The entertainment curator at the American History Museum shows cinematic highlights from the museum's collections, including Dorothy's red slippers and Superman's cape (Produced by: Ryan Reed). Read more at http://www.smithsonianmag.com/arts-culture/Night-at-the-Museum.html

Interpretive exhibits coordinator Steven Madewells demonstrates a few experiments at Spark!Lab, an interactive exhibit at the National Museum of American History. Read more at: https://www.smithsonianmag.com/smithsonian-institution/theres-nothing-like-a-sparklab-to-ignite-the-imagination-1-180949007/

Learn how to stage a sit-in right next to the Greensboro lunch counter, the location of one of the civil rights movement's most famous protests (Video by: Katy June-Friesen). Read more at http://www.smithsonianmag.com/arts-culture/Courage-at-the-Greensboro-Lunch-Counter.html

The team at the Ol Pejeta Conservancy needs to transport Kinani, a blind male elephant, to a 4,000-acre compound where he'll be able to roam freely without disturbing other wildlife. Weighing in at nearly eight tons, it'll take careful maneuvering and custom equipment to bring the animal to his new sanctuary.

Scientists sent bioengineered heart tissue samples to the ISS to study how to keep astronauts safe during future long-term space travel

The public tours of the historic residence hadn't been overhauled in decades. For two years, the first lady's office has been working to make them more interactive and educational

The team traveled from New Zealand to Tonga along a humpback highway to collect environmental DNA and raise awareness of the plight of the marine mammals

Genetically encoded calcium indicators (GECIs) allow for the noninvasive evaluation of neuronal activity in vivo, and imaging GECIs in Drosophila has become commonplace for understanding neural functions and connectivity in this system. GECIs can also be used as read-outs for studying sleep in this model organism. Here, we describe a methodology for tracking the activity of neurons in the fly brain using a two-photon (2p) microscopy system. This method can be adapted to perform functional studies of neural activity in Drosophila under both spontaneous and evoked conditions, as well as during spontaneous or induced sleep. We first describe a tethering and surgical procedure that allows survival under the microscopy conditions required for long-term recordings. We then outline the steps and reagents required for optogenetic activation of sleep-promoting neurons while simultaneously recording neural activity from the fly brain. We also describe the procedure for recording from two different locations—namely, the top of the head (e.g., to record mushroom body calyx activity) or the back of the head (e.g., to record central complex activity). We also provide different strategies for recording from GECIs confined to the cell body versus the entire neuron. Finally, we describe the steps required for analyzing the multidimensional data that can be acquired. In all, this protocol shows how to perform calcium imaging experiments in tethered flies, with a focus on acquiring spontaneous and induced sleep data.

In insects, oocyte resorption (oosorption) or follicular atresia is one of the key physiological processes and evolutionary strategies used to optimize reproductive fitness. Mosquitoes are ideal model organisms for studying egg maturation in arthropods, as their follicle development is initiated only following the ingestion of a blood meal, followed by a carefully orchestrated series of hormonally regulated events leading to egg maturation. A cohort of approximately 100 follicles per mosquito ovary begin developing synchronously. However, a significant fraction of follicles ultimately undergo apoptosis and oosorption, especially when available resources from the blood meal are limited. Therefore, simple, rapid, and reliable techniques to accurately evaluate follicular atresia are necessary to understand mechanisms underlying follicle development in insects. This protocol describes how to detect apoptotic follicle cells within the Aedes aegypti mosquito ovaries using a commercially available fluorescent-labeled inhibitor of caspases (FLICA). Caspases are key players in animal apoptosis. In this assay, the FLICA reagent enters the intracellular compartment of follicles in dissected mosquito ovaries and covalently binds to active caspases. The bound reagent remains within the cell and its fluorescent signal can be observed by confocal microscopy. Although this method was specifically developed for visualizing apoptotic ovarian follicles during Ae. aegypti mosquito egg development, it should be applicable to other mosquito tissues that undergo caspase-mediated program cell death in a time-dependent manner.

