drug

HIV-Preventive Drug-PrEP's Usage Barriers Among Young Men

Young men who have sex with other men have limited knowledge and awareness of the medlinkHIV/medlink prevention medlinkdrug- PrEP/medlink and




drug

New Study Links HIV Drug Abacavir to Higher Cardiovascular Risk

Current or previous use of the medlinkantiretroviral drug/medlink (ARV) abacavir was linked to an increased risk of major adverse cardiovascular events




drug

Amyotrophic Lateral Sclerosis Drug May Help Battle Against Incurable Glioblastoma

Drugs used to slow Amyotrophic lateral sclerosis (ALS) progression may also suppress self-renewing cancerous stem cells in grade 4 glioblastoma, the most




drug

Alzheimer's Drug Discovery Foundation Funds Amicus Therapeutics To Advance Pharmacological Chaperone Technology

Alzheimer's Drug Discovery Foundation Funds Amicus Therapeutics To Advance Pharmacological Chaperone Technology




drug

Hepatitis C Drug to be Offered Soon in India at Only One Percent of Its Cost in USA

Patent holder and pharma major Gilead, announced voluntary licences with seven generic drug manufacturers in India to s




drug

AI Driven Drug Discovery for Advanced Pain Management

Approximately one in five Americans experiences chronic pain, and existing medications aren't very promising. Feixiong Cheng, Ph.D, Director of the Genome




drug

Ayurvedic Drug Protects Kidney Damage

Ayurvedic poly-herbal drug called Neeri-KFT can help in kidney recovery, reveals a new study. Patients suffering from Ascites -- a condition




drug

Transcendental Meditation Lowers Death due to Drug-Overdose

Transcendental Meditation (Regd) (TM (Regd) ) and its advanced aspect, the TM-Sidhi (Regd) program, may decrease the rising deaths due to opioids and other drugs. The




drug

Is a Traditional Medicine Plant the Answer to Drug-Resistant Malaria?

Medicinal Labrador tea plant compounds were found to offer protective activity against the parasite responsible for medlinkmalaria/medlink (!--ref1--).




drug

Traditional Siddha Drugs Show Promise in Combating Anemia

The use of Siddha drug treatment can help reduce medlinkanemia/medlink among adolescent girls as per a study that highlights the potential of traditional




drug

Hospital Sinks: Prime Spot for Multidrug-Resistant Bacteria

A study revealed that the risk of spreading medlinkmultidrug-resistant bacteria/medlink is most pronounced in hospital sinks. These conclusions stem




drug

Natco Pharma and Hetero Receives Indian Drug Regulatory Approval for Hepatitis-C Drug

Two Hyderabad-based drug companies, Natco Pharma and Hetero have received approval for the sale of Hepatitis- C drug from the Drugs Controller General of India (DCGI).




drug

Turing's CEO in Trouble for Planning to Overprice a Free Drug in the US

The most hated CEO in the United States is again planning to increase the price of a drug used to treat Chagas disease in the Latin America.Chagas disease




drug

Soligenix's Drug Shows Potential to Treat Oral Mucositis in Phase 2 Trial

New Jersey-based biopharmaceutical company, Soligenix has revealed that its developing drug has showed positive results against oral mucositis in Phase 2 clinical trial.




drug

USFDA Lifts Clinical Hold On Three Cancer Drugs of Advaxis

Advaxis has announced that the U.S. Food and Drug Administration (FDA) has lifted the clinical hold on IND applications of its three drugs. Advaxis is




drug

Cipla Unveils Generic Version of Oral Hepatitis C Drug in India

Indian drug maker, Cipla has announced that it has released the generic version of Hepatitis C drug, Sofosbuvir in India.The drug will be marketed under




drug

GlaxoSmithKline's Asthma Drug 'Not Cost Effective': Boston-Based Independent Organization

The newly launched asthma drug by the London-based drug maker, GlaxoSmithKline (GSK) is not cost-effective, reports an independent nonprofit organization.




