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In strategy game Sintopia you harvest a whole civilisation's souls for your own custom-built hell

One of my favourite satires is the Screwtape Letters, an epistolary novel by Narnia scribe C.S. Lewis. It consists of messages from an oily elder demon to his nephew about how to correctly groom the soul of an unsuspecting human being. It's a claustrophobic send-up of managerial politics and nepotism, with World War 1 unfolding in the background. A real pick-me-up. Sintopia is the Two Point incarnation of that premise - in other words, brighter and breezier and definitely more slapstick than Christian. It puts you in charge of a world divided between Earth and hell, and challenges you to ensure a steady movement of optimally sinful souls between one and the other. Say your prayers and watch the trailer.

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Trump Builds New Administration

Friday on the RealClearPolitics radio show -- weeknights at 6:00 p.m. on SiriusXM's POTUS Channel 124 and then on Apple, Spotify, and here on our website -- Tom Bevan, Andrew Walworth, and Carl Cannon look at the latest count to determine the final popular vote and House majority.




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'More than 100' Post Office branches and 'hundreds of jobs at risk' after strategic review



As many as 115 Post Office Branches and hundreds of jobs could be at risk following a strategic review held by Post Office Chairman Nigel Railton.




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RFK Jr. launches online forum to crowdsource names for 4,000 Trump administration nominees

Robert F. Kennedy Jr. launched a "Nominees for the People" forum to crowdsource 4,000 positions in the Trump administration to Make America Healthy Again.



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Fox News Politics: Administration of Allies

The Fox News Politics newsletter, with the latest updates on the Trump transition, exclusive interviews and more Fox News politics content.



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Biden-Harris Administration Decides Not to Cut Arms to Israel, After Threat


The State Department said Tuesday that the Biden-Harris administration would not cut off weapons supplies to Israel in reaction to what it said was a declining humanitarian situation in the Gaza Strip, due to Israeli mitigation efforts.

The post Biden-Harris Administration Decides Not to Cut Arms to Israel, After Threat appeared first on Breitbart.




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Donald Trump's Administration Takes Shape After 15 Official or Expected Picks


President-elect Donald Trump has made many selections to lead his administration as his transition gets underway, ranging from chief of staff to head of the Environmental Protection Agency (EPA). At the same time, a number of crucial positions have yet to be filled just one week removed from the landslide election.

The post Donald Trump’s Administration Takes Shape After 15 Official or Expected Picks appeared first on Breitbart.




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Metal Slug Tactics gives turn-based strategy a hyper-stylized shot of adrenaline

It's a little rogue-lite, it's a bit '90s arcade, and it's surprisingly deep.




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Teenaged Shola Jimoh impresses at men's soccer training session, offering evidence of CPL development strategy

It didn't take long to see what makes 16-year-old Shola Jimoh a prospect for Canada's men's soccer team. In a frenzied training session on Wednesday, he was always on the attack, always on the balls of his feet, leaving coach Jesse Marsch impressed.



  • Sports/Soccer/CPL

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Open World Dress Up Game ‘Infinity Nikki’ Gets New Trailer With Closed Beta Sign Ups Now Live, Pre-Registrations Also Available

Another mobile reveal from Gamescom Opening Night Live 2024 was the latest trailer for the open world dress up game …




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Administration Trump: un «faucon» anti-Chine comme secrétaire d'État, une «tueuse de chiens» à la Sécurité intérieure

Un «faucon» anti-Chine à la diplomatie, une gouverneure «tueuse de chiens» à la sécurité intérieure.




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Trump’s Administration Will Attack Health Care from Multiple Angles

The new Trump administration is likely to reduce subsidies for Affordable Care Act insurance plans and roll back Medicaid coverage. Public health authorities worry that antivaccine activist Robert F. Kennedy, Jr., will be empowered




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Trump Administration Likely to Repeal Methane Leak Penalty

A fee created to push oil and gas companies to plug methane leaks could be axed by the incoming Trump administration, hampering efforts to curb the potent greenhouse gas




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Informa Connect’s Trade and Channel Strategies

Informa Connect’s Trade and Channel Strategies
December 10-12, 2024 at the W Hotel in Philadelphia, PA
Drug Channels readers save 10% with code 24DC10*

Pharmacy and distribution models are growing increasingly complex. Stop running in circles—It’s time to unlock proven strategies to propel market access.

What is the secret to success? Trade and Channel Strategies is bringing together industry experts to deliver specific strategies and talk best practices in tackling the latest industry challenges.

As the landscape rapidly evolves, there are only two choices—Adapt or risk falling behind. With policy changes and market fluctuations, specifically surrounding the DSCSA and IRA, the loss of exclusivity wave, adoption of low-WAC products affecting GTN and the rise of innovations within the pharmacy sector, there has never been a more important time for industry to unite. A program driven by market dynamics and led by champions of channel strategy, join your peers now to master the complexities of pharmacy and distribution models to accelerate market access—It's all happening December 10-12.