Even as they fundraise for other community organizations, some legions across Canada are having trouble keeping their own lights on amid rising inflation and maintenance costs.

A retired lawyer from Sault Ste. Marie has written a book that celebrates the working-class neighbourhood in which he grew up. The West End: A Magical Place Created by Giants is by Frank Sarlo, whose grandfather emigrated to Chicago from Italy, but ended up in Sault Ste. Marie with the promise of work on the railroad.

A Saskatoon woman is accused of damaging multiple vehicles and assaulting a man with a baseball bat on Nov. 11.

Sleep is likely a whole-brain phenomenon, with most of the brain probably benefiting from this state of decreased arousal. Recent advances in our understanding of some potential sleep functions, such as metabolite clearance and synaptic homeostasis, make it evident why the whole brain is likely impacted by sleep: All neurons have synapses, and all neurons produce waste metabolites. Sleep experiments in the fly Drosophila melanogaster suggest that diverse sleep functions appear to be conserved across all animals. Studies of brain activity during sleep in humans typically involve multidimensional data sets, such as those acquired by electroencephalograms (EEGs) or functional magnetic resonance imaging (fMRI), and these whole-brain read-outs often reveal important qualities of different sleep stages, such as changes in frequency dynamics or connectivity. Recently, various techniques have been developed that allow for the recording of neural activity simultaneously across multiple regions of the fly brain. These whole-brain-recording approaches will be important for better understanding sleep physiology and function, as they provide a more comprehensive view of neural dynamics during sleep and wake in a relevant model system. Here, we present a brief summary of some of the findings derived from sleep activity recording studies in sleeping Drosophila flies and discuss the value of electrophysiological versus calcium imaging techniques. Although these involve very different preparations, they both highlight the value of multidimensional data for studying sleep in this model system, like the use of both EEG and fMRI in humans.

Solutions Catch Problems Early and Drive Cost Out of Designs

Sharing Information Between Design and Production Eliminates Budget Overruns That Erode Customers’ Profits

Ramac Analyzes Design With SolidWorks SustainabilityXpress, Finds Alternatives That Consume Fewer Resources

Young Mexicans are challenged to do their part in missions during a conference in August, in which OM participated.

OM EAST offers a special start to the new school term for hundreds of children in Bosnia-Herzegovina.

Labeling whiteness as "weak" does not reflect the racial terror people of color feel, writes Bettina L. Love.

Are you worried your kids are doomed to be permanently damaged by chronic stress from the pandemic? Take heart from this counselor's advice.

Medical imaging is no longer in Kansas, Toto, as a team led by Penn State researchers brings traditional black and white diagnostic images of X-rays and traditional CT scans into technicolor. The researchers developed novel contrast agents that target two proteins implicated in osteoarthritis, a degenerative joint disease commonly characterized as wear-and-tear arthritis.

Penn State Greater Allegheny’s fourth annual All Campus Day introduced the "Growing Older" common intellectual experience, aimed at exploring and understanding the complexities of aging, especially in a region with a significant senior population.

The Berks LaunchBox recently announced seven recipients of the second round of the “IMAGINE Your Business” grants.

Nathan Levenson of District Management Group discusses how school leaders can improve the quality of special education even as they manage its cost.

Enacting sustainability practices continues to be a key initiative for organizations, according to a new report from the Penn State Arthur W. Page Center for Integrity in Public Communication. The report reveal ways companies can build stronger, more authentic connections with audiences by taking control of their sustainability messaging to shape effective strategies and drive behavior change across all levels of business.

A workshop by the OM team in Córdoba, Argentina gave 25 women new insights on coping with poverty and domestic violence.

Outdoor exploration allows children to have fun while making sense of the world around them and developing their critical-thinking skills.

Leaders from OM Latin America discuss the challenges and opportunities of ministry in the region during their annual meetings in September.

OM Chile's Intensive Training participants travel around the south of Chile for two weeks sharing the gospel, encouraging local churches and doing adventure activities.

