git Alcohol Abuse Agitated by COVID-19 Stirring Liver Concerns By www.webmd.com Published On :: Thu, 07 May 2020 10:35:22 EST Hospitals are seeing an increase in admissions related to alcohol abuse as recovery centers are shutting down and people are drinking more during the pandemic. Full Article
git Evaluation of an Automated Digital Scoring System of Dental Plaque By jdh.adha.org Published On :: 2020-04-30T12:39:03-07:00 Purpose: Measurement of dental plaque is frequently used as an indicator of overall oral health. The purpose of this study was to compare a manual (visual) plaque scoring system (University of Mississippi Oral Hygiene Index, UM-OHI) with an innovative automated digital scoring system.Methods: Mechanically ventilated, intensive care unit (ICU) patients (n=79) were the study population. Informed consent was given by the subject's legally authorized representative. Digital images of dental plaque were taken using an intraoral camera; and the quantity of dental plaque was scored using the UM-OHI and with a digitized automated scoring system. Distributions of dental plaque scores from both methods were plotted. Pearson correlation coefficients and intra-class coefficients were calculated between the two methods.Results: Participant mean age was 57.3 years; respiratory failure was the most prevalent admission diagnosis (55.7%). The mean percentage of dental plaque calculated by the manual method was found to be remarkably higher (67.3% ± 18.7%) than the percentage of dental plaque calculated by the automated scoring method (23.7% ± 15.2%) (p<0.0001). Despite remarkably different distributions of plaque scores, both the automated and manual scoring systems demostrated relatively high correlation (r=0.62) and good reliability (ICC=0.63).Conclusion: The automated digital scoring system resulted in a significantly lower overall percentage of total dental plaque as compared to the UM-OHI manual scoring system. While the automated digital scoring system may be more precise than a manual (visual) scoring system, its use should be weighed against the added effort, cost, and expertise required for the method. Further study is needed to determine whether an automated digital scoring system can be commercialized and is warranted for use outside of research settings. Full Article
git Putative {beta}-Barrel Outer Membrane Proteins of the Bovine Digital Dermatitis-Associated Treponemes: Identification, Functional Characterization, and Immunogenicity [Microbial Immunity and Vaccines] By iai.asm.org Published On :: 2020-04-20T08:00:38-07:00 Bovine digital dermatitis (BDD), an infectious disease of the bovine foot with a predominant treponemal etiology, is a leading cause of lameness in dairy and beef herds worldwide. BDD is poorly responsive to antimicrobial therapy and exhibits a relapsing clinical course; an effective vaccine is therefore urgently sought. Using a reverse vaccinology approach, the present study surveyed the genomes of the three BDD-associated Treponema phylogroups for putative β-barrel outer membrane proteins and considered their potential as vaccine candidates. Selection criteria included the presence of a signal peptidase I cleavage site, a predicted β-barrel fold, and cross-phylogroup homology. Four candidate genes were overexpressed in Escherichia coli BL21(DE3), refolded, and purified. Consistent with their classification as β-barrel OMPs, circular-dichroism spectroscopy revealed the adoption of a predominantly β-sheet secondary structure. These recombinant proteins, when screened for their ability to adhere to immobilized extracellular matrix (ECM) components, exhibited a diverse range of ligand specificities. All four proteins specifically and dose dependently adhered to bovine fibrinogen. One recombinant protein was identified as a candidate diagnostic antigen (disease specificity, 75%). Finally, when adjuvanted with aluminum hydroxide and administered to BDD-naive calves using a prime-boost vaccination protocol, these proteins were immunogenic, eliciting specific IgG antibodies. In summary, we present the description of four putative treponemal β-barrel OMPs that exhibit the characteristics of multispecific adhesins. The observed interactions with fibrinogen may be critical to host colonization and it is hypothesized that vaccination-induced antibody blockade of these interactions will impede treponemal virulence and thus be of therapeutic value. Full Article
