independent Why Instructional Coaching Matters in Independent Schools By feedproxy.google.com Published On :: Tue, 03 Apr 2018 00:00:00 +0000 While independent schools can feel quite different from their public, charter, and parochial counterparts, the glue that holds all schools together is this noble charge we call teaching. Full Article Specific+populations
independent 'Walls That Talk' Give Students Tools for Writing Independently (Video) By feedproxy.google.com Published On :: Wed, 26 Sep 2018 00:00:00 +0000 High school teacher Kateryna Haggerty explains how visual aids in her classroom help her English-language learner students write more confidently. Full Article Englishlanguagelearners
independent Independent Living and Romantic Relations Among Young Adults Born Preterm By pediatrics.aappublications.org Published On :: 2015-01-26T00:05:28-08:00 Adults born very preterm or with very low birth weight have a lower likelihood of leaving their childhood home, and starting romantic relationships, and are older when experiencing first intercourse or having their first child than their term-born peers.Compared with term-born individuals, those born preterm perceived themselves less attractive and were less likely to have cohabited or experienced first-time sexual intercourse by young adulthood. This outcome indicates that social outcomes are different among preterm-born individuals. (Read the full article) Full Article
independent Stp1 loss of function promotes {beta}-lactam resistance in S. aureus that is independent of classical genes [Mechanisms of Resistance] By aac.asm.org Published On :: 2020-03-16T08:17:37-07:00 β-lactam resistance in Staphylococcus aureus limits treatment options. Stp1 and Stk1, a serine-threonine phosphatase and kinase respectively, mediate serine-threonine kinase (STK) signaling. Loss of function point mutations in stp1 were detected among laboratory passaged, β-lactam resistant S. aureus strains lacking mecA and blaZ, the major determinants of β-lactam resistance in the bacteria. Loss of Stp1 function facilitates β-lactam resistance of the bacteria. Full Article
independent Independent Thought v Union of India and Ors. (2017) By www.lawyersclubindia.com Published On :: Fri, 1 May 2020 10:48:24 GMT Independent Thought v Union of India and Ors. (2017) Full Article
independent DOL Releases Guidance for Independent Contractors and Self-employed Seeking Unemployment Through the CARES Act By news.delaware.gov Published On :: Thu, 16 Apr 2020 14:51:44 +0000 The Coronavirus Aid, Relief, and Economic Security (CARES) Act recently passed by the United States Congress and signed into law on March 27th provides unemployment assistance to independent contractors and those self-employed who have been affected by the Coronavirus. Full Article Department of Labor benefits Coronavirus Delaware Department of Labor Division of Unemployment Insurance unemployment insurance benefits
independent US attempts to push Covid-19 China lab theory undermine plan for independent probe into virus' origin – reports By www.rt.com Published On :: Fri, 08 May 2020 15:26:55 +0000 The push for a comprehensive inquiry into the origin of the novel coronavirus is being hampered by the US narrative that Covid-19 may have stemmed from a lab in China, Australian diplomatic and intelligence sources told Reuters. Read Full Article at RT.com Full Article
independent Tax credits for independent energy storage projects introduced in US congress By feedproxy.google.com Published On :: 2019-04-05T17:49:31Z On Thursday, US Congressman from Pennsylvania Mike Doyle introduced a bill that would establish a federal investment tax credit (ITC) for energy storage. The legislation would allow energy storage project developers, both commercial and residential, to receive a 30 percent tax credit for large-scale, commercial-scale and residential-scale storage projects through 2021. Full Article Storage Policy News
independent Independent cinema campaign meets donation goal By www.japantimes.co.jp Published On :: Thu, 30 Apr 2020 20:50:31 +0900 A crowdfunding campaign to save art houses reaches its donation goal as Japan's film industry grapples with the effects of the COVID-19 outbreak. Full Article Culture Japanese film crowdfunding cinemas covid-19 covid-19 in Japan
independent China and Australia brawl over call for independent investigation of COVID-19 origins By globalvoices.org Published On :: Mon, 04 May 2020 09:01:29 +0000 'Australia is “gum stuck to the bottom of China’s shoe”, huh? Ok, well, it’s time for Australia to rethink trade and other agreements with China if they don’t like criticism' Full Article Australia China COVID-19 East Asia Economics & Business English Feature Health International Relations Oceania Politics Weblog
independent The Absence of (p)ppGpp Renders Initiation of Escherichia coli Chromosomal DNA Synthesis Independent of Growth Rates By mbio.asm.org Published On :: 2020-03-10T01:30:42-07:00 ABSTRACT The initiation of Escherichia coli chromosomal DNA replication starts with the oligomerization of the DnaA protein at repeat sequences within the origin (ori) region. The amount of ori DNA per cell directly correlates with the growth rate. During fast growth, the cell generation time is shorter than the time required for complete DNA replication; therefore, overlapping rounds of chromosome replication are required. Under these circumstances, the ori region DNA abundance exceeds the DNA abundance in the termination (ter) region. Here, high ori/ter ratios are found to persist in (p)ppGpp-deficient [(p)ppGpp0] cells over a wide range of balanced exponential growth rates determined by medium composition. Evidently, (p)ppGpp is necessary to maintain the usual correlation of slow DNA replication initiation with a low growth rate. Conversely, ori/ter ratios are lowered when cell growth is slowed by incrementally increasing even low constitutive basal levels of (p)ppGpp without stress, as if (p)ppGpp alone is sufficient for this response. There are several previous reports of (p)ppGpp inhibition of chromosomal DNA synthesis initiation that occurs with very high levels of (p)ppGpp that stop growth, as during the stringent starvation response or during serine hydroxamate treatment. This work suggests that low physiological levels of (p)ppGpp have significant functions in growing cells without stress through a mechanism involving negative supercoiling, which is likely mediated by (p)ppGpp regulation of DNA gyrase. IMPORTANCE Bacterial cells regulate their own chromosomal DNA synthesis and cell division depending on the growth conditions, producing more DNA when growing in nutritionally rich media than in poor media (i.e., human gut versus water reservoir). The accumulation of the nucleotide analog (p)ppGpp is usually viewed as serving to warn cells of impending peril due to otherwise lethal sources of stress, which stops growth and inhibits DNA, RNA, and protein synthesis. This work importantly finds that small physiological changes in (p)ppGpp basal levels associated with slow balanced exponential growth incrementally inhibit the intricate process of initiation of chromosomal DNA synthesis. Without (p)ppGpp, initiations mimic the high rates present during fast growth. Here, we report that the effect of (p)ppGpp may be due to the regulation of the expression of gyrase, an important enzyme for the replication of DNA that is a current target of several antibiotics. Full Article
