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The Next Event on God’s Prophetic Timetable, Part 2 (1 Thessalonians 4:13-18)

Check here each week to keep up with the latest from John MacArthur's pulpit at Grace Community Church.




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Acceptable Worship, Part 1 (John 4:20-24)

Check here each week to keep up with the latest from John MacArthur's pulpit at Grace Community Church.




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Acceptable Worship, Part 2 (John 4:20-24)

Check here each week to keep up with the latest from John MacArthur's pulpit at Grace Community Church.




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Letter: Holding ex-managers accountable for irregular spending





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Keeping the Divine Timetable




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'Emilia Perez': From Mexican cartel leader to Tel Aviv's operating table


Emilia Perez tells a colorful story of cartels, gender, and redemption.





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Debt cannot become acceptable new normal in climate financing: PM Shehbaz

Prime Minister Shehbaz Sharif on Tuesday said that debt cannot become the “acceptable new normal” in climate financing, as he addressed the challenges faced by developing countries within the global climate finance framework.

His statement came during a Climate Finance Round Table Conference organised by Pakistan on the sidelines of the two-day World Leaders Climate Action Summit, also known as COP29, currently being held in Azerbaijan’s capital of Baku.

“We stand at a crucial threshold where global climate finance framework must be redefined to effectively meet the needs of vulnerable nations,” PM Shehbaz said.

He explained that financing in the form of loans increases the debt of developing nations and pushes them towards “mounting debt traps” which he referred to as “death traps”.

He added, “Debt cannot become the acceptable new normal in climate financing which is why we must resume focus on non-debt financing solutions enabling countries to fund climate initiatives.”

“Despite years of promises and commitments, the gaps are growing, leading to aggregate barriers in achieving objectives of the UN Framework Convention on Climate Change (UNFCCC).”

PM Shehbaz called climate financing an “urgent need of the hour”, stating that developing countries need to deliver Nationally Determined Contributions (NDCs) and “need an estimated $6.8 trillion by 2030 to implement less than half of their current NDCs.”

The prime minister further urged donor countries to “fulfil their commitment” which is 4.7 per cent of their gross national product (GNP) and capitalise on existing climate funds.

“One such commitment is a $100bn annual climate pledge established a decade ago at COP15 [which] is now reported by OECD to have reached only $160bn,” he said.

Prime Minister Shehbaz Sharif, flanked by Turkish President Tayyip Erdogan and Britain’s Prime Minister Keir Starmer, attends the Opening Ceremony of the United Nations climate change conference COP29 in Baku, Azerbaijan on Nov 12, 2024. — Reuters

PM Shehbaz said that Pakistan can relate to the “agony and pain of other vulnerable countries”, highlighting how the country faced two devastating floods.

“In 2022, one-third of Pakistan was under water and the country had to repurpose all development and climate funds for financing basic relief and humanitarian efforts,” he said.

Pakistan is ranked among the top 10 most climate-vulnerable countries, according to the Global Climate Risk Index 2021. It has faced increasingly frequent and severe weather events, such as unprecedented floods, intense monsoon rains, devastating heat waves, rapid glacial melting and glacial lake outburst floods.

Pakistan witnessed devastating floods during the 2022 monsoon season, induced by climate change, resulting in the loss of at least 1,700 lives.

With 33 million people affected and swathes of agricultural land washed away, the damage incurred losses worth $30 billion, according to government estimates.

In June 2024, a heat wave brought record-high temperatures, severely impacting public health and agriculture.

Participating world leaders and delegates pose for a family photo during the United Nations Climate Change Conference (COP29) in Baku on Nov 12, 2024. — AFP

While emphasising transparency and coordination in financial commitments made to developing countries, he stated that Pakistan alongside other developing countries, calls for stronger more equitable climate finance mechanisms under the UNFCCC.

He reiterated the pertinent need for reform of international financial architecture saying that “now is the time to build up on the momentum for international financial reforms” so that no nation is left behind in the global response to climate change.

PM to highlight ‘balanced and ambitious’ climate action

According to the Foreign Office, several high-level events and roundtable discussions hosted by Pakistan will also take place at the Pakistan Pavilion during COP29.

It added that at COP29, Pakistan will call for “balanced and ambitious progress on all issues such as loss and damage, adaptation, mitigation and means of implementation”.

“It will seek predictable financing to address developing countries’ climate goals. Pakistan will also underscore the historical responsibility and the principle of Equity and Common but Differentiated Responsibility and call on developed nations to undertake deeper emission cuts.”

PM Shehbaz was warmly received by Azerbaijan President Ilham Aliyev and UN Secretary-General António Guterres upon his arrival at the summit venue today, state-run Radio Pakistan reported.

