Insights were obtained into the structure of the 4-hydroxy-tetrahydrodipicolinate synthase from the thermoacidophilic methanotroph Methylacidiphilum fumariolicum SolV and the phylogeny of the aminotransferase pathway for the biosynthesis of lysine.

It’s not an exaggeration to say Hedrick was ecstatic when she peered into her inverted phase contrast microscope and found "Amphisolenia quadrispina" floating in her sample. “For 20 years I’ve been hoping to see something like this,” she says.

The post From the Bay of Bengal, a dinoflagellate makes its way to the Smithsonian appeared first on Smithsonian Insider.

Birds do it. Bees do it. And in a laboratory in northern California, scientists using bumblebees recently figured out the best way to measure it--vertical lift!

The post Laboratory tests reveal precise way to measure vertical lift in bumblebees and other small insects and birds appeared first on Smithsonian Insider.

A new computer simulation by Gurtina Besla of the Harvard-Smithsonian Center for Astrophysics and her colleagues now shows that the Magellanic Stream resulted from a past close encounter between two dwarf galaxies rather than effects of the Milky Way.

The post Milky Way sidelined in galactic tug of war appeared first on Smithsonian Insider.

For two weeks the team recorded and documented the community’s elders, families and llamas along a pilgrimage of remembrance in Pisaq, Peru.

The post American Indian Museum launches Chawaytiri documentation project in Peru appeared first on Smithsonian Insider.

Recent work has added dozens of new measurements to star-forming regions in the Milky Way. These measurements have changed the map of the Milky Way, indicating our galaxy has four spiral arms, not two, as previously thought.

The post Very Large Baseline Array telescope is helping Smithsonian astronomers remap Milky Way and Andromeda galaxies appeared first on Smithsonian Insider.

Smithsonian Secretary Wayne Clough, left, talks with Carlos Jaramillo, scientist at the Smithsonian Tropical Research Institute in Panama, at a research site near the Panama […]

The post Wayne Clough & Carlos Jaramillo, at a research site near the Panama Canal. appeared first on Smithsonian Insider.

To celebrate leap day, here are some fun facts about frog leaping.

The post Leap Day the Frog Way appeared first on Smithsonian Insider.

Seven years ago, astronomers boggled when they found the first runaway star flying out of our Galaxy at a speed of 1.5 million miles per hour. Theorists wondered: Could the same thing happen to planets? New research shows that the answer is yes.

The post Planet starship: runaway planets zoom at a fraction of light speed appeared first on Smithsonian Insider.

An international team of scientists has discovered an ‘ordinary’ black hole in the galaxy Centaurus A. This is the first time that a normal-size black hole has been detected away from the immediate vicinity of our own Galaxy.

The post “Ordinary” black hole discovered in a galaxy 12-million-light-years away appeared first on Smithsonian Insider.

The newfound jets may be related to mysterious gamma-ray bubbles that Fermi detected in 2010. Those bubbles also stretch 27,000 light-years from the center of the Milky Way.

The post Ghostly gamma-ray beams blast from Milky Way’s center appeared first on Smithsonian Insider.

Their research revealed that the types of waterbirds that inhabit urban estuaries are influenced not only by urban development, but also by a far more natural process―rain.

The post Scientists find that rain may not always be a welcome thing to waterbirds appeared first on Smithsonian Insider.

stronomers have used NASA's Chandra X-ray Observatory to find evidence our Milky Way Galaxy is embedded in an enormous halo of hot gas that extends for hundreds of thousands of light years.

The post Chandra X-ray Observatory shows Milky Way is surrounded by halo of hot gas appeared first on Smithsonian Insider.

One of the closest galaxies to the Milky Way almost got away with theft....

The post Galactic thief: “I would have gotten away with it but for those meddling astronomers!” appeared first on Smithsonian Insider.

Astronomers have identified a new structure in the Milky Way: a long tendril of dust and gas that they are calling a "bone."

The post First “bone” of the Milky Way identified appeared first on Smithsonian Insider.

The uplift of the Isthmus of Panama 2.6 million years ago formed a land-bridge that has long thought to be the crucial step in the […]

The post Alligator relatives crossed ancient seaway appeared first on Smithsonian Insider.

The center of the Milky Way galaxy, with The supermassive black hole Sagittarius A–at center–is revealed in this image. Astronomers have used NASA’s Chandra X-ray Observatory to […]

The post Sagittarius A: Center of the Milky Way appeared first on Smithsonian Insider.

