drug

Kyowa Kirin invests in MEI Pharma's blood-cancer drug




drug

MOMA Therapeutics launches with $86 million series A to drug molecular machines




drug

i2O launches for ionic liquid–based drug delivery




drug

India aims to be a global hub for drug production




drug

NDMA, a contaminant found in multiple drugs, has industry seeking sources and solutions

The presence of the probable carcinogen has prompted drugmakers to issue recall after recall. What risk does it pose, what's the chemistry behind it, and how are drugmakers going to stop the contamination?




drug

Nitrome raises $38 million to drug Parkinson's enzyme




drug

Rome Therapeutics launches to probe junk DNA for cancer drug discovery

Biotech veteran Rosana Kapeller co-founded the start-up, which raised $50 million to develop small-molecule drugs




drug

Does the FDA's authorization for chloroquine impede clinical trials for COVID-19 drugs?

Despite the hype, support for the use of chloroquine and its relative hydroxychloroquine outside a clinical trial remains mixed




drug

Rome Therapeutics launches to probe junk DNA for cancer drug discovery

Biotech veteran Rosana Kapeller cofounded the start-up, which raised $50 million to develop small-molecule drugs




drug

Cell studies suggest some repurposed drugs could block replication of SARS-CoV-2

The experiments follow up on an earlier study that identified 69 compounds that could disrupt possible interactions between viral and human proteins




drug

Cell studies suggest some repurposed drugs could block replication of SARS-CoV-2

The experiments follow up on an earlier study that identified 69 compounds that could disrupt possible interactions between viral and human proteins




drug

Ventus Therapeutics launches to drug inflammasomes, cGAS, and more

The Versant-founded start-up raised $60 million to develop small molecules that target innate immune system proteins




drug

Evonik to boost drug actives capacity in Germany

Project joins a steady flow of investment boosted by heightened supply chain concerns




drug

SRI and Exscientia partner on AI-assisted cancer drug discovery




drug

Praxis Precision Medicines launches with $100 million to develop neuroscience drugs




drug

Drug targeting [electronic resource] : strategies, principles, and applications / edited by G.E. Francis and Cristina Delgado

Totowa, N.J. : Humana Press, [2000]




drug

Drug discovery and evaluation [electronic resource] : safety and pharmacokinetic assays / H. Gerhard Vogel (ed.) ; Franz Jakob Hock, Jochen Maas, Dieter Mayer (co-editors)

Berlin ; New York : Springer, [2006]




drug

Drug and biological development [electronic resource] : from molecule to product and beyond / editor, Ronald P. Evens

New York ; London : Springer, 2007




drug

Simultaneous ozonation of 90 organic micropollutants including illicit drugs and their metabolites in different water matrices

Environ. Sci.: Water Res. Technol., 2020, Accepted Manuscript
DOI: 10.1039/D0EW00260G, Paper
Open Access
Garyfalia A. Zoumpouli, Fernanda Siqueira Souza, Bruce Petrie, Liliana Féris, Barbara Kasprzyk-Hordern, Jannis Wenk
The ozonation of 90 chemically diverse organic micropollutants (OMPs) including four classes of illicit drugs and their metabolites was studied in pure buffered water, tap water and wastewater effluent at...
The content of this RSS Feed (c) The Royal Society of Chemistry




drug

[ASAP] Cell Type-Dependent Specificity and Anti-Inflammatory Effects of Charge-Reversible MSNs-COS-CMC for Targeted Drug Delivery in Cervical Carcinoma

Molecular Pharmaceutics
DOI: 10.1021/acs.molpharmaceut.0c00004




drug

[ASAP] Dissipative Particle Dynamics Aided Design of Drug Delivery Systems: A Review

Molecular Pharmaceutics
DOI: 10.1021/acs.molpharmaceut.0c00175




drug

[ASAP] Prodrug Approach for Posterior Eye Drug Delivery: Synthesis of Novel Ganciclovir Prodrugs and in Vitro Screening with Cassette Dosing