independent NRF3-POMP-20S Proteasome Assembly Axis Promotes Cancer Development via Ubiquitin-Independent Proteolysis of p53 and Retinoblastoma Protein [Research Article] By mcb.asm.org Published On :: 2020-04-28T08:00:17-07:00 Proteasomes are essential protease complexes that maintain cellular homeostasis, and aberrant proteasomal activity supports cancer development. The regulatory mechanisms and biological function of the ubiquitin-26S proteasome have been studied extensively, while those of the ubiquitin-independent 20S proteasome system remain obscure. Here, we show that the cap ’n’ collar (CNC) family transcription factor NRF3 specifically enhances 20S proteasome assembly in cancer cells and that 20S proteasomes contribute to colorectal cancer development through ubiquitin-independent proteolysis of the tumor suppressor p53 and retinoblastoma (Rb) proteins. The NRF3 gene is highly expressed in many cancer tissues and cell lines and is important for cancer cell growth. In cancer cells, NRF3 upregulates the assembly of the 20S proteasome by directly inducing the gene expression of the 20S proteasome maturation protein POMP. Interestingly, NRF3 knockdown not only increases p53 and Rb protein levels but also increases p53 activities for tumor suppression, including cell cycle arrest and induction of apoptosis. Furthermore, protein stability and cell viability assays using two distinct proteasome inhibitor anticancer drugs, the 20S proteasome inhibitor bortezomib and the ubiquitin-activating enzyme E1 inhibitor TAK-243, show that the upregulation of the NRF3-POMP axis leads to ubiquitin-independent proteolysis of p53 and Rb and to impaired sensitivity to bortezomib but not TAK-243. More importantly, the NRF3-POMP axis supports tumorigenesis and metastasis, with higher NRF3/POMP expression levels correlating with poor prognoses in patients with colorectal or rectal adenocarcinoma. These results suggest that the NRF3-POMP-20S proteasome assembly axis is significant for cancer development via ubiquitin-independent proteolysis of tumor suppressor proteins. Full Article
independent Establishment of 5'-3' interactions in mRNA independent of a continuous ribose-phosphate backbone [ARTICLE] By rnajournal.cshlp.org Published On :: 2020-04-16T06:30:22-07:00 Functions of eukaryotic mRNAs are characterized by intramolecular interactions between their ends. We have addressed the question whether 5' and 3' ends meet by diffusion-controlled encounter "through solution" or by a mechanism involving the RNA backbone. For this purpose, we used a translation system derived from Drosophila embryos that displays two types of 5'–3' interactions: Cap-dependent translation initiation is stimulated by the poly(A) tail and inhibited by Smaug recognition elements (SREs) in the 3' UTR. Chimeric RNAs were made consisting of one RNA molecule carrying a luciferase coding sequence and a second molecule containing SREs and a poly(A) tail; the two were connected via a protein linker. The poly(A) tail stimulated translation of such chimeras even when disruption of the RNA backbone was combined with an inversion of the 5'–3' polarity between the open reading frame and poly(A) segment. Stimulation by the poly(A) tail also decreased with increasing RNA length. Both observations suggest that contacts between the poly(A) tail and the 5' end are established through solution, independently of the RNA backbone. In the same chimeric constructs, SRE-dependent inhibition of translation was also insensitive to disruption of the RNA backbone. Thus, tracking of the backbone is not involved in the repression of cap-dependent initiation. However, SRE-dependent repression was insensitive to mRNA length, suggesting that the contact between the SREs in the 3' UTR and the 5' end of the RNA might be established in a manner that differs from the contact between the poly(A) tail and the cap. Full Article
independent Inflammatory and mitogenic signals drive interleukin 23 subunit alpha (IL23A) secretion independent of IL12B in intestinal epithelial cells [Signal Transduction] By www.jbc.org Published On :: 2020-05-08T03:41:14-07:00 The heterodimeric cytokine interleukin-23 (IL-23 or IL23A/IL12B) is produced by dendritic cells and macrophages and promotes the proinflammatory and regenerative activities of T helper 17 (Th17) and innate lymphoid cells. A recent study has reported that IL-23 is also secreted by lung adenoma cells and generates an inflammatory and immune-suppressed stroma. Here, we observed that proinflammatory tumor necrosis factor (TNF)/NF-κB and mitogen-activated protein kinase (MAPK) signaling strongly induce IL23A expression in intestinal epithelial cells. Moreover, we identified a strong crosstalk between the NF-κB and MAPK/ERK kinase (MEK) pathways, involving the formation of a transcriptional enhancer complex consisting of proto-oncogene c-Jun (c-Jun), RELA proto-oncogene NF-κB subunit (RelA), RUNX family transcription factor 1 (RUNX1), and RUNX3. Collectively, these proteins induced IL23A secretion, confirmed by immunoprecipitation of endogenous IL23A from activated human colorectal cancer (CRC) cell culture supernatants. Interestingly, IL23A was likely secreted in a noncanonical form, as it was not detected by an ELISA specific for heterodimeric IL-23 likely because IL12B expression is absent in CRC cells. Given recent evidence that IL23A promotes tumor formation, we evaluated the efficacy of MAPK/NF-κB inhibitors in attenuating IL23A expression and found that the MEK inhibitor trametinib and BAY 11–7082 (an IKKα/IκB inhibitor) effectively inhibited IL23A in a subset of human CRC lines with mutant KRAS or BRAFV600E mutations. Together, these results indicate that proinflammatory and mitogenic signals dynamically regulate IL23A in epithelial cells. They further reveal its secretion in a noncanonical form independent of IL12B and that small-molecule inhibitors can attenuate IL23A secretion. Full Article
