BACKGROUND:Practice on fasting prior to extubation in critically ill patients is variable. Efficacy of fasting in reducing gastric volume has not been well established. The primary objective of this study was to assess the effect of 4 h of fasting on prevalence of empty stomach using gastric ultrasonography in critically ill subjects who are fasted for extubation. The secondary objectives were to evaluate the change in gastric volumes during 4 h of fasting and to determine factors associated with empty stomach after fasting.METHODS:This was a single-center, prospective, observational study on adult ICU subjects who were enterally fed for at least 6 h continuously and mechanically ventilated. Gastric ultrasound was performed immediately prior to commencement of fasting, after 4 h of fasting, and after nasogastric (NG) aspiration after 4 h of fasting. An empty stomach was defined as a gastric volume ≤ 1.5 mL/kg.RESULTS:Forty subjects were recruited, and 38 (95%) had images suitable for analysis. The prevalence of empty stomach increased after 4 h of fasting (25 [65.8%] vs 31 [81.6%], P = .041) and after 4 h of fasting with NG aspiration (25 [65.8%] vs 34 [89.5%], P = .008). There was a significant difference in median (interquartile range) gastric volume per body weight between before fasting and 4 h after fasting (1.0 [0.5–1.8] mL/kg vs 0.4 [0.2–1.0] mL/kg, P < .001). No patient factors were associated with higher prevalence of empty stomach after 4 h of fasting.CONCLUSIONS:Most mechanically ventilated subjects had empty stomachs prior to fasting for extubation. Fasting for 4 h further increased the prevalence of empty stomach at extubation to > 80%.

BACKGROUND:The use of prone position (PP) has been widespread during the COVID-19 pandemic. Whereas it has demonstrated benefits, including improved oxygenation and lung aeration, the factors influencing the response in terms of gas exchange to PP remain unclear. In particular, the association between baseline quantitative computed tomography (CT) scan results and gas exchange response to PP in invasively ventilated subjects with COVID-19 ARDS is unknown. The present study aimed to compare baseline quantitative CT results between subjects responding to PP in terms of oxygenation or CO2 clearance and those who did not.METHODS:This was a single-center, retrospective observational study including critically ill, invasively ventilated subjects with COVID-19–related ARDS admitted to the ICUs of Niguarda Hospital between March 2020–November 2021. Blood gas samples were collected before and after PP. Subjects in whom the PaO2/FIO2 increase was ≥ 20 mm Hg after PP were defined as oxygen responders. CO2 responders were defined when the ventilatory ratio (VR) decreased during PP. Automated quantitative CT analyses were performed to obtain tissue mass and density of the lungs.RESULTS:One hundred twenty-five subjects were enrolled, of which 116 (93%) were O2 responders and 51 (41%) CO2 responders. No difference in quantitative CT characteristics and oxygen were observed between responders and non-responders (tissue mass 1,532 ± 396 g vs 1,654 ± 304 g, P = .28; density −544 ± 109 HU vs −562 ± 58 HU P = .42). Similar findings were observed when dividing the population according to CO2 response (tissue mass 1,551 ± 412 g vs 1,534 ± 377 g, P = .89; density −545 ± 123 HU vs −546 ± 94 HU, P = .99).CONCLUSIONS:Most subjects with COVID-19–related ARDS improved their oxygenation at the first pronation cycle. The study suggests that baseline quantitative CT scan data were not associated with the response to PP in oxygenation or CO2 in mechanically ventilated subjects with COVID-19–related ARDS.

For clean-room technologies such as isolators and restricted access barrier systems (RABS), decontamination using hydrogen peroxide (H₂O₂) is increasingly attractive to fulfill regulatory requirements. Several approaches are currently used, ranging from manual wipe disinfection to vapor phase hydrogen peroxide (VPHP) or automated nebulization sanitization. Although the residual airborne H₂O₂ concentration can be easily monitored, detection of trace H₂O₂ residues in filled products is rather challenging. To simulate the filling process in a specific clean room, technical runs with water for injection (WfI) are popular. Thus, the ability to detect traces of H₂O₂ in water is an important prerequisite to ensure a safe and reliable use of H₂O₂ for isolator or clean room decontamination. The objective of this study was to provide a validated quantitative, fluorometric Amplex UltraRed assay, which satisfies the analytical target profile of quantifying H₂O₂ in WfI at low nanomolar to low micromolar concentrations (ppb range) with high accuracy and high precision. The Amplex UltraRed technology provides a solid basis for this purpose; however, no commercial assay kit that fulfills these requirements is available. Therefore, a customized Amplex UltraRed assay was developed, optimized, and validated. This approach resulted in an assay that is capable of quantifying H₂O₂ in WfI selectively, sensitively, accurately, precisely, and robustly. This assay is used in process development and qualification approaches using WfI in H₂O₂-decontaminated clean rooms and isolators.