Why do trade and channel professionals choose this pivotal event?

The challenge of staying viable among shifting market dynamics while meeting business objectives is heavy. Professionals are left with many questions, including:
  • How will the new administration affect the distribution channel?
  • Is my organization haemorrhaging money to stay afloat with the shift to alternative distribution and pharmacy models?
  • Does the DSCSA deadline change affect my organization? Am I still prepared?
Join the experts for three dedicated days of collaborative discussions that will give you the answers to these questions and so many more. Leaders in the landscape are uniting and will dive into the top trends for innovative distribution, integrated pharmacy models and talk the truth about the future of trade.

WHAT CAN YOU EXPECT?

Vital insights from industry’s leading pharmacy and distribution experts, including:
  • Bill Roth, Senior Vice President of Consulting, Blue Fin Group, An IntegriChain Company
  • Patrick Lupo Group Vice President, Pharmacy Trade and Specialty, Walgreens
  • Amanda Salindong, Associate Director, Channel & Distribution, Alnylam Pharmaceuticals
  • Chris Rocco, Senior Director, Market Access Data, Reporting & Analytics, GSK
  • Eliane Maalouf, Director Trade and Fulfillment, Mass General Brigham Specialty Pharmacy
  • Stephanie Wirkes, Head of Distribution and Strategy Execution, Bayer
  • John Harlow, Chief Commercial Officer, Melinta Therapeutics
  • Aria Cohen, Vice President, Head of Market Access, Alkeus Pharmaceuticals, Inc.
  • Elizabeth Cherry, Program Director for Trade Relations, Vanderbilt Specialty Pharmacy
  • Danielle Bryan, PharmD, CSP, Program Director, Specialty Pharmacy Trade Relations, Vanderbilt University Medical Center
  • Thomas Scalone, Director, Trade Strategy and Operations, Bristol Myers Squibb
  • Dina Lynch, VP, Market Access and Reimbursement, Renibus Therapeutics
  • And more!
Tackle the hottest topics facing industry right now, including:
  • Keynote Address: Access and Channel 2024 In-Review and Preview of 2025
  • Pharmacy Evolved—Aligning Commercialization to the Changing Pharmacy Channel
  • Advanced Trade Leaders Executive Session
  • Navigate and Operationalize the IRA
  • Focused Multi-Track Offerings:
    • Supply Chain, Distribution and Logistics
    • Pharmacy Models and Reimbursement Strategies
    • Data, Innovation and Analytics
    • Health Systems and Pharma Partnering Symposium
  • Balancing the GTN Bubble with Market Access Priorities
  • What’s Happening in Retail—Brick and Morter, Home Delivery and Cash Pay Pharmacies
  • Navigating Post Deadline Challenges—DSCSA Compliance and Serialization Updates
  • Four Roundtable Breakout Discussions:
    • What Good Looks Like in a 3PL/Manufacturer Partnership
    • Optimizing Healthcare Partnerships
    • Women in Trade
    • GLP-1s and New Product Archetypes
  • Actions Needed to Mitigate and Prevent Drug Shortages
  • Case Study: Master Your Organization Chart—Ensuring Higher Cross Functional Interactions
  • Three Interactive Workshops:
    • Trade 101
    • Advanced Trade Leaders Executive Session
    • Health Systems Fundamentals
  • And more!
Exclusive Offer—Download the agenda and register today—Be sure to use your exclusive promo 24DC10 to save 10% off* of your registration.

See you there!

* Cannot be combined with other offers, promotions or applied to an existing registration. Other restrictions may apply.


The content of Sponsored Posts does not necessarily reflect the views of HMP Omnimedia, LLC, Drug Channels Institute, its parent company, or any of its employees. To find out how you can promote an event on Drug Channels, please contact Paula Fein (paula@DrugChannels.net).
       




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Science Meets Strategy at DIA 2024

Prepare to witness the convergence of strategy and science at the highly anticipated the DIA 2024 Global Annual Meeting! Immerse yourself in four days of conversations that don’t happen anywhere else, where strategic thinking seamlessly intertwines with scientific innovation: Elevate Your Professional Profile Expand your knowledge base with continuing education opportunities available virtually from June […]

The post Science Meets Strategy at DIA 2024 first appeared on ACRO.




