The subject matter of the present disclosure is directed to developing a method of measuring the amount of producible oil and the producible oil saturation in shale-oil reservoirs using sample source rock. Further, the physical and chemical properties and amounts of producible oil in shale-oil reservoir samples may be determined. First and second solvents are applied to a sample source rock to extract petroleum from the sample source rock. The extracted source rock, the twice-extracted source rock, and the first and second extracted petroleum may be analyzed to determine the characteristics and properties of the reservoir rock.

A method of operating the automated sample workcell for processing one or more biological samples is presented. The method comprises receiving one or more biological samples. Each biological sample is contained in a sample tube. Each sample tube is a tube type. If a test order was received for at least one of the biological samples, the test order being indicative of one or more first processing steps, the workcell can automatically execute the one or more first processing steps. If the test order was not received, one or more second processing steps can be determined based on the tube type of the sample tube that contains the at least one biological sample and the one or more second processing steps can then be executed.

A method and apparatus for dating a body sample, such as blood, includes taking at least one spectroscopic measurement of the sample at at least two predetermined positions in the spectrum having spectral characteristics corresponding to at least two predetermined substances present in the sample that have a time varying relationship with each other. A measured relative concentration of each of the predetermined substances is then determined from the measurement, and the measured relative concentrations of the two predetermined substances is compared with a known variation of the relative concentrations of the two predetermined substances over time. A good fit of the measured relative concentrations to the known variation of the relative concentrations is then determined, so as to provide an indication of the age of the sample. Alternatively, instead of measuring the relative concentrations of each of the predetermined substances, the rate of change of the relative concentrations is determined.

Disclosed are methods and systems for the analysis of testosterone in a sample using supported liquid extraction and liquid chromatography-mass spectrometry.

A sample is cleaned up for spectroscopic analysis by receiving a slide substrate having the sample thereon, fixing the sample to a substrate surface of the slide substrate by applying heat to the slide substrate for a predetermined heating time and incubating the sample on the slide substrate for a predetermined incubation time after fixing the sample to the slide substrate. The sample is further cleaned by washing the sample on the slide substrate after the sample has been incubated and drying the sample by applying heat to the slide substrate for a predetermined drying time, wherein the sample on the slide substrate after drying has retained particles of interest and interferant particles are removed from the substrate. A substrate is also provided for sample collection, which is culturable and Raman silent.

The invention relates to the quantitative measurement of steroidal compounds by mass spectrometry. In a particular aspect, the invention relates to methods for quantitative measurement of steroidal compounds from multiple samples by mass spectrometry.

Methods and systems for selectively capturing analytes, such as cells, e.g., circulating tumor cells (CTCs), from fluid samples are disclosed. The methods include contacting the sample with an analyte binding moiety that selectively binds to the analytes; optionally separating first components of the sample including a majority of the analytes bound to the binding moieties from second components of the sample using size-based separation, e.g., in a microfluidic channel; adding to the first components of the sample a plurality of binding agents under conditions that enable a plurality of the binding agents to be linked to the analyte binding moieties to form multivalent tagging agents bound to the analyte; passing the first components of the sample past a surface to which is attached a plurality of capture agents that selectively bind to the binding agents; and capturing the analytes by providing conditions that enable the multivalent tagging agents bound to the analytes to bind to one or more of the capture agents.

A testing cartridge for metering of a sample to be tested. The testing cartridge includes a casing defining a casing opening and a sliding member defining a sliding member opening. The casing opening or the sliding member opening can define a specified volume, wherein the casing opening and the sliding member opening collectively define a sample application region dimensioned to accommodate receiving an amount of sample exceeding the specified volume. The sliding member is movable transversely to the casing opening by having the sliding member and the casing traverse across each other's respective openings to remove excess sample from the received amount of sample and retain the specified volume from the received amount of sample.

The present invention provides methods for preventing clumping of cells in microfluidic devices by addition of diazolidinyl urea (DU). DU can be added to samples at the time of collection or can be added to samples post-collection. DU can also be pre-added to sample collection devices.