drug

FDA Approves AstraZeneca's Drug to Treat Hyperuricemia Associated With Gout

Zurampic (lesinurad), a drug to treat high levels of uric acid in the blood (hyperuricemia) associated with gout, has been approved by the US Food and




drug

US Drug Company Recalls Children's Cough Syrup in Fear of Overdose

A US pharmaceutical company has recalled its two products due to concerns regarding incorrect markings on the dosage cups.Perrigo Company is voluntarily




drug

FDA Offers Full Approval for Amgen's Blood Cancer Drug 'Krypolis'

The US food and Drug Administration has announced that it has approved Amgen's supplemental new drug application for Kyprolis in combination with dexamethasone




drug

Indian Drug Maker Procures Two Patents for Neurodegenerative Drug

Indian biopharmaceutical company, Suven Life Sciences has secured two patents from two different countries on its new chemical entities (NCE's) for the treatment of several neurodegenerative diseases.




drug

Hemophilia B Drug 'Idelvion' Receives USFDA Approval

A biopharmaceutical company's drug has been approved by the US Food and Drug Administration for treating people with hemophilia B. CSL Behring has




drug

GlaxoSmithKline Stops Sale of Crocin Cold (and) Flu Drug

After the Indian government has banned the sale of fixed dose combination drugs (FDCs) like Corex, Phensedyl and Vicks Action 500 Extra, the pharmaceutical




drug

Novartis Launches Scapho Drug for the Treatment of Psoriasis

Switzerland-based pharmaceutical company, Novartis has launched the drug, Scapho for the treatment of plaque psoriasis in India. Psoriasis is a severe,




drug

Pfizer to Pay (Dollor) 785 Million for Overcharging Anti-Acid Drugs

US drug maker Pfizer has agreed to pay (Dollor) 785 million to settle allegations that one of its units has offered discounts to private purchasers on heartburn




drug

India Grants Patent for Gilead's Hepatitis C Drug

US pharmaceutical giant Gilead has obtained a patent for its Hepatitis C drug from India. This patent could potentially stop affordable copies reaching millions of people in other countries.




drug

Stempeucel for Buerger's Disease Receives Limited Approval from Drug Controller of India

An effective cure for one of the most devastating disease could be in the cards as the Drug Controller of India (DGCI) has granted limited approval for




drug

Shire Receives Breakthrough Therapy Designation for Rare Diseases Drugs

US Food and Drug Administration has granted breakthrough therapy designation for two experimental drugs for rare diseases conducted by the biotechnology company Shire.




drug

Online Course on Prevention of Drug Abuse Launched

Arunachal Pradesh has launched an online certificate course on drug abuse prevention, intending to eradicate narcotics abuse. The 4-month online




drug

Patient Influencers Partnering with Companies for Drug Promotion

During the television show 'The View', Kim Kardashian, who has 255 million followers on Instagram, touted the benefit of migraine drug Nurtec ODT. She




drug

Medicare Program Spent (Dollor) 1.8 Billion in 2019 on Drugs Without Confirmed Clinical Benefits: Study

In 2019, the U.S. federal government expended an estimated (Dollor) 1.8 billion in Medicare funds on medications whose clinical benefits have yet to be confirmed




drug

Naloxone Drug Cost may Keep may Uninsured from Using Life-saving Treatment

The cost of purchasing the opioid antidote naloxone is out of reach for many uninsured Americans. This may keep the treatment from saving more people




drug

GST Council's Bold Move to Slash Taxes on Insurance and Cancer Drugs

The GST Council, led by Finance Minister Nirmala Sitharaman, has formed a Group of Ministers to evaluate reducing GST rates on life and health insurance,




drug

Revealing the effect of host–guest complementarity in supramolecular monofunctional platinum(II) drugs

Inorg. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QI02012J, Research Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Shib Shankar Paul, Jan Novotný, Jakub Jakubec, Kateřina Petrláková, Pia Jurček, Klára Rašková, Michaela Kuchynka, Michal Masařík, Petr Kulhánek, Radek Marek
Host–guest complementarity is shown to influence the chemical activation by aquation and the biological activity of platinum(II) drugs.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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drug

Correction: Unexpected in crystallo reactivity of the potential drug bis(maltolato)oxidovanadium(IV) with lysozyme

