Ontario Premier Doug Ford says the Toronto Maple Leafs' parent company has been in contact with the province about the possibility of Canada's biggest city serving as a so-called "hockey pod" for teams should the NHL resume its season.

Montreal Canadiens goaltender Carey Price has reached out to give support to two boys who lost their parents during the Nova Scotia mass shooting last month.

Just when you thought you watched the best shot of the Brier, another best shot of the Brier appears at the 2020 Canadian men's curling championship being held in Kingston, Ont.

Avid curler Dale Kohlenberg, 64, got a lucky break when he was seconded to Iqaluit — and was quickly scouted for Team Nunavut.

Alberta's Brendan Bottcher defeated Saskatchewan's Matt Dunstone 9-4 in the 1-2 Page playoff game Saturday afternoon to earn a berth in the Tim Hortons Brier final.

The University of Alberta Pandas defeated the UNB Reds 10-2 in the U Sports women's curling final, while the Laurier Golden Hawks topped the Dalhousie Tigers 8-5 for the men's curling title in Portage la Prairie, Manitoba on Sunday.

The Kevin Koe curling team has split with second Colton Flasch after being eliminated from the recent men's national championship in Kingston, Ont., in a tiebreaker game. Flasch joined the foursome in 2018.

The bonspiel took place in Edmonton March 11-14, starting the same day COVID-19 was declared a global pandemic.

Colleen Jones, Sidney Crosby among many preeminent local sports figures reacting in the aftermath of Sunday's killing rampage.

The time was right for Lisa Weagle to join forces with Olympic champion Jennifer Jones. Jones told CBC Sports' Anastasia Bucsis that the latest addition to her five-person rink "was like the clouds parted and the sun came out."

He’s not rising to the challenge of the coronavirus pandemic. He’s shriveling into nothingness.

Join our Facebook live on Thursday at noon with Dr. Roselyn Wilson a psychiatrist at St. Joseph’s Healthcare Hamilton’s Youth Wellness Centre. She'll talk with us about how COVID-19 is heightening anxiety in some young people. We'll talk about how to help the young people in your life through the pandemic.

Flattening the curve has been so successful and two areas around Hamilton — Brant and Haldimand-Norfolk — haven't had a new case of COVID-19 in three days, and Burlington has only had two.

The province says no one has to tell others if they get COVID-19. The same goes for businesses or landlords, should employees or tenants get sick. But should you tell?

Government restrictions designed to limit the spread of COVID-19 have virtually crippled Ontario's wine-making industry, as retail and wholesale revenues dry up but the costs of producing wine remains constant.

Fears that COVID-19 would spread at the Hamilton-Wentworth Detention Centre appear not to have materialized — at least not yet.

Sofina Foods plants in Burlington and Mississauga have each had an employee test positive.

McMaster University is planning for fewer international students, more deferred acceptance offers and online teaching for the thousands who are attending as the start of a new school year looms in the near future and in the middle of the COVID-19 pandemic.

Determining the concentration of protein samples generally is accomplished either by measuring the UV absorbance at 280 nm or by reacting the protein quantitatively with dyes and/or metal ions (Bradford, Lowry, or BCA assays). For purified proteins, UV absorbance remains the most popular method because it is fast, convenient, and reproducible; it does not consume the protein; and it requires no additional reagents, standards, or incubations. No method of protein concentration determination is perfect because each is subject to a different set of constraints such as interference of buffer components and contaminating proteins in direct UV determination (A₂₈₀) or reactivity of individual proteins and buffer components with the detecting reagents in colorimetric assays. In cases in which protein concentration is critical (e.g., determination of catalytic rate constants for an enzyme), it may be advisable to compare the results of several assays.

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One of the main mechanisms of azole resistance of Aspergillus fumigatus is thought to be a reduction in the drug’s affinity for the target molecule, Cyp51A, due to its amino acid mutation(s). It is known that the azole resistance pattern is closely related to the mutation site(s) of the molecule. In this study, we tried to develop a simple and rapid detection method for cyp51A mutations using the endonuclease Surveyor nuclease. The Surveyor nuclease assay was verified using several azole-resistant strains of A. fumigatus that possess point mutations in Cyp51A. For validation of the Surveyor nuclease assay, blind tests were conducted using 48 strains of A. fumigatus (17 azole-resistant and 31 azole-susceptible strains). The Surveyor nuclease assay could rapidly detect cyp51A mutations with one primer set. Also, all the tested strains harboring different cyp51A single point mutations could be clearly distinguished from the wild type. The Surveyor nuclease assay is a simple method that can detect cyp51A mutations rapidly.

BCBS Press release "Basel Committee publishes stocktake report on climate-related financial risk initiatives'", 30 April 2020

Banks globally entered the Covid-19 crisis with roughly US$ 5 trillion of capital above their Pillar 1 regulatory requirements. The amount of additional lending will depend on how hard banks' capital is hit by the crisis, on their willingness to use the buffers and on other policy support. In an adverse stress scenario such as the savings and loan crisis, banks' usable buffers would decline to US$ 800 billion, which could support US$ 5 trillion of additional loans (6% of total loans outstanding). Yet in a severely adverse scenario, similar to the Great Financial Crisis, the corresponding figures would be only US$ 270 billion and US$ 1 trillion (1.3% of total loans).

Banks' performance on equity and debt markets since the Covid-19 outbreak has been on a par with that experienced after the collapse of Lehman Brothers in 2008. During the initial phase, the market sell-off swept over all banks, which underperformed significantly relative to other sectors. Still, markets showed some differentiation by bank nationality, and credit default swap (CDS) spreads rose the most for those banks that had entered the crisis with the highest level of credit risk. The subsequent stabilisation, brought about by forceful policy measures since mid-March, has favoured banks with higher profitability and healthier balance sheets. Less profitable banks saw their long-term rating outlooks revised to negative. And the CDS spreads of the riskiest banks continued increasing even through the stabilisation phase.

We document that corporate pension contributions respond to tax-based incentives using the 2017 Tax Cut & Jobs Act (TCJA) as a natural experiment. The TCJA cut the U.S. federal corporate tax rate, temporarily increasing contribution incentives for sponsors of defined-benefit retirement plans. We exploit cross-sectional variation in ex-ante exposure to these incentives.

Equities are likely to keep trading in volatile ranges until the many conflicting narratives in the market give way to a singular message for investors.

Information technology, health care, and consumer discretionary stocks that outperformed in the last decade have done well in the first four months of 2020.

Gold and silver prices often move in tandem, but the gap between them widened by 31% January through April in line with a trend that began nine years ago.

Bank of Finland Research Discussion Papers by Gonçalo Faria and Fabio Verona

Bank of England Working Papers by Nicola Garbarino and Benjamin Guin

European Central Bank Working Papers by Marien Ferdinandusse, Maximilian Freier and Annukka Ristiniemi

European Systemic Risk Board Occasional Papers by Greg Ros

Central Bank of Chile Working Papers by Andrés Sagner

Central Bank of Chile Working Papers by Tomás Gómez, Alejandro Jara and David Moreno

If you're willing to pay the (necessarily) big bucks to create a new TRX40-based Threadripper desktop, few motherboards on any platform can match the Asus ROG Zenith II Extreme for sheer robustness and feature set.

As the pols take the fight out back to the web, will the dank memes prevail?