sex Former Sussex County Doctor Indicted for Insurance Fraud By news.delaware.gov Published On :: Wed, 10 Jul 2019 11:21:40 +0000 Dover, DE – Dr. Jean Vertus Laine, 42, formerly of Peoples Wellness Center, 556 South DuPont Highway, Milford Delaware, was indicted on Monday, July 8th, 2019 by a Sussex County Grand Jury, following an investigation by the DOI Fraud Prevention Unit. The indictment alleges that between August and October of 2017, Doctor Jean Laine fraudulently […] Full Article Insurance Commissioner Consumer Fraud fraud Insurance Commissioner Trinidad Navarro Trinidad Navarro
sex Sussex County Woman Indicted for Insurance Fraud By news.delaware.gov Published On :: Fri, 13 Sep 2019 13:29:23 +0000 Dover, DE—Janet Lane, 59, formerly of Ocean View, Delaware was indicted on Monday September 9th, 2019 by a Sussex County Grand Jury for two counts of insurance fraud and one count of identity theft following an investigation by the Delaware Department of Insurance Fraud Prevention Unit. Ms. Lane had been a passenger in a car […] Full Article Insurance Commissioner Delaware Department of Insurance Department of Insurance Fraud Prevention Unit Insurance Commissioner Trinidad Navarro Trinidad Navarro
sex Sussex Gardeners decorate Lewes, Del.’s Zwaanendael Museum for the holidays By news.delaware.gov Published On :: Wed, 27 Nov 2019 20:43:26 +0000 Theme for the 2019 display is “Here We Go a Caroling.” Full Article Historical and Cultural Affairs News Sussex County activities beaches children events exhibits family free historic sites history holidays museums
sex Sussex County Horse Tests Positive for Eastern Equine Encephalitis By news.delaware.gov Published On :: Thu, 19 Sep 2013 17:14:37 +0000 A horse from Sussex County has tested positive for Eastern Equine Encephalitis, a mosquito-borne disease, the Delaware Department of Agriculture announced today. Full Article Department of Agriculture animal health equine encephalitis horses
sex Sussex Tech’s Mitchell earns DFA forestry scholarship By news.delaware.gov Published On :: Wed, 01 Aug 2018 13:34:12 +0000 Shawn Patrick Mitchell of Greenwood, a recent graduate of Sussex Tech who plans to study wildlife and fisheries at Frostburg State University, received the Delaware Forestry Association's 2018 scholarship at the Delaware State Fair last week. Agriculture Secretary Michael T. Scuse and Governor John C. Carney were there to present the ceremonial check to Mitchell as his parents David and Melissa looked on. Once he earns his bachelor's of science degree, Mitchell hopes to be a game warden or park ranger one day. Full Article Agriculture Department of Agriculture Forest Service Governor John Carney News Sussex County agricultural education Delaware Agriculture Secretary Michael Scuse Delaware Forestry Association Delaware State Fair forestry scholarship
sex DPH TO HOLD MASS CARE EXERCISE AT SUSSEX CENTRAL HIGH SCHOOL JUNE 19-20, 2018 By news.delaware.gov Published On :: Fri, 15 Jun 2018 15:10:13 +0000 The Division of Public Health (DPH) will host a two-day, exercise on Tuesday, June 19, and Wednesday, June 20, at Sussex Central High School, Georgetown. The purpose is to test the division’s ability to operate a shelter for residents who may be displaced or unable to occupy their homes in the event of a disaster. Full Article Division of Public Health News DPH emergency exercise mass care operations shelter
sex Delaware Health Officials Issue Warning for Sussex County after Suspected Overdoses By news.delaware.gov Published On :: Wed, 18 Jul 2018 20:06:00 +0000 NEW CASTLE (July 18, 2018) – With more than half of the deaths from suspected overdoses occurring in Sussex County so far this month, Department of Health and Social Services (DHSS) Secretary Dr. Kara Odom Walker is urging the community to be aware of the uptick and also is warning people in active substance use […] Full Article Delaware Health and Social Services Governor John Carney News Office of the Governor Office of the Lieutenant Governor Sussex County
sex Sussex County Man Tests Positive for West Nile Virus By news.delaware.gov Published On :: Thu, 09 Aug 2018 20:26:23 +0000 The Division of Public Health (DPH) is announcing that a 60-year-old Sussex County man has tested positive for the state’s first human case of West Nile Virus (WNV) in 2018. The man was briefly hospitalized for illness in July and after a preliminary positive test result from the DPH Laboratory in Smyrna, the blood sample was sent to the Centers for Disease Control and Prevention (CDC) for confirmatory testing. WNV, a mosquito-borne illness, can become serious, and DPH reminds people to take precautions to avoid mosquito bites. Full Article Delaware Health and Social Services Division of Public Health News DNREC Mosquito Control Section mosquito season mosquito-borne diseases mosquitoes public health West Nile Virus
