drug

Utilizing solid-state nanopore sensing for high-efficiency and precise targeted localization in antiviral drug development

Analyst, 2024, 149,5313-5319
DOI: 10.1039/D4AN00946K, Paper
Wei Xu, Lichun Zou, Haiyan Wang, Changhui Xu, Qinyang Fan, Jingjie Sha
The efficient identification and validation of drug targets are paramount in drug discovery and development.
The content of this RSS Feed (c) The Royal Society of Chemistry




drug

Crafting porous nanoscaled architecture as a potential frontier for drug delivery

Mol. Syst. Des. Eng., 2024, 9,1085-1106
DOI: 10.1039/D4ME00098F, Review Article
Koyeli Girigoswami, Pragya Pallavi, Agnishwar Girigoswami
Porous nanostructures exhibit remarkable nanoplatforms for payload delivery to diseased cells with high loading capacity, favorable release profiles, improved hemocompatibility, biocompatibility, and safe clearance after biodegradation.
The content of this RSS Feed (c) The Royal Society of Chemistry




drug

Investigating drug abuse in hair samples using the electrospun PEDOT–CNT nanostructure along with EA-IT-SPME

New J. Chem., 2024, 48,7277-7286
DOI: 10.1039/D4NJ00023D, Paper
Negar Sabahi Moosavi, Yadollah Yamini, Payam Osooli
Electrospinning, a simple and low-cost method, is one of the best ways to produce nanoscale porous adsorbents.
The content of this RSS Feed (c) The Royal Society of Chemistry




drug

Regulating water decontamination and food safety by a reusable, nano-sized MOF@cotton@chitosan composite through nanomolar detection of the drug nitroxinil and organoarsenic feed additive p-arsanilic acid

Environ. Sci.: Nano, 2024, Advance Article
DOI: 10.1039/D4EN00066H, Paper
Subhrajyoti Ghosh, Debjit Mal, Shyam Biswas
MOF@cotton@chitosan composite for nanomolar fluorescence sensing of nitroxinil drug and p-arsanilic acid in real samples is presented.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




drug

Biomass@MOF nanohybrid materials for competitive drug adsorption: analysis by conventional macroscopic models and statistical physical models

Environ. Sci.: Nano, 2024, 11,1543-1558
DOI: 10.1039/D3EN00843F, Paper
Bryan Fernando Rivadeneira-Mendoza, Luis Santiago Quiroz-Fernández, Fausthon Fred da Silva, Rafael Luque, Alina M. Balu, Joan Manuel Rodríguez-Díaz
This study discloses the design of nanohybrid Biomass@MOF resulting from the functionalization of a hydrochar (HC) through hydrothermal treatment (HT) of corn cob residues and MIL-53(Al).
The content of this RSS Feed (c) The Royal Society of Chemistry




drug

Rational construction of micro-plate-like iron oxide/aluminium oxide-fabricated screen-printed carbon electrode for the electrochemical detection of the antiandrogen drug

Environ. Sci.: Nano, 2024, 11,1521-1532
DOI: 10.1039/D3EN00808H, Paper
Sivakumar Musuvadhi Babulal, Nandini Nataraj, Tse-Wei Chen, Shen Ming Chen, Bih-Show Lou, Arshad Mehmood Abbasi, Amal M. Al-Mohaimeed, Mohamed Soliman Elshikh, Jaysan Yu
An improved electrochemical sensing platform with a vital strategy for NTM antiandrogen drug detection in real environmental and biofluid samples.
The content of this RSS Feed (c) The Royal Society of Chemistry




drug

A zwitterionic salt–cocrystal: in vitro insights from niraparib tosylate, an anti-cancer drug

CrystEngComm, 2024, Advance Article
DOI: 10.1039/D4CE00114A, Paper
Ramesh Reddy Mudda, Ramesh Devarapalli, Arijit Das, Pulla Reddy Lakkireddy, C. Malla Reddy, Ramanaiah Chennuru
Schematic representation showing nomenclature of different cocrystals.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




drug

Researchers harness AI to repurpose existing drugs for pain management




drug

Indian scientists develop method to create hydrogels to boost drug delivery




drug

Design, synthesis, biological evaluation and molecular docking studies of quinoline-anthranilic acid hybrids as potent anti-inflammatory drugs

Org. Biomol. Chem., 2024, Advance Article
DOI: 10.1039/D4OB00040D, Paper
Sidra Siddique, Khalid Hussain, Naureen Shehzadi, Muhammad Arshad, Muhammad Nadeem Arshad, Sadaf Iftikhar, Farhat Saghir, Ayisha Shaukat, Muhammad Sarfraz, Nisar Ahmed
Despite the high global prevalence, rheumatoid arthritis lacks a satisfactory treatment.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




drug

Natural products from human microbiome: an emergent frontier in organic synthesis and drug discovery

Org. Biomol. Chem., 2024, Accepted Manuscript
DOI: 10.1039/D4OB00236A, Review Article
Goverdhan Mehta, Saumitra Sengupta, Srihari Pabbaraja
Often referred to as “second genome”, human microbiome is at the epicenter of a complex inter-habitat biochemical network, such as the “gut-brain axis”, which have emerged as significant determinant of...
The content of this RSS Feed (c) The Royal Society of Chemistry




drug

Why did the Centre sanction a 50% hike in prices of commonly-used drugs?