PM Shehbaz Sharif is received by Azerbaijan President Ilham Aliyev and UN Secretary-General António Guterres as he arrives at the venue to attend COP29 in Baku on November 12. — Radio Pakistan

The first day of the Climate Action Summit will feature statements from various heads of states, beginning from 3pm Pakistan time.

Speakers include the United Kingdom’s PM Keir Starmer, Saudi Arabia’s Crown Prince Mohammed bin Salman, Turkiye President Recep Tayyip Erdoğan and Ukraine President Volodymyr Zelenskyy.

Among those scheduled to address the high-level meeting tomorrow, besides PM Shehbaz, are Bangladesh leader Muhammad Yunus and Russia’s PM Mikhail Mishustin.

PM Shehbaz is listed as the 37th speaker out of 47 leaders during the session scheduled from 10am to 6pm (Pakistan time).

The prime minister will also participate in a high-level event ‘Glaciers 2025: Actions for Glaciers’ organised by Tajikistan President Emomali Rahmon on the protection of glaciers.

PM Shehbaz will also hold separate meetings with the prime ministers of Denmark and the Czech Republic, who are also attending COP-29, Radio Pakistan stated.

PM meets world leaders

On the sidelines of COP29, PM Shehbaz interacted with UAE President Sheikh Mohammed bin Zayed Al Nahyan and discussed cooperation on climate change and matters of mutual interest, Radio Pakistan reported.

The premier also met with PM Starmer, where the two discussed enhancing Pakistan-UK cooperation.

He also met with Turkish President Recep Tayyip Erdogan and his wife Emine Erdogan, where they discussed environmental pollution as well as matters of mutual interest between the two friendly nations, the report added.

In his interactions with Nepal’s President Ramchandra Paudel and Bangladesh’s Yunus, PM Shehbaz discussed growing temperatures, the threat of rising sea levels, and forest conservation in South Asia.

Kazakhstan President Kassym-Jomart Tokayev and PM Shehbaz explored strengthening bilateral relations as well as expanding regional connectivity.

In his meetings with Uzbekistan President Shavkat Mirziyoyev and Tajikistan’s Rahmon, the leaders spoke about the conservation of glaciers and water resources in Central Asian countries and Pakistan.

They also exchanged views on expanding communication links among Pakistan, Tajikistan and Uzbekistan, Radio Pakistan highlighted.

World leaders meet for climate talks, but big names missing

Dozens of world leaders convene in Azerbaijan for COP29 but many big names are skipping the UN climate talks where the impact of Donald Trump’s election victory is keenly felt.

UK’s Starmer will unveil an “ambitious” update to the UK’s climate goals later today, and said he wanted his country “to show leadership on the climate challenge.”

Joe Biden, Xi Jinping, Narendra Modi and Emmanuel Macron are among G20 leaders missing the event, where uncertainty over future US unity on climate action hung over the opening day.

“It’s not an ideal situation,” acknowledged Steven Guilbeault, Canada’s environment minister. “But in 30 years of COP, it’s not the first time that we’ve faced obstacles,” he told AFP.

“Certainly, everything is still possible.”

Washington’s top climate envoy John Podesta is seeking to reassure countries in Baku that Trump’s re-election will not end US efforts on global warming, even if the issue will be “on the back burner”.

But despite calls for global cooperation, the opening day got off to a rocky start, with feuds over the official agenda delaying by hours the start of formal proceedings in the stadium venue near the Caspian Sea.

“This will be a tough COP,” said Fernanda Carvalho, global climate and energy policy lead at WWF.

“Countries are divided. There is a lack of trust,” she told AFP, and divisions over climate finance “will be reflected in every room of those negotiations.”




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Is it really cheaper to cultivate your own fruit and vegetables?

Our gardening columnist James Wong isn’t convinced, and does the maths to get some answers




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A Comprehensive Guide to Long-Acting Injectable Antipsychotics for Primary Care Clinicians

We propose a paper that provides education on commonly used long-acting injectable antipsychotics (LAIs) to improve primary care based mental health interventions in patients with severe mental illnesses (SMIs) such as schizophrenia, schizoaffective disorder, and bipolar disorders. With the expanding interface of primary care and psychiatry across all healthcare settings, it has become increasingly important for primary care clinicians to have a broader understanding of common psychiatric treatments, including LAIs. Long-acting injectable antipsychotics have been shown to be helpful in significantly improving treatment adherence, preventing disease progression, improving treatment response, decreasing readmission rates, and reducing social impairment. We discuss evidence-based indications and guidelines for use of long-acting injectable antipsychotics. We provide an overview of the treatment of SMI with LAIs, mainly focusing on the most commonly used long-acting injectable antipsychotics, advantages and disadvantages of each, along with outlining important clinical pearls for ease of practical application. Equipped with increased familiarity and understanding of these essential therapies, primary care clinicians can better facilitate early engagement with psychiatric care, promote more widespread use, and thus significantly improve the wellbeing and quality of life of patients with severe mental illness.




