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How Common Are STDs? Most People Have No Clue

Title: How Common Are STDs? Most People Have No Clue
Category: Health News
Created: 2/25/2020 12:00:00 AM
Last Editorial Review: 2/25/2020 12:00:00 AM




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Are You Still a Postdoc? How My Scientific Identity Intersects with My Immigrant Status

ABSTRACT

Academics in non-tenure-track positions encounter a unique set of challenges on the road toward tenure. Institutionalized policies and lack of mentors are additional burdens for foreign scientists, resulting in representation differences. Becoming a scientist has been a personal and moving journey in which my multiple selves intersect and clash every now and again. My identity as a scientist is a life project and has intersected with my other identities: a young Latina immigrant in Western Europe. This crossroad has molded, and at times, challenged my participation in science.




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Detection of ctDNA from Dried Blood Spots after DNA Size Selection

Abstract
Background
Recent advances in the study and clinical applications of circulating tumor DNA (ctDNA) are limited by practical considerations of sample collection. Whole-genome sequencing (WGS) is increasingly used for analysis of ctDNA, identifying copy-number alterations and fragmentation patterns. We hypothesized that low-depth/shallow WGS (sWGS) data may be generated from minute amounts of cell-free DNA, and that fragment-size selection may remove contaminating genomic DNA from small blood volumes. Dried blood spots have practical advantages for sample collection, may facilitate serial sampling, and could support novel study designs in humans and animal models.
Methods
We developed a protocol for the isolation and analysis of cell-free DNA from dried blood spots using filter paper cards and bead-based size selection. DNA extracted and size-selected from dried spots was analyzed using sWGS and polymerase chain reaction (PCR).
Results
Analyzing a 50 μL dried blood spot from frozen whole blood of a patient with melanoma, we identified ctDNA based on the presence of tumor-specific somatic copy-number alterations, and found a fragment-size profile similar to that observed in plasma DNA. We found alterations in different chromosomes in blood spots from 2 patients with high-grade serous ovarian carcinoma. Extending this approach to serial dried blood spots from mouse xenograft models, we detect tumor-derived cell-free DNA and identified ctDNA from the originally grafted ascites.
Conclusion
Our data suggest that ctDNA can be detected and monitored in dried blood spots from archived and fresh blood samples, enabling new approaches for sample collection and novel study/trial designs for both patients and in vivo models.




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ctDNA Reveals Targetable Alterations [News in Brief]

In the plasmaMATCH trial, researchers performed circulating tumor DNA testing on patients with advanced breast cancer and matched those with ESR1, HER2, or AKT1 alterations to targeted therapies. Patients with HER2 and AKT1 mutations experienced response rates greater than 22% with durable benefit.




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Cần bán Shophouse CC An Thịnh, An Phú An Khánh, Quận 2, TDT 201,9m2, hướng ĐN, sổ đỏ, giá 20 tỷ

- Cần bán Shophouse chung cư An Thịnh, An Phú An Khánh, Quận 2. Tổng diện tích 201,9m2, đường 20m (mặt tiền đường Thái Thuận giao nhau với đường Nguyễn Quý Đức) hướng Tây Bắc, sổ hồng, giá 20 tỷ. - Vị trí đẹp nhất ở quận 2, thích hợp mở quán cafe, mini shop... Gần Metro, trường h...




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Báo cáo thị trường Batdongsan.com.vn

Các diễn biến về giá bán, tình hình giao dịch, phân bổ dự án, sự quan tâm của khách hàng với thị trường bất động sản... sẽ được phản ánh qua các bài viết do Ban Nghiên cứu thị trường và đội ngũ PV, Biên tập của Batdongsan.com.vn thực hiện. Thông tin trong bài viết dựa trên dữ liệu trực tuyến người dùng và khảo sát thực tế nên sẽ đem lại độ chính xác cao, giúp người mua, nhà đầu tư có cái nhìn tổng thể, khách quan về thị trường.




