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Daniel García, director del IDRD estuvo en 6AM de Caracol Radio explicando cómo van las adecuaciones para ser la sede del próximo mundial femenino sub-20

Nestor Rosanía estuvo en los micrófonos de Caracol Radio explicando las dinámicas del Tren de Aragua

En Caracol Radio estuvo Santiago Chamorro, presidente y director de General Motors Sudamérica, dando detalles sobre el futuro de la compañía

Augusto Rodríguez, director de la Unidad Nacional de Protección, entregó detalles en 6AM de la manera en la que se otorgan medidas de protección a los funcionarios del INPEC

En el programa 6AM de Caracol Radio, habló Jennifer Pedraza, representante a la Cámara, y afirmó que la implementación del nuevo modelo de salud de los maestros ha sido incumplida por el gobierno. 

Animated and unrelenting debut set from London electro-rock quartet.

OpenCoder is an open and reproducible code LLM family which matches the performance of Top-Tier Code LLM. We provide not just the final models, but also the reproducible training data, the complete data processing pipeline, rigorous experimental ablation results, and detailed training protocols for open scientific research.

Business Design. Een up-and-coming discipline. En dat is niet vreemd. De opkomst van Business Design kun je niet los zien van het huidige business klimaat. Technologische en sociale ontwikkelingen volgen elkaar in hoog tempo op. Er is simpelweg geen tijd meer om eindeloos te sleutelen aan producten en diensten voordat ze naar de markt gaan. […]

Shaun Ross discusses his #InMySkinIWin movement.

The growing Hispanic populations in Colorado and the U.S. and their increasing buying power are the focus of Ahorra Mucho.

I recently published It’s Time to Make Important Upgrades to Our Mediation Curriculum, which notes significant changes in American mediation practice in the past five decades and suggests that law school faculty upgrade our mediation instruction accordingly. Modern Mediation Practice in American Legal Cases is a two-page summary of that article, which was published in … Continue reading Modern Mediation Practice in American Legal Cases →

[Written by Stephen Wright] Aspiring model Nalia Mitchell had the experience of a lifetime strutting down the catwalk at the recent New York Fashion Week Festival. Mitchell was among a handful of Bermudians who successfully applied for the Model Experience, which allowed participants to walk the runway, connect with brands and designers, share the stage […]

Bermudian Aliana King has been featured by British beauty brand Charlotte Tillbury as a model for the company’s skin care products. Ms. King has also appeared in a number of other campaigns for well-known brands, including David Yurman, SKKN, FREDDY WR.UP, Nordstrom x Nike [NxN], Skims, Redken, L’Oréal, Aveda, Garnier, Maybelline, and Allure, as well as style magazines including Elle Australia, Vogue Mexico, Vogue Arabia, and Elle Mexico. […]

[Written by Stephen Wright] Asia Smith has described her experience on the runway at the recent New York Fashion Week Festival as a “breathtaking” experience. Ms Smith was among several Bermudians who successfully applied for the Model Experience, allowing participants to walk the runway, share the stage with A-List talent, connect with brands and designers, […]

Bermudian model Aliana King made an appearance in the Winter 2023 edition of C Magazine as a face of Chanel’s cruise collection of clothing. The roller skating-themed campaign, dubbed “Skate It Till You Make It,” sees Ms. King “taking the L.A.-inspired Chanel cruise collection for a spin.”  Ms. King has also appeared in a […]

A new facility — the Modern Gent Dapper Lounge and Spa — has opened in Hamilton. A spokesperson said, “Modern Gent Dapper Lounge and Spa, which opened its doors today at 19 Queen Street, is delighted to offer an exclusive haven for men, emphasizing its commitment to provide top-tier services that our well-deserved male community […]

[Written by Stephen Wright] Sancho Jackson has reflected on his “inspiring experience” strutting down the catwalk at the recent New York Fashion Week Festival. The 22-year-old was selected to participate in The Model Experience, a coveted programme that offers aspiring models the chance to walk the runway, collaborate with brands and designers, share the stage […]

Sancho Jackson has completed his second modelling assignment after walking the runway at the Fig Buffalo Cut and Sewn show at Seneca One Tower in Buffalo, New York, last weekend. Mr Jackson, who lives in Birmingham, England, was invited to model at the event by Austin Guyett, the designer behind By A Guy, whom the […]

Osud České pirátské strany, která v několika volbách za sebou dostala výprask, je příkladem selhání progresivistického politického modelu. Když pak nedávno premiér Petr Fiala vyhodil z vlády Ivana Bartoše za nezvládnutou digitalizaci stavebního řízení, prezentovali se Piráti sérií emotivních a dětinských prohlášení. Uraženě opustili koaliční kabinet a naivně si myslí, že je to zachrání před dalším propadem. Za předsedu si teď zvolili Zdeňka Hřiba, kterého Pražané v pozici náměstka a předtím primátora hlavního města skutečně nemusí.