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lncRNA BC200 is processed into a stable Alu monomer [ARTICLE]

The noncoding RNA BC200 is elevated in human cancers and is implicated in translation regulation as well as cell survival and proliferation. Upon BC200 overexpression, we observed correlated expression of a second, smaller RNA species. This RNA is expressed endogenously and exhibits cell-type-dependent variability relative to BC200. Aptamer-tagged expression constructs confirmed that the RNA is a truncated form of BC200, and sequencing revealed a modal length of 120 nt; thus, we refer to the RNA fragment as BC120. We present a methodology for accurate and specific detection of BC120 and establish that BC120 is expressed in several normal human tissues and is also elevated in ovarian cancer. BC120 exhibits remarkable stability relative to BC200 and is resistant to knockdown strategies that target the 3' unique sequence of BC200. Combined knockdown of BC200 and BC120 exhibits greater phenotypic impacts than knockdown of BC200 alone, and overexpression of BC120 negatively impacts translation of a GFP reporter, providing insight into a potential translational regulatory role for this RNA. The presence of a novel, truncated, and stable form of BC200 adds complexity to the investigation of this noncoding RNA that must be considered in future studies of BC200 and other related Alu RNAs.




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[18F]AlF-NOTA-FAPI-04 PET/CT for Predicting Pathologic Response of Resectable Esophageal Squamous Cell Carcinoma to Neoadjuvant Camrelizumab and Chemotherapy: A Phase II Clinical Trial

This single-center, single-arm, phase II trial (ChiCTR2100050057) investigated the ability of 18F-labeled fibroblast activation protein inhibitor ([18F]AlF-NOTA-FAPI-04, denoted as 18F-FAPI) PET/CT to predict the response to neoadjuvant camrelizumab plus chemotherapy (nCC) in locally advanced esophageal squamous cell carcinoma (LA-ESCC). Methods: This study included 32 newly diagnosed LA-ESCC participants who underwent 18F-FAPI PET/CT at baseline, of whom 23 also underwent scanning after 2 cycles of nCC. The participants underwent surgery after 2 cycles of nCC. Recorded PET parameters included maximum, peak, and mean SUVs and tumor-to-background ratios (TBRs), metabolic tumor volume, and total lesion FAP expression. PET parameters were compared between patient groups with good and poor pathologic responses, and the predictive performance for treatment response was analyzed. Results: The good and poor response groups each included 16 participants (16/32, 50.0%). On 18F-FAPI PET/CT, the posttreatment SUVs were significantly lower in good responders than in poor responders, whereas the changes in SUVs with treatment were significantly higher (all P < 0.05). SUVmax (area under the curve [AUC], 0.87; P = 0.0026), SUVpeak (AUC, 0.89; P = 0.0017), SUVmean (AUC, 0.88; P = 0.0021), TBRmax (AUC, 0.86; P = 0.0031), and TBRmean (AUC, 0.88; P = 0.0021) after nCC were significant predictors of pathologic response to nCC, with sensitivities of 63.64%–81.82% and specificities of 83.33%–100%. Changes in SUVmax (AUC, 0.81; P = 0.0116), SUVpeak (AUC, 0.82; P = 0.0097), SUVmean (AUC, 0.81; P = 0.0116), and TBRmean (AUC, 0.74; P = 0.0489) also were significant predictors of the pathologic response to nCC, with sensitivities and specificities in similar ranges. Conclusion: 18F-FAPI PET/CT parameters after treatment and their changes from baseline can predict the pathologic response to nCC in LA-ESCC participants.




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Low-Field (64 mT) Portable MRI for Rapid Point-of-Care Diagnosis of Dissemination in Space in Patients Presenting with Optic Neuritis [CLINICAL PRACTICE]

BACKGROUND AND PURPOSE:

Low-field 64 mT portable brain MRI has recently shown diagnostic promise for MS. This study aimed to evaluate the utility of portable MRI (pMRI) in assessing dissemination in space (DIS) in patients presenting with optic neuritis and determine whether deploying pMRI in the MS clinic can shorten the time from symptom onset to MRI.

