India travel to Australia for their five-Test series - here's everything you need to know including the schedule, squads and how to follow on the BBC.

The BBC’s Mohanad Hashim, in Sudan for the first time since the war began, sees what has happened to his childhood neighbourhood.

BBC Radio London's team of swimmers have completed their part of the 1,000-mile challenge.

Following news that Gary Lineker will leave Match of the Day at the end of the season, how does the BBC cover stories about itself?

Two of the worst fake news purveyors, MSNBC and CNN, both suffered ratings bloodbaths since Donald Trump won his historic victory last week. And it couldn’t happen to any more serving networks. Let’s take the extremist, left-wing MSNBC. Take a look at this delicious drop in ratings: Major Nielsen ratings plunge at MSNBC since Trump […]

The post Fake News MSNBC, CNN Ratings Collapse after Trump’s Massive Win appeared first on The Lid.

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Last week President Obama held a press conference and took questions from a virtual audience in a video webcast.

According to an article written by Chris Lefkow on Yahoo, 67,000 watched the webcast live. The White House website was open for questions for 36 hours before the press conference. 3,607,837 votes were cast for 104,129 submitted questions.

The President answered seven of those questions. One of them was about the legalization of marijuana. Some groups banded together and used the opportunity of this process to submit a high number of questions about that topic, and the despite the fact that vetters tried to avoid that issue, President Obama weighed in with a firm no.

My point has nothing to do with the politics of marijuana.

If I can be so bold as to be self-referential, my first post on this blog was to equate the power of webcasting technology to that of the printing press. The printing press broke the monopoly of a relative few (for example, monks) who had the ability to publish the written word and decide which books were worthy of reproduction and distribution (most often, the bible). The printing press made publishing accessible to the masses.

Regardless of one's politics regarding the issue, I think everyone would agree that those who favor legalizing marijuana are not in the "main stream" or among the more influential interest groups in this country. Yet the President of the United States specifically addressed their question.

The Washington DC press corps is not going to ask that question - rightly or wrongly. But the webcast by-passed the traditional media filter and brought the concerns of this group of people to the attention of our country's chief executive.

How does that translate to the corporate world? Well, what is the value of getting real feedback from the rank and file? What corporation would not benefit from taking their executives out of the bubble on the 40th floor and exposing them to the concerns of the people at the sharp end of the spear?

What is the value of a corporate culture? Most companies do a poor job of communicating and maintaining a corporate culture from the top down. But the best companies leverage webcasting to enable communications from the bottom up and include that feedback in the corporate culture.

There are perhaps a few hundred journalists with access to the President. These journalists are the only way 300,000,000 Americans can hold their leadership accountable between elections. That is, until last Thursday when webcasting allowed the people to submit questions to their President and their President decided to answer them.

President Obama's recent press conference on March 26 was available for online viewing.

According to an article written by Chris Lefkow on Yahoo, 67,000 watched the webcast live. Of course, millions if not tens of millions watched the press conference live on broadcast television so what is the big deal about another 60,000 or so watching on the web?

I wrote about the democratizing effect of using the internet to bypass the Washington press corps and taking questions from the people in my last post.

But there is at least one more point of interest. The Obama press conference exemplifies how video can be used to great effect in the enterprise.

The internet will never supplant television's ability to broadcast to tens of millions of people. Why pay for the bandwidth to replicate the scale and quality of a broadcast platform that already works very well?

But the internet does scale rather well to the needs of the enterprise: an audience of tens of thousands. And there are several "internet television" services that are emerging to deliver video across the corporate network to the employees.

But this begs the question: why should a corporation or organization invest in a network able to deliver video across its enterprise and then settle for pre-recorded video with no interactivity?

It was not the video feed that made the Obama press conference so noteworthy. It was the 104,129 questions that were submitted by the American people. Enterprise video is much more effective when it is combined with interactive rich media features like live questions and answers, live polling, surveys, testing and certification, synchronized PowerPoint, whiteboarding, registration and reporting, etc. Choosing to merely deliver the video - live or on-demand - is choosing to ignore the strengths of webcasting and get the least bang for your buck.

Why invest in servers and hubs and routers and content engines and then settle for a video platform that does not enable interactivity?

According to research done by Steve Vander Haar that he shared in a recent webcast, 68% of executives polled believe streaming video has measurable value only when it is combined with a registration system that enables reporting about who watched.

Registration and reporting adds accountability to internal communications and adds measurable results and lead generation to external communications. Internet television gives that capability away when it simply loops pre-recorded video in a window on one's website.

