naloxone

HHS calls for ‘safety stations’ with naloxone in federal buildings

Washington — Federal facilities should convert their current AED stations into “safety stations” that include naloxone – a medication that rapidly reverses the effects of an opioid overdose, the Department of Health and Human Services says.




naloxone

Federal worker advisory committee will discuss naloxone at April meeting

Washington — OSHA’s Federal Advisory Council on Occupational Safety and Health has scheduled a virtual meeting for April 18.




naloxone

Is naloxone in your first aid kit?

Be ready to respond to an opioid overdose at work. “It really is something that’s very simple to administer,” an NSC expert says.




naloxone

New California law requires naloxone in workplace first aid kits

Sacramento, CA — Naloxone hydrochloride or another Food and Drug Administration-approved opioid-reversal medication must be included in all workplace first aid kits in California no later than Dec. 1, 2028.




naloxone

Human Medicines (Amendments Relating to Naloxone and Transfers of Functions) Regulations 2024: Department of Health

Room 29, Parliament Buildings



  • Committee for Health

naloxone

DHSS’ Division of Substance Abuse and Mental Health to Host Free Monthly Naloxone Training Sessions Statewide

NEW CASTLE (March 3, 2022) – The Delaware Department of Health and Social Services’ Division of Substance Abuse and Mental Health (DSAMH) is hosting free monthly Naloxone Access Training for all members of the community. All trainings can be found here: http://delaware-dsamh.eventbrite.com Naloxone, known commonly by the brand-name Narcan, is a medication that is effective […]




naloxone

naloxone

Title: naloxone
Category: Medications
Created: 8/22/2022 12:00:00 AM
Last Editorial Review: 8/22/2022 12:00:00 AM




naloxone

Gabapentinoids Increase the Potency of Fentanyl and Heroin and Decrease the Potency of Naloxone to Antagonize Fentanyl and Heroin in Rats Discriminating Fentanyl [Behavioral Pharmacology]

Despite a significant decrease in the number of prescriptions for opioids, the opioid crisis continues, fueled in large part by the availability of the phenylpiperidine mu opioid receptor (MOR) agonist fentanyl. In contrast, the number of prescriptions for and the off-label use of gabapentinoids (gabapentin and pregabalin) has increased dramatically, with gabapentinoids commonly detected in opioid overdose victims. Although gabapentinoids can decrease the potency of the opioid receptor antagonist naloxone to reverse heroin-induced hypoventilation in male rats, the specificity and nature of interaction between gabapentinoids and MOR agonists and any potential sex difference in those interactions are not well characterized. Gabapentinoids were studied in female and male rats discriminating fentanyl (0.0032 mg/kg, i.p.) or cocaine (3.2 mg/kg, i.p.). Alone, neither gabapentin nor pregabalin significantly increased fentanyl- or cocaine-appropriate responding. In rats discriminating fentanyl, each gabapentinoid dose-dependently shifted the fentanyl and heroin discrimination dose-effect functions to the left, whereas naloxone dose-dependently shifted the fentanyl and heroin discrimination dose-effect functions to the right. Each gabapentinoid (100 mg/kg) significantly decreased the potency of naloxone to antagonize the discriminative stimulus effect of fentanyl or heroin. In contrast, each gabapentinoid dose-dependently shifted the cocaine and d-methamphetamine discrimination dose-effect functions to the right. There were no significant sex differences in this study. These results suggest that gabapentinoids impact the misuse of opioids, the co-use of opioids and stimulant drugs, and the increasing number of overdose deaths in individuals using opioids, stimulant drugs, and gabapentinoids in mixtures.

SIGNIFICANCE STATEMENT

The number of prescriptions for and the off-label use of gabapentinoids (gabapentin and pregabalin) has increased dramatically, with gabapentinoids commonly detected in opioid overdose victims. This study reports that in rats gabapentinoids increase the potency of fentanyl and heroin to produce discriminative stimulus effects while decreasing the potency of naloxone to antagonize those effects of fentanyl and heroin. These results can help guide policies for regulating gabapentinoids and treating opioid misuse and overdose.




naloxone

Naloxone: A Lifesaver for Cardiac Arrest Patients?

medlinkNaloxone/medlink, a life-saving medication, is commonly administered by first responders to individuals who have overdosed on opioids and still have a pulse.