sex Seek Treatment, Access to Naloxone: Three Suspected Heroin Overdose Deaths in Sussex Co. Involving Same Packet Stamp By news.delaware.gov Published On :: Wed, 13 Mar 2019 19:24:56 +0000 NEW CASTLE (March 13, 2019) – Health and public safety officials are urging people in active use of heroin or other opioids and their families to seek immediate treatment and acquire the overdose-reversing medication naloxone on hand in the wake of three suspected heroin overdose deaths in five days in Sussex County involving the same […] Full Article Delaware Health and Social Services Division of Public Health News Office of the Governor fatal overdose Fentanyl Heroin Naloxone overdose response
sex Patients of Sussex County Doctor Whose Medical License, Controlled Substance Registration Revoked Getting Resources By news.delaware.gov Published On :: Thu, 09 May 2019 22:10:00 +0000 DOVER (May 9, 2019) – On May 8, 2019, the medical license and controlled substance registrations of Nihar B. Gala, MD, were permanently revoked by the Delaware Board of Medical Licensure and Discipline. The revocation was a result of allegations of unprofessional conduct related to the prescription of opioids to a patient at high risk […] Full Article Delaware Health and Social Services Department of State Division of Public Health News Sussex County controlled substance registration Dr. Nihar B. Gala DSAMH HelpIsHereDE.com medical license Mobile Crisis prescriber revoked
sex Sussex County Bridge Clinic to Help Individuals, Families Impacted by Mental Illness, Opioid Use Disorder By news.delaware.gov Published On :: Thu, 11 Jul 2019 17:07:08 +0000 NEW CASTLE (July 11, 2019) – As a new support for individuals and families impacted by the effects of mental health and substance use issues, the Division of Substance Abuse and Mental Health (DSAMH) officially will open the Sussex County Bridge Clinic on July 15 at the Promise Access Center in Georgetown, providing screening and […] Full Article Delaware Health and Social Services News Division of Substance Abuse and Mental Health health and safety mental health opioid epidemic opioids
sex Flu is Now Confirmed Statewide; DPH Announces First Flu Cases in Kent and Sussex Counties for the 2019-2020 Season By news.delaware.gov Published On :: Mon, 14 Oct 2019 16:04:40 +0000 The Delaware Division of Public Health (DPH) is reporting the state’s first laboratory-confirmed cases of influenza in Kent and Sussex counties, for the 2019-2020 flu season. The Kent County case involves a 26-year-old female, while the Sussex County case involves a 7-year-old male. This brings the total number of flu cases this season to three. The first confirmed flu case for New Castle County was announced last week. Full Article Delaware Health and Social Services Division of Public Health News 2019-2020 flu season flu flu shot flu vaccine influenza public health
sex TRAFFIC ALERT - Reconstruction of Island and Traffic Pattern Change at Route 1 NB/SB-Sussex County By www.deldot.gov Published On :: Fri, 01 May 2020 14:48:15 GMT Milton -- Locations: Route 1 Northbound/Southbound between Primehook Road and Deep Branch Road, Milton. Times and Dates: 6:30 a.m. until 6:30 p.m., Monday through Sunday, pending weather. April 6, 2020 through May 27, 2020 Traffic Information: The Delaware Department of Transportation (DelDOT) announces to motorists that work is scheduled to begin at the intersection at Route 5 and Route 1 for the reconstruction of the intersection. [More] Full Article Traffic
sex TRAFFIC ALERT - Replacement of Crossroad Pipes in Sussex County By www.deldot.gov Published On :: Thu, 07 May 2020 11:30:00 GMT Selbyville -- Traffic Information: DelDOT announces to motorists that the following roads will be closed for the removal and replacement of a crossroad pipe for drainage improvements. Times and Dates: 7:00 a.m. on May 12, 2020 until 11:00 p.m. on May 18, 2020, pending weather. Location: Johnson Road between Dickerson Road and Johnson Store Road, Selbyville. [More] Full Article Traffic
