Lots of people are very confused about the topic of Forgiveness in the Bible. This study looks at what the book of Acts teaches about forgiveness, and in this way, we see a glimpse of what the Bible teaches about forgiveness. This study is an excerpt from from my Gospel Dictionary online course.

For large electric power storage projects the cost of batteries has plummeted. 2008, when battery prices were 10 times higher than they are today. This advance is timely as photovoltaic electric power prices have dropped so far that in SoCal PV is causing a growing drop in mid-day demand and therefore a much bigger spike in evening demand. Therefore there's a growing need for a cheaper way to store power generated in mid day and deliver it in the evening. You can see how much solar power output surges each day in California by clicking on some of the Daily Renewables Watch links at the Cal ISO site (the organization that manages California's electric grid). The growing supply of wind...

Levodopa-induced dyskinesia (LID) poses a significant health care challenge for Parkinson’s disease (PD) patients. Amantadine is currently the only drug proven to alleviate LID. Although its efficacy in treating LID is widely assumed to be mediated by blockade of N-methyl-D-aspartate (NMDA) glutamate receptors, our experiments demonstrate that at therapeutically relevant concentrations, amantadine preferentially blocks inward-rectifying K+ channel type 2 (Kir2) channels in striatal spiny projection neurons (SPNs) — not NMDA receptors. In so doing, amantadine enhances dendritic integration of excitatory synaptic potentials in SPNs and enhances — not antagonizes — the induction of long-term potentiation (LTP) at excitatory, axospinous synapses. Taken together, our studies suggest that the alleviation of LID in PD patients is mediated by diminishing the disparity in the excitability of direct- and indirect-pathway SPNs in the on state, rather than by disrupting LTP induction. This insight points to a pharmacological approach that could be used to effectively ameliorate LID and improve the quality of life for PD patients.

Hypoxia-inducible factor (HIF) is strikingly upregulated in many types of cancer, and there is great interest in applying inhibitors of HIF as anticancer therapeutics. The most advanced of these are small molecules that target the HIF-2 isoform through binding the PAS-B domain of HIF-2α. These molecules are undergoing clinical trials with promising results in renal and other cancers where HIF-2 is considered to be driving growth. Nevertheless, a central question remains as to whether such inhibitors affect physiological responses to hypoxia at relevant doses. Here, we show that pharmacological HIF-2α inhibition with PT2385, at doses similar to those reported to inhibit tumor growth, rapidly impaired ventilatory responses to hypoxia, abrogating both ventilatory acclimatization and carotid body cell proliferative responses to sustained hypoxia. Mice carrying a HIF-2α PAS-B S305M mutation that disrupts PT2385 binding, but not dimerization with HIF-1β, did not respond to PT2385, indicating that these effects are on-target. Furthermore, the finding of a hypomorphic ventilatory phenotype in untreated HIF-2α S305M mutant mice suggests a function for the HIF-2α PAS-B domain beyond heterodimerization with HIF-1β. Although PT2385 was well tolerated, the findings indicate the need for caution in patients who are dependent on hypoxic ventilatory drive.

Apple has launched a new web page that brings together links and information about its online services for customers shopping from home during the global health crisis.


Titled "Everything you love about our stores is online," the new catch-all page links from the Apple.com home page and includes details about no-contact delivery options, Apple Specialist help, financing and credit options, Apple Trade In, Apple Card, order status checking, service and support.

The page also links out to "Today at Apple - At home," a series of fun how-to videos to help users get creative during the ongoing stay-at-home measures, and there's a series of category links for customers to explore products on Apple's online store.

Apple has been gradually re-opening its retail stores in countries where lockdowns have eased, although some are operating on limited hours.

Apple CEO Tim Cook last week said that Apple was going to reopen stores in Austria and Australia this week, and Apple's sole Apple Store in Vienna will be reopening on Tuesday, May 5.

