(California Court of Appeal) - Upheld a cleanup and abatement order issued to a utility company, which was found to be a responsible party for pollution in San Diego Bay, nearby which it operated a power plant for many years. Affirmed the denial of the company's petition for writ relief.

(California Court of Appeal) - Affirmed the judgment upholding the Defendant, Water Board’s, determination that Plaintiff was jointly and severally responsible for the cleanup and abatement of petroleum residue or waste. Plaintiff sought a reversal of order denying petition to overturn that determination.

When you upload an image to WordPress it’s processed and compressed to 90% of its original JPEG quality. This is a default setting that’s in place to automatically optimize every…

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From September 2019 Onwards, Audials Generation 2020 Will Be Available On Online Shops And In Specialist Stores.

The Prolific Singer-Songwriter Says The Song Is “For All The Women Who Boldly And Bravely Speak Their Truth”

(United States Ninth Circuit) - Remanding a case in which a Miami retirement trust obtained the stock of a company and later complained of false statements that the district court found to be puffery, forward looking, appropriately cautioned, without knowledge of their falsity, or protected by the safe harbor provision of the Private Securities Litigation Reform Act but the panel found that many of these exceptions did not apply in the given situation.

He posted adorable pictures with his little brother.

Although CEACAM1 (CC1) glycoprotein resides at the interface of immune liver injury and metabolic homeostasis, its role in orthotopic liver transplantation (OLT) remains elusive. We aimed to determine whether/how CEACAM1 signaling may affect hepatic ischemia-reperfusion injury (IRI) and OLT outcomes. In the mouse, donor liver CC1 null mutation augmented IRI-OLT (CC1-KO→WT) by enhancing ROS expression and HMGB1 translocation during cold storage, data supported by in vitro studies where hepatic flush from CC1-deficient livers enhanced macrophage activation in bone marrow–derived macrophage cultures. Although hepatic CC1 deficiency augmented cold stress–triggered ASK1/p-p38 upregulation, adjunctive ASK1 inhibition alleviated IRI and improved OLT survival by suppressing p-p38 upregulation, ROS induction, and HMGB1 translocation (CC1-KO→WT), whereas ASK1 silencing (siRNA) promoted cytoprotection in cold-stressed and damage-prone CC1-deficient hepatocyte cultures. Consistent with mouse data, CEACAM1 expression in 60 human donor liver biopsies correlated negatively with activation of the ASK1/p-p38 axis, whereas low CC1 levels associated with increased ROS and HMGB1 translocation, enhanced innate and adaptive immune responses, and inferior early OLT function. Notably, reduced donor liver CEACAM1 expression was identified as one of the independent predictors for early allograft dysfunction (EAD) in human OLT patients. Thus, as a checkpoint regulator of IR stress and sterile inflammation, CEACAM1 may be considered as a denominator of donor hepatic tissue quality, and a target for therapeutic modulation in OLT recipients.

BACKGROUND Glucose-6-phosphate dehydrogenase (G6PD) deficiency decreases the ability of red blood cells (RBCs) to withstand oxidative stress. Refrigerated storage of RBCs induces oxidative stress. We hypothesized that G6PD-deficient donor RBCs would have inferior storage quality for transfusion as compared with G6PD-normal RBCs.METHODS Male volunteers were screened for G6PD deficiency; 27 control and 10 G6PD-deficient volunteers each donated 1 RBC unit. After 42 days of refrigerated storage, autologous 51-chromium 24-hour posttransfusion RBC recovery (PTR) studies were performed. Metabolomics analyses of these RBC units were also performed.RESULTS The mean 24-hour PTR for G6PD-deficient subjects was 78.5% ± 8.4% (mean ± SD), which was significantly lower than that for G6PD-normal RBCs (85.3% ± 3.2%; P = 0.0009). None of the G6PD-normal volunteers (0/27) and 3 G6PD-deficient volunteers (3/10) had PTR results below 75%, a key FDA acceptability criterion for stored donor RBCs. As expected, fresh G6PD-deficient RBCs demonstrated defects in the oxidative phase of the pentose phosphate pathway. During refrigerated storage, G6PD-deficient RBCs demonstrated increased glycolysis, impaired glutathione homeostasis, and increased purine oxidation, as compared with G6PD-normal RBCs. In addition, there were significant correlations between PTR and specific metabolites in these pathways.CONCLUSION Based on current FDA criteria, RBCs from G6PD-deficient donors would not meet the requirements for storage quality. Metabolomics assessment identified markers of PTR and G6PD deficiency (e.g., pyruvate/lactate ratios), along with potential compensatory pathways that could be leveraged to ameliorate the metabolic needs of G6PD-deficient RBCs.TRIAL REGISTRATION ClinicalTrials.gov NCT04081272.FUNDING The Harold Amos Medical Faculty Development Program, Robert Wood Johnson Foundation grant 71590, the National Blood Foundation, NIH grant UL1 TR000040, the Webb-Waring Early Career Award 2017 by the Boettcher Foundation, and National Heart, Lung, and Blood Institute grants R01HL14644 and R01HL148151.

