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Viewpoints: Donald Trump Denies Existence of Climate Change

Donald Trump has claimed he doesn't believe in climate change, but that didn't stop him from citing it as a reason to build a sea wall to protect one of his golf courses.




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Viewpoints: How Accurate Are the U.S. Election Polls?

Not a second goes by without pundits and the media scrutinizing the U.S. election polls and tracking the candidates' performances. But polls aren't votes. What if the polls are all wrong?




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Somalia President Appoints New Military Commanders

[Shabelle] Mogadishu -- In a strategic move to bolster Somalia's defense apparatus, President Hassan Sheikh Mohamud has made key changes in the military hierarchy, appointing General Sahal Abdullahi Omar as the new Commander of Land Forces and elevating Lt. Colonel Hassan Salah Abdi to the position of Commander of Special Forces.




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Somalia's Cabinet Appoints Odowa Yusuf Raage to Lead National Army Against Al-Shabaab

[Shabelle] Mogadishu, Somalia -- In a decisive move to strengthen national security, Somalia's Cabinet of Ministers has officially endorsed General Odowa Yusuf Raage as the Commander of the Somali National Army, according to a statement released after an emergency meeting held on Sunday night.




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Somalia Reappoints Gen Odawaa As Army Chief Amid Push Against Al-Shabaab

[Radio Dalsan] The Somali Council of Ministers has reappointed General Odowa Yusuf Raage as Commander of the Somali Armed Forces, replacing General Ibrahim Muhyiddin, during an emergency meeting held in Mogadishu on Sunday night.




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Trump to appoint hardliners Rubio and Waltz as foreign policy chiefs, reports claim

Trump to appoint hardliners Rubio and Waltz as foreign policy chiefs, reports claim




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The Point of the Parable of the Vineyard

Jesus made a regular habit of upending established social conventions. The Lord spent much of His earthly ministry illustrating the sharp contrast between the world and His heavenly kingdom. One of those key teaching moments is found in the preface and epilogue to Christ’s parable of the vineyard.

READ MORE




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UK regular pay grows at slowest pace in two years, pointing to lower inflation

British wage growth excluding bonuses fell in the third quarter to its lowest in over two years, official data showed on Tuesday, potentially boosting the Bank of England’s confidence that inflation pressures will continue to ease. Average weekly earnings, excluding bonuses, were 4.8 per cent higher in the three months to the end of September […]




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to wow with powerpoint richard harrington

to wow with powerpoint richard harrington




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Why criticisms of the proposed Anthropocene epoch miss the point

A proposal to define the Anthropocene as a geological epoch was rejected this March, but humanity's impact on Earth is real, whether formalised or not, says Jan Zalasiewicz




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The Amazon is teetering on the edge of a climate tipping point

In some recent years, the Amazon biome released more carbon than it absorbed, and further degradation could make it a permanent shift




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Study Points to Cause of Vioxx Heart Risk

Title: Study Points to Cause of Vioxx Heart Risk
Category: Health News
Created: 8/28/2007 2:00:00 AM
Last Editorial Review: 8/28/2007 12:00:00 AM




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Scientists Pinpoint Source of Mercury in Pacific Ocean Fish

Title: Scientists Pinpoint Source of Mercury in Pacific Ocean Fish
Category: Health News
Created: 8/26/2013 9:35:00 AM
Last Editorial Review: 8/26/2013 12:00:00 AM




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Impact of Point of Care Hemoglobin A1c Testing on Time to Therapeutic Intervention

Without compromising accuracy, point of care testing (POCT) provides immediate results at the time of in person patient consultation. The purpose of this study was to evaluate time until therapeutic intervention with POCT HbA1c versus venipuncture, where venipuncture was considered standard of care.

The primary outcome was time (hours) to implementation of a therapeutic intervention based on POCT HbA1c result, as compared with most recent venipuncture HbA1c before the study and its associated therapeutic intervention. A total of 94 POCT HbA1c tests were included in the primary analysis.