We're still waiting to hear exactly when stores in North America will reopen, but Cook also said that Apple is planning to reopen a few stores in the U.S. starting in May. Store openings will be staggered, with Apple evaluating data that includes local guidelines and recommendations before reopening.
This article, "New Apple Web Page Directs Customers to Its Online Shopping Services" first appeared on MacRumors.com

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Glenn Greenwald predicts over the next four years that "it's all going to get much worse", with President Obama shifting politically more to the right while the Democratic base continues to support him. Continue reading →

Jimmy Dore: The intelligence agencies have been releasing the reports to convince us that we should be upset at Russia because they hacked our election. First of all, who gives a shit if they did? The United States tapped Angela Merkel’s … Continue reading →

IBM announced today that Acrow, one of Australia’s leading suppliers of scaffolding and formwork for the construction industry, has selected IBM and IT Easy , to implement a total infrastructure refresh built around IBM Cloud, mobile, and network technology.

IBM today announced that Vissensa, a UK-based managed service provider (MSP), has taken delivery of the IBM Enterprise Cloud System, which will help the company offer new and improved cloud services to its customers.

The IBM board of directors today elected Joseph R. Swedish and Frederick H. Waddell to the board.

IBM today announced that Westpac New Zealand, part of one of the world’s largest financial services institutions, has selected IBM’s private cloud technology to support its goal to be New Zealand’s leading digital bank. The new five year agreement is part of an extensive services and technology contract which includes Westpac migrating some of its business critical IT systems into IBM’s state-of-the-art Auckland data centre, enabling enhanced customer service.

IBM announces agreement to move the New Zealand Ministry of Health to IBM Cloud Managed Infrastructure for New Zealand Government.

IBM's World Community Grid, a worldwide network of PC owners helping scientists solve humanitarian challenges, today announced several computing projects aimed at developing techniques to produce cleaner and safer water, an increasingly scarce commodity eluding at least 1.2 billion people worldwide.

IBM and Rail Projects Victoria keeping the $11B Metro Tunnel on track

IBM today announced that WesTrac Pty Ltd, an industrial machinery supplier headquartered in Perth, has selected IBM to design and implement a Portable Modular Data Center (PMDC) solution to provide the company with a flexible, cost-effective data centre to meet its immediate business needs as well as support future IT growth.

IBM (NYSE: IBM) today announced it has been awarded a $23.6M dollar contract with the National E-Health Transition Authority (NEHTA) to design and build Australia’s National Authentication Service for Health (NASH) project.

IBM today announced the signing of a new five-year infrastructure services agreement with The Westpac Group, which marks a key step in Westpac’s technology transformation program.

IBM today announced a new analytics-based tool for its data centre consolidation and relocation services which help clients gain up to 50% operational savings from the consolidation of IT assets and data centres.

IBM (NYSE: IBM) today announced that the University of Melbourne, a world class research university, has selected IBM to design and install a high efficiency, high density cooling solution to support new IT initiatives such as Cloud and Research computing, in its new data centre, Data Hall 2.

Melbourne-based start-up Level35 is using Watson, the cognitive computing platform developed by IBM (NYSE: IBM), and IBM Cloud to help public-sector project managers improve how they communicate within some of the largest government agencies in Australia.

IBM (NYSE: IBM) today announced its role as the systems integration partner for the $100 million Smart Grid, Smart City initiative led by the EnergyAustralia consortium. IBM will play a pivotal role, as a member of the consortium, in the development of Australia’s first smart grid network, following the formal contract signing of the deal between EnergyAustralia and the Australian Government.

The Australian Customs and Border Protection Service (ACBPS) has implemented an advanced passenger analysis solution with IBM to improve border security.

INPEX selects IBM to manage operation critical apps in Australia

Harrisburg University proudly announces, in a press release: HU facial recognition software predicts criminality A group of Harrisburg University professors and a Ph.D. student have developed automated computer facial recognition software capable of predicting whether someone is likely going to be a criminal. With 80 percent accuracy and with no racial bias, the software can […]

If you use some type of analytics to monitor your websites performance you’ve probably seen its bounce rate. So what is bounce rate exactly? It can be defined in a couple of different ways; it can either be an indicator to the number of visitors who view only one page of your site and leave. Or the number of visitors who leave your site after a short amount of time (usually only a couple of seconds)............

