activities

Speaking Activities That Don't Suck

I have English Teacher X's obra prima to read next and have enjoyed the other ebooks - they include a lot of sensible and realistic advice - but I didn't enjoy Speaking Activities that Don't Suck as much.




activities

The Challenging Job of an Electrical Commissioning Engineer (Activities and Real World Examples)

This article aims to cover the activity of electrical commissioning. Such a task in its entirety would be immense. Commissioning can mean many things in different instances. This article aims to give a philosophical and high level conceptual overview of... Read more

The post The Challenging Job of an Electrical Commissioning Engineer (Activities and Real World Examples) appeared first on EEP - Electrical Engineering Portal.




activities

Resolution 55 - (Rev. Geneva, 2022) - Mainstreaming a gender perspective in ITU Telecommunication Standardization Sector activities

Resolution 55 - (Rev. Geneva, 2022) - Mainstreaming a gender perspective in ITU Telecommunication Standardization Sector activities




activities

Resolution 92 - (Rev. Geneva, 2022) - Enhancing the standardization activities in the ITU Telecommunication Standardization Sector related to non-radio aspects of international mobile telecommunications

Resolution 92 - (Rev. Geneva, 2022) - Enhancing the standardization activities in the ITU Telecommunication Standardization Sector related to non-radio aspects of international mobile telecommunications




activities

Short Answer- Build better k12 writers through social, engaging writing activities

I love technology built by teachers—it’s just different. You can feel the truth and passion behind it. It has features that you know were intentionally considered by someone who has been in the classroom. Short Answer is a fantastic writing tool that was obviously built by teachers solving real problems for real students. The best!...




activities

Why Wildfires Started by Human Activities Can Be More Destructive and Harder To Contain

Heavy equipment working near dry brush sparked a destructive wildfire near Riverside, Calif., in September 2024.




activities

Looking for new activities? Google wants you to turn to its navigation app

Google is adding more generative AI features to popular navigation apps such as Google Maps and Waze.




activities

Nonspecific DNA binding by P1 ParA determines the distribution of plasmid partition and repressor activities [Microbiology]

The faithful segregation, or “partition,” of many low-copy number bacterial plasmids is driven by plasmid-encoded ATPases that are represented by the P1 plasmid ParA protein. ParA binds to the bacterial nucleoid via an ATP-dependent nonspecific DNA (nsDNA)-binding activity, which is essential for partition. ParA also has a site-specific DNA-binding activity to the par operator (parOP), which requires either ATP or ADP, and which is essential for it to act as a transcriptional repressor but is dispensable for partition. Here we examine how DNA binding by ParA contributes to the relative distribution of its plasmid partition and repressor activities, using a ParA with an alanine substitution at Arg351, a residue previously predicted to participate in site-specific DNA binding. In vivo, the parAR351A allele is compromised for partition, but its repressor activity is dramatically improved so that it behaves as a “super-repressor.” In vitro, ParAR351A binds and hydrolyzes ATP, and undergoes a specific conformational change required for nsDNA binding, but its nsDNA-binding activity is significantly damaged. This defect in turn significantly reduces the assembly and stability of partition complexes formed by the interaction of ParA with ParB, the centromere-binding protein, and DNA. In contrast, the R351A change shows only a mild defect in site-specific DNA binding. We conclude that the partition defect is due to altered nsDNA binding kinetics and affinity for the bacterial chromosome. Furthermore, the super-repressor phenotype is explained by an increased pool of non-nucleoid bound ParA that is competent to bind parOP and repress transcription.




activities

Kinetic investigation of the polymerase and exonuclease activities of human DNA polymerase ϵ holoenzyme [DNA and Chromosomes]