IBM Research today opened its second research location on the African continent and announced several new project collaborations in the areas of data driven healthcare, digital urban ecosystems and astronomy.

ENGIE, a global leader in energy transition, today announced a new initiative with IBM. This nonexclusive, technological and commercial alliance is designed to improve the management of cities by looking at patterns, event correlation, anomaly detection and real-time data across all parts of cities.

IBM today announced a research collaboratory in Singapore, where researchers from IBM intend to collaborate with scientists and engineers from public agencies in Singapore to improve the quality of its urban services. The focus of this research effort will be to use sensor networks to more effectively model, predict and manage the use of natural and physical infrastructure resources – water, transport and energy.  

IBM's World Community Grid, a worldwide network of PC owners helping scientists solve humanitarian challenges, today announced several computing projects aimed at developing techniques to produce cleaner and safer water, an increasingly scarce commodity eluding at least 1.2 billion people worldwide.

Michael McEwan speaks to Ian Buchanan about Disability Equality Scotland, focusing more specifically on Disability Access Panels.

As the umbrella body for Access Panels in Scotland, Disability Equality Scotland offers support and training opportunities to help Access Panels operate efficiently, link together as a network and learn from each other.

Transcript of episode

Music Credit: Make your dream a reality by Scott Holmes

It's been seven years since we talked about the HPA like this! Learn about how the organization has been changing the world!

It's NOT about those dang tweets, not yet! We will be back soon for those. Right now we are doing a LONG OWED update with the HP Alliance! It's been seven years since we talked about the HPA like this! Seven years! Learn about how the organization has been changing the world, how fans are becoming heroes, and how you can help!

We also talk about Emma Watson at the UN, the future of the Leaky Cauldron and PotterCast...and more! Special host Paul DeGeorge joins in, and we hear from several more members of the HPA!

Episode 255 — Equality FTW!

Find the latest episode and explore PotterCast interviews, discussions and more at PotterCast.com

Visit the-leaky-cauldron.org for the latest and greatest from Harry Potter's Wizard World.

Who’s afraid of a global pandemic? We all are, at the moment. But like so many other forms of fear, concern about medical issues is much more acute for people in precarious and vulnerable social positions. The privileged—particularly those who are white and upper class—can more afford not to be preoccupied with health and medical […]

Embed from Getty Images In the previous essay on charter schools I considered the monopoly argument in their favor. On this view, charter schools break the state’s harmful monopoly on education and this is a good thing. It is worth …

Study shows how a lack of community support caused by inequality exacerbates cycles of poverty

As global climate change leads to more hot and dry weather, the resulting droughts are stressing plants, making them less able to remove ozone — which at ground level is a dangerous pollutant — from the air.

DALLAS – (May 8, 2020) Today, the U.S. Environmental Protection Agency (EPA) is announcing that the Louisiana Department of Environmental Quality will receive $800,000 as a Brownfields revolving loan fund grant.

