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Assam is the second largest state (by area) in India's northeast region. It also has the largest population and the biggest economy amongst India's northeast states, contributing around 60% of the region's economy activity. The state's 2020/21 per capita gross state domestic product (GSDP) of INR 86,857 ranks it in the bottom quartile nationally.

Title: Is Graves’ Disease the Same as Thyrotoxicosis?
Category: Diseases and Conditions
Created: 7/8/2022 12:00:00 AM
Last Editorial Review: 7/8/2022 12:00:00 AM

Title: Heart Risks the Same With 2 Diabetes Drugs: Study
Category: Health News
Created: 8/24/2010 6:10:00 PM
Last Editorial Review: 8/25/2010 12:00:00 AM

Title: China Withholding H7N9 Bird Flu Virus Samples From U.S.
Category: Health News
Created: 8/31/2018 12:00:00 AM
Last Editorial Review: 8/31/2018 12:00:00 AM

Title: Whether From Diet or Surgery, Weight Loss Has Same Benefits: Study
Category: Health News
Created: 8/21/2020 12:00:00 AM
Last Editorial Review: 8/24/2020 12:00:00 AM

Title: Cheap, Same-Day Test Could Help Spot Miscarriage Risk
Category: Health News
Created: 8/18/2022 12:00:00 AM
Last Editorial Review: 8/19/2022 12:00:00 AM

Title: When Hospital Patient & Doctor Speak Same Language, Outcomes Improve
Category: Health News
Created: 7/11/2022 12:00:00 AM
Last Editorial Review: 7/11/2022 12:00:00 AM

Title: Australia's Current Flu Season Is Tough: Will America's Be the Same?
Category: Health News
Created: 8/4/2022 12:00:00 AM
Last Editorial Review: 8/5/2022 12:00:00 AM

Title: Postpartum Depression Can Hit Both Mom & Dad, Sometimes at Same Time
Category: Health News
Created: 6/27/2022 12:00:00 AM
Last Editorial Review: 6/28/2022 12:00:00 AM

The human major histocompatibility complex (MHC) is a ~4 Mb genomic segment on Chromosome 6 that plays a pivotal role in the immune response. Despite its importance in various traits and diseases, its complex nature makes it challenging to accurately characterize on a routine basis. We present a novel approach allowing targeted sequencing and de novo haplotypic assembly of the MHC region in heterozygous samples, using long-read sequencing technologies. Our approach is validated using two reference samples, two family trios, and an African-American sample. We achieved excellent coverage (96.6%–99.9% with at least 30x depth) and high accuracy (99.89%–99.99%) for the different haplotypes. This methodology offers a reliable and cost-effective method for sequencing and fully characterizing the MHC without the need for whole-genome sequencing, facilitating broader studies on this important genomic segment and having significant implications in immunology, genetics, and medicine.

In this study, the nonclinical pharmacokinetics of OLX702A-075-16, an RNA interference therapeutic currently in development, were investigated. OLX702A-075-16 is a novel N-acetylgalactosamine conjugated asymmetric small-interfering RNA (GalNAc-asiRNA) used for the treatment of an undisclosed liver disease. Its unique 16/21-mer asymmetric structure reduces nonspecific off-target effects without compromising efficacy. We investigated the plasma concentration, tissue distribution, metabolism, and renal excretion of OLX702A-075-16 following a subcutaneous administration in mice and rats. For bioanalysis, high-performance liquid chromatography with fluorescence detection was used. The results showed rapid clearance from plasma (0.5 to 1.5 hours of half-life) and predominant distribution to the liver and/or kidney. Less than 1% of the liver concentration of OLX702A-075-16 was detected in the other tissues. Metabolite profiling using liquid chromatography coupled with high-resolution mass spectrometry revealed that the intact duplex OLX702A-075-16 was the major compound in plasma. The GalNAc moiety was predominantly metabolized from the sense strand in the liver, with the unconjugated sense strand of OLX702A-075-16 accounting for more than 95% of the total exposure in the rat liver. Meanwhile, the antisense strand was metabolized by the sequential loss of nucleotides from the 3'-terminus by exonuclease, with the rat liver samples yielding the most diverse truncated forms of metabolites. Urinary excretion over 96 hours was less than 1% of the administered dose in rats. High plasma protein binding of OLX702A-075-16 likely inhibited its clearance through renal filtration.

Two runners saved by the same public defibrillator appeal for all the life-saving devices to be publicly available. Tens of thousands of defibs are unregistered so ‘invisible’ in an emergency.

Sam Howell tells New Scientist why NASA is so keen to visit Jupiter’s fourth-largest moon, Europa, and how the mission could help us figure out the likelihood of life elsewhere in the cosmos

What if tech bros ruled the world, asks Asif Kapadia's 2073. This docudrama is captivating and disturbing, but lacks enough heft to stand out

Large language models can be used to scam humans, but AI is also susceptible to being scammed – and some models are more gullible than others

It’s the second-shortest book to be awarded the prize.

It says these components will enable "the industry's highest DRAM bit density".