Background

Recently, cough reflex hypersensitivity has been proposed as a common underlying feature of chronic cough in adults. However, symptoms and clinical characteristics of cough hypersensitivity have not been studied amongst phenotypes of chronic cough. This study aimed to compare symptom features, such as cough triggers and associated throat sensations, of cough hypersensitivity in patients with asthmatic chronic cough and those with refractory chronic cough (RCC).

ABSTRACTDespite global consensus on the importance of male involvement in family planning, disparities persist in low- and middle-income countries, where women continue to bear the responsibility for these initiatives. The Philippines, with a high fertility rate and unmet family planning needs, exemplifies this challenge. We present the experiences and lessons learned from implementing the no-scalpel vasectomy (NSV) program in Davao City, showcasing its potential for increasing male engagement in family planning decisions. Launched in 2008, the program aimed to address gender disparity by promoting NSV as a safe and effective contraceptive alternative to female-centric methods. Through the use of culturally sensitive information campaigns and couple-focused counseling, the program challenged traditional notions of masculinity and encouraged shared decision-making. Strong local government commitment and public-private partnerships played key roles in driving the program’s success. Results showed an average annual increase of 80% in NSV clients over the past 3 years compared to before the COVID-19 pandemic, underscoring its effectiveness. The program presents a compelling intervention model for similar initiatives, highlighting how overcoming cultural barriers, infrastructure limitations, and budgetary constraints through policy advocacy, strategic partnerships, and tailored approaches can significantly boost male involvement in family planning and improve reproductive health outcomes within communities.

In Canada and across the globe, access to PSMA PET/CT is limited and expensive. For patients with biochemical recurrence (BCR) after treatment for prostate cancer, novel strategies are needed to better stratify patients who may or may not benefit from a PSMA PET scan. The role of the free-to-total prostate-specific antigen (PSA) ratio (FPSAR) in posttreatment prostate cancer, specifically in the PSMA PET/CT era, remains unknown. Our aim in this study was to determine the association of FPSAR in patients referred for ¹⁸F-DCFPyL PSMA PET/CT in the BCR setting and assess the correlation between FPSAR and ¹⁸F-DCFPyL PSMA PET/CT positivity (local recurrence or distant metastases). Methods: This prospective study included 137 patients who were referred for ¹⁸F-DCFPyL PSMA PET/CT and had BCR with a total PSA of less than 1 ng/mL after radical prostatectomy (RP) (including adjuvant or salvage radiotherapy). Blood samples were collected on the day of ¹⁸F-DCFPyL PSMA PET/CT. FPSAR was categorized as less than 0.10 or as 0.10 or more. A positive ¹⁸F-DCFPyL PSMA PET/CT scan was defined by a PROMISE classification lesion score of 2 or 3, irrespective of the site of increased tracer uptake (e.g., prostate, pelvic nodes, bone, or viscera). Results: Overall, 137 blood samples of patients with BCR after RP were analyzed to calculate FPSAR. The median age at ¹⁸F-DCFPyL PSMA PET/CT was 68.6 y (interquartile range, 63.0–72.4 y), and the median PSA at ¹⁸F-DCFPyL PSMA PET/CT was 0.3 ng/mL (interquartile range, 0.3–0.6 ng/mL). Eighty-six patients (62.8%) had an FPSAR of less than 0.10, whereas 51 patients (37.2%) had an FPSAR of 0.10 or more. An FPSAR of 0.10 or more was identified as an independent predictor of a positive ¹⁸F-DCFPyL PSMA PET/CT scan, with an odds ratio of 6.99 (95% CI, 2.96–16.51; P < 0.001). Conclusion: An FPSAR of 0.10 or more after RP independently correlated with increased odds of a positive ¹⁸F-DCFPyL PSMA PET/CT scan among BCR post-RP patients. These findings may offer an inexpensive method by which to triage access to ¹⁸F-DCFPyL PSMA PET/CT in jurisdictions where availability is not replete.

BACKGROUND AND PURPOSE:

Hemangioblastoma is a rare vascular tumor that occurs within the central nervous system in children. Differentiating hemangioblastoma from other posterior fossa tumors can be challenging on imaging, and preoperative diagnosis can change the neurosurgical approach. We hypothesize that a "lightbulb sign" on the arterial spin-labeling (ASL) sequence (diffuse homogeneous intense hyperperfusion within the solid component of the tumor) will provide additional imaging finding to differentiate hemangioblastoma from other posterior fossa tumors.

