File: (L-R) "The Sarah Silverman Program" writer Harris Wittels, comedian Sarah Silverman, executive producer/head writer Dan Sterling and actress Laura Silverman, arrive at Comedy Central's Emmy Awards party at the STK restaurant Sept. 21, 2008 in Los Angeles.; Credit: Ethan Miller/Getty Images

Harris Wittels, a comedy writer who worked on "Parks & Recreation," has died at 30, the Los Angeles Police Department's Jane Kim tells KPCC.

Wittels was discovered by his assistant around 12 p.m., Kim said, and was already dead. Kim said that Wittels' death was a possible overdose, but that the Coroner's Office would determine the cause of death. Wittels had attended drug rehab twice.

Comedy Central, where Wittels worked on "The Sarah Silverman Program" and "Secret Girlfriend," confirmed Wittels' death, as did the comedy show he appeared at Wednesday night.

Comedy Central tweet

Meltdown Show tweet

Wittels was also well known for his @Humblebrag Twitter account and later book, helping to popularize the idea online of the false modesty of bragging while trying not to look like you're bragging.

Wittels had spoken about his struggles with addiction in places including Pete Holmes's podcast "You Made It Weird" in a November episode.

"I just really stopped caring about my life," Wittels said on "You Made It Weird," explaining how he got into doing drugs. "I just really started to think, well, if I'm only here for 80 years, then who cares if I spend it high or not?"

Wittels received his first big break when Sarah Silverman saw him performing comedy and gave him a job writing for her Comedy Central show.

Wittels also wrote for HBO's "Eastbound & Down," several MTV awards shows and the American Music Awards. He had a recurring role on "Parks & Recreation" and was a regular guest on the "Comedy Bang Bang" podcast.

Comedians, actors and fans mourned Wittels' death online.

Harris Wittels Storify

See Wittels in a scene from "Parks & Recreation":

Wittels on Parks & Recreation

Listen to Wittels on "Comedy Bang Bang":

Wittels on Comedy Bang Bang

This story has been updated.

This content is from Southern California Public Radio. View the original story at SCPR.org.

Coyle, M; Fortin, R. Geological Survey of Canada, Open File 9054, 2023, 1 sheet, https://doi.org/10.4095/332250
<a href="https://geoscan.nrcan.gc.ca/images/geoscan/gid_332250.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/gid_332250.jpg" title="Geological Survey of Canada, Open File 9054, 2023, 1 sheet, https://doi.org/10.4095/332250" height="150" border="1" /></a>

Coyle, M; Fortin, R. Geological Survey of Canada, Open File 9044, 2023, 1 sheet, https://doi.org/10.4095/332240
<a href="https://geoscan.nrcan.gc.ca/images/geoscan/gid_332240.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/gid_332240.jpg" title="Geological Survey of Canada, Open File 9044, 2023, 1 sheet, https://doi.org/10.4095/332240" height="150" border="1" /></a>

Coyle, M; Fortin, R. Geological Survey of Canada, Open File 9034, 2023, 1 sheet, https://doi.org/10.4095/332230
<a href="https://geoscan.nrcan.gc.ca/images/geoscan/gid_332230.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/gid_332230.jpg" title="Geological Survey of Canada, Open File 9034, 2023, 1 sheet, https://doi.org/10.4095/332230" height="150" border="1" /></a>

Coyle, M; Fortin, R. Geological Survey of Canada, Open File 9024, 2023, 1 sheet, https://doi.org/10.4095/332220
<a href="https://geoscan.nrcan.gc.ca/images/geoscan/gid_332220.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/gid_332220.jpg" title="Geological Survey of Canada, Open File 9024, 2023, 1 sheet, https://doi.org/10.4095/332220" height="150" border="1" /></a>

Coyle, M; Fortin, R. Geological Survey of Canada, Open File 9014, 2023, 1 sheet, https://doi.org/10.4095/332210
<a href="https://geoscan.nrcan.gc.ca/images/geoscan/gid_332210.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/gid_332210.jpg" title="Geological Survey of Canada, Open File 9014, 2023, 1 sheet, https://doi.org/10.4095/332210" height="150" border="1" /></a>

Coyle, M; Fortin, R. Geological Survey of Canada, Open File 9004, 2023, 1 sheet, https://doi.org/10.4095/332200
<a href="https://geoscan.nrcan.gc.ca/images/geoscan/gid_332200.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/gid_332200.jpg" title="Geological Survey of Canada, Open File 9004, 2023, 1 sheet, https://doi.org/10.4095/332200" height="150" border="1" /></a>

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New York — In response to fatal overdoses in the local construction industry, New York City’s health and buildings departments are teaming up to conduct outreach at worksites.

