target Development of Polymeric Aptamer Probes for In Vivo Continuous Precision Cancer Targeting By pubs.rsc.org Published On :: Mater. Chem. Front., 2024, Accepted ManuscriptDOI: 10.1039/D4QM00731J, Research ArticleSilin Huang, Yu-Ting He, Xiao-Jing Zhang, Xueqiang Wang, Qiang GuoAptamers, despite their specific targeting capabilities and widespread applications in various research domains, face a significant hurdle in biomedical research area due to their rapid degradation by nucleases. To address...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
target Correction: Enhancing the chemotherapeutic efficacy of platinum prodrug nanoparticles and inhibiting cancer metastasis by targeting iron homeostasis By pubs.rsc.org Published On :: Nanoscale Horiz., 2024, 9,2067-2068DOI: 10.1039/D4NH90069C, Correction Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Fang Ding, Lingpu Zhang, Hao Chen, Haiqin Song, Shiguo Chen, Haihua XiaoThe content of this RSS Feed (c) The Royal Society of Chemistry Full Article
target India close to finalising industry carbon targets ahead of Baku climate meet By www.thehindu.com Published On :: Thu, 24 Oct 2024 04:30:00 +0530 Numerically specifying the targets is a precursor to the setting up of a ‘compliance’ carbon market. This means that companies have to ensure that their carbon emissions intensity is within the specified limit or they must ‘buy’ credits from organisations that have surplus credits. Full Article Environment
target The climate targets of the world’s major oil and gas companies By www.thehindu.com Published On :: Wed, 13 Nov 2024 08:46:10 +0530 Direct comparisons of the oil companies’ climate plans are difficult as they emphasise different approaches to intensity-based targets Full Article Environment
target Targeted Cancer Therapies By www.cancer.gov Published On :: 2019-05-03 12:00:00 -0400 A fact sheet that describes targeted cancer therapies, which are drugs that interfere with specific molecules involved in cancer cell growth and survival. Full Article
target Harnessing DNA computing and nanopore decoding for practical applications: from informatics to microRNA-targeting diagnostics By pubs.rsc.org Published On :: Chem. Soc. Rev., 2024, Advance ArticleDOI: 10.1039/D3CS00396E, Tutorial Review Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Sotaro Takiguchi, Nanami Takeuchi, Vasily Shenshin, Guillaume Gines, Anthony J. Genot, Jeff Nivala, Yannick Rondelez, Ryuji KawanoThis tutorial review provides fundamentals on DNA computing and nanopore-based decoding, highlighting recent advances towards microRNA-targeting diagnostic applications.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
target Differential-targeting core-shell microneedle patch with coordinated and prolonged releases of mangiferin and MSC-derived exosomes for scarless skin regeneration By pubs.rsc.org Published On :: Mater. Horiz., 2024, Accepted ManuscriptDOI: 10.1039/D3MH01910A, CommunicationShang LYU, Qi Liu, Ho-Yin Yuen, Huizhi Xie, Yuhe Yang, Kelvin Yeung, Chak-Yin Tang, Shuqi Wang, Yaxiong Liu, Bin Li, Yong He, Xin ZhaoMicroneedles for skin regeneration are conventionally restricted by uncontrollable multi-drug release, limited types of drugs, and poor wound adhesion. Here, a novel core-shell microneedle patch is developed for scarless skin...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
target What Rule for the Federal Reserve? Forecast Targeting [electronic journal]. By encore.st-andrews.ac.uk Published On :: National Bureau of Economic Research Full Article
target Value for Money? Community Targeting in Vote-Buying and Politician Accountability [electronic journal]. By encore.st-andrews.ac.uk Published On :: National Bureau of Economic Research Full Article
target Tactical Target Date Funds [electronic journal]. By encore.st-andrews.ac.uk Published On :: Full Article
target Raising the Inflation Target: How Much Extra Room Does It Really Give? [electronic journal]. By encore.st-andrews.ac.uk Published On :: Full Article
target Price Level Targeting with Evolving Credibility [electronic journal]. By encore.st-andrews.ac.uk Published On :: Full Article
target Price Discrimination in the Information Age: Prices, Poaching, and Privacy with Personalized Targeted Discounts [electronic journal]. By encore.st-andrews.ac.uk Published On :: Full Article