Molecular Pharmaceutics
DOI: 10.1021/acs.molpharmaceut.0c00037




drug

[ASAP] Repurposing of Drugs Is a Viable Approach to Develop Therapeutic Strategies against Central Nervous System Related Pathogenic Amoebae

ACS Chemical Neuroscience
DOI: 10.1021/acschemneuro.9b00613




drug

Leung's encyclopedia of common natural ingredients : used in food, drugs, and cosmetics / Ikhlas A. Khan, Ehab A. Abourashed

Khan, I. A




drug

Ultrafast synthesis of 2-(benzhydrylthio)benzo[d]oxazole, an antimalarial drug, via an unstable lithium thiolate intermediate in a capillary microreactor

React. Chem. Eng., 2020, 5,849-852
DOI: 10.1039/D0RE00038H, Communication
Bandaru T. Ramanjaneyulu, Shinde Vidyacharan, Gwang-Noh Ahn, Dong-Pyo Kim
We present an ultrafast approach for the synthesis of 2-(benzhydrylthio)benzo[d]oxazole, an antimalarial drug, in 75% yield from benzo[d]oxazole-2-thiol and benzhydryl bromide via an unstable lithium thiolate intermediate in the presence of n-BuLi.
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drug

[ASAP] Prediction of Amphiphilic Cell-Penetrating Peptide Building Blocks from Protein-Derived Amino Acid Sequences for Engineering of Drug Delivery Nanoassemblies

The Journal of Physical Chemistry B
DOI: 10.1021/acs.jpcb.0c01618




drug

Pfizer to outsource some drug production, focus on coronavirus vaccine

If successful, Pfizer said it hopes to receive emergency use authorization from the U.S. Food and Drug Administration as early as October




drug

Kaempferol modulates TCDD- and t-BHQ-induced drug-metabolizing enzymes and luteolin enhances this effect

Food Funct., 2020, 11,3668-3680
DOI: 10.1039/C9FO02951F, Paper
Tomoya Kitakaze, Atsushi Makiyama, Rika Nakai, Yuki Kimura, Hitoshi Ashida
Co-treatment with kaempferol and luteolin inhibits AhR- and Nrf2-induced expression of drug-metabolizing enzymes.
The content of this RSS Feed (c) The Royal Society of Chemistry




drug

Mechanisms for Lactobacillus rhamnosus treatment of intestinal infection by drug-resistant Escherichia coli

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00128G, Paper
Na Li, Bing Pang, Junjun Li, Guanwen Liu, Xiaoguang Xu, Dongyan Shao, Chunmei Jiang, Baowei Yang, Junling Shi
Reducing the viability of pathogens may also play an important role for the therapeutic effects of Lactobacillus rhamnosus SHA113 against multiple-drug-resistant E. coli, as well as influencing on the intestinal integrity and functions of animals.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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drug

I will eradicate drug menace in 4 weeks: Amarinder Singh

Interview with Punjab Congress President




drug

Indian-origin scientist identifies four possible drugs to treat Covid-19

Indian-origin scientist identifies four possible drugs to treat Covid-19




drug

'New drug combo shows promise against Covid'

'New drug combo shows promise against Covid'




drug

Coronavirus | Phase-2 trial with three drugs offers hope

Testing in Hong Kong hospitals shows the regimen clears coronavirus in 7 days in the mildly ill.




drug

[ASAP] Licochalcone A Selectively Resensitizes ABCG2-Overexpressing Multidrug-Resistant Cancer Cells to Chemotherapeutic Drugs

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.9b01022




drug

Implementation of Medicare Part D and Nondrug Medical Spending for Elderly Adults With Limited Prior Drug Coverage

Interview with J. Michael McWilliams, MD, Phd, author of Implementation of Medicare Part D and Nondrug Medical Spending for Elderly Adults With Limited Prior Drug Coverage




drug

Universal Screening and Drug Treatment of Dyslipidemia in Children and Adolescents