Elk Grove Village, IL — The American Medical Association, along with more than two dozen other organizations, has issued a list of recommendations to help end the nation’s epidemic of drug-related overdose and death.

Lexington, KY — Responding to an “alarming trend” of drug overdose deaths in the workplace statewide over a recent 18-month period, the Kentucky Injury Prevention and Research Center recently issued a hazard alert.

Surrey, British Columbia — For people who are prescribed opioids to treat injury-related pain, experiencing their injury on the job may have a “protective effect” against the risk of future drug overdose.

Washington — The approval of a second over-the-counter naloxone nasal spray for emergency treatment of a known or suspected opioid overdose is a “game-changer” for its lifesaving potential, the National Safety Council says.

Itasca, IL — The National Safety Council is raising awareness of over-the-counter naloxone nasal spray for emergency treatment of opioid overdoses in the workplace.

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Boston — Workers in Massachusetts who reported a job-related injury in the past 10 years were 35% more likely to have died of an opioid-related overdose, the state’s Department of Public Health says.

Boston — Unintentional overdoses accounted for more than 1 out of 4 workplace deaths in Massachusetts between 2021 and 2022, the state’s Department of Public Health reports.

Washington — Bipartisan legislation recently introduced in the House would direct OSHA to create employer guidance on acquiring opioid overdose reversal medication and training workers on its use.

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Scientists have identified a molecule that appears to restore normal breathing in mice following a large dose of fentanyl.

Metal–organic frameworks (MOFs) have garnered significant attention in recent years owing to their exceptional properties. Understanding the intricate relationship between the structure of a material and its properties is crucial for guiding the synthesis and application of these materials. (Scanning) Transmission electron microscopy (S)TEM imaging stands out as a powerful tool for structural characterization at the nanoscale, capable of detailing both periodic and aperiodic local structures. However, the high electron-beam sensitivity of MOFs presents substantial challenges in their structural characterization using (S)TEM. This paper summarizes the latest advancements in low-dose high-resolution (S)TEM imaging technology and its application in MOF material characterization. It covers aspects such as framework structure, defects, and surface and interface analysis, along with the distribution of guest molecules within MOFs. This review also discusses emerging technologies like electron ptychography and outlines several prospective research directions in this field.

Insufficient evidence exists to support claims that taking megadoses of dietary antioxidants, such as selenium and vitamins C and E, or carotenoids, including beta-carotene, can prevent chronic diseases, says the latest report on Dietary Reference Intakes (DRIs) from the Institute of Medicine of the National Academies.

A new report by the National Academies of Sciences, Engineering, and Medicine proposes a strategy that the U.S. Environmental Protection Agency (EPA) should use to evaluate the evidence of adverse human health effects from low doses of exposure to chemicals that can disrupt the endocrine system.

The U.S. should establish a new coordinated research program to investigate the impacts of exposure to low doses of radiation on human health, says a new report estimating that $100 million in funding will be needed annually for the next 15 years to answer key research questions.

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High doses of amphetamine-based medications for ADHD, like Adderall, are linked to an over five times higher risk of psychosis or mania.

Drug overdoses involving illegal opioids, hallucinogens, stimulants, and sedative psychotropic medications rose by 356% in Colombia between 2010 and 2021.

Drug overdoses involving illegal opioids, hallucinogens, stimulants, and sedative psychotropic medications rose by 356% in Colombia between 2010 and 2021.

Decrypting the molecular basis of cellular drug phenotypes by dose-resolved expression proteomics  Nature.com

Blister Packaging for Certain Immediate Release Opioid Analgesics for Treatment of Acute Pain – Docket No. FDA-2019-N-1845 as it relates to opioid packaging, and recently passed Substance Use-Disorder Prevention that Promotes Opioid Recovery and Treatment for Patients (SUPPORT) Act, passed in late 2018.

Anyone associated with pharmaceuticals and packaging is likely aware President Trump signed the SUPPORT Act recently. The Substance Use–Disorder Prevention that Promotes Opioid Recovery and Treatment for Patients and Communities Act, also known as SUPPORT for Patients and Communities Act, includes a specific address to the type of packaging that should be utilized to stem the tide on opioid addiction.

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China's Party Congress: a dose of foreign policy realism is needed The World Today mhiggins.drupal 11 October 2022

In the final article of three on the 20th Chinese Communist Party Congress, which opens on 16 October, Yu Jie argues that Beijing must show more pragmatism about Taiwan and the West.