git Family Medicine Certification Longitudinal Assessment after One Year By www.jabfm.org Published On :: 2020-03-16T09:31:37-07:00 Full Article
git Multicenter Evaluation of a PCR-Based Digital Microfluidics and Electrochemical Detection System for the Rapid Identification of 15 Fungal Pathogens Directly from Positive Blood Cultures [Mycology] By jcm.asm.org Published On :: 2020-04-23T08:00:29-07:00 Routine identification of fungal pathogens from positive blood cultures by culture-based methods can be time-consuming, delaying treatment with appropriate antifungal agents. The GenMark Dx ePlex investigational use only blood culture identification fungal pathogen panel (BCID-FP) rapidly detects 15 fungal targets simultaneously in blood culture samples positive for fungi by Gram staining. We aimed to determine the performance of the BCID-FP in a multicenter clinical study. Blood culture samples collected at 10 United States sites and tested with BCID-FP at 4 sites were compared to the standard-of-care microbiological and biochemical techniques, fluorescence in situ hybridization using peptide nucleic acid probes (PNA-FISH) and matrix-assisted laser desorption ionization–time of flight mass spectrometry (MALDI-TOF MS). Discrepant results were analyzed by bi-directional PCR/sequencing of residual blood culture samples. A total of 866 clinical samples, 120 retrospectively and 21 prospectively collected, along with 725 contrived samples were evaluated. Sensitivity and specificity of detection of Candida species (C. albicans, C. auris, C. dubliniensis, C. famata, C. glabrata, C. guilliermondii, C. kefyr, C. krusei, C. lusitaniae, C. parapsilosis, and C. tropicalis) ranged from 97.1 to 100% and 99.8 to 100%, respectively. For the other organism targets, sensitivity and specificity were as follows: 100% each for Cryptococcus neoformans and C. gattii, 98.6% and 100% for Fusarium spp., and 96.2% and 99.9% for Rhodotorula spp., respectively. In 4 of the 141 clinical samples, the BCID-FP panel correctly identified an additional Candida species, undetected by standard-of-care methods. The BCID-FP panel offers a faster turnaround time for identification of fungal pathogens in positive blood cultures that may allow for earlier antifungal interventions and includes C. auris, a highly multidrug-resistant fungus. Full Article
git Image Quality and Activity Optimization in Oncologic 18F-FDG PET Using the Digital Biograph Vision PET/CT System By jnm.snmjournals.org Published On :: 2020-05-01T06:31:37-07:00 The first Biograph Vision PET/CT system (Siemens Healthineers) was installed at the University Medical Center Groningen. Improved performance of this system could allow for a reduction in activity administration or scan duration. This study evaluated the effects of reduced scan duration in oncologic 18F-FDG PET imaging on quantitative and subjective imaging parameters and its influence on clinical image interpretation. Methods: Patients referred for a clinical PET/CT scan were enrolled in this study, received a weight-based 18F-FDG injected activity, and underwent list-mode PET acquisition at 180 s per bed position (s/bp). Acquired PET data were reconstructed using the vendor-recommended clinical reconstruction protocol (hereafter referred to as "clinical"), using the clinical protocol with additional 2-mm gaussian filtering (hereafter referred to as "clinical+G2"), and—in conformance with European Association of Nuclear Medicine Research Ltd. (EARL) specifications—using different scan durations per bed position (180, 120, 60, 30, and 10 s). Reconstructed images were quantitatively assessed for comparison of SUVs and noise. In addition, clinically reconstructed images were qualitatively evaluated by 3 nuclear medicine physicians. Results: In total, 30 oncologic patients (22 men, 8 women; age: 48–88 y [range], 67 ± 9.6 y [mean ± SD]) received a single weight-based (3 MBq/kg) 18F-FDG injected activity (weight: 45–123 kg [range], 81 ± 15 kg [mean ± SD]; activity: 135–380 MBq [range], 241 ± 47.3 MBq [mean ± SD]). Significant differences in lesion SUVmax were found between the 180-s/bp images and the 30- and 10-s/bp images reconstructed using the clinical protocols, whereas no differences were found in lesion SUVpeak. EARL-compliant images did not show differences in lesion SUVmax or SUVpeak between scan durations. Quantitative parameters showed minimal deviation (~5%) in the 60-s/bp images. Therefore, further subjective image quality assessment was conducted using the 60-s/bp images. Qualitative assessment revealed the influence of personal preference on physicians’ willingness to adopt the 60-s/bp images in clinical practice. Although quantitative PET parameters differed minimally, an increase in noise was observed. Conclusion: With the Biograph Vision PET/CT system for oncologic 18F-FDG imaging, scan duration or activity administration could be reduced by a factor of 3 or more with the use of the clinical+G2 or the EARL-compliant reconstruction protocol. Full Article
