target
Targeting SARS-CoV-2 Through Innovation
Highlights: Interest in re-purposing neutralizing antibodies for therapeutic use against related viruses has been w
target
Tax-News.com: Singapore Targets A More Progressive Tax Regime In 2022 Budget
Singapore has announced personal income tax hikes and higher wealth taxes on the territory's wealthiest individuals, as well as plans to ramp up the territory's carbon tax, in its newly released Budget.
target
Treating Gum Disease With Gel that Targets Inflammation
A topical gel that blocks the receptor for a metabolic by-product called succinate treats gum disease by suppressing inflammation and changing the makeup
target
Gene Target To Reduce Triglyceride, Cholesterol Levels by 50%
Using a variation of CRISPR gene editing may be a potential strategy for mimicking the protective effects of a genetic mutation linked to lower cholesterol levels and heart disease risks.
target
Use of Mini-Proteins in Targeted Cancer Therapy
Mini-proteins are engineered protein capsule, bcapable of delivering targeted radiation dose directly to tumor cells expressing Nectin-4/b. Nectin-4
target
Fighting Glioblastoma: New Target Offers Hope for Brain Cancer Treatment
Newly discovered targets may hold the key to effectively treating glioblastoma, a deadly form of brain cancer. These targets were identified by screening
target
Hope for Anxiety Sufferers: Scientists Identify Potential Target
Mental health conditions, including anxiety disorders, autism, and schizophrenia, are significant global health concerns. Researchers at Universite de
target
Do RNA Provide a New Target for Alzheimer's Disease?
In a mouse model of Alzheimer's disease, decreasing the methylation of a key messenger RNA was found to enhance migration of macrophages into the brain
target
Remodelling Signal Pathways in Prostate Cancer - A New Therapeutic Target!
medlinkCancer/medlink-causing mutations in prostate cancer hyperactivate PI3K signaling, leading to cancer cell growth. PLEKHS1, a largely unknown
target
DMT1: A Promising New Target in the Fight Against Malaria
Malaria claims more than 600,000 lives annually, and as temperatures rise, the disease's potential spread is expanding. Although certain medications can
target
Researchers Develop Rapid Screening System to Target Harmful Amyloid Proteins
An international research team led by the University of Toronto has created an effective system using the iC. elegans/i nematode to identify compounds that can halt the growth of amyloid proteins.
target
Circadian Disruptions and Overeating: Can Targeting the Liver-Brain Pathway Help?
People who work night shifts or irregular hours and eat at inconsistent times are more susceptible to weight gain and diabetes, likely because their eating
target
Targeting HMGB1: New Hope for Liver Disease Treatment
Acute and chronic liver diseases continue to be major clinical problems because of their high rates of morbidity and mortality. Acetaminophen (APAP)
target
Teams target Champions League berth
Match facts
Deccan v Bangalore, third-place playoff, MumbaiSaturday, April 24
Start time 2000 (1430 GMT)
Full Article
target
'Inflation To Touch RBI's Mid-Term Target By 2018 End'
Global credit rating agency Fitch Ratings on Monday forecast that inflation in India would touch Reserve Bank of India's (RBI) medium term target range of two-six per cent by end 2018.
target
Extremists target ISKCON amid persecution of Hindus in Bangladesh
Author and social activist Taslima Nasreen has expressed deep concern regarding the persecution of minorities in Bangladesh at the hands of Islamist extremists.
target
Wiz CEO says company was targeted with deepfake attack that used his voice
Even cybersecurity companies aren’t safe from deepfake attacks. Speaking onstage at TechCrunch Disrupt in San Francisco, Wiz’s CEO and co-founder Assaf Rappaport, who recently turned down a $23 billion acquisition offer from Google, noted that his employees had been targeted by a deepfake attack just two weeks ago. “Dozens of my employees got a voice […]
© 2024 TechCrunch. All rights reserved. For personal use only.
target
‘0ktapus’ hackers are back and targeting tech and gaming companies, says leaked report
The hackers who reportedly hit more than 130 organizations last year and stole the credentials of almost 10,000 employees are still targeting several tech and video game companies, according to a report obtained by TechCrunch. The report, prepared by cybersecurity firm CrowdStrike, calls the hackers “Scattered Spider.” In a previous publicly available report, the company […]
© 2024 TechCrunch. All rights reserved. For personal use only.