President Obama's press conference is a template for the effective use of internet video in the enterprise. Just as the televised Nixon vs. Kennedy debate serves as the defining example for understanding the difference between television and radio in politics, I believe this press conference will be regarded similarly for its effect on politics and on business communications.

There are plenty of corporations out there who are already doing a great job with rich media. Some of them are my clients. But the nature of corporate communications is that much of the content is for an internal audience, so there is not an obvious opportunity for organizations to learn from the successes of others. But the Obama press conference lays the formula bare for all to see.

Health and Human Services Secretary Kathleen Sebelius is hosting a webcast at 1 pm EDT today, Friday August 7.

Use the hashtag #HCRQ to ask a question via Twitter or email hhsstudio@hhs.gov.

As the article appeared in TechCrunch...

IVT, a company that produces enterprise-friendly webcasting software, has raised $5.5 million in Series B funding from Syncom Venture Partners with Barshop Ventures, Monitor Ventures and Tudor Ventures participating in the investment round. IVT raised $3 million in Series A funding in 2006.
IVT’s SaaS offering not only helps power webcasts, but also converts multimedia files, such as slideshows, into viewable videos for the web. IVT also offers a YouTube-like hosting and social media site for companies to disseminate videos and webcasts. And the startup has a number of prominent companies that use its webcasting software including Oracle, Dow Chemical, IBM and NEC.

IVT, Inc. has moved its industry-leading MediaPlatform webcasting software platform to the cloud. With MediaPlatform increasingly being used in large-scale webcasts by media producers, as well as Fortune 500 clients, the company is elevating its delivery capacity through a partnership with a tier-1 cloud infrastructure provider.

“Our mission has always been to deliver the best quality of service and enable our clients to produce webcasts at literally any audience size without concern for infrastructure,” said Jim McGovern, Chief Executive Officer of IVT. “Now that cloud-based platforms are gaining widespread acceptance across the IT world, we can give our clients the benefit of switching capacity on and off when required.”

This is not the first time IVT has been ahead of the technology curve in the webcasting industry. The company pioneered the concept of offering webcasting software on a Software-as-a-Service (SaaS) basis with MediaPlatform. With MediaPlatform in the cloud, IVT enables its clients to benefit from what is rapidly emerging as the new paradigm for corporate computing.

In the cloud, MediaPlatform’s web services architecture can more readily serve diverse client needs by integrating with a range of enterprise systems, both cloud-based and on-premises.
The cloud, an approach to computing that places servers and infrastructure in remote, abstracted datacenters, is ideal for webcasting, which is known for unpredictable spikes in system load. By working with a tier-1 cloud infrastructure provider, IVT gains virtually unlimited capacity and world-class security, reliability, redundancy, failover, and load management.

IVT will continue to support the numerous on-premises installations of its software, including major deployments at global enterprises. IVT prides itself on offering its clients the choice between hosted and on-premises options.

MediaPlatform Debuts WebCaster, a Fusion of Performance and UsabilityNew Addition to Webcasting Software Lineup Leverages Cloud Platform for Productivity and Connectivity NEW YORK - STREAMING MEDIA EAST - May 11, 2010 -

MediaPlatform, Inc. (formerly IVT) today unveiled its latest product offering, MediaPlatform WebCaster, cloud-based webcasting software that packs leading edge event management, event customization, and production capabilities into a simple user experience. WebCaster has been built to serve the needs of demanding webcast production professionals as well as non-technical users

"WebCaster is a heavyweight performer with a flyweight price and impact on corporate IT," said Jim McGovern, Chief Executive Officer of MediaPlatform. "Our team has worked hard for over a year to exceed client expectations in virtually every aspect of the webcasting experience."

WebCaster offers a unique mix of best-in-class features, ranging from an intuitive, browser-based user interface and sophisticated reporting to multiple remote presenters and flexible producing teams. WebCaster also offers rich templates with options to customize, total operating system and browser independence, telephony to Flash® Audio input, and iPhone support.
"We went into the development process with a goal of enabling presentations from 'anywhere to anyone,'" said Greg Pulier, Founder and CTO of MediaPlatform, and head of WebCaster's development. "For every feature we considered, our constant question was, 'Will this provide the best possible experience for users at every step of the webcasting process? I am very proud of the work everyone has contributed to this outstanding offering."