MATERIALS AND METHODS:

Newly diagnosed patients with optic neuritis referred to a tertiary academic MS center from July 2022 to January 2024 underwent both point-of-care pMRI and subsequent 3T conventional MRI (cMRI). Images were evaluated for periventricular (PV), juxtacortical (JC), and infratentorial (IT) lesions. DIS was determined on brain MRI per 2017 McDonald criteria. Test characteristics were computed by using cMRI as the reference. Interrater and intermodality agreement between pMRI and cMRI were evaluated by using the Cohen . Time from symptom onset to pMRI and cMRI during the study period was compared with the preceding 1.5 years before pMRI implementation by using Kruskal-Wallis with post hoc Dunn tests.

RESULTS:

Twenty patients (median age: 32.5 years [interquartile range {IQR}, 28–40]; 80% women) were included, of whom 9 (45%) and 5 (25%) had DIS on cMRI and pMRI, respectively. Median time interval between pMRI and cMRI was 7 days (IQR, 3.5–12.5). Interrater agreement was very good for PV (95%, = 0.89), and good for JC and IT lesions (90%, = 0.69 for both). Intermodality agreement was good for PV (90%, = 0.80) and JC (85%, = 0.63), and moderate for IT lesions (75%, = 0.42) and DIS (80%, = 0.58). pMRI had a sensitivity of 56% and specificity of 100% for DIS. The median time from symptom onset to pMRI was significantly shorter (8.5 days [IQR 7–12]) compared with the interval to cMRI before pMRI deployment (21 days [IQR 8–49], n = 50) and after pMRI deployment (15 days [IQR 12–29], n = 30) (both P < .01). Time from symptom onset to cMRI in those periods was not significantly different (P = .29).

CONCLUSIONS:

In patients with optic neuritis, pMRI exhibited moderate concordance, moderate sensitivity, and high specificity for DIS compared with cMRI. Its integration into the MS clinic reduced the time from symptom onset to MRI. Further studies are warranted to evaluate the role of pMRI in expediting early MS diagnosis and as an imaging tool in resource-limited settings.




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Witnesses Say Would-Be Organ Donor Started ‘Thrashing’ on the Table

BSIP/Universal Images Group via Getty

Disaster was averted at a Kentucky hospital when an ostensibly deceased organ donor began “thrashing” around in the operating theater, a preservationist tells NPR.

“He was moving around,” Natasha Miller recalled of the patient, whom NPR identified as Anthony Thomas “TJ” Hoover II. “He was crying visibly.”

The two surgeons assigned to the transplant naturally refused to go through with the procedure, which was reportedly scheduled to take place at Baptist Health Richmond Hospital in October 2021. But when her colleague called Kentucky Organ Donor Affiliates, which coordinated the harvest, Miller said the supervisor told them they “were going to do the case” and needed to “find another doctor.”

Read more at The Daily Beast.




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Could Mars become habitable with the help of glitter-like iron rods?

If we want to terraform the Red Planet to make it better able to host microbial life, tiny rods of iron and aluminium may be the answer




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Google tool makes AI-generated writing easily detectable

Google DeepMind has been using its AI watermarking method on Gemini chatbot responses for months – and now it’s making the tool available to any AI developer




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Video Friday: Robots Solving Table Tennis



Video Friday is your weekly selection of awesome robotics videos, collected by your friends at IEEE Spectrum robotics. We also post a weekly calendar of upcoming robotics events for the next few months. Please send us your events for inclusion.

ICRA@40: 23–26 September 2024, ROTTERDAM, NETHERLANDS
IROS 2024: 14–18 October 2024, ABU DHABI, UAE
ICSR 2024: 23–26 October 2024, ODENSE, DENMARK
Cybathlon 2024: 25–27 October 2024, ZURICH

Enjoy today’s videos!

Imbuing robots with “human-level performance” in anything is an enormous challenge, but it’s worth it when you see a robot with the skill to interact with a human on a (nearly) human level. Google DeepMind has managed to achieve amateur human-level competence at table tennis, which is much harder than it looks, even for humans. Pannag Sanketi, a tech-lead manager in the robotics team at DeepMind, shared some interesting insights about performing the research. But first, video!

Some behind the scenes detail from Pannag:

  • The robot had not seen any participants before. So we knew we had a cool agent, but we had no idea how it was going to fare in a full match with real humans. To witness it outmaneuver even some of the most advanced players was such a delightful moment for team!
  • All the participants had a lot of fun playing against the robot, irrespective of who won the match. And all of them wanted to play more. Some of them said it will be great to have the robot as a playing partner. From the videos, you can even see how much fun the user study hosts sitting there (who are not authors on the paper) are having watching the games!
  • Barney, who is a professional coach, was an advisor on the project, and our chief evaluator of robot’s skills the way he evaluates his students. He also got surprised by how the robot is always able to learn from the last few weeks’ sessions.
  • We invested a lot in remote and automated 24x7 operations. So not the setup in this video, but there are other cells that we can run 24x7 with a ball thrower.
  • We even tried robot-vs-robot, i.e. 2 robots playing against each other! :) The line between collaboration and competition becomes very interesting when they try to learn by playing with each other.