sex Governor Carney Partners with Health Providers and Sussex Employers on Community Testing Sites, Outreach, Education By news.delaware.gov Published On :: Wed, 22 Apr 2020 17:33:15 +0000 WILMINGTON, Del. – Governor John Carney on Wednesday announced a partnership with the Delaware Division of Public Health (DPH), the Delaware Department of Health and Social Services (DHSS), the Delaware Emergency Management Agency, the Delaware Department of Agriculture, Westside Family Healthcare, local hospital systems, poultry industry employers, Federally Qualified Health Centers, and trusted community partners […] Full Article Governor John Carney Office of the Governor agriculture Coronavirus sussex testing
sex Governor Carney Declares COVID-19 Hot Spot in Sussex County, Announces Expansion of Community Testing Sites By news.delaware.gov Published On :: Tue, 28 Apr 2020 18:28:45 +0000 Governor John Carney on Tuesday declared Sussex County a hot spot for COVID-19 in Delaware and announced the initial schedule for the State of Delaware’s Coordination and Care community testing sites. Testing and outreach will occur in several Sussex communities that are at the center of Delaware's COVID-19 epidemic. Governor Carney first announced the community testing and outreach partnership among the state, hospital systems, and others last week, with an initial focus on Sussex County. Full Article Governor John Carney Office of the Governor Coronavirus
sex Sussex County: Coronavirus testing sites announced April 29-May 4, 2020 By news.delaware.gov Published On :: Wed, 29 Apr 2020 15:44:04 +0000 Looking for coronavirus testing locations in Sussex County? See below for dates, times, and locations starting today, April 29 thru May 4, 2020. Community Testing Site hosted by Beebe Healthcare in the parking lot between JD Shuckers and the Veteran’s Administration off of Rt. 404 in Georgetown: Wednesday, April 29 from 10 a.m. – 4 p.m. Community Testing Site […] Full Article Delaware Health and Social Services Division of Public Health Coronavirus coronavirus testing covid 19 testing covid19 Sussex County
sex Recovery Town Hall – May 6, 7:30pm – Sussex County focus By news.delaware.gov Published On :: Wed, 06 May 2020 14:45:15 +0000 May 6 at 7:30 p.m. – Lieutenant Governor Bethany Hall-Long will host a virtual town hall meetings with stakeholder groups and members of the public to collect public feedback that will inform Delaware’s recovery effort. Learn more and submit feedback online: de.gov/economy Upcoming Recovery Town Hall with Lieutenant Governor Hall-Long: Recovery Town Hall – […] Full Article Featured Video Lt. Governor Bethany Hall-Long Office of the Governor Office of the Lieutenant Governor
sex OPEN-END CONSTRUCTION SERVICES, KENT & SUSSEX COUNTY By www.deldot.gov Published On :: Fri, 13 Dec 2019 05:00:00 GMT OPEN-END CONSTRUCTION SERVICES, KENT & SUSSEX COUNTY Full Article
sex Search Engine For Japanese Sex Hotels Announces Security Breach By packetstormsecurity.com Published On :: Mon, 06 Jan 2020 16:01:25 GMT Full Article headline privacy data loss japan
sex Best sex toys for women: Take pleasure into your own hands By feeds.mashable.com Published On :: Fri, 17 May 2019 16:53:13 +0000 BEST DEALS ON SEX TOYS: Ella Paradis — Get up to 80% off Lovehoney Jessica Rabbit 10 Function Silver Rabbit Vibrator — $39.99 Lelo Sona Cruise — $99 (save $40) If Instagram is to be believed, then self care for women basically amounts to face masks and daily affirmation apps. Hot take: Sex toys are the ultimate self-care purchase. Orgasms release oxytocin, the anti-stress hormone that gets you warm and fuzzy when cuddling, while dopamine, a neurotransmitter that regulates sleep, also makes an appearance. It stands to reason, then, that "I need to get laid" is a thing that actually makes sense to say when you're having a rough week. Read more...More about Culture, Sex, Sex Toys, Vibrators, and Masturbation IMAGE: Unbound Babes BEST FOR BEGINNERS Squish by Unbound This adorable, button-free toy has risen to stardom due to simplicity: Harder squeezes equal stronger vibrations. Stimulation: Clitoral Vibration modes: 5 Waterproof: Yes USB rechargeable: Yes $99 from Unbound Babes IMAGE: Adam & Eve BEST RABBIT VIBRATOR Fifty Shades of Grey G-Spot Vibrator Rabbit vibrators are the go-to for simultaneous internal and G-spot stimulation and this one packs 36 total vibration modes. Stimulation: G-spot, clitoral Vibration modes: 36 Waterproof: Yes USB rechargeable: Yes $99.99 from Adam & Eve IMAGE: Love Crave BEST CLASSIC VIBRATOR Crave Vesper Vibrator Necklace You can take that tingly feeling wherever you go with this quiet