ces Numéricable Selects Calix and Arcadiz for Broadband Business Services Rollout By www.tvover.net Published On :: Tue, 16 Oct 2012 20:57:53 GMT Numéricable has selected the Calix E7-2 Ethernet Service Access Platform and gigabit passive optical network technology to upgrade its service delivery platform in Belgium and Luxembourg. Calix, along with optical specialist Arcadiz Telecom, will work closely to roll out Numéricable’s new high-speed broadband networks to deliver business services across the region. The new platform will enable Numéricable’s customers to take advantage of advanced voice, video, and data services at symmetrical speeds ranging from 30 megabits per second (30 Mbps) up to 1 gigabit per second (1 Gbps). Numéricable serves over 150,000 customers in Brussels with triple-play services for residential subscribers. Owned by Coditel and with a close relationship to the French Numéricable organization, with whom it shares a range of resources, Numéricable Belgium is a long-established operator with a highly dispersed coax cable network. The company has traditionally delivered triple-play residential services over its hybrid fiber coax infrastructure, but in recent years has moved increasingly towards using its fiber to connect businesses and has developed a number of specific niche markets. The company is now looking at ways to maximize the potential of its fiber infrastructure in Belgium and Luxembourg and deliver revenue-generating advanced services to its business customers. Full Article Service Providers/Europe IPTV
ces Sure Chooses Netgem for its Advanced Hybrid TV Services By www.tvover.net Published On :: Thu, 18 Oct 2012 20:21:49 GMT Netgem announced that Sure has partnered with Netgem to launch a new hybrid IPTV service for its customers in the Channel Islands and the Isle of Man. By working with Netgem, Sure has been able to make use of its broadband network to deliver Over the Top live and non-linear content to a hybrid STB. This means the operator can now add premium TV to its bouquet of services and offer its customers triple and quad play packages. The new service is powered by Netgem's N8200 hybrid PVR integrating its nCloud middleware; subscribers will benefit from a brand-new TV experience that supplements UK DVB-T2 free-to-air channels for popular non-linear entertainment content and a fluid and consistent user interface. Full Article IPTV Middleware;Service Providers/Europe IPTV
ces Orange Extends Services with Interactive TV and Mobile Apps By www.tvover.net Published On :: Thu, 18 Oct 2012 20:25:16 GMT Orange Slovensko the leading telco operator on the market uses the nangu.TV Media Platform for IPTV and OTT delivery. "With the growing demand for interactive television and more viewing possibilities, Orange sought a proven solution to bring to the market," says Product Manager at Orange, Martin Hainzl. Orange offers their customers TV with value added features, which gives them more options and comfort than classic live TV. The VoD selection stores 50 movie titles, accessible on multiple screens: TV, PC, Smartphone or tablet. The TV Archive allows playback of content up to 7 days in the past. Customers can utilize the time shift feature to browse content already aired and watch it at their leisure with pause, play and star t over commands. They have flexibility in watching television on the go with the newly released applications for both iOS and Android devices. The nangu.TV solution allows operators to stay ahead of competition by giving cutomers the chance to be in control of how they watch TV. Full Article Interactive TV;Mobile TV
ces Octoshape and INVISO Partner Up to Offer Internet-Based TV Contribution Services Across Latin America By www.tvover.net Published On :: Fri, 26 Oct 2012 20:56:01 GMT Octoshape announced a partnership with INVISO to deliver Internet TV contribution services throughout Latin America. "At INVISO, we seek the most innovative and high quality products to serve our customers through the brands we represent,” said Jose Luis Reyes, Vice President for Sales and Operations, INVISO. “In the case of Octoshape, we found a company and a product that bring these qualities to our supply chain, sales and service.” Octoshape offers an innovative cloud-based solution that provides instant infrastructure for the distribution of both linear and video on demand content. The Octoshape Infinite Uplink service provides point-to-point distribution of TV signals over the Internet for source signal acquisition to traditional IPTV and cable headends as an alternative to traditional methods like satellite and video fiber. Full Article Internet TV;Service Providers/South America IPTV