For the POCT HbA1c, the mean time to therapeutic intervention was 1.6 ± 3.14 hours. For the previous venipuncture HbA1c, the mean time to therapeutic intervention was 1376.66 ± 3356.6 hours (P < .001). Overall, this trial showed that POCT HbA1c results in a significantly faster time to therapeutic intervention than venipuncture in a primary care clinic that serves a rural population.




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The Dawning of a New Age of Preclinical Analgesic Drug Screening [Viewpoint]




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Minor Cannabinoids as an Emerging Frontier for Pain Relief [Viewpoint]




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Low-Field (64 mT) Portable MRI for Rapid Point-of-Care Diagnosis of Dissemination in Space in Patients Presenting with Optic Neuritis [CLINICAL PRACTICE]

BACKGROUND AND PURPOSE:

Low-field 64 mT portable brain MRI has recently shown diagnostic promise for MS. This study aimed to evaluate the utility of portable MRI (pMRI) in assessing dissemination in space (DIS) in patients presenting with optic neuritis and determine whether deploying pMRI in the MS clinic can shorten the time from symptom onset to MRI.

MATERIALS AND METHODS:

Newly diagnosed patients with optic neuritis referred to a tertiary academic MS center from July 2022 to January 2024 underwent both point-of-care pMRI and subsequent 3T conventional MRI (cMRI). Images were evaluated for periventricular (PV), juxtacortical (JC), and infratentorial (IT) lesions. DIS was determined on brain MRI per 2017 McDonald criteria. Test characteristics were computed by using cMRI as the reference. Interrater and intermodality agreement between pMRI and cMRI were evaluated by using the Cohen . Time from symptom onset to pMRI and cMRI during the study period was compared with the preceding 1.5 years before pMRI implementation by using Kruskal-Wallis with post hoc Dunn tests.

RESULTS:

Twenty patients (median age: 32.5 years [interquartile range {IQR}, 28–40]; 80% women) were included, of whom 9 (45%) and 5 (25%) had DIS on cMRI and pMRI, respectively. Median time interval between pMRI and cMRI was 7 days (IQR, 3.5–12.5). Interrater agreement was very good for PV (95%, = 0.89), and good for JC and IT lesions (90%, = 0.69 for both). Intermodality agreement was good for PV (90%, = 0.80) and JC (85%, = 0.63), and moderate for IT lesions (75%, = 0.42) and DIS (80%, = 0.58). pMRI had a sensitivity of 56% and specificity of 100% for DIS. The median time from symptom onset to pMRI was significantly shorter (8.5 days [IQR 7–12]) compared with the interval to cMRI before pMRI deployment (21 days [IQR 8–49], n = 50) and after pMRI deployment (15 days [IQR 12–29], n = 30) (both P < .01). Time from symptom onset to cMRI in those periods was not significantly different (P = .29).

CONCLUSIONS:

In patients with optic neuritis, pMRI exhibited moderate concordance, moderate sensitivity, and high specificity for DIS compared with cMRI. Its integration into the MS clinic reduced the time from symptom onset to MRI. Further studies are warranted to evaluate the role of pMRI in expediting early MS diagnosis and as an imaging tool in resource-limited settings.




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RPG Cast – Episode 612: “He Must Have Put Skill Points Into Broom Handle”

Josh demands justice for Jorts. Chris is deployed to the circus wars. And Kelley assures us that Fang sniper is real. We'll see you in 2022. Don't butter your cats!

The post RPG Cast – Episode 612: “He Must Have Put Skill Points Into Broom Handle” appeared first on RPGamer.




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Rogue Point is a door-kicking co-op shooter from Black Mesa studio

The developers who remade Half-Life as Black Mesa are working on a new roguelite co-op shooter. It will feature no physicists celebrating Bring Your Shotgun To Work Day, but instead let up to four players tactically breach oil rigs and airports occupied by corporate-sponsored mercenaries. In Rogue Point the richest CEO on earth has croaked it, causing various megacorps to compete in a violent bum rush for control of that wealth. Which is where your team of renegade shooterists come in. They don't want to win this contest, they just want everyone else to lose.