Ambient pollution is a byproduct of economic activity. It has been widely reported that COVID-19 and associated lockdowns have generated large improvements in air quality worldwide, including to China's notoriously-poor air quality. We analyze China's official pollution monitor data and account for the large, recurrent improvement in air quality following Lunar New Year (LNY), which essentially coincided with lockdowns in 2020. With the important exception of NO2, China's air quality improvements in 2020 are smaller than we should expect near the pandemic's epicenter: Hubei province. Compared with LNY improvements experienced in 2018 and 2019 in Hubei, we see smaller improvements in SO2 while ozone concentrations increased in both relative and absolute terms (roughly doubling). Similar patterns are found for the six provinces neighboring Hubei. We conclude that whether COVID-19 actually decreased pollution in China depends on the pollutant and reference period considered.

We explored two measures of inequality that described the full income distribution in cities. One measure is an income gini based on family incomes in 1929 for 33 cities and in 1933 for up to 48 cities in 1933 were spread throughout the country. We also estimated gini coefficients that made use of contract rents for renters and implicit rents for home owners for up to 955 cities throughout the country. We were able to expand to all counties when looking at a top-end inequality measure, the number of taxpayers per family. All three measures varied substantially across the country. We show the correlations between the various measures and also estimate the relationship between the measures and various relief programs developed by governments at all levels during the period.

This paper investigates the effect of a large negative agricultural shock, the boll weevil, on black-white inequality in the first half of the twentieth century. To do this we use complete count census data to generate a linked sample of fathers and their sons. We find that the boll weevil induced enormous labor market and social disruption as more than half of black and white fathers moved to other counties following the arrival of the weevil. The shock impacted black and white sons differently. We compare sons whose fathers initially resided in the same county and find that white sons born after the boll weevil had similar wages and schooling outcomes to white sons born prior to its arrival. In contrast, black sons born after the boll weevil had significantly higher wages and years of schooling, narrowing the black-white wage and schooling gaps. This decrease appears to have been driven by relative improvements in early life conditions and access to schooling both for sons of black fathers that migrated out of the South and sons of black fathers that stayed in the South.

Estimating the returns to education remains an active area of research amongst applied economists. Most studies that estimate the causal return to education exploit changes in schooling and/or labor laws to generate exogenous differences in education. An implicit assumption is that more time in school may translate into greater earnings potential. None of these studies, however, explicitly consider the quality of schooling to which impacted students are exposed. To extend this literature, we examine the interaction between school quality and policy-induced returns to schooling, using temporally-available school quality measures from Card and Krueger (1992). We find that additional compulsory schooling, via either schooling or labor laws, increases earnings only if educational inputs are of sufficiently high quality. In particular, we find a consistent role for teacher quality, as measured by relative teacher pay across states, in generating consistently positive returns to compulsory schooling.

We construct a quantitative model of an economy hit by an epidemic. People differ by age and skill, and choose occupations and whether to commute to work or work from home, to maximize their income and minimize their fear of infection. Occupations differ by wage, infection risk, and the productivity loss when working from home. By setting the model parameters to replicate the progression of COVID-19 in South Korea and the United Kingdom, we obtain three key results. First, government-imposed lock-downs may not present a clear trade-off between GDP and public health, as commonly believed, even though its immediate effect is to reduce GDP and infections by forcing people to work from home. A premature lifting of the lock-down raises GDP temporarily, but infections rise over the next months to a level at which many people choose to work from home, where they are less productive, driven by the fear of infection. A longer lock-down eventually mitigates the GDP loss as well as flattens the infection curve. Second, if the UK had adopted South Korean policies, its GDP loss and infections would have been substantially smaller both in the short and the long run. This is not because Korea implemented policies sooner, but because aggressive testing and tracking more effectively reduce infections and disrupt the economy less than a blanket lock-down. Finally, low-skill workers and self-employed lose the most from the epidemic and also from the government policies. However, the policy of issuing “visas” to those who have antibodies will disproportionately benefit the low-skilled, by relieving them of the fear of infection and also by allowing them to get back to work.

From a neurobiology perspective, anxiety and sleep deprivation look very much alike.

Rita Walters advocated fiercely for equality through school integration and hiring practices, first as a member of the L.A. school board and then on the L.A. City Council

Chinese companies producing faulty testing kits and masks are marring Beijing's attempts to assert leadership in the fight against the coronavirus.