Interview with Frederick P. Rivara, MD, MPH, author of Universal Screening and Drug Treatment of Dyslipidemia in Children and Adolescents




drug

Chronic Care Management for Dependence on Alcohol and Other Drugs

Interview with Richard Saitz, MD, MPH, author of Chronic Care Management for Dependence on Alcohol and Other Drugs




drug

Calcium-Channel Blocker-Clarithromycin Drug Interactions and Acute Kidney Injury

Interview with Amit X. Garg, MD, PhD, author of Calcium-Channel Blocker-Clarithromycin Drug Interactions and Acute Kidney Injury




drug

Long-term Drug Treatment for Obesity: A Systematic and Clinical Review

Interview with Susan Z. Yanovski, MD, author of Long-term Drug Treatment for Obesity: A Systematic and Clinical Review




drug

Using Multiplexed Assays of Oncogenic Drivers in Lung Cancers to Select Targeted Drugs

Interview with Mark G. Kris, MD, author of Using Multiplexed Assays of Oncogenic Drivers in Lung Cancers to Select Targeted Drugs




drug

Screening and Brief Intervention for Drug Use in Primary Care

Interview with Richard Saitz, MD, MPH, author of Screening and Brief Intervention for Drug Use in Primary Care






drug

Arabian drugs in early medieval Mediterranean medicine / Zohar Amar and Efraim Lev

Rotch Library - RS180.A65 A43 2018




drug

[ASAP] Drug Loading and Dissolution Properties of Dalcetrapib–Montmorillonite Nanocomposite Microparticles

Organic Process Research & Development
DOI: 10.1021/acs.oprd.9b00460




drug

[ASAP] Enzymatic Preparation of the Chiral (<italic toggle="yes">S</italic>)-Sulfoxide Drug Esomeprazole at Pilot-Scale Levels

Organic Process Research & Development
DOI: 10.1021/acs.oprd.0c00115




drug

A biodegradable CO2-based polymeric antitumor nanodrug via a one-pot surfactant- and solvent-free miniemulsion preparation

Biomater. Sci., 2020, 8,2234-2244
DOI: 10.1039/C9BM01931F, Paper
Qiaojie Luo, Xiaojun Li, Ying Wang, Jianfang He, Qiao Zhang, Pengfei Ge, Xia Cai, Qiang Sun, Weipu Zhu, Zhiquan Shen, Xiaodong Li
A biodegradable CO2-based polymeric nanodrug is obtained via a surfactant- and solvent-free miniemulsion preparation, which can be concentrated at tumor site by EPR and releases the encapsulated drug through pH responsiveness.
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drug

A polymeric nanocarrier with a tumor acidity-activatable arginine-rich (R9) peptide for enhanced drug delivery

Biomater. Sci., 2020, 8,2255-2263
DOI: 10.1039/D0BM00069H, Paper
Liting Zhang, Chengtao Jiang, Fanjun Zeng, Haiyu Zhou, Dongdong Li, Xinyu He, Song Shen, Xianzhu Yang, Jun Wang
The cell-penetrating function of R9 peptide of DA@R9-NPDOX was masked in the blood circulation, while reactivated in tumor tissue for enhanced tumor cellular uptake.
The content of this RSS Feed (c) The Royal Society of Chemistry




drug

Tumor-targeting peptide functionalized PEG-PLA micelles for efficient drug delivery

Biomater. Sci., 2020, 8,2274-2282
DOI: 10.1039/C9BM02036E, Paper
Yue Cai, Zhuomin Xu, Qi Shuai, Fangtao Zhu, Jiao Xu, Xin Gao, Xuanrong Sun
PEG-PLA micelles are modified with F3 peptides, thus endowing the micelles with active-targeting ability due to the nucleolin-binding ability of the F3 peptides.
The content of this RSS Feed (c) The Royal Society of Chemistry




drug

High antimicrobial photodynamic activity of photosensitizer encapsulated dual-functional metallocatanionic vesicles against drug-resistant bacteria S. aureus

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00323A, Paper
Bunty Sharma, Gurpreet Kaur, Ganga Ram Chaudhary, Santosh L. Gawali, P. A. Hassan
Developments in the field of photodynamic therapy (PDT) are being made by investigating appropriate photosensitizers (PSs) and enhancing the penetration effect of light by developing new metallocatanionic vesicles.
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