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Expert talk - Batdongsan.com.vn

Expert talk là chuỗi các chương trình đào tạo nhà môi giới bất động sản (BĐS) chuyên nghiệp do Batdongsan.com.vn tổ chức định kỳ. Bên cạnh mục đích trang bị những kiến thức chuyên nghiệp về ngành môi giới BĐS, chương trình còn tạo cơ hội cho các nhà môi giới được tham vấn trực tiếp bởi những chuyên gia, những tỷ phủ BĐS hàng đầu tại Việt Nam và khu vực Đông Nam Á. Đồng thời, chương trình còn là cầu nối giúp những nhà môi giới được giao lưu, gặp gỡ và phát triển các mối quan hệ trong ngành.




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Hướng dẫn đăng thông tin trên trang batdongsan.com.vn

Cho tôi hỏi cách đăng tin cho thuê nhà trên trang batdongsan.com.vn.




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Quy tắc chung khi đăng tin trên Batdongsan.com.vn

Nội quy đăng tin? Quy tắc phê duyệt bài? Những lỗi cần tránh khi đăng bài?




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Cho thuê nhà DT 60m2 x 4T tại Khuất Duy Tiến, gần Big C Trần Duy Hưng, Vincom TDH, TT Hội Nghị QG

Cho thuê nhà chính chủ làm văn phòng DT 60m2 x 4 tầng. Tầng 2,3,4 chia 2 phòng, tầng 1 thông suốt. Mặt tiền 5m, cách ngã tư Khuất Duy Tiến - Trần Duy Hưng 10m (nhà trong ngõ cách đường chính mười mét), Ô tô có thể đi vào trong nhà, ngõ rộng thoáng nhiều lối ra vào. Nhà gần Big C ...




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Cần bán đất mặt tiền 12m ngay chợ, trường học, sổ hồng riêng, thổ cư 100%, XDTD, giá 1.050 tỷ /nền

- Hình thật 100%. - Cơ sở hạ tầng hoàn thiện 100%. - Khu dân cư hiện hữu và đông đúc. - Bao quanh nhiều KCN, cách công viên Phú Lâm 20 phút đi xe. - Gần siêu thị, trường học cấp 1, 2, 3, chợ, bệnh viện. - Giá: 1.050 tỷ. - Diện tích: 100m2 (5*20m). - Sổ hồng riêng, thổ cư 100%, hỗ...




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TDArchitects




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CÔNG TY CỔ PHẦN STDECOR




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Man Utd to rival Jose Mourinho for transfer, Werner to Liverpool, Newcastle instruction



The summer transfer window is nearly upon us as Manchester United, Chelsea, Liverpool, Arsenal and the rest of the Premier League look to strengthen for whenever the new season starts. Express Sport brings you the latest updates throughout the day.




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Fortnite Party Royale Event COUNTDOWN: Start time, Epic Games Rewards and more



Fortnite Party Royale event starts soon. Here's everything you need to know including start times for Deadmau5, Dillon Francis and Steve Aoki - PLUS how to claim the many live event rewards available from Epic Games as they celebrate 350 million players.




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More than 1,000 queue for food in rich Geneva amid virus shutdown




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TDP chief urges PM Modi to set up scientific experts' committee to probe Vizag gas leak incident




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Haaland urged to make Liverpool move as former coach questions Man Utd & Real Madrid for missing out

Alf Ingve Berntsen, who worked with the teenage striker at Byrne FK, believes a heavyweight European outfit should already have signed the Norwegian





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Man Utd told they may have got Bruno Fernandes for €20m amid coronavirus pandemic

The Portuguese giants offloaded the midfielder in January in a deal worth up to €65m, but asking prices have since dropped due to the Covid-19 crisis





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More than 1,000 queue for food in rich Geneva amid virus shutdown

More than 1,000 people queued up on Saturday to get free food parcels in Geneva, underscoring the impact of the coronavirus epidemic on the working poor and undocumented immigrants even in wealthy Switzerland.