git High cytomegalovirus serology and subsequent COPD-related mortality: a longitudinal study By openres.ersjournals.com Published On :: 2020-04-27T00:30:10-07:00 Background Positive serology for cytomegalovirus (CMV) has been associated with all-cause mortality risk but its role in COPD mortality is unknown. The objective of the present study was to assess the relationship between CMV serology and COPD mortality. Methods We analysed data from 806 participants in the Tucson Epidemiological Study of Airway Obstructive Disease who, at enrolment, were aged 28–70 years and had completed lung function tests. We tested CMV serology in sera from enrolment and defined "high CMV serology" as being in the highest tertile. Vital status, date and cause of death were assessed through death certificates and/or linkage with the National Death Index up to January 2017. The association of CMV serology with all-cause and cause-specific mortality risk was tested in Cox models adjusted for age, sex, level of education, body mass index, smoking status and pack-years. Results High CMV serology was marginally associated with all-cause mortality (p=0.071) but the effect was inversely dependent on age, with the association being much stronger among participants <55 years than among participants ≥55 years at enrolment (p-value for CMV-by-age interaction <0.001). Compared with low CMV serology, high CMV serology was associated with mortality from COPD among all subjects (adjusted hazard ratio (HR) 2.38, 95% CI 1.11–5.08; p=0.025) and particularly in subjects <55 years old at enrolment (HR 5.40, 95% CI 1.73–16.9; p=0.004). Consistent with these results, high CMV serology also predicted mortality risk among subjects who already had airflow limitation at enrolment (HR 2.10, 95% CI 1.20–3.68; p=0.009). Conclusions We report a strong relationship between CMV serology and the risk of dying from COPD, and thus identify a novel risk factor for COPD mortality. Full Article
git Microencapsulated G3C Hybridoma Cell Graft Delays the Onset of Spontaneous Diabetes in NOD Mice by an Expansion of Gitr+ Treg Cells By diabetes.diabetesjournals.org Published On :: 2020-04-20T12:00:34-07:00 As an alternative to lifelong insulin supplementation, potentiation of immune tolerance in patients with type 1 diabetes could prevent the autoimmune destruction of pancreatic islet β-cells. This study was aimed to assess whether the G3c monoclonal antibody (mAb), which triggers the glucocorticoid-induced TNFR-related (Gitr) costimulatory receptor, promotes the expansion of regulatory T cells (Tregs) in SV129 (wild-type) and diabetic-prone NOD mice. The delivery of the G3c mAb via G3C hybridoma cells enveloped in alginate-based microcapsules (G3C/cps) for 3 weeks induced Foxp3+ Treg-cell expansion in the spleen of wild-type mice but not in Gitr–/– mice. G3C/cps also induced the expansion of nonconventional Cd4+Cd25–/lowFoxp3lowGitrint/high (GITR single-positive [sp]) Tregs. Both Cd4+Cd25+GitrhighFoxp3+ and GITRsp Tregs (including also antigen-specific cells) were expanded in the spleen and pancreas of G3C/cps-treated NOD mice, and the number of intact islets was higher in G3C/cps-treated than in empty cps-treated and untreated animals. Consequently, all but two G3C/cps-treated mice did not develop diabetes and all but one survived until the end of the 24-week study. In conclusion, long-term Gitr triggering induces Treg expansion, thereby delaying/preventing diabetes development in NOD mice. This therapeutic approach may have promising clinical potential for the treatment of inflammatory and autoimmune diseases. Full Article
git Digital medical photography recording: a personal view By bjgp.org Published On :: 2020-04-30T16:04:41-07:00 Full Article
git Body Surface Examination Facilitated by Digital Microscopy [Innovations in Primary Care] By www.annfammed.org Published On :: 2020-03-09T14:00:11-07:00 Full Article