Read more




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Critics of the International Space Station are missing the point

As the International Space Station comes to the end of its life, we should recognise its biggest achievement – showing that a better world is possible




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AI can predict tipping points for systems from forests to power grids

Combining two neural networks has helped researchers predict potentially disastrous collapses in complex systems, such as financial crashes or power blackouts




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Gary Lineker replacement decided as BBC tipped for rogue MOTD appointment



Express Sport writers have decided who should replace Gary Lineker




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Sony's PS5 Pro comes with a secret feature for PlayStation fans but it may disappoint



Aside from offering a more powerful console, the PS5 Pro also packs a sneaky theme for PlayStation fans to uncover - something Sony hadn't previously discussed.




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Trump appoints Musk, Ramaswamy to lead Department of Government Efficiency

President-elect Donald Trump on Tuesday announced that Tesla founder Elon Musk and businessman Vivek Ramaswamy will a new Department of Government Efficiency, a White House office given the task of cutting the federal budget.





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Evidence points to Wuhan market as source of covid-19 outbreak

Genetic testing on samples collected during the earliest days of the covid-19 outbreak suggests it is likely that the virus spread from animals to humans at the Huanan seafood market





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Identity, Endpoint, and Network Security Walk into a Bar

With a macrotrend/backdrop of platformization and convergence, the industry is exploring places where identity security, endpoint security, and network security naturally meet.

The post Identity, Endpoint, and Network Security Walk into a Bar appeared first on Gigaom.




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The Dow Jones soars over 1,500 points to record high after Trump wins the election

Wall Street, crypto investors, and shareholders in Trump Media are all cheering the election results.




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Meta Quest 3S is a disappointing half-step to Carmack’s low-cost VR vision

Significant visual and comfort compromises make last year's Quest 3 a better VR investment.





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Mystery of blobs washing up on Newfoundland's beaches solved, as scientists pinpoint chemical

Throughout the fall, unusual white blobs have been washing ashore on beaches in eastern Newfoundland. A Memorial University chemist says the substance is a type of pollution that shouldn't have been in the ocean in the first place.



  • News/Canada/Nfld. & Labrador

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Donald Trump Doesn’t Need Recess Appointments

And the Senate shouldn’t abandon its ‘advice and consent’ role.




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Rogue Point is a tactical shooter from the teams behind Worms and Black Mesa

Team17, the developer of the Worms and publisher of Dredge, Blasphemous and more, is working on Rogue Point, a new rogue-lite tactical FPS game. The studio has enlisted the help of Crowbar Collective, the team behind Black Mesa, the fan-made and Valve-approved Half-Life remake that needs no further introduction. Rogue Point is currently in development and slated to enter early access soon.

Rogue Point is set in a dystopian future where a single CEO had controlled everything. After his death, competing companies work to carve up his empire. To achieve this, they hire mercenaries using the MERX app, and it’s as simple as getting food using Uber Eats. Currently, only Rogue Point, a team of vigilantes, is fighting back against this dystopian state of affairs.

Team17/Crowbar Collective

The game pits teams of four against computer-controlled enemies of different classes, each offering unique challenges. Players must strategize and play with the right loadouts or risk losing. There’s plenty of gear to acquire, too, with some weapons only available in the mission field.

Maps are procedurally generated to ensure no two playthroughs are the same. Unlocked equipment may also be used in future runs. Besides the standard campaign missions where “high-octane tactical combat meets strategic planning,” there’s an endgame mission with maxed-out difficulty, promising a challenge for those craving it.

The developers have a rather extensive wishlist of features they hope to add to the game down the road. Those include new weapons (who doesn’t like new gear?), improved AI and new maps. There are currently four maps announced, but the procedural generation should make things less repetitive.

Rogue Point isn’t in early access yet, but you can wishlist it on Steam. The game is set to come out in 2025, but the developers have yet to announce a final release date.

