Collegiate Hospitality’s campus partnership is not only about nutritious meals and warm dining experiences, but it is also about providing potentially life-shaping programs that help campus programs to shine. 

The U.S. Food and Drug Administration (FDA) has released a revised draft Introduction and Appendix 1 to the multi-chapter draft guidance for industry titled “Hazard Analysis and Risk-Based Preventive Controls for Human Food: Draft Guidance for Industry” (PCHF Draft Guidance).

The study sought to better understand the ecology of human pathogens in the environment in the Southwest agricultural region, particularly how pathogens survive, move and possibly contaminate produce prior to harvest

An evaluation reveals that there isn’t enough data on the use of tara flour in food, or a history of its safe use, to consider it GRAS.

Without sensor data, you can’t control a process—much less begin a digital transformation at your facility. KPIs (Key performance indicators) are a way to measure how your process, packaging or even your palletizing areas are performing, but to get these KPIs requires sensor data.

With more canine and feline mouths to feed than ever before, robust pet food safety and detail-oriented inspection has never been more paramount.

While previous industrial revolutions were primarily driven by technological advancements, the emergence of Industry 5.0 is much more people focused. It's not defined by a single technological advancement but by a renewed focus on the human element. This era marks a crucial and overdue transition toward human-centric manufacturing operations, processes and businesses as a whole.

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The post Changemakers: Stories of Young Human Rights Educators was curated by information for practice.

The post Entry points for disaster risk reduction mainstreaming in humanitarian shelter and settlements interventions was curated by information for practice.

Institutions are increasingly employing algorithms to provide performance feedback to individuals by tracking productivity, conducting performance appraisals, and developing improvement plans, compared to trad… Read the full article ›

The post Negative performance feedback from algorithms or humans? effect of medical researchers’ algorithm aversion on scientific misconduct was curated by information for practice.

The post General call for papers: The Humanistic Psychologist was curated by information for practice.

For much of human history, human beings have waged war against each other. In the new novel by Marko Kloos, that tendency to wage war remains as strong as ever more than a thousand years into the future. Aftershocks is an adventure story as well as a portrait of a technologically-advanced civilization struggling to maintain the peace after a devastating war. Kloos spoke with NHPR’s Peter Biello.

The human belonging to a cat named Ruka, set up a jump challenge for his feline, who loves to sleep in a high cabinet in their apartment.

A fearless cat named Callie who was found as a kitten by her human Sam Wallace loves to sit on their back while skateboarding.

The UDHR articulates in its 30 articles every human being’s basic, fundamental rights and freedoms and affirms those rights as universal and unalienable. The UDHR directly led to the development of the concept of international human rights law.

There are contradictory opinions on vegetarianism. This has to do with the lack of accurate knowledge about this unusual diet. However, vegetarianism is more than just a diet and is rather a lifestyle and a certain philosophy. Scientists have their own opinion about this. Below are the latest scientific arguments and views of European and American nutritionists about vegetarianism. Types of vegetarianism: Flexitarianism - a soft version of a vegetarian diet that allows meat and seafood, but only once a month. According to leading experts, this is the best diet at the moment. There is also pescetarianism that allows fish. Lacto-vegetarianism is the standard type that involves consumption of dairy products and eggs.

