Strict protocols and limited community spread helped a Maine high school stay open for in person instruction when its first coronavirus case turned up.

In Kodiak, Alaska, a school district with deep ties to the U.S. Coast Guard has been walloped by the government shutdown with hundreds of families going without paychecks. And news of a deal to temporarily reopen the government was doing little to allay the community's anxieties.

Use #physnobel on Twitter to submit your questions. The 2014 Nobel Prize in Physics will be announced on Tuesday, October 7. Join guests Charles Day of Physics Today, Andrew Grant of Science News, Jennifer Ouellette of Cocktail Party Physics and Amanda Yoho of Starts With A Bang! as they discuss predictions for possible winners. Who are the best contenders, and who are the potential "dark horse" candidates? Which major physics finds of this year might stand a shot at a win in the future? Victoria Jaggard and Helen Thompson of Smithsonian.com will be your hosts for the event. Tune in on October 2, and submit your questions on Twitter. Charles Day is the Online Editor for Physics Today magazine. Follow him on Twitter @CSRDay Andrew Grant is the physics reporter for Science News magazine. Follow him on Twitter @sci_grant Jennifer Ouellette is a science writer and blogger at Cocktail Party Physics. Follow her on Twitter @JenLucPiquant Amanda Yoho is a graduate student in theoretical and computational cosmology at Case Western Reserve University and a blogger at Starts With A Bang! Follow her on Twitter @mandaYoho Victoria Jaggard is the science editor for Smithsonian.com. Follow her on Twitter @vmjaggard99 Helen Thompson is a science reporter for Smithsonian.com. Follow her on Twitter @wwrfd

Since 1970, Lakehead Public Schools has operated Kingfisher Lake Outdoor Education Centre just outside of Thunder Bay, Ont. The CBC's Matt Fratpietro spent a morning with students from École Elsie MacGill Public School to learn more about the forests that surround the city.

CAD and Documentation Solutions Enable U.K.-Based Company To Create Bath Fixtures For Safe, Easy Access

Leading UK pneumatic product maker is deploying SolidWorks Office Professional to help automate such vital business processes as billing, scheduling

U.K.-based electrical connector manufacturer speeds product development with 3D mechanical design and product data management software

U.K.

UK consultancy reduces design cycles by weeks, cuts prototyping costs, and designs better products for global clients like Virgin Mobile and Hasbro

Leading Event Showcasing “Love of Design” to Take Place February 12-15, 2012

A new report urges districts to pay close attention to how they choose and use technology for students who are not yet fluent in English.

First and second-year medical students at the Penn State College of Medicine participated in a simulated rope rescue of an injured climber.

A new U.S. Government Accountability Office report found that the needs of students with IEPS and those who are learning English-language skills were not often met after the pandemic struck.

“Inside Out 2” will be the featured film for the drive-in movie at Penn State York set for 8 p.m. Friday, Sept. 13. The film is free and open to the public. Guests can park in the lower parking lot area behind the Pullo Family Performing Arts Center on campus beginning at 6 p.m. 

Shah Rukh Khan is set to appear in a film titled King

WILMINGTON, Del. – Governor John Carney and the Delaware Division of Small Business announced Thursday more than $7.7 million in funding awards to seven organizations as part of the recovery effort for the travel, tourism, and outdoor recreation industries.  The funds are part of the Economic Development Administration’s (EDA) $750 million American Rescue Plan Travel, Tourism […]

Three illicit massage establishments (IMEs) were shut down in February, the first full month of operation for the DOJ’s first Human Trafficking Unit (HTU), Attorney General Jennings announced Thursday. “These investigations highlight a continuing pattern that we’ve seen time and time again: human trafficking often happens in plain sight,” said Attorney General Jennings. “These were […]

The Delaware Forest Service joined the Delaware Association for Environmental Education (DAEE) to observe “World Outdoor Classroom Day” by planting trees this week at Heritage Elementary in Red Clay School District and Allen Frear Elementary in Caesar Rodney School District. An outdoor learning place is “any place where meaningful experiences can be had in and with nature and the environment," according to DAEE.  “Outdoor learning places are especially beneficial to young students to develop the deep life-long appreciation for the natural world, our dependence on it, and its fragility. Outdoor learning places are often at schools but they can be at parks, churches, or even created in a backyard.” For information, go to http://daeeonline.org

Killens Pond State Park in Kent County will be host site for the 2024 Becoming an Outdoors-Woman (BOW) program the weekend of Oct. 4 to 6, DNREC announced, with registration opening Sept. 4. The three-day event is expected to sell out quickly, with registration closing Sept. 18.

Andhra Pradesh Deputy Chief Minister Pawan Kalyan has taken on his party's ally and state Home Minister Anitha, accusing her of incompetence. He warned that unless there is improvement, he would be forced to "take over the home department as well".

[COSATU] The Congress of South African Trade Unions (COSATU) is deeply concerned by the Minister for Communications and Digital Technologies, Mr. S. Malatsi's sudden withdrawal of the South African Broadcasting Corporation (SABC) SOC Ltd Bill from Parliament where it was being engaged upon by the National Assembly's Portfolio Committee: Communications and Digital Technologies.

[DA] It is a national embarrassment that the inability of the City of Johannesburg to supply water to its residents, business and public sector offices, has now led to the shutdown of operations at the Constitutional Court, on Constitution Hill in Braamfontein.

Australian data centre operator NEXTDC Limited is building its first overseas facility in Malaysia.