1. New Model Predicts Intelligent Life Odds in Universe  Mirage News
2. Formula for alien life: Drake Equation gets a dark energy update  Cosmos

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It shouldn’t be a big story that a desktop computer has upgradeable internal storage, but with Apple’s cute new 2024 Mac mini, that’s exactly where we are. It’s possible to pop the SSD out after removing a screw, and then switch in a bigger one. We didn’t run into the software blocks we saw in the…

The City by the Bay will soon have a new leader, as Democrat Daniel Lurie was elected the next mayor of San Francisco on Nov. 7. Lurie, a political newcomer, beat a fellow Democrat, incumbent Mayor London Breed, to earn the city's top job. He won the mayoral race by a large margin; Lurie led…

Member of the European Central Bank (ECB) Governing Council and Bank of France Governor Francois Villeroy de Galhau indicated on Wednesday that more interest rate cuts could be on the horizon, noting ...

Join our daily and weekly newsletters for the latest updates and exclusive content on industry-leading AI coverage. Learn More Google DeepMind has unexpectedly released the source code and model weights of AlphaFold 3 for academic use, marking a significant advance that could accelerate scientific…

We've bought our first home, and we are so excited to remodel the kitchen! We're keeping our updates simple and on a budget, but the imact will be HUGE!

The post Mini Kitchen Remodel – The “Before” – Virginia Beach, VA appeared first on Joyful Abode.

This post may contain affiliate links. If you make a purchase through an affiliate link, the site author may receive a small commission. The mini kitchen remodel reveal Have you been on the edge of your seat, wondering how my DIY mini kitchen remodel turned out? Well, here we go! We didn’t do a full […]

The post Mini Kitchen Remodel – Bright & Airy AFTER (You’ll love it!) appeared first on Joyful Abode.

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Cybersecurity researchers have disclosed six security flaws in the Ollama artificial intelligence (AI) framework that could be exploited by a malicious actor to perform various actions, including denial-of-service, model poisoning, and model theft. "Collectively, the vulnerabilities could allow an attacker to carry out a wide-range of malicious actions with a single HTTP request, including

The post How Does a Modern Communist Girl Look Like? appeared first on English Russia.

A Princeton-led team of astrophysicists has measured a surprising value for the “clumpiness” of the universe’s dark matter.

Jacques R. Fresco, the emeritus Damon B. Pfeiffer Professor in the Life Sciences and an emeritus professor of molecular biology, died on Dec. 5. He served on Princeton's faculty for 53 years before retiring in July 2013.

In this talk, Graham Neubig will discuss a new frontier in AI models, vision-language models that understand the world's cultures. The talk will be in two parts. First, Neubig will discuss training of multilingual multimodal multicultural models that understand images and text, and have increased ability to answer culture-specific questions about multimodal data. Second, he will discuss work on "image transcreation", where models have been developed that can transform images to make them more relevant to a particular culture. This work has applications in a number of areas, such as cultural localization of educational materials (to accompany translated text). While these methods cover many languages, African and not, the talk will focus on examples specifically from the African context, and challenges we currently face therein.

A working group analyzing Nahuatl-language documents of the sixteenth to nineteenth centuries with a concentration on deciphering paleography and considering issues of translation. The workshop will commence with Mesoamerican Manuscripts held in the special collections of the Princeton University Library in support of the Translating Mesoamerica project that will provide increased accessibility and analysis of these archival treasures.

From the moment the phonograph was discovered, things began to move upwards, so that today, for very little money, we could have music and even find out the name of the song we are currently listening to, with one click. Modern technology has changed the ways of listening to music. Music has never been more ... Read more

The post How Modern Technology has Changed the Way we Listen to Music? appeared first on Star Two.

A lot has changed in 22 years.
( Photos: 1, Comments: 64 )

Lab-grown diamonds have emerged as a fascinating alternative to traditional, naturally occurring diamonds. These gems, created under controlled laboratory conditions, possess unique advantages that set them apart from their earth-mined counterparts. In this exploration, we will delve into the world of lab-grown diamonds, examining the processes behind their creation and the environmental and ethical considerations ... Read more

The post Lab-Grown Diamonds: A Modern Marvel appeared first on Star Two.

Engagement rings, symbols of love and commitment, have journeyed through time, evolving in design, material, and meaning. This evolution reflects changing fashion trends and deeper shifts in social norms, economic conditions, and technological advancements. From the ancient times when rings were simple iron bands to the present day when they embody intricate designs and diverse ... Read more

The post The Evolution of Engagement Rings: A Journey from Traditional to Modern Choices appeared first on Star Two.

