In the last few years, there has been an increasing focus on the need for adequate ethics guidance for the use of artificial intelligence and robots – something we have regularly written and spoken about. For example, in 2017, MEPs from the E...

One could be forgiven for thinking the UK Government had put its other legislative plans on hold as it seeks to deliver Brexit, but this is not the case. In February we saw the launch of a number of parallel consultations all designed to tackle plas...

In this period of market uncertainty, financial services firms globally are facing a number of challenges and questions. We have created a selection of recent articles, webinars, podcasts and short videos published by Eversheds Sutherland to he...

U.S. Open champion Bianca Andreescu has discovered a powerful tool to compensate for limited training opportunities amid the COVID-19 lockdown as the Canadian teenager remains ...

God’s Word is clear—believers are not to be given over to anxiety. But it’s not simply a cold, abrupt command to stop worrying. Scripture is clear that we shouldn’t focus on the plans, needs, and uncertainties of tomorrow, but it’s also clear about where our focus should be instead.

China’s officials must stay “sober-minded” to handle the variety of coronavirus-related challenges that lie ahead, as mistakes could undermine relations with major developed nations and harm the country’s economic outlook, according to outspoken former Chongqing mayor Huang Qifan.Issues over the origin of the virus, compensation claims by the United States and decoupling worries have all appeared in the wake of the outbreak, but for Huang, the government should focus on domestic recovery after…

China’s will face an increasingly hostile world over the next five years, meaning its policy plan should be focused on its vast domestic market, home-grown technological innovation and improving its citizens’ welfare, according to recommendations in a new paper.The report by the Chinese Academy of Social Sciences (CASS), a think tank affiliated with the State Council, foresees the next five years presenting “major changes unseen in a century” for China, as “the strategic game between…

The commitment of students in bringing people together will be the focus of the 39th annual Student of the Year Awards organised by the South China Morning Post.With the theme “Leading for a better society”, two new awards this year include a special prize for the most nurturing environment, which will go to a school and its students, and another for mentorship.A total of 11 awards in nine categories, including science, maths, languages, sports, and visual and performing arts, will be presented…

One day after saying that the White House COVID-19 task force would be winding down, President Donald Trump said Wednesday it would continue indefinitely but focus more on rebooting the economy.

Pfizer Inc said on Friday it is in talks to shift more of its medicine production to outside contractors as it prepares for large-scale production of an experimental vaccine to prevent COVID-19, should it prove safe and effective.

Pfizer Inc said on Friday it is in talks to shift more of its medicine production to outside contractors as it prepares for large-scale production of an experimental vaccine to prevent COVID-19, should it prove safe and effective.

U.S. President Donald Trump said on Wednesday his White House coronavirus task force would remain in place but with a focus on medical treatments and easing restrictions on businesses and social life and perhaps with different advisers. This report produced by Chris Dignam.

Title: Phone-Focused Parents a Danger to Their Kids at Playground
Category: Health News
Created: 4/25/2015 12:00:00 AM
Last Editorial Review: 4/27/2015 12:00:00 AM

Title: Focus on Healthy Foods, Not Avoiding 'Bad' Ones, for Heart Health: Study
Category: Health News
Created: 4/25/2016 12:00:00 AM
Last Editorial Review: 4/25/2016 12:00:00 AM

PMC marked its 10th anniversary in 2010 with a celebratory event at its annual Advisory Committee meeting, held at the National Library of Medicine last June. This milestone event was recently featured in the February 17th edition of NLM In Focus, in an article NLM Milestones: The Hits Just Keep on Coming. For more information on the ten years of PMC, see the article in the May-June issue of the NLM Technical Bulletin.

Neutralizing antibodies specific for respiratory syncytial virus (RSV) represent a major protective mechanism against RSV infection, as demonstrated by the efficacy of the immune-prophylactic monoclonal antibody palivizumab in preventing RSV-associated lower respiratory tract infections in premature infants. Accordingly, the RSV neutralization assay has become a key functional method to assess the neutralizing activity of serum antibodies in preclinical animal models, epidemiology studies, and clinical trials. In this study, we qualified a 24-h, fluorescent focus-based microneutralization (RSVA FFA-MN) method that requires no medium exchange or pre- or postinfection processing to detect green fluorescent protein-expressing RSV strain A2 (RSVA-GFP)-infected cells, using a high-content imaging system for automated image acquisition and focus enumeration. The RSVA FFA-MN method was shown to be sensitive, with a limit of detection (LOD) and limit of quantitation (LOQ) of 1:10, or 3.32 log₂; linear over a range of 4.27 to 9.65 log₂ 50% inhibitory concentration (IC₅₀); and precise, with intra- and interassay coefficients of variation of <21%. This precision allowed the choice of a statistically justified 3-fold-rise seroresponse cutoff criterion. The repeatability and robustness of this method were demonstrated by including a pooled human serum sample in every assay as a positive control (PC). Over 3 years of testing between two laboratories, this PC generated data falling within 2.5 standard deviations of the mean 98.7% of the time (n = 1,720). This high-throughput and reliable RSV microneutralization assay has proven useful for testing sera from preclinical vaccine candidate evaluation studies, epidemiology studies, and both pediatric and adult vaccine clinical trials.