Chip a tooth and expose a nerve and the result can be a searing sensitivity to hot and cold. The hard outer layer of a […]

The post Scientists map pathway from narwhals’ sensitive tusk to brain appeared first on Smithsonian Insider.

Here at Smithsonian Science we are celebrating Sloth Week with four little-known facts about sloths, some of which we found in the Smithsonian’s very own […]

The post Discover sloths in a whole new way! appeared first on Smithsonian Insider.

When astronomers study protoplanetary disks of gas and dust that surround young stars, they sometimes spot a dark gap like the Cassini division in Saturn’s […]

The post Disk Gaps Don’t Always Signal Planets appeared first on Smithsonian Insider.

Now here is something to ruminate on. About 85 percent of the methane produced by a cow comes out of its mouth as burps. The […]

The post Monitoring methane? Now there is a better way to measure appeared first on Smithsonian Insider.

Most people think of black holes as giant vacuum cleaners sucking in everything that gets too close. But the supermassive black holes at the centers […]

The post Event Horizon Telescope Reveals Magnetic Fields at Milky Way’s Central Black Hole appeared first on Smithsonian Insider.

In April 2015, after traveling for about half the age of the universe, a flood of powerful gamma rays from a distant galaxy slammed into […]

The post VERITAS Detects Gamma Rays from Galaxy Halfway Across the Visible Universe appeared first on Smithsonian Insider.

The center of the Milky Way galaxy is currently a quiet place where a supermassive black hole slumbers, only occasionally slurping small sips of hydrogen […]

The post The Milky Way’s blowout bash 6 million years ago! appeared first on Smithsonian Insider.

The 11 farthest known stars in our galaxy are located about 300,000 light-years from Earth, well outside the Milky Way’s spiral disk. New research by […]

The post Farthest Milky Way stars might be ripped from another galaxy appeared first on Smithsonian Insider.

Plastic debris floating in the ocean has become a powerful new passport to far-away destinations for a wide variety of invasive species, according to new […]

The post Tsunami reveals drifting ocean plastic opens globe to invasive castaways appeared first on Smithsonian Insider.

Smithsonian scientists have joined NASA and other organizations this summer to do something incredible: launch a spacecraft, the Parker Solar Probe, into space and have […]

The post A solar probe is on its way to touch the sun. The Smithsonian built the tool that will measure the sun without melting appeared first on Smithsonian Insider.

Stephen Kershaw, David J. Morgan, James Boyd, David G. Spiller, Gareth Kitchen, Egor Zindy, Mudassar Iqbal, Magnus Rattray, Chris M. Sanderson, Andrew Brass, Claus Jorgensen, Tracy Hussell, Laura C. Matthews, and David W. Ray

Glucocorticoids (GCs) act through the glucocorticoid receptor (GR) to regulate immunity, energy metabolism, and tissue repair. Upon ligand binding, activated GR mediates cellular effects by regulating gene expression, but some GR effects can occur rapidly without new transcription. We show GCs rapidly inhibit cell migration, in response to both GR agonist and antagonist ligand binding. The inhibitory effect on migration is prevented by GR knockdown with siRNA, confirming GR specificity, but not by actinomycin D treatment, suggesting a non-transcriptional mechanism. We identified a rapid onset increase in microtubule polymerisation following glucocorticoid treatment, identifying cytoskeletal stabilisation as the likely mechanism of action. HDAC6 overexpression, but not knockdown of αTAT1, rescued the GC effect, implicating HDAC6 as the GR effector. Consistent with this hypothesis, ligand-dependent cytoplasmic interaction between GR and HDAC6 was demonstrated by quantitative imaging. Taken together, we propose that activated GR inhibits HDAC6 function and thereby increases the stability of the microtubule network to reduce cell motility. We therefore report a novel, non-transcriptional mechanism whereby GCs impair cell motility through inhibition of HDAC6 and rapid reorganization of the cell architecture.

Inupiaq artist and teacher Holly Nordlum visited the National Museum of the American Indian to study Arctic objects and archival photographs in the museum’s collections. […]

The post Art to Help Boys Find Their Way appeared first on Smithsonian Insider.

New on Smithsonian Folkways Recordings: This official music video is for “Ripest of Apples” by Anna & Elizabeth, from the new album ‘The Invisible Comes […]

The post Smithsonian Folkways new release appeared first on Smithsonian Insider.