With WebCaster, MediaPlatform is further establishing itself as the preferred provider for digital media producers. As the business of producing webcasts for lead generation, training, and conferences continues to expand, MediaPlatform is serving a growing number of top tier digital media production firms. WebCaster is designed to provide producers with a webcasting toolset they can rely upon as they build their production businesses. WebCaster is the newest addition to MediaPlatform's growing portfolio of media production and management offerings.

It complements the company's high-end webcasting product, now known as IVT MediaPlatform, as well as PrimeTime, MediaPlatform's video portal.About MediaPlatform, Inc. MediaPlatform, Inc. (formerly IVT) delivers best-in-class webcasting and media management technology to global enterprises and digital media producers. MediaPlatform's webcasting software enables high-impact presentations for lead generation, corporate communications and training. The company offers organizations the ability to take advantage of scalable cloud-based computing, as well as on-premises deployment, to present and manage rich media. With media management tools built on its platform, the company helps clients derive long term archive value from their investment in media content.

You can see the archive of my discussion with the editors of Simply-communicate about the difference between Web Conferencing and Webcasting by going to their site:

http://www.simply-communicate.com/

They also link to the MediaPlatform White Paper that discusses the same topic.

MediaPlatform WebCaster and Adobe's Flash Media Enterprise Server 4 with Hybrid Flash Multicasting bring a game changing solution to the challenge of delivering video to the enterprise without requiring a seven figure hardware investment for multicasting.

Up to now, solutions for managing streaming video bandwidth issues required networks of expensive hardware, ranging from Enterprise Content Delivery Networks to WAN Acceleration devices. And all of these solutions dictated Windows Media as your video format. Hybrid Flash Multicasting offers a better way; it works seamlessly with traditional IP multicast networks AND it also provides a Peer Assist multicast solution for the parts of your network that are not IP multicast enabled.

Hybrid Flash Multicasting is an outstanding solution because it:

1) allows corporations to continue leveraging the hardware investments they have made and utilize traditional IP Multicasting with Flash instead of Windows Media.

2) allows corporations to reach bandwidth-challenged locations that are not on the multicast WAN or new locations whose networks are not multicast-enabled with a relatively low cost Peer Assist solution (because it does not require new routers and configuration of switches, etc.).

This solution solves the challenge of allowing video to reach 100% of your desktops without requiring a million dollar investment in a new eCDN. And unlike other peering solutions, there is no proprietary agent that has to be propagated to every desktop. All your employees' computers need is the latest Flash player.

Here is how MediaPlatform fits into the equation:

Our WebCaster software is the only streaming video solution that integrates the multicast-enabled Flash player, as well as leveraging Flash's ability to create a cross platform viewing experience, switch between multiple live and pre-recorded video sources, switch bit rates and codecs on the fly, support mobile devices, support H.264 and VP6 to create higher quality video at lower bandwidths, etc. With our software you can take advantage of Flash to upgrade your streaming communications to a more functional format that will work behind the firewall and to the public internet, will work on any browser and operating system, and can deliver content to mobile devices.

Left-wing networks had plenty of bad news for their viewers as former President Donald Trump stormed to victory in the Nov. 5 election. Now, they’re getting plenty of bad news […]

The post Insult to Injury: MSNBC and CNN Suffer Staggering Ratings Plunge Following Trump Victory appeared first on The Western Journal.

Michael Dean
Jul 1, 2001; 42:1007-1017
Thematic Reviews

Ronald M. Krauss
Jan 1, 1982; 23:97-104
Articles

Sir David Attenborough and the BBC Studios Natural History Unit awarded Chatham House Prize 2019 for ocean advocacy News Release sysadmin 18 November 2019

The 2019 Chatham House Prize is awarded to Sir David Attenborough and Julian Hector, head of BBC Studios Natural History Unit, for the galvanizing impact of the Blue Planet II series on tackling ocean plastic pollution.

The subcellular localization of Arf family proteins is generally thought to be determined by their corresponding guanine nucleotide exchange factors. By promoting GTP binding, guanine nucleotide exchange factors induce conformational changes of Arf proteins exposing their N-terminal amphipathic helices, which then insert into the membranes to stabilize the membrane association process. Here, we found that the N-terminal amphipathic motifs of the Golgi-localized Arf family protein, Arfrp1, and the endosome- and plasma membrane–localized Arf family protein, Arl14, play critical roles in spatial determination. Exchanging the amphipathic helix motifs between these two Arf proteins causes the switch of their localizations. Moreover, the amphipathic helices of Arfrp1 and Arl14 are sufficient for cytosolic proteins to be localized into a specific cellular compartment. The spatial determination mediated by the Arfrp1 helix requires its binding partner Sys1. In addition, the residues that are required for the acetylation of the Arfrp1 helix and the myristoylation of the Arl14 helix are important for the specific subcellular localization. Interestingly, Arfrp1 and Arl14 are recruited to their specific cellular compartments independent of GTP binding. Our results demonstrate that the amphipathic motifs of Arfrp1 and Arl14 are sufficient for determining specific subcellular localizations in a GTP-independent manner, suggesting that the membrane association and activation of some Arf proteins are uncoupled.