[ DeepMind ]

Thanks, Heni!

Yoink.

[ MIT ]

Considering how their stability and recovery is often tested, teaching robot dogs to be shy of humans is an excellent idea.

[ Deep Robotics ]

Yes, quadruped robots need tow truck hooks.

[ Paper ]

Earthworm-inspired robots require novel actuators, and Ayato Kanada at Kyushu University has come up with a neat one.

[ Paper ]

Thanks, Ayato!

Meet the AstroAnt! This miniaturized swarm robot can ride atop a lunar rover and collect data related to its health, including surface temperatures and damage from micrometeoroid impacts. In the summer of 2024, with support from our collaborator Castrol, the Media Lab’s Space Exploration Initiative tested AstroAnt in the Canary Islands, where the volcanic landscape resembles the lunar surface.

[ MIT ]

Kengoro has a new forearm that mimics the human radioulnar joint giving it an even more natural badminton swing.

[ JSK Lab ]

Thanks, Kento!

Gromit’s concern that Wallace is becoming too dependent on his inventions proves justified, when Wallace invents a “smart” gnome that seems to develop a mind of its own. When it emerges that a vengeful figure from the past might be masterminding things, it falls to Gromit to battle sinister forces and save his master… or Wallace may never be able to invent again!

[ Wallace and Gromit ]

ASTORINO is a modern 6-axis robot based on 3D printing technology. Programmable in AS-language, it facilitates the preparation of classes with ready-made teaching materials, is easy both to use and to repair, and gives the opportunity to learn and make mistakes without fear of breaking it.

[ Kawasaki ]

Engineers at NASA’s Jet Propulsion Laboratory are testing a prototype of IceNode, a robot designed to access one of the most difficult-to-reach places on Earth. The team envisions a fleet of these autonomous robots deploying into unmapped underwater cavities beneath Antarctic ice shelves. There, they’d measure how fast the ice is melting — data that’s crucial to helping scientists accurately project how much global sea levels will rise.

[ IceNode ]

Los Alamos National Laboratory, in a consortium with four other National Laboratories, is leading the charge in finding the best practices to find orphaned wells. These abandoned wells can leak methane gas into the atmosphere and possibly leak liquid into the ground water.

[ LANL ]

Looks like Fourier has been working on something new, although this is still at the point of “looks like” rather than something real.

[ Fourier ]

Bio-Inspired Robot Hands: Altus Dexterity is a collaboration between researchers and professionals from Carnegie Mellon University, UPMC, the University of Illinois and the University of Houston.

[ Altus Dexterity ]

PiPER is a lightweight robotic arm with six integrated joint motors for smooth, precise control. Weighing just 4.2kg, it easily handles a 1.5kg payload and is made from durable yet lightweight materials for versatile use across various environments. Available for just $2,499 USD.

[ AgileX ]

At 104 years old, Lilabel has seen over a century of automotive transformation, from sharing a single car with her family in the 1920s to experiencing her first ride in a robotaxi.

[ Zoox ]

Traditionally, blind juggling robots use plates that are slightly concave to help them with ball control, but it’s also possible to make a blind juggler the hard way. Which, honestly, is much more impressive.

[ Jugglebot ]




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Video Friday: Jumping Robot Leg, Walking Robot Table



Video Friday is your weekly selection of awesome robotics videos, collected by your friends at IEEE Spectrum robotics. We also post a weekly calendar of upcoming robotics events for the next few months. Please send us your events for inclusion.

ICRA@40: 23–26 September 2024, ROTTERDAM, NETHERLANDS
IROS 2024: 14–18 October 2024, ABU DHABI, UAE
ICSR 2024: 23–26 October 2024, ODENSE, DENMARK
Cybathlon 2024: 25–27 October 2024, ZURICH

Enjoy today’s videos!

Researchers at the Max Planck Institute for Intelligent Systems and ETH Zurich have developed a robotic leg with artificial muscles. Inspired by living creatures, it jumps across different terrains in an agile and energy-efficient manner.

[ Nature ] via [ MPI ]

Thanks, Toshi!

ETH Zurich researchers have now developed a fast robotic printing process for earth-based materials that does not require cement. In what is known as “impact printing,” a robot shoots material from above, gradually building a wall. On impact, the parts bond together, and very minimal additives are required.