target Price Customization and Targeting in Matching Markets [electronic journal]. By encore.st-andrews.ac.uk Published On :: Full Article
target The Optimal Inflation Target and the Natural Rate of Interest [electronic journal]. By encore.st-andrews.ac.uk Published On :: National Bureau of Economic Research Full Article
target M&A Activity and the Capital Structure of Target Firms [electronic journal]. By encore.st-andrews.ac.uk Published On :: Full Article
target Instrument-Based vs. Target-Based Rules [electronic journal]. By encore.st-andrews.ac.uk Published On :: National Bureau of Economic Research Full Article
target How well targeted are soda taxes? [electronic journal]. By encore.st-andrews.ac.uk Published On :: Full Article
target Hitting the Elusive Inflation Target [electronic journal]. By encore.st-andrews.ac.uk Published On :: National Bureau of Economic Research Full Article
target Filtered and Unfiltered Treatment Effects with Targeting Instruments [electronic journal]. By encore.st-andrews.ac.uk Published On :: Full Article
target The effect of gender-targeted transfers: Experimental Evidence from India [electronic journal]. By encore.st-andrews.ac.uk Published On :: Full Article
target Decentralized Targeting of Agricultural Credit Programs: Private versus Political Intermediaries [electronic journal]. By encore.st-andrews.ac.uk Published On :: National Bureau of Economic Research Full Article
target Dangers of a Double-Bottom Line: A Poverty Targeting Experiment Misses Both Targets [electronic journal]. By encore.st-andrews.ac.uk Published On :: National Bureau of Economic Research Full Article
target Building consensus: Shifting strategies in the territorial targeting of Turkey's public transport investment [electronic journal]. By encore.st-andrews.ac.uk Published On :: Full Article
target Average Inflation Targeting and the Interest Rate Lower Bound [electronic journal]. By encore.st-andrews.ac.uk Published On :: European Central Bank Full Article
target Government to extend UDAN scheme for 10 years, targets 350-400 airports by 2047 By www.thehindubusinessline.com Published On :: Mon, 21 Oct 2024 13:09:54 +0530 Since its launch in October 2016, the scheme has operationalised 601 routes and 71 airports, facilitating travel for over 1.44 crore passengers Full Article Logistics
target Skye Air intensifies quick-commerce partnerships, targets expansion to six cities within two years By www.thehindubusinessline.com Published On :: Mon, 21 Oct 2024 20:13:55 +0530 The firm focuses on delivering consignments within 10 minutes for quick-commerce clients and within four hours for e-commerce clients Full Article Logistics
target Air India Express targets a 50% yoy growth in passenger traffic for FY25 By www.thehindubusinessline.com Published On :: Sat, 09 Nov 2024 18:26:09 +0530 Air India Express’ Chief Executive Aloke Singh says that the airline will focus on growing its presence in the tier-II and III markets Full Article Logistics
target Collective effort needed to meet USD 2 trillion export target by 2030: Piyush Goyal By www.newkerala.com Published On :: Tue, 12 Nov 2024 17:12:02 +0530 Full Article
target Cyclic peptides targeting the SARS-CoV-2 programmed ribosomal frameshifting RNA from a multiplexed phage display library By pubs.rsc.org Published On :: Chem. Sci., 2024, Advance ArticleDOI: 10.1039/D4SC04026K, Edge Article Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Jacob A. Iannuzzelli, Rachel Bonn, Andrew S. Hong, Abhijith Saseendran Anitha, Jermaine L. Jenkins, Joseph E. Wedekind, Rudi FasanCyclopeptide agents targeted against the −1 programmed ribosomal frameshifting stimulatory sequence RNA pseudoknot of SARS-CoV-2 were discovered by screening a multiplexed phage display library of genetically encoded peptide macrocycles.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
target Triple-Function Porphyrin in Glycopolymeric Photosensitizer: From PhotoATRP to Targeted PDT By pubs.rsc.org Published On :: Chem. Sci., 2024, Accepted ManuscriptDOI: 10.1039/D4SC06466F, Edge Article Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Jiahui Lin, Zhiyuan Ma, Weiwei Zuo, Meifang ZhuPorphyrin derivatives serve as photocatalysts in reversible-deactivation radical polymerization and as photosensitizers in photodynamic therapy (PDT). Herein, a triple function porphyrin, ZnTPPC6Br, was synthesized as photocatalyst and initiator for photoATRP....The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