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Sequestration Has Less Impact on FDA? Just Not True

“The Hill” newspaper recently reported that: “a survey of federal budgets devoted to developing and enforcing regulations found that many agencies will spend more in 2013 and 2014 than in previous years, indicating that the writing and enforcing of new regulations is largely unimpeded by the massive cuts, known as sequestration.” That certainly sounds authoritative…until you look at the analysis. In fact, the report’s authors appear to know nothing about the federal budget and have used inherently unreliable data in calculating FY 13 and FY 14 spending levels. One can only hope that the authors—allegedly academic experts--know more about regulatory policy than they do about federal budgets.




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Regulatory update for post-registration of biological products in Brazil

<p>On 3<sup>&nbsp;</sup>June 2024,&nbsp;Resolution&nbsp;RDC No. 876 was published in Brazil in the Official Journal of the Union (DOU)[1],&nbsp;modifying the current regulations regarding the post-registration of biological products (RDC 413/2020).</p>




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Regulator looking at 'flexibility' that would allow overseas candidates to sit registration assessment

The General Pharmaceutical Council has said it is “double, treble, quadruple-checking” for any “flexibility” that would allow all overseas candidates to sit the March 2021 registration assessment exam in their countries of residence.




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Overseas candidates will be allowed to sit registration assessment remotely, regulator says

The General Pharmaceutical Council has said most candidates living in countries with a two-hour or more time difference from the UK will be able to apply to sit the registration assessment at home.




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Pharmacy negotiators discuss patient registration with community pharmacies

Pharmacy negotiators have discussed proposals to take “a patient registration-based approach” to the community pharmacy contractual framework.




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Inside Providence’s Health Equity & Medicaid Strategy

Whitney Haggerson — vice president of health equity and Medicaid at Providence — discussed the significance of her role, as well as how her health system is working to give all employees, regardless of title, the skills needed to help reduce health inequities.

The post Inside Providence’s Health Equity & Medicaid Strategy appeared first on MedCity News.




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Biden Administration Should Prioritize Fight Against Superbugs

The Pew Charitable Trusts joined dozens of research, health care, and nonprofit stakeholders in urging President-elect Joe Biden to prioritize and strengthen the national response to antibiotic resistance.




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Registration for SAS Global Forum 2015 is now open

Act now for the best deal on SAS Global Forum 2016 registration. You already know that SAS Global Forum will pay for itself in learning opportunities.




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Tips and Strategies for Mixed Modeling with SAS/STAT Procedures

This paper provides recommendations for circumventing memory problems and reducing execution times for your mixed-modeling analyses, as well as showing the new HPMIXED procedure can be beneficial for certain situations, as with large sparse mixed models.




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236981: U.S. Tauscher engages Rao in strategic security dialogue

While each side adhered to familiar positions, the chemistry between the principals was good and the dialogue was cordial and frank.




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Education, Research, and Innovation in Africa: Forging Strategic Linkages for Economic Transformation

Africa is a youthful continent: nearly 41% of its population is under the age of 18. To address the unique challenges of this demographic structure, the African Union (AU) hopes to reposition the continent as a strategic player in the global economy through improved education and application of science and technology in development. The paper proposes the creation of “Innovation Universities” that combine research, teaching, community service and commercialization in their missions and operations. They would depart from the common practice where teaching is carried out in universities that do little research, and where research is done in national research institutes that do not undertake teaching. Under this model, there is little connection with productive sectors. The idea therefore is not just to create linkages between those activities but to pursue them in a coordinated way under the same university structure. Innovation universities can be created in diverse fields such as agriculture, health, industry, services, and environment to advance sustainable development and inclusive growth.




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Rebooting African Development: Science, Technology and Innovation Strategy for Africa

As the African Union develops its long-term agenda 2063 for the continent, science, technology and innovation will play a bigger part in development goal setting, especially in the context of social and economic growth.




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From the Frontlines to the Future: Assessing Emerging Technology in Russia's Invasion Strategy and NATO's Next Moves

This piece is a series in the Defense, Emerging Technology, and Strategy (DETS) Program’s analysis on the war in Ukraine, including a corresponding policy brief on Ukraine’s Battlefield Technologies and Lessons for the U.S. published in July 2023. 




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Unraveling the Political Dynamics Shaping the U.S. Strategy for Technology Leadership

Although there is broad agreement between the two major parties on the desirability of technology leadership, significant sources of tension—and confusion—persist. By examining the political dynamics that led to the enactment of the CHIPS and Science Act, Constanza M. Vidal Bustamante and Douglass Vijay Calidas probe these tensions and seek to assess their likely impact on the federal technology strategy in the coming years.




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Database on U.S. Department of Energy Budgets for Energy Research, Development, and Demonstration (1978–2025R)

The July 2024 update to our database on the U.S. government investments in energy research, development, demonstration, and deployment (ERD3) through the U.S. Department of Energy.




