A simple biomaterial-based strategy that can influence the behavior of cells could pave the way for more effective medical treatments such as wound healing, cancer therapy and even organ regeneration, according to a research team at Penn State.

It is important to reduce embodied carbon in the built environment.

What does the updated OSHA silica regulation mean for spill control?

National Bureau of Economic Research

National Bureau of Economic Research

National Bureau of Economic Research

Two methods for reconstructing intragranular strain fields are developed for scanning three-dimensional X-ray diffraction (3DXRD). The methods are compared with a third approach where voxels are reconstructed independently of their neighbours [Hayashi, Setoyama & Seno (2017). Mater. Sci. Forum, 905, 157–164]. The 3D strain field of a tin grain, located within a sample of approximately 70 grains, is analysed and compared across reconstruction methods. Implicit assumptions of sub-problem independence, made in the independent voxel reconstruction method, are demonstrated to introduce bias and reduce reconstruction accuracy. It is verified that the two proposed methods remedy these problems by taking the spatial properties of the inverse problem into account. Improvements in reconstruction quality achieved by the two proposed methods are further supported by reconstructions using synthetic diffraction data.

A portable self contained light generating device which is powered by a flow of granular material falling under the influence of gravity to impinge upon and cause a paddle wheel to rotate thereby turning a small generator producing electricity to power one or more light emitting diodes for illumination. The device equipped with a multi-position power/illumination control switch and in some embodiments also provided with a battery providing supplemental power.

A granular material stirring apparatus for breaking up clumps of a granular material in an interior of a storage bin comprises a base assembly for resting on a floor of the bin, an agitation rotor rotatably mounted on the base assembly, and a rotation device connected to the rotatable agitation rotor to cause the agitation rotor to rotate with respect to the base assembly. The agitation rotor may include a central member rotatable about a substantially horizontal axis and a plurality of stirrer members extending substantially radially outwardly from the central member to rotate about the substantially horizontal axis.

An apparatus for applying granular material to a rail adjacent to a wheel of a train includes a granular supply material container to which a granular material injection assembly is connected. The granular material injection assembly includes a housing having a mixing chamber. An insert is connected with the housing. A first end portion of the insert has an air inlet through which air flows into the mixing chamber. A second end portion of the insert has an air outlet through which air and granular material flow from the mixing chamber. A valve may be mounted in the air inlet portion of the insert. A venturi may be mounted in the air outlet portion of the insert. A deflector portion of the insert deflects granular material away from a path of flow of air between the air inlet and the air and granular material outlet.

A food dispenser for attaching underneath a cupboard, wherein the dispenser has a bin member having four side walls and a dispensing hatch at a bottom portion thereof, and bin channels formed in top portions of two opposite of the side walls, and a support bracket adapted to be securely attached underneath the cupboard having four side edges, wherein two opposite side edges have support channels adapted to engage respective bin channels of the bin member opposite side walls, such that the bin member can slide on and off the support bracket. The dispensing hatch is pivotally attached to one of the four side walls of the bin member, such that the hatch can be pivotally opened and closed such that food can be extracted from the bin member.

A system for the production of ammonium sulfate granules including a pipe cross reactor (PCR) configured to contact concentrated sulfuric acid with anhydrous ammonia to produce a PCR product comprising ammonium sulfate; and a granulator fluidly connected to the PCR, whereby PCR product extracted from the PCR can be introduced into the granulator, an inlet for ammonium sulfate seed material, an ammonia sparger configured to spray liquid anhydrous ammonia directly onto a bed of ammonium sulfate granules within the granulator, a granulator vent configured for extraction of a vapor comprising unreacted ammonia from the granulator, and a granulator product outlet configured for extraction of granulator product comprising ammonium sulfate granules from the granulator. A method of producing ammonium sulfate granules is also provided.

A granular agrochemical composition is disclosed including a granular core material having a water soluble portion with a first coating layer applied on the surface of the core material and a second coating layer applied on the surface of the first coating layer. The first coating layer includes a wax composition having a biologically active ingredient incorporated therein and the second coating layer includes a polymeric composition. The granular agrochemical composition exhibits a controlled rate of release of the biologically active ingredient therefrom over a period greater than about 30 days from the date of initial exposure of the granular composition to moisture whereby essentially all of the biologically active ingredient incorporated in the wax material of the first coating layer is released from the granular composition before the water soluble portion of the granular core material is released from the granular composition.

Plugin Boutique has launched an exclusive sale on the Palindrome granular morph plotting sampler by Glitchmachines, offering a 75% discount for the next few days. The basic concept behind Palindrome is to fuse four granular samplers with a coordinate plotting grid and complex modulation sources in order to facilitate the creation of morphing sound effects […]

The post Glitchmachines Palindrome granular sampler plugin on sale at $19 USD appeared first on rekkerd.org.

How small the pieces are. When a system is split into components, it's important to get the right degree of componentization. Small, fine-grained components give much greater flexibility in assembling precisely the right combination of functionality, but they are more difficult to co-ordinate. Much larger, coarse-grained components are easier to manage but may become too unwieldy. Performance and management considerations tend to favor the use of more coarsely grained messages in a service oriented architecture, whereas earlier generations of distributed computing have preferred a much finer level of granularity.

Tlarge granular lymphocyte leukemia (T-LGLL) is characterized by the expansion of several large granular lymphocyte clones, among which a subset of large granular lymphocytes showing constitutively activated STAT3, a specific CD8⁺/CD4^– phenotype and the presence of neutropenia has been identified. Although STAT3 is an inducer of transcription of a large number of oncogenes, so far its relationship with miRNAs has not been evaluated in T-LGLL patients. Here, we investigated whether STAT3 could carry out its pathogenetic role in T-LGLL through an altered expression of miRNAs. The expression level of 756 mature miRNA was assessed on purified T large granular lymphocytes (T-LGLs) by using a TaqMan Human microRNA Array. Hierarchical Clustering Analysis of miRNA array data shows that the global miRNome clusters with CD8 T-LGLs. Remarkably, CD8 T-LGLs exhibit a selective and STAT3-dependent repression of miR-146b expression, that significantly correlated with the absolute neutrophil counts and inversely correlated with the expression of Fas ligand (FasL), that is regarded as the most relevant factor in the pathogenesis of neutropenia. Experimental evidence demonstrates that the STAT3-dependent reduction of miR-146b expression in CD8 T-LGLs occurs as a consequence of miR-146b promoter hypermethylation and results in the disruption of the HuR-mediated post-transcriptional machinery controlling FasL mRNA stabilization. Restoring miR-146b expression in CD8 T-LGLs lead to a reduction of HuR protein and, in turn, of FasL mRNA expression, thus providing mechanistic insights for the existence of a STAT3-miR146b-FasL axis and neutropenia in T-LGLL.

Barker Library - TA357.5.G47 M38 2014

Barker Library - TA418.78.F76 2018

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