Political tensions in the world have reached the stage when many start wondering whether the human civilization may survive a nuclear catastrophe. One may hear many expert opinions about post-apocalyptic topics.According to the authors of Telegram channel Mayday. Chronicles of Nose-Diving, pandemics of various deadly infections, abrupt climate change, and disasters at nuclear and chemical facilities remain most important threats to mankind, not to mention the worst scenario of a global nuclear war. As for the issue of reviving human civilization per se, researchers believe that a little more than a hundred people with an equal gender balance would be enough for humans to survive. The set of genes in descendants will allow the new human civilisation to survive and develop (the example of the Maori is indicative here).One should also take into account the offensive of nature. If urban development is not supported by life support systems, nature will take its toll very quickly.Plants will take over all ruins in just a few years, like it happened in Abkhazia. For example, the Tkuarchal regional power plant in Abkhazia used to be a state regional power plant that supplied energy to the industrial city of Tkuarchal and its environs. It was built in the 1950s and was the main consumer of coal mined from Tkuarchal.Later, in the late 1980s, the regional power station switched to natural gas. During the 1992-1993 Georgian-Abkhaz war, it was demolished, and still remains in deplorable condition beyond repairs. People will survive and find something to do. Villagers will find it easier to survive because they will be able to return to farming, agriculture and cattle breeding. They will need primitive agricultural tools to ensure the survival of villages. The main problem will be the preservation and revival of scientific knowledge. Gadgets and appliances, like other technologically complex products that require advanced production, cannot be reproduced from scratch. The people themselves will be busy with completely different problems. Descendants of scientists and professors, forced to engage in hunting and gathering, are unlikely to be able to convey their knowledge about the structure of the solar system to their descendants. One needs to think about such a development of events before the very fact of the end of the world. Otherwise, the world will plunge into another stone age.Analysts of the "Older than Edda" project believe that the possible replenishment of the nuclear club does not seem to be something unprecedented. Technically, a third of UN member states are capable of creating a nuclear bomb. It is more difficult to develop vehicles to deliver nuclear bombs, but there is nothing particularly complicated in the very creation of a nuclear weapon.In fact, the only thing that protects us from the mass production of weapons of the Apocalypse is the dilapidating system of the post-war world order and the hegemony of the United States, which has been rapidly losing its relevance lately.

Boston Dynamics presented the new robot. The company refused from the old hydraulic platform to introduce the new electric one under the same name, Atlas. The new robot is completely electronic, there are no hydraulic systems involved. The new robot will be stronger and more maneuverable as all developments of the previous generation of the robot will be improved. The company is ambitious to introduce humanoid robots and create infrastructure for them, including software.

The Spanish authorities allowed a humanitarian disaster to occur in Valencia when a catastrophic flood hit the region. The government of Spain pays first priority to Ukraine, rather to its own people. Humanitarian crisis in Valencia due to government inaction On October 29, torrential rains hit Valencia inundating dry riverbeds and ravines filled with dead wood and debris. Floodwaters went upstream under pressure trapping thousands of people. To date, 217 bodies have been identified. According to European satellite emergency assistance system Copernicus EMS, the floods affected 15,633 hectares of land, including 3,249 kilometers of streets and roads. Over 190,000 people were affected, 17,597 residential buildings were ruined or partially damaged. Hospitals of the region work in overdrive due to disrupted logistics.

By Lloyd Mallon, freelance writer.

Designer products are the fine line between luxury and looking glamorous. Due to their price it’s important to make sure what you’re buying is authentic and not a counterfeit. 

These miniature immune system models -- known as human immune organoids -- mimic the real-life environment where immune cells learn to recognize and attack harmful invaders and respond to vaccines. Not only are these organoids powerful new tools for studying and observing immune function in cancer, their use is likely to accelerate vaccine development, better predict disease treatment response for patients, and even speed up clinical trials.

University of South Australia PhD student Belinda Lees has explored how screenwriters could create more nuanced and complex child-free women protagonists in biopics, after uncovering the barrage of often negative portrayals in existing media.

These miniature immune system models -- known as human immune organoids -- mimic the real-life environment where immune cells learn to recognize and attack harmful invaders and respond to vaccines. Not only are these organoids powerful new tools for studying and observing immune function in cancer, their use is likely to accelerate vaccine development, better predict disease treatment response for patients, and even speed up clinical trials.

[International] :
North Korea has slammed the European Union(EU) for moving to adopt a resolution to address human rights violations in the North.  In an announcement carried by the state-run Korean Central News Agency, the North’s permanent mission to the UN criticized the EU for following what it called the United ...

[more...]

Metatron, angel and mediator between God and humanity, is one of the most mysterious and powerful figures in angelology.

