PURPOSE

We undertook a trial to test the efficacy of a technology-assisted health coaching intervention for weight management, called Goals for Eating and Moving (GEM), within primary care.

Approximately 8.5%–16.2% of childhood cancers are associated with a pathogenic/likely pathogenic germline variant—a prevalence that is likely to rise with improvements in phenotype recognition, sequencing, and variant validation. One highly informative, classical hereditary cancer predisposition syndrome is Li–Fraumeni syndrome (LFS), associated with germline variants in the TP53 tumor suppressor gene, and a >90% cumulative lifetime cancer risk. In seeking to improve outcomes for young LFS patients, we must improve the specificity and sensitivity of existing cancer surveillance programs and explore how to complement early detection strategies with pharmacology-based risk-reduction interventions. Here, we describe novel precision screening technologies and clinical strategies for cancer risk reduction. In particular, we summarize the biomarkers for early diagnosis and risk stratification of LFS patients from birth, noninvasive and machine learning–based cancer screening, and drugs that have shown the potential to be repurposed for cancer prevention.

Background

In an evolving landscape of practices and policies, reviewing and incorporating the latest scientific evidence is necessary to ensure optimal clinical management for people with opioid use disorder. We provide a synopsis of the 2024 update of the 2018 National Guideline for the Clinical Management of Opioid Use Disorder, from the Canadian Research Initiative in Substance Matters.

Central sleep apnoea (CSA) is characterised by recurrent episodes of airway cessation or reduction in the absence of respiratory effort. Although CSA is less common than obstructive sleep apnoea, it shares similar symptoms. CSA can be secondary to various medical conditions, high altitude and medication exposure. CSA can also emerge during obstructive sleep apnoea therapy. There are a range of treatment options and selecting the right therapy requires an understanding of the pathophysiology of CSA. This review explores the aetiology, pathophysiology and clinical management of non-hypercapnic CSA.

Chronic pulmonary aspergillosis has a range of manifestations from indolent nodules to semi-invasive infection. Patients may be asymptomatic or have chronic symptoms such as cough and weight loss or present with life-threatening haemoptysis. The physician can choose from a range of available therapies including medical therapy with antifungals, minimally invasive therapy with intracavitary antifungal therapy and surgery involving open thoracotomy or video-assisted thoracoscopic surgery. The patients with the most severe forms of pulmonary infection may not be surgical candidates due to their underlying pulmonary condition. The management of haemoptysis can include tranexamic acid, bronchial artery embolisation, antifungals or surgery. There are few controlled studies to inform clinicians managing complex cases, so a multidisciplinary approach may be helpful.

Palliative care pertains to the holistic multidimensional concept of "patient-centred" care. It is an interprofessional specialty, primarily aiming to improve quality of care for cancer patients and their families, from the time of diagnosis of malignant disease, over the continuum of cancer care, and extending after the patient's death to the period of bereavement to support the patient's family. There are various complex and frequently unmet needs of lung cancer patients and their families/caregivers, not only physical but also psychological, social, spiritual and cultural. Systematic monitoring of patients’ symptoms using validated questionnaires and patient-reported outcomes (PROs), on a regular basis, is highly encouraged and recommended in recent guidelines on the role of PRO measures in the continuum of cancer clinical care. It improves patient–physician communication, physician awareness of symptoms, symptom control, patient satisfaction, health-related quality of life and cost-effectiveness. This implies that all treating physicians should improve their skills in communication with lung cancer patients/relatives and become more familiar with this multidimensional assessment, repeatedly screening patients for palliative care needs. Therefore, they should receive education and training to develop palliative care knowledge, skills and attitudes. This review is dedicated to lung cancer palliative care essentials that should be within the competences of treating physicians, i.e. pneumologists/thoracic oncologists.

In today’s complex business environment, organizations rely heavily on external vendors for essential services and resources. Managing these relationships effectively is crucial for operational efficiency, cost control, and risk management. To achieve this, many companies turn to Vendor Management Software to streamline vendor interactions, ensuring that the right processes and tools are in place for […]

The post Optimizing Vendor Portfolio with Vendor Management Software appeared first on Chart Attack.

Getting outside – without your phone – is one way to disconnect.

The province says the move comes "after years of AIMCo consistently failing to meet its mandated benchmark returns." For now, Finance Minister Nate Horner has been appointed the AIMCo board's sole director and chair. Senior public servant Ray Gilmour has been appointed interim CEO.

Outside groups often offer their solutions for climate adaptation in Africa. But the best people to manage the climate crisis are the people in those communities themselves. For climate adaptation to succeed in Africa, let communities and local leaders show the way

Charco Neurotech, a medtech company based in the United Kingdom, has developed CUE1, a non-invasive wearable that is intended to assist those with Parkinson’s disease to manage their motor symptoms. The device is typically affixed to the sternum, and provides vibratory action in a focused region of the body. The technology is based on the […]

This week, I’m rerunning some popular posts while we put the finishing touches on DCI’s new 2024-25 Economic Report on Pharmaceutical Wholesalers and Specialty Distributors.