BACKGROUND AND PURPOSE:

Intracranial epidermoids temporal bone cholesteatomas, and head and neck epidermal inclusion cysts are typically slow-growing, benign conditions arising from ectodermal tissue. They exhibit increased signal on DWI. While much of the imaging literature describes these lesions as showing diffusion restriction, we investigated these qualitative signal intensities and interpretations of restricted diffusion with respect to normal brain structures. This study aimed to quantitatively evaluate the ADC values and histogram features of these lesions.

BACKGROUND AND PURPOSE:

Brain atrophy occurs in the late stage of dementia, yet structural MRI is widely used in the work-up. Atrophy patterns can suggest a diagnosis of Alzheimer disease (AD) or frontotemporal dementia (FTD) but are difficult to assess visually. We hypothesized that the availability of a quantitative volumetric brain MRI report would increase neuroradiologists’ accuracy in diagnosing AD, FTD, or healthy controls compared with visual assessment.

BACKGROUND AND PURPOSE:

Periprocedural intracranial hemorrhage is one of common complications after stent placement for symptomatic intracranial atherosclerotic stenosis. This study was conducted to demonstrate predictors and long-term outcomes of periprocedural intracranial hemorrhage after stent placement for symptomatic intracranial atherosclerotic stenosis.

BACKGROUND AND PURPOSE:

Mechanical thrombectomy is a fundamental intervention for acute ischemic stroke treatment. While conventional techniques are effective, cyclic aspiration (CyA) shows potential for better recanalization rates. We aim to investigate factors affecting CyA and compare them with static aspiration (StA).

T-lymphoblastic lymphoma (T-LLy) is the most common lymphoblastic lymphoma in children and often presents with a mediastinal mass. Lymphomatous suprarenal masses are possible but rare. Here, we discuss the case of a previously healthy 3-yr-old male who presented with mediastinal T-LLy with bilateral suprarenal masses. Following initial treatment, surgical biopsy of persisting adrenal masses revealed bilateral neuroblastoma (NBL). A clinical genetics panel for germline cancer predisposition did not identify any pathogenic variants. Combination large panel (864 genes) profiling analysis in the context of a precision oncology study revealed two novel likely pathogenic heterozygous variants: SMARCA4 c.1420-1G > T p.? and EZH2 c.1943G > C p.(Ile631Phefs*44). Somatic analysis revealed potential second hits/somatic variants in EZH2 (in the T-LLy) and a segmental loss in Chromosome 19p encompassing SMARCA4 (in the NBL). Synchronous cancers, especially at a young age, warrant genetic evaluation for cancer predisposition; enrollment in a precision oncology program assessing germline and tumor DNA can fulfill that purpose, particularly when standard first-line genetic testing is negative and in the setting of tumors that are not classic for common cancer predisposition syndromes.

Patient expectations of receiving antibiotics for common symptoms can trigger unnecessary use. We conducted a survey (n = 564) between January 2020 to June 2021 in public and private primary care clinics in Texas to study the prevalence and predictors of patients’ antibiotic expectations for common symptoms/illnesses. We surveyed Black patients (33%) and Hispanic/Latine patients (47%), and over 93% expected to receive an antibiotic for at least 1 of the 5 pre-defined symptoms/illnesses. Public clinic patients were nearly twice as likely to expect antibiotics for sore throat, diarrhea, and cold/flu than private clinic patients. Lack of knowledge of potential risks of antibiotic use was associated with increased antibiotic expectations for diarrhea (odds ratio [OR] = 1.6; 95% CI, 1.1-2.4) and cold/flu symptoms (OR = 2.9; 95% CI, 2.0-4.4). Lower education and inadequate health literacy were predictors of antibiotic expectations for diarrhea. Future antibiotic stewardship interventions should tailor patient education materials to include information on antibiotic risks and guidance on appropriate antibiotic indications.

Robert wants to be Tuxedo Mask, but with food and goggles. Kelley plays Find the Smell every day. Chris longs for freedom from his loot torture.

The post RPG Cast – Episode 707: “Pictomancers Working for Exposure” appeared first on RPGamer.

Paul Cousins presents a multi-channel installation in which the listener becomes the performer.

The post Patch Notes: Atomised Listening appeared first on Fact Magazine.

Following a tease, Microsoft and Activision Blizzard have announced Spyro Reignited Trilogy will release for Xbox Game Pass tomorrow, November 12.

VGChartz staff gave Spyro Reignited Trilogy an 8 out of 10 and stated, "it was wise to steer away from marketing the collection as a remaster because that label undercuts the developers’ level of dedication and investment in revitalizing these games."

Read details on the trilogy below:

Remade from the ground up, the Spyro Reignited Trilogy features all three of the original games that started it all – Spyro the Dragon, Spyro 2: Ripto’s Rage, and Spyro: Year of the Dragon, amazing for the original fans and new players alike.