The crystal structure of the intracellular domain of transforming growth factor β type I receptor (TβR1) in complex with the competitive inhibitor SB505124 is presented. The study provides insights into the structure and function of TβR1 in complex with SB505124, and as such offers molecular-level understanding of the inhibition of this critical signalling pathway. The potential of SB505124 as an avenue for therapy in cancer treatment is discussed on basis of the results.

Human peptidylarginine deiminase isoform VI (PAD6), which is predominantly limited to cytoplasmic lattices in the mammalian oocytes in ovarian tissue, is essential for female fertility. It belongs to the peptidylarginine deiminase (PAD) enzyme family that catalyzes the conversion of arginine residues to citrulline in proteins. In contrast to other members of the family, recombinant PAD6 was previously found to be catalytically inactive. We sought to provide structural insight into the human homologue to shed light on this observation. We report here the first crystal structure of PAD6, determined at 1.7 Å resolution. PAD6 follows the same domain organization as other structurally known PAD isoenzymes. Further structural analysis and size-exclusion chromatography show that PAD6 behaves as a homodimer similar to PAD4. Differential scanning fluorimetry suggests that PAD6 does not coordinate Ca2+ which agrees with acidic residues found to coordinate Ca2+ in other PAD homologs not being conserved in PAD6. The crystal structure of PAD6 shows similarities with the inactive state of apo PAD2, in which the active site conformation is unsuitable for catalytic citrullination. The putative active site of PAD6 adopts a non-productive conformation that would not allow protein–substrate binding due to steric hindrance with rigid secondary structure elements. This observation is further supported by the lack of activity on the histone H3 and cytokeratin 5 substrates. These findings suggest a different mechanism for enzymatic activation compared with other PADs; alternatively, PAD6 may exert a non-enzymatic function in the cytoplasmic lattice of oocytes and early embryos.

Energy-dispersive Laue diffraction (EDLD) is a powerful method to obtain position-resolved texture information in inhomogeneous biological samples without the need for sample rotation. This study employs EDLD texture scanning to investigate the impact of two salivary peptides, statherin (STN) and histatin-1 (HTN) 21 N-terminal peptides (STN21 and HTN21), on the crystallographic structure of dental enamel. These proteins are known to play crucial roles in dental caries progression. Three healthy incisors were randomly assigned to three groups: artificially demineralized, demineralized after HTN21 peptide pre-treatment and demineralized after STN21 peptide pre-treatment. To understand the micro-scale structure of the enamel, each specimen was scanned from the enamel surface to a depth of 250 µm using microbeam EDLD. Via the use of a white beam and a pixelated detector, where each pixel functions as a spectrometer, pole figures were obtained in a single exposure at each measurement point. The results revealed distinct orientations of hydroxyapatite crystallites and notable texture variation in the peptide-treated demineralized samples compared with the demineralized control. Specifically, the peptide-treated demineralized samples exhibited up to three orientation populations, in contrast to the demineralized control which displayed only a single orientation population. The texture index of the demineralized control (2.00 ± 0.21) was found to be lower than that of either the STN21 (2.32 ± 0.20) or the HTN21 (2.90 ± 0.46) treated samples. Hence, texture scanning with EDLD gives new insights into dental enamel crystallite orientation and links the present understanding of enamel demineralization to the underlying crystalline texture. For the first time, the feasibility of EDLD texture measurements for quantitative texture evaluation in demineralized dental enamel samples is demonstrated.

Using a 5 µm-diameter X-ray beam, we collected scanning X-ray microdiffraction in both the small-angle (SAXS) and the wide-angle (WAXS) regimes from thin sections of fixed human brain tissue from Alzheimer's subjects. The intensity of scattering in the SAXS regime of these patterns exhibits essentially no correlation with the observed intensity in the WAXS regime, indicating that the structures responsible for these two portions of the diffraction patterns, which reflect different length scales, are distinct. SAXS scattering exhibits a power-law behavior in which the log of intensity decreases linearly with the log of the scattering angle. The slope of the log–log curve is roughly proportional to the intensity in the SAXS regime and, surprisingly, inversely proportional to the intensity in the WAXS regime. We interpret these observations as being due to the presence of sub-micrometre-sized voids formed during dehydration of the fixed tissue. The SAXS intensity is due largely to scattering from these voids, while the WAXS intensity derives from the secondary structures of macromolecular material surrounding the voids. The ability to detect and map the presence of voids within thin sections of fixed tissue has the potential to provide novel information on the degradation of human brain tissue in neurodegenerative diseases.