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Man Utd fans DESPERATE for Alexis Sanchez to CELEBRATE if he scores against Arsenal

ALEXIS SANCHEZ returns to former club Arsenal tonight - and Manchester United fans are desperate to see him celebrate if he scores at the Emirates..




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TD Bank warns it’s expecting $1.1 billion in loan-loss provisions for U.S. unit

TD also said it will have about $600 million of set-asides tied to U.S. credit cards




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Gas stoves making indoor air up to five times dirtier than outdoor air, report finds

Gas cookers making people sick and exposing tens of millions to air pollution levels that would be illegal if they were outside

Gas stoves are making people sick, contributing pollution that makes indoor air up to two to five times dirtier than outdoor air, according to a new report.

Related: Microplastics found in greater quantities than ever before on seabed

Continue reading...




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William and Kate wish Brits Happy Easter amid coronavirus shutdown

Follow our live coronavirus updates HERE Coronavirus: the symptoms




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Americans turn to competitive Major League Eating during coronavirus sport shutdown

With elite sport across the globe on pause due to the coronavirus pandemic, Americans are turning to competitive eating to fill the void.




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Countdown presenter Rachel Riley wins first round of libel case against former Corbyn aide

Countdown presenter Rachel Riley has won the first round of a High Court libel case against a former aide to Jeremy Corbyn.




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Brits 'to be allowed to spend more time outdoors' under phased lifting of coronavirus lockdown

Boris Johnson is set to allow Brits to spend more time outdoors in the first phase of rolling back the coronavirus lockdown, it has been reported.





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Fortnite Darkfire Bundle (PS4/XB1/Switch) $14.99 & BOGO Fortnite Figures at Best Buy - DotD

Fortnite Darkfire Bundle (PS4/XB1/Switch) $14.99  msrp $29.99

Amazon has the PS4 version for the same price.

 

BOGO Fortnite Figures

 

Other Fornite deals:

Buy any v-bucks card, get the SteelSeries - Arctis 1 Wireless Stereo Gaming Headset for PC for $59.99

 

 

Here's what the Darkfire Bundle includes:

https://www.epicgames.com/fortnite/en-US/darkfire

Spoiler
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    A look at how provinces plan to emerge from COVID-19 shutdown

    Provinces have been releasing plans for easing restrictions that were put in place to limit the spread of COVID-19. Here is what some of the provinces have announced so far: Newfoundland and Labrador Newfoundland and Labrador plans to loosen some public health restrictions in a series of




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    TD expects U.S. retail banking business to take $1.1B charge for bad loans

    Toronto-Dominion Bank says it expects to take a provision for credit losses related to its U.S. retail banking business of roughly $1.1 billion (US$800 million) in its second quarter due to the pandemic.




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    Looking for toilet paper, disinfecting wipes or hand sanitizer? Try bartering on Facebook and Nextdoor

    Welcome to the real sharing economy. Friends and neighbors set up trades on Facebook and Nextdoor for household essentials like toilet paper, eggs and bread.

          




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    Digital-friendly recession: How Big Tech got even bigger in the midst of a market meltdown

    Many analysts expected the stocks to fall back to earth when the next downturn came




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    Shanghai Disneyland Sells Out Of Tickets For Post-Shutdown Reopening

    Visitors' health status will be checked on a smartphone app before they enter the park. Once inside, they will be required to wear face masks at all times unless they are eating.




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    Ellen DeGeneres crew left 'distressed and outraged' over pay amid coronavirus shutdown, report claims

    US talk show host previously said she returned to the air to support her crew, who she said she 'loves and misses'




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    Sam Smith responds to backlash over 'quarantine meltdown' photo

    The singer said their post had been badly timed




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    Vanessa Feltz recreates her infamous Celebrity Big Brother meltdown

    We can all relate now...