Spyro the Dragon

Our new favorite little purple dragon starts on a quest to rescue his dragon friends who have been turned into crystal by the villain Gnasty Gnorc (what an unfortunate and yet apt name!). Spyro explores vibrant Dragon Realms, collects gems, and flambés his enemies, all while learning to how breathe fire and glide.

Spyro 2: Ripto’s Rage!

Spyro finds himself in the magical land of Avalar where he is trying to save the realm from the evil sorcerer Ripto and his minions. Along the way, he befriends new entirely new allies, overcomes challenges, complete tasks, and unlocks even more powers to take down Ripto and restore peace.

Spyro: Year of the Dragon

In Spyro: Year of the Dragon, Spyro finds out that the Dragon Eggs have been stolen by the devious Sorceress, sending him on a new mission to recover the eggs and save the dragon population. Our favorite purple dragon meets new friends, learns new abilities, all while exploring more vibrant realms with challenges (and treasures!).

Xbox players have been able to explore the Dragon Realms with Spyro since 2018 with the release of the Reignited Trilogy, and now we’re excited to invite our community to jump into these incredible adventures once again and relive the fun and nostalgia that only Spyro can bring.

Available on Game Pass Standard, Game Pass Ultimate, and PC Game Pass, for cloud, console and PC, it’s sure to ignite some serious fun. Let’s go save the Dragon Realms!

A life-long and avid gamer, William D'Angelo was first introduced to VGChartz in 2007. After years of supporting the site, he was brought on in 2010 as a junior analyst, working his way up to lead analyst in 2012 and taking over the hardware estimates in 2017. He has expanded his involvement in the gaming community by producing content on his own YouTube channel and Twitch channel. You can contact the author on Twitter @TrunksWD.

Full Article - https://www.vgchartz.com/article/463034/spyro-reignited-trilogy-headed-to-xbox-game-pass-tomorrow-november-12/

One of my favourite satires is the Screwtape Letters, an epistolary novel by Narnia scribe C.S. Lewis. It consists of messages from an oily elder demon to his nephew about how to correctly groom the soul of an unsuspecting human being. It's a claustrophobic send-up of managerial politics and nepotism, with World War 1 unfolding in the background. A real pick-me-up. Sintopia is the Two Point incarnation of that premise - in other words, brighter and breezier and definitely more slapstick than Christian. It puts you in charge of a world divided between Earth and hell, and challenges you to ensure a steady movement of optimally sinful souls between one and the other. Say your prayers and watch the trailer.

Read more

This is a sponsored article brought to you by Khalifa University of Science and Technology.

Abu Dhabi-based Khalifa University of Science and Technology in the United Arab Emirates (UAE) will be hosting the 36th edition of the IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS 2024) to highlight the Middle East and North Africa (MENA) region’s rapidly advancing capabilities in the robotics and intelligent transport systems.

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Themed “Robotics for Sustainable Development,” the IROS 2024 will be held from 14-18 October 2024 at the Abu Dhabi National Exhibition Center (ADNEC) in the UAE’s capital city. It will offer a platform for universities and research institutions to display their research and innovation activities and initiatives in robotics, gathering researchers, academics, leading corporate majors, and industry professionals from around the globe.

A total of 13 forums, nine global-level competitions and challenges covering various aspects of robotics and AI, an IROS Expo, as well as an exclusive Career Fair will also be part of IROS 2024. The challenges and competitions will focus on physical or athletic intelligence of robots, remote robot navigation, robot manipulation, underwater robotics, as well as perception and sensing.

Delegates for the event will represent sectors including manufacturing, healthcare, logistics, agriculture, defense, security, and mining sectors with 60 percent of the talent pool having over six years of experience in robotics. A major component of the conference will be the poster sessions, keynotes, panel discussions by researchers and scientists, and networking events.

Khalifa University will be hosting IROS 2024 to highlight the Middle East and North Africa (MENA) region’s rapidly advancing capabilities in the robotics and intelligent transport systems.Khalifa University

Abu Dhabi ranks first on the world’s safest cities list in 2024, according to online database Numbeo, out of 329 global cities in the 2024 standings, holding the title for eight consecutive years since 2017, reflecting the emirate’s ongoing efforts to ensure a good quality of life for citizens and residents.

With a multicultural community, Abu Dhabi is home to people from more than 200 nationalities and draws a large number of tourists to some of the top art galleries in the city such as Louvre Abu Dhabi and the Guggenheim Abu Dhabi, as well as other destinations such as Ferrari World Abu Dhabi and Warner Bros. World Abu Dhabi.

