The invention is directed to a single-step method for rapidly and efficiently preparing protein-polymer conjugates, including an insulin-polymer conjugate. According to the method of the present invention, a protein and hydrophilic polymer are contacted in the presence of at least one organic solvent and at least one metal chelator, under conditions that promote the formation of a conjugate of the protein and polymer. Thus, the invention is directed to the site-specific modification of selected proteins, such as insulin, with poly(ethylene glycol) at residue PheB1. The invention also provides a pharmaceutical formulation for encapsulating the conjugate in a biodegradable polymer.

Disclosed is a method of producing an organic light emitting device, an organic light emitting device produced by using the method, and an apparatus used in the method. The method includes preparing a first electrode, forming one or more organic material layers on the first electrode, and forming a second electrode on the organic material layers, wherein the method includes changing functions of predetermined pattern regions of one or more layers of the organic material layers or the electrodes.

An electron emission source includes nano-sized acicular materials and a cracked portion formed in at least one portion of the electron emission source. The acicular materials are exposed between inner walls of the cracked portion. A method for preparing the electron emission source, a field emission device including the electron emission source, and a composition for forming the electron emission source are also provided in the present invention.

Process for preparing hydrocyanic acid by catalytic dehydration of gaseous formamide, wherein the dehydration of formamide is coupled with an exothermic reaction by the reactor used in the dehydration comprising two separate fluid paths which are separated by a common reactor wall, with one fluid path being provided for the dehydration of formamide and the second fluid path being provided for the exothermic reaction.

A method of preparing functionalized graphene, comprises treating graphene with an alkali metal in the presence of an electron transfer agent and coordinating solvent, and adding a functionalizing compound. The method further includes quenching unreacted alkali metal by addition of a protic medium, and isolating the functionalized graphene.

Described is a process for preparing platinum-carbene complexes.

The present invention relates to a polyurethane ballast layer, the method for preparing the same and a railway comprising the polyurethane ballast layer. The polyurethane ballast layer provided in this invention comprises a polyurethane-filled ballast layer and a polyurethane external protective layer, wherein the polyurethane-filled ballast layer comprises ballasts and polyurethane foam filled in the space among the ballasts. The polyurethane ballast layer provided in this invention can reduce the probability of ballast crashing, shifting and cracking under heavy load, and separate the ballast track from the outside environment to prevent rain, snow and wastes from entering into the internal space of the ballast track bed. Furthermore, the polyurethane ballast layer can keep the polyurethane foam filled in the ballasts layer away from water in the outside environment to avoid hydrolysis. The polyurethane ballast layer presented in this invention can be used in the railway ballast track bed to extend the track bed maintenance cycle, and save maintenance cost significantly.

An implement is disclosed for smoothing grounds that include at least a compact base having a top surface and a lesser compact footing on top of the base. The implement includes a frame having a front portion, a central portion, a rear portion, and a width. Wheels are mounted for rotation directly to the frame, and tools are carried by the frame for engagement with the ground. The tools include a specially shaped cleaving blade connected to the rear portion of the frame by a tool support, which securely connects the cleaving blade at predetermined heights. The blade has a front shaving edge and a rear compressing edge. The blade extends straight across the width of the frame so as to maximize the drag displaced on the frame during use of the blade. Arrangement of the wheels directly on the frame provides optimal stabilization of the frame during operation of the blade.

A system for preparing a coffee beverage, provided with a coffee making apparatus comprising a grinder for grinding coffee beans to obtain ground coffee, a coffee beverage preparation device arranged for, with supply of water to the ground coffee, preparing the coffee beverage, and a coffee outlet for dispensing the coffee beverage, a separate coffee bean package with an inner space which at least before use is filled with the coffee beans, wherein the coffee bean package before use is closed off in itself such that the exposure of the coffee beans to ambient air is prevented, a coffee bean inlet for supply of coffee beans from the coffee bean package to the grinder, and a connecting device for connecting the coffee bean package to the coffee making apparatus.