Martin Prescher
Dec 1, 2020; 61:1605-1616
Research Articles

Ying Zou
Dec 1, 2020; 61:1589-1604
Research Articles

ABCB4/MDR3 is located in the canalicular membrane of hepatocytes and translocates PC-lipids from the cytoplasmic to the extracellular leaflet. ABCB4 is an ATP-dependent transporter that reduces the harsh detergent effect of the bile salts by counteracting self-digestion. To do so, ABCB4 provides PC lipids for extraction into bile. PC lipids account for 40% of the entire pool of lipids in the canalicular membrane with an unknown distribution over both leaflets. Extracted PC lipids end up in so-called mixed micelles. Mixed micelles are composed of phospholipids, bile salts, and cholesterol. Ninety to ninety-five percent of the phospholipids are members of the PC family, but only a subset of mainly 16.0-18:1 PC and 16:0-18:2 PC variants are present. To elucidate whether ABCB4 is the key discriminator in this enrichment of specific PC lipids, we used in vitro studies to identify crucial determinants in substrate selection. We demonstrate that PC-lipid moieties alone are insufficient for stimulating ABCB4 ATPase activity, and that at least two acyl chains and the backbone itself are required for a productive interaction. The nature of the fatty acids, like length or saturation has a quantitative impact on the ATPase activity. Our data demonstrate a two-step enrichment and protective function of ABCB4 to mitigate the harsh detergent effect of the bile salts, because ABCB4 can translocate more than just the PC-lipid variants found in bile.

Beiging of white adipose tissue (WAT) has beneficial effects on metabolism. Although it is known that beige adipocytes are active in lipid catabolism and thermogenesis, how they are regulated deserves more explorations. In this study, we demonstrate that stearoyl-CoA desaturase 1 (SCD1) in subcutaneous WAT (scWAT) responded to cold stimulation and was able to promote mobilization of triacylglycerol [TAG (triglyceride)]. In vitro studies showed that SCD1 promoted lipolysis in C3H10T1/2 white adipocytes. The lipolytic effect was contributed by one of SCD1’s products, oleic acid (OA). OA upregulated adipose TAG lipase and hormone-sensitive lipase expression. When SCD1 was overexpressed in the scWAT of mice, lipolysis was enhanced, and oxygen consumption and heat generation were increased. These effects were also demonstrated by the SCD1 knockdown experiments in mice. In conclusion, our study suggests that SCD1, known as an enzyme for lipid synthesis, plays a role in upregulating lipid mobilization through its desaturation product, OA.

The battle for truth: The BBC's role at 100 22 November 2022 — 6:30PM TO 7:30PM Anonymous (not verified) 13 October 2022 Chatham House and Online

Tim Davie, director general of the BBC, and others discuss how the BBC shapes, and is shaped by, the world today.

This year, the BBC turns 100 and the World Service 90 in a world facing crises of increasing scale and frequency and in an age of disinformation, democratic disruption and a growing assault on truth and free reporting worldwide. What does this mean for Britain’s foremost news provider at home and across the globe?

This conversation considers:

• How does the BBC navigate a drastically changing media landscape?

• What does the BBC represent in the UK and to the world?

• What ‘soft power’ does the BBC have and how does it use it best?

As with all members events, questions from the audience drive the conversation.

Read the transcript. 

AMERICUS, Ga. — Georgia Southwestern State University graduate guard Destiny Garrett was named the Peach Belt Conference Women's Basketball Player of the Week this afternoon by the league office. Garrett set a school record with 13 assists in the 17th-ranked Lady Hurricanes 85-61 win over Florida Tech on Saturday and completed her first-ever double-double with a career-best 21 points. Garrett ...

The only daily TV news package to focus on Nova Scotians and their stories

The only daily TV news package to focus on Nova Scotians and their stories

CBC News reporter Sarah Law reports from Duluth, Minn., early Wednesday after Donald Trump defeated Kamala Harris to secure his second term as U.S. president.