ces Dune HD Enhances Quality of IPTV Experience with Qarva FastSwitch By www.tvover.net Published On :: Tue, 30 Oct 2012 21:07:01 GMT Dune HD announces a new partnership with Qarva designed to enhance the IPTV experience. The integration of Qarva’s FastSwitch technology into Dune HD’s digital media players and set-top boxes will give IPTV subscribers improved interaction and higher quality through faster channel changing and the elimination of packet loss. The joint solution will be demonstrated by Dune HD on stand 17 at TV Connect MENA 2012. An enhanced, high quality experience is proven to increase subscriber loyalty and is central to operators reducing churn and growing revenues. FastSwitch improves the viewing experience by dramatically reducing the lag associated with controlling IPTV services, bringing response times down from 5 seconds to less than half a second - in line with the speeds achieved through traditional TV broadcast channels. Through its integral Packet Loss Recovery technology, FastSwitch also eliminates IPTV issues such as picture freezing and blocking, delivering an improved viewing performance. Full Article IPTV Set-Top Boxes
ces The Digital Development Group is Seeing Tremendous Growth in Holiday Sales for Internet TV Devices By www.tvover.net Published On :: Tue, 27 Nov 2012 21:26:26 GMT The Digital Development Group foresees dynamic growth in its industry. “On Nov. 21st we launched our first channel. We are excited to announce 5 more channels coming before year-end. On the heels of those developments we believe it is important to continue to define our mission.” DigiDev is targeting the revolutionary “OTT” technology arena. “OTT” or Over The Top devices piggyback on existing network services in consumers’ homes or offices; pull content from the Internet and deliver it to their TV or Internet enabled device. DigiDev uses OTT technology to deliver programming to billions of desktops, mobile and smart/Internet enabled TV devices around the world. “The market for digital distribution to 'smart' (Internet enabled) devices (smart-TV, tablet, smart-phones) continues to grow at an astonishing rate,” states Martin W. Greenwald, Chairman and CEO of DigiDev. “AppleTV, GoogleTV, and Roku sales this Holiday season are running considerably ahead of last year’s tally.” Full Article Internet TV
ces Trump has a dream team for mismanaging a recession By www.washingtonpost.com Published On :: Thu, 15 Aug 2019 21:45:29 +0000 If we have an economic downturn, it will be bad. Full Article
ces Don’t root for a recession to knock out Trump By www.washingtonpost.com Published On :: Mon, 06 Jan 2020 23:51:12 +0000 There are better ways to challenge Trump on the economy. Full Article
ces With coronavirus, Trump’s lies and his reassurances backfire By www.washingtonpost.com Published On :: Thu, 27 Feb 2020 23:40:57 +0000 Americans have not only health risks but also economic fears. Full Article
ces Officials have spent the last few years dismantling anti-recession measures By www.washingtonpost.com Published On :: Thu, 12 Mar 2020 22:49:43 +0000 And now, we’re woefully unprepared. Full Article
ces A global recession is likely here. Lawmakers need to do their jobs. By www.washingtonpost.com Published On :: Mon, 16 Mar 2020 23:13:02 +0000 Policymakers need to step up and do something useful — yesterday. Full Article
ces Teaching My Daughters to Read. Part IV: Success By feedproxy.google.com Published On :: Tue, 31 Mar 2020 12:00:58 EDT Previously, I described how I taught my daughters about print, sight vocabulary, phonological awareness, Full Article
ces Literacy for All: Equitable Practices for Reading and Dyslexia By feedproxy.google.com Published On :: Tue, 14 Apr 2020 18:36:06 EDT Teaching students to read is the first job of our schools. How can we help all students become strong, confident readers? Literacy for All: Equitable Practices for Reading and Dyslexia was held on February 20, 2020 in Annapolis, Maryland. The event was hosted by National Center on Improving Literacy (NCIL), Decoding Dyslexia Maryland (DD-MD), and community partners. Reading experts from NCIL shared best practices in early screening and interventions supported by decades of reading research. Full Article
ces How to Switch AirPods Between Devices (iPhone, iPad, Mac, Apple Watch) By feedproxy.google.com Published On :: Fri, 01 May 2020 15:50:02 +0000 How would you like to switch AirPods between iPhone, iPad, and Mac? Or what if you’d like to switch AirPods from iPhone to Apple Watch or even Apple TV? If you have a pair of AirPods and multiple Apple devices, you can easily switch AirPods and AirPods Pro between any of your other Apple products, ... Read More Full Article Apple TV Apple Watch iPad iPhone Mac OS X Tips & Tricks AirPods AirPods Pro iPod Touch Mac macOS Sharing tips tricks