The invention relates to a process for the milling-drying of a raw mixture containing aluminum trihydroxide having an average particle size D50 in the range from 50 to 130 μm and a specific BET surface area in the range from 0.01 to 0.5 m2/g and containing from 0.1 to 20% by weight of water, based on the raw mixture, which including the steps i) introduction of the raw mixture into a milling-drying apparatus,ii) introduction of a hot air stream having a temperature in the range from 20 to 100° C. into the milling-drying apparatus so as to flow through the milling-drying apparatus andiii) comminution of the aluminum trihydroxide present in the raw mixture in the milling-drying apparatus.

Solutions formed by combining poly(α(1→3) glucan) with CS2 in aqueous alkali metal hydroxide solution have been shown to produce the xanthated form of the poly(+(1→3) glucan). The solutions so formed have been shown to be useful for solution spinning into fiber of poly(α(1→3) glucan) when the spun fiber is coagulated in an acidic coagulation bath. The fibers so produced exhibit desirable physical properties. The poly(α(1→3) glucan) employed was synthesized by fermentation.

Method, apparatus, and system for preparing a cellular material based on hollow metal beads. According to the description, at least one bead chain in which said hollow metal beads are linked to one another in pairs by means of an articulation is used as elementary structure constituting the cellular material.

A system for preparing a pre-assembled hanger support. The system includes a bending tool operable to form a bight in the distal end of a structural wire, the bight having a transverse tail extending away from the shaft of the structural wire. The system also includes a wrapping tool having a drive rotor with a clip attachment interface that removably supports a hanger clip and provides selective rotation of the hanger clip and the structural wire, a wire support brace that supports the shaft of the structural wire in substantial alignment with the axis of rotation of the drive rotor, and a tail stop positioned to restrain the rotation of the transverse tail. The hanger clip is supported about the structural wire and positioned within the bight, and together the hanger clip and structural wire are installed onto the clip attachment interface, so that selective rotation of the drive rotor rotates the hanger clip and shaft of the structural wire causing the restrained transverse tail to wrap around the shaft and secure the hanger clip within an eyelet formed in the structural wire, thereby forming the pre-assembled hanger support.

A novel crystalline hybrid solid with a mixed organic-inorganic matrix is described which has a three-dimensional structure containing an inorganic framework with metallic centers based on zinc connected together via deprotonated organic ligands constituted by the entity —O2C—C6H2—(O)2—CO2. This novel solid is termed IM-21 and has an X-ray diffraction diagram as given below.

A process for preparing a seam area for a paper machine clothing (PMC) base fabric includes the steps of: forming the PMC base fabric by flat-weaving, the PMC base fabric including warp yarns extending in machine direction and weft yarns extending in cross machine direction and interwoven with the warp yarns, the weft yarns including first weft yarns and a second weft yarn, the second weft yarn being a multifilament yarn, the warp yarns, the first weft yarns, and the multifilament yarn being woven together on a loom in an original weaving process, the multifilament yarn being positioned in an anticipated seam area; and folding over the PMC base fabric, after weaving the multifilament yarn with the warp yarns, to form a seam loop of the PMC base fabric such that the multifilament yarn is a first one of the weft yarns on a sheet side of the seam loop.

An apparatus is configured to receive a tire having at least two bead portions, including a first bead portion and a second bead portion. The apparatus includes a plurality of members configured to engage the first bead portion of the tire, at least one expander configured to move the plurality of members outward, and a rotating device configured to rotate the plurality of members about an axis of the tire.

Processes comprising: melting a mixture comprising a valve metal precursor and a diluting agent in at least one first vessel under a first set of temperature and residence time conditions; transferring the mixture to at least one second vessel; and initiating, in the at least one second vessel, a reaction of the valve metal precursor to form a valve metal under a second set of temperature and residence time conditions; valve metal powder prepared thereby and uses therefor.