vibrator that's also a statement necklace. Stimulation: Clitoral Vibration modes: 4 Waterproof: Yes USB rechargeable: Yes $69 from Love Crave IMAGE: Babeland BEST COCK RING FOR FEMALE PLEASURE Je Joue Mio One of the best cock rings to help you achieve dual pleasure, the Je Joue Mio offers a comfy fit and impressive rumbles. Stimulation: Clitoral Vibration modes: 12 Waterproof: Yes USB rechargeable: Yes $109 from Babeland IMAGE: Ella Paradis BEST ORAL SEX SIMULATOR Womanizer Premium Clitoral Massager Get the sensation of oral sex with this erotic combo of air, suction, and pattern randomization. Stimulation: Clitoral Vibration modes: 12 Waterproof: Yes USB rechargeable: Yes $239 from Ella Paradis IMAGE: Lelo BEST FOR THE SHOWER Lelo Sona Cruise This ergonomic toy sucks (in a good way) and uses sonic waves to hit interior parts of the clitoris. Stimulation: Clitoral Vibration modes: 8 Waterproof: Yes USB-rechargeable: Yes $99 from Lelo IMAGE: Lovehoney BEST BUTT PLUG Butt Tingler by Lovehoney Though not the prettiest one out there, it exceeds expectations as a beginner-friendly option. Stimulation: Anal Vibration modes: 10 Waterproof: Yes USB rechargeable: No $26.99 from Lovehoney IMAGE: Lelo BEST WAND Lelo Smart Wand Medium A curved handle and naturally-increasing intensity prove that wands made for masturbation are better than your generic "personal massager." Stimulation: Clitoral Vibration modes: 8 Waterproof: Yes USB rechargeable: Yes $159 from Lelo IMAGE: Ella Paradis BEST FOR USE WITH A PARTNER We-Vibe Sync Couples can use the app with this remote-controlled vibrator to up the intimacy, even if you're states apart. Stimulation: G-spot, clitoral Vibration modes: 12 Waterproof: Yes USB rechargeable: Yes $229 from Ella Paradis IMAGE: Geeky Sex Toys BEST FOR HBO AND CHILL Game of Moans Longclaw Dildo The eighth season may not be moan-worthy, but this girthy dildo version of Jon Snow's sword is. Stimulation: G-spot, anal Vibration modes: None Waterproof: Yes USB rechargeable: N/A $130 from Geeky Sex Toys Full Article Culture Sex Sex Toys Vibrators Masturbation
sex Case comment: Amey Highways Limited v West Sussex County Council By www.eversheds.com Published On :: 2019-07-01 The recent High Court decision in Amey Highways Limited v West Sussex County Council has clarified that abandoning a procurement will not automatically extinguish pre-existing causes of action. Breaches of the procurement regulations which res... Full Article
sex Alive Amidst the Mayhem of COVID-19 – A Sex Worker’s Story By www.ipsnews.net Published On :: Thu, 09 Apr 2020 09:21:31 +0000 For a Bangladeshi woman, who has worked as a sex worker since childhood, her future post-COVID-19 looks hopeless. Shilpy, who works at Daulatdia, the largest brothel in the country, told IPS how she now also fears for the future of her two daughters. “When I was born, the woman my mother worked for gave everyone […] The post Alive Amidst the Mayhem of COVID-19 – A Sex Worker’s Story appeared first on Inter Press Service. Full Article Asia-Pacific Economy & Trade Featured Financial Crisis Gender Headlines Health Human Rights Labour TerraViva United Nations
sex Ensuring Russia’s Sex Workers’ Rights Essential for Wider Gender Equality By www.ipsnews.net Published On :: Mon, 27 Apr 2020 09:51:32 +0000 Ensuring sex workers’ rights was essential, not just for the workers themselves, but for any country’s wider society, including public health The post Ensuring Russia’s Sex Workers’ Rights Essential for Wider Gender Equality appeared first on Inter Press Service. Full Article Crime & Justice Editors' Choice Europe Featured Gender Headlines Health Human Rights LGBTQ Regional Categories TerraViva United Nations Global Network of Sex Work Projects Russia Russian Forum of Sex Workers sex workers Sex Workers’ Rights Advocacy Network (SWAN) Women Deliver
sex Streetwalkers to sweet talkers: Chile's sex workers shift online amid virus lockdown By feeds.reuters.com Published On :: Wed, 06 May 2020 19:50:04 -0400 When the nightclub in which she touted for business in southern Chile was shut down by the authorities as the new coronavirus spread, sex worker Camila Hormazabal was left without access to her sole... Full Article lifestyleMolt
sex Sex Lives Often an Overlooked Casualty of Traumatic Brain Injury By www.medicinenet.com Published On :: Sat, 9 May 2020 00:00:00 PDT Title: Sex Lives Often an Overlooked Casualty of Traumatic Brain InjuryCategory: Health NewsCreated: 4/29/2013 2:35:00 PMLast Editorial Review: 4/30/2013 12:00:00 AM Full Article
