services and human resources Full Article Computers & Laptops