According to the government the recent 50% hike in prices of eight drugs was sanctioned keeping in mind the larger public interest and to ensure continued availability of drugs




drug

Drugs regulator finds 49 samples not of standard quality, manufacturers asked to withdraw their products

Four spurious drugs were also found and action has been initiated against the makers, the DCGI said




drug

National Pharmaceutical Pricing Authority directs firms to cut prices of three anti-cancer drugs

Govt. had earlier scrapped customs duty on Trastuzumab, Osimertinib and Durvalumab and also reduced GST rates on them




drug

Understanding orphan drugs: what are they, how are they classified and what are their challenges in the Indian context

While orphan drugs are crucial to treating rare, sometimes debilitating conditions, the high cost of their research and development is a major barrier to their development in India





drug

Empowering Pharma with AI, Analytics: Accelerating Drug Discovery, Optimizing Healthcare Outcomes By Rajesh Munirathnam

While AI is making significant strides in healthcare, it is also transforming other industries, such as insurance.




drug

Mythbusting - Dr. Carl Hart Debunks Drug Myths

Scientist Dr. Carl Hart, author of the forthcoming book "Drug Use for Grown-ups," helps debunk (and confirm!) some common myths about drugs.. Dr. Hart has spent his career researching the effects of drugs on the body and is here to help us understand some common misunderstandings. Is marijuana really a gateway drug? Is the opioid crisis getting worse? Are drugs more addictive than alcohol?




drug

Longevity Genes & The Search For An Anti-Aging Drug | The Future of Ageing | WIRED

"Imagine a world, where you live to an old age, over 100 years old, but you are healthy all the time, you are doing fun things, and you are spending time with your family, and one day you don't wake up. Wouldn't it be wonderful for the individual, for the families, for the economy, for everyone?". In episode one of Wired UK's four-part documentary series, we delve into the future of ageing; why are certain people able to live longer than others? What makes centenarians unique? How are they able to reach the age that they have? Taking in expert analysis and insights from Dr. Nir Barzilai, Director of the Institute for Ageing Research at the Albert Einstein College of Medicine, this series aims to explore the science behind longevity genes and what this research could mean for the future of humankind. Subscribe to WIRED UK ► https://www.youtube.com/wireduk?sub_confirmation=1 Visit the WIRED website ► https://www.wired.co.uk Subscribe to WIRED Magazine ► https://www.wired.co.uk/subscribe Sign up for one or more of our WIRED newsletters: https://www.wired.co.uk/newsletters CONNECT WITH WIRED Facebook: https://www.facebook.com/wireduk Instagram: https://www.instagram.com/wireduk Twitter: https://twitter.com/wireduk LinkedIn: https://www.linkedin.com/company/wired-uk ABOUT WIRED WIRED brings you the future as it happens - the people, the trends, the big ideas that will change our lives. An award-winning printed monthly and online publication. WIRED is an agenda-setting magazine offering brain food on a wide range of topics, from science, technology and business to pop-culture and politics.




drug

Metformin: The First Anti-Ageing Drug? | The Future of Ageing | WIRED

"Average life expectancy is now in the 80's in most developed countries, so we are losing out on 15-20 years of life for most people". In episode two of Wired UK's four-part documentary series, we head to New York City to talk to Dr. Nir Barzilai and Dr. Ana Maria Cuervo, directors at the Institute for Ageing Research at the Albert Einstein College of Medicine, about their extensive and detailed work on the biological, physiological and functional processes of ageing. We also discuss the institute's exploration into what genes are resilient to the negative aspects of ageing, as well as what impact the so-called 'miracle drug' Metformin could potentially have. Subscribe to WIRED UK ► https://www.youtube.com/wireduk?sub_confirmation=1 Visit the WIRED website ► https://www.wired.co.uk Subscribe to WIRED Magazine ► https://www.wired.co.uk/subscribe Sign up for one or more of our WIRED newsletters: https://www.wired.co.uk/newsletters CONNECT WITH WIRED Facebook: https://www.facebook.com/wireduk Instagram: https://www.instagram.com/wireduk Twitter: https://twitter.com/wireduk LinkedIn: https://www.linkedin.com/company/wired-uk ABOUT WIRED WIRED brings you the future as it happens - the people, the trends, the big ideas that will change our lives. An award-winning printed monthly and online publication. WIRED is an agenda-setting magazine offering brain food on a wide range of topics, from science, technology and business to pop-culture and politics.