sex Sex Still Matters to Many Seniors, Survey Finds By www.medicinenet.com Published On :: Sat, 9 May 2020 00:00:00 PDT Title: Sex Still Matters to Many Seniors, Survey FindsCategory: Health NewsCreated: 5/3/2018 12:00:00 AMLast Editorial Review: 5/4/2018 12:00:00 AM Full Article
sex Less Sex Could Mean Earlier Menopause By www.medicinenet.com Published On :: Thu, 16 Jan 2020 00:00:00 PDT Title: Less Sex Could Mean Earlier MenopauseCategory: Health NewsCreated: 1/15/2020 12:00:00 AMLast Editorial Review: 1/16/2020 12:00:00 AM Full Article
sex Pooling Pharyngeal, Anorectal, and Urogenital Samples for Screening Asymptomatic Men Who Have Sex with Men for Chlamydia trachomatis and Neisseria gonorrhoeae [Bacteriology] By jcm.asm.org Published On :: 2020-04-23T08:00:29-07:00 Screening for Chlamydia trachomatis and Neisseria gonorrhoeae at the pharyngeal, urogenital, and anorectal sites is recommended for men who have sex with men (MSM). Combining the three individual-site samples into a single pooled sample could result in significant cost savings, provided there is no significant sensitivity reduction. The aim of this study was to examine the sensitivity of pooled samples for detecting chlamydia and gonorrhea in asymptomatic MSM using a nucleic acid amplification test. Asymptomatic MSM who tested positive for chlamydia or gonorrhoea were invited to participate. Paired samples were obtained from participants prior to administration of treatment. To form the pooled sample, the anorectal swab was agitated in the urine specimen transport tube and then discarded. The pharyngeal swab and 2 ml of urine sample were then added to the tube. The difference in sensitivity between testing of pooled samples and individual-site testing was calculated against an expanded gold standard, where an individual is considered positive if either pooled-sample or individual-site testing returns a positive result. All samples were tested using the Aptima Combo 2 assay. A total of 162 MSM were enrolled in the study. Sensitivities of pooled-sample testing were 86% (94/109; 95% confidence interval [CI], 79 to 92%]) for chlamydia and 91% (73/80; 95% CI, 83 to 96%) for gonorrhea. The sensitivity reduction was significant for chlamydia (P = 0.02) but not for gonorrhea (P = 0.34). Pooling caused 22 infections (15 chlamydia and 7 gonorrhoea) to be missed, and the majority were single-site infections (19/22). Pooling urogenital and extragenital samples from asymptomatic MSM reduced the sensitivity of detection by approximately 10% for chlamydia but not for gonorrhea. Full Article
sex Unmet Need for Family Planning and Experience of Unintended Pregnancy Among Female Sex Workers in Urban Cameroon: Results From a National Cross-Sectional Study By ghspjournal.org Published On :: 2020-03-31T15:28:55-07:00 ABSTRACTBackground:Female sex workers (FSWs) in Cameroon commonly have unmet need for contraception posing a high risk of unintended pregnancy. Unintended pregnancy leads to a range of outcomes, and due to legal restrictions, FSWs often seek unsafe abortions. Aside from the high burden of HIV, little is known about the broader sexual and reproductive health of FSWs in Cameroon.Methods:From December 2015 to October 2016, we recruited FSWs aged ≥18 years through respondent-driven sampling across 5 Cameroonian cities. Cross-sectional data were collected through a behavioral questionnaire. Modified-robust Poisson regression was used to approximate adjusted prevalence ratios (aPR) for TOP and current use of effective nonbarrier contraception.Results:Among 2,255 FSWs (median age 28 years), 57.6% reported history of unintended pregnancy and 40.0% reported prior TOP. In multivariable analysis, TOP history was associated with current nonbarrier contraceptive use (aPR=1.23, 95% confidence interval [CI]=1.07, 1.42); ever using emergency contraception (aPR=1.34, 95% CI=1.17, 1.55); >60 clients in the past month (aPR=1.29, 95% CI= 1.07, 1.54) compared to ≤30; inconsistent condom use with clients (aPR=1.17, 95% CI=1.00, 1.37); ever experiencing physical violence (aPR=1.24, 95% CI=1.09, 1.42); and older age. Most (76.5%) women used male condoms for contraception, but only 33.2% reported consistent condom use with all partners. Overall, 26.4% of women reported currently using a nonbarrier contraceptive method, and 6.2% reported using a long-acting method. Previous TOP (aPR=1.41, 95%CI=1.16, 1.72) and ever using emergency contraception (aPR=2.70, 95% CI=2.23, 3.26) were associated