independent The Transcriptional Aftermath in Two Independently Formed Hybrids of the Opportunistic Pathogen Candida orthopsilosis By msphere.asm.org Published On :: 2020-05-06T07:29:31-07:00 ABSTRACT Interspecific hybridization can drive evolutionary adaptation to novel environments. The Saccharomycotina clade of budding yeasts includes many hybrid lineages, and hybridization has been proposed as a source for new pathogenic species. Candida orthopsilosis is an emerging opportunistic pathogen for which most clinical isolates are hybrids, each derived from one of at least four independent crosses between the same two parental lineages. To gain insight into the transcriptomic aftermath of hybridization in these pathogens, we analyzed allele-specific gene expression in two independently formed hybrid strains and in a homozygous strain representative of one parental lineage. Our results show that the effect of hybridization on overall gene expression is rather limited, affecting ~4% of the genes studied. However, we identified a larger effect in terms of imbalanced allelic expression, affecting ~9.5% of the heterozygous genes in the hybrids. This effect was larger in the hybrid with more extensive loss of heterozygosity, which may indicate a tendency to avoid loss of heterozygosity in these genes. Consistently, the number of shared genes with allele-specific expression in the two independently formed hybrids was higher than random expectation, suggesting selective retention. Some of the imbalanced genes have functions related to pathogenicity, including zinc transport and superoxide dismutase activities. While it remains unclear whether the observed imbalanced genes play a role in virulence, our results suggest that differences in allele-specific expression may add an additional layer of phenotypic plasticity to traits related to virulence in C. orthopsilosis hybrids. IMPORTANCE How new pathogens emerge is an important question that remains largely unanswered. Some emerging yeast pathogens are hybrids originated through the crossing of two different species, but how hybridization contributes to higher virulence is unclear. Here, we show that hybrids selectively retain gene regulation plasticity inherited from the two parents and that this plasticity affects genes involved in virulence. Full Article
independent Plasma S100A8/A9 Concentrations and Clinical Outcomes of Ischemic Stroke in 2 Independent Multicenter Cohorts By academic.oup.com Published On :: Tue, 14 Apr 2020 00:00:00 GMT AbstractBackgroundS100A8/A9 is implicated in inflammation mechanisms related to atherosclerosis and plaque vulnerability, but it remains unclear whether S100A8/A9 is associated with the prognosis of ischemic stroke. The aim of this study was to investigate these associations in 2 independent multicenter cohorts.MethodsPlasma S100A8/A9 concentrations at baseline were measured among 4785 patients with ischemic stroke from 2 independent cohorts: Infectious Factors, Inflammatory Markers, and Prognosis of Acute Ischemic Stroke (IIPAIS) and China Antihypertensive Trial in Acute Ischemic Stroke (CATIS). The primary outcome was a composite outcome of death or major disability at 3 months after ischemic stroke. Secondary outcomes were major disability, death, and a composite outcome of death or vascular events.ResultsAmong the combined participants of IIPAIS and CATIS, the adjusted odds ratios associated with the highest quartile of plasma S100A8/A9 were 2.11 (95% CI, 1.66–2.68) for the primary outcome and 1.62 (95% CI, 1.27–2.07) for the secondary outcome of major disability; adjusted hazard ratios were 4.14 (95% CI, 2.10–8.15) for the secondary outcome of death and 2.08 (95% CI, 1.38–3.13) for the composite outcome of death or vascular events. Each SD increase of log-transformed S100A8/A9 was associated with 28% (95% CI, 18%–39%; P < 0.001) increased risk of the primary outcome. Multivariable-adjusted spline regression analyses showed a linear association between plasma S100A8/A9 concentrations and primary outcome (P < 0.001 for linearity). Subgroup analyses further confirmed these associations.ConclusionsHigh plasma S100A8/A9 concentrations at baseline were independently associated with increased risks of adverse clinical outcomes at 3 months after ischemic stroke, suggesting that S100A8/A9 might have a role as a prognostic marker of ischemic stroke. Full Article
independent Independent shops 'will struggle to open again after lockdown without loans' By www.standard.co.uk Published On :: 2020-04-16T10:18:00Z The Government was today warned that up to a third of independent shops will be unable to reopen when the lockdown lifts after facing "horrible" delays in accessing emergency government loans. Full Article
independent Australia We're Full Party or an Independent? Who will win the Eden-Monaro by-election? | First Dog on the Moon By www.theguardian.com Published On :: 2020-05-08T05:34:40Z Is it all moot because of the deadly virus infecting Australia and no I don’t mean the National party ahahahaSign up here to get an email whenever First Dog cartoons are publishedGet all your needs met at the First Dog shop if what you need is First Dog merchandise and prints Continue reading... Full Article Australian politics NSW south coast Liberal party Labor party Australia news
independent Best independent online wine delivery in London By www.standard.co.uk Published On :: 2020-03-28T14:54:00Z London's wine shops and bars have shifted their booze online to beat the crippling financial effects of coronavirus. Abbie Moulton on the new way to drink responsibly... Full Article
independent Australia calls for independent study of wet market risks in response to COVID-19 pandemic By www.abc.net.au Published On :: Thu, 23 Apr 2020 01:16:08 +1000 Australia is ratcheting up pressure on China to look into the health risks associated with wildlife wet markets as the world continues to battle the deadly spread of the coronavirus pandemic. Full Article Agricultural Policy Federal Government Government and Politics International Aid and Trade Agricultural Marketing Markets Business Economics and Finance Trade Agribusiness
independent Victoria criticises 'completely inappropriate' independent schools funding offer from Federal Government By www.abc.net.au Published On :: Wed, 29 Apr 2020 10:09:12 +1000 Victorian Education Minister James Merlino accuses the Federal Government of using funding to "force" independent schools to undermine the state's strategy on face-to-face learning during the coronavirus pandemic. Full Article COVID-19 Diseases and Disorders Health Respiratory Diseases Business Economics and Finance Work Community and Society States and Territories State of Emergency Government and Politics