The invention encompasses analyzers and analyzer systems that include a single particle analyzer, methods of using the analyzers and analyzers systems to analyze samples, either for single particles, e.g., protein molecules, or for multiple particles (multiplexing), methods of doing business based on the use of the analyzers or analyzer systems of the system, and electronic media for storing parameters useful in the analyzers and analyzer systems of the invention.

The present invention relates to a high-temperature furnace for T(O)C measurement of a sample, which has a furnace housing which bounds a vaporization space and has a sample opening for the dropwise introduction of the sample and at least one flushing opening for introduction of a flushing liquid. According to the invention, the furnace housing is lined with a spinel ceramic on an inner side facing the vaporization space. By means of the spinel ceramic, the vaporization space is lined with a material which allows particularly high temperatures within the vaporization space and thus very complete combustion and is at the same time very resistant to temperature changes. This allows cleaning with a flushing liquid at essentially the operating temperature of the vaporization space and removal of deposited salts, in particular recrystallized organic salts, from the vaporization space in the flushing liquid in dissolved or undissolved form. Aging of the high-temperature furnace by deposited salts can thereby be avoided or at least significantly retarded.

An apparatus for penetrating a cover over a multi-well sample plate containing at least one individual sample well includes a cutting head, a cutter extending from the cutting head, and a robot. The cutting head is connected to the robot wherein the robot moves the cutting head and cutter so that the cutter penetrates the cover over the multi-well sample plate providing access to the individual sample well. When the cutting head is moved downward the foil is pierced by the cutter that splits, opens, and folds the foil inward toward the well. The well is then open for sample aspiration but has been protected from cross contamination.

Management of the health status of an animal colony using a plurality of blood collection cards and the analysis of dried blood from members of the colony that has been collected on the cards. Members of the colony may be removed from the colony as a result of the analysis.

An automated method for detecting the presence of a nucleic acid in a sample, where the method is performed within a housing of a self-contained, stand-alone analyzer. The method includes purifying the nucleic acid after it has been immobilized on a magnetically-responsive solid support. A pipette of the analyzer is used to form a reaction mixture comprising the purified nucleic acid and all reagents required to perform a nucleic acid amplification. Amplification products are synthesized that include a nucleotide sequence contained in the nucleic acid or the complement of the nucleic acid. The amplification products are exposed to a probe in a mixture, where the probe forms a hybrid with one of the amplification products. The formation of the hybrid in the mixture provides an indication of the presence of the nucleic acid in the sample.

The present liquid sample measuring device comprises a device body on which a biosensor is detachably mounted, a liquid biological sample being dispensed in drops on the biosensor; a measuring section that measures bioinformation from the liquid biological sample; a motion measuring section that measures motion information of the device body; a motion assessment section that assesses the degree of motion of the device body on the basis of the motion information of the device body measured by the motion measuring section; and a measurement controller that adjusts the measurement time for measuring the bioinformation on the basis of the assessment result of the motion assessment section.

A biological sample measuring device including a mounting portion to which a biological sample measuring sensor is mounted, a voltage application section that applies voltage to a counter electrode of the biological sample measuring sensor mounted to the mounting portion, amplifiers that are selectively connected to a working electrode of the biological sample measuring sensor, and a determination section that is connected to these amplifiers. The determination section has a threshold determination section that determines a voltage value obtained by voltage conversion of the current value of the working electrode, a same determination section that selectively connects the amplifiers to the working electrode depending on the determination of the threshold determination section, and identifies the sample deposited on the biological sample measuring sensor from the output of the selected amplifier, and an output section that outputs a measurement value corresponding to the identified sample.

The present invention is a serial to parallel data conversion method and device where new serial data are stored within a first n-bit register prior to presentation at an n-bit parallel output. Subsequently, additional data are stored within a second n-bit register while the data stored within the first register are presented at the parallel output. Data storage and data presentation are thereafter alternated, thereby eliminating the problem of setup time seen in prior art.

In general, this disclosure describes techniques for changing a sampling frequency of a digital signal. In particular, the techniques provide a more accurate way to determining a relative timing between a desired output sample and a corresponding input sample using a non-approximated integer representation of the relative timing. The relative timing between the desired output sample and corresponding input sample may be represented using a first component that identifies a latest input sample of the digital signal used to generate intermediate samples, a second component that identifies an intermediate sample, and a third component that identifies a timing difference between the desired output sample and the intermediate sample. Each of the components may be recursively updated using non-approximated integer values.