From the darkness emerges a boot. An old leather, steel-toed, work boot. It shouldn’t be there resting on the seafloor nearly two kilometers deep. I’m…

This evaluation report is based on feedback from people living with dementia and carers who received an Individual Award from the Life Changes Trust. The Individual Awards Pilot Scheme was run in Argyll & Bute and Edinburgh in 2014-15 and aimed to provide a small amount of additional financial empowerment to a number of individuals whose lives have been affected by dementia, to help improve their well-being and quality of life. A secondary aim of the pilot scheme was to find out what people would spend the Award on when given relatively broad choice, and what benefit that might bring in the short and medium terms.

The Better Breaks funding programme is focused on improving the range and availability of short break opportunities for disabled children and young people, particularly those with multiple support needs, including short break opportunities that families can enjoy together, or which allow parents and siblings to have time away from their caring responsibilities. This is the summary report.

The Short Breaks Fund helping to make breaks better and brighter for unpaid carers and cared-for people in Scotland. Launched in 2010 for one year, the fund has now been running for five years and has proved to be a lifeline for many carers. During the past five years the Scottish Government, through Shared Cared Scotland has distributed 12,547,409 to 697 projects to deliver innovative, tailor made breaks to groups and individuals.

The internet is reacting to comments made by Donald Trump during a COVID-19-related press briefing held yesterday. Trump claimed that the virus could be treated by bringing "light inside the body" or injecting a disinfectant. Thankfully medical professionals were quick to denounce these claims, and people on the internet have since been creating some excellent memes on the matter. 

This should go without saying, but please don't inject yourself with disinfectant, y'all.

https://t.co/tjwD5HQWM4 Valuing retirement #housing: explores economic effects of specialist housing 4 #olderpeople Strategic Society Centre

Workers in the bottom quintile of the wage distribution experienced a 35 percent employment decline while those in the top quintile experienced only a 9 percent decline. Large differences across the wage distribution persist even after conditioning on worker age, business industry, business size, and worker location. As a result, average base wages increased by […]

The post Facts about labor markets ouch, when are rising wages bad edition appeared first on Marginal REVOLUTION.

It's true what they say. Not all heroes wear capes. They wear gloves, masks, and gowns. That's especially true these days.

Source: Reuters

LONDON (Reuters) - A young boy chooses a nurse as the superhero he wants to play with over Batman and Spiderman in a new artwork by Banksy that encapsulates the gratitude Britons have felt toward the country’s National Health Service during the coronavirus crisis.

The painting by the secretive street artist was unveiled at University Hospital Southampton, in south England, on Wednesday.

An image of the work was also posted on Banksy’s Instagram page with the caption “Game Changer”.

Hospital chief executive Paula Head said: “So proud to reveal this amazing piece of art ‘Painting for Saints’, created by #Banksy as a thank you to all those who work with and for the NHS and our hospital.”

“An inspirational backdrop to pause and reflect in these unprecedented times,” she added on Twitter.

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Around the planet, a loosely knit but closely woven band of amateurs monitor the whereabouts of satellites — be they secretive spacecraft, rocket stages, orbital debris or lost space probes.

Request for Proposals are now open for three Fire Protection Research Foundation (FPRF) research projects.   First Responder Small Unmanned Aerial Systems (sUAS) Operations Training: Baseline Materials & Usage Assessment: The overall goal of

As SARS-CoV-2, the novel coronavirus pathogen that causes the illness COVID-19, sweeps across the globe, social distancing measures are noticeably impacting the environment. Consequently, both the preservation and restoration of environmental quality are experiencing a new normal as the pandemic continues.[...]