naloxone

Naloxone Drug Cost may Keep may Uninsured from Using Life-saving Treatment

The cost of purchasing the opioid antidote naloxone is out of reach for many uninsured Americans. This may keep the treatment from saving more people




naloxone

Take home naloxone pilot resource order form




naloxone

DPH Announces Sustained Funding for Overdose-Reversing Medication Naloxone

Increasing access to the overdose-reversing medication naloxone has been a key priority for the Delaware Department of Health and Social Services (DHSS) as state and local partners work together to develop solutions to address the opioid epidemic. In support of that, the Department’s Division of Public Health (DPH) is announcing sustained funding for naloxone for first responder agencies statewide.




naloxone

DPH to distribute overdose reversing medication naloxone March 2, 2019 at AtTack Addiction 5K

NEW CASTLE (Feb. 13, 2019) – In an effort to reduce the number of individuals overdosing, and dying from drug overdoses in Delaware, the Division of Public Health (DPH) is announcing the Community Naloxone Distribution Initiative. DPH will distribute free naloxone kits to members of the general public, at events in each county in March. […]




naloxone

DPH to Distribute Overdose Reversing Medication Naloxone March 9, 2019 in Georgetown

GEORGETOWN (March 1, 2019) – In an effort to reduce the number of individuals dying from drug overdoses in Delaware, the Division of Public Health (DPH) will hold Community Naloxone Distribution events in each county throughout the month of March. DPH will distribute free naloxone kits to members of the general public from 10 a.m. […]




naloxone

Seek Treatment, Access to Naloxone: Three Suspected Heroin Overdose Deaths in Sussex Co. Involving Same Packet Stamp

NEW CASTLE (March 13, 2019) – Health and public safety officials are urging people in active use of heroin or other opioids and their families to seek immediate treatment and acquire the overdose-reversing medication naloxone on hand in the wake of three suspected heroin overdose deaths in five days in Sussex County involving the same […]




naloxone

DPH to Distribute Overdose Reversing Medication Naloxone March 20, 2019 in Dover

The Division of Public Health will distribute free naloxone kits to members of the general public from 5:30 p.m. to 8:30 p.m., on Wednesday, March 20, 2019, at Delaware Technical Community College, Terry Campus, 100 Campus Drive, Dover, DE 19904. The distribution event will be held in the Corporate Training Center, Rooms 408 and 412. Individuals are encouraged to stop by at any time during the event. Training takes approximately 15 minutes. 




naloxone

DPH Announces Two Naloxone Training, Distribution Events in New Castle County

NEW CASTLE (March 28, 2019) – As part of its Community Naloxone Distribution initiative, the Division of Public Health (DPH) will hold two additional community naloxone distribution events in New Castle County next week. This initiative is part of a multi-pronged approach to address the opioid crisis and reduce the number of individuals dying from […]




naloxone

DPH to Distribute Overdose-Reversing Medication Naloxone Friday, Sept. 6 in Millsboro

n response to six suspected overdose deaths, including four in Sussex County, that occurred over the holiday weekend, the Division of Public Health (DPH) will hold a Community Naloxone Training and Distribution event in Millsboro on Friday, Sept. 6, 2019. DPH will distribute free naloxone kits to members of the public from 10 a.m. to 2 p.m. at Millsboro Fire Company, 109 East State St., Millsboro, DE 19966.




naloxone

Wider Use of Naloxone Could Cut Deaths From Drug Overdoses: CDC

Title: Wider Use of Naloxone Could Cut Deaths From Drug Overdoses: CDC
Category: Health News
Created: 4/24/2015 12:00:00 AM
Last Editorial Review: 4/27/2015 12:00:00 AM




naloxone

Attorney General Holder Announces Plans for Federal Law Enforcement Personnel to Begin Carrying Naloxone

In a new memorandum released Friday, Attorney General Eric Holder urged federal law enforcement agencies to identify, train and equip personnel who may interact with a victim of a heroin overdose with the drug naloxone. This latest step by the Attorney General will pave the way for certain federal agents -- such as emergency medical personnel -- to begin carrying the potentially life-saving drug known for effectively restoring breathing to a victim in the midst of a heroin or opioid overdose



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