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The Other Side of the Strait: The Strategic Significance of the Houthi’s Aggression for East Africa

Iranian-backed militants in Yemen are clashing with the United States and British naval forces in the Red Sea over Israel’s operations in Gaza, all in a complex dance for geopolitical leverage in the Middle East. Yet, there is another region with a stake in the conflict brewing in the Bab al-Mandab strait, one seemingly beyond the world’s purview – the Horn of Africa.




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To Enhance National Security, the Biden Administration Will Have to Trim an Exorbitant Defense Wish List

David Kearn argues that even in the absence of restrictive resource and budgetary constraints, a focus on identifying and achieving concrete objectives that will position the United States and its allies to effectively deter aggression in critical regional flashpoints should be the priority given the stressed nature of the defense industrial base and the nuclear enterprise.




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Strategic Myopia: The Proposed First Use of Tactical Nuclear Weapons to Defend Taiwan

David Kearn argues that the idea that the first use of nuclear weapons since 1945 would be by the United States in the defense of Taiwan against a conventional Chinese invasion would have significant, negative, and long-lasting, diplomatic ramifications. It is difficult to fathom the myriad potential consequences, but U.S. nuclear weapon use would almost certainly shatter the non-proliferation regime as a functioning entity, incentivize states (including China) to acquire or improve their existing nuclear arsenal, and damage America's standing globally.




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Is Iran's Strategic Patience at an End?

Assaf Zoran examines the dynamics of Iran's shift from operating in the shadows or behind partners and proxies to directly attacking Israel and Pakistan.

 




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Reflecting on the U.S. Strategy Towards Africa: Embracing Partnership & Pragmatism

The Africa in Focus series is a forum for the intellectual and critical analysis of processes and policies from the continent and its engagement with the international community. Through thoughtful and dynamic programming, Africa in Focus brings greater African perspectives into broader policy conversations at HKS.




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Leveraging Charging Strategies to Reduce Grid Impacts of Electric Vehicles

Electric vehicles (EVs) can challenge or support electricity systems depending on how they are charged. Controlled charging that combines technical solutions with heterogenous EV user behaviors can reduce peak demand to avoid grid constraints and support the integration of renewable energy.




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Harvard Project Director Robert Stavins Moderates Climate Action Week Panel on “Strategies for Mitigating Global Methane Emissions”

Efforts to measure and mitigate the impact of methane emissions was the topic of discussion last Monday (June 10, 2024) at a panel convened as part of Climate Action Week in the Northwest Building, sponsored by Harvard’s Salata Institute for Climate and Sustainability and moderated by Harvard Environmental Economics Program and Harvard Project Director Robert Stavins.




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Institutional investors' shifting allocation strategies are driving hedge funds towards new products - EY�s Natalie Deak on how hedge fund managers are pursuing growth

EY�s Natalie Deak on how hedge fund managers are pursuing growth






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Stratosphere Casino, Hotel & Tower Wants You to "Take Vegas Back" and Receive Random Acts of Rewards - Stratosphere on mixologists

Stratosphere is taking Vegas back from the pricey and pretentious. From the casino to the top of the Tower, Stratosphere offers great fun and real values backed up by an unforgettable experience.





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Grime To Shine Power Tour Lets Customers Demo Pressure Washer Cleaning Systems At Local Lowe's Stores, Sponsored By Briggs & Stratton - Briggs POWERflow+ Pressure Washer

Power washing is made even easier with POWERflow+ Technology by Briggs & Stratton. This pressure washer allows you to do deep cleaning, remove mold and mildew and reach second stories.





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NEW DATA EVALUATING THE BOSTON SCIENTIFIC ELUVIA� DRUG-ELUTING VASCULAR STENT SYSTEM DEMONSTRATE 94.4 PERCENT PRIMARY PATENCY RATE AT NINE MONTHS - Hear from Professor Stefan M�ller-H�lsbeck, M.D., PhD, M

Hear from Professor Stefan M�ller-H�lsbeck, M.D., PhD, MAJESTIC trial principal investigator




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Strategic Partners, Inc. Launches New Medical Apparel Line with CERTAINTY� Antimicrobial Technology - CERTAINTY� Video

Strategic Partners, Inc. has created the next generation of medical apparel using the leading antimicrobial technology of CERTAINTY�.





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VolitionRx Demonstrates NuQ® Blood Test Detects 95% of Pancreatic Cancers in Second Preliminary Study - Introduction to VolitionRx Nucleosomics� technology: Revolutionizing cancer diagnosis

VolitionRx�s Nucleosomics� diagnostic platform detects epigenetic changes to fragments of chromosomes, called nucleosomes, that circulate in the blood of cancer patients. Credit: VolitionRx.




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Gout & Uric Acid Education Society Hosts Roundtable Exploring Strategies for Elevating the Severity of Gout and Improving Access to Public Education and Treatment - Gout as a Serious Health Issue

Gout as a Serious Health Issue