This article originally appeared on Engadget at https://www.engadget.com/gaming/pc/rogue-point-is-a-tactical-shooter-from-the-teams-behind-worms-and-black-mesa-142959920.html?src=rss




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Secret tape not the only talking point

THE reasons behind a decision to release a secret expletive-laden recording of former Chief Justice Tim Carmody are almost as juicy as the tape is expected to be.




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New Minister appointed

KOROROIT MP Marlene Kairouz will become Victoria’s new minister for consumer affairs, gambling and liquor regulation.




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Neuralink’s Blindsight Device Is Likely to Disappoint



Neuralink’s visual prosthesis Blindsight has been designated a breakthrough device by the U.S. Food and Drug Administration, which potentially sets the technology on a fast track to approval.

In confirming the news, an FDA spokesperson emphasized that the designation does not mean that Blindsight is yet considered safe or effective. Technologies in the program have potential to improve the current standard of care and are novel compared to what’s available on the market, but the devices still have to go through full clinical trials before seeking FDA approval.

Still, the announcement is a sign that Neuralink is moving closer to testing Blindsight in human patients. The company is recruiting people with vision loss for studies in the United States, Canada, and the United Kingdom.

Visual prostheses work by capturing visual information with a video camera, typically attached to glasses or a headset. Then a processor converts the data to an electrical signal that can be relayed to the nervous system. Retinal implants have been a common approach, with electrodes feeding the signal to nerves in the retina, at the back of the eye, from where it travels on to the brain. But Blindsight uses a brain implant to send the signal directly to neurons in the visual cortex.

In recent years, other companies developing artificial vision prosthetics have reached clinical research trials or beyond, only to struggle financially, leaving patients without support. Some of these technologies live on with new backing: Second Sight’s Orion cortical implant project is now in a clinical trial with Cortigent, and Pixium Vision’s Prima system is now owned by Science, with ex-Neuralink founder Max Hodak at the helm. No company has yet commercialized a visual prosthetic that uses a brain implant.

Elon Musk’s Claims About Blindsight

Very little information about Blindsight is publicly available. As of this writing, there is no official Blindsight page on the Neuralink website, and Neuralink did not respond to requests for comment. It’s also unclear how exactly Blindsight relates to a brain-computer interface that Neuralink has already implanted in two people with paralysis, who use their devices to control computer cursors.

Experts who spoke with IEEE Spectrum felt that, if judged against the strong claims made by Neuralink’s billionaire co-founder Elon Musk, Blindsight will almost certainly disappoint. However, some were still open to the possibility that Neuralink could successfully bring a device to market that can help people with vision loss, albeit with less dramatic effects on their sense of sight. While Musk’s personal fortune could help Blindsight weather difficulties that would end other projects, experts did not feel it was a guarantee of success.

After Neuralink announced on X (formerly Twitter) that Blindsight had received the breakthrough device designation, Musk wrote:

The Blindsight device from Neuralink will enable even those who have lost both eyes and their optic nerve to see.

Provided the visual cortex is intact, it will even enable those who have been blind from birth to see for the first time.

To set expectations correctly, the vision will be at first be [sic] low resolution, like Atari graphics, but eventually it has the potential be [sic] better than natural vision and enable you to see in infrared, ultraviolet or even radar wavelengths, like Geordi La Forge.

Musk included a picture of La Forge, a character from the science-fiction franchise Star Trek who wears a vision-enhancing visor.

Experts Puncture the Blindsight Hype

“[Musk] will build the best cortical implant we can build with current technology. It will not produce anything like normal vision. [Yet] it might produce vision that can transform the lives of blind people,” said Ione Fine, a computational neuroscientist at the University of Washington, who has written about the potential limitations of cortical implants, given the complexity of the human visual system. Fine previously worked for the company Second Sight.

A successful visual prosthetic might more realistically be thought of as assistive technology than a cure for blindness. “At best, we’re talking about something that’s augmentative to a cane and a guide dog; not something that replaces a cane and a guide dog,” said Philip Troyk, a biomedical engineer at the Illinois Institute of Technology.