A fast gas chromatograph (GC) method and device for obtaining fast gas chromatography analysis, in which a capillary gas chromatography column is inserted into a resistively heated metal tube located mostly outside a heated oven, which serves as a heated transferline to a flexible column that enters a resistively heated metal tube from a gas chromatograph injector and exits into a gas chromatograph detector. The resistively heated metal tube of the fast GC device has an internal diameter that is over twice the external diameter of the GC column so as to enable the insertion of several capillary GC column loops. The process of column insertion into or removal from the heated tube is aided by touching it with an ultrasound vibrating device that remarkably reduces the friction during column insertion into the metal tube heater.

A method, apparatus and system for testing the self-sealing properties of a concrete sample. The method may include providing an apparatus for creating a consistent and reproducible crack in a concrete sample and creating a consistent and reproducible crack in the concrete sample with the apparatus. The method may further include providing a fluidic delivery system that provides a consistent flow of fluid for testing the self-sealing properties of the concrete sample and testing the self-sealing properties of the concrete sample with the system.

An automated method for analyzing seeds generally includes collecting image data from individual seeds using a seed sampling system, determining at least one characteristic of each of the individual seeds based on the collected image data, and removing tissue from each of the individual seeds using the seed sampling system. The method also includes, prior to removing the tissue sample from each of the individual seeds, adjusting at least one operational parameter of the seed sampling system based on the at least one characteristic of the seed from which the tissue is to be removed to thereby allow for generally consistent removal of tissue from each of the individual seeds. In some aspects, the method further includes analyzing the tissue removed from the seeds for presence or absence of at least one characteristic, and selecting seeds based on presence or absence of the at least one characteristic.

A seed sampling system is provided having an automated seed loading assembly including a seed bin and being operable to singulate seeds from a plurality of seeds within the seed bin. The system also includes an automated seed sampling assembly operable to remove tissue samples from the singulated seeds, and an automated seed transport assembly operable to transfer the singulated seeds from the seed loading assembly to the seed sampling assembly. The seed transport assembly includes multiple retention members. Each of the retention members is movable relative to the seed loading assembly and to the seed sampling assembly. The seed transport assembly is operable to position one of the multiple retention members adjacent to the seed loading assembly for engaging one of the singulated seeds, while positioning another of the retention members adjacent to the seed sampling assembly for presenting another of the singulated seeds to the seed sampling assembly.

A method and apparatus for processing seed or seed samples includes an autonomous sorter which sorts seed by pre-programmed criteria. Optional features can include a counter to autonomously ensure the correct number of seeds to a seed package, a cleaning device, a sheller, and a label applicator. A conveyance path, controlled automatically, can move the seed to appropriate and desired stations during the processing while maintaining the sample segregating from other samples. Validation of the sample can be pre-required and information about the sample can be derived and stored for further use.

An automated seed sampler system includes an imaging device for obtaining images of seeds, an orienting device for orienting the seeds based on the images, and a sampling station for removing tissue from the oriented seeds. In some aspects, the system also includes a transport subsystem for supporting the oriented seeds and conveying the oriented seeds to the sampling station. A method for removing tissue from seeds includes imaging the seeds, orienting the seeds based on image information obtained from the seeds, and removing tissue from the oriented seeds. In some aspects, the method also includes transporting the oriented seeds in a transport subsystem to a sampling station for removing the tissue from the oriented seeds, and/or collecting the tissue removed from the oriented seeds so that a one-to-one correspondence exists between the tissue and the sampled seeds, and/or analyzing the tissue for characteristics indicative of genetic and/or chemical traits.

The concentration measurement method includes: introducing a predetermined amount of the biological sample into the capillary; measuring a temperature of the biological sample by applying a first voltage to the electrode unit when the temperature of the biological sample is measured, the first voltage allowing the temperature measurement to be less affected by increase and reduction in an amount of the analyte contained in the biological sample; measuring the concentration of the analyte contained in the biological sample by applying a second voltage to the electrode unit; measuring an environmental temperature in a surrounding of the biological sample; and correcting the concentration of the measured analyte based on the measured temperature of the biological sample and the measured environmental temperature.