Inorg. Chem. Front., 2024, 11,8147-8147
DOI: 10.1039/D4QI90073A, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Maddalena Paolillo, Giarita Ferraro, Irene Cipollone, Eugenio Garribba, Maria Monti, Antonello Merlino
The content of this RSS Feed (c) The Royal Society of Chemistry




drug

Deciphering fibroblast-induced drug resistance in non-small cell lung carcinoma through patient-derived organoids in agarose microwells

Lab Chip, 2024, 24,2025-2038
DOI: 10.1039/D3LC01044A, Paper
Qiyue Luan, Ines Pulido, Angelique Isagirre, Julian Carretero, Jian Zhou, Takeshi Shimamura, Ian Papautsky
Agarose microwell platform for modeling lung carcinoma using patient-derived tissues to decipher cancer associated fibroblast-induced drug resistance.
The content of this RSS Feed (c) The Royal Society of Chemistry




drug

Vascularized tissue on mesh-assisted platform (VT-MAP): a novel approach for diverse organoid size culture and tailored cancer drug response analysis

Lab Chip, 2024, 24,2208-2223
DOI: 10.1039/D3LC01055D, Paper
Open Access
Jungseub Lee, Sangmin Jung, Hye Kyoung Hong, Hyeonsu Jo, Stephen Rhee, Ye-Lin Jeong, Jihoon Ko, Yong Beom Cho, Noo Li Jeon
VT-MAP, a novel in vitro platform, offers better physiological reflection through the vascularized organoid. This advancement supports drug assessment with deeper insights into cancer biology through correlation between morphology and drug effects.
The content of this RSS Feed (c) The Royal Society of Chemistry




drug

Drug testing of monodisperse arrays of live microdissected tumors using a valved multiwell microfluidic platform

Lab Chip, 2024, Advance Article
DOI: 10.1039/D4LC00016A, Paper
Ethan J. Lockhart, Lisa F. Horowitz, Adán Rodríguez, Songli Zhu, Tran Nguyen, Mehdi Mehrabi, Taranjit S. Gujral, Albert Folch
A microfluidic platform was developed that hydrodynamically traps microdissected cuboids for selective drug treatments and isolates conditions with thermoplastic valves.
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The content of this RSS Feed (c) The Royal Society of Chemistry




drug

Hydrogen bonding enhanced drug–polymer interaction for efficient drug loading and delivery

Soft Matter, 2024, Advance Article
DOI: 10.1039/D4SM00003J, Communication
Xiaotian Qu, Junran Li, Yishu Yu, Jie Yang
A carrier design strategy of hydrogen bonding enhanced drug–carrier interaction is developed to prepare a polymeric nanomedicine with high drug loading content and superb loading efficiency as well as tunable nanostructures.
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The content of this RSS Feed (c) The Royal Society of Chemistry




drug

Harnessing the power of natural deep eutectic solvents (choline chloride/sucrose) and polypropylene glycol in the formation of aqueous biphasic systems and the application of these systems in drug extraction

RSC Adv., 2024, 14,12349-12359
DOI: 10.1039/D3RA07066B, Paper
Open Access
Fariba Ghaffari, Mohammed Taghi Zafarani-Moattar, Hemayat Shekaari
In recent times, there has been considerable interest in utilizing aqueous biphasic systems (ABSs) containing natural deep eutectic solvents (NADESs) for the extraction of various substances.
The content of this RSS Feed (c) The Royal Society of Chemistry




drug

Construction of glutathione-responsive paclitaxel prodrug nanoparticles for image-guided targeted delivery and breast cancer therapy

RSC Adv., 2024, 14,12796-12806
DOI: 10.1039/D4RA00610K, Paper
Open Access
Weiwei Ma, Qiufeng Zhao, Shilong Zhu, Xinyue Wang, Chuangchuang Zhang, Daming Ma, Na Li, Yanyan Yin
HA-coated redox sensitive visualized nano-prodrug HA/TPE-CS-SS-PTX were exploited in order to highly efficient treatment of cancer and real-time monitoring of drug localization.
The content of this RSS Feed (c) The Royal Society of Chemistry




drug

Correction: Photocatalytic degradation of drugs and dyes using a machine learning approach

RSC Adv., 2024, 14,12983-12983
DOI: 10.1039/D4RA90045F, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Ganesan Anandhi, M. Iyapparaja
The content of this RSS Feed (c) The Royal Society of Chemistry




drug

Retraction: Biologically responsive, sustainable release from metallo-drug coordinated 1D nanostructures