target
China Targets H&M With Xinjiang Propaganda Made for Home and Abroad
Beijing is beating back international criticism of its treatment of Uyghurs in Xinjiang with a propaganda push on Facebook, Twitter and the big screen. Here’s how China’s campaign against Western brands is aimed at audiences at home and abroad. Photo: Thomas Peter/Reuters
target
New AI Spoofing Scam Targets Millions of Gmail Users—Here's How to Be Safe
A new scam is making its way through the Gmail ecosystem, using AI-powered tools to trick users into handing over access to their accounts. Security expert Sam Mitrovic, founder of CloudJoy, recently shared his experience with the scam, shedding light on
target
India Aims To Reach $100 Billion Trade Target With Russia Ahead Of 2030, Says Jaishankar
India is on track to achieve a significant milestone in its economic partnership with Russia, with External Affairs Minister S. Jaishankar expressing confidence that the $100 billion trade target set for 2030 will be met well ahead of schedule. At the
target
Tech-Savvy But Targeted: Why Gen Z Falls Prey To Online Scams
Siddharth (name changed) a second year BBA student from Koramangala, Bengaluru began chatting with a girl on WhatsApp who sent a link claiming to share photos. After opening the empty link, she went silent. Later, his mother unknowingly transferred Rs 50,000,
target
Shooting short-wavelength nonlinear optical materials with targeted balance performances in hydroxyborates through first-principles high-throughput screening
Inorg. Chem. Front., 2024, 11,7843-7852
DOI: 10.1039/D4QI02234C, Research Article
DOI: 10.1039/D4QI02234C, Research Article
Chenxu Li, Abudukadi Tudi, Huanhuan Cheng, Qingyu Liu, Zhihua Yang, Shilie Pan
High-throughput screening of 222 hydroxyborates identified three as promising short-wavelength ultraviolet nonlinear optical. with phase-matching second harmonic generation capacity extending to the solar blind region (200–280 nm).
The content of this RSS Feed (c) The Royal Society of Chemistry
High-throughput screening of 222 hydroxyborates identified three as promising short-wavelength ultraviolet nonlinear optical. with phase-matching second harmonic generation capacity extending to the solar blind region (200–280 nm).
The content of this RSS Feed (c) The Royal Society of Chemistry
target
Multifunctional flexible magnetic drive gripper for target manipulation in complex constrained environments
Lab Chip, 2024, 24,2122-2134
DOI: 10.1039/D3LC00945A, Paper
DOI: 10.1039/D3LC00945A, Paper
Meiying Zhao, Ye Tao, Wenshang Guo, Zhenyou Ge, Hanqing Hu, Ying Yan, Chaoxia Zou, Guiyu Wang, Yukun Ren
A multifunctional flexible magnetic drive gripper is synthetically designed to achieve active steering and carry out operations on different targets in a constrained environment by changing the external magnetic field.
The content of this RSS Feed (c) The Royal Society of Chemistry
A multifunctional flexible magnetic drive gripper is synthetically designed to achieve active steering and carry out operations on different targets in a constrained environment by changing the external magnetic field.
The content of this RSS Feed (c) The Royal Society of Chemistry
target
Construction of glutathione-responsive paclitaxel prodrug nanoparticles for image-guided targeted delivery and breast cancer therapy
RSC Adv., 2024, 14,12796-12806
DOI: 10.1039/D4RA00610K, Paper
DOI: 10.1039/D4RA00610K, Paper
Open Access
This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.
Weiwei Ma, Qiufeng Zhao, Shilong Zhu, Xinyue Wang, Chuangchuang Zhang, Daming Ma, Na Li, Yanyan Yin
HA-coated redox sensitive visualized nano-prodrug HA/TPE-CS-SS-PTX were exploited in order to highly efficient treatment of cancer and real-time monitoring of drug localization.
The content of this RSS Feed (c) The Royal Society of Chemistry
HA-coated redox sensitive visualized nano-prodrug HA/TPE-CS-SS-PTX were exploited in order to highly efficient treatment of cancer and real-time monitoring of drug localization.