drug

Albumin nanocapsules and nanocrystals for efficient intracellular drug release

Nanoscale Horiz., 2024, 9,1978-1989
DOI: 10.1039/D4NH00161C, Communication
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Sharafudheen Pottanam Chali, Jaana Westmeier, Franziska Krebs, Shuai Jiang, Friederike Pauline Neesen, Doğa Uncuer, Mario Schelhaas, Stephan Grabbe, Christian Becker, Katharina Landfester, Kerstin Steinbrink
The present study demonstrates that albumin-coated drug nanocrystals represent a highly efficacious novel approach for the controlled intracellular release of drugs with limited solubility in immune cells.
The content of this RSS Feed (c) The Royal Society of Chemistry




drug

Correction: Enhancing the chemotherapeutic efficacy of platinum prodrug nanoparticles and inhibiting cancer metastasis by targeting iron homeostasis

Nanoscale Horiz., 2024, 9,2067-2068
DOI: 10.1039/D4NH90069C, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Fang Ding, Lingpu Zhang, Hao Chen, Haiqin Song, Shiguo Chen, Haihua Xiao
The content of this RSS Feed (c) The Royal Society of Chemistry




drug

This common heart drug may be unnecessary, lead to depression in some patients: Study




drug

China sends Ebola drug




drug

Ebola drug to be tested




drug

Cipla wins $189 m Global Fund tender for AIDS drugs

Contract is effective from January 1 and will run for 3 years




drug

India flooded with unsafe fixed dose combination drugs

Many unapproved FDC formulations contain banned, restricted, or never approved drugs




drug

Curcumin, a wonder drug in waiting




drug

Drug-resistant bug Klebsiella causes worry

In some cases, even colistin has failed to kill it.




drug

Quality control for AYUSH drugs




drug

Diabetes drug may raise bladder cancer risk: study

Compared with no thiazolidinedione use, pioglitazone associated with an overall 63 p.c. increased risk




drug

Prices of 42 essential drugs slashed by 15%




drug

Novel drug compound inhibits skin cancer in mice, finds study




drug

IISc Ph.D. student wins award in Berlin for a device that detects drug-resistant tuberculosis

Entire infrastructure could fit into a small briefcase, and it is expected to provide the much-needed breakthrough in the field of TB diagnostics




drug

Trump’s call to Modi on Covid-related drug spotlights two Indian drugmakers

This, even as DGFT bans export of hydroxychloroquine




drug

Of diets and weight-loss drugs, India could take a leaf out of Japan’s experience, says author 

Obesity has “exploded” around the world, and it’s not because people are lazy or weak-willed - Johann Hari, Author




drug

Combating superbugs: How Indian drugmakers can address the global shortfall in antibiotic development

Emphasising the importance of expanding access to high-burden regions, the report calls for strategic initiatives to enable the production and distribution of life-saving antibiotics and antifungals




drug

AIADMK leader seeks DCGI action on spurious drugs




drug

40 new drug stores granted licence to sell Tamiflu tablets in Delhi




drug

Show cause notices sent to 10 Indian doctors for receiving payment from drug companies




drug

Sikkim inches closer to Mumbai in multi-drug-resistant TB cases

Mumbai, with a population of 1.3 crore, recorded over 27,000 TB cases last year of which 3,300 were MDR-TB cases.




drug

Coimbatore City Police bust prescription drug peddling network




drug

Coimbatore City Police intensify efforts to curb prescription drug peddling




drug

Market definition in the pharmaceutical industry: a case of drugs hopping antitrust markets? [electronic journal].




drug

Disruption of lipid metabolism to induce ferroptosis using multifunctional fibrate-Pt(IV) prodrugs for cancer treatment

Inorg. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QI00386A, Research Article
Peng Sun, Jia-Qian Wang, Qiang Xie, Xuan-Lin Ren, Xin Qiao, Jing-Yuan Xu
Two multifunctional fibrate-Pt(IV) prodrugs, 1 and 3, bearing lipid-modulating agents, exhibited impressive anticancer activity by triggering ferroptosis and apoptosis.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




drug

Why drugmakers are dialing C for current good manufacturing practices

For the industry under scrutiny over quality concerns, cGMP requires immediate attention




drug

Drugmakers chart a specialised course to navigate choppy waters

India’s pharma industry is moving from volume to value, investing in quality manufacturing 




drug

PLI, plugging chinks in the country’s manufacturing armour for drugs and devices

 Call for simplification of licencing regimes gets louder even as benefits become tangible 




drug

Zydus Cadila gets USFDA nod for drug trials to treat chemotherapy-induced anemia




drug

Ceiling prices of 8 common drugs raised by 50%, these medicines treat asthma, tuberculosis, others...

The National Pharmaceutical Pricing Authority (NPPA) has sanctioned the ceiling price hike for 11 formulations by 50 per cent in response to representations from drug makers.