independent Independent senator defects to the Progressives as senators spar over committee seats By www.cbc.ca Published On :: Fri, 8 May 2020 15:40:13 EDT Manitoba Sen. Patricia Bovey has left the Independent Senators Group (ISG) and will now sit as a member of the Progressive caucus, a group composed of former Liberal senators. Full Article News/Politics
independent Dallas Independent School District Agrees to Settle False Claims Allegations Involving E-Rate Program By www.justice.gov Published On :: Fri, 26 Jun 2009 10:13:59 EDT The Dallas Independent School District (DISD) has agreed to settle claims that the school district violated the False Claims Act in connection with the Federal Communications Commissions E-Rate program. Under the terms of the settlement, the DISD will relinquish more than $150 million in requests for federal funds, and will pay a total of $750,000. Full Article OPA Press Releases
independent Houston Independent School District Agrees to Settle False Claims Allegations Involving the E-rate Program By www.justice.gov Published On :: Mon, 8 Mar 2010 16:51:36 EST The Houston Independent School District has agreed to relinquish millions of dollars in requests for federal funds and to pay a total of $850,000 as part of a civil settlement relating to allegations that the school district violated the False Claims Act in connection with the Federal Communications Commission’s (FCC) E-Rate program. Full Article OPA Press Releases
independent Assistant Attorney General Lanny A. Breuer of the Criminal Division Speaks at the 3rd Russia and Commonwealth of Independent States Summit on Anti-corruption By www.justice.gov Published On :: Wed, 16 Mar 2011 10:08:57 EDT "This conference comes at an important moment in Russia’s efforts to strengthen its rule of law. In the Justice Department, we have long recognized corruption as a transnational problem. Corruption affects countries rich and poor, large and small, and it has particularly harmful effects on emerging economies." Full Article Speech
independent Independent Contractor in Afghanistan Pleads Guilty for His Role in Offering $54,000 in Bribes to a U.S. Government Official By www.justice.gov Published On :: Fri, 14 Feb 2014 16:15:11 EST Earlier today at the federal courthouse in Brooklyn, N.Y., Akbar Ahmad Sherzai, 49, of Centreville, Va., an independent contractor for a trucking company operating in Afghanistan that was responsible for delivering fuel to U.S. Army installations, pleaded guilty to his role in offering a U.S. Army serviceman $54,000 in bribes to falsify documents. Full Article OPA Press Releases
independent Single cell and tissue-transcriptomic analysis of murine bladders reveals age- and TNFα-dependent but microbiota-independent tertiary lymphoid tissue formation By feeds.nature.com Published On :: 2020-05-04 Full Article
independent CMV-independent increase in CD27−CD28+ CD8+ EMRA T cells is inversely related to mortality in octogenarians By feeds.nature.com Published On :: 2020-01-21 Full Article
independent Author Correction: “Dysfunctions” induced by Roux-en-Y gastric bypass surgery are concomitant with metabolic improvement independent of weight loss By feeds.nature.com Published On :: 2020-04-28 Full Article
independent Placental expression of leptin: fetal sex-independent relation with human placental growth By feeds.nature.com Published On :: 2020-05-07 Full Article
independent Arizona State Legislature v. Arizona Independent Redistricting Commission, et al. By webfeeds.brookings.edu Published On :: Mon, 29 Jun 2015 13:45:00 -0400 Editor's Note: For full disclosure, Tom Mann (joined by Norm Ornstein) filed an amicus curiae brief in Arizona State Legislature v. Arizona Independent Redistricting Commission. James Madison would be pleased. The 5-4 decision announced today by the Supreme Court upholding Arizona’s use of the initiative to establish an independent redistricting commission is a model of constitutional reasoning and statutory interpretation. It underscores the essential connection between republican government and popular sovereignty, in which the people have the ultimate authority over who shall represent them in public office. The majority opinion quotes Madison to powerful effect: “The genius of republican liberty seems to demand . . . not only that all power should be derived from the people, but those entrusted with it should be kept in dependence on the people.” Madison worried about the dangers of the manipulation of electoral rules to serve the immediate interests of political actors. He was himself the target of a gerrymander designed (unsuccessfully) to deny him a seat in the first Congress. The Elections Clause of the Constitution, by granting Congress the power to override state actions setting the time, place and manner of elections, was designed partly as a safety valve to contain the abuse of power by those in a position to determine which voters will hold them accountable. Today’s intensely polarized politics drive major partisan campaigns to seize control of the redistricting authority in the states and to wield that power to boost prospects for majority standing in the House. Partisan gerrymandering is not the major source of our dysfunctional politics but it surely reinforces and exacerbates the tribal wars between the parties. A number of states have used the initiative device provided in their constitutions to establish independent commissions to replace or supplement the regular state legislative process in redrawing congressional and/or state legislative district boundaries. Such commissions are no panacea for partisan gerrymandering. Their composition and rules vary in ways that can shape the outcome. But the evidence suggests they can mitigate the conflicts of interest that are a part of the regular process and produce more timely plans less subject to judicial preemption. The Court has upheld the right of those states to legislate electoral rules through a popular vote. Had the minority position prevailed, state laws governing many aspects of the electoral process would have been subject to constitutional challenge. And an important safety value available to the people of the states for responding to abuses of power by those in public office has been preserved. This should not be read more broadly as a triumph of direct democracy over representative government. Many scholars who provided expert opinion supporting the majority opinion retain serious concerns about the overuse and misuse of initiatives and referendums. Instead, the decision strengthens the legitimacy of representative democracy by reinforcing the essential link between republican government and popular sovereignty. Authors Thomas E. Mann Image Source: © Jonathan Ernst / Reuters Full Article