In eukaryotic DNA replication, DNA polymerase ε (Polε) is responsible for leading strand synthesis, whereas DNA polymerases α and δ synthesize the lagging strand. The human Polε (hPolε) holoenzyme is comprised of the catalytic p261 subunit and the noncatalytic p59, p17, and p12 small subunits. So far, the contribution of the noncatalytic subunits to hPolε function is not well understood. Using pre-steady-state kinetic methods, we established a minimal kinetic mechanism for DNA polymerization and editing catalyzed by the hPolε holoenzyme. Compared with the 140-kDa N-terminal catalytic fragment of p261 (p261N), which we kinetically characterized in our earlier studies, the presence of the p261 C-terminal domain (p261C) and the three small subunits increased the DNA binding affinity and the base substitution fidelity. Although the small subunits enhanced correct nucleotide incorporation efficiency, there was a wide range of rate constants when incorporating a correct nucleotide over a single-base mismatch. Surprisingly, the 3'→5' exonuclease activity of the hPolε holoenzyme was significantly slower than that of p261N when editing both matched and mismatched DNA substrates. This suggests that the presence of p261C and the three small subunits regulates the 3'→5' exonuclease activity of the hPolε holoenzyme. Together, the 3'→5' exonuclease activity and the variable mismatch extension activity modulate the overall fidelity of the hPolε holoenzyme by up to 3 orders of magnitude. Thus, the presence of p261C and the three noncatalytic subunits optimizes the dual enzymatic activities of the catalytic p261 subunit and makes the hPolε holoenzyme an efficient and faithful replicative DNA polymerase.




activities

Shifting Science Instruction to the Coronavirus: New Activities, Units

A small group of science teachers in Missouri is using the coronavirus as a teachable moment that's aligned to the Next Generation Science Standards.




activities

DSB Highlights Activities for National Small Business Week/Month 2024

There are nearly 28-thousand small businesses in the State of Delaware. Each year, the month of May is set aside as a special time to celebrate small businesses, their courage, community efforts, and hard work. The Delaware Division of Small Business (DSB) is highlighting activities that do this taking place during National Small Business Month, and National Small Business Week (NSBW April 28 – May 4, 2024).




activities

DPH Shares Activities As Part Of Falls Prevention Awareness Week

DOVER, DE (Sept. 14, 2022) – Falls can result in broken bones, head injuries, and temporary or permanent disabilities, and the Delaware Coalition for Injury Prevention’s Falls Prevention Team says it takes community effort to prevent them.  The Injury Prevention Coalition operates under the Division of Public Health’s (DPH) Office of Emergency Medical Services section. In recognition […]




activities

dia student activities manual

dia student activities manual




activities

Health Tip: Find Activities You Enjoy

Title: Health Tip: Find Activities You Enjoy
Category: Health News
Created: 8/31/2018 12:00:00 AM
Last Editorial Review: 8/31/2018 12:00:00 AM




activities

Everyday Activities That Can Cut Your Odds for Dementia

Title: Everyday Activities That Can Cut Your Odds for Dementia
Category: Health News
Created: 8/12/2022 12:00:00 AM
Last Editorial Review: 8/15/2022 12:00:00 AM




activities

Why you should be using a VPN to safeguard your stock trading activities

Every stock trader should consider a virtual private network to safeguard their trading, according to tech guru Kurt "CyberGuy" Knutsson.



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activities

Pakistan limits outdoor activities, market hours to curb air pollution-related illness

LAHORE — Pakistan's Punjab province banned most outdoor activities and ordered shops, markets and malls in some areas to close early from Monday (Nov 11) to curb illnesses caused by intense air pollution. The province has closed educational institutions and public spaces like parks and zoos until Nov. 17 in places including Lahore, the world's most polluted city in terms of air quality, according to Swiss group IQAir's live ratings. The districts of Lahore, Multan, Faisalabad and Gujranwala have seen an unprecedented rise in patients with respiratory diseases, eye and throat irritation, and pink eye disease, the Punjab government said in an order issued late on Sunday. The new restrictions will also remain in force until Nov. 17. "The spread of conjunctivitis/ pink eye disease due to bacterial or viral infection, smoke, dust or chemical exposure is posing a serious and imminent threat to public health," the Punjab government said.




activities

Shiv Sena (UBT) expels ex-Hingoli MP Wankhede for 'anti-party' activities

In an abrupt move, the Shiv Sena (UBT) has expelled its former Hingoli Lok Sabha MP Subhash Wankhede from the party for alleged 'anti-party' activities




activities

Groupon cuts over 500 staff, plans to focus ‘only on mission-critical activities’ from now on

Chicago-based Groupon today laid off more than 500 of its employees — 15% of its 3,416-person headcount — according to posts from former employees on social media. The reduction impacted workers in teams including merchant development, sales, recruiting, engineering, product and marketing. Groupon confirmed the layoffs to TechCrunch after the publication of the story. “Our […]

© 2024 TechCrunch. All rights reserved. For personal use only.




activities

Govt Warns Of "Unauthorized", "Ill-intentioned" Activities Of MSME Export Promotion Council