Bütün ihtiyaçlara en iyi şekilde karşılık veren Samsun perde modelleri bütçe dostu fiyatlarla sunulmaktadır. Fon perde, tül perde, stor perde, güneşlik ve plise SAMSUN Ucuz Perde Modelleri ve Fiyatları. Siz hemen şimdi maviperde.com'dan güvenle alışveriş yapın, biz SAMSUN'un her yerine ucuz perde modellerini imalattan Samsun Perde Mağazaları ve PERDES Brillant Şubeleri: İlkadım, Atakum, Bafra, Çarşamba, Canik, Vezirköprü, Terme, Tekkeköy, Havza, 19 Mayıs, Alaçam perdeci, Samsun bölgesi zebra perdeci, zebra perdeci, perdeciler Samsun, perdeci adres Samsun, perde servisi. Samsun zebra perde montajı montajcısı. https://asrtekstil.com/

While other bears battled over fish in a prime spot, Otis would sit off to the side and wait for the fish to come to him. But so far this year, he hasn’t been spotted in Katmai National Park and Preserve

Sam Trabucco, the former Alameda Research co-CEO, will forfeit a 53-foot yacht and forgo $70 million worth of claims in a proposed settlement with the FTX bankruptcy estate.

The post Sam Bankman-Fried Henchman to Forfeit $70 Million, Yacht in Proposed Settlement appeared first on Breitbart.

Tentatively called D55, the film is produced by Sushmita Anbuchezian under the Gopuram Films banner

Directors Raj & DK bring texture and technique to this Indian spin-off of ‘Citadel’, with uneven results

The film looks to deliver an exploration of samurai culture in a tumultuous era that aligns with a renewed global interest in samurai narratives, spurred by FX’s ‘Shōgun’

One of the biggest advantages to PC gaming is having access to multiple generations of game releases. We’ve seen entire …

Continue reading "Musou Games on Steam Deck – Samurai Warriors, Dynasty Warriors, Warriors Orochi, Empires, and Much More Tested on Steam Deck OLED"

Hello gentle readers, and welcome to the SwitchArcade Round-Up for August 20th, 2024. In today’s article, I’ve got a couple …

Continue reading "SwitchArcade Round-Up: Reviews Featuring ‘Sam & Max: The Devil’s Playhouse’, Plus the Latest Releases and Sales"

You know the drill by now: cloud money good, consumer PC sales not.

ITV previously seemed very happy to oblige politicians in urgent need of money, rehabilitation or just missing the attention, writes Sean O’Grady. But this year’s roster is different

Samsung has upped the TV stakes with a new range of smart TVs with “QLED” displays.

Gros succès en France, le drame biographique est présenté samedi au Festival Cinemania.

Mar 13, 2024

Social media’s unregulated evolution over the past decade holds a lot of lessons that apply directly to AI companies and technologies.

Samruk Kazyna Corporate Transformation is Set to Generate an Additional $11bn in Revenues to Kazakhstan in the Next Six Years

AARP's Travel Ambassador Samantha Brown Unveils the 2016 Top Travel Trends for Baby Boomers

IBM Watson is bringing cognitive computing to education to bring personalized learning to kids around the world - transforming early childhood education to help kids grow smarter, stronger and kinder.

Years ago, NASA�s Hubble Space Telescope launched with an error in the telescope�s mirror, which blurred its images for its first years in orbit. For NASA�s upcoming James Webb Space Telescope that is traveling much farther out in space, there can�t be a mistake. Abbott scientists created a technology to calibrate the mirrors on NASA�s new James Webb Space Telescope, which is now the same technology used in the iDesign System that allows ophthalmologists to map the human eye with great precision for a highly personalized LASIK treatment.

Assam Bypolls: असम में पांच विधानसभा सीटों के लिए उपचुनाव हो रहे हैं।   9.1 लाख मतदाताओं में से करीब 13% ने पहले दो घंटों में मतदान कर लिया है। चुनाव आयोग के अनुसार, सुबह 9 बजे तक 9,09,057 पात्र मतदाताओं में

The Hon'ble Madras High Court in the case of M/s S.R.S. Construction v. The State Tax Officer (Data Analytics) [Writ Petition (MD) Nos. 16214 & 16276 of 2024 dated July 19, 2024] set aside the orders which have been signed by the same officer in dual capacity, holding that such orders are liable to

Cleo Sol “Fear When You Fly” The majority of people making traditional 20th century-style R&B music today are young enough that, almost unavoidably, their frame of reference for the music has been filtered through five decades of sampling in rap. I feel like this gets filtered back into the traditional music in different ways – […]

Large language models can be used to scam humans, but AI is also susceptible to being scammed – and some models are more gullible than others

Series debuted in October 2023

Archaeologists have uncovered more of the monumental Temple of Poseidon in Greece’s Peloponnese, revealing rare artifacts and unique architectural features that shed light on ancient religious practices .

Continue reading Temple of Poseidon at Samikon is larger than expected at The Wild Hunt.

About 1500 workers in Tamil Nadu state have been striking work for the past 11 days.

The first book set in space to win, Orbital follows astronauts in the International Space Station.

Novel device developed can be clipped onto a smartphone to rapidly test for Zika virus in a single droplet of blood, reveal researchers at the University of Illinois Urbana-Champaign.

Highlights: Samridhi Shukla is a performer and actor Despite her busy schedule, she manages to maintain a health