Researchers at Johns Hopkins University said Thursday work was ongoing at North Korean nuclear and missile sites, but no imminent threat is apparent.

World Password Day advice, GoDaddy hosting accounts hacked and WordPress sites under attack. Welcome to Cyber Security Today. It’s Wednesday May 6th. I’m Howard Solomon, contributing reporter on cybersecurity for ITWorldCanada.com. Tomorrow is World Password Day. So follow safe password practices so you don’t help criminals steal data. How bad are you? Here’s are few…

Clear Blue Technologies receives $3.5 million CAD deal to build out solar-powered cell networks in the Congo, Ghana, and Nigeria

A long-standing mystery of how a protein displayed on the surface of malaria parasites called "TRAP" interacts with human host cells has now been found.

With people looking to reduce monthly outgoings during the lockdown, one cut back is to declare a car as SORN to avoid tax and insurance costs - however, drivers are being urged not to pay to do so.

More than 86,000 people worldwide have been infected with the novel coronavirus and the global death toll is nearing 3,000.To try to prevent the spread of the virus, local governments have been closing tourist attractions that normally draw large crowds. World-famous destinations such as the Great Wall of China and the Venetian canals resemble ghost towns.As new coronavirus cases are confirmed daily, more closures and cancellations are expected. For the most up-to-date information on the status of an attraction or event, check the institution's or event's main web page.

London soil pollution worst on former Blitz bomb sites  Chemistry World

Malaria is a devastating disease caused by a protozoan parasite. It affects over 300 million individuals and results in over 400 000 deaths annually, most of whom are young children under the age of five. Hexokinase, the first enzyme in glucose metabolism, plays an important role in the infection process and represents a promising target for therapeutic intervention. Here, cryo-EM structures of two conformational states of Plasmodium vivax hexokinase (PvHK) are reported at resolutions of ∼3 Å. It is shown that unlike other known hexokinase structures, PvHK displays a unique tetrameric organization (∼220 kDa) that can exist in either open or closed quaternary conformational states. Despite the resemblance of the active site of PvHK to its mammalian counterparts, this tetrameric organization is distinct from that of human hexokinases, providing a foundation for the structure-guided design of parasite-selective antimalarial drugs.

Should global warming cause sea levels to rise as predicted in coming decades, thousands of archaeological sites in coastal areas around the world will be lost to erosion. With no hope of saving all of these sites, three archaeologists—Leslie Reeder of Southern Methodist University, Jon Erlandson of the University of Oregon and Torben Rick from the Smithsonian's National Museum of Natural History—have issued a call to action for scientists to assess the sites most at risk around the world.

The post Scientists issue call to action for archaeological sites threatened by rising seas, urban development appeared first on Smithsonian Insider.

Have you ever had a pet that seemed just a little bit crazy or odd? Can you be sure that it was in control of […]

The post Crazy eyes and mind control – the power of parasites appeared first on Smithsonian Insider.

Osiris Martinez-Guzman, Mathilda M. Willoughby, Arushi Saini, Jonathan V. Dietz, Iryna Bohovych, Amy E. Medlock, Oleh Khalimonchuk, and Amit R. Reddi

Heme is a cofactor and signaling molecule that is essential for much of aerobic life. All heme-dependent processes in eukaryotes require that heme is trafficked from its site of synthesis in the mitochondria to hemoproteins located throughout the cell. However, the mechanisms governing the mobilization of heme out of the mitochondria, and the spatio-temporal dynamics of these processes, are poorly understood. Herein, using genetically encoded fluorescent heme sensors, we developed a live cell assay to monitor heme distribution dynamics between the mitochondrial inner-membrane, where heme is synthesized, and the mitochondrial matrix, cytosol, and nucleus. Surprisingly, heme trafficking to the nucleus is ~25% faster than to the cytosol or mitochondrial matrix, which are nearly identical, potentially supporting a role for heme as a mitochondrial-nuclear retrograde signal. Moreover, we discovered that the heme synthetic enzyme, 5-aminolevulinic acid synthase (ALAS), and GTPases in control of the mitochondrial dynamics machinery, Mgm1 and Dnm1, and ER contact sites, Gem1, regulate the flow of heme between the mitochondria and nucleus. Overall, our results indicate that there are parallel pathways for the distribution of bioavailable heme.

Mark Torchin, a marine ecologist at the Smithsonian Tropical Research Institute (STRI) in Panama, talks about how he studies the parasites of invasive marine animals such as snails. Much of his research focuses on biological invasions and the dynamics between the host, the parasites and the surrounding ecosystem.

The post Meet our Scientist–Mark Torchin tracks invasive marine species and their parasites in Panama appeared first on Smithsonian Insider.

Zebra mussels in the Great Lakes, lionfish in the Atlantic and pythons in the Everglades: Large creatures like these generally draw the spotlight when talking […]

The post DNA is trusty new weapon for detecting slime nets and other invasive marine parasites appeared first on Smithsonian Insider.

The Earth’s changing climate could cause the extinction of up to a third of its parasite species by 2070, according to a global analysis reported […]

The post Study shows parasites may be among earliest victims of climate change appeared first on Smithsonian Insider.

In an August 18 letter, the U.S. Department of the Interior’s Office of Surface Mining Reclamation and Enforcement informed the National Academies of Sciences, Engineering, and Medicine that it should cease all work on a study of the potential health risks for people living near surface coal mine sites in Central Appalachia.