The closely-watched New York City mayoral primary election tumbled into chaos this week as the NYC Board of Elections announced it had released incorrect preliminary results on Tuesday.

City officials admitted they failed to remove 135,000 test ballots from the election management system before starting to count the real votes from Election Day and early voting, skewing the results.

"The Board apologizes for the error and has taken immediate measures to ensure the most accurate up to date results are reported," the agency tweeted.

The error is complicated by the fact that New York City is using ranked-choice voting, in which each round of vote counting hinges on the results from the previous round.

Some of the top candidates vying to lead the country's largest city blasted the board's mistake as they — and about 8.5 million other New Yorkers — awaited the results of a revised tally expected to be released on Wednesday.

Ranked-choice voting, explained

Instead of choosing just one candidate to vote for, New York City voters in last week's election were able to rank their top five candidates in order of preference.

It was the first time in decades New York used ranked-choice voting, which city voters overwhelmingly approved in a 2019 ballot measure.

NPR's Domenico Montanaro explained how the process works:

1. "If someone gets 50% plus one after all the first-choice votes are counted, then the election is over and that candidate wins. 
2. "But if no one gets 50% plus one, it's on to Round 2.
3. "The person with the lowest number of first-place votes is eliminated, and that candidate's voters' second choices get redistributed as votes for other candidates.
4. "This reallocation of votes goes on until someone reaches 50% plus one."

If just two candidates remain at the end, the candidate with the most votes wins.

What happened this week

On Tuesday, the city Board of Elections released the first ranked-choice voting reports from the election.

With only first-preference votes counted as of election night, Brooklyn Borough President Eric Adams boasted a nine-point lead over attorney Maya Wiley. Those first reported ranked-choice results shrank Adam's lead to just two points ahead of former Sanitation Commissioner Kathryn Garcia, Gothamist reported.

But just hours later, the board tweeted that it had become aware of a "discrepancy" in the ranked-choice voting results and pulled them from its website.

In a follow-up apology, the board acknowledged that it had erroneously left 135,000 test votes in its election system, producing "additional records" that likely impacted an accurate tally.

"At this point it really seems like an issue of human error," WNYC reporter Brigid Bergin told NPR's Morning Edition.

"The board does conduct a lot of pre-election testing to make sure their systems are working and, obviously, that was even more important this time, because it was the first time they were using this new ranked-choice voting system," she added.

Bergin said the board is expected to release a corrected ranked-choice voting report Wednesday, but it will still be preliminary and it won't include 124,000 absentee ballots.

How the candidates are reacting

All of the mayoral contenders expressed frustration with the board's blunder.

"Today's mistake by the Board of Elections was unfortunate," Adams tweeted Tuesday. "It is critical that New Yorkers are confident in their electoral system, especially as we rank votes in a citywide election for the first time."

Garcia, who was fleetingly thrust into second place by the incorrect ranked-choice voting report, called for a more thorough accounting of what went wrong.

"The Board of Elections' release of incorrect ranked choice votes is deeply troubling and requires a much more transparent and complete explanation. Every ranked choice and absentee vote must be counted accurately so that all New Yorkers have faith in our democracy and our government," she tweeted.

Progressive candidate Maya Wiley said this week's misstep was just the latest in a string of mistakes by the board.

"This error by the Board of Elections is not just failure to count votes properly today, it is the result of generations of failures that have gone unaddressed," Wiley said. "Today, we have once again seen the mismanagement that has resulted in a lack of confidence in results, not because there is a flaw in our election laws, but because those who implement it have failed too many times."

WNYC's Bergin said she thought the misstep would not cause voters to question the election results but that it may diminish the board's reputation in the eyes of the public.