Our community. Our neighbourhoods. The news of our city.

Make The Season Kind is a month of giving in support of The Food Bank of Waterloo Region. Join CBC K-W for a kick-off show on Friday, Dec. 6 at TheMuseum in downtown Kitchener with performances by I, The Mountain, singer-songwriter Mandippal, local chef Terry Salmond and more.

Pneumatic product manufacturer sees more than 80 percent increase in 3D model downloads in first two months

Minister of Communications and Digital Technologies Solly Malatsi has said his department will look into scrapping luxury tax on smartphones.

Some of Pakistan cricket's legends have criticised the Indian team's refusal to travel across the border for ICC Champions Trophy next year.

Team India is set to feature in an intra-squad warm-up game, starting Friday. But, fans won't be able to see the players in action.

OFFICE OF MANAGEMENT AND BUDGET: Division Of Facilities Management

Your sweet tooth could depend on your ability to digest sugar  BBC Science FocusView Full coverage on Google News

1. Nasa Alert: Massive 'God of Chaos' asteroid Apophis nears earth in closest pass yet  CNBCTV18
2. NASA alert! 'God of Chaos' asteroid approaching Earth on November 13 sparks worldwide concern  The Times of India
3. Giant Meteorite To Hit Earth On November 13? What We Know  News18
4. 'Astonishingly close': A colossal space rock could wreak havoc on Earth in 2029  Business Today
5. Giant 'God of Darkness' Asteroid May Not Escape Earth Unscathed  ScienceAlert

1. Delhi: India's capital chokes as air pollution turns 'severe'  BBC.com
2. Several flights diverted due to low visibility conditions at Delhi airport  The Times of India
3. Delhi's toxic air: Why you should not take your cough lightly  India Today
4. Delhi air pollution: Visibility near-zero amid thick smog; CPCB says AQI 'very poor', IQAir shows 'hazardous' | Details  Hindustan Times
5. Delhi's IGI airport sees flight diversions as season's first dense fog hits national capital  Moneycontrol

[COSATU] The Congress of South African Trade Unions (COSATU) is deeply concerned by the Minister for Communications and Digital Technologies, Mr. S. Malatsi's sudden withdrawal of the South African Broadcasting Corporation (SABC) SOC Ltd Bill from Parliament where it was being engaged upon by the National Assembly's Portfolio Committee: Communications and Digital Technologies.

Hi All,

I'm using a code (abConvertPolygonToPath.ils) that I found in other posts to convert a rect object to a path object inside a pcell code, but when I try to run a DRC, the layout export fails due to a warning message, here is the log message

*WARNING* (DB-270001): Pcell evaluation for 18A_asaavedr/lay_mesh_BM0_BM4_3p6_3p6/layout has the following error(s):

*WARNING* (DB-270002): ("eval" 0 t nil ("*Error* eval: undefined function" abConvertPolygonToPath))

ERROR (XOASIS-231): Pcell evaluation failed for '18A_asaavedr/lay_mesh_BM0_BM4_3p6_3p6/layout' because the Pcell SKILL code contains either a syntax error or an unsupported XOasis function. Check the standard output or the Virtuoso log file for more information. Cadence recommends correcting the Pcell SKILL code to resolve the issue. However, to ignore these errors and continue the translation, you may use the 'ignorePcellEvalFail' option.

INFO (XOASIS-282): Translation Failed. '1' error(s) and '3' warning(s) found.

And when compile the code I get the following message:

*WARNING* defgeneric function already defined - abConvertPolygonToPath

I will aprreciate any help in how to waive this error, or fix it.

Thank you

Dear all, 

I'm trying to perform an LVS check using Calibre between a layout that was generated by Innovus and the initial netlist generated by Genus. However, once I hit Run LVS on Calibre, it reports the following warnings and recommends to stop the process:

Source netlist references but does not define more than 10 subckts:
DFD1BWP7T
DFKCND1BWP7T
DFKCNQD1BWP7T
DFKSND1BWP7T
DFQD1BWP7T
IND2D0BWP7T
INR2D0BWP7T
INVD0BWP7T
INVD2P5BWP7T
IOA21D0BWP7T
... (and more)

If I proceed the LVS process it shows lots of errors as shown in the following image:

Why Genus doesn't include the definition of those sub circuits in the generated netlist? Is this related to Flat/Hierarchy netlisting? 

I have included my Genus scripts as well as the generated netlist in the attachments (and here - if attachment don't work).

Many thanks,

Anas