independent A proposal for modernizing labor laws for 21st century work: The “independent worker” By webfeeds.brookings.edu Published On :: Tue, 08 Dec 2015 00:00:00 -0500 Abstract New and emerging work relationships arising in the “online gig economy” do not fit easily into the existing legal definitions of “employee” and “independent contractor” status. The distinction is important because employees qualify for a range of legally mandated benefits and protections that are not available to independent contractors, such as the right to organize and bargain collectively, workers’ compensation insurance coverage, and overtime compensation. This paper proposes a new legal category, which we call “independent workers,” for those who occupy the gray area between employees and independent contractors. Independent workers typically work with intermediaries who match workers to customers. The independent worker and the intermediary have some elements of the arms-length independent business relationships that characterize “independent contractor” status, and some elements of a traditional employee-employer relationship. On the one hand, independent workers have the ability to choose when to work, and whether to work at all. They may work with multiple intermediaries simultaneously, or conduct personal tasks while they are working with an intermediary. It is thus impossible in many circumstances to attribute independent workers’ work hours to any employer. In this critical respect, independent workers are similar to independent businesses. On the other hand, the intermediary retains some control over the way independent workers perform their work, such as by setting their fees or fee caps, and they may “fire” workers by prohibiting them from using their service. In these respects, independent workers are similar to traditional employees. Evidence is presented suggesting that about 600,000 workers, or 0.4 percent of total U.S. employment, work with an online intermediary in the gig economy. Although there are probably many more workers who currently work with an offline intermediary who would qualify for independent worker status than there are who work with an online intermediary, the number of workers participating in the online gig economy is growing very rapidly. In our proposal, independent workers — regardless of whether they work through an online or offline intermediary — would qualify for many, although not all, of the benefits and protections that employees receive, including the freedom to organize and collectively bargain, civil rights protections, tax withholding, and employer contributions for payroll taxes. Because it is conceptually impossible to attribute their work hours to any single intermediary, however, independent workers would not qualify for hours-based benefits, including overtime or minimum wage requirements. Further, because independent workers would rarely, if ever, qualify for unemployment insurance benefits given the discretion they have to choose whether to work through an intermediary, they would not be covered by the program or be required to contribute taxes to fund that program. However, intermediaries would be permitted to pool independent workers for purposes of purchasing and providing insurance and other benefits at lower cost and higher quality without the risk that their relationship will be transformed into an employment relationship. Our proposal seeks to structure benefits to make independent worker status neutral when compared with employee status, as well as to enhance the efficiency of the operation of the labor market. By extending many of the legal benefits and protections found in employment relationships to independent workers, our proposal would protect and extend the social compact between workers and employers, and reduce the legal uncertainty and legal costs that currently beset many independent worker relationships. Downloads Download the policy brief Authors Seth D. HarrisAlan B. Krueger Publication: The Hamilton Project Full Article
independent Keep independent Israeli action on the table By webfeeds.brookings.edu Published On :: Fri, 18 Mar 2016 12:15:00 -0400 While Israeli and Palestinian interests are best served by a negotiated two-state state solution, the peace plan that Sam Bahour proposed in his February post disregards Israel's demographic and security concerns and is tantamount to a Palestinian veto on a negotiated solution. His insistence on the right of return for Palestinian refugees and rejection of security limitations on Palestinian sovereignty in effect asks Israel to become a binational state while creating a militarized Palestinian state alongside it. Bahour rejects the notion of unilateral action, but his case only reinforces my belief that Israel may need to act independently to protect its interests. The logic behind the Clinton parameters and President Obama’s peace plan was that in return for the creation of a Palestinian state, Palestinian refugees would relinquish their claim to Israel; the hope was that this would allow for the "two states for two peoples" to exist side-by-side. Yet Bahour rejects compromise on the refugee issue as the forfeiture of “basic components of statehood and basic principles of Israeli-Palestinian peace that are enshrined in international law.” Any peace agreement that both establishes a Palestinian state and recognizes the rights of millions of Palestinians to enter Israel would hasten the end of Israel's Jewish identity. Israel's interest in the creation of a Palestinian state is also built upon the assumption that a sound agreement would improve its security rather than threaten it. To this end, Israel has called for a demilitarized Palestinian state, and this has been echoed by the United States, France, the Czech Republic, the European Union, and Australia’s Labor Party. Even Mahmoud Abbas accepted the premise of demilitarization, saying, “We don’t need planes or missiles. All we need is a strong police force.” Nevertheless, Bahour’s piece declares any limitations on the sovereignty of Palestine unacceptable. For Israel, a peace deal that grants one’s adversaries access to more deadly weaponry would be absurd. Bahour argues that my strategies for reaching a two-state solution are doomed because they do not meet the "mutual interests" of the parties to the conflict, but his plan does not offer incentives for Israel to make peace. Bahour argues that my strategies for reaching a two-state solution are doomed because they do not meet the "mutual interests" of the parties to the conflict, but his plan does not offer incentives for Israel to make peace. His proposal not only fails to improve Israel's situation in any tangible sense, but further endangers it. Rejectionist Palestinian positions like Bahour's (and Abbas's recent dismissal of Biden's initiative) would veto the two-state solution as a means to move towards a single binational state. That is precisely why Israel may need to act independently to keep a two-state solution viable. Authors Amos Yadlin Full Article