git GITR Agonism Triggers Antitumor Immune Responses through IL21-Expressing Follicular Helper T Cells By cancerimmunolres.aacrjournals.org Published On :: 2020-05-01T00:05:25-07:00 Although treatment with the glucocorticoid-induced tumor necrosis factor receptor–related protein (GITR) agonistic antibody (DTA-1) has shown antitumor activity in various tumor models, the underlying mechanism is not fully understood. Here, we demonstrate that interleukin (IL)-21–producing follicular helper T (Tfh) cells play a crucial role in DTA-1–induced tumor inhibition. The administration of DTA-1 increased IL21 expression by Tfh cells in an antigen-specific manner, and this activation led to enhanced antitumor cytotoxic T lymphocyte (CTL) activity. Mice treated with an antibody that neutralizes the IL21 receptor exhibited decreased antitumor activity when treated with DTA-1. Tumor growth inhibition by DTA-1 was abrogated in Bcl6fl/flCd4Cre mice, which are genetically deficient in Tfh cells. IL4 was required for optimal induction of IL21-expressing Tfh cells by GITR costimulation, and c-Maf mediated this pathway. Thus, our findings identify GITR costimulation as an inducer of IL21-expressing Tfh cells and provide a mechanism for the antitumor activity of GITR agonism. Full Article
git Intratumoral Delivery of a PD-1-Blocking scFv Encoded in Oncolytic HSV-1 Promotes Antitumor Immunity and Synergizes with TIGIT Blockade By cancerimmunolres.aacrjournals.org Published On :: 2020-05-01T00:05:25-07:00 Oncolytic virotherapy can lead to systemic antitumor immunity, but the therapeutic potential of oncolytic viruses in humans is limited due to their insufficient ability to overcome the immunosuppressive tumor microenvironment (TME). Here, we showed that locoregional oncolytic virotherapy upregulated the expression of PD-L1 in the TME, which was mediated by virus-induced type I and type II IFNs. To explore PD-1/PD-L1 signaling as a direct target in tumor tissue, we developed a novel immunotherapeutic herpes simplex virus (HSV), OVH-aMPD-1, that expressed a single-chain variable fragment (scFv) against PD-1 (aMPD-1 scFv). The virus was designed to locally deliver aMPD-1 scFv in the TME to achieve enhanced antitumor effects. This virus effectively modified the TME by releasing damage-associated molecular patterns, promoting antigen cross-presentation by dendritic cells, and enhancing the infiltration of activated T cells; these alterations resulted in antitumor T-cell activity that led to reduced tumor burdens in a liver cancer model. Compared with OVH, OVH-aMPD-1 promoted the infiltration of myeloid-derived suppressor cells (MDSC), resulting in significantly higher percentages of CD155+ granulocytic-MDSCs (G-MDSC) and monocytic-MDSCs (M-MDSC) in tumors. In combination with TIGIT blockade, this virus enhanced tumor-specific immune responses in mice with implanted subcutaneous tumors or invasive tumors. These findings highlighted that intratumoral immunomodulation with an OV expressing aMPD-1 scFv could be an effective stand-alone strategy to treat cancers or drive maximal efficacy of a combination therapy with other immune checkpoint inhibitors. Full Article
git Diabetes-induced eye disease among First Nations people in Ontario: a longitudinal, population-based cohort study By www.cmajopen.ca Published On :: 2020-04-17T08:42:26-07:00 Background: In Canada, First Nations populations experience a higher incidence of diabetes and diabetes-related complications than other people. Given the paucity of information on use of preventive eye examinations and the need for interventional care for severe retinopathy among First Nations people, we carried out a population-based study to compare rates of eye examinations and interventional therapies to treat vision-threatening stages of diabetic retinopathy among First Nations people and other people with diabetes in Ontario. Methods: In collaboration with the Chiefs of Ontario, we carried out a population-based study to identify cohorts of First Nations people and other people with diabetes in Ontario from 1995/96 to 2014/15. We used linked health administrative databases to evaluate rates of eye examination (2005/06–2014/15) and severe diabetic retinopathy treatment and compared them between the 2 populations, and between First Nations people living in and outside of First Nations communities. Results: We identified 23 013 First Nations people and 1 364 222 other people diagnosed with diabetes from 1995/96 to 2014/15, of whom 49.8% (95% confidence interval [CI] 48.9%–50.7%) and 53.8% (95% CI 53.7%–54.0%), respectively, received an eye examination in 2014/15. Eye examination rates were similar for First Nations people regardless of whether they lived in or outside a First Nations community. First Nations people developed severe diabetic retinopathy at a faster rate than other people (hazard ratio 1.19, 95% CI 1.02–1.38). The gap between First Nations people and other people in the proportion requiring therapy for severe diabetic retinopathy was especially prominent among younger people. There were no significant differences in rates of diabetic retinopathy treatment in First Nations people stratified by place of residence. Interpretation: Eye examination rates remain suboptimal among people with diabetes in Ontario and were lower among First Nations people. This is particularly concerning in light of our other findings showing an increased risk of requiring treatment for advanced diabetic retinopathy and the accelerated rate of diabetic retinopathy progression among First Nations people with diabetes. Full Article
git Assessment of Apparent Internal Carotid Tandem Occlusion on High-Resolution Vessel Wall Imaging: Comparison with Digital Subtraction Angiography [EXTRACRANIAL VASCULAR] By www.ajnr.org Published On :: 2020-04-09T06:30:48-07:00 BACKGROUND AND PURPOSE: Not all tandem occlusions diagnosed on traditional vascular imaging modalities, such as MRA, represent actual complete ICA occlusion. This study aimed to explore the utility of high-resolution vessel wall imaging in identifying true ICA tandem occlusions and screening patients for their suitability for endovascular recanalization. MATERIALS AND METHODS: Patients with no signal in the ICA on MRA were retrospectively reviewed. Two neuroradiologists independently reviewed their high-resolution vessel wall images to assess whether there were true tandem occlusions and categorized all cases into intracranial ICA occlusion, extracranial ICA occlusion, tandem occlusion, or near-occlusion. DSA classified patient images into the same 4 categories, which were used as the comparison with high-resolution vessel wall imaging. The suitability for recanalization of occluded vessels was evaluated on high-resolution vessel wall imaging compared with DSA. RESULTS: Forty-five patients with no ICA signal on MRA who had available high-resolution vessel wall imaging and DSA images were included. Among the 34 patients (34/45, 75.6%) with tandem occlusions on DSA, 18 cases also showed tandem occlusions on high-resolution vessel wall imaging. The remaining 16 patients, intracranial ICA, extracranial ICA occlusions and near-occlusions were found in 2, 6, and 8 patients, respectively, on the basis of high-resolution vessel wall imaging. A total of 20 cases (20/45, 44.4%) were considered suitable for recanalization on the basis of both DSA and high-resolution vessel wall imaging. Among the 25 patients deemed unsuitable for recanalization by DSA, 11 were deemed suitable for recanalization by high-resolution vessel wall imaging. CONCLUSIONS: High-resolution vessel wall imaging could allow identification of true ICA tandem occlusion in patients with an absence of signal on MRA. Findings on high-resolution vessel wall imaging can be used to screen more suitable candidates for recanalization therapy. Full Article
git Digital storytelling: Selling properties with ease in a hyper-connected world By batdongsan.com.vn Published On :: 17:34 04/03/2020 Three marketing experts share their unconventional means of capturing the attention of potential homeowners of today. Full Article
git 6 guiding parameters to upgrade your workplace environment in the digital economy By batdongsan.com.vn Published On :: 11:15 05/05/2020 Prof. Jason Pomeroy talks about the rise of the digital economy and its impact on the workplace. Full Article
git Podcast 37: How to Pivot to Digital Education – With Ashish Rangnekar By feedproxy.google.com Published On :: Sat, 09 May 2020 08:36:04 +0000 WELCOME TO EPISODE 37 OF THE TALENTED LEARNING SHOW! Learn how trade associations and training companies are now pivoting to total digital education due to […] The post Podcast 37: How to Pivot to Digital Education – With Ashish Rangnekar appeared first on e-Learning Feeds. Full Article eLearning Software adaptive learning association learning Buying LMS competency confidence continuing education Digital Education Extended Enterprise Learning Content Learning Management learning management systems LMS microlearning online certification Talented Learning Show Podcast trade association Training Business