target Combination targeted treatment produces lasting remissions in people with resistant aggressive B-cell lymphoma By www.cancer.gov Published On :: Wed, 19 Jun 2024 12:00:00 +0000 More than half of clinical trial participants treated with venetoclax, ibrutinib, prednisone, obinutuzumab, and lenalidomide (ViPOR) had substantial tumor shrinkage. Of those, 38% had tumors that disappeared completely. Full Article
target Injury is fine now, next big target is 2025 World Championship: Neeraj Chopra By www.thehindu.com Published On :: Fri, 27 Sep 2024 12:21:26 +0530 Neeraj Chopra battled an adductor muscle niggle throughout the year and it also affected his performance at both the Olympics and the DL finale, where he also competed with a fractured left hand Full Article Other Sports
target Iranian charged for plotting Trump assassination tasked with targeting Israeli tourists in Sri Lanka: U.S authority By www.thehindu.com Published On :: Sun, 10 Nov 2024 10:32:43 +0530 Shakeri is an Islamic Revolutionary Guard Corps (IRGC) asset, remains at large and is believed to reside in Tehran, Iran Full Article World
target JSP targets Roja over Tirumala darshan tickets ‘scam’ By www.thehindu.com Published On :: Thu, 07 Nov 2024 19:48:21 +0530 Full Article Andhra Pradesh
target A novel ratiometric sensor for fluorimetric and visual dual-mode detection of Al3+ in environmental water based on the target-regulated formation of Eu MOFs By pubs.rsc.org Published On :: Anal. Methods, 2024, Advance ArticleDOI: 10.1039/D4AY00324A, PaperTao-Li Chen, Xiang-Juan Kong, Xin-Xin Dong, Zhi-Jie Mao, Fang-Fang Kong, Qiang XiaoThe illustration of the ratiometric sensor for fluorimetric (A) and visual detection (B) of Al3+.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
target A comprehensive HRMS methodology using LC-(ESI)-/GC-(APCI)-QTOF MS complementary platforms for wide-scope target screening of >750 pesticides in olive oil By pubs.rsc.org Published On :: Anal. Methods, 2024, Advance ArticleDOI: 10.1039/D4AY00181H, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Sofia K. Drakopoulou, Stefanos E. Kokolakis, Apostolos L. Karagiannidis, Marilena E. Dasenaki, Niki C. Maragou, Nikolaos S. ThomaidisThis study presents a robust and validated HRMS method for the determination of 771 pesticides in olive oil. LC-ESI/GC-APCI-QTOF MS was employed for the analysis.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
target Design, synthesis, inhibitory activity, and molecular simulations study for D-glucose-conjugated thioureas containing pyrimidine ring as multitarget inhibitors against α-amylase, α-glucosidase, DDP-4, and PTP1B in Type 2 diabetes mellitus By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3395-3417DOI: 10.1039/D4MD00334A, Research ArticleVu Ngoc Toan, Do Son Hai, Hoang Thi Kim Van, Nguyen Minh Tri, Duong Ngoc Toan, Nguyen Thi Thanh Mai, Nguyen Dinh ThanhD-Glucose-conjugated thioureas from 2-aminopyrimidines had inhibitory activity against α-amylase, α-glucosidase, DPP-4, PTP1B. The cytotoxicity, inhibitory kinetics, and molecular simulations of the most potent inhibitors 8k, 8j, 8f, and 8h were studied.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
target A novel, glutathione-activated prodrug of pimasertib loaded in liposomes for targeted cancer therapy By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00517A, Research Article Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Arianna Amenta, Susanna Comi, Marcelo Kravicz, Silvia Sesana, Antonia Antoniou, Daniele Passarella, Pierfausto Seneci, Sara Pellegrino, Francesca ReA novel, glutathione-activated prodrug of pimasertib (PROPIMA) has been developed. PROPIMA showed ability to inhibit tumour cell migration and proliferation controlled over time, while also achieving a high incorporation rate into liposomes.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