with higher nonbarrier contraceptive use. Recent receipt of HIV information (aPR=0.72, 95% CI=0.59, 0.89) and membership in an FSW community-based organization (aPR=0.73, 95% CI=0.57, 0.92) were associated with lower use nonbarrier contraceptive use.Conclusions:Experience of unintended pregnancies and TOP is common among FSWs in Cameroon. Given the low use of nonbarrier contraceptive methods and inconsistent condom use, FSWs are at risk of repeat unintended pregnancies. Improved integration of client-centered, voluntary family planning within community-led HIV services may better support the sexual and reproductive health and human rights of FSWs consistent with the United Nations Declaration of Human Rights. Full Article
sex Sex Disparities in Cardiovascular Outcome Trials of Populations With Diabetes: A Systematic Review and Meta-analysis By care.diabetesjournals.org Published On :: 2020-04-20T12:00:33-07:00 BACKGROUND Sex differences have been described in diabetes cardiovascular outcome trials (CVOTs). PURPOSE We systematically reviewed for baseline sex differences in cardiovascular (CV) risk factors and CV protection therapy in diabetes CVOTs. DATA SOURCES Randomized placebo-controlled trials examining the effect of diabetes medications on major adverse cardiovascular events in people ≥18 years of age with type 2 diabetes. STUDY SELECTION Included trials reported baseline sex-specific CV risks and use of CV protection therapy. DATA EXTRACTION Two reviewers independently abstracted study data. DATA SYNTHESIS We included five CVOTs with 46,606 participants. We summarized sex-specific data using mean differences (MDs) and relative risks (RRs) and pooled estimates using random effects meta-analysis. There were fewer women than men in included trials (28.5–35.8% women). Women more often had stroke (RR 1.28; 95% CI 1.09, 1.50), heart failure (RR 1.30; 95% CI 1.21,1.40), and chronic kidney disease (RR 1.33; 95% CI 1.17; 1.51). They less often used statins (RR 0.90; 95% CI 0.86, 0.93), aspirin (RR 0.82; 95% CI 0.71, 0.95), and β-blockers (RR 0.93; 95% CI 0.88, 0.97) and had a higher systolic blood pressure (MD 1.66 mmHg; 95% CI 0.90, 2.41), LDL cholesterol (MD 0.34 mmol/L; 95% CI 0.29, 0.39), and hemoglobin A1c (MD 0.11%; 95% CI 0.09, 0.14 [1.2 mmol/mol; 1.0, 1.5]) than men. LIMITATIONS We could not carry out subgroup analyses due to the small number of studies. Our study is not generalizable to low CV risk groups nor to patients in routine care. CONCLUSIONS There were baseline sex disparities in diabetes CVOTs. We suggest efforts to recruit women into trials and promote CV management across the sexes. Full Article
sex Starvation causes female-to-male sex reversal through lipid metabolism in the teleost fish, medaka (Olyzias latipes) [RESEARCH ARTICLE] By bio.biologists.org Published On :: 2020-04-07T00:30:09-07:00 Yuta Sakae, Akira Oikawa, Yuki Sugiura, Masatoshi Mita, Shuhei Nakamura, Toshiya Nishimura, Makoto Suematsu, and Minoru Tanaka The teleost fish, medaka (Oryzias latipes), employs the XX/XY genetic sex determination system. We show here that the phenotypic sex of medaka is affected by changes in lipid metabolism. Medaka larvae subjected to 5 days of starvation underwent female-to-male sex reversal. Metabolomic and RT-qPCR analyses indicated that pantothenate metabolism was suppressed by starvation. Consistently, inhibiting the pantothenate metabolic pathway caused sex reversal. The final metabolite in this pathway is coenzyme A, an essential factor for lipogenesis. Inhibiting fatty acid synthesis, the first step of lipogenesis, also caused sex reversal. The expression of dmrt1, a critical gene for male development, was suppressed by starvation, and a dmrt1 (13) mutant did not show sex reversal under starvation. Collectively, these results indicate that fatty acid synthesis is involved in female-to-male sex reversal through ectopic expression of male gene dmrt1 under starvation. Full Article