git Sophie Marschner turns real-world data into a digital topography in Monolith By www.factmag.com Published On :: Thu, 07 May 2020 11:00:00 +0000 Generative visuals and eerie sound design based on height maps of glaciers, canyons and estuaries. London-based motion graphic designer Sophie Marschner transforms real-world data into a delicate digital topography in Monolith. By using the height maps of various large-scale landmarks, including glaciers, canyons and estuaries, Marschner maps the outside world into a more intimate, digital […] The post Sophie Marschner turns real-world data into a digital topography in Monolith appeared first on FACT Magazine. Full Article Series Audiovisual Featured Stories Featured Top sticky1 Sophie Marschner Scotch Mist
git Agility Robotics Unveils Upgraded Digit Walking Robot By feedproxy.google.com Published On :: Mon, 14 Oct 2019 15:59:00 GMT The improvements include nimbler feet, better perception, and fully custom electronics Full Article robotics robotics/humanoids
git RPGCast – Episode 342: “It’s Not Available Digitally” By feedproxy.google.com Published On :: Sun, 22 Mar 2015 05:18:23 +0000 Final Fantasy XI announces its plans for its golden years. Fossil Fighters still exists. Then Phil either recommends or doesn’t recommend Avernum. I’m still not... Full Article News Podcasts RPG Cast
git RPGCast – Episode 497: “Git Gud Or Git A Refund” By feedproxy.google.com Published On :: Sat, 23 Mar 2019 18:40:06 +0000 A slightly smaller show doesn’t mean any less action, news, or hilariously questionable jibes for this week’s RPGCast. We learn we cannot, in fact, git... Full Article News Podcasts RPG Cast Chocobo's Mystery Dungeon: Every Buddy! Dragon Quest Builders Final Fantasy IX Final Fantasy XIV Minit Record of Agarest War: Mariage The Witcher 2
git Gilgit to Guwahati: Why Doordarshan’s new weather forecast will up temperatures in Pakistan By in.news.yahoo.com Published On :: Sat, 09 May 2020 01:46:51 -0500 New Delhi, May 08: From Gilgit to Guwahati, Doordarshan and All India Radio have started forecasting the weather from across the territory of India. These Weather reports cover every small detail from every nook and corner of the country while highlighting Full Article
git Eight Digital Education Resources From Around the Smithsonian By www.smithsonianmag.com Published On :: Tue, 17 Mar 2020 14:27:59 +0000 The newly launched #SmithsonianEdu campaign highlights 1.7 million online tools geared specifically toward students and teachers Full Article
git LIVE NOW: Watch the Smithsonian's Earth Optimism Digital Summit By www.smithsonianmag.com Published On :: Thu, 23 Apr 2020 13:34:12 +0000 The two-day virtual event will bring scientists and many other experts to highlight success stories in conservation Full Article
git Men's Milan Fashion Week slips to July in digital-only format due to coronavirus By feeds.reuters.com Published On :: Wed, 06 May 2020 13:18:12 -0400 The Men's Milan Fashion Week set for June will be postponed to mid-July and presented in purely digital format with photos and video to avoid the risk of coronavirus contagion, Italy's national fashion chamber said on Wednesday. Full Article entertainmentNews
git Free $15 Target GiftCard with $100 iTunes Digital Gift Card purchase at Target By www.cheapassgamer.com Published On :: Thu, 07 May 2020 14:25:35 +0000 Different digital styles to choose from! Online only. http://goto.target.com/itunesgiftcards --> Full Article
git Review: Sagrada, a top dice-drafting board game, goes digital By arstechnica.com Published On :: Sat, 02 May 2020 12:30:35 +0000 Get yer glass on with this great version of the board game hit. Full Article Gaming & Culture ars cardboard Board games sagrada
git Digital-friendly recession: How Big Tech got even bigger in the midst of a market meltdown By business.financialpost.com Published On :: Wed, 06 May 2020 17:09:17 +0000 Many analysts expected the stocks to fall back to earth when the next downturn came Full Article Innovation Investing