The content of this RSS Feed (c) The Royal Society of Chemistry
target
Rational design of a lysosome-targeted fluorescent probe for monitoring the generation of hydroxyl radicals in ferroptosis pathways
RSC Adv., 2024, 14,12864-12872
DOI: 10.1039/D4RA00562G, Paper
DOI: 10.1039/D4RA00562G, Paper
Open Access
This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.
Lili Zhong, Datian Fu, Jin Xu, Linyan Tan, Haimei Wu, Min Wang
A novel hydrocyanine-based turn-on fluorescence probe HCy-Lyso, with excellent lysosome-targeting ability and ˙OH-responsive efficiency, has been applied for monitoring the variation in lysosomal ˙OH levels during ferroptosis.
The content of this RSS Feed (c) The Royal Society of Chemistry
A novel hydrocyanine-based turn-on fluorescence probe HCy-Lyso, with excellent lysosome-targeting ability and ˙OH-responsive efficiency, has been applied for monitoring the variation in lysosomal ˙OH levels during ferroptosis.
The content of this RSS Feed (c) The Royal Society of Chemistry
target
Cell-specific spatial profiling of targeted protein expression to characterize the impact of intracortical microelectrode implantation on neuronal health
J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01628A, Paper
DOI: 10.1039/D4TB01628A, Paper
Open Access
This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.
Lindsey N. Druschel, Niveda M. Kasthuri, Sydney S. Song, Jaime J. Wang, Allison Hess-Dunning, E. Ricky Chan, Jeffrey R. Capadona
Multiplex immunochemistry for proteins examining neuronal structure or function in NeuN+ regions adjacent intracortical microelectrodes (MEA) more closely matched historic intracortical MEA recording performance than traditional IHC quantification.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry
Multiplex immunochemistry for proteins examining neuronal structure or function in NeuN+ regions adjacent intracortical microelectrodes (MEA) more closely matched historic intracortical MEA recording performance than traditional IHC quantification.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry
target
A biomimetic solution, albumin–doxorubicin molecular complex, targeting tumor and tumor-draining lymph nodes
J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01917B, Paper
DOI: 10.1039/D4TB01917B, Paper
Rui Guo, Lanlan Zhong, Sirui Ma, Bokai Gong, Chen Shen, Zijun Wang, Li Deng, Dong Zhao, Huile Gao, Tao Gong
Chemotherapy-induced immunologic cell death is haunted by the non-specific distribution of chemotherapeutic drugs and insignificant immune activation effects, which render efforts to inhibit the distant metastasis of tumors frustrated.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry
Chemotherapy-induced immunologic cell death is haunted by the non-specific distribution of chemotherapeutic drugs and insignificant immune activation effects, which render efforts to inhibit the distant metastasis of tumors frustrated.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry
target
A dual-functional photosensitizer for mitochondria-targeting photodynamic therapy and synchronous polarity monitoring
J. Mater. Chem. B, 2024, 12,11259-11264
DOI: 10.1039/D4TB01872A, Paper
DOI: 10.1039/D4TB01872A, Paper
Liu Yang, Shenglong Gan, Jie Zhang, Yin Jiang, Qingxin Chen, Hongyan Sun
A dual-functional photosensitizer was developed, exhibiting potent phototoxicity and sensitivity to polarity changes.
The content of this RSS Feed (c) The Royal Society of Chemistry
A dual-functional photosensitizer was developed, exhibiting potent phototoxicity and sensitivity to polarity changes.
The content of this RSS Feed (c) The Royal Society of Chemistry
target
Chitosan-functionalized nanobubbles for precision oncology: advances in targeted cancer therapeutics
J. Mater. Chem. B, 2024, 12,11076-11088
DOI: 10.1039/D4TB01930J, Review Article
DOI: 10.1039/D4TB01930J, Review Article
Vivek Pandey, Tejasvi Pandey
The convergence of nanotechnology and cancer therapeutics has opened new frontiers in the development of advanced drug delivery systems.
The content of this RSS Feed (c) The Royal Society of Chemistry
The convergence of nanotechnology and cancer therapeutics has opened new frontiers in the development of advanced drug delivery systems.