[ ETH Zurich ]

How could you not be excited to see this happen for real?

[ arXiv paper ]

Can we all agree that sanding, grinding, deburring, and polishing tasks are really best done by robots, for the most part?

[ Cohesive Robotics ]

Thanks, David!

Using doors is a longstanding challenge in robotics and is of significant practical interest in giving robots greater access to human-centric spaces. The task is challenging due to the need for online adaptation to varying door properties and precise control in manipulating the door panel and navigating through the confined doorway. To address this, we propose a learning-based controller for a legged manipulator to open and traverse through doors.

[ arXiv paper ]

Isaac is the first robot assistant that’s built for the home. And we’re shipping it in fall of 2025.

Fall of 2025 is a long enough time from now that I’m not even going to speculate about it.

[ Weave Robotics ]

By patterning liquid metal paste onto a soft sheet of silicone or acrylic foam tape, we developed stretchable versions of conventional rigid circuits (like Arduinos). Our soft circuits can be stretched to over 300% strain (over 4x their length) and are integrated into active soft robots.

[ Science Robotics ] via [ Yale ]

NASA’s Curiosity rover is exploring a scientifically exciting area on Mars, but communicating with the mission team on Earth has recently been a challenge due to both the current season and the surrounding terrain. In this Mars Report, Curiosity engineer Reidar Larsen takes you inside the uplink room where the team talks to the rover.

[ NASA ]

I love this and want to burn it with fire.

[ Carpentopod ]

Very often, people ask us what Reachy 2 is capable of, which is why we’re showing you the manipulation possibilities (through teleoperation) of our technology. The robot shown in this video is the Beta version of Reachy 2, our new robot coming very soon!

[ Pollen Robotics ]

The Scalable Autonomous Robots (ScalAR) Lab is an interdisciplinary lab focused on fundamental research problems in robotics that lie at the intersection of robotics, nonlinear dynamical systems theory, and uncertainty.

[ ScalAR Lab ]

Astorino is a 6-axis educational robot created for practical and affordable teaching of robotics in schools and beyond. It has been created with 3D printing, so it allows for experimentation and the possible addition of parts. With its design and programming, it replicates the actions of #KawasakiRobotics industrial robots, giving students the necessary skills for future work.

[ Astorino ]

I guess fish-fillet-shaping robots need to exist because otherwise customers will freak out if all their fish fillets are not identical, or something?

[ Flexiv ]

Watch the second episode of the ExoMars Rosalind Franklin rover mission—Europe’s ambitious exploration journey to search for past and present signs of life on Mars. The rover will dig, collect, and investigate the chemical composition of material collected by a drill. Rosalind Franklin will be the first rover to reach a depth of up to two meters below the surface, acquiring samples that have been protected from surface radiation and extreme temperatures.

[ ESA ]




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Do Newfoundland's Tablelands hold the answer to life on Mars? This researcher is trying to find out

The Tablelands in Gros Morne National Park, a UNESCO World Heritage Site, is one of the most unique landscapes in the world — and its orange peridotite rocks could hold the secret to finding life on Mars.



  • Radio/The Current



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‘Game Changer’ teaser: Ram Charan is ‘unpredictable’ in Shankar’s political actioner

‘Game Changer’ also stars Kiara Advani, Anjali, Samuthirakani, SJ Suryah, Srikanth and Sunil





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Now on-demand: Ars’ online IT roundtable on navigating 2020 schadenfreude

Replay our October 15 chat on, “Finding certainty in IT when the world is uncertain.”




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Ars online IT roundtable: What’s the future of the data center?

Join Sean Gallagher, Dell's Ivan Nekrasov, and me today, January 21, at 3:15pm Eastern!




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The coffee table book of Apple Music's Best 100 Albums will set you back $450

Apple has a history of eye-popping price tags, but the company is reaching new heights with a product that isn't even a gadget. After Apple Music unveiled a list of the 100 best albums of all time earlier this year, the streaming service is releasing a companion coffee table book. You can grab one of the 1,500 copies for a cool $450.

I find these endeavors to rank and quantify art hilarious, because music is subjective and personal by nature. But people do love to debate their own artistic opinions, so if that's your jam there's plenty to dig into with Apple Music's assessment. (And before you ask, the top spot was claimed by The Miseducation of Lauryn Hill.) This particular countdown was assembled by "Apple Music’s team of experts alongside an exclusive group of artists including Maren Morris, Pharrell Williams, J Balvin, Charli XCX, Mark Hoppus, Honey Dijon and Nia Archives, as well as songwriters, producers and industry professionals," according to the book listing.