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    Join the community: how Nextdoor app is helping to connect neighbours during Covid-19

    People are flocking to the hyper-local app to stay connected during the lockdown




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    The Letdown: a sweet patchwork of comforting stories for anyone feeling alone

    A comedy that never quite whinges about new motherhood, but is frank and self-deprecating about its difficulties

    I know this is a column about shows you recommend watching in isolation, but I’m not sure if this one is comforting or excruciating right now. Maybe both! But if you’re self-isolating with small children, it’s almost definitely the latter.

    The Letdown is the story of a new mum, Audrey (Alison Bell), struggling to cope with her changed circumstances. As the primary caregiver to her daughter Stevie, she’s largely confined to her home. She feels inadequate, out of control, confused, and frustrated as her previous life – friends, parties, a semi-stable career! – slips out of grasp.

    Related: Orphan Black: gripping sci-fi series shows that in dark times, family (or a 'clone club') prevails

    Related: The Bold Type: candy-coloured take on millennial women shines with hope and comfort

    Continue reading...




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    Transfer news LIVE: Tottenham join race for Hakimi and Coutinho, Kurzawa 'in Arsenal talks', Man Utd rumours

    Welcome to the Evening Standard's live blog covering the latest transfer news and rumours from the Premier League and beyond.




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    Transfer news LIVE: Kane and Haaland on Man Utd shortlist, Arsenal receive Tolisso boost, Chelsea latest

    Welcome to the Evening Standard's live blog covering the latest transfer news and rumours from the Premier League and beyond.




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    Mikel Arteta using shutdown to strengthen bond with Arsenal stars - 'I want them to trust me'

    Mikel Arteta says he is trying to use the coronavirus shutdown to strengthen his bond with his Arsenal players.




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    Transfer news LIVE: Paul Pogba to Real Madrid, Man Utd Sancho move, Gotze latest, Liverpool, Chelsea rumours

    Welcome to the Evening Standard's live blog covering the latest transfer news and rumours from the Premier League and beyond.




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    Transfer news LIVE: Harry Kane 'open' to Man Utd transfer, Grealish latest; Chelsea, Arsenal, Liverpool gossip

    Welcome to the Evening Standard's live blog covering the latest transfer news and rumours from the Premier League and beyond.




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    Roy Hodgson praises Crystal Palace community work during coronavirus shutdown

    Roy Hodgson has issued a lengthy message to Crystal Palace supporters during the coronavirus crisis, commending the club and players' community efforts and reaffirming the collective desire to finish the 2019-20 Premier League season.




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    Transfer news LIVE: Liverpool eye Mbappe deal, Aubameyang update, Chelsea want Mertens; Man Utd, Arsenal gossip

    Welcome to the Evening Standard's live blog covering the latest transfer news and rumours from the Premier League and beyond.




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    Spanish football shutdown: RFEF plans to fast-track lower leagues when season resumes after coronavirus

    Spanish Football Federation (RFEF) president Luis Rubiales has come up with a new proposal for a fast-track finish to the lower leagues in Spain once football is back under way following the current break due to coronavirus.




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    Transfer news LIVE: Haaland blow for Man Utd plus Sancho latest; Partey to Arsenal; Liverpool, Chelsea rumours

    Welcome to the Evening Standard's live blog covering the latest transfer news and rumours from the Premier League and beyond.




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    Transfer news LIVE: Werner to Liverpool update, Arsenal in Disasi talks, Man Utd eye Koulibaly; Chelsea gossip

    Welcome to the Evening Standard's live blog covering the latest transfer news and rumours from the Premier League and beyond.




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    Transfer news LIVE: Sancho, Grealish to Man Utd latest; Coutinho to Chelsea update; Arsenal, Liverpool rumours

    Welcome to the Evening Standard's live blog covering the latest transfer news and rumours from the Premier League and beyond.