An apparatus for preparing infant formula to be supplied to a bottle, and methods and circuits for operating the same, are disclosed. The apparatus includes a housing having a shape for integrating together components of the apparatus. A fluid reservoir for holding fluid and configured to be coupling to the housing is provided. Further provided is a formula disc disposed at a first location of the housing. The first location defined above a dispense location of the bottle, and the formula disc having a top end and a dispense end, the formula disc further includes a plurality of slots for holding the infant formula in a powder state. The apparatus has an end plate that is coupled to the dispense end of the formula disc, and the end plate has a dispense hole, such that the end plate is rotatable relative to the formula disc.

A system for preparing a beverage suitable for consumption, for instance coffee and/or tea, is disclosed. The system comprises an apparatus for dispensing beverage under pressure to a nozzle of the system, and at least one receiving chamber which is placeable or is placed downstream of this nozzle. During use, the nozzle spouts a jet of the beverage with relatively high velocity to and/or into the receiving chamber. The receiving chamber is provided with at least one outflow opening for dispensing beverage received in this chamber. The system is at least configured to substantially counteract or prevent formation of foam of this beverage, in particular when the beverage is spouted to and/or into the receiving chamber. Further disclosed is an assembly at least provided with a holder, to a holder, a receiving body, the use of a said system and to a method for preparing a beverage suitable for consumption.

The invention provides a new method for preparing ultra-small polymeric-lipidic delivery nanoparticles (USDNs) that were synthesized by a nanoprecipitation method followed by a layer-by-layer nanodeposition. The USDNs particle size can be controlled between 5-25 mn and provides loading capacities of 22.12% to 72.08%. Moreover, the USDNs platform provides pH controlled drug release, within a terminal release ratio of 68% at pH 5.0 and almost no release to pH of 7.5. Furthermore, based on their small sizes (5-25 nm) and unique composition, the USDNs penetrates the skin strata efficiently, release the payload at the target site as topical or transdermal treatment of a variety of skin disorders. Additionally the USDNs system can be used to treat and diagnoses other crucial diseases (Cancer, Alzheimer, etc) can be combined with various micro-needles or needles free array technologies for special application.

The invention relates to a capsule for the preparation of a beverage in a beverage preparation device. The capsule has a flange which is partially made of paper and partially made of polymer. The polymer is essentially arranged on the flange to cover at least partially the paper part and so to improve the inside tightness of the capsule, in particular, to prevent air enters inside the capsule via folds and creases.

Pancake mixes comprising at least one type of whole grain flour, at least one natural sweetener, at least one fat and a leavening system are provided herein. Packaged food products comprising single-serving containers containing said pancake mixes, as well as methods of preparing pancakes, are also provided. The pancakes described herein are preferably 100% whole grain and free from preservatives and/or artificial colorings.

A brewing system includes a brewing apparatus and a capsule containing a substance for brewing. The capsule has an opening on one side and a base on an opposite side. The base includes a light input surface, a light-output surface and a light conductor to conduct light from the light input surface to the light output surface. The apparatus includes: a brewing chamber including an inlet for heated water, an outlet for the brewed beverage, and an opening in communication with the opening of the capsule. A light source on the brewing apparatus emits light into the base via the light inlet surface of the capsule. The light conductor conducts the light to the light-output surface. A light detector of the brewing apparatus detects light emitted by light-output surface on the base of the capsule. A method of operating the brewing system and a capsule system are also described.

A cartridge (10) containing a dose (12) of at least one substance for preparing a liquid product, e.g., coffee, by means of liquid and/or steam introduced into the cartridge (10). The cartridge comprises a body (14) containing the aforesaid dose (12), with a bottom wall (142), through which the liquid product is able to flow out of the cartridge (10), and a cover (16) that closes the body of the cartridge (10) at the end of the body opposite to the bottom wall (142). The body (14) comprises a crushed-plant-fibre material (e.g., with a base of rice husk), which may also be used for producing the cover. Alternatively, the cover (16) may be made of paper material (e.g., filter paper). The body (14) and the cover (16) are connected together via purely mechanical connection, it thus being possible to avoid gluing or welding.