NASA’s Power to Explore Challenge calls on U.S. students to submit ideas for moon missions powered by radioisotope systems. The contest encourages kindergarten through Year 12 students to envision a mission, detail objectives, and apply their unique “power” to achieve mission success. Entries are due by January 31, 2025, and grand prize winners will tour NASA’s Glenn Research Center, gaining insight into the technology and science of space exploration.

Honor Magic 7 RSR Porsche Design will join the Honor Magic 7 series soon. As we await the formal launch of the handset, its key specifications have surfaced online. The Honor Magic 7 RSR Porsche Design is tipped to feature a 6.8-inch display with 1.5K resolution and a triple rear camera unit comprising a 200-megapixel periscope telephoto sensor.

All babies born at Bayhealth to receive first Imagination Library book WILMINGTON, Del.— Governor John Carney and the Delaware Division of Libraries announced on Wednesday that Bayhealth has partnered with Dover and Milford Public Libraries to ensure all babies born at Bayhealth Hospitals, as well as any eligible patients of Bayhealth Pediatrics in Milford, are […]

The Delaware Division of the Arts’ Mezzanine Gallery presents artist Colleen Zufelt’s exhibition, Recycle, Repurpose…RE-IMAGINE, showing March 4 through 25, 2022. Her exhibit will also be part of Art Loop Wilmington — the monthly self-guided tour of art in and around the city.

Since the public announcement of Dolly’s arrival in Delaware last week, more than 1,000 Delaware children have been signed up for the Imagination Library. As of last week, over 21,000 Delaware children are enrolled in the program.

Members of the Delaware Nutrient Management Commission approved an emergency order during their October 4 meeting to allow for a 180-day extension for properly staged poultry litter in Delaware Crop fields beginning on November 1.

DOVER, DE (March 11, 2022) – The Delaware Division of Public Health (DPH) Contact Tracing Team has launched a pre-call SMS/text messaging initiative to individuals who test positive for COVID-19. It involves sending a text message to COVID-positive individuals and providing initial isolation guidance and recommendations through a secure web platform before they receive a call from […]

NEW CASTLE (Oct. 10, 2022) – As part of its strategic plan to make access to services easier for Delawareans across the state, the Department of Health and Social Services (DHSS) will begin a critical community engagement phase in which the public can weigh in on the kinds of changes they want to see. For […]

NEW CASTLE (Oct. 10, 2022) – Como parte de su plan estratégico para facilitar el acceso a los servicios para los residentes de Delaware a través del estado, el Departamento de Salud y Servicios Sociales (DHSS) comenzará una fase crítica de participación comunitaria en la que el público puede opinar sobre los tipos de cambios […]

Wilmington, Del. (August 3, 2023) – The Delaware Division of the Arts recently secured new funding from a national grant program to advance creative aging programs for adults aged 55+ in Delaware. Building upon the transformative success of the Leveraging State Investments in Creative Aging program, which catalyzed arts learning opportunities for adults aged 55+ […]

NEW CASTLE – The Delaware Department of Health and Social Services (DHSS) announced today enhancements to the CostAware website, designed to help Delawareans understand how their health care dollars are spent by comparing the variation of average costs for different episodes of care and medical services based on actual medical and pharmacy claims in Delaware. […]

NEWARK – The Delaware Department of Health and Social Services’ Division of Services for Aging and Adults with Physical Disabilities (DSAAPD) will seek public comment on its proposed State Plan on Aging for the period of October 2024 through September 2028. The State Plan has been developed to meet requirements under Title III and Title […]

SAS SVP Kimberly May provides an update about the new Support Operating Model.

Improving Our Agility was published on SAS Users.

WILMINGTON, Del. – Governor John Carney, First Spouse Tracey Quillen Carney, and the Delaware Libraries on Monday announced that a bilingual English/Spanish book collection option will soon be available for Delaware families. “There is nothing more important than ensuring our children learn to read by third grade so they can read to learn for the rest […]

[SAPS] - Five suspects are appearing in the Kariega Magistrate's Court today, after they were arrested and found in possession of cycads with an estimated value of R1 Million on Friday 08 November 2024.