The UAE and Abu Dhabi have increasingly become a center for creative skillsets, human capital and advanced technologies, attracting several international and regional events such as the global COP28 UAE climate summit, in which more than 160 countries participated.

Abu Dhabi city itself has hosted a number of association conventions such as the 34th International Nursing Research Congress and is set to host the UNCTAD World Investment Forum, the 13th World Trade Organization (WTO) Ministerial Conference (MC13), the 12th World Environment Education Congress in 2024, and the IUCN World Conservation Congress in 2025.

Khalifa University’s Center for Robotics and Autonomous Systems (KU-CARS) includes a vibrant multidisciplinary environment for conducting robotics and autonomous vehicle-related research and innovation.Khalifa University

Dr. Jorge Dias, IROS 2024 General Chair, said: “Khalifa University is delighted to bring the Intelligent Robots and Systems 2024 to Abu Dhabi in the UAE and highlight the innovations in line with the theme Robotics for Sustainable Development. As the region’s rapidly advancing capabilities in robotics and intelligent transport systems gain momentum, this event serves as a platform to incubate ideas, exchange knowledge, foster collaboration, and showcase our research and innovation activities. By hosting IROS 2024, Khalifa University aims to reaffirm the UAE’s status as a global innovation hub and destination for all industry stakeholders to collaborate on cutting-edge research and explore opportunities for growth within the UAE’s innovation ecosystem.”

“This event serves as a platform to incubate ideas, exchange knowledge, foster collaboration, and showcase our research and innovation activities” —Dr. Jorge Dias, IROS 2024 General Chair

Dr. Dias added: “The organizing committee of IROS 2024 has received over 4000 submissions representing 60 countries, with China leading with 1,029 papers, followed by the U.S. (777), Germany (302), and Japan (253), as well as the U.K. and South Korea (173 each). The UAE with a total of 68 papers comes atop the Arab region.”

Driving innovation at Khalifa University is the Center for Robotics and Autonomous Systems (KU-CARS) with around 50 researchers and state-of-the-art laboratory facilities, including a vibrant multidisciplinary environment for conducting robotics and autonomous vehicle-related research and innovation.

IROS 2024 is sponsored by IEEE Robotics and Automation Society, Abu Dhabi Convention and Exhibition Bureau, the Robotics Society of Japan (RSJ), the Society of Instrument and Control Engineers (SICE), the New Technology Foundation, and the IEEE Industrial Electronics Society (IES).

More information at https://iros2024-abudhabi.org/

Marina Umaschi Bers has long been at the forefront of technological innovation for kids. In the 2010s, while teaching at Tufts University, in Massachusetts, she codeveloped the ScratchJr programming language and KIBO robotics kits, both intended for young children in STEM programs. Now head of the DevTech research group at Boston College, she continues to design learning technologies that promote computational thinking and cultivate a culture of engineering in kids.

What was the inspiration behind creating ScratchJr and the KIBO robot kits?

Marina Umaschi Bers: We want little kids—as they learn how to read and write, which are traditional literacies—to learn new literacies, such as how to code. To make that happen, we need to create child-friendly interfaces that are developmentally appropriate for their age, so they learn how to express themselves through computer programming.

How has the process of invention changed since you developed these technologies?

Bers: Now, with the maker culture, it’s a lot cheaper and easier to prototype things. And there’s more understanding that kids can be our partners as researchers and user-testers. They are not passive entities but active in expressing their needs and helping develop inventions that fit their goals.

What should people creating new technologies for kids keep in mind?

Bers: Not all kids are the same. You really need to look at the age of the kids. Try to understand developmentally where these children are in terms of their cognitive, social, emotional development. So when you’re designing, you’re designing not just for a user, but you’re designing for a whole human being.

The other thing is that in order to learn, children need to have fun. But they have fun by really being pushed to explore and create and make new things that are personally meaningful. So you need open-ended environments that allow children to explore and express themselves.

The KIBO kits teach kids robotics coding in a playful and screen-free way. KinderLab Robotics

How can coding and learning about robots bring out the inner inventors in kids?

Bers: I use the words “coding playground.” In a playground, children are inventing games all the time. They are inventing situations, they’re doing pretend play, they’re making things. So if we’re thinking of that as a metaphor when children are coding, it’s a platform for them to create, to make characters, to create stories, to make anything they want. In this idea of the coding playground, creativity is welcome—not just “follow what the teacher says” but let children invent their own projects.

What do you hope for in terms of the next generation of technologies for kids?

Bers: I hope we would see a lot more technologies that are outside. Right now, one of our projects is called Smart Playground [a project that will incorporate motors, sensors, and other devices into playgrounds to bolster computational thinking through play]. Children are able to use their bodies and run around and interact with others. It’s kind of getting away from the one-on-one relationship with the screen. Instead, technology is really going to augment the possibilities of people to interact with other people, and use their whole bodies, much of their brains, and their hands. These technologies will allow children to explore a little bit more of what it means to be human and what’s unique about us.