The invention discloses methods and devices for rapidly detecting a biological and/or chemical residue in a liquid sample. In some embodiments of the instant invention, a single antenna is generally employed in proximity to an aqueous solution in a disposable cup, with electrical outputs being recorded by an electrical metering device in communication with the single antenna. Commercial plastic cups may be used for detection of electric fields related to cleanliness of water samples. General and specific target detection may be performed with various embodiments of the instant invention.

Devices and methods for characterization of analyte mixtures are provided. Some methods described herein include performing enrichment steps on a device before expelling enriched analyte fractions from the device for subsequent analysis. Also included are devices for performing these enrichment steps.

The present invention refers to a process for classifying tumor samples of unknown and/or uncertain primary origin, specifically including the steps of obtaining patterns of biological activity modulation of tumor of unknown and/or uncertain primary origin and comparing them to an specific and unique group of biomarkers which determine the profiles of biological activity modulation of known origin tumors. The present invention belongs to the molecular biology and genetics field.

Aspects of the present disclosure include methods for processing a biological sample. Methods according to certain embodiments include contacting a biological sample having cells with an assay reagent that includes one or more analyte-specific binding members to produce a biological sample assay composition and introducing the biological assay composition into an inlet of a flow cytometer having an integrated acoustic separator. Systems, including a flow cytometer with integrated acoustic separator having one or more acoustic concentrator devices suitable for practicing the subject methods are also described.

The present invention provides a method for imaging microtentacles on isolated, living, non-adherent primary tumor cells from a cancer subject comprising: i) obtaining one or more living, non-adherent primary tumor cells that has been isolated from a solid tumor from the subject; and ii) imaging the one or more living, non-adherent primary tumor cells and detecting the microtentacles.

The present invention relates to a novel method for detecting a detection object in a sample, and a detection device using the same. The detecting method of the present invention uses a “bridge composite” in which gold nanoparticles and an antibody specific to a detection object are coupled in order to induce a sufficient coupling reaction between the antibody and the detection object, thereby improving reactivity. Accordingly, since excellent resolution is provided, the method of the present invention has advantages of enabling accurate concentration measurement of a detection object in a sample, and amplifying a measurement signal. In addition, the method of the present invention can effectively detect small molecules such as hormones, vitamins, etc. having a small molecular weight.

HighLife Samples has announced the release of a new sample pack by Planet Samples. Trance Vocals Vol. 2 includes 5 vocal construction kits for your next Trance production. The royalty free pack includes dry and wet vocals for each kit, over 20 instruments loops, and 20 MIDI files. For producers looking to simply drag and […]

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IK Multimedia has announced the launch of its Spring Strings Krazy Deal, offering a 73% discount on two of its virtual instrument for a limited time. Get the “bread and butter” virtual instrument sounds you need for your next song or project with SampleTank 4 SE or compose with a living, breathing orchestra with Miroslav […]

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Audentity Records has introduced its latest sample pack Boom Bap Hip Hop 4, a collection of over 200 loops and one-shots. Boom Bap Hip Hop 4 includes atmospheres, brass, fx, synth, guitar, keys, drums & percussion, strings, bass, and more. Our team spent weeks in the studio to bring you one of our best Boom […]

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discoDSP has announced an update to its Bliss performance sampler with built­-in VST host and VSTi sampling. Changes in Bliss v1.8 Added Export Program to mapped WAV files. Added Linux JACK support for standalone. Added Windows ASIO support for standalone. Auto glide mode enabled by default. Delay default value SYNC SYNC 3 ticks. Delay FX […]

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ProducerSpot has announced the launch of its 2020 Spring Sale, offering a 30% discount on all sample packs for a few days only. The sale features hundreds of titles, including some of the latest releases: Hip Hop Essentials by Diginoiz. Uzi Nation by Smemo Sounds. Fast Life by Studio Trap. Osiris Future Chillwave by Certified […]

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Audio Plugin Deals has launched a sale on the Fresh+Dark Bundle by Sampletraxx, offering over 80% off on a collection of three sample libraries. Powered by the full version of Kontakt 5.8, this bundle features the latest sample libraries from SAMPLETRAXX: BRAAMS vol. 2, Rituals and Antisystem. This bundle is perfect for horror, sci-fi and […]