The content of this RSS Feed (c) The Royal Society of Chemistry
target
Nanobiopolymers in cancer therapeutics: advancing targeted drug delivery through sustainable and controlled release mechanisms
J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB00599F, Review Article
DOI: 10.1039/D4TB00599F, Review Article
Shikha Gulati, Nabeela Ansari, Yamini Moriya, Kumud Joshi, Disha Prasad, Gargi Sajwan, Shefali Shukla, Sanjay Kumar, Rajender S. Varma
Nanobiopolymers in cancer therapeutics offer sustainable and targeted drug delivery with controlled release, enhancing treatment efficacy while ensuring sustainability and biodegradability for improved patient care.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry
Nanobiopolymers in cancer therapeutics offer sustainable and targeted drug delivery with controlled release, enhancing treatment efficacy while ensuring sustainability and biodegradability for improved patient care.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry
target
Lactobionic acid modified cobalt coordination polymer-coated peroxymonosulfate nanoparticles generate sulfate/hydroxy dual-radicals for targeted cancer therapy
J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01777C, Paper
DOI: 10.1039/D4TB01777C, Paper
Jiahui Li, Jiaxuan Li, Zelong Chen, Yichen Wan, Yi Wang, Zhichao Pei, Yuxin Pei
LCP NPs were prepared by forming a coordination polymer on peroxymonosulfate through the coordination between imidazole-2-carboxaldehyde and Co2+, then modified with lactobionic acid to improve the efficacy of sulfate/hydroxy dual-radical therapy.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry
LCP NPs were prepared by forming a coordination polymer on peroxymonosulfate through the coordination between imidazole-2-carboxaldehyde and Co2+, then modified with lactobionic acid to improve the efficacy of sulfate/hydroxy dual-radical therapy.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry
target
H2O2-activated mitochondria-targeting photosensitizer for fluorescence imaging-guided combination photodynamic and radiotherapy
J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01653J, Paper
DOI: 10.1039/D4TB01653J, Paper
Qiufen Tian, Zifan Zhu, Yun Feng, Shirui Zhao, Hui Lin, Wen Zhang, Zhiai Xu
Radiotherapy is a primary modality in cancer treatment but accompanied by severe side effects to healthy tissues and radiation resistance to some extent. To overcome these limitations, we developed a...
The content of this RSS Feed (c) The Royal Society of Chemistry
Radiotherapy is a primary modality in cancer treatment but accompanied by severe side effects to healthy tissues and radiation resistance to some extent. To overcome these limitations, we developed a...
The content of this RSS Feed (c) The Royal Society of Chemistry
target
Functionalities of pH-responsive DNA nanostructures in tumor-targeted strategies
J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01883D, Review Article
DOI: 10.1039/D4TB01883D, Review Article
Liyue Wen, Min Wang
Design and application of various pH-responsive DNA nanostructures for tumor-targeted strategies toward extracellular and intracellular environments are comprehensively reviewed. Their potential and challenges are also critically discussed.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry
Design and application of various pH-responsive DNA nanostructures for tumor-targeted strategies toward extracellular and intracellular environments are comprehensively reviewed. Their potential and challenges are also critically discussed.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry
target
Utilizing solid-state nanopore sensing for high-efficiency and precise targeted localization in antiviral drug development
Analyst, 2024, 149,5313-5319
DOI: 10.1039/D4AN00946K, Paper
DOI: 10.1039/D4AN00946K, Paper
Wei Xu, Lichun Zou, Haiyan Wang, Changhui Xu, Qinyang Fan, Jingjie Sha
The efficient identification and validation of drug targets are paramount in drug discovery and development.
The content of this RSS Feed (c) The Royal Society of Chemistry
The efficient identification and validation of drug targets are paramount in drug discovery and development.
The content of this RSS Feed (c) The Royal Society of Chemistry
target
Evaluating protocols for reproducible targeted metabolomics by NMR
Analyst, 2024, 149,5423-5432
DOI: 10.1039/D4AN01015A, Paper
DOI: 10.1039/D4AN01015A, Paper
Darcy Cochran, Panteleimon G. Takis, James L. Alexander, Benjamin H. Mullish, Nick Powell, Julian R. Marchesi, Robert Powers
Evaluating how sample preparation methods and data analysis platforms impact measured metabolite concentrations underscores the need for a universal consensus in the followed approaches for metabolomics data analysis.