sex Prediagnostic Circulating Levels of Sex Steroid Hormones and SHBG in Relation to Risk of Ductal Carcinoma In Situ of the Breast among UK Women By cebp.aacrjournals.org Published On :: 2020-05-01T00:05:36-07:00 Background: Sex steroid hormones and sex hormone–binding globulin (SHBG) have been implicated in the etiology of invasive breast cancer, but their associations with risk of the precursor lesion, ductal carcinoma in situ (DCIS) of the breast, remain unclear. Methods: We used Cox proportional hazards regression models to estimate the associations of serum levels of estradiol (premenopausal women only), testosterone, and/or SHBG with DCIS risk among 182,935 women. After a median follow-up of 7.1 years, 186 and 531 DCIS cases were ascertained in premenopausal and postmenopausal women, respectively. Results: Total and free estradiol were positively associated with risk of DCIS among premenopausal women. The HRs for the highest versus the lowest tertiles were 1.54 (1.06–2.23) and 1.72 [95% confidence interval (CI), 1.15–2.57], respectively. Among postmenopausal women, elevated levels of free testosterone (FT), and to a lesser extent, total testosterone, were positively associated with DCIS risk. The HRs for the highest versus the lowest quartiles were 1.42 (95% CI, 1.09–1.85) and 1.16 (95% CI, 0.91–1.48), respectively. Serum SHBG levels were inversely associated with risk of DCIS among postmenopausal women (HRq4 vs. q1: 0.75; 95% CI, 0.56–0.99). Conclusions: This study suggests that elevated levels of estradiol are associated with increased risk of DCIS among premenopausal women, and that among postmenopausal women, elevated levels of testosterone, and particularly those of FT, are associated with increased DCIS risk, while elevated levels of SHBG are associated with reduced risk. Impact: These findings may be helpful in developing prevention strategies aimed at reducing breast cancer risk among premenopausal and postmenopausal women. Full Article
sex Prepare for Sex and Dating to Get Even More Complicated Once the Lockdown Lifts By feedproxy.google.com Published On :: Sat, 09 May 2020 09:02:46 GMT Mario Tama/GettyFor the past two months, Katie Holliday has been cooped up alone in her Brooklyn apartment thinking longingly about an unlikely erogenous zone: the lower half of a stranger’s face. “I remember joking to my friend before all of this started, ‘Imagine if someone’s face becomes their most coveted body part?’” Holliday, who is 31, told The Daily Beast. “‘When someone removes their mask, is it a sign of trust? Is it like letting someone see you naked?’ I was kidding back then, but now it’s reality.”Holliday doesn’t know exactly when it will be safe to start seeing people like she did before the pandemic began, but she’ll return to a singles scene unlike any other in history. “I’m picturing walking into a bar where everyone’s wearing masks,” she said. “I’ll meet someone whose face is covered. Are they cute or not? I don’t know!” Read more at The Daily Beast. Full Article Arts and Culture
sex Australian Scientists Discover 'Virgin' Bees That Don't Have Sex And Only Give Birth To Females By feeds.gizmodo.com.au Published On :: Fri, 08 May 2020 13:20:47 +1000 Researchers at a Sydney university have discovered how some female bees have managed to reproduce despite never doing the deed with another. More » Full Article
sex New Zealand sees sex toy boom as major manufacturer declared 'essential service' during coronavirus lockdown By www.standard.co.uk Published On :: 2020-04-09T07:14:00Z Covid-19: The symptoms Read our live blogs for updates here Full Article
sex Celebrities join Earl of Wessex to send 'virtual congratulations' to Duke of Edinburgh award winners By www.standard.co.uk Published On :: 2020-04-15T09:28:00Z Follow our live coronavirus updates HERE Coronavirus: The symptoms Full Article
sex Two arrests in sex trafficking probe linked to north London brothels By www.standard.co.uk Published On :: 2020-04-16T08:32:38Z Detectives investigating a gang responsible for trafficking young women from Brazil to work in brothels in north London have made two arrests. Full Article
sex Food For London Now: Duchess of Sussex backs Evening Standard appeal to help feed the hungry By www.standard.co.uk Published On :: 2020-04-17T09:29:00Z Meghan says spirit of Grenfell lives on in video call to women she helped at kitchen You can donate at virginmoneygiving.com/fund/FoodforLondonNOW Full Article
sex Man charged with manslaughter in Essex lorry deaths probe By www.standard.co.uk Published On :: 2020-04-20T20:46:20Z A man has been charged with manslaughter in connection with the deaths of 39 migrants found in a refrigerated lorry container in Essex. Full Article
sex Sex attacker jailed after drugging victim he met outside London pub By www.standard.co.uk Published On :: 2020-04-23T20:11:42Z An "evil" sex attacker who drugged and assaulted his victim after meeting him outside a London pub has been jailed. Full Article