On Saturday, the Ministry of Micro, Small & Medium Enterprises (MSMEs) in a press note warned of "unauthorized and ill-intentioned" activities of the MSME Export Promotion Council and also clarified that the government is not associated with the council. "Ministry




activities

Canada Orders TikTok to Terminate all Business Activities Citing National Security Concerns

Canada has instructed TikTok to cease its operations within the nation, citing unspecified "national security risks" linked to the company and its parent, ByteDance. This decision mandates TikTok to terminate all business activities in Canada. However, the Canadian government has not




activities

Royal Enfield Gears Up For The 2024 Motoverse Event In Goa: New Models & Thrilling Activities Assured

Royal Enfield is gearing up to host the 2024 Motoverse event in Goa from the 22nd to the 24th of this month. This event will feature a showcase of new models, updates, and accessories from Royal Enfield. Enthusiasts can expect an




activities

India Bike Week 2024: Exciting Activities & Ticket Details

The India Bike Week is a highly anticipated event for motorcycle enthusiasts across the country. Traditionally held in Goa, this annual gathering takes place in early December. This year, it is scheduled for December 6th and 7th at Vagator, Goa. Ticket




activities

Phenoxy-1,2-dioxetane-Based Activatable Chemiluminescent Probes: Tuning of Photophysical Properties for Tracing Enzymatic Activities in Living Cells

Analyst, 2024, Accepted Manuscript
DOI: 10.1039/D4AN01082E, Critical Review
Open Access
Jagpreet Singh Sidhu, Gurjot Kaur, Atharva Rajesh Chavan, Mandeep Chahal, Rajeev Taliyan
The use of chemiluminophores for tracing enzymatic activities in live-cell imaging has gained significant attention, making them valuable tools for diagnostic applications. Among various chemiluminophores, the phenoxy-1,2-dioxetane scaffold exhibits significant...
The content of this RSS Feed (c) The Royal Society of Chemistry




activities

Extreme weather for kids : lessons and activities all about hurricanes, tornadoes, blizzards, and more! / Matthew Cappucci ; illustrated by Stephanie Hathaway

Cappucci, Matthew, author




activities

Tailoring of novel morpholine-sulphonamide linked thiazole moiety as dual targeting DHFR/DNA gyrase inhibitors: Synthesis, antimicrobial, antibiofilm activities and DFT with molecular modelling studies

New J. Chem., 2024, Accepted Manuscript
DOI: 10.1039/D3NJ05774G, Paper
Moaz M. Abdou, Essam Eliwa, Mohamed Abdel Reheim, Ahmed Abu-Rayyan, Shimaa M. Abd El-Gilil, Mohammed Abu-Elghait , Mohamed H. Sharaf, Mohamed Kalaba, Ahmed Halawa, Walid Elgammal
Herein, the chemical synthesis of new thiazoles-based benzenesulfonamide-linked morpholine 4a,b–7 via late-stage thiazolation of the corresponding thiosemicarbazone 3 was reported. The skeletal formulas of the new compounds were confirmed by...
The content of this RSS Feed (c) The Royal Society of Chemistry




activities

Deepavali weekend witnesses surge in tourist activities in Karnataka

The demand has been so much that local tour operators are struggling to arrange for resources for those who are booking trips




activities

Presenting Bengaluru’s weekend activities




activities

Effect of ZnMgO2 nanoparticles used as a nanofertilizer: promoting the growth activities of rice seedlings

Environ. Sci.: Nano, 2024, 11,1571-1581
DOI: 10.1039/D3EN00770G, Paper
Sajid Mehmood, Niteesh Kumar, Aadil Mansoori, Madan Mohan, Anirudh Kumar, Tanmay Kumar Ghorai
Novel ZnMgO2 bimetallic nanoparticles were synthesized using Cinchona succirubra leaf extract and used as a nano fertilizer, promoting the growth activities of rice seedlings, α-amylase and antioxidant activity with average particle sizes of 24.8 nm.
The content of this RSS Feed (c) The Royal Society of Chemistry




activities

Gujarat introduces stricter safety rules for boating activities




activities

Minister promises IBM all support to expand activities in Kerala




activities

Finance Ministry notifies new FDI limits for satellite-related activities under FEMA