Restoring natural vision is beyond the reach of today’s technology. But among Musks recent claims, Troyk says that a form of infrared sensing is plausible and has already been tested with one of his patients, who used it for help locating people within a room. That patient has a 400-electrode device implanted in the visual cortex as part of a collaborative research effort called the Intracortical Visual Prosthesis Project (ICVP). By comparison, Blindsight may have more than 1,000 electrodes, if it’s a similar device to Neuralink’s brain-computer interface.

Experts say they’d like more information about Neuralink’s visual prosthetic. “I’m leery about the fact that they are very superficial in their description of the devices,” said Gislin Dagnelie, a vision scientist at Johns Hopkins University who has been involved in multiple clinical trials for vision prosthetics, including a Second Sight retinal implant, and who is currently collaborating on the ICVP. “There’s no clear evaluation or pre-clinical work that has been published,” says Dagnelie. “It’s all based on: ‘Trust us, we’re Neuralink.’”

In the short term, too much hype could mislead clinical trial participants. It could also degrade interest in small but meaningful advancements in visual prosthetics. “Some of the [Neuralink] technology is exciting, and has potential,” said Troyk. “The way the messaging is being done detracts from that, potentially.”




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Data Point | Looking back at the contributions of Indian women leaders

The Data Point is a bi-weekly newsletter in which The Hindu’s Data team decodes the numbers behind today’s biggest stories.  








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New Survey Shows UK Public Willing to Pay �10 for Missed GP Appointments to Support the NHS Amid Widespread Concerns About Government Spending on Healthcare - Healthcare leaders and the public say how they would balance the NHSï¿

Healthcare leaders and the public say how they would balance the NHS� books




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CBIC Appoints New Customs Adjudication Authority in Mumbai

Government of IndiaMinistry of Finance(Central Board of Indirect and Customs)Notification[No.72/2024-Customs (N.T.)]New Delhi, the 2




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The Amazon is teetering on the edge of a climate tipping point

In some recent years, the Amazon biome released more carbon than it absorbed, and further degradation could make it a permanent shift




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Point of View

Dutch angles, get it




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Mother appoints her brother to be her 3 under 10-year-old children's unpaid personal chef: '[She] expect[s] me to make something every day for the kids'

Meals are undoubtedly one of the most important daily chores, along with sleep. Being properly fed is one of the things that everything else in a successful and happy life stems from. But providing healthy meals for your family isn't cheap… Have you seen the price of groceries these days? And the time it takes to cook and clean for an entire family can't be understated. So, undoubtedly, the combination of those two things, the time and the price of the actual food, would be supremely valuable. 

Of course, you can just trick your sous-chef brother into cooking for your three children instead. Surely, if he's willing to do it once for free, you can just ask him to do it again and again. Even when it comes to family, there's a limit to the favors you're expected to perform, and there's a point where demanding favors just becomes freeloading and entitlement




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High school English teacher docks 99 points from a student's grade by cleverly proving they used AI to write their assignment: ‘We both knew what they did’

It seems like the only way to prevent cheating in an age where we all have little computers in our pockets is to completely isolate a person, give them a pencil and some paper, and unleash their class assignment. But since we don't exist in a vacuum and high school classes have upwards of 30+ kids per 45-minute class period, you've got to be like this teacher in our next story, who was far more clever than that. 

Being a teacher in 2024 is probably one of the most challenging jobs. 

Teachers are overworked, under-appreciated, and likely underpaid for their version of professional cat-wrangling. Not only are the kids feral, but they're becoming far more witty to cut corners in class. However, wiley, lazy, and arrogant teenagers make the perfect target for a well-laid trap in the form of a hyper-specific creative writing assignment. 

Keep scrolling to read the satisfying tale of a cheater getting exposed for their lies and thrown to the wolves simply because they were too entitled to attempt their school assignment.




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Budget 2024: Key points at a glance

Chancellor Rachel Reeves has delivered Labour’s first Budget since 2010 – here’s what you need to know.