Businesses are cutting back on hours to avoid having to provide health care coverage under the new Affordable Care Act.

Steve Julian: Business analyst Mark Lacter, who's affected here?

Mark Lacter: Thirty hours a week is the magic number for workers to be considered full time under the new law.  If a business has 50 or more full-time employees, health care coverage has to be provided.  Except that a lot business owners say that the additional cost is going to be a financial killer, so instead, some of them have been cutting back hours to below that 30-hour threshold.  More than 200,000 Californians are at risk of losing hours from the health care law - that according to one study.

Julian: What kinds of businesses are doing this?

Lacter: Restaurant chains have received much of the attention, but the city of Long Beach, as an example, is going to reduce hours for a couple of hundred of its workers.  And, last week came word that the L.A.-based clothing chain Forever 21 will cut some of its full-time employees to a maximum 29-and-a-half hours a week, and classify them as part time.  That touched off an outcry on the Internet - people were saying that Forever 21 was being unfair and greedy - though the company says that only a small number of employees are affected, and that its decision has nothing to do with the Affordable Care Act.  There's really no way to know - Forever 21 is a private company, which means it's not obligated to disclose a whole lot.  What we do know is that those people will be losing their health care coverage.

Julian: And, the ultimate impact on businesses and workers?

Lacter: Steve, you're looking at several years before the picture becomes clear.  Here in California, workers not eligible for health care through their employer can get their own individual coverage, and if their income levels are not over a certain amount, they'd be eligible for Medicaid.  And, let's not forget many businesses already provide coverage for their employees.  So, lots of rhetoric - but, not many conclusions to draw from, which does make you wonder why so many business owners are unwilling to at least give this thing a chance.  Just doesn't seem to be much generosity of spirit for their workers, not to mention any recognition that if people can go to a doctor instead of an emergency room we'd probably all be better off.

Julian: Health care is far from the only controversy for Forever 21, true?

Lacter: In some ways, it's one of the biggest Southern California success stories.  Don Chang emigrated here in 1981 from Korea at the age of 18, opened his first store in Highland Park three years later (it was called Fashion 21), and he never looked back.  Today, revenues are approaching $4 billion.  But, the guy must have some pretty hefty legal bills because his company has been accused of all kinds of workplace violations.  The lawsuits alleged that workers preparing items for the Forever 21 stores didn't receive overtime, that they didn't get required work breaks, that they received substandard wages, and that they worked in dirty and unsafe conditions - sweatshop conditions, essentially.

Julian: Are most of their claims settled out of court?  You don't hear much about them.

Lacter: They are, which means there's usually a minimal amount of media coverage.  If a privately held company decides to keep quiet by not releasing financial results or other operational information, there's not likely to be much of a story - unlike what happens with a company like Apple, which is always under scrutiny.  Sometimes, plaintiffs will try to organize class-action suits, but that's extremely tough when you're dealing with low-wage workers who are often very reluctant to get involved because of their legal status.  And, let's not forget that Forever 21 - like any low-cost retailer - is simply catering to the demand for cheap, stylish clothes that are made as quickly as possible.

Julian: I guess you can't make that happen when wages and benefits are appreciably higher than your competition.

Lacter: The next time you walk into a Forever 21 store and wonder how prices can be so reasonable, that's how.

Mark Lacter writes for Los Angeles Magazine and pens the business blog at LA Observed.com.

This content is from Southern California Public Radio. View the original story at SCPR.org.

Yesterday may have been a holiday on paper, but if you were navigating LA's major freeways, there was no sign people had the day off.

Steve Julian: Business analyst Mark Lacter, is this more evidence that Southern California traffic getting worse?

Mark Lacter: Steve, L.A. continues to be the most clogged-up city in the U.S. - according to something called the TomTom Traffic Index - with commuters caught up in delays, on average, 35 percent of the time.  Or, to put it another way, L.A. commuters are in congestion up to 40 minutes of each hour they're driving.  The worst time of the week to commute is Thursday night; that's when there's congestion more than 80 percent of the time.  Monday morning commutes are the lightest.

Julian: After L.A., where should you not live if congestion bugs you?

Lacter: The next worst cities in the U.S. are San Francisco, Honolulu, Seattle, and San Jose.  Now, the Census Bureau comes up with its own commuting surveys, and if you compare the most recent numbers with those back in 2000, you'll see that things aren't all that different.  Matter of fact, the percentage of commuters driving alone to work actually increased a little over the last decade to 72 percent, while the percentage of those carpooling has declined.