This article appears in the November 2024 print issue as “The Kids’ Inventor.”

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Quantum computing is a devilishly complex technology, with many technical hurdles impacting its development. Of these challenges two critical issues stand out: miniaturization and qubit quality.

IBM has adopted the superconducting qubit road map of reaching a 1,121-qubit processor by 2023, leading to the expectation that 1,000 qubits with today’s qubit form factor is feasible. However, current approaches will require very large chips (50 millimeters on a side, or larger) at the scale of small wafers, or the use of chiplets on multichip modules. While this approach will work, the aim is to attain a better path toward scalability.

Now researchers at MIT have been able to both reduce the size of the qubits and done so in a way that reduces the interference that occurs between neighboring qubits. The MIT researchers have increased the number of superconducting qubits that can be added onto a device by a factor of 100.

“We are addressing both qubit miniaturization and quality,” said William Oliver, the director for the Center for Quantum Engineering at MIT. “Unlike conventional transistor scaling, where only the number really matters, for qubits, large numbers are not sufficient, they must also be high-performance. Sacrificing performance for qubit number is not a useful trade in quantum computing. They must go hand in hand.”

The key to this big increase in qubit density and reduction of interference comes down to the use of two-dimensional materials, in particular the 2D insulator hexagonal boron nitride (hBN). The MIT researchers demonstrated that a few atomic monolayers of hBN can be stacked to form the insulator in the capacitors of a superconducting qubit.

Just like other capacitors, the capacitors in these superconducting circuits take the form of a sandwich in which an insulator material is sandwiched between two metal plates. The big difference for these capacitors is that the superconducting circuits can operate only at extremely low temperatures—less than 0.02 degrees above absolute zero (-273.15 °C).

Superconducting qubits are measured at temperatures as low as 20 millikelvin in a dilution refrigerator.Nathan Fiske/MIT

In that environment, insulating materials that are available for the job, such as PE-CVD silicon oxide or silicon nitride, have quite a few defects that are too lossy for quantum computing applications. To get around these material shortcomings, most superconducting circuits use what are called coplanar capacitors. In these capacitors, the plates are positioned laterally to one another, rather than on top of one another.

As a result, the intrinsic silicon substrate below the plates and to a smaller degree the vacuum above the plates serve as the capacitor dielectric. Intrinsic silicon is chemically pure and therefore has few defects, and the large size dilutes the electric field at the plate interfaces, all of which leads to a low-loss capacitor. The lateral size of each plate in this open-face design ends up being quite large (typically 100 by 100 micrometers) in order to achieve the required capacitance.

In an effort to move away from the large lateral configuration, the MIT researchers embarked on a search for an insulator that has very few defects and is compatible with superconducting capacitor plates.

“We chose to study hBN because it is the most widely used insulator in 2D material research due to its cleanliness and chemical inertness,” said colead author Joel Wang, a research scientist in the Engineering Quantum Systems group of the MIT Research Laboratory for Electronics.

On either side of the hBN, the MIT researchers used the 2D superconducting material, niobium diselenide. One of the trickiest aspects of fabricating the capacitors was working with the niobium diselenide, which oxidizes in seconds when exposed to air, according to Wang. This necessitates that the assembly of the capacitor occur in a glove box filled with argon gas.

While this would seemingly complicate the scaling up of the production of these capacitors, Wang doesn’t regard this as a limiting factor.

“What determines the quality factor of the capacitor are the two interfaces between the two materials,” said Wang. “Once the sandwich is made, the two interfaces are “sealed” and we don’t see any noticeable degradation over time when exposed to the atmosphere.”

This lack of degradation is because around 90 percent of the electric field is contained within the sandwich structure, so the oxidation of the outer surface of the niobium diselenide does not play a significant role anymore. This ultimately makes the capacitor footprint much smaller, and it accounts for the reduction in cross talk between the neighboring qubits.

“The main challenge for scaling up the fabrication will be the wafer-scale growth of hBN and 2D superconductors like [niobium diselenide], and how one can do wafer-scale stacking of these films,” added Wang.

Wang believes that this research has shown 2D hBN to be a good insulator candidate for superconducting qubits. He says that the groundwork the MIT team has done will serve as a road map for using other hybrid 2D materials to build superconducting circuits.

“Cover, bring to a boil, then reduce heat. Simmer for 20 minutes.” These directions seem simple enough, and yet I have messed up many, many pots of rice over the years. My sympathies to anyone who’s ever had to boil rice on a stovetop, cook it in a clay pot over a kerosene or charcoal burner, or prepare it in a cast-iron cauldron. All hail the 1955 invention of the automatic rice cooker!