A capsule for preparing a predetermined quantity of beverage suitable for consumption using an extractable product is disclosed. The capsule includes a circumferential first wall, a second wall closing the circumferential first wall at a first end, and a flexible sheet-shaped third wall closing the circumferential first wall at a second, open, end opposite the second wall, the third wall being at least one of perforate and porous. The first, second and third wall enclose an inner space including the extractable product. The third wall forms an outermost boundary of the capsule in an axial direction thereof. The third wall includes a filtering material. The second wall is one of a flexible porous sheet, a flexible foil provided with a plurality of entrance openings, and a substantially rigid wall that comprises a plurality of entrance openings.

A method for preparing a boron fertilizer, including: (1) heating boric acid to a temperature of 180-200° C., maintaining the temperature for 20-30 min for dehydration of the boric acid to yield pyroboric acid; and (2) cooling down the pyroboric acid to a temperature of 40-60° C., crushing, and screening to yield a powdered, weakly acidic, high-content boron fertilizer. The method is energy-saving, environmentally friendly, and low in cost. The resulting boron fertilizer is weakly acidic, fast in dissolution rate, and has excellent in compounding performance

An esteramide compound of the following formula (I): R1OOC-A-CONR2R3 (I) is described, wherein: A is a covalent bond or a methylene group —CH2—;R1 is an optionally substituted, saturated or unsaturated aliphatic or cycloaliphatic hydrocarbon group including from 5 to 36 carbon atoms,R2 and R3, either identical or different, are groups selected from a hydrogen atom, and optionally substituted hydrocarbon groups, preferably including from 1 to 36 carbon atoms, andR2 and R3 not being simultaneously hydrogen atoms. Also described, are applications for using the esteramide compound, notably as a solvent.

The invention is directed to a method for preparing a pyrotechnic composition, to the use of a water-soluble cellulose ether binder, to a pyrotechnic composition, to a method for preparing a pyrotechnic charge, and to a pyrotechnic charge. The method of the invention comprises mixing the fibrous nitrocellulose in wet form with the one or more water-soluble cellulose ether binders and optionally one or more solvents, wherein the amount of organic solvent in the mixture is 10 wt. % or less based on total weight of the mixture.

There are described powders comprising agglomerated nanocrystals of an electroactive alloy and oxygen. The main component of the alloy can be of nickel, cobalt, iron or mixtures thereof while the alloying element is one or more transition metals such as Mo, W, V, the alloy also including oxygen. Preferably the nanocrystals will be made of an alloy of nickel, molybdenum and oxygen. An electrode which is used by compacting the powders is also disclosed. Also disclosed, is a process for producing the powders by providing particles of nickel, cobalt and iron or oxides thereof with particles of at least one transition metal, (Mo, W, V) or oxides thereof and subjecting the particles to high energy mechanical alloying such as ball milling under conditions which include oxygen and for a sufficient period of time to produce a nanocrystalline alloy. Electrodes produced from these powders have an electrocatalytic activity for the hydrogen evolution which is comparable or higher than the electrodes which are presently used in the electrochemical industry. Moreover, these materials present an excellent chemical, electrochemical and mechanical stability. When use as a cathode the powders are useful in water electrolyzers, in chlor-alkali or the like cells.

The present invention relates to a positive electrode active material for a sodium secondary battery, and a method for preparing the same. The positive electrode active material for the sodium secondary battery according to the present invention is structurally more stable by replacing a part of the transition metal with Li, and accordingly, the thermal stability and life characteristics of the sodium battery including the positive electrode active material are greatly improved.