Julian: What about public transit?

Lacter: Well, the numbers are up slightly from 2000, but only to 7.3 percent of all commuters.  So, even assuming that the number inches up in the next couple of years when the Expo Line extends into Santa Monica, it's still a smallish piece of the pie.  And, since many of the other public transit projects being planned are decades away from being completed, those numbers might not change much.  One other thing, Steve: less than 1 percent of all L.A. commuters bike to work, which would throw cold water on the idea that biking in L.A. is becoming a popular way of getting to the office.

Julian: People just prefer commuting by car…

Lacter: It remains the most convenient way of getting around - despite the congestion.  New car sales are up 14 percent through the first nine months of the year in Southern California.  Add to that are generally affordable gas prices (they've been especially low in the last few weeks).  In other parts of the world, congestion is considered a good thing because it means that the economy is doing well.  Which explains that while L.A. is the most congested city in the U.S., it doesn't rank among the 10 around the world.  On that front, Moscow is tops, followed by Istanbul, and Rio de Janeiro.

Julian: What about driverless cars?

Lacter: Well, these vehicles hold the most promise for reducing accidents, lowering travel times, and improving fuel economy - and you don't have to give up your car.  Actually, a lot of the technology is already in place - that includes stuff like radar-based cruise control, and devices that keep you at a safe distance from the car in front of you.  The trick, of course, is taking these individual capabilities and integrating them into an entirely driverless car.  Several car companies say they could be ready to start selling by 2020, with Google saying that its car could be ready even sooner.

Julian: Is that realistic?

Lacter: Who knows?  But even if the dates can be met - and that's a big if, considering how complex these systems are - legislatures will have to determine, among other things, whether vehicles can be fully autonomous (meaning that you can curl up and take a nap while the computer is driving by itself).  Or, whether they will only be semi-autonomous, which would be like an airline crew using automatic pilot, but always prepared to take over the controls.

Julian: Is that a liability issue?

Lacter: Yes - if something does go wrong, who will get the blame?  The owner of the vehicle?  The carmaker?  The suppliers of the car companies?  These questions might take years to get resolved in the courts - and even then, it could be years before the percentage of these vehicles on the road is large enough to truly have an impact.  But, considering that most commuters aren't willing to give up their cars, this would seem to be the most exciting, most desirable idea.  One day.

Mark Lacter writes for Los Angeles Magazine and pens the business blog at LA Observed.com.

This content is from Southern California Public Radio. View the original story at SCPR.org.

Plants are among the world’s best carbon sinks, but there’s a side to the plant-CO2 love affair that’s rarely discussed. When carbon dioxide rises, plants […]

The post The strange, controversial way plants trap CO2 appeared first on Smithsonian Insider.

Camouflage is a valuable survival strategy—just ask a chameleon. Scientists have just discovered a new form of mimicry camouflage: beetles that hide by chewing beetle-shaped […]

The post For millions of years these tiny beetles have chewed their way out of sight appeared first on Smithsonian Insider.

File: A general view during player introductions before game one of the National League Division Series between the Los Angeles Dodgers and the New York Mets at Dodger Stadium on Oct. 9, 2015 in Los Angeles.; Credit: Stephen Dunn/Getty Images

Do you want to track the Dodgers as the new season gets underway, but either don't have cable or are at work during the game? Maybe you want to keep an eye on the boys in blue but have an office job that gives you checks in black and white, and you want to keep your bleeding red for your favorite team from sending your bank account into the red as well. Or maybe you just aren’t going to have access to a TV at the time. Here are four ways to check the Dodgers out this season.

1. Track what’s happening with MLB.com’s free Gameday service

Want to see what’s going on as if the Dodgers game was a video game? You have to pay if you want to watch video (with alternate angles!) or listen to audio with Major League Baseball's MLB.tv service — but you can watch virtual avatars simulating the game with MLB Gameday for free. Just visit MLB.com/scores, then click on the Gameday button beneath the game you want to follow. Or, you can keep it more old school by tracking scores on the scores page — alongside video highlights.

2. Follow what’s going on on Twitter

Want to keep an eye on things but don’t want to stare at a streaming video feed? You can follow what’s happening with Twitter. The Dodgers themselves tweet highlights and results at @Dodgers, plus you can do a search for “Dodgers” or track what’s happening on various popular hashtags, including #Dodgers, #ThinkBlue and #ITFDB (It’s Time For Dodgers Baseball).