git Pubs pivot to digital: 'We hope that people feel that the world outside is still there' By www.theguardian.com Published On :: 2020-05-07T17:30:05Z Weekly meat tray giveaways, craft beer deliveries and trivia held over Zoom. As pubs stand empty, those that run them look to the internetAcross Australia, pubs stand empty because of the Covid-19 lockdowns. Some venues have shut entirely, others have pivoted to takeaway businesses, and the majority have had to make changes to their staffing.While the future of physical pubs remains very uncertain for the coming months, the entertainers, brewers and chefs that rely on pubs for their livelihood are finding ways to recreate pub experiences in patrons’ homes. Continue reading... Full Article Pubs Restaurants Coronavirus outbreak Australia news Food Australian food and drink Australian lifestyle Business
git Deliveroo is giving couples the chance to win a £1,500 wedding breakfast for digital lockdown nuptials By www.standard.co.uk Published On :: 2020-04-17T09:01:52Z Has your wedding been affected by coronavirus? Deliveroo wants to help Full Article
git Gwyneth Paltrow to replace her £1,000-a-ticket Goop Summit with free digital 'In Goop Health' sessions By www.standard.co.uk Published On :: 2020-04-20T08:58:35Z Paltrow's pricey wellness summit just got mighty accessible Full Article
git London Fashion Week will be digital-only for first time By www.standard.co.uk Published On :: 2020-04-21T07:11:00Z As both menswear and womenswear combine for the digital event, could this spell the end for runway shows permanently? Full Article
git Apple confirms WWDC 2020 date as annual conference goes digital By www.standard.co.uk Published On :: 2020-05-05T14:06:06Z Mark June 22 in your calendars now Full Article
git Hay Festival unveils its first-ever digital programme By www.standard.co.uk Published On :: 2020-05-05T16:01:05Z This year's digital-only festival has dropped nearly 600 events, but it will be completely free Full Article
git Digital game sales data just got a little less opaque By arstechnica.com Published On :: Mon, 11 Jul 2016 04:01:48 +0000 Major publishers working with NPD to share their download numbers. Full Article Gaming & Culture business digital game NPD publishers Sales data
git We’ve been missing a big part of game industry’s digital revolution By arstechnica.com Published On :: Sat, 22 Apr 2017 13:00:45 +0000 NPD “restatement” shows consistent spending growth as digital sales dominate. Full Article Gaming & Culture business ESA gaming NPD revenue
git New remote medical norms land in San Francisco digital health firm's wheelhouse By feeds.bizjournals.com Published On :: Fri, 08 May 2020 21:39:59 +0000 Omada Health founder and CEO Sean Duffy had an a-ha moment about digital health when he saw his mother start asking her doctor for FaceTime appointments. “That’s when I realized we are in a different world right now,” he said. Full Article
git Developers join call for GitHub to cancel its ICE contract By www.latimes.com Published On :: Wed, 4 Dec 2019 10:43:10 -0500 Open source developers, GitHub's power users, are joining the software platform's employees in calling for the company to cancel its contract with ICE. A boycott could be next. Full Article
git New stamps, digital project mark centenary of Group of Seven's debut By www.cbc.ca Published On :: Thu, 7 May 2020 13:58:48 EDT On the 100th anniversary of the Group of Seven's inaugural exhibit, the influential art collective is being recognized with efforts putting their distinctively Canadian paintings in front of a fresh crop of art lovers. Full Article News/Entertainment
git Using digital twins to design more sustainable cities By www.eurekalert.org Published On :: Thu, 07 May 2020 00:00:00 EDT Over the past several years, a collaboration at HLRS has been developing a digital twin of Herrenberg, a small city just outside of Stuttgart, Germany. The Herrenberg study has already provided valuable information for city planners and government officials in the state of Baden-Württemberg, and paves the way for improving the model to include additional kinds of data. Full Article
git GE’s Digital Spinoff: What Does It Mean for the Internet of Things? By sandhill.com Published On :: Thu, 23 Aug 2018 00:00:00 +0000 Reports claim General Electric is selling off key digital assets, which likely include its Predix platform. What are the implications for IoT? Keep on reading: GE’s Digital Spinoff: What Does It Mean for the Internet of Things? Full Article
git How I survived my two-week digital diet By www.thestar.com Published On :: Fri, 13 Nov 2015 11:00:00 EST No Smartphone. No Google. No Twitter. No texting and no music — except for a Walkman. Full Article