I'm sure this limited-run hardcover will be very beautiful, and maybe the liner notes analyzing each entry are deeply insightful. But I also wonder who would bother to buy it. If you are one of those 1,500 people who wants one, the book is due to start shipping in January.

This article originally appeared on Engadget at https://www.engadget.com/entertainment/music/the-coffee-table-book-of-apple-musics-best-100-albums-will-set-you-back-450-193018825.html?src=rss




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Le comptable disparu de Saint-Jean-sur-Richelieu aurait été assassiné

Un mois après la mystérieuse disparition d’un comptable sans histoire de Saint-Jean-sur-Richelieu, le corps de l’homme de 68 ans a été retrouvé.




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Deux femmes redoutables au service de Donald Trump

Donald Trump va nommer la représentante Elise Stefanik, républicaine du nord de l’État de New York, ambassadrice des États-Unis à l’ONU.




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DoP rejects Aristo Pharma's review application for its multivitamin tablets

The Department of Pharmaceuticals (DoP) has upheld the retail price fixation of National Pharmaceutical Pricing Authority (NPPA) for Mumbai─based Aristo Pharmaceuticals for its multivitamin tablets with




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SEC recommends marketing approval for Dr Reddy's SPMS drug Siponimod tablets

The Subject Expert Committee (SEC), which advises the national drug regulator on approval of new drugs and clinical trials, has recommended grant of market authorisation for Dr Reddy's Laboratories' Siponimod




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Extending the Patentable Life of 3D Printers: A Lesson From the Pharmaceutical Industry

Modern innovation typically occurs one step-improvement at a time. Some clients initially question whether their new application of an existing technology is patentable. Usually, the answer is ‘yes.’ Under U.S. law (and most other jurisdictions), an innovation to an existing technology is patentable so long as at least one claim limitation is novel and non-obvious....… Continue Reading




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McDonald's E. coli crisis reveals why vegetable contamination is harder problem than tainted beef

NEW YORK – Moves by major US fast-food chains to temporarily scrub fresh onions off their menus on Oct 24, after the vegetable was named as the likely source of an E. coli outbreak at McDonald’s, laid bare the recurring nightmare for restaurants: Produce is a bigger problem for restaurants to keep free of contamination than beef. Onions are likely the culprit in the McDonald’s E. coli outbreak across the Midwest and some Western states that has sickened 49 people and killed one, the US Department of Agriculture said late on Oct 23. The company pulled the Quarter Pounder off its menu at one-fifth of its 14,000 US restaurants. In past years, beef patties dominated the dockets of food-borne-illness lawyers, before US federal health regulators cracked down on beef contamination after an E. coli outbreak linked to Jack in the Box burgers hospitalised more than 170 people across states and killed four. As a result, beef-related outbreaks became much rarer, experts say.




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Data | Andheri East: Not a NOTA notable, just a blip amid falling vote shares

NOTA continues to be salient in Naxalite areas, but its share has fallen in recent elections




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H-Diplo|RJISSF Roundtable 15-26 on Hazelton, Bullets not Ballots

Jacqueline L. Hazelton's Bullets not Ballots: Success in Counterinsurgency Warfare (Cornell University Press, 2021) is the subject of a Roundtable Review.




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Event Debrief: Advancing Equitable Clean Technology Investment Through the Greenhouse Gas Reduction Fund

Harvard Kennedy School hosted Jahi Wise, Senior Adviser to the Administrator of the U.S. Environmental Protection Agency, to discuss the design and implementation of the Greenhouse Gas Reduction Fund, a historic investment in American clean energy technology finance.






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Ondori Asian Kitchen, A Delectable Duality of Chinese and Japanese Cuisines, Now Open at The Orleans - Ondori Asian Kitchen

Special guests helped celebrate the opening of Ondori Asian Kitchen, a distinctive new dining concept at The Orleans Hotel and Casino, on March 2, 2016.




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Laura Dern, Kellie Pickler, Valerie Harper Among Notable Voices Kicking Off National Women's Lung Health Week - #ShareYourVoice for LUNG FORCE

Laura Dern, Kellie Pickler, Valerie Harper Among Notable Voices Kicking Off National Women�s Lung Health Week




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Board-certified Plastic Surgeons Discuss Best Practices For Facial Rejuvenation At The Aesthetic Meeting Of The American Society For Aesthetic Plastic Surgery - Facial Rejuvenation with Injectables

Tailoring Anti-Aging Treatments To Patients' Needs





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Gout & Uric Acid Education Society Hosts Roundtable Exploring Strategies for Elevating the Severity of Gout and Improving Access to Public Education and Treatment - Gout as a Serious Health Issue

Gout as a Serious Health Issue




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One of the Top Infectious Diseases Among Children in the U.S. is Preventable - Help Kids Defeat the Mouth Monsters

Help Kids Defeat the Mouth Monsters




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CBIC Revises Notification No. 36/2001 with New Tables

Government of IndiaMinistry of FinanceDepartment of RevenueCentral Board of Indirect Taxes and CustomsNotification No. 73/2024-CUSTOMS (N.T.)New Delhi, 30th October, 202408 Kartika,1946 (SAKA)S.O. .