ces oscon: Just 1 week left to take advantage of #OSCON early registration prices. Register by 6/6 to save http://t.co/E0JKpcj1Rp #opensource By twitter.com Published On :: Fri, 31 May 2013 00:05:10 +0000 oscon: Just 1 week left to take advantage of #OSCON early registration prices. Register by 6/6 to save http://t.co/E0JKpcj1Rp #opensource Full Article
ces oscon: Only 48 hours left to get discounted tickets to #OSCON. Early registration prices end tomorrow at midnight http://t.co/E0JKpcj1Rp By twitter.com Published On :: Wed, 05 Jun 2013 15:05:42 +0000 oscon: Only 48 hours left to get discounted tickets to #OSCON. Early registration prices end tomorrow at midnight http://t.co/E0JKpcj1Rp Full Article
ces oscon: Tutorials at #OSCON are filing up (some already sold out). Register soon to get your top choices http://t.co/bQv7k8VXTf By twitter.com Published On :: Mon, 10 Jun 2013 21:06:28 +0000 oscon: Tutorials at #OSCON are filing up (some already sold out). Register soon to get your top choices http://t.co/bQv7k8VXTf Full Article
ces oscon: Easily Invoke Common Protocols with Twisted - Spin up Python-friendly services with 0 lines of code http://t.co/29oTkk0isW By twitter.com Published On :: Tue, 11 Jun 2013 16:40:44 +0000 oscon: Easily Invoke Common Protocols with Twisted - Spin up Python-friendly services with 0 lines of code http://t.co/29oTkk0isW Full Article
ces Literacy for All: Equitable Practices for Reading and Dyslexia By feedproxy.google.com Published On :: Tue, 14 Apr 2020 18:36:06 EDT Teaching students to read is the first job of our schools. How can we help all students become strong, confident readers? Literacy for All: Equitable Practices for Reading and Dyslexia was held on February 20, 2020 in Annapolis, Maryland. The event was hosted by National Center on Improving Literacy (NCIL), Decoding Dyslexia Maryland (DD-MD), and community partners. Reading experts from NCIL shared best practices in early screening and interventions supported by decades of reading research. Full Article
ces OReilly announces certification guides for the most in-demand IT and professional certifications By www.oreilly.com Published On :: Mon, 16 Mar 2020 17:11:23 PDT Full Article
ces OReilly opens up learning platform access for all government agencies to help navigate the crisis By www.oreilly.com Published On :: Mon, 06 Apr 2020 15:08:29 PDT Full Article
ces Fin24.com | MTN slashes data prices By www.fin24.com Published On :: Fri, 20 Mar 2020 12:45:51 +0200 MTN on Friday announced a drop in the price of monthly data bundles and customers will now pay R99 for 1GB, 33% lower than previously. Full Article
ces Fin24.com | Datatec sees increased demand for its remote access computing By www.fin24.com Published On :: Mon, 23 Mar 2020 15:09:28 +0200 Datatec tells shareholders that the rapidly spreading coronavirus outbreak has reached every region where the group operates. Full Article
ces Literacy for All: Equitable Practices for Reading and Dyslexia By feedproxy.google.com Published On :: Tue, 14 Apr 2020 18:36:06 EDT Teaching students to read is the first job of our schools. How can we help all students become strong, confident readers? Literacy for All: Equitable Practices for Reading and Dyslexia was held on February 20, 2020 in Annapolis, Maryland. The event was hosted by National Center on Improving Literacy (NCIL), Decoding Dyslexia Maryland (DD-MD), and community partners. Reading experts from NCIL shared best practices in early screening and interventions supported by decades of reading research. Full Article
ces 4 High-Potential Sectors for AI and ML Startup Success By feedproxy.google.com Published On :: Wed, 01 Jan 2020 19:00:21 +0000 Today, the explosion of development in artificial intelligence (AI) and machine learning (ML) technology has created a market for which it appears there’s no limit. No matter the industry, if you name a reasonably-sized (or larger) company, there’s a good chance that they’re investing in AI and ML technology as a cornerstone of their strategic […] The post 4 High-Potential Sectors for AI and ML Startup Success appeared first on ReadWrite. Full Article AI Startups artificial intelligence HR Human Resources Machine Learning ML startups
ces Successful Scaling: How to Grow Without Tumbling Back Down By feedproxy.google.com Published On :: Mon, 06 Jan 2020 23:00:10 +0000 “Breathing would be delightful,” the director of products told me in our kickoff. His startup was growing fast. It had a bunch of new funding, the pressure was on to ship, and the team was underwater. I was there to help and take the pressure off so they could breathe. “Let’s begin to think strategically […] The post Successful Scaling: How to Grow Without Tumbling Back Down appeared first on ReadWrite. Full Article ReadWrite