Click here to see the original post from June 2024.

Hospitals across the U.S. have significantly restricted the use of pain medications containing narcotics. This shift comes amid […]

EY�s Natalie Deak on how hedge fund managers are pursuing growth

2015 Sodexo Workplace Trends Overview

Complete Tax Forms Fast, Easy, And Secure For Taxpayers And Accountants

Build your career � the MYRA way

Gaining Independence While Living with Diabetes

Aspen Dental & Danica Patrick unveil a salute to more than 2,200 veterans at Chicagoland Speedway to honor their service and raise awareness about the need for oral health care.

Simple steps for Alzheimer's planning.

Download CA Intermediate Cost and Management Accounting Question Papers New Course Sep 2024 in PDF. For other question papers of CA Inter May 2024, Nov 2023, May 2023, Nov 2022, May 2022, Dec 2021, July 2021, Nov 2020, Nov 2019, May 2019, Nov 18, May 2018, Nov 2017, Nov 2016, May 2016, May 17, may 2016, CA IPC Nov 2015, CA IPC may 2015, CA IPC Nov 2014 check similar section. Previous years Taxation CA IPCC IPC question papers can also be downloaded using Search. You can also search and download may 2015 Final question papers here. We are providing ca final question papers of may 2016 for Financial Reporting FR, Advanced Financial Management AFM, Advanced Auditing and Professional Ethics, Taxation, Corporate & Allied Laws,Advanced & Management Accounting AMA, Direct Tax Laws DT, Indirect Tax Laws IDT and IPCC/IPC may 2015 question papers for Advanced Accounting , Business, Law, Ethics & Communications, Taxation, Advanced Accounting , Auditing & Assurance, Information Technology & Strategic Management ITSM.

Download CA Intermediate Financial Management and Strategic Management Question Papers New Course Sep 2024 in PDF. For other question papers of CA Inter May 2024, Nov 2023, May 2023, Nov 2022, May 2022, Dec 2021, July 2021, Nov 2020, Nov 2019, May 2019, Nov 18, May 2018, Nov 2017, Nov 2016, May 2016, May 17, may 2016, CA IPC Nov 2015, CA IPC may 2015, CA IPC Nov 2014 check similar section. Previous years Taxation CA IPCC IPC question papers can also be downloaded using Search. You can also search and download may 2015 Final question papers here. We are providing ca final question papers of may 2016 for Financial Reporting FR, Advanced Financial Management AFM, Advanced Auditing and Professional Ethics, Taxation, Corporate & Allied Laws,Advanced & Management Accounting AMA, Direct Tax Laws DT, Indirect Tax Laws IDT and IPCC/IPC may 2015 question papers for Advanced Accounting , Business, Law, Ethics & Communications, Taxation, Advanced Accounting , Auditing & Assurance, Information Technology & Strategic Management ITSM.

Download CA Final Advanced Financial Management (AFM) Question Papers New Course Nov 2024 in PDF. For older question papers of CA final May 2024, Nov 2023, May 2023, Nov 2022, May 2022, Dec 2021, Nov 2020, May 2019, Nov 2018,CA final May 2018, Nov 2017, May 2017, CA final may 2016, CA final Nov 2016 check similar section. Previous years CA final Financial Reporting FR question papers can also be downloaded using Search. You can also search and download may 2015 IPCC & IPC question papers here. We are providing ca final question papers of may 2016 for Financial Reporting FR, Advanced Financial Management AFM, Advanced Auditing and Professional Ethics, Direct Tax Laws DT, Indirect Tax Laws IDT,Integrated Business Solutions (Multidisciplinary Case Study with Strategic Management) and IPCC/IPC Nov 2023 question papers for Accounting, Business, Law, Ethics & Communications , Cost Accounting & Financial Management CAFM, Taxation, Advanced Accounting , Auditing & Assurance, Information Technology & Strategic Management ITSM.

Renowned singer Chappell Roan has stirred discussions among her fans after she commented on Billboard’s post that stated that she has parted ways with her management team and manager, Nick Bobetsky. She recently made headlines after her name was inducted into the list of candidates who are nominated in the big categories of next year’s […]

The post Why Fans Think Chappell Roan Has Fired Her Manager Nick Bobetsky appeared first on ComingSoon.net - Movie Trailers, TV & Streaming News, and More.