sex More than 1,000 possible child sex offences flagged to police during coronavirus lockdown By www.standard.co.uk Published On :: 2020-04-25T16:57:00Z Police have been alerted to more than 1,000 potential child sexual abuse cases during the coronavirus pandemic, the Home Secretary has said. Full Article
sex Karissa Sanbonmatsu: What Can Epigenetics Tell Us About Sex And Gender? By www.npr.org Published On :: Fri, 08 May 2020 09:15:00 -0400 We're used to thinking of DNA as a rigid blueprint. Karissa Sanbonmatsu researches how our environment affects the way DNA expresses itself—especially when it comes to sex and gender. Full Article
sex Kevin Spacey breaks silence over sex assault claims to compare industry shunning to coronavirus job losses By uk.movies.yahoo.com Published On :: Wed, 06 May 2020 16:10:13 GMT Actor Kevin Spacey has broken his silence over sex assault allegations, comparing being shunned by the film industry to those who are out of work as a result of the coronavirus crisis. The 60-year-old American Beauty star has not appeared in a professional movie or series since accusations of abuse were made by several men. "I don't think it will come as a surprise for anyone to say that my world completely changed in the fall of 2017,” he said in comments made during an interview for the German business conference Bits & Pretzels podcast. “My job, many of my relationships, my standing in my own industry were all gone in just a matter of hours.” The former House of Cards lead, who was dropped by the show after allegations surfaced, has largely kept a low profile since the allegations were made. He was also removed from the film All the Money in the World, which had to be reshot with actor Christopher Plummer. Spacey has always denied the claims, several of which date back several decades. “While we may have found ourselves in similar situations, albeit for very different reasons and circumstances, I still believe that some of the emotional struggles are very much the same," he said. “And so I do have empathy for what it feels like to suddenly be told that you can't go back to work or that you might lose your job and that it's a situation that you have absolutely no control over.” At the end of the podcast interview, Spacey added: “I was so busy defining myself by what I did or what I was trying to do, that when it all stopped I had no idea what to do next. All I knew how to do was act, I was born to do it. “I don’t want to sugarcoat this devastating time that we’re in, I am hoping that I can encourage you to see an opportunity in all of this and turn this into a positive.” Full Article
sex Netflix's Too Hot to Handle proves the best sex you ever have is the sort you never have By www.independent.co.uk Published On :: 2020-04-20T10:48:00Z They might be so desperate for sex they're willing to pay £20,000 for it, but when the contestants of Too Hot To Handle return to normal life, they may well wonder what they were so looking forward to, writes Annie Lord Full Article
sex Alexis Martin: Governor commutes sentence of sex trafficking survivor supported by Kim Kardashian West By www.independent.co.uk Published On :: 2020-04-21T14:52:40Z Alexis Martin was serving 21 years to life behind bars Full Article
sex From Will & Grace to Sex and the City, why do so many TV reboots lead to our favourite ensemble casts hating each other? By www.independent.co.uk Published On :: 2020-04-22T15:48:00Z As the revival of 'Will & Grace' comes to a close amid allegations of cast feuds and bullying, Adam White asks why so many of our favourite shows seem to implode when they're brought back to life Full Article
sex Clumsy sex and longing stares: How Normal People captures the angst of young romance By www.independent.co.uk Published On :: 2020-04-23T18:58:00Z While plenty of young drama is played for shock or laughs, the anticipated BBC3 adaptation of Sally Rooney's best-selling book lingers on what goes unsaid between its adolescent lovebirds. And there is lots of humping, says arts columnist Fiona Sturges Full Article
sex Normal People: Viewers hail 'abnormally brilliant' BBC drama and praise consensual sex scenes By www.independent.co.uk Published On :: 2020-04-27T08:07:39Z Adaptation of Sally Rooney's love story stars Paul Mescal and Daisy Edgar-Jones Full Article
sex Normal People sparks huge debate on Irish radio over 'immoral' sex scenes: 'It's fornication' By www.independent.co.uk Published On :: 2020-05-01T14:13:52Z BBC series has been widely praised for its depiction of consensual sex between main characters Marianne and Connell Full Article