ces Help us chart how marketers are feeling about in-person conferences and trade shows By feeds.searchengineland.com Published On :: Tue, 05 May 2020 14:12:22 +0000 We want to know how your thoughts on attending live person events through the end of this year. Please visit Search Engine Land for the full article. Full Article
ces velocityconf: Help your dev + ops teams be cross-functional and more successful. http://t.co/1mqGK3zh0U Free webcast 5/22 w/ @lnxchk By feedproxy.google.com Published On :: Mon, 20 May 2013 16:58:59 +0000 velocityconf: Help your dev + ops teams be cross-functional and more successful. http://t.co/1mqGK3zh0U Free webcast 5/22 w/ @lnxchk Full Article
ces News24.com | Suspected zama zamas arrested while allegedly processing gold in Limpopo By www.news24.com Published On :: Sat, 09 May 2020 12:47:47 +0200 Eight suspected illegal miners, known as zama zamas, have been arrested in Limpopo, following a Hawks investigation. Full Article
ces Channel24.co.za | WATCH NOW: She’s a Joburg princess who moves to Cape Town and must now plan her wedding! By www.channel24.co.za Published On :: Tue, 21 Apr 2020 11:38:10 +0200 This episode of Tali's Wedding Diary is proudly shared with you by Channel24 and Showmax. Full Article
ces Channel24.co.za | SA's film and TV industry back to work amid Covid-19 – without extras or studio audiences By www.channel24.co.za Published On :: Thu, 07 May 2020 10:14:25 +0200 South Africa's film and TV industry got the green-light to reopen but as cameras start rolling and lights flicker back on it won't be business as usual. Full Article
ces Channel24.co.za | 'Isibaya' actress Asavela Mngqithi announces pregnancy By www.channel24.co.za Published On :: Fri, 08 May 2020 07:48:28 +0200 'Isibaya' actress Asavela Mngqithi announced that she is pregnant on Instagram. Full Article
ces News24.com | Man arrested for spate of lockdown robberies in Tshwane, 'accomplices' killed in shootout with cops By www.news24.com Published On :: Sat, 09 May 2020 11:25:51 +0200 An alleged robber, who was wounded while his two suspected accomplices were killed in a shootout with police, has been arrested. Full Article
ces 4 Omnichannel Marketing Best Practices for eCommerce By feedproxy.google.com Published On :: Wed, 27 Feb 2019 00:00:00 +0000 Nowadays many shoppers don’t even remember how they learned about an eCommerce brand in the first place. If you ask them, the most popular answer is “I found it somewhere on the Internet”. Commercial information is all over the place, so nobody cares about the “channel” they use to find it anymore. Full Article
ces 4 Omnichannel Marketing Best Practices for eCommerce By feedproxy.google.com Published On :: Wed, 27 Feb 2019 00:00:00 +0000 Nowadays many shoppers don’t even remember how they learned about an eCommerce brand in the first place. If you ask them, the most popular answer is “I found it somewhere on the Internet”. Commercial information is all over the place, so nobody cares about the “channel” they use to find it anymore. Full Article
ces How Offices Are Preparing for Workers' Return By feedproxy.google.com Published On :: Thu, 07 May 2020 00:00:00 -0500 From smartphone-operated elevators to contactless coffee machines, businesses are trying to eliminate major touchpoints to help deter coronavirus spread in the workplace. Full Article
ces Huge Group of California Churches Announces Plan To Defy Governor Newsom’s Order By www.westernjournal.com Published On :: Sat, 09 May 2020 02:21:33 +0000 An evangelical church network in California will ignore Democratic Gov. Gavin Newsom’s executive prohibitions this month, opening sanctuary doors for communal worship despite the ongoing coronavirus pandemic. According to Fox News, California Church United, representing roughly 3,000 churches and 2.5 million congregants statewide, announced Thursday that it will return to conducting in-person services by Pentecost… The post Huge Group of California Churches Announces Plan To Defy Governor Newsom’s Order appeared first on The Western Journal. Full Article News California Christianity Coronavirus Culture Faith Politics US News
ces Famous Faces Who Passed Away in April 2020 By www.westernjournal.com Published On :: Sat, 09 May 2020 16:13:49 +0000 Celebrity Deaths in April 2020 Here’s a look at some of the famous faces we lost in the month of April. Ellis Marsalis Jr. Ellis Marsalis, 1934 – 2020 He went out the way he lived: embracing reality pic.twitter.com/sPyYUuBoIG — Wynton Marsalis (@wyntonmarsalis) April 2, 2020 New Orleans jazz legend Ellis Marsalis Jr., 85, died on… The post Famous Faces Who Passed Away in April 2020 appeared first on The Western Journal. Full Article Lifestyle News Celebrity Coronavirus death Entertainment Health Hollywood US News