independent Cabin Spacey offers 'pay-as-you-live, location-independent' prefab homes By www.treehugger.com Published On :: Thu, 20 Sep 2018 14:02:25 -0400 This company is working to build a network of urban prefabs under a 'pay-as-you-go' model of home ownership. Full Article Design
independent The Independent Looks at The Green Movement at Fifty By www.treehugger.com Published On :: Tue, 12 Jun 2012 09:25:00 -0400 The UK newspaper dates the movement back to the publishing of Rachel Carson's Silent Spring; I contribute with a guest post on architecture and design Full Article Design
independent This Black Friday, Occupy Main Street; Shop At A Local, Small Independent Merchant By www.treehugger.com Published On :: Tue, 22 Nov 2011 08:46:00 -0500 Lets declare a day of non-action, of unoccupying the big box stores. Instead, let's support our local, green neighborhood shops that need our custom. Full Article Business
independent Data From One of Europe's Largest Independent Liver Transplant Registries Reveals Improved Graft Survival Benefit in Patients Receiving Advagraf™ Prolonged Release Tacrolimus Compared to Those on Tacrolimus Immediate Release - Dr Aluvihare By feedproxy.google.com Published On :: 24 Feb 2015 10:36:00 EST Dr Aluvihare Full Article Biotechnology Healthcare Hospitals Medical Pharmaceuticals Clinical Trials Medical Discoveries MultiVu Video
independent Scandal Engulfs Independent Publisher ChiZine Publications By feedproxy.google.com Published On :: Fri, 15 Nov 2019 17:43:00 +0000 Posted by Victoria Strauss for Writer Beware®If you're not part of the horror or speculative fiction community, you may not be aware of the scandal that over the past two weeks has engulfed ChiZine Publications, a (previously) highly-regarded Canadian independent publisher.In September of last year, several authors, including Ed Kurtz, made a complaint to the Horror Writers Association about long-overdue royalties at ChiZine. On November 5 of this year, after the complaint became public knowledge, CZP posted a statement on its Facebook page, claiming that Kurtz's royalties were "currently paid in full" and that "Any other monies he might be due will be paid on his next royalty statement". Kurtz's response, posted by his partner on Facebook a day later, was blistering:The statement from Chizine neglects a number of salient facts, such as the moment in July 2018, at Necon, when I explained to Brett Savory that my partner was facing a layoff, our cat was ill, we were in severe financial distress, and I had *never* been paid a single cent of royalties in what was at that time almost two years for a moderately successful book. He actually grinned and said, "Things are hard for everyone right now" before walking away. The following morning it was reported to me that Sandra was loudly complaining in the dealer room about me having asked about my royalties, and of course the two of them went on a whirlwind trip around the world a few weeks after that, showing us all that things weren't so rough for them, after all.In fact, I'd asked after my royalties several times and was rebuffed or given excuses every single time (usually something wrong with their accounting software or something similar, which I later learned they’d been saying to authors for years). I only went to the HWA after several other frustrated CZP authors (one of whom hadn't been paid in five years!) strongly encouraged me to do so. I expressed fear of bullying and/or retaliation, and some of these authors promised me they'd have my back (they didn't). And yes, a lot of us got paid through my efforts, though it is untrue I'm paid in full. I was never paid royalties for the months of my first year of publication, 2016, though CZP continues to claim I was. I just gave up on this.Kurtz's experience was not isolated.******Between 2010 and 2015, Writer Beware received a handful of complaints (fewer than five) about ChiZine from authors who cited months-late royalty payments or long waits for contracts. Because the complaints were so few, and also because the authors all did eventually receive their payments or their contracts (though in most cases only after persistent prodding), it wasn't clear to me whether the tardiness indicated a pattern of problems, or was the kind of occasional glitch that can afflict otherwise reputable small presses with small staff and tight finances.As it turns out, those few complaints were just the tiniest bubbles drifting up from what appears to be a roiling ocean of dysfunction.Following Kurtz's public response, CZP authors and staff began to come forward with their own experiences--a tsunami of serious allegations including non-payment (some staff say they were never paid for years of work), extremely late or missing royalty payments (years in arrears in some cases; many authors report having to fight for what payment was received), erratically-produced royalty statements (CZP breached at least some of its own contracts by sending out royalties once a year instead of bi-annually--more on that below), missed pub dates, broken marketing promises, and financial mismanagement--especially concerning, since a big chunk of CZP's budget comes from grants and subsidies. (Former CZP staff member Michael Matheson has written a pair of illuminating posts on CZP's finances, including its treatment of grant money and habitual financial distress.)Staff and authors also--in multiple, strikingly similar posts and complaints, including some received by Writer Beware--cite a toxic work culture that featured bullying, intimidation, sexual harassment, racism, gaslighting, and more. Several of those who contacted me told me that they felt CZP operated "like a cult," with charismatic leaders at the top who were admired and feared in equal measure, and whom many dared not defy.This account only scratches the surface. For much more:Jason Sanford's Genre Grapevine column discusses the allegations against CZP, with quotes from authors he interviewed; and also looks at CZP's book sales, with data from Nielsen BookScan.Two posts from File770, plus one moreA roundup of coverage from High Fever BooksTonya "Tricia" Liburd's Twitter thread compiling statements and storiesOn November 11, CZP's founders, Sandra Kasturi and Brett Savory, posted a statement on the CZP blog and Facebook page indicating that they have decided to "step down." Although the statement mentions financial issues ("we have taken a short-term personal loan to bring payments up to date"), it doesn't address the many other complaints that have been leveled against the company--and, notably, does not include an apology.The response has not been kind.