J. Mater. Chem. B, 2024, 12,11042-11042
DOI: 10.1039/D4TB90170C, Retraction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Naohiro Kameta, Soo Jin Lee, Mitsutoshi Masuda, Toshimi Shimizu
The content of this RSS Feed (c) The Royal Society of Chemistry




drug

Photoresponsive prodrug-based liposomes for controllable release of the anticancer drug chlorambucil

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01620C, Paper
Xiaoting Wang, Guangtian Suo, Shinan Ma, Chunxi Yang, Chunyan Bao
A photoresponsive lipid prodrug was designed to form nanomedicines for accurate and controllable drug release in response to light irradiation.
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The content of this RSS Feed (c) The Royal Society of Chemistry




drug

Multimodal layer-by-layer nanoparticles: a breakthrough in gene and drug delivery for osteosarcoma

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01541J, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Eugenia Crisafulli, Annachiara Scalzone, Chiara Tonda-Turo, Joel Girón-Hernández, Piergiorgio Gentile
This study explored biodegradable nanoparticles for treating osteosarcoma. Co-delivery of miRNA-34a, doxorubicin, and resveratrol by LbL nanocoating enhanced apoptosis and cell disruption with promise to improve efficacy and reduce drug resistance.
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drug

Drug-delivery and biological activity in colorectal cancer of a supramolecular porous material assembled from heptameric chromium-copper-adenine entities

J. Mater. Chem. B, 2024, 12,11156-11164
DOI: 10.1039/D4TB01521E, Paper
Sandra Mena-Gutiérrez, Ekain Maiza-Razkin, Jon Pascual-Colino, Marcos J. Araúzo-Bravo, Garikoitz Beobide, Oscar Castillo, Ainara Castellanos-Rubio, Daniela Gerovska, Antonio Luque, Sonia Pérez-Yáñez
Supramolecular metal-organic porous materials as drug delivery systems, modulation of the release kinetics using cholesterol as pore blocking agent and its impact on colorectal cancer cell cultures: cytotoxicity and RNA-seq transcriptomics studies.
The content of this RSS Feed (c) The Royal Society of Chemistry




drug

Nanobiopolymers in cancer therapeutics: advancing targeted drug delivery through sustainable and controlled release mechanisms

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB00599F, Review Article
Shikha Gulati, Nabeela Ansari, Yamini Moriya, Kumud Joshi, Disha Prasad, Gargi Sajwan, Shefali Shukla, Sanjay Kumar, Rajender S. Varma
Nanobiopolymers in cancer therapeutics offer sustainable and targeted drug delivery with controlled release, enhancing treatment efficacy while ensuring sustainability and biodegradability for improved patient care.
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drug

Development of enzymatically crosslinked natural deep eutectogels: versatile gels for enhanced drug delivery

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01672F, Paper
Liane Meneses, Dimitra Antonia Bagaki, Ana Roda, Alexandre Paiva, Ana Rita C. Duarte
We propose a new injectable eutectogel prepared by enzymatic crosslinking, using NADES, betaine : glycerol (2 : 1), as solvent. The potential of using this material with improved rheological properties as drug delivery system, has also been evaluated.
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drug

Quantum DFT analysis and molecular docking investigation of various potential breast cancer drugs

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01803F, Paper
Ashraf Ayub, Ankit Raj Tyagi, Sunil Kumar Srivastava, Pranveer Singh
Breast cancer is the most often diagnosed and deadliest type of cancer in the world. These days, the world is facing the threat of breast cancer. It is essential to...
The content of this RSS Feed (c) The Royal Society of Chemistry




drug

Advancing cancer therapy with a heptamethine carbocyanine dye-conjugated radionuclide drug

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01798F, Paper
Mingxing Huang, Weichen Wang, Yingwei Wang, Rang Wang, Lili Pan, Xin Li, Bo Li, Jingsong Zhang, Ruoxiang Wang, Yi Zhang, Rong Tian
Malignant tumors pose substantial treatment challenges due to their heterogeneity, metastatic potential, and therapeutic resistance, underscoring the urgent need for more effective treatment options.
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