"This agency is really the last bastion of true patronage politics in New York," she said. "There's been a push to overhaul the agency, to give the staff more authority over political appointees. But ultimately that's all up to state lawmakers to do."

This content is from Southern California Public Radio. View the original story at SCPR.org.

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Machine learning algorithms can sometimes do a great job with a little help from human expertise, at least in the field of materials science. In many specialized areas of science, engineering and medicine, researchers are turning to machine learning algorithms to analyze data sets that have grown too large for humans to understand. In materials science, success with this effort could accelerate the design of next-generation advanced functional materials, where development now usually depends on old-fashioned trial and error. By themselves, however, data analytics techniques borrowed from other research areas often fail to provide the insights needed to help materials scientists and engineers choose which of many variables to adjust -- and the techniques can't account for dramatic changes such as the introduction of a new chemical compound into the process. In a new study, researchers explain a technique known as dimensional stacking, which shows that human experience still has a role to play in the age of machine intelligence. The machines gain an edge at solving a challenge when the data to be analyzed are intelligently organized based on human knowledge of what factors are likely to be important and related. "When your machine accepts strings of data, it really does matter how you are putting those strings together," said Nazanin Bassiri-Gharb, the paper's corresponding author and a scientist at the Georgia Institute of Technology. "We must be mindful that the organization of data before it goes to the algorithm makes a difference. If you don't plug the information in correctly, you will get a result that isn't necessarily correlated with the reality of the physics and chemistry that govern the materials."

Image credit: Rob Felt/Georgia Tech

Many business users have approached generative AI technology more cautiously because it can make up untrue facts and be tricked into saying unsettling things. Oracle's human resources software is used by big businesses for hiring new employees and providing performance evaluations, among other things. Oracle will put a button on many of the fields in the software that will automatically generate draft text for things like job listings or performance goals.

Cynthia Eades, a long-time resident of Catawba County who is currently serving as Human Resources Director in Iredell County and has ten years of experience in local government human resources, has been named Catawba County�s new Human Resources Director. She will begin her new duties with Catawba County on July 1, 2010.

Cancer-causing chemicals that occur naturally in foods are far more numerous in the human diet than synthetic carcinogens, yet both types are consumed at levels so low that they currently appear to pose little threat to human health, a committee of the National Research Council said in a report released today.

The United States should ban human reproductive cloning aimed at creating a child.

As part of the $4 billion settlement announced today between the federal government and BP concerning the 2010 Deepwater Horizon disaster, the National Academy of Sciences has been asked to establish a new $350 million, 30-year program on human health and environmental protection in the Gulf of Mexico.

A new report from the National Research Council has upheld the listing of styrene as “reasonably anticipated to be a human carcinogen” in the National Toxicology Program’s 12th Report on Carcinogens (RoC).

A new report from the National Research Council has upheld the listing of formaldehyde as “known to be a human carcinogen” in the National Toxicology Program 12th Report on Carcinogens (RoC).

The National Academy of Sciences and the National Academy of Medicine are launching a major initiative to guide decision making about controversial new research involving human gene editing.

During the National Academy of Medicine (NAM) Annual Meeting, Leonard Rubenstein, Director of the Program on Human Rights, Health and Conflict (Center for Public Health and Human Rights) at Johns Hopkins Bloomberg School of Public Health, and Dr. Denis Mukwege, founder and medical director of Panzi Hospital in the DRC, spoke to NAM members about attacks against healthcare professionals globally and the importance of supporting the work of medical professionals in conflict zones.

Scientific advances in molecular biology over the past 50 years have produced remarkable progress in medicine. Some of these advances have also raised important ethical and societal issues – for example, about the use of recombinant DNA technologies or embryonic stem cells.

We thank the organizers of our International Summit on Human Gene Editing for their thoughtful concluding statement and welcome their call for us to continue to lead a global discussion on issues related to human gene editing.

Infectious disease outbreaks that turn into epidemics or pandemics can kill millions of people and cause trillions of dollars of damage to economic activity, says a new report from the international, independent Commission on a Global Health Risk Framework for the Future.