Disclosed are a reversible fuel cell oxygen electrode in which IrO2 is electrodeposited and formed on a porous carbon material and platinum is applied thereon to form a porous platinum layer, a reversible fuel cell including the same, and a method for preparing the same. According to the corresponding reversible fuel cell oxygen electrode, as the loading amounts of IrO2 and platinum used in the reversible fuel cell oxygen electrode can be lowered, it is possible to exhibit excellent reversible fuel cell performances (excellent fuel cell performance and water electrolysis performance) by improving the mass transport of water and oxygen while being capable of reducing the loading amounts of IrO2 and platinum. Further, it is possible to exhibit a good activity of a catalyst when the present disclosure is applied to a reversible fuel cell oxygen electrode and to reduce corrosion of carbon.

Disclosed is an anode for a molten carbonate fuel cell (MCFC) having improved creep property by adding an additive for imparting creep resistance to nickel-aluminum alloy and nickel as materials for an anode. Improved sintering property, creep property and increased mechanical strength of a molten carbonate fuel cell may be obtained accordingly.

The device has a line arrangement (2), which possesses an inlet (3) connectable to a supply line and an outlet (4) connectable to a shower arm (5). A heating element (6) serves for the provision of warm water. An energy store (7, 8) is provided, with which the power range for the provision of shower water can be extended. The heating element (6) for the provision of warm water is, in particular, a continuous-flow heater. The energy store (7, 8) is, in particular, a thermal, electrical, electrochemical or chemical energy store. During the shower process, the energy store is available as an additional energy source for the preparation of shower water.

Method for producing a uranium concentrate in the form of solid particles, by precipitation from a uranium-containing solution using a precipitating agent, in a vertical reactor comprising a base, a top, a central part, an upper part, and a lower part, the solid particles of the uranium concentrate forming a fluidized bed under the action of a rising liquid current which circulates from the base towards the top of the reactor successively passing through the lower part, the central part and the upper part of the reactor, and which is created by introducing a liquid recycling current (flow) at the base of the reactor, said liquid recycling current being tapped at a first determined level (A) in the upper part of the reactor and sent back without settling to the base of the reactor, excess liquid being also evacuated via an overflow located at a second determined level (B) in the upper part of the reactor; a method in which the upper limit (C) of the fluidized bed of solid particles is controlled so that it is positioned at a level below the first and second determined levels.

A method for preparing an object to be tested, having a given relative permittivity, intended to be illuminated by an incident electromagnetic wave. The method includes: providing a part including a cavity for housing the object and at least one extension element made from a material having a relative permittivity that is preferably equal to that of the object, the extension element at least partially delimiting the cavity and extending to either side of the cavity in a passage direction of the cavity, over a length at least equal, on either side of the cavity, to one third of the length of the cavity in the passage direction, and placing the object in the cavity, such that the object is in contact with the extension element in the passage direction.

A device for preparing bio-oil, a system for preparing bio-oil and a method for preparing bio-oil using the same are provided. Biomass is supplied to an inclined portion of a reactor, and high-temperature hot sand is supplied to an upper side of the biomass supplied to the inclined portion. Then, a heater heats the inclined portion. Thus, the fast pyrolysis performance of the biomass can be enhanced, thereby increasing the yield of bio-oil. Also, combustion gas produced from the heater is supplied to the interior of the reactor, so that the interior of the reactor can be simply formed under a nonoxidizing atmosphere. Accordingly, the device for preparing bio-oil can be manufactured into a very simple structure.

Oscar “Paris” Jackson Jr. is a rapper, songwriter, and producer who has been a militant voice for justice in the rap world since the 1980s. He came out of the Bay Area’s small but diverse and creative hip-hop scene towards the end of that decade, and made a splash with his 1990 debut album The Devil Made Me Do It, which mixed innovative musical choices with Black Panther-inspired politics and a Nation of Islam-influenced spiritual bent.

But it was his second album, 1992’s Sleeping With the Enemy, that really brought Paris to the notice of the masses. A song from that album called “Bush Killa,” about assassinating then-President George H.W. Bush, and another one about revenge killings of police officers called “Coffee, Donuts and Death,” got him attention from the Secret Service and dropped from his label.