We live in a rapidly growing “digitalized world,” with an ever-increasing need for video/music streaming, gaming, AI/machine learning, etc. All of these propel demand on modern SoC design to quickly evolve the SoC by fitting more sophisti...(read more)

The silkscreen layer plays a crucial role in the assembly, repair, and testing of a PCB. You can add a variety of information to this layer, such as the location of the components, polarity, component orientation, on-off switches, LEDs, and testpoint...(read more)

A constraint is a user-defined property, or a rule, applied to a physical object, such as a net, pin, or via in a design. There are a number of constraints that can be applied to an object based on its type and behavior. For example, you can define t...(read more)

In the era of Artificial Intelligence, front-end designers need a magical key to empower them with technology that enables fully optimized RTL for implementation handoff and provides RTL designers with capabilities to accurately assist in the implementation convergence process.

The magic lies with Cadence Joules RTL Design Studio, an expert system that leverages generative AI for RTL design exploration, triages possible causes of violations, and additional insights that empower designers to understand how to address issues in their RTL, leading to smarter and more efficient chip design.

This unlocks the immense debugging and design analysis capabilities from a single, unified cockpit, enabling fully optimized RTL design prior to implementation handoff for the front-end designers and addresses all aspects of physical design by adding visibility into power, performance, area, and congestion (PPAC)

One critical component is the clock tree, which distributes the clock signal to all sequential elements, such as flip-flops and latches. Designers need the right techniques in the beginning stage to optimize the clock tree structure, ensuring that their designs meet the required timing specifications, reduce power consumption, maintain signal integrity, and increase reliability.

 This incredible feature is part of the Joules RTL Design Studio.

How do you efficiently explore the clock tree structure to optimize the results using Joules RTL Design Studio?

Joules Studio allows viewing a simplified version of the clock structure. This feature is primarily designed to help display clock frequency scaling through clock dividers. You can customize colors, symbols, and design elements using an input file. Additionally, you can cross-probe the custom clock tree structure to other widgets and the main schematic view in Joules Studio.

Moreover, with the clock tree preference features of the ideal clock tree wizard in Joules Studio GUI, you can highlight clock path, generate clocks and master clock, set case analysis, fold and unfold instances, undo and redo, set sense and disable timing, color preference, etc.

You can binge on these features through the channel videos posted on the support portal, which covers the Joules RTL Design Studio GUI Clock Tree Structure and Features of Ideal Clock Tree Wizard.

You can refer to the videos on Cadence Online Support (Cadence login required).

​Video Links:
Viewing Custom Clock Tree Structure in Joules RTL Design Studio (Video) 

Exploring Clock Tree Preference Widget of Ideal Clock Tree Wizard in Joules RTL Design Studio (Video) 

Want to learn more?

Explore the one-stop solution Joules RTL Design Studio Product Page on Cadence Online Support (Cadence login required).

Related Resources 

Related Training Bytes:

Understanding Prototype Design Flow in Joules RTL Design Studio (Video)

Running Prototype Implementation Flow in Joules RTL Design Studio (Video)

Understanding Analyze Timing By Hierarchy In Joules RTL Design Studio (Video)

Related Courses:

• Joules Power Calculator

Want to Enroll in this Course?

We organize this training for you as a "Blended" or "Live" training. Please reach out to Cadence Training for further information.

Please don't forget to obtain your Digital Badge after completing the training.

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Let's Discover the Secret to Enhance Design's PPAC in a Single Cockpit! - Digital Design - Cadence Blogs - Cadence Community

Joules RTL Design Studio: Accelerating Fully Optimized RTL - Digital Design - Cadence Blogs - Cadence Community

Let's Replay the Process of Power Estimation with the Power of 'x'! - Digital Design - Cadence Blogs - Cadence Community

Is Design Power Estimation Lowering Your Power? Delegate and Relax! - Digital Design - Cadence Blogs - Cadence Community