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Impact Soundworks has announced the release of a new sample library with a collection of modern electronic sounds. Cyclops includes over 1,000 one-shots, drum loops, MIDI files, and over 350 presets for the Serum synth by Xfer Records. The library includes drums, playable 808s, arps, basses, leads, pads, poly keys, plucks, fx, and more. This […]

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Indossa has announced the release of Classic Synths for OP-Z, a collection of samples from some classic ’80s ‘odd-ball’ synths, programmed for the OP-Z multimedia synthesizer and sequencer from Teenage Engineering. The pack also comes with some bonus 808 sounds and drum samples. 80’s Synth Waves programmed for OP-Z! Mount your OP-Z in content mode […]

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Cinesamples has launched the World Series Week, offering a 40% discount on a collection of cultural instruments from around the world. World Series instruments are perfect for adding unique and transformative sounds to your scores. In the film composer repertoire, instrumentation is one of many tools that can transform a simple piece of music. At […]

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Ghosthack has announced the release of Ultimate Midtempo Attack, a collection of over 590 sounds for Midtempo productions. Pioneered by producers like REZZ, Gesaffelstein or Aglory, midtempo is quite arguably the hottest new shit out there. Defined through a shredded, thoroughly industrial sound design, dubstep-like bass signatures and tempos around 80-115bpm, in the last years […]

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SampleScience has announced the release of Vaporwaves 2, the grittier followup of the Vaporwaves rompler based around the cheesy sounds of the 80s. All the sounds of Vaporwaves 2 come from an obscure FM synthesizer released in the 80s and have been recorded on second-hand VHS tapes. Modern post-processing techniques have been used to make […]

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Industrial Strength Samples has launched Pharmaceutical Movie Clips sample pack featuring a collection of vocal samples. The content provided has been sorted thru and does not contain any offensive samples that are directed to any one or any one group of people. It’s comical and pretty hardcore at the same time. Pharmaceutical Movie Clips offers […]

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Audentity Records has announced the release of Big Room 2K20, a sample pack featuring a collection of energetic melodies, chords and driving basslines. The pack has a great mixture and balance between Progressive House and EDM, it has all the sounds needed for that Future Progressive House feel. Included are presets for Spire, midis and […]

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SampleScience has announced the release of its free instrument plugin Analog Waveforms, featuring the basic waveforms of the Mopho analog monophonic synthesizer from Dave Smith Instruments. Each waveform has been sampled note by note across 7 octaves (each sample being 10 seconds in length) which gives an accurate and genuine sonic representation of an analog […]

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W.A. Production has released a new What About series sample pack titled Future House String, a collection of sounds inspired by artists like Tchami, Don Diablo, Mesto, and Brook. Get ready for future house fused with deep house and lined with some deep bass progressive attributes. We’ve given you all the elements that you need […]

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Plugin Boutique has launched a sale on the Spiral sample pack featuring 400 designed sound effects inspired by geometry, mathematics and motion. On sale at over 80% off the regular price, the Spiral pack includes 1 GB of content which has been meticulously crafted to compliment modern music, game and multimedia productions in need of […]

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Plugin Boutique has launched an exclusive sale on the Palindrome granular morph plotting sampler by Glitchmachines, offering a 75% discount for the next few days. The basic concept behind Palindrome is to fuse four granular samplers with a coordinate plotting grid and complex modulation sources in order to facilitate the creation of morphing sound effects […]

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HighLife Samples has launched the third volume in the Trance Midi Melodies series of sound packs, delivering a fresh batch of MIDI melodies and samples for Trance producers who want to get instant inspiration for their music productions. The pack includes 20 melodies and 20 bass loops in both MIDI and Wav formats (80 files […]

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Prime Loops has released its new sample pack Homegrown: Hazy Lo-Fi Melodics, a collection of over 190 blissful melodies and lush chord progressions. We’re proud to drop this collection of over 190 simmering, blissful and hazy melodies, perfect for adding that soulful and nostalgic sound to your production, just in time for those Hazy summer […]

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