target Amides of moronic acid and morolic acid with the tripeptides MAG and GAM targeting antimicrobial, antiviral and cytotoxic effects By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4MD00742E, Research Article Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Uladzimir Bildziukevich, Lucie Cerna, Jana Trylčová, Marie Kvasnicova, Lucie Rárová, David Šaman, Petra Lovecká, Jan Weber, Zdenek WimmerA series of amides of the selected plant triterpenoids, moronic acid and morolic acid, with the tripeptides MAG and GAM was designed and synthesized. Two required tripeptides 5 and 10...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
target Azo derivatives of monoterpenes as anti-Helicobacter pylori agents: from synthesis to structure-based target investigation By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00511B, Research Article Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Francesco Melfi, Marialuigia Fantacuzzi, Simone Carradori, Ilaria D'Agostino, Alessandra Ammazzalorso, Noemi Mencarelli, Marialucia Gallorini, Mattia Spano, Paolo Guglielmi, Mariangela Agamennone, Sazan Haji Ali, Ali Al-Samydai, Francesca SistoMonoterpene-derived azo benzenes showed selective antibacterial activity against Helicobacter pylori with a safe profile. An in silico investigation highlighted the inosine 5'-monophosphate dehydrogenase enzyme as the putative target.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
target Set daily targets By www.thehindu.com Published On :: Sat, 09 Nov 2024 15:00:00 +0530 Uncertain about your career options? Low on self-confidence? This column may help Full Article Education
target Design, synthesis, and in vitro and in vivo biological evaluation of triazolopyrimidine hybrids as multitarget directed anticancer agents By pubs.rsc.org Published On :: RSC Adv., 2024, 14,35239-35254DOI: 10.1039/D4RA06704E, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Heba A. Adawy, Samar S. Tawfik, Abdullah A. Elgazar, Khalid B. Selim, Fatma E. GodaIn response to the urgent need for new anti-proliferative agents, four novel series of triazolopyrimidine compounds (7a–e, 9a–d, 11a–f, and 13a–e) were synthesized and evaluated for in vitro and in vivo anticancer efficacy.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
target Is there a scientific reason why online phishing fraudsters target senior citizens? By www.thehindu.com Published On :: Tue, 12 Nov 2024 16:52:27 +0530 A research paper documents the fact that older people tend to underestimate their cognitive decline and this could affect their finances; experts say senior citizens could be more vulnerable to cyber scamsters and to financial abuse from their own families Full Article Health
target Israel hits 40,000 Hamas targets in Gaza after one year of conflict By www.thehindubusinessline.com Published On :: Mon, 07 Oct 2024 09:25:20 +0530 More than 100 hostages remain held by Hamas Full Article World
target Israel-Iran tensions escalate: Retaliatory strikes target military installations in Tehran By www.thehindubusinessline.com Published On :: Sat, 26 Oct 2024 07:10:55 +0530 The Israeli military cited continuous Iranian attacks from multiple fronts since October 7, affirming Israel’s right to retaliate Full Article World
target Vinicius, Mbappe on target as Madrid crush plucky Espanyol By www.thehindu.com Published On :: Mon, 23 Sep 2024 02:05:34 +0530 The comprehensive victory was Madrid's 38th consecutive La Liga game without defeat, their last loss in the competition coming just under a year ago, against Atletico Madrid in September 2023 Full Article Football
target Multi-functional biotinylated platinum(IV)–SAHA conjugate for tumor-targeted chemotherapy By pubs.rsc.org Published On :: Dalton Trans., 2024, 53,17829-17840DOI: 10.1039/D4DT01571A, PaperAjay Gupta, Pijus K. SasmalHerein, we have developed a hydrolytically stable biotinylated Pt(IV) complex conjugated with a histone deacetylase inhibitor (SAHA) as a multi-functional tumour targeted chemotherapeutic agent.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
target Vizhinjam poised to clock half a million cargo throughput this FY, eight times higher than targeted volume By www.thehindu.com Published On :: Sun, 10 Nov 2024 21:16:08 +0530 While the initial projection for Phase I was 1 to 1.5 million cargo units per annum, the seaport has already handled 1.08 lakh cargo units – just three months into the trial run period Full Article Kerala