How important is foreign policy at the congress?  

The political reports delivered to the delegates of the week-long 20th Chinese Communist Party Congress, which happens every five years, follow a Marxist-Leninist formula. Economics and the means of production form the base, while politics and society fill in the superstructure. 

We can expect sections on the work of the Chinese Communist Party (CCP), ideological discussion, economics, domestic politics, foreign affairs, cultural reform and social developments. Usually, the report prioritizes big domestic political issues.  

The political report typically sheds some light on the status of, and relationships between, senior party members. It can also provide insights into the political fortunes of various interest groups. The report acts as a summary of the party’s achievements and its plans – expressed as the lowest common denominator of consensus between competing factions. 

This year’s congress should be no different, and the political reshuffle that takes place is likely to signal how Beijing intends to rise to the many challenges at home and abroad. 

Given China’s growing power and its fraught relationship with the West, this year’s congress is expected to feature serious discussion on weighty foreign affairs issues affecting Beijing, and which will have long-lasting implications for the rest of the world.  

Which geopolitical issues will be priorities?  

When it comes to foreign affairs, China’s priorities rarely change. The CCP seeks to create a stable external environment to foster its domestic economic development. This conservative maxim was advocated in the 1980s by China’s then-paramount leader, Deng Xiaoping, and it will continue to guide Beijing’s relationships after this congress. 

While we don’t know the exact details of this year’s political report, we can expect discussion on relations with the US-led West, a possible shift in the relationship between Beijing and Moscow, and elaboration on China’s ties with the Global South.  

Notably, it’s likely that a separate chapter of the political report will see Taiwan treated alongside the special administrative regions of Hong Kong and Macau, signalling the party’s commitment to its claims over the contested island.  

Despite a chorus of nationalistic rhetoric surrounding the issue of Taiwan, Beijing will be careful not to stumble into an international conflict which risks causing colossal damage on all fronts. The choice of language on the so-called ‘Taiwan question’ in this political report will serve as a bellwether as to how, if at all, the party might fundamentally shift its views regarding Taiwan and deviate from the principle of ‘peaceful reunification’, the policy stated at every congress since 1979. 

How have China’s relations with the West worsened?  

President Richard Nixon’s visit to China in 1972, the first by an American president to the Communist nation, kicked off five decades of relative stability. However, as China’s global influence has grown, so have Washington’s fears.  

The relationship has transitioned from the cooperation and relative stability that existed under President George W. Bush and President Hu Jintao in the early 2000s, into one characterized by volatility and competition under Xi Jinping, Joe Biden and Donald Trump. These tensions are almost certain to continue in Xi’s likely third term. 

Elements of China’s relationship with the West, such as cooperation over military and aviation technology, are becoming far more competitive. At the same time, trade and investment, once viewed as strong ties, have been rapidly deteriorating – as seen, for example, by several major publicly listed Chinese state-owned enterprises and large private companies withdrawing from the New York Stock Exchange.  

Will Beijing stand by the Kremlin despite Russia’s invasion of Ukraine?  

At the same time, Beijing’s close relationship with Moscow and its lack of opposition to Russia’s war in Ukraine have put China in an awkward position. The CCP has realized that cooperation with its long-standing ally and neighbour must come with substantial limits to avoid undermining its own political priorities and interests.  

Russia’s recklessness may spur Xi and the CCP’s senior leadership to minimize the economic, financial and political risks associated with the Kremlin’s pursuit of war against a country aligned with, and supported by, the West.  

Will China continue to support its regional partners?  

On its ties with the Global South, Beijing began to rethink its Belt and Road Initiative (BRI) as the US-led Indo-Pacific strategy gained geopolitical momentum. Regions of Southeast Asia and South Asia received a lot of funding and resources for BRI projects, as seen with Chinese support for the China-Pakistan Economic Corridor.  

Xi also recently introduced the Global Development and Global Security initiatives, which the political report should flesh out. 

Beijing is fully aware that it can only prosper if its regional partners prosper, and it can only achieve resource security and border stability if its southern and western neighbours in Myanmar and Afghanistan cease to fight over land and resources. 

Chinese foreign policy over the last five years has been a strange combination of high-octane rhetoric and patient pragmatism. To respond to this contradiction, the congress could be used as an opportunity to inject a dose of realism.  

Read the two further articles in this series: the first is a guide to why the Chinese Communist Party Congress matters; the second discusses the key domestic policy themes that Xi Jinping is expected to outline at this year’s congress.