******Despite all of the above, there are still those who continue to defend CZP, and to brush off the statements by writers and staff. For example, this, from editor Stephen Jones (Jones's post has been removed; this is a screenshot posted to Twitter):What stands out for me here is not just the skepticism that whistleblowers always have to face (and which, even when the publisher doesn't try to intimidate or engage in reprisals, makes it so much harder for whistleblowers to come forward), but the defense of unprofessional business practice--not just by CZP but, apparently, by small press publishers in general. Small presses are doing something great for writers and readers, so we should "cut them some slack" when they fail to pay, or don't fill book orders, or miss a pub date, or engage in some other kind of behavior that has a negative impact on staff and authors. That's "simply the nature of small press publishing." Deal with it!It's a really common argument. I can't tell you how often I've seen some version of it--not just from toxic or troubled publishers, but from the writers they are screwing over. But it is bullshit. Complete and utter bullshit.No matter how "worthy" a publisher may be, that does not give it the right to abuse its writers or its staff--whether by accident or design. Publishers function in the realm of art, but they also need to function like businesses--not like cults of personality, not like sinecures, not like kitchen-table hobby projects where it doesn't really matter that they know little about publishing and have never run a business as long as they've got good intentions. You don't get a pass because you've got a noble goal. You don't get a pass because independent publishers are struggling and we need more of them. You don't even get a pass because you're putting out good books from disenfranchised authors. You need to run your business right, and treat your writers and your staff right, or you have no business calling yourself a publisher.Which brings me to my next point. The scope and range of what has apparently been happening at ChiZine is bigger than usual (and having seen as many small press implosions as I have over the years, it's amazing to me that it took so long for the scandal to break). But it's important to emphasize that it is not an isolated occurrence. Contract breaches, financial malfeasance, even the kind of harassment and gaslighting and dictatorial behavior that CZP authors and staff describe--all are rampant in the small press world. Just go back through a few years of the entries on this blog, and you'll see plenty of examples.I don't mean to tar all small presses with the same brush. There are, it's important to acknowledge, many small and indie publishers that operate with complete professionalism and do all they can to treat their authors right. But there is a huge, huge problem in the small press segment of the publishing industry, and we don't do writers--or readers--any favors in dismissing or downplaying or making excuses for it.I'm not the only one who is making this point. Silvia Moreno-Garcia, who had payment issues with CZP and also has experience running a micro-press, addresses the issue in a Twitter thread:In a blog post, former CZP staffer Michael Matheson responds to those who would like to see publishers like CZP dealt with more kindly: And, commenting on the Chizine situation, writer and reviewer Gabino Iglesias points out:I agree 100%. But I'm not holding my breath.******The scandal has unfolded very quickly but there've already been consequences. High Fever Books reports "a mass exodus" from CZP, with authors requesting rights reversions for their books, and withdrawing stories from CZP's forthcoming Christmas anthology. The Ontario Arts Council, one of CZP's funders, has recently removed CZP from its list of grant recommenders. And SFWA has issued a statement:******Finally, some semi-wonky publishing stuff.There's been some discussion of irregularities with CZP's royalty statements. I've seen a number of these, kindly shared with me by CZP authors, and while they're somewhat of a chore to figure out and are missing some information that ideally should be present, the numbers do add up. However, a few things are sub-optimal.- CZP's contract boilerplate empowers the publisher to set a "reasonable" reserve against returns. There are no specifics, so it's basically up to the publisher to decide what "reasonable" is.For CZP, "reasonable" seems to mean 50%. This seemed high to me, so I did a mini-canvass of literary agents on Twitter. Most agreed that smaller is better--maybe 25-30%, though some felt that 50% was justifiable depending on the circumstances. They also pointed out that the reserve percentage should fall in subsequent reporting periods (CZP's remains at 50%, unless boilerplate has been negotiated otherwise), and that publishers should not hold reserves beyond two or three years, or four or five accounting periods (CZP has held reserves for some authors for much longer).(If you're unclear on what a reserve against returns is, here's an explanation.)- Per CZP's contract, royalties are paid "by the first royalty period falling one year after publication." What this means in practice (based on the royalty statements I saw) is that if your pub date is (hypothetically) April of 2016, you are not eligible for payment until the first royalty period that follows your one-year anniversary--which, since CZP pays royalties just once a year on a January-December schedule, would be the royalty period ending December 2017. Since publishers often take months to issue royalty statements and payments following the end of a royalty period, you'd get no royalty check until sometime in 2018--close to, or possibly more than, two full years after publication.In effect, CZP is setting a 100% reserve against returns for at least a year following publication, and often much more. This gives it the use of the author's money for far too long, not to mention a financial cushion that lets it write smaller checks, since it doesn't have to pay anything out until after returns have come in (most sales and most returns occur during the first year of release).I shouldn't need to say that this is non-standard. It's also, in my opinion, seriously exploitative.