League Managers Association chief executive Richard Bevan has warned the Premier League season could be cancelled if clubs do not agree to playing at neutral grounds.
Welcome to the Evening Standard's LIVE coverage as the coronavirus crisis continues to heavily impact sport across the globe.
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Tel Aviv University (TAU) researchers have developed a safe and accurate 3D imaging method to identify sperm cells moving at a high speed. The new method has the potential to significantly improve IVF treatments.
A new study shows how stem cells -- which can contribute to creating many parts of the body, not just one organ or body part -- are able to postpone their own death in order to respond to an injury that needs their attention. The study was done in planarians, which are tiny worms used as model organisms to study regeneration because of their ability to recover from any injury using stem cells.
Hematopoietic stem cells from a healthy donor can help patients suffering from acute leukemia. However, the side effects of therapies are often severe. A group of researchers led by the University of Zurich have now shown how human healthy and cancerous hematopoietic stem cells can be more selectively eliminated using immunotherapy instead of chemotherapy in mice. The aim is to test the new immunotherapy in humans as soon as possible.
With a discovery that could rewrite the immunology textbooks, an international group of scientists, including the teams of Bart Lambrecht, Martin Guilliams, Hamida Hammad, and Charlotte Scott (all from the VIB-UGent Center for Inflammation Research) identified a new type of antigen-presenting immune cell.
Notting Hill Carnival has been cancelled for the first time ever because of the ongoing coronavirus crisis.
More than 6,000 people have complained to the ACCC about their travel company's handling of refunds. We've looked into what your options are for getting your money back.
The travel agent chain backs down from charging hundreds of dollars in cancellation fees for trips cancelled due to COVID-19 restrictions, following pressure from customers and the Australian Competition and Consumer Commission.
South Australia's Independent Commissioner Against Corruption confirms he is investigating allegations of improper conduct by the vice-chancellor of the University of Adelaide.
Aiming to enable a “nirvana” experience for travelers has driven CellPoint towards block-chain powered, biometric-enabled identification.
Keep on reading: Growth Players: CellPoint Mobile’s CEO Kristian Gjerding
Australia's toughest off-road motorsport event is called off for the first time in its 44-year history amid concerns competitors or visitors might spread coronavirus to remote communities.
Wimbledon will not take place for the first time in over 85 years, with The All England Club calling off The Championships for this year due to the coronavirus pandemic.
The sporting fallout from the coronavirus pandemic continues, with The Open cancelled and golf's three other majors rearranged.
Mental health advocate Malin Andersson reacted to the news that the ITV2 dating show has been shelved
Researchers at Purdue University have developed a new technique to dramatically enhance the resolution achievable when imaging intracellular structures with super-resolution fluorescence microscopy. The technique uses the distortions created by a specimen to pinpoint the location of individual molecules, and thereby infer the location of intracellular structures. The technique could be particularly useful in studying […]
Chimeric antigen receptor T-cell therapies have shown remarkable efficacy in leukemia and lymphoma patients who relapsed or were refractory to several prior treatments, but many challenges remain in the cancer cell therapy field. Strategies that may improve upon first-generation therapies were presented during the American Association for Cancer Research virtual meeting with encouraging early activity, […]
A Phase 3 study of Sanofi and Regeneron’s Libtayo (cemiplimab) as a monotherapy for advanced or metastatic non-small cell lung cancer (NSCLC) has been stopped early after showing strong overall survival benefit, it has emerged.
The FDA has awarded marketing authorisation to Novartis for the Oral MET inhibitor Tabrecta for the first-line treatment of metastatic non-small cell lung cancer in patients whose tumors have a mutation that leads to MET exon 14 skipping (METex14), regardless of whether they have previously received any type of treatment.
The submission of additional information, upon the request of the US regulator, has delayed the action…
Armando Gonzalez-Medina, 35, of Richmond, Va., was sentenced today to 84 months in prison, after pleading guilty to participating in a racketeering conspiracy and conspiring to possess, produce and transfer fraudulent identification documents.
A federal grand jury returned a two-count indictment today charging Samuel Stone, 32, with first degree murder and murder by a federal prisoner serving a life sentence.
The department said that this is the first time website domains involving cell phone app marketplaces have been seized.
It’s a pleasure to stand with you – and to help welcome so many colleagues and distinguished guests to the Great Hall – as we recognize the achievements, and celebrate the contributions, of the 39 accomplished LEAP graduates who make up our Class of 2013.
From : Communities>>Regulatory Open Forum
The short answer is "yes" provided that the development cell bank was the source for the GMP bank and is comparable in terms of performance. However, the devil is in details and you need to evaluate "comparability" carefully between the development bank and the GMP bank with respect to the characterization data you plan to use for, e.g., to support GMP bank for production, etc. Two ICH guidance documents are useful to look at, Q7 Table 1 and Q5D. The US FDA generally follows ICH guidance but EMA [More]
Objective responses seen in 29% of patients with locally advanced basal cell carcinoma (BCC)
Celltrion has submitted an application to the European Medicines Agency (EMA) for its adalimumab biosimilar, currently known as CT-P17.
The successful activation of T cells is critical to the immune system's ability to clear infections. A retrospective study in China found that COVID-19 patients had remarkably low T-cell counts in their blood, while some pro-inflammatory cytokines such as IL-6—which Roche’s Actemra targets—were elevated.
After penning a deal with Eli Lilly last month with the aim to have an antibody in the clinic within four months, Canadian-based AbCellera has been given a financial boost by its government.
U.S. and U.K. intel agencies are reviewing the private report, but intel analysts examined and couldn't confirm a similar theory previously.
Yokogawa Electric Corporation (TOKYO: 6841) announces that it has developed the SU10 Single Cellome Unit, a device that uses a nanopipette to inject substances such as genes and drugs and aspirate intracellular materials at target locations in individual cells.