A new report from the National Academies of Sciences, Engineering, and Medicine recommends changes in the way that the U.S. Department of Energy manages science and technology (S&T) development in order to accelerate the cleanup of radioactive waste and contaminated soil, groundwater, and facilities at U.S. nuclear weapons sites.

An unknown threat actor is exploiting vulnerabilities in plugins for which patches have been available for months, or even years

The post Almost a million WordPress websites targeted in massive campaign appeared first on WeLiveSecurity

Researchers in Berlin have demonstrated that urban wasteland areas can be used as suitable habitats for a range of grassland species. Using simple and cost-effective measures to sow grassland seed mixtures, they found that such areas flourished despite poor soil conditions and high levels of impact from people.

Researchers in Berlin have demonstrated that urban wasteland areas can be used as suitable habitats for a range of grassland species. Using simple and cost-effective measures to sow grassland seed mixtures, they found that such areas flourished despite poor soil conditions and high levels of impact from people.

Researchers have proposed a new indexing scheme to help decision-makers prioritise brownfield sites for redevelopment. The scheme scores potential sites according to socio-economic, smart growth and environmental dimensions. By giving users the flexibility to emphasise some aspects of development as more important than others, it can be adapted for use in different contexts.

Better methods are needed to monitor underwater gas leaks. A new study outlines a technique that uses sound to detect bubbles of escaped gas and could help produce more accurate measurements of gas leakage rates from carbon capture and storage (CCS) sites, pipelines and natural leakage sites.

Aeration technologies designed to help landfill waste break down faster need to be refined in order to reduce pollution, greenhouse gas emissions and the long-term costs associated with landfill. This is according to a recent review of landfill aeration, which outlines some of the different systems currently available and highlights the need for better monitoring and sharing of data.

To restore a river site to good ecological status involves comparing it to similar sites that have been far less affected by human activity. A recent study has established a set of guidelines that define an acceptable level of human pressure that can be used to identify these minimally disturbed sites and ensure consistent ecological assessment among EU Member States.

A recent study has developed a mapping system to show the impact on habitats and species caused by construction projects, such as dams, near Natura 2000 conservation areas. Using a Greek case study, the system was able to identify risks from a dam construction project to species including otters, toads and tortoises.

New research suggests that Natura 2000 sites are highly effective in minimising the number of endangered species of concern to European conservation. The findings may reduce concerns that poor coordination between Member States in setting up the European network of protected areas has led to inadequate protection of vulnerable species.

Connectivity between protected areas is vital for safeguarding many animals and plants. New research has shown that Natura 2000 sites are well connected across provincial borders in Germany, Italy and Spain. This is the result of strong coordination from central governments combined with good regional cooperation, the study???s authors conclude.

Offshore renewable energy sites may provide new 'stepping stone' habitats for marine species, a recent study suggests. They could allow some species to spread beyond their present range and help vulnerable creatures survive in the face of climate change. However, they may also allow harmful invasive species to spread, the researchers warn, and the effects of such projects must be assessed by examining their impacts on the ecosystem as a whole.

A new decision-making aid to identify the best type of management plan for Natura 2000 sites has been developed by researchers. Using extensive data on different facets of biodiversity and human impacts, the researchers created two indices to show where conservation measures need to be integrated with socio-economic development. This study used sites in Italy as a case study but the method is widely applicable to all Natura 2000 sites, the researchers stress.

A new method for identifying forest sites to protect under the Natura 2000 network — as well as reviewing existing sites — is presented in a recent study. The modelling approach predicts the location of certain types of high nature value habitats using existing data on the distribution of key indicator species. The study demonstrates the method using the case of a German federal state, Lower Saxony.

Natura 2000 sites have, on average, 10% more carbon in their topsoil than non-protected areas, according to new research. They also generally have lower economic value for agriculture. The results suggest that there is significant potential to develop win-win biodiversity conservation and climate change mitigation efforts within the EU.

A species of mussel has been used to investigate the connectivity of two marine protected areas (MPAs) along the central Portuguese west coast in a new study. The chemistry of mussel shells was used to trace the dispersal routes for larval mussels, demonstrating that the Arrábida MPA is an important source population in the area.

A recent study has analysed the physical and chemical characteristics of particulate matter (PM) from 60 sites across Europe. The results suggest there is no single ratio between PM_2.5 and PM₁₀ mass concentrations for all the sites, and that PM mass cannot be directly related to the concentration of particle numbers.

A fast and reliable method to measure the environmental impact of landfill sites has been developed by researchers. Analysis of the chemical composition of gas emissions and water leaching from sites provides a detailed picture of the extent of environmental pollution around landfill sites. Such monitoring is essential in order to manage risks to human health and natural resources.

Mercury levels in bream (Abramis brama) collected from six European sampling sites from 2007 to 2013 exceeded the Water Framework Directive’s safety limit for fish in all but one site in 2012, a new study discovers. The findings suggest greater efforts need to be made to prevent mercury pollution.

Fuel spillages and leaks from petroleum storage facilities can lead to serious pollution of soils and underground water. In a recent study, two strains of Rhodococcus bacteria were found to be effective at degrading a number of petroleum hydrocarbons and thus helping clean up contaminated sites.