How the automatic rice cooker was invented

It isn’t often that housewives get credit in the annals of invention, but in the story of the automatic rice cooker, a woman takes center stage. That happened only after the first attempts at electrifying rice cooking, starting in the 1920s, turned out to be utter failures. Matsushita, Mitsubishi, and Sony all experimented with variations of placing electric heating coils inside wooden tubs or aluminum pots, but none of these cookers automatically switched off when the rice was done. The human cook—almost always a wife or daughter—still had to pay attention to avoid burning the rice. These electric rice cookers didn’t save any real time or effort, and they sold poorly.

But Shogo Yamada, the energetic development manager of the electric appliance division for Toshiba, became convinced that his company could do better. In post–World War II Japan, he was demonstrating and selling electric washing machines all over the country. When he took a break from his sales pitch and actually talked to women about their daily household labors, he discovered that cooking rice—not laundry—was their most challenging chore. Rice was a mainstay of the Japanese diet, and women had to prepare it up to three times a day. It took hours of work, starting with getting up by 5:00 am to fan the flames of a kamado, a traditional earthenware stove fueled by charcoal or wood on which the rice pot was heated. The inability to properly mind the flame could earn a woman the label of “failed housewife.”

In 1951, Yamada became the cheerleader of the rice cooker within Toshiba, which was understandably skittish given the past failures of other companies. To develop the product, he turned to Yoshitada Minami, the manager of a small family factory that produced electric water heaters for Toshiba. The water-heater business wasn’t great, and the factory was on the brink of bankruptcy.

How Sources Influence the Telling of History

As someone who does a lot of research online, I often come across websites that tell very interesting histories, but without any citations. It takes only a little bit of digging before I find entire passages copied and pasted from one site to another, and so I spend a tremendous amount of time trying to track down the original source. Accounts of popular consumer products, such as the rice cooker, are particularly prone to this problem. That’s not to say that popular accounts are necessarily wrong; plus they are often much more engaging than boring academic pieces. This is just me offering a note of caution because every story offers a different perspective depending on its sources.

For example, many popular blogs sing the praises of Fumiko Minami and her tireless contributions to the development of the rice maker. But in my research, I found no mention of Minami before Helen Macnaughtan’s 2012 book chapter, “Building up Steam as Consumers: Women, Rice Cookers and the Consumption of Everyday Household Goods in Japan,” which itself was based on episode 42 of the Project X: Challengers documentary series that was produced by NHK and aired in 2002.

If instead I had relied solely on the description of the rice cooker’s early development provided by the Toshiba Science Museum (here’s an archived page from 2007), this month’s column would have offered a detailed technical description of how uncooked rice has a crystalline structure, but as it cooks, it becomes a gelatinized starch. The museum’s website notes that few engineers had ever considered the nature of cooking rice before the rice-cooker project, and it refers simply to the “project team” that discovered the process. There’s no mention of Fumiko.

Both stories are factually correct, but they emphasize different details. Sometimes it’s worth asking who is part of the “project team” because the answer might surprise you. —A.M.

Although Minami understood the basic technical principles for an electric rice cooker, he didn’t know or appreciate the finer details of preparing perfect rice. And so Minami turned to his wife, Fumiko.

Fumiko, the mother of six children, spent five years researching and testing to document the ideal recipe. She continued to make rice three times a day, carefully measuring water-to-rice ratios, noting temperatures and timings, and prototyping rice-cooker designs. Conventional wisdom was that the heat source needed to be adjusted continuously to guarantee fluffy rice, but Fumiko found that heating the water and rice to a boil and then cooking for exactly 20 minutes produced consistently good results.

But how would an automatic rice cooker know when the 20 minutes was up? A suggestion came from Toshiba engineers. A working model based on a double boiler (a pot within a pot for indirect heating) used evaporation to mark time. While the rice cooked in the inset pot, a bimetallic switch measured the temperature in the external pot. Boiling water would hold at a constant 100 °C, but once it had evaporated, the temperature would soar. When the internal temperature of the double boiler surpassed 100 °C, the switch would bend and cut the circuit. One cup of boiling water in the external pot took 20 minutes to evaporate. The same basic principle is still used in modern cookers.

Yamada wanted to ensure that the rice cooker worked in all climates, so Fumiko tested various prototypes in extreme conditions: on her rooftop in cold winters and scorching summers and near steamy bathrooms to mimic high humidity. When Fumiko became ill from testing outside, her children pitched in to help. None of the aluminum and glass prototypes, it turned out, could maintain their internal temperature in cold weather. The final design drew inspiration from the Hokkaidō region, Japan’s northernmost prefecture. Yamada had seen insulated cooking pots there, so the Minami family tried covering the rice cooker with a triple-layered iron exterior. It worked.