Nigeria Football Federation (NFF) Appeals Committee has ratified Kwara United promotion to the Glo Premier League. The Appeals Committee upheld an earlier ruling of its Disciplinary and Organising (O&D) Committee on the hotly contested promotion ticket between the Afonja Warriors and Ranchers Bees. The llorin-based side have now officially joined the trio, Wikki Tourists, 3SC and Gabros FC to the Nigerian top flight for the upcoming 2014/15 season. Supersport.com gathered that the decision was taken at the end of the committee’s meeting in Abuja on Wednesday. Kwara United and Ranchers Bees have been locked in the promotion battle since the […]

New Manchester United manager, Ruben Amorim, is ready to give a green light for the Premier League club to offload Joshua Zirkzee in January. The Red Devils are looking to send Zirkzee out on loan in January. Zirkzee only arrived at Old Trafford six months ago in a £36.5million transfer. The Dutchman was United’s first […]

EPL: Amorim ready to offload Man Utd striker in January

Manchester United legend, Rio Ferdinand has suggested that new manager, Ruben Amorim may have made a mistake in not keeping former interim manager, Ruud van Nistelrooy at the club. Amorim arrived at Man United on Monday to officially take charge at Old Trafford having been named Erik ten Hag’s permanent replacement a few weeks ago. […]

Man Utd: Rio Ferdinand identifies first mistake Amorim has made

Former Chelsea defender, Glen Johnson has told forward, Christopher Nkunku that he would be ‘mad’ to leave Stamford Bridge amid rumours Manchester United are interested in signing him. Johnson believes Nkunku can start to have a big impact at Chelsea if he stays fit. Nkunku joined Chelsea from RB Leipzig in 2023. The Frenchman made […]

EPL: You’d be mad – Glen Johnson advises Chelsea star against leaving club for Man Utd

The 29th session of the Conference of the Parties on climate change has officially kicked off in Baku, Azerbaijan, with the promise of striking yet another historic global climate deal and finance adaptation, gender responsive action and financing, and forgotten issues such as food waste are top on the agenda as every action is as […]

Title: STD Rates Continue to Climb in U.S.
Category: Health News
Created: 8/28/2018 12:00:00 AM
Last Editorial Review: 8/29/2018 12:00:00 AM

Title: STDs in Men
Category: Diseases and Conditions
Created: 4/4/2000 12:00:00 AM
Last Editorial Review: 7/8/2022 12:00:00 AM

Title: Yeast infections vs. STDs in Men and Women
Category: Diseases and Conditions
Created: 1/8/2020 12:00:00 AM
Last Editorial Review: 7/29/2022 12:00:00 AM

Many RNA-binding proteins (RBPs) contain low-complexity domains (LCDs) with prion-like compositions. These long intrinsically disordered regions regulate their solubility, contributing to their physiological roles in RNA processing and organization. However, this also makes these RBPs prone to pathological misfolding and aggregation that are characteristic of neurodegenerative diseases. For example, TAR DNA-binding protein 43 (TDP-43) forms pathological aggregates associated with amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD). While molecular chaperones are well-known suppressors of these aberrant events, we recently reported that highly disordered, hydrophilic, and charged heat-resistant obscure (Hero) proteins may have similar effects. Specifically, Hero proteins can maintain the activity of other proteins from denaturing conditions in vitro, while their overexpression can suppress cellular aggregation and toxicity associated with aggregation-prone proteins. However, it is unclear how these protective effects are achieved. Here, we used single-molecule FRET to monitor the conformations of the aggregation-prone prion-like LCD of TDP-43. While we observed high conformational heterogeneity in wild-type LCD, the ALS-associated mutation A315T promoted collapsed conformations. In contrast, an Hsp40 chaperone, DNAJA2, and a Hero protein, Hero11, stabilized extended states of the LCD, consistent with their ability to suppress the aggregation of TDP-43. Our results link single-molecule effects on conformation to macro effects on bulk aggregation, where a Hero protein, like a chaperone, can maintain the conformational integrity of a client protein to prevent its aggregation.

"Imagine you buy a pinball machine, and years later, you enter your den to go play it, only to discover that all the paddles are missing, the pinball and bumpers are gone, and the monitor that proudly displayed your unassailable high score is removed". As reported by Polygon, that's an argument put forth by a new lawsuit against Ubisoft, filed by two Californian players of The Crew. They're suing the company in a proposed class action lawsuit over shutting down the racing game's servers, rendering it unplayable.

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October marked the "biggest" sales month for supermarkets in the UK so far despite food price hikes.

The first ever full-scale demonstration of a nuclear reactor designed to passively cool itself in an emergency was a success, showing that it should be possible to build nuclear plants without the risk of dangerous meltdown

Computer code dating back to the 1960s is still vital to banks, airlines and governments, but programmers familiar with the language are in short supply. Now AI models are being trained to fill the skills gap

Express Sport writers have decided who should replace Gary Lineker

ALEXIS SANCHEZ returns to former club Arsenal tonight - and Manchester United fans are desperate to see him celebrate if he scores at the Emirates..

Here is a full list of titles releasing over the next two weeks on Netflix

LAHORE — Pakistan's Punjab province banned most outdoor activities and ordered shops, markets and malls in some areas to close early from Monday (Nov 11) to curb illnesses caused by intense air pollution. The province has closed educational institutions and public spaces like parks and zoos until Nov. 17 in places including Lahore, the world's most polluted city in terms of air quality, according to Swiss group IQAir's live ratings. The districts of Lahore, Multan, Faisalabad and Gujranwala have seen an unprecedented rise in patients with respiratory diseases, eye and throat irritation, and pink eye disease, the Punjab government said in an order issued late on Sunday. The new restrictions will also remain in force until Nov. 17. "The spread of conjunctivitis/ pink eye disease due to bacterial or viral infection, smoke, dust or chemical exposure is posing a serious and imminent threat to public health," the Punjab government said.