In one article, wealthy private schools get government aid. In another, desperate citizens beg for funds online.

Filmmaker Justin Pemberton turns French economist Thomas Piketty's 2013 manifesto on inequality, "Capital in the Twenty-First Century," into an engaging documentary.

In the US the protest movement is symbolically against the top 1%. Income data from the US Congressional Budget Office, however, shows that it isn’t just the top 1% benefiting far more than the rest of American society, but the top 0.1% in particular.

High levels of inequality is generally believed to affect social cohesion. Some findings suggest that once nations are industrialized, more equal societies almost always do better in terms of health, well-being and social cohesion and that large income inequalities within societies destroys the social fabric and quality of life for everyone.

This update to the poverty page adds a section on inequality in the US, as well as adding some additional information about research showing globally some 147 multinational companies having core global influence and power.

Read full article: Poverty Around the World

Position Overview: Under the direction of the Engineering Manager, the Design Quality Assurance Engineer (DQE) focuses on the prevention of product flaws and failures throughout the Product Development processes in order to ensure the final product meets all customer and company requirements. The D

THERE'S a little village in Cornwall that's making all the right movies. And it's not Port Isaac, which is rightly famous for ITV's Doc Martin and BBC's period drama Poldark. No, this is Portloe, which can lay claim to being the forerunner when, back in 1949, Disney chose the tiny fishing village to film scenes for its celluloid masterpiece Treasure Island.

Dune HD announces a new partnership with Qarva designed to enhance the IPTV experience. The integration of Qarva’s FastSwitch technology into Dune HD’s digital media players and set-top boxes will give IPTV subscribers improved interaction and higher quality through faster channel changing and the elimination of packet loss. The joint solution will be demonstrated by Dune HD on stand 17 at TV Connect MENA 2012.

An enhanced, high quality experience is proven to increase subscriber loyalty and is central to operators reducing churn and growing revenues. FastSwitch improves the viewing experience by dramatically reducing the lag associated with controlling IPTV services, bringing response times down from 5 seconds to less than half a second - in line with the speeds achieved through traditional TV broadcast channels. Through its integral Packet Loss Recovery technology, FastSwitch also eliminates IPTV issues such as picture freezing and blocking, delivering an improved viewing performance.

Qatar Telecom has selected Mariner's IP video service oriented monitoring solution, Mariner xVu. The latest version of Mariner xVu is specifically designed for integration with IPTV probes. Qtel will use Mariner xVu for the Mozaic TV service, making this the first Mariner xVu deployment in the Middle East.

Alfalak Electronic Equipment & Supplies Co., partnered with Mariner to deploy xVu. Through easy integration with network probes — at the head-end and/or individual network element — Mariner xVu offers Qtel additional insights into the IPTV network by extending video service monitoring reach to each subscriber, allowing the operator to maintain the highest possible video quality while simultaneously reducing operating expenses. Statistics collected by external data sources such as probes are compiled and configured as status indicators on Mariner NetworkVu to enable a deeper understanding of IPTV traffic and customer experience issues. The probe enhancement is now a configurable option of NetworkVu, rather than a custom development, and was created based on service provider requests for integration with external data sources.

strataconf: Big data vs big reality http://t.co/D751jk0ntb Data itself has no quality. It’s what you do with it that counts

You have to invest real time into earning links from high-authority sites by doing your own research and digital public relations.

Please visit Search Engine Land for the full article.

velocityconf: New #velocityconf CA program preview is up: http://t.co/rKjf91RXdD @ariyahidayat on End-to-End JS Quality Analysis.

“Outbreaks have sparked riots and propelled public-health innovations, prefigured revolutions and redrawn maps.” – The New Yorker, April 2020 “Nothing will be the same.”  That’s the overwhelming takeaway I’ve heard from dozens of conversations I’ve had with C-suite leaders, physicians, policy experts and media professionals these past few weeks.  When it comes to the business … Continue reading "An Open Letter To American Corporations: It’s Good Business (and Smart Marketing) To Support Quality Journalism"

Research Event

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Research Event

7 May 2020