The content of this RSS Feed (c) The Royal Society of Chemistry
Evaluating how sample preparation methods and data analysis platforms impact measured metabolite concentrations underscores the need for a universal consensus in the followed approaches for metabolomics data analysis.
The content of this RSS Feed (c) The Royal Society of Chemistry
target
In silico validation of allosteric inhibitors targeting Zika virus NS2B–NS3 protease
Phys. Chem. Chem. Phys., 2024, 26,27684-27693
DOI: 10.1039/D4CP02867H, Paper
DOI: 10.1039/D4CP02867H, Paper
Yeng-Tseng Wang, Yuan-Chin Hsieh, Tin-Yu Wu
The Zika virus (ZIKV), a member of the Flaviviridae family, poses a major threat to human health because of the lack of effective antiviral drugs.
The content of this RSS Feed (c) The Royal Society of Chemistry
The Zika virus (ZIKV), a member of the Flaviviridae family, poses a major threat to human health because of the lack of effective antiviral drugs.
The content of this RSS Feed (c) The Royal Society of Chemistry
target
Targeted protein degradation directly engaging lysosomes or proteasomes
Chem. Soc. Rev., 2024, 53,3253-3272
DOI: 10.1039/D3CS00344B, Tutorial Review
DOI: 10.1039/D3CS00344B, Tutorial Review
Open Access
This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.
Jiseong Kim, Insuk Byun, Do Young Kim, Hyunhi Joh, Hak Joong Kim, Min Jae Lee
This review delineates emerging technologies for targeted protein degradation that directly involve lysosomes or proteasomes. It explores their unique features, advantages, and limitations, offering perspectives on future therapeutic applications.
The content of this RSS Feed (c) The Royal Society of Chemistry
This review delineates emerging technologies for targeted protein degradation that directly involve lysosomes or proteasomes. It explores their unique features, advantages, and limitations, offering perspectives on future therapeutic applications.
The content of this RSS Feed (c) The Royal Society of Chemistry
target
Mitochondria-targeted BODIPY dyes for small molecule recognition, bio-imaging and photodynamic therapy
Chem. Soc. Rev., 2024, 53,3976-4019
DOI: 10.1039/D3CS00456B, Review Article
DOI: 10.1039/D3CS00456B, Review Article
Sisi Wang, Lizhi Gai, Yuncong Chen, Xiaobo Ji, Hua Lu, Zijian Guo
This review focuses on the design strategy, spectroscopic characteristics, and functionalization of mitochondrion-targeted BODIPY dyes, providing an overview of these dyes for mitochondrion-targeted bioimaging and photodynamic therapy.
The content of this RSS Feed (c) The Royal Society of Chemistry
This review focuses on the design strategy, spectroscopic characteristics, and functionalization of mitochondrion-targeted BODIPY dyes, providing an overview of these dyes for mitochondrion-targeted bioimaging and photodynamic therapy.
The content of this RSS Feed (c) The Royal Society of Chemistry
target
Mild boroxazolidone formation and dissociation: Application toward target identification of bioactive molecules
Chem. Commun., 2024, Accepted Manuscript
DOI: 10.1039/D4CC05370B, Communication
DOI: 10.1039/D4CC05370B, Communication
Toya Tabei, Kyoko Nagasawa-Goto, Yohei Saito
We successfully found that boroxazolidone can dissociate under aqueous conditions, which were applicable to a solution containing proteins. The immobilization of a newly synthesized diarylborinic acid on beads enabled the...
The content of this RSS Feed (c) The Royal Society of Chemistry
We successfully found that boroxazolidone can dissociate under aqueous conditions, which were applicable to a solution containing proteins. The immobilization of a newly synthesized diarylborinic acid on beads enabled the...
The content of this RSS Feed (c) The Royal Society of Chemistry
target
ARCaDia: Single-round screening of a DNA-type targeted covalent binder possessing a latent warhead
Chem. Commun., 2024, Accepted Manuscript
DOI: 10.1039/D4CC04594G, Communication
DOI: 10.1039/D4CC04594G, Communication
Open Access
This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.