ces Four Providers’ Houston Data Centers Online, but Access Roads Flooded By feedproxy.google.com Published On :: Mon, 28 Aug 2017 19:50:15 +0000 Full Article Colocation Manage Uptime
ces Hurricane Harvey: Delivering Managed IT Services During a Catastrophe By feedproxy.google.com Published On :: Tue, 29 Aug 2017 15:00:00 +0000 Full Article Manage North America Uptime
ces A Campaign of Disappearances in Syria Leaves Thousands Missing By feedproxy.google.com Published On :: Thu, 05 Nov 2015 18:54:46 EST At least 65,116 individuals have been "forcibly disappeared" by the Syrian government, according to a new report by Amnesty International. Full Article
ces Great leaders inspire innovation and creativity from within their workforces By feedproxy.google.com Published On :: Mon, 23 Mar 2020 09:57:00 +0000 Rita J. King, co-director and EVP for business development at Science House, recently conducted a series of interviews with business leaders, exploring the challenges and hurdles companies face in evolving business landscapes. In this interview, King chats with James Jorasch, founding CEO of Science House, about the importance of innovation and how to inspire and […] Full Article Future of the Firm Big Systemic Thinking
ces Leaders need to mobilize change-ready workforces By feedproxy.google.com Published On :: Mon, 23 Mar 2020 09:58:00 +0000 Rita J. King, co-director and EVP for business development at Science House, recently conducted a series of interviews with business leaders, exploring the challenges and hurdles companies face in evolving business landscapes. In this interview, King chats with Jen Bruno, SVP of culture and human capital at LPL Financial, about mobilizing a change-ready workforce, leadership […] Full Article Future of the Firm Big Systemic Thinking
ces Webinars are a hugely successful marketing tool and this software can help you launch one By feedproxy.google.com Published On :: Fri, 08 May 2020 13:00:22 PDT If you’re an entrepreneur or marketer who hasn’t embraced webinars yet, you probably need to rethink your strategies. Over 60 percent of marketers say they use webinars as a key part of their content marketing strategy — and over 70 percent say it’s the best way to generate high-quality business leads. Thankfully, one of the silver linings to our new quarantine, work from home lifestyles lately is the explosion of conferencing software and Americans’ newfound enthusiasm for video group meetups. Vidthere is one of the services that has considered the needs of large and small groups trying to maintain connections over distance, offering a suite of web-based communication tools that centralizes everything in one easy-to-use place. Vidthere is a live video platform for everyone, featuring loads of internal communications features as well as options to sell and market directly to customers. With webinars emerging as a key means to engage customers and sell products, Vidthere gives you all the tools to do that from any location. Vidthere offers the opportunity to deliver live video webinars that are easy for both presenters and users. Vidthere is entirely web-based, so users never need to download any software to join a Vidthere session. As for sessions, they combine no-lag high-quality performance with the ability to scale to the size of an audience with no video loss. Plus, every Vidthere meeting or webinar has a powerful chat feature so users can engage easily. As for presenters, Vidthere events support up to 30 meeting participants and an unlimited number of webinar viewers, with options to support screen sharing, video in video presentation, and a whiteboard mode, a full basket of tools to help contour any presentation just the way you want it. Read the rest Full Article Post shop
ces 9 Online Resources for Effective Learning By feedproxy.google.com Published On :: Mon, 04 May 2020 18:00:00 +0000 Technology is continuously leaving an indelible mark on many conceivable fields and industries, and education hasn’t been left behind either. Today, you no longer need to take admission classes and physically attend all your classes to earn a degree. All that is required of you is a working web connection and an incontestable thirst for […] The post 9 Online Resources for Effective Learning appeared first on Dumb Little Man. Full Article College Learning Technology