Finance Ministry’s new FDI limits for satellite activities, effective April 16, allow 100% FDI in the space sector with specific limits for different activities




activities

Review meeting held to check Maoist activities along Telangana’s border with Chhattisgarh




activities

Pakistan media accuses 8 Indian mission staffers of ‘anti-Pakistan activities’

The media leak claimed that the officials were working for either RAW or for Intelligence Bureau.




activities

The Structure of Firms' International Activities [electronic journal].




activities

Medicinal plant resin natural products: structural diversity and biological activities

Nat. Prod. Rep., 2024, 41,1471-1542
DOI: 10.1039/D4NP00007B, Review Article
Madhu Babu Sura, Yong-Xian Cheng
This review explores medicinal plant resin natural products from six genera, encompassing 1115 structures and their biological activities, offering insights into the chemical and biological profiling of plant resins produced under various stress.
The content of this RSS Feed (c) The Royal Society of Chemistry




activities

Siccanin-related drimane meroterpenoids: biological activities and synthesis

Nat. Prod. Rep., 2024, Advance Article
DOI: 10.1039/D4NP00025K, Review Article
Shengxin Sun, Xia Wang, Nvdan Hu, Shiqi Fu, Shengkun Li
This review describes the isolation, structural characteristics, bioactivities and divergent synthetic strategies of siccanin-related drimane meroterpenoids.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




activities

Reactivities of tertiary phosphines towards allenic, acetylenic, and vinylic Michael acceptors

Chem. Sci., 2024, 15,18111-18126
DOI: 10.1039/D4SC04852K, Edge Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Feng An, Jan Brossette, Harish Jangra, Yin Wei, Min Shi, Hendrik Zipse, Armin R. Ofial
Combined experimental and quantum-chemical studies were used to characterise the philicity/fugality features of tertiary phosphines and Michael acceptors in phospha-Michael reactions, which are key steps in phosphine-catalysed organic reactions.
The content of this RSS Feed (c) The Royal Society of Chemistry




activities

HC tells authorities to prevent anti-social activities by other methods before resorting to KAAPA




activities

The synthesis and bioactivities of ROCK2 inhibitors with 1,2-dithiolan-3-yl motif

RSC Med. Chem., 2024, 15,3576-3596
DOI: 10.1039/D4MD00438H, Research Article
Ruolin Cao, Fangyu Du, Zhiqiang Liu, Pengcheng Cai, Minggang Qi, Wei Xiao, Xuefei Bao, Guoliang Chen
Rho-associated coiled-coil containing kinase (ROCK) plays an important role in inflammation.
The content of this RSS Feed (c) The Royal Society of Chemistry




activities

Above-normal pre-monsoon rain triggers agriculture activities in Raichur district of Karnataka

The district received 26.5 mm of rain in 72 hours against the average of 1.9 mm




activities

Newly synthesized sulfonamide derivatives explored for DNA binding, enzyme inhibitory, and cytotoxicity activities: a mixed computational and experimental analyses

RSC Adv., 2024, 14,35047-35063
DOI: 10.1039/D4RA06412G, Paper
Open Access
Nasima Arshad, Yasir Mehmood, Hammad Ismail, Fouzia Perveen, Aneela Javed, Pervaiz Ali Channar, Aamer Saeed, Sadia Naseem, Fatima Naseer
This work reports synthesis, characterization, DNA, enzyme binding and cytotoxicity activity of three 4-((3-arylthiazolo[3,4-d]isoxazol-5-yl)amino)benzene sulfonamide derivatives with a thaizaole(3,4-d)isoxazole-based fused ring heterocyclic system.
The content of this RSS Feed (c) The Royal Society of Chemistry




activities

A facile synthesis of iron oxide nanoparticles as a nano-sensor to detect levofloxacin and ciprofloxacin in human blood and evaluation of their biological activities

RSC Adv., 2024, 14,36093-36100
DOI: 10.1039/D4RA05024J, Paper
Open Access
Erum Hasan, Ziana Manzar, Nabeel Haroon, Ali Raza, Syed Nawazish Ali, Mehreen Lateef, Sabira Begum
New bioactive magnetic nanoparticles were synthesized and stabilized by 3-aminobenzoic acid (3-ABA) utilized in detection of levofloxacin and ciprofloxacin.
The content of this RSS Feed (c) The Royal Society of Chemistry




activities

Effects of human activities and climate change on water quality and health risks of typical urban river in arid/semi-arid areas, a ten-year historical analysis