- And...about that annual payment. It too is non-standard--even the big houses pay twice a year, and most small publishers pay quarterly or even more often. It's also extra-contractual--at least for the contracts I saw. According to CZP's boilerplate, payments are supposed to be bi-annual after that initial year-or-more embargo. The switch to annual payment appears to have been a unilateral decision by CZP owners for logistical and cost reasons, actual contract language be damned (I've seen documentation of this).- A final wonky contract point: CZP's contract boilerplate mentions royalty payments (as in, they're bi-annual)--but does not, anywhere, mention royalty statements.A publishing contract absolutely needs to bind a publisher not just to pay, but to account royalties on a regular basis (whether or not payments are due). If there's no contractual obligation for the publisher to provide royalty accounting, it may decline to do so--and that's not theoretical, I've gotten more than a few complaints about exactly this. Just one more reason to get knowledgeable advice on any publishing contract you're thinking of signing. Full Article
independent The Independent: Unless we empower women farmers, we may not have enough to feed the planet By www.iwmi.cgiar.org Published On :: Mon, 09 Mar 2020 02:30:07 +0000 In an opinion piece in The Independent, IWMI Director General Claudia Sadoff says "Achieving greater gender equality will help to strengthen the resilience of our food systems, revitalize rural economies and enhance rural livelihoods." Full Article IWMI in the news Z-Featured Content Z-News Claudia Sadoff Gender The Independant Woman Women
independent The Independent: Unless we empower women farmers, we may not have enough to feed the planet By feedproxy.google.com Published On :: Mon, 09 Mar 2020 02:30:07 +0000 In an opinion piece in The Independent, IWMI Director General Claudia Sadoff says "Achieving greater gender equality will help to strengthen the resilience of our food systems, revitalize rural economies and enhance rural livelihoods." Full Article IWMI in the news Z-Featured Content Z-News Claudia Sadoff Gender The Independant Woman Women
independent Georgia should strengthen civil service and independent judiciary to build on anti-corruption progress By www.oecd.org Published On :: Thu, 31 Oct 2013 16:43:00 GMT Georgia has achieved significant progress in reducing corruption over the past decade. To build on this progress, the Government should focus on strengthening its professional civil service and ensure independence of the judiciary, according to a new OECD report. Full Article
independent Designing effective independent fiscal institutions (IFIs) By www.oecd.org Published On :: Mon, 15 May 2017 15:22:00 GMT Independent fiscal institutions (IFIs) serve to promote sound fiscal policy and sustainable public finances. This report outlines good practices for their effective design and operation. Full Article
independent UK should consider border controls, say independent scientists By www.ft.com Published On :: Mon, 04 May 2020 17:55:37 GMT Britain failed to take advantage of island status, warns panel, as it calls for more transparency Full Article
independent Amber Heard wears a suit adorned with butterflies at the 2020 Film Independent Spirit Awards By www.dailymail.co.uk Published On :: Mon, 10 Feb 2020 09:15:02 GMT Amber Heard wore a Fendi butterfly suit to the Film Independent Spirit Awards. She was featured on recordings from her marriage to Johnny Depp as she admitted to hitting him. Full Article
independent The Voice: Nick Jonas blocks Kelly Clarkson from singer who covered her hit song Miss Independent By Published On :: Wed, 26 Feb 2020 08:20:28 +0000 The 27-year-old singer blocked Kelly Clarkson, 37, from pursuing a singer who covered her hit song Miss Independent on Tuesday's episode of The Voice. Full Article
independent Labour MPs call for Corbyn to set up independent investigation into anti-Semitism complaint handling By www.dailymail.co.uk Published On :: Mon, 15 Jul 2019 10:37:54 GMT The Tribune group of moderate Labour MPs said they were 'shocked' by claims made in a Panorama documentary 'about the handling of antisemitism complaints'. Full Article
independent Rachel Brosnahan has fun in a flirty pink skirt in a lipstick pattern at Independent Spirit Awards By Published On :: Sun, 09 Feb 2020 02:36:42 +0000 The House Of Cards actress, 29, topped off her look with a maroon leather crop top that showed off her shoulders, chest and bare midriff. Full Article
independent Jada Pinkett Smith admits Will Smith 'felt abandoned' when she tried to be more independent By www.dailymail.co.uk Published On :: Mon, 10 Jun 2019 22:48:09 GMT On a Red Table Talk episode posted Monday, Jada Pinkett Smith revealed to Esther Perel that Will Smith 'felt abandoned' when she wanted more independence in marriage. Full Article
independent Joe Alwyn looks sharp in a black suit as he goes solo for British Independent Film Awards By www.dailymail.co.uk Published On :: Mon, 02 Dec 2019 16:26:33 GMT The actor, 28, went solo as he attended the British Independent Film Awards 2019 in London on Sunday, after it was reported he would spend Thanksgiving weekend with girlfriend Taylor Swift. Full Article
independent Why independent restaurant owners are fighting third-party delivery platforms like Grubhub and Uber Eats By www.businessinsider.in Published On :: Wed, 15 Apr 2020 23:11:32 +0530 Mark Lennihan/AP ImagesThird-party delivery services are often seen by restaurant owners as a necessary evil.Third-party delivery platforms like Grubhub and Doordash claim to be helping restaurants through the pandemic, but restaurant owners say they're doing the opposite.Most delivery platforms charge restaurants a roughly 30% commission on every order, and restaurant owners say platforms have been slow to offer support and even pay what they owe.On Monday, Doordash announced it would slash fees by 50% through the end of May, but Grubhub is fighting a similar order in San Francisco.Business Insider spoke to restaurant data and marketing entrepreneur Abhinav Kapur, who said, "If there was ever a time to prove that you were a partner to the industry, now it would be the time to do it."Visit Full Article