The AAR Maharashtra, in the case of M/s. The Nisarga Consultancy, In Re [Order No. GST-ARA-21 of 2023-24/2024-25/B-55 dated July 31, 2024] ruled that no tax will be leviable on work allotted by Maharashtra Jeevan Pradhikar ("MJP") as per of Jal Jeevan Mission ("JJM") which is a mission of Government

Highlights: Curcumin in turmeric aids weight loss and reduces inflammation It shows promise in managing o

Warsaw, Poland – November 15th 2013 – Climate change will have a “profound” impact on water resources that could have serious knock-on effects for agriculture, according to a new report published today. Download the full media release

The post Smart water management can help avert climate-induced food shortages first appeared on International Water Management Institute (IWMI).

Colombo, December 10, 2013. At the request of the Colombo Municipal Council (CMC), the Central Environmental Authority (CEA), in collaboration with the International Water Management Institute (IWMI), organized a stakeholder meeting to discuss improvements that can be made to the management of municipal waste in the City of Colombo. The meeting was held at the […]

The post CEA partners with IWMI to improve Colombo’s municipal waste management and farmers’ access to organic fertilizers first appeared on International Water Management Institute (IWMI).

Targets that promote efficient, nationally and locally appropriate water use will be key to achieving the SDGs.

The post Press Release: Sustainable Development Goals Offer Unique Opportunity to Transform Management of Critical Water Resources first appeared on International Water Management Institute (IWMI).

Experts from across Asia gathered to discuss how the next generation of satellite based technologies could help improve disaster preparedness and response at a three-day meeting in Mount Lavinia.

The post Press Release: Satellite imaging and disaster management experts gather in Colombo first appeared on International Water Management Institute (IWMI).

The five Partner States of the Kavango Zambezi Transfrontier Conservation Area (KAZA TFCA) have joined forces with IWMI to manage groundwater resources spanning an area larger than Austria and Germany.

The post New project brings five African countries together to jointly manage region’s groundwater first appeared on International Water Management Institute (IWMI).

Climate change and water resilience a joint priority, as international research organization prepares to launch new strategy and mark 40-year anniversary.

The post IWMI’s new Board Chair and Sri Lanka’s Prime Minister reiterate commitment to sustainable water management first appeared on International Water Management Institute (IWMI).

Ulcerative colitis (UC) is an inflammatory bowel illness that affects the lining of the large intestine, causing irritation, inflammation, and medlinkulcers/medlink.

The Climate Smart Governance (CSG) Dashboard is recognized for its contribution to national climate adaptation, planning and development.

The post IWMI awarded for second consecutive year by the Project Management Institute in Sri Lanka first appeared on International Water Management Institute (IWMI).

The meeting is part of a bottom-up approach to ensuring coherent policies on the use of water resources in agriculture.

The post IWMI conducts grassroots consultation on irrigated groundwater management in Lao PDR first appeared on International Water Management Institute (IWMI).

AGRIS is a comprehensive bibliographic database focused on agriculture and nutrition, while AGROVOC is a multilingual thesaurus covering a wide range of agricultural terms.

The post A conversation with IWMI’s knowledge management team on enhancing agricultural research with FAO’s AGRIS and AGROVOC programs first appeared on International Water Management Institute (IWMI).

Hope tends to be more helpful than mindfulness in assisting people in managing their stress and maintaining their professional engagement during extended

Remote video consultations with medlinkmental health/medlink specialists lead to a small yet meaningful improvement in symptoms of depression and anxiety (!--ref1--).

This training was conducted through the World Bank funded Balochistan Integrated Water Resources Management and Development Project (BIWRMDP).

The post Decision Making On Scientific Data For Improved Water Resource Management Critical: IWMI first appeared on International Water Management Institute (IWMI).

The Economic Community of West African States (ECOWAS) and IWMI seek to work together to address the challenges of water scarcity, climate change, and sustainable irrigational agriculture practices in the region.

The post ECOWAS, IWMI call for efficient water resources management first appeared on International Water Management Institute (IWMI).

Tanusree Paul and Naga Velpuri call for investing in interventions to strengthen women’s capabilities and participation in water governance.

The post Mainstreaming gender in participatory irrigation management: Why does empowerment matter? first appeared on International Water Management Institute (IWMI).

IWMI's Suchiradipta Bhattacharjee comments on how India, the largest user of groundwater globally, can transition from water scarcity to water security.

The post We need a strategy to manage our water first appeared on International Water Management Institute (IWMI).

Low-income Black and Hispanic stroke survivors with uncontrolled hypertension experienced a more than two-fold reduction in systolic medlinkblood pressure/medlink

NCPA Applauds Rep. Weiner for Introducing Bill to Rein in Pharmacy Benefit Manager Practices That Hurt Patients, Plan Sp

Approximately one in five Americans experiences chronic pain, and existing medications aren't very promising. Feixiong Cheng, Ph.D, Director of the Genome

The Indian government has taken a significant step towards improving the health of medlinknewborn babies/medlink by establishing Comprehensive Lactation

Parents and doctors shape how children manage pain later in life by the way they treat pain, whether it's a minor injury or medlinkfear of injections/medlink.