ABSTRACTBackground:The focused assessment with sonography for HIV-associated tuberculosis (TB) (FASH) ultrasound protocol has been increasingly used to help clinicians diagnose TB. We sought to quantify the diagnostic utility of FASH for TB among individuals with HIV in Malawi.Methods:Between March 2016 and August 2017, 210 adults with HIV who had 2 or more signs and symptoms that were concerning for TB (fever, cough, night sweats, weight loss) were enrolled from a public HIV clinic in Lilongwe, Malawi. The treating clinicians conducted a history, physical exam, FASH protocol, and additional TB evaluation (laboratory diagnostics and chest radiography) on all participants. The clinician made a final treatment decision based on all available information. At the 6-month follow-up visit, we categorized participants based on clinical outcomes and diagnostic tests as having probable/confirmed TB or unlikely TB; association of FASH with probable/confirmed TB was calculated using Fisher's exact tests. The impact of FASH on empiric TB treatment was determined by asking the clinicians prospectively about whether they would start treatment at 2 time points in the baseline visit: (1) after the initial history and physical exam; and (2) after history, physical exam, and FASH protocol.Results:A total of 181 participants underwent final analysis, of whom 56 were categorized as probable/confirmed TB and 125 were categorized as unlikely TB. The FASH protocol was positive in 71% (40/56) of participants with probable/confirmed TB compared to 24% (30/125) of participants with unlikely TB (odds ratio=7.9, 95% confidence interval=3.9,16.1; P<.001). Among those classified as confirmed/probable TB, FASH increased the likelihood of empiric TB treatment before obtaining any other diagnostic studies from 9% (5/56) to 46% (26/56) at the point-of-care. For those classified as unlikely TB, FASH increased the likelihood of empiric treatment from 2% to 4%.Conclusion:In the setting of HIV coinfection in Malawi, FASH can be a helpful tool that augments the clinician's ability to make a timely diagnosis of TB.

Microsoft earlier announced it will share new information on the Xbox Series X every month in 2020 calling it "Xbox 20/20." The first event will be held on May 7th at 8am PT / 11am ET and will focus on gameplay from third-party partners. 

The event in June has now been revealed it will focus on platform and services, according to Bloomberg.

It is possible the June event will see the unveiling of the long rumored weaker next generation Xbox, codenamed Lockhart, with an expected official name of Xbox Series S. The price and launch date for the Xbox Series X is also possible, as well as information on Game Pass, Xbox Live Gold and Project xCloud. 

The July event will be focused on upcoming first-party games from Xbox Game Studios. 

"These monthly moments will take place throughout the rest of the year and will be a way for us to engage, connect and celebrate with you about what’s in store for the next generation of gaming, including what’s next for Xbox Series X, Xbox Game Studios, Xbox Game Pass and Project xCloud," said Microsoft. "Every month will bring something different. Stay tuned to Xbox Wire for more details."

The Xbox Series X will launch in Holiday 2020.

A life-long and avid gamer, William D'Angelo was first introduced to VGChartz in 2007. After years of supporting the site, he was brought on in 2010 as a junior analyst, working his way up to lead analyst in 2012. He has expanded his involvement in the gaming community by producing content on his own YouTube channel and Twitch channel dedicated to gaming Let's Plays and tutorials. You can contact the author at wdangelo@vgchartz.com or on Twitter @TrunksWD.

Full Article - https://www.vgchartz.com/article/443395/xbox-series-x-june-event-to-focus-on-platform-and-services/

Focused ultrasound, the researchers hope, could revolutionize treatment for conditions from Alzheimer's to epilepsy to brain tumors -- and even help repair the devastating damage caused by stroke.

Gaming platforms have earned serious clout with investors in recent years. Add in the VC excitement surrounding collaboration tools and it’s no surprised there’s interest in backing another gaming chat app. Guilded is creating a chat platform designed for competitive gaming and esports that focuses heavily on keeping gamers organized and connected with their teams. […]

Pfizer Inc said on Friday it is in talks to shift more of its medicine production to outside contractors as it prepares for large-scale production of an experimental vaccine to prevent COVID-19, should it prove safe and effective.