But that didn’t stop Paris, who continues to release albums, including this fall’s Pistol Politics, and to rail against injustice in his rhymes.

See http://theciphershow.com/episode/136/ for full show notes and comments.

Take the ride of a lifetime with Birmingham Children's Hospital.

Former patient back on his bike for Velo.

Wavesfactory has announced the release of an accordion collection of Native Instruments Kontakt. Le Parisien is based on three accordions, with a faithful recreation of the sound and behavior of the real instruments. The library features Rouge, Blanc and Noir accordions, each one of them sampled with all registers, giving different sound characteristics, and mechanical […]

The post Wavesfactory releases Le Parisien virtual accordion library for Kontakt appeared first on rekkerd.org.

The COVID-19 pandemic is a situation most Americans alive today have not experienced. It’s challenged our American freedoms ranging from how we worship, work, educate, congregate, socialize, shop, vacation, and grieve. As a nation we take pride in our capitalistic economic system. Over the last several weeks we’ve witnessed 401K’s lose value, the stock market crash, along with historic joblessness and unemployment applications. I applaud both sides of the aisle for getting the stimulus package out, which includes the CARES act. But it’s not enough. The long-term effects of this pandemic will be far reaching. As states share their data on new cases and death related to COVID-19; the reality of American racism is being exposed again. According to the Surgeon General, African-Americans comprise 35.7% of confirmed cases and 53.2% of deaths despite only representing 27% of the US population. The US Census Bureau states the white population of Chicago, IL is 49%, and 30% African-American. As

It’s been 10 years since the great housing bust and lending is back. Not everyone is getting a fair shot at getting a loan. In dozens of cities across the country, lenders are more likely to deny loans to applicants of color than white ones – even when you take into account how much money they make and how much they want to borrow.

This type of housing discrimination was outlawed 50 years ago but it’s making a comeback. On this episode of Reveal, we dig into the new redlining.

This episode features an interactive text-messaging tool that allows you to learn more about who gets conventional home loans where you live. To get started, text HOME to 202-873-8325.

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It’s been 10 years since the great housing bust and lending is back for some Americans, but not for others. In dozens of cities across the country, lenders are more likely to deny loans to applicants of color than white ones.

On this episode of Reveal, we dig into the new redlining.

Don’t miss out on the next big story. Get the Weekly Reveal newsletter today.

By all accounts, electric vehicles are the future. Right now, EV’s comprise a small percentage of the automotive marketplace. A new study from the Ecology Center in Ann Arbor shows the electric vehicles owners are paying far more in taxes and fees and that can serve as a disincentive to purchase. The center’s Charles Griffith joined WEMU’s David Fair for this week’s "Issues of the Environment" to share the study’s findings and discuss the need to create policy that will create tax parity for EV vehicles.

By all accounts, electric vehicles are the future. Right now, EV’s comprise a small percentage of the automotive marketplace. A new study from the Ecology Center in Ann Arbor shows the electric vehicles owners are paying far more in taxes and fees and that can serve as a disincentive to purchase. The center’s Charles Griffith joined WEMU’s David Fair for this week’s "Issues of the Environment" to share the study’s findings and discuss the need to create policy that will create tax parity for EV vehicles.

Forget spring and summer — in the world of fashion, the season is fall 2020. Do keep up, dear reader.

Hispanic people in King County are dying from COVID-19 at much higher rates than white people, according to a new study. The insight into the coronavirus’ uneven impact in King County comes into focus as people of color represent an increasing percentage of the county's COVID-19 cases. 

Hispanic people in King County are dying from COVID-19 at much higher rates than white people, according to a new study. The insight into the coronavirus’ uneven impact in King County comes into focus as people of color represent an increasing percentage of the county's COVID-19 cases. 

The French are facing social disparities in the face of the coronavirus pandemic. With long bread lines and tensions with police, the Paris suburbs are faring poorly under the lockdown.