ces BREAKING: Sen Marsha Blackburn Introduces Stop COVID Act…Allowing US Citizens To Sue Communist China For Damage They’ve Inflicted On Our Nation By 100percentfedup.com Published On :: Wed, 06 May 2020 16:56:18 +0000 The following article, BREAKING: Sen Marsha Blackburn Introduces Stop COVID Act…Allowing US Citizens To Sue Communist China For Damage They’ve Inflicted On Our Nation, was first published on 100PercentFedUp.com. Yesterday, Senator Marsha Blackburn (R-TN), along with Senator Martha McSally (R-AZ) introduced the Stop COVID Act, giving Americans the ability to sue Communist China for the damage they’ve inflicted on our nation. Senator Blackburn appeared on Fox News with host Judge Jeanine where she explained the act to Jeanine Pirro. Blackburn told the Fox News […] Continue reading: BREAKING: Sen Marsha Blackburn Introduces Stop COVID Act…Allowing US Citizens To Sue Communist China For Damage They’ve Inflicted On Our Nation ... Full Article Featured Politics
ces ‘Schiff in Panic Mode’: Sources Say Russia Probe Transcripts Affirm Officials Found Nothing on Collusion By 100percentfedup.com Published On :: Thu, 07 May 2020 13:44:13 +0000 The following article, ‘Schiff in Panic Mode’: Sources Say Russia Probe Transcripts Affirm Officials Found Nothing on Collusion, was first published on 100PercentFedUp.com. Transcripts of House Intelligence Committee interviews have been cleared for release, and Adam Schiff is reportedly in panic mode. Unfortunately for Schiff, top law enforcement and intel officials said they saw no evidence of collusion between the Trump campaign and Russia in the transcripts. Republicans sought and got approval for the release of the transcripts […] Continue reading: ‘Schiff in Panic Mode’: Sources Say Russia Probe Transcripts Affirm Officials Found Nothing on Collusion ... Full Article Breaking Featured Politics
ces Mother of the Year, Michelle Obama Explains How Having Kids Was A “Concession”… Had To Give Up Her “Aspirations and Dreams” [VIDEO] By 100percentfedup.com Published On :: Fri, 08 May 2020 00:05:56 +0000 The following article, Mother of the Year, Michelle Obama Explains How Having Kids Was A “Concession”… Had To Give Up Her “Aspirations and Dreams” [VIDEO], was first published on 100PercentFedUp.com. While campaigning for her community organizer turned presidential candidate husband, Barack, Michelle Obama told a crowd of his supporters in Milwaukee, Wisconsin that for the first time in her life, she was proud to be an American. Four years later, Michelle Obama was a keynote speaker at the DNC convention, where she told Democrats how […] Continue reading: Mother of the Year, Michelle Obama Explains How Having Kids Was A “Concession”… Had To Give Up Her “Aspirations and Dreams” [VIDEO] ... Full Article Featured Left News Politics
ces COVID-19 outbreak at Health Sciences Centre declared over By winnipeg.ctvnews.ca Published On :: Fri, 8 May 2020 13:34:00 -0600 Health officials with the Manitoba government announced on Friday that a COVID-19 outbreak at the Health Sciences Centre has officially been declared over. Full Article
ces Inhibition of the erythropoietin-producing receptor EPHB4 antagonizes androgen receptor overexpression and reduces enzalutamide resistance [Molecular Bases of Disease] By feedproxy.google.com Published On :: 2020-04-17T00:06:05-07:00 Prostate cancer (PCa) cells heavily rely on an active androgen receptor (AR) pathway for their survival. Enzalutamide (MDV3100) is a second-generation antiandrogenic drug that was approved by the Food and Drug Administration in 2012 to treat patients with castration-resistant prostate cancer (CRPC). However, emergence of resistance against this drug is inevitable, and it has been a major challenge to develop interventions that help manage enzalutamide-resistant CRPC. Erythropoietin-producing human hepatocellular (Eph) receptors are targeted by ephrin protein ligands and have a broad range of functions. Increasing evidence indicates that this signaling pathway plays an important role in tumorigenesis. Overexpression of EPH receptor B4 (EPHB4) has been observed in multiple types of cancer, being closely associated with proliferation, invasion, and metastasis of tumors. Here, using RNA-Seq analyses of clinical and preclinical samples, along with several biochemical and molecular methods, we report that enzalutamide-resistant PCa requires an active EPHB4 pathway that supports drug resistance of this tumor type. Using a small kinase inhibitor and RNAi-based gene silencing to disrupt EPHB4 activity, we found that these disruptions re-sensitize enzalutamide-resistant PCa to the drug both in vitro and in vivo. Mechanistically, we found that EPHB4 stimulates the AR by inducing proto-oncogene c-Myc (c-Myc) expression. Taken together, these results provide critical insight into the mechanism of enzalutamide resistance in PCa, potentially offering a therapeutic avenue for enhancing the efficacy of enzalutamide to better manage this common malignancy. Full Article