It is "far too early" to even think about relaxing lockdown measures, Dominic Raab has said, after another 717 coronavirus patients died over night.

Recent deaths have stood out, but scientists say they must be interpreted with caution

Amid the steady stream of stories on the lives lost to coronavirus are cases that stand out as remarkable. In the past month, at least two pairs of twins have died in Britain and two pairs of brothers, all within hours or days of each other. But do the deaths point to genetic factors that make some more likely than others to succumb to the disease?

Most scientists believe that genes play a role in how people respond to infections. A person’s genetic makeup may influence the receptors that the coronavirus uses to invade human cells. How resilient the person is to the infection, their general health, and how the immune system reacts will also have some genetic component.

It will be important to one day learn the true origin story of the global pandemic to defend against similar outbreaks in the future, Health Minister Patty Hajdu acknowledged Monday.

The Canadian Institutes of Health Research (CIHR) put off its regular $275-million competition this spring to focus on delivering federal grants related to the novel coronavirus.

Securing more personal protective equipment was top of the agenda for the Prime Minister as he returned to work, his official spokesman said.

A Winnipeg woman who was a subject of misogynistic comments in a private group chat involving NHL players said she will continue her campaign of encouraging body acceptance.

Former Liverpool striker Emile Heskey believes Roberto Firmino doesn't focus on scoring goals, instead providing the 'gel' that glues his side together.

Old Trafford officials believe no club will get close to £100m transfers in the upcoming window

Tomori has been studying towards a degree in business management

Ole Gunnar Solskjaer has confirmed he still wants to improve his attack - despite Ed Woodward issuing a warning about Manchester United's spending this summer.

Chris Waller continues his big race domination, taking out The Everest at Randwick with Yes Yes Yes, on a day marked by protests and calls for change after an investigation revealed widespread slaughter and abuse of former racehorses in Australian abattoirs.

Redfin launched this service in late 2017, just after creating RedfinNow, but has struggled to create the software and on-demand operations until now.

While tough coronavirus restrictions have saved thousands of lives, Scott Morrison says the country is now in a position to start clawing back some of the $4 billion lost every week that restrictions continue. Here are the key takeaways from his press conference.

How do you avoid overload when you have time to do everything?

The new White House communications team is scrambling to keep Trump on TV but limit his ability to offer dangerous medical advice. The goal is to show him as a leader and push his reelection message. The problem is that Trump almost certainly will sabotage the plan.

The Association of Clinical Research Organizations (ACRO) convenes discussion series that seeks to advance an industry with important health and economic impacts...

COVID-19 continues to dominate the news cycle as we all try to maintain business as usual under the shadow of the pandemic. Just about every area of society and business has been hit and Life Sciences is no exception; the impact of the virus has been felt in every corner of the industry and our monthly issues aim to cut through the confusion to shed a light on that impact.

Two Chicago men have been arrested on federal charges for their alleged roles in conspiracies to provide material support and/or to commit terrorist acts against overseas targets.

The findings reported in the Bureau of Justice Statistics’ (BJS) report, Sexual Victimization in Juvenile Facilities Reported by Youth, 2008-2009, bring into focus the dire circumstances that too many youth in juvenile correctional facilities have to endure.

“Secretary Vilasck and I are committed to improving our understanding of how particular agricultural markets function,” said Attorney General Holder.

The workshop explores the appropriate role for antitrust and regulatory enforcement in the dairy industry.

The Department of Justice and the U.S. Department of Agriculture today held the fourth of five joint public workshops to explore the appropriate role for antitrust and regulatory enforcement in American agriculture.

"The Criminal Division, along with our partners in the U.S. Attorneys Offices, is firmly committed to supporting you in our collective mission to prevent and deter any attempts to defraud the American people of the money invested in our future through the Recovery Act," said Assistant Attorney General Breuer.

The Department of Justice and the U.S. Department of Agriculture (USDA) today held the fifth of five joint public workshops to explore the appropriate role for antitrust and regulatory enforcement in American agriculture.

Attorney General Eric Holder today announced the formation of a Financial Fraud Enforcement Task Force Working Group to focus specifically on fraud in the energy markets.

Senior environmental enforcement officials from the U.S. Justice Department and Environmental Protection Agency (EPA) toured sites in Newark, N.J., today and met with federal partners and with environmental and community organizations to discuss mutual efforts to address environmental challenges and enforce environmental laws, and in particular efforts to achieve environmental justice.