The Xuan Hoa commune in the Lao Cai province of northwest Vietnam is, like much of the surrounding area, a region that has suffered from economic hardships in the past. A large number of households in Xuan Hoa live in extreme poverty, including many of the school district’s 78 students aged 6 to 11 years old. The new Dao school by 1+1>2 Architects was completed in 2019 to provide provide education to the area’s children in first through fifth grades.[...]

Two severe security flaws have been discovered in the open-source SaltStack Salt configuration framework that could allow an adversary to execute arbitrary code on remote servers deployed in data centers and cloud environments. The vulnerabilities were identified by F-Secure researchers earlier this March and disclosed on Thursday, a day after SaltStack released a patch (version 3000.2)

Every two weeks we pick our favorite 15 projects that Craftster readers have voted for with the “This Rocks!” button. Here are our latest picks which were lovingly and painstakingly chosen (so many amazing projects to choose from!), this time by rackycoo. We hope you enjoy them! Baby Carrots the Mini-Pinata by EriChanHime supernatural pumpkin […]

Since February 2009, we have chosen 15 current Featured Projects from around Craftster. Ten years of amazing featured projects. Today, though, in lieu of the site closing, we are bringing you the final collection of Featured Projects for Craftster — ever. And today, we are not featuring current projects. Today, we are featuring a collection […]

On this week's show we have two guests for you. First up, Jason Shardlow-Wrest, a dispute resolution/litigation lawyer at Linklaters to chat about the difficult issue of player contracts. Some of them expire on June 30th, but proposals from FIFA to extend them are just guidelines right now. We chat about the implications on clubs, players and agents, wonder about what might happen loan players like Dani Ceballos, as well as the transfer market and players whose contracts expire next year that Arsenal might have wanted to sell this summer.

Then, for a lovely, long rambly-chat I'm joined by comedian, writer and podcaster Adam Buxton. We talk about his brand new audiobook which is out now, podcasting, being nervous when interviewing famous people like Marc Maron, my anxiety dream ahead of this interview, doing silly voices, plus lockdown TV viewing – some of it quite saucy – and loads more besides.

LINKS

Read Jason's blog on contracts here - and the Linklaters sports blog here.

Adam's Audiobook is available from Audible – and you can find his podcast at acast.com/adambuxton or in all good podcast apps!

See acast.com/privacy for privacy and opt-out information.

4life Products are great. But lets face it you want to be able to sell as much of them as possible. Obviously the more you sell the more you make. However there are challenges selling 4life Products, right? Well this article will give you some tips to prosper.

The post 5 Post-Processing Effects to Instantly Enhance Your Photos appeared first on Digital Photography School. It was authored by Jaymes Dempsey.

Do you want some quick and easy ways to improve your images with post-processing effects? Look no further. Because this article will give you 5 excellent post-processing effects to take your photos to the next level, instantly. And best of all: You can use them in pretty much any editing program and on pretty much […]

The post 5 Post-Processing Effects to Instantly Enhance Your Photos appeared first on Digital Photography School. It was authored by Jaymes Dempsey.

The post Weekly Photography Challenge – Everyday Objects appeared first on Digital Photography School. It was authored by Caz Nowaczyk.

Since many of us are still limited to where we can go, this week’s photography challenge topic is the EVERYDAY OBJECTS! Everyday objects can be anything from a cup filled with coffee, TV remote, shoes, pens, computer mouse to a guitar pick. You get the picture! Get creative with them, either with the photography style […]

The post Weekly Photography Challenge – Everyday Objects appeared first on Digital Photography School. It was authored by Caz Nowaczyk.

Focusing on urbanization as a key driver of environmental change in the 21st century, researchers at Princeton have created a framework to understand and compare cities’ food systems and their effects on climate change, water use and land use. The research will allow planners to estimate the impact of a city’s food system and evaluate policy actions.

Princeton researchers have been awarded a National Science Foundation RAPID grant to study how anxiety about COVID-19 influences how we learn and share information about the pandemic.