Huai-Liang Chang and Mu-lin Li
Trans. Amer. Math. Soc. 373 (2020), 3669-3691.
Abstract, references and article information

Georg H H Borner
Apr 28, 2020; 0:R120.001971v1-mcp.R120.001971
Review

Protein subcellular localization is an essential and highly regulated determinant of protein function. Major advances in mass spectrometry and imaging have allowed the development of powerful spatial proteomics approaches for determining protein localization at the whole cell scale. Here, a brief overview of current methods is presented, followed by a detailed discussion of organellar mapping through proteomic profiling. This relatively simple yet flexible approach is rapidly gaining popularity, due to its ability to capture the localizations of thousands of proteins in a single experiment. It can be used to generate high-resolution cell maps, and as a tool for monitoring protein localization dynamics. This review highlights the strengths and limitations of the approach, and provides guidance to designing and interpreting profiling experiments. 

WASHINGTON — The Migration Policy Institute (MPI) today published the annual update to its data-rich article, Frequently Requested Statistics on Immigrants and Immigration in the United States, offering readers a wealth of information that can help inform understanding about an issue that is the subject of much conversation.

East India Company -- History.

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MundoFox estrenará “¿Quién Mató a Patricia Soler?” el lunes 9 de febrero a las 9PM/8c.