Environ. Sci.: Water Res. Technol., 2024, Accepted Manuscript
DOI: 10.1039/D4EW00689E, Paper
Xiang Zhu, Hanjie Zheng, Dezhi Zuo, Qingqing Pang, Lei Xie, Longmian Wang, Jin-Ying Xi, Lin-Feng Tian, Jing Wu, Wenjuan Jiang, Jiawei Sun, Hongyu Zhao, Jianhua Jin
Water resources are scarce in arid and semi-arid regions. Urban rivers, vital water sources, are susceptible to the influences of climate change and human activities. However, there have been few...
The content of this RSS Feed (c) The Royal Society of Chemistry




activities

Oxygen redox activities governing high-voltage charging reversibility of Ni-rich layered cathodes

Energy Environ. Sci., 2024, Advance Article
DOI: 10.1039/D4EE03832K, Paper
Gi-Hyeok Lee, Suwon Lee, Jiliang Zhang, Bernardine L. D. Rinkel, Matthew J. Crafton, Zengqing Zhuo, Youngju Choi, Jialu Li, Junghoon Yang, Jongwook W. Heo, Byungchun Park, Bryan D. McCloskey, Maxim Avdeev, Wanli Yang, Yong-Mook Kang
A schematic illustration indicative of the improved structural reversibility through stabilizing oxidized oxygen by Al doping.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




activities

Inter-{alpha}-inhibitor heavy chain-1 has an integrin-like 3D structure mediating immune regulatory activities and matrix stabilization during ovulation [Glycobiology and Extracellular Matrices]

Inter-α-inhibitor is a proteoglycan essential for mammalian reproduction and also plays a less well-characterized role in inflammation. It comprises two homologous “heavy chains” (HC1 and HC2) covalently attached to chondroitin sulfate on the bikunin core protein. Before ovulation, HCs are transferred onto the polysaccharide hyaluronan (HA) to form covalent HC·HA complexes, thereby stabilizing an extracellular matrix around the oocyte required for fertilization. Additionally, such complexes form during inflammatory processes and mediate leukocyte adhesion in the synovial fluids of arthritis patients and protect against sepsis. Here using X-ray crystallography, we show that human HC1 has a structure similar to integrin β-chains, with a von Willebrand factor A domain containing a functional metal ion-dependent adhesion site (MIDAS) and an associated hybrid domain. A comparison of the WT protein and a variant with an impaired MIDAS (but otherwise structurally identical) by small-angle X-ray scattering and analytical ultracentrifugation revealed that HC1 self-associates in a cation-dependent manner, providing a mechanism for HC·HA cross-linking and matrix stabilization. Surprisingly, unlike integrins, HC1 interacted with RGD-containing ligands, such as fibronectin, vitronectin, and the latency-associated peptides of transforming growth factor β, in a MIDAS/cation-independent manner. However, HC1 utilizes its MIDAS motif to bind to and inhibit the cleavage of complement C3, and small-angle X-ray scattering–based modeling indicates that this occurs through the inhibition of the alternative pathway C3 convertase. These findings provide detailed structural and functional insights into HC1 as a regulator of innate immunity and further elucidate the role of HC·HA complexes in inflammation and ovulation.




activities

Service activities shrink to all-time low; PMI hits near zero

India's service sector recorded largest contraction in business activity and new orders in April.




activities

NDMA issues guidelines for restarting industrial activities to avoid Vizag-type tragedy

In a communication to all states and union territories, the NDMA said due to several weeks of lockdown and the closure of industrial units, it is possible that some of the operators might not have followed the established standard operating procedures.




activities

No tourism activities despite reopening of Kaghan valley road

MANSEHRA: Though Kaghan-Naran section of Mansehra-Naran-Jalkhad road has been reopened to traffic following the suspension of five consecutive months, the tourism activities in the valley are yet to be resumed.The road, which was blocked due to heavy snowfall in Kaghan valley in December 2019, was...




activities

“I did not announce ban lift on religious activities in Enugu” – Archbishop Ede

The Chairman of the Christian Council of Nigeria, Enugu State chapter, Archbishop Barr. Christopher Ede, has stated that he did not announce that ban on religious activities have been lifted in Enugu State, as is being erroneously peddled in the media. Reacting to a media report credited to him to the effect that Enugu State […]

“I did not announce ban lift on religious activities in Enugu” – Archbishop Ede