How Toshiba sold its automatic rice cooker

Toshiba’s automatic rice cooker went on sale on 10 December 1955, but initially, sales were slow. It didn’t help that the rice cooker was priced at 3,200 yen, about a third of the average Japanese monthly salary. It took some salesmanship to convince women they needed the new appliance. This was Yamada’s time to shine. He demonstrated using the rice cooker to prepare takikomi gohan, a rice dish seasoned with dashi, soy sauce, and a selection of meats and vegetables. When the dish was cooked in a traditional kamado, the soy sauce often burned, making the rather simple dish difficult to master. Women who saw Yamada’s demo were impressed with the ease offered by the rice cooker.

Another clever sales technique was to get electricity companies to serve as Toshiba distributors. At the time, Japan was facing a national power surplus stemming from the widespread replacement of carbon-filament lightbulbs with more efficient tungsten ones. The energy savings were so remarkable that operations at half of the country’s power plants had to be curtailed. But with utilities distributing Toshiba rice cookers, increased demand for electricity was baked in.

Within a year, Toshiba was selling more than 200,000 rice cookers a month. Many of them came from the Minamis’ factory, which was rescued from near-bankruptcy in the process.

How the automatic rice cooker conquered the world

From there, the story becomes an international one with complex localization issues. Japanese sushi rice is not the same as Thai sticky rice which is not the same as Persian tahdig, Indian basmati, Italian risotto, or Spanish paella. You see where I’m going with this. Every culture that has a unique rice dish almost always uses its own regional rice with its own preparation preferences. And so countries wanted their own type of automatic electric rice cooker (although some rejected automation in favor of traditional cooking methods).

Yoshiko Nakano, a professor at the University of Hong Kong, wrote a book in 2009 about the localized/globalized nature of rice cookers. Where There Are Asians, There Are Rice Cookers traces the popularization of the rice cooker from Japan to China and then the world by way of Hong Kong. One of the key differences between the Japanese and Chinese rice cooker is that the latter has a glass lid, which Chinese cooks demanded so they could see when to add sausage. More innovation and diversification followed. Modern rice cookers have settings to give Iranians crispy rice at the bottom of the pot, one to let Thai customers cook noodles, one for perfect rice porridge, and one for steel-cut oats.

My friend Hyungsub Choi, in his 2022 article “Before Localization: The Story of the Electric Rice Cooker in South Korea,” pushes back a bit on Nakano’s argument that countries were insistent on tailoring cookers to their tastes. From 1965, when the first domestic rice cooker appeared in South Korea, to the early 1990s, Korean manufacturers engaged in “conscious copying,” Choi argues. That is, they didn’t bother with either innovation or adaptation. As a result, most Koreans had to put up with inferior domestic models. Even after the Korean government made it a national goal to build a better rice cooker, manufacturers failed to deliver one, perhaps because none of the engineers involved knew how to cook rice. It’s a good reminder that the history of technology is not always the story of innovation and progress.

Eventually, the Asian diaspora brought the rice cooker to all parts of the globe, including South Carolina, where I now live and which coincidentally has a long history of rice cultivation. I bought my first rice cooker on a whim, but not for its rice-cooking ability. I was intrigued by the yogurt-making function. Similar to rice, yogurt requires a constant temperature over a specific length of time. Although successful, my yogurt experiment was fleeting—store-bought was just too convenient. But the rice cooking blew my mind. Perfect rice. Every. Single. Time. I am never going back to overflowing pots of starchy water.

Part of a continuing series looking at historical artifacts that embrace the boundless potential of technology.

An abridged version of this article appears in the November 2024 print issue as “The Automatic Rice Cooker’s Unlikely Inventor.”

References

Helen Macnaughtan’s 2012 book chapter, “Building up Steam as Consumers: Women, Rice Cookers and the Consumption of Everyday Household Goods in Japan,” was a great resource in understanding the development of the Toshiba ER-4. The chapter appeared in The Historical Consumer: Consumption and Everyday Life in Japan, 1850-2000, edited by Penelope Francks and Janet Hunter (Palgrave Macmillan).

Yoshiko Nakano’s book Where There are Asians, There are Rice Cookers (Hong Kong University Press, 2009) takes the story much further with her focus on the National (Panasonic) rice cooker and its adaptation and adoption around the world.

The Toshiba Science Museum, in Kawasaki, Japan, where we sourced our main image of the original ER-4, closed to the public in June. I do not know what the future holds for its collections, but luckily some of its Web pages have been archived to continue to help researchers like me.

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