In the 1700s, an enslaved man named Onesimus shared a novel way to stave off smallpox during the Boston epidemic. Here’s his little-told story, and how the Atlantic slave trade and Indigenous medicine influenced early modern science.

The movie was the first Nesher made after returning to Israel following a decade-long stint in Hollywood.

The best early Black Friday MacBook deals include all-time low prices on the latest MacBook Air models.

Shaping modern Britain: the role of African and Caribbean communities 24 October 2024 — 5:00PM TO 6:00PM Anonymous (not verified) 3 October 2024 Chatham House and Online

As part of Black History Month, this event celebrates the enduring contributions of African and Caribbean communities to the UK.

When British colonial rule ended, newly independent countries in Africa and the Caribbean retained influences such as the English language and governance systems modelled on that of the UK. Initially, these post-independence relations were largely marked by the UK’s soft power, shaping the nation-building processes in these regions.

Over time, however, this influence has become a two-way exchange. African and Caribbean cultures have profoundly shaped modern Britain – from music and food to sports, arts, literature and beyond. These evolving dynamics have not only enriched the UK’s cultural landscape but also provided significant benefits for diaspora communities, fostering a sense of belonging and promoting cultural exchange. Diaspora groups and civil society organizations have adeptly utilised these connections to advocate for their communities and advance their interests.

At this event, speakers will explore how African and Caribbean influences rose to prominence in the UK and how this cultural momentum can be harnessed to build stronger, forward-looking partnerships. By highlighting the shared histories and more vibrant present-day exchanges, this event will explore how these ties can be used to break down stereotypes, promote social cohesion, and contribute to a more inclusive future.

This event forms part of our series of events celebrating Black History Month, including a photo exhibition and drinks reception.

Hdac3 is a lysine deacetylase that removes acetyl groups from histones and additional proteins. Although Hdac3 functions within mesenchymal lineage skeletal cells are defined, little is known about Hdac3 activities in bone-resorbing osteoclasts. In this study we conditionally deleted Hdac3 within Ctsk-expressing cells and examined the effects on bone modeling and osteoclast differentiation in mice. Hdac3 deficiency reduced femur and tibia periosteal circumference and increased cortical periosteal osteoclast number. Trabecular bone was likewise reduced and was accompanied by increased osteoclast number per trabecular bone surface. We previously showed that Hdac3 deacetylates the p65 subunit of the NF-κB transcriptional complex to decrease DNA-binding and transcriptional activity. Hdac3-deficient osteoclasts demonstrate increased K310 NF-κB acetylation and NF-κB transcriptional activity. Hdac3-deficient osteoclast lineage cells were hyper-responsive to RANKL and showed elevated ex vivo osteoclast number and size and enhanced bone resorption in pit formation assays. Osteoclast-directed Hdac3 deficiency decreased cortical and trabecular bone mass parameters, suggesting that Hdac3 regulates coupling of bone resorption and bone formation. We surveyed a panel of osteoclast-derived coupling factors and found that Hdac3 suppression diminished sphingosine-1-phosphate production. Osteoclast-derived sphingosine-1-phosphate acts in paracrine to promote bone mineralization. Mineralization of WT bone marrow stromal cells cultured with conditioned medium from Hdac3-deficient osteoclasts was markedly reduced. Expression of alkaline phosphatase, type 1a1 collagen, and osteocalcin was also suppressed, but no change in Runx2 expression was observed. Our results demonstrate that Hdac3 controls bone modeling by suppressing osteoclast lineage cell responsiveness to RANKL and coupling to bone formation.

Synapse loss is associated with motor and cognitive decline in multiple neurodegenerative disorders, and the cellular redistribution of tau is related to synaptic impairment in tauopathies, such as Alzheimer's disease and frontotemporal dementia. Here, we examined the cellular distribution of tau protein species in human tau overexpressing line 66 mice, a transgenic mouse model akin to genetic variants of frontotemporal dementia. Line 66 mice express intracellular tau aggregates in multiple brain regions and exhibit sensorimotor and motor learning deficiencies. Using a series of anti-tau antibodies, we observed, histologically, that nonphosphorylated transgenic human tau is enriched in synapses, whereas phosphorylated tau accumulates predominantly in cell bodies and axons. Subcellular fractionation confirmed that human tau is highly enriched in insoluble cytosolic and synaptosomal fractions, whereas endogenous mouse tau is virtually absent from synapses. Cytosolic tau was resistant to solubilization with urea and Triton X-100, indicating the formation of larger tau aggregates. By contrast, synaptic tau was partially soluble after Triton X-100 treatment and most likely represents aggregates of smaller size. MS corroborated that synaptosomal tau is nonphosphorylated. Tau enriched in the synapse of line 66 mice, therefore, appears to be in an oligomeric and nonphosphorylated state, and one that could have a direct impact on cognitive function.