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2 ways we’re helping students build more equitable tech

Our new online platform and summit will help students learn more about product inclusion and equity.



  • Learning & Education
  • Diversity and Inclusion

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Amazon Children's Day Sale 2024: Get Massive Discounts on Best Android Tablets for E-Learning

Amazon's Children's Day Store is now open, featuring an array of products specially discounted for the occasion, including top-selling Android tablets ideal for e-learning. With price reductions of up to 75% on select items such as headphones, tablets, and kids' smartwatches,




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November 10, 2024: The Reality Of Tariffs In Tabletop Gaming

Over the next few weeks and months, you'll see social media posts discussing how companies cannot offer holiday bonuses or will have to cut employees due to Trump's tariffs (proposed or enacted).

 

Some of these stories may be fiction or cautionary tales that illustrate the price the average American pays for a politician's decision.

 

But I can 100% tell you this is a reality many business owners in the manufacturing sector now face.

 

If you aren't aware of how tariffs work, it's relatively simple. The company importing the goods from a foreign country pays the fee. If a company has to pay 20%, 60%, or 200% more to bring that item into the United States, who ultimately bears that cost? The American people.

 

Over the last few days, I have been talking at length with my factory representatives, figuring out how much of an item I need to order now to offset any expanded costs later. In addition, we are looking at where we can move manufacturing to outside of China (hard mode, not a lot of places outside of China or Europe produce boardgame components at the scale our industry uses).

 

I've been speaking with my shipping representatives about the increasing freight costs we expect to see with a rise in tariffs. We're already paying extreme freight prices, which will only go up as demand increases. The last time tariffs were levied on Chinese manufactured goods, freight costs went up.

 

Now I am in a position that forces me to examine how much we may need to raise prices if the most extreme of the proposed tariffs goes into effect.

 

I'm also trying to do right by my staff. But I can only do so much, you know? How long can business owners incur these costs, protect our staff, and not have consumers pay through the nose? Can I accept breaking even for the time being to keep my people employed and our games affordable? But what happens when the company starts losing money?

 

Many CEOs and business owners are staring down this reality right now. This isn't just a theoretical exercise. We have to plan for the worst.

 

So, what do I plan to do about this? I will be even more present in my local and state business associations that have direct links to policy makers in D.C. I will take every opportunity to speak directly to those who have a say in this new administration about why this isn't good for the economy. I'm just a tiny player in the world of manufacturing. But I do know the power of my voice. And more importantly, I know the power your voice holds as well.

 

You can start putting pressure on your elected (or newly elected) officials by writing, calling, or contacting them through their open channels (many of them love social media). Tell them you do not want these proposed tariffs, and let them know how these cost increases will impact you. Hold them to their promises. Make your voice heard. 

We are all in this together. 


Meredith Placko

Warehouse 23 News: A Great Deal Of Adventure!

Excitement is in the cards with the Decks of Destiny for The Fantasy Trip. This collection of resources and reference material contains adversaries, rumors, combat options, and more to make your games of TFT fast and furious. Download this set today from Warehouse 23!




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Google tool makes AI-generated writing easily detectable

Google DeepMind has been using its AI watermarking method on Gemini chatbot responses for months – and now it’s making the tool available to any AI developer




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25 Cool Cats Who Would Not Be Caught Dead Sitting Anywhere Other Than the Popular People's Table

There is little denying that if animals were to go to school, cats would be the cool kids. They are sassy enough, facetious enough, cliquey enough and most definitely cool enough to hold their prestigious pawsition. So we decided it would be rather confidence boosting to live vicariously through these trendsetting sweethearts to give you some much-needed comfort and confidence as you slip and slide towards the work week. Which is why we made this list of cool cats who would not be caught dead sitting anywhere other than the popular people's table. Make sure only share this list with other feline fanatics, unless you want some kooky canine connoisseur sitting at your table this week.

From the out of control cats who have used their positions of power and influence to start their own religions, to the fur-iously friendly feline who makes a point of getting all the pets from passers by, to the crafty catto who knows the value of a little lie when it comes to getting extra food.