git Salesforce Acquires Krux Digital for $750,000,000 By www.sandhill.com Published On :: Wed, 05 Oct 2016 07:00:04 +0000 Krux Digital helps anyone with a website safeguard, manage, and make responsible use of consumer data signatures across devices, sources, and formats. Krux arms web publishers with the technology and know-how to compete in a data game currently dominated by advertisers and market middlemen. Full Article
git Join Us Online May 13 for Xcelerating Life Sciences: Biopharma’s Future in Digital Health By xconomy.com Published On :: Thu, 07 May 2020 13:15:48 +0000 Learn how digital tech is accelerating medical breakthroughs by registering your team to attend Xcelerating Life Sciences Boston: Biopharma’s Future in Digital Health. While some content focuses on the Boston ecosystem, we’re confident the forum – and virtual networking – will be valuable to a national audience. The May 13, 2020 event will explore the […] Full Article Boston Boston blog main Boston top stories National National blog main National top stories Biotech event Life Science Life Sciences
git Dr Wajid Hussain appointed new clinical director for digital health at RCP By www.pharmafile.com Published On :: Fri, 02 Aug 2019 11:20:05 +0000 The Royal College of Physicians (RCP) has appointed Dr Wajid Hussain as its new clinical director for digital health. Dr Hussain, a cardiologist and cardiac electrophysicist at the Royal Brompton and Harefield NHS Trust, has a demonstrated interest in IT and health. While he currently represents the views of clinicians on the Trust’s IT committee, Dr Hussain completed a Diploma in Digital Health Leadership at the NHS Digital Academy last year. He is also currently studying for a Master’s in Digital Health leadership at Imperial College London. read more Full Article digital health IT pharma RCP Research and Development Royal College of Physicians Medical Communications Sales and Marketing Business Services Manufacturing and Production
git Novartis acquires digital therapeutics specialist Amblyotech By www.outsourcing-pharma.com Published On :: Tue, 28 Apr 2020 15:39:00 +0100 The pharmaceutical firm has purchased the company, which specializes in advancing treatments and diagnostics for ocular disorders. Full Article Markets & Regulations
git EU efforts turn towards digital for 2019 By www.acrohealth.org Published On :: Wed, 27 Feb 2019 23:46:11 +0000 2018 was a busy and productive year for ACRO’s European Scientific & Regulatory Committee, which meets quarterly in London. While the Committee focused largely on the continuing implementation of the EU Clinical Trial Regulation, there were also opportunities to engage with regulators on other topics ranging from European regulatory strategy to Advanced Therapies to the urgent challenges of Brexit. Full Article News Clinical Trial Regulation digital EU
git ACRO expands membership with addition of three digital technology companies By www.acrohealth.org Published On :: Mon, 15 Apr 2019 15:54:16 +0000 The Association of Clinical Research Organizations (ACRO) is pleased to announce the expansion of its membership to include ERT, Oracle and Veeva. These new ACRO member companies, with their focus on digital technologies that enable global clinical trials, characterize the ongoing innovation and evolution of contemporary clinical research. ACRO now has 12 member companies. Full Article News Press Releases ERT IQVIA membership Oracle Veeva
git International Criminal Figure Pleads Guilty to $138 Million Fuel Tax Scheme After Nearly 13 Years as a Fugitive By www.justice.gov Published On :: Fri, 27 Feb 2009 15:02:50 EST After nearly 13 years as a fugitive, a former New Jersey resident has been returned to the United States, and pleaded guilty today to conspiring to committing one of the nations largest known motor fuel excise tax schemes. Aaron Misulovin a/k/a Albert Friedman, a/k/a Valery Vibornov, pleaded guilty before U.S. District Judge Joseph E. Irenas in Camden, N.J., to one count of conspiracy, three counts of wire fraud, three counts of money laundering and three counts of tax evasion. Full Article OPA Press Releases
git Leader of Colombian Drug Cartel and Former FBI Top-Ten Fugitive Pleads Guilty to Drug, Murder and Racketeering Charges By www.justice.gov Published On :: Tue, 11 Aug 2009 13:46:20 EDT Diego Montoya Sanchez, 48, one of the leaders of the Norte Valle Colombian drug cartel and a former FBI Top Ten Fugitive, pleaded guilty today in Miami to drug trafficking, murder and racketeering charges. Full Article OPA Press Releases