3. Listen to the radio, over the air or online

The official Dodgers radio broadcaster in L.A. is AM 570 L.A. Sports. As noted above, you can also pay to listen to audio from MLB.tv — but the service isn't available for local, "in-market" games, which are blacked out as part of their contracts with local broadcasters. The Dodgers broadcasts are also available in Spanish on 1020 AM KTNQ.

4. Stream ESPN on your computer, phone or tablet

ESPN lets you watch the opening day game and others throughout the season online... well, some of you, at least. Due to various cable company deals and other red tape, you have to already be a cable subscriber — sorry, cord cutters — but most major cable company subscribers can log in and stream the Dodgers online, or using ESPN's mobile apps available on iOS and Android. That also means you can find a friend who has cable, and team up with them to watch online — or just hang out at their place for the foreseeable future.

Many other Dodgers games throughout the season will be on SportsNet L.A., but you have to subscribe to Charter Spectrum, Time Warner, or Bright House in the L.A. area to get this channel. However, five of the games this season will be shown on KTLA, expanding your options for potentially checking the Dodgers out. You can find out more in the SportsNet L.A. FAQ.

How are you tracking the Dodgers? Let us know in the comments or by tweeting us at @KPCC.

This story has been updated; it was originally published in 2013.

This content is from Southern California Public Radio. View the original story at SCPR.org.

Full Text:

Bridges make travel faster and more convenient, but, in an earthquake, these structures are subject to forces that can cause extensive damage and make them unsafe. Now civil and environmental engineer Petros Sideris of Texas A&M University is leading a National Science Foundation (NSF)-funded research project to investigate the performance of hybrid sliding-rocking (HSR) columns. HSR columns provide the same support as conventional bridge infrastructure columns but are more earthquake-resistant. HSR columns are a series of individual concrete segments held together by steel cables that allow for controlled sliding and rocking. This allows the columns to shift without damage, while post-tensioning strands ensure that at the end of an earthquake the columns are pushed back to their original position. Conventional bridges are cast-in-place monolithic concrete elements that are strong but inflexible. Structural damage in these bridge columns, typically caused by a natural disaster, often forces a bridge to close until repairs are completed. But bridges with HSR columns can withstand large earthquakes with minimal damage and require minor repairs, likely without bridge closures. Such infrastructure helps with post-disaster response and recovery and can save thousands in taxpayer dollars. In an earthquake, HSR columns provide "multiple advantages to the public," Sideris said. "By preventing bridge damage, we can maintain access to affected areas immediately after an event for response teams to be easily deployed, and help affected communities recover faster. In mitigating losses related to post-event bridge repairs and bridge closures, more funds can be potentially directed to supporting the recovery of the affected communities." According to Joy Pauschke, NSF program director for natural hazards engineering, "NSF invests in fundamental engineering research so that, in the future, the nation's infrastructure can be more resilient to earthquakes, hurricanes, and other forces of nature."

Image credit: Texas A&M University

A report released today by the National Research Council presents a new framework for K-12 science education that identifies the key scientific ideas and practices all students should learn by the end of high school.

As immigrants and their descendants become integrated into U.S. society, many aspects of their lives improve, including measurable outcomes such as educational attainment, occupational distribution, income, and language ability, but their well-being declines in the areas of health, crime, and family patterns, says a new report from the National Academies of Sciences, Engineering, and Medicine.

U.S. adults perform comparably to adults in other economically developed countries on most measures of science knowledge and support science in general, says a new report from the National Academies of Sciences, Engineering, and Medicine.

A new book from the National Academies of Sciences, Engineering, and Medicine outlines how educators can develop and adapt student assessments for the classroom that reflect the approach to learning and teaching science described in the Next Generation Science Standards (NGSS) and similar standards.

To enable public transit agencies to engage in more rigorous and effective safety planning, their safety planning records should not be admissible as evidence in civil litigation, says a new report from the National Academies of Sciences, Engineering, and Medicine.

Given the current state of quantum computing and the significant challenges that still need to be overcome, it is highly unlikely that a quantum computer that can compromise public-key cryptography – a basis for the security of most of today’s computers and networks – will be built within the next decade, says a new report by the National Academies of Sciences, Engineering, and Medicine.

The future of the U.S. Interstate Highway System is threatened by a persistent and growing backlog of structural and operational deficiencies and by various looming challenges, such as the progress of automated vehicles, developments in electric vehicles, and vulnerabilities due to climate change.