Masumi Taki, Masayasu Kuwahara, Chaohui Li, Naoko Tomoda, Naoyuki Miyashita, Tetsuo Kan, Jay Yang
A covalent binder for a target protein was obtained by a direct single-round screening of a latent-warhead-modified DNA library via affinity/reactivity-based co-selection of aptameric deoxyribonucleic acid (ARCaDia), followed by a...
The content of this RSS Feed (c) The Royal Society of Chemistry
A covalent binder for a target protein was obtained by a direct single-round screening of a latent-warhead-modified DNA library via affinity/reactivity-based co-selection of aptameric deoxyribonucleic acid (ARCaDia), followed by a...
The content of this RSS Feed (c) The Royal Society of Chemistry
target
Tailoring of novel morpholine-sulphonamide linked thiazole moiety as dual targeting DHFR/DNA gyrase inhibitors: Synthesis, antimicrobial, antibiofilm activities and DFT with molecular modelling studies
New J. Chem., 2024, Accepted Manuscript
DOI: 10.1039/D3NJ05774G, Paper
DOI: 10.1039/D3NJ05774G, Paper
Moaz M. Abdou, Essam Eliwa, Mohamed Abdel Reheim, Ahmed Abu-Rayyan, Shimaa M. Abd El-Gilil, Mohammed Abu-Elghait , Mohamed H. Sharaf, Mohamed Kalaba, Ahmed Halawa, Walid Elgammal
Herein, the chemical synthesis of new thiazoles-based benzenesulfonamide-linked morpholine 4a,b–7 via late-stage thiazolation of the corresponding thiosemicarbazone 3 was reported. The skeletal formulas of the new compounds were confirmed by...
The content of this RSS Feed (c) The Royal Society of Chemistry
Herein, the chemical synthesis of new thiazoles-based benzenesulfonamide-linked morpholine 4a,b–7 via late-stage thiazolation of the corresponding thiosemicarbazone 3 was reported. The skeletal formulas of the new compounds were confirmed by...
The content of this RSS Feed (c) The Royal Society of Chemistry
target
Guanidine modification improves functions of natural RNA-targeting alkaloids
New J. Chem., 2024, Advance Article
DOI: 10.1039/D3NJ05833F, Communication
DOI: 10.1039/D3NJ05833F, Communication
Open Access
This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.
Tamaki Endoh, Sagar Satpathi, Yutong Chen, Saki Matsumoto, Tatsuya Ohyama, Peter Podbevšek, Janez Plavec, Kazumitsu Onizuka, Fumi Nagatsugi, Naoki Sugimoto
Guanidine modification on berberine improved RNA binding affinity and enhanced suppression of protein expression.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry
Guanidine modification on berberine improved RNA binding affinity and enhanced suppression of protein expression.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry
target
Govt 'in no hurry' on medium-term inflation target: Sources
Government would be comfortable if central bank took two years or longer to get inflation down to 4 per cent: Sources
target
India-Russia trade target of $100 bn realistic but urgent need for balance: Jaishankar
Russia’s First Deputy PM Denis Manturov begins two-day India visit, attends India-Russia Business Forum
target
Govt hopeful of meeting capital expenditure target for FY25
Big Push. Aims to meet ₹11.11 lakh crore capex target, may relax cash management norms in Jan-March quarter
target
TiE Global Summit 2024 targets ₹100 crore in funding for start-up initiative
The event will take place in Bangalore from December 9-11, 2024, and on December 12 in Mysore
target
Progress targets $1 billion revenue with acquisition; expands Bangalore team
The ShareFile business the company is acquiring generates approximately $240 million in revenue
target
Use of ionic liquids in amidation reactions for proteolysis targeting chimera synthesis
Org. Biomol. Chem., 2024, Advance Article
DOI: 10.1039/D4OB00304G, Paper
DOI: 10.1039/D4OB00304G, Paper
Michela Eleuteri, Jenny Desantis, Gabriele Cruciani, Raimondo Germani, Laura Goracci
Selective degradation of disease-causing proteins using proteolysis targeting chimeras (PROTACs) has gained great attention, thanks to its several advantages over traditional therapeutic modalities.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry
Selective degradation of disease-causing proteins using proteolysis targeting chimeras (PROTACs) has gained great attention, thanks to its several advantages over traditional therapeutic modalities.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry
target