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Premier League season could be cancelled if clubs do not agree to play at neutral grounds, warns LMA chief

League Managers Association chief executive Richard Bevan has warned the Premier League season could be cancelled if clubs do not agree to playing at neutral grounds.




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Coronavirus sport news LIVE: Fears Premier League season could be cancelled; Barcelona set return date

Welcome to the Evening Standard's LIVE coverage as the coronavirus crisis continues to heavily impact sport across the globe.




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PhoneQuake — Best Cell Phone Plans For Kids - If you are like...

Best Cell Phone Plans For Kids - If you are like most parents, you want your kids to be happy, and you want them to stay safe but giving your kid a cell phone may seem a little overzealous, a mobile device can be a terrific way to always be in touch…




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PhoneQuake — Best Cell Phone Plans For College Students - Being...

Best Cell Phone Plans For College Students - Being a student means making budget your middle name. What better place to start than with your cell phone plan? You want enough minutes, lots of texting, and a data plan that won’t quit. College is an ex…




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PhoneQuake — Page Plus Cell Phone Plans - Among prepaid cell...

Page Plus Cell Phone Plans - Among prepaid cell phone services, Page Plus is unique. It’s one of the few prepaid providers that operates on Verizon’s network. Verizon’s coverage is universally recognized as the strongest and most reliable in America…




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PhoneQuake — Project Fi Cell Phone Plans - Project Fi is one of...

Project Fi Cell Phone Plans - Project Fi is one of the few wireless carriers in the U.S. to refund you for the data you don’t use, meaning that if you churn through 3.5GB data in one month on a 4GB plan, you are credited the remaining 0.5GB. Fi’s ne…




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PhoneQuake — AARP Cell Phone Plans Discounts For Seniors - If...

AARP Cell Phone Plans Discounts For Seniors - If you are over fifty with an AARP membership, you qualify to enjoy a discount. AARP members can save money with a number of wireless service providers. AARP, formerly known as the American Association o…




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PhoneQuake — Best Prepaid Cell Phone Plans - For people who...

Best Prepaid Cell Phone Plans - For people who don’t like the idea of signing a long-term contract then choosing the best prepaid cell phone plans might fit your needs. A prepaid phone plan is the only way to control your monthly cell phone bill. Yo…

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PhoneQuake — Best Unlimited Data Plans - Do you use your cell...

Best Unlimited Data Plans - Do you use your cell phone for streaming music or videos or use it as a Wi-Fi hotspot? Having unlimited data could really save you some money on your next phone bill. Switching to an unlimited data plan would allow you to…




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Accurate 3D imaging of sperm cells moving at top speed could improve IVF treatments

Tel Aviv University (TAU) researchers have developed a safe and accurate 3D imaging method to identify sperm cells moving at a high speed. The new method has the potential to significantly improve IVF treatments.




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Stem cells shown to delay their own death to aid healing

A new study shows how stem cells -- which can contribute to creating many parts of the body, not just one organ or body part -- are able to postpone their own death in order to respond to an injury that needs their attention. The study was done in planarians, which are tiny worms used as model organisms to study regeneration because of their ability to recover from any injury using stem cells.




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More selective elimination of leukemia stem cells and blood stem cells

Hematopoietic stem cells from a healthy donor can help patients suffering from acute leukemia. However, the side effects of therapies are often severe. A group of researchers led by the University of Zurich have now shown how human healthy and cancerous hematopoietic stem cells can be more selectively eliminated using immunotherapy instead of chemotherapy in mice. The aim is to test the new immunotherapy in humans as soon as possible.




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Newly discovered cell type plays crucial role in immune response to respiratory infections

With a discovery that could rewrite the immunology textbooks, an international group of scientists, including the teams of Bart Lambrecht, Martin Guilliams, Hamida Hammad, and Charlotte Scott (all from the VIB-UGent Center for Inflammation Research) identified a new type of antigen-presenting immune cell.




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Notting Hill Carnival 2020: Event cancelled for the first time ever

Notting Hill Carnival has been cancelled for the first time ever because of the ongoing coronavirus crisis.




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'Unfair': Flight Centre draws fire over $300 charge for COVID cancellations

A Victorian family whose dream holiday to the US was cancelled because of coronavirus has accused Flight Centre of "robbery" for refusing to refund the full cost of a Disneyland pass.




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'Unfair': Flight Centre draws fire over $300 charge for COVID cancellations

A Victorian family whose dream holiday to the US was cancelled because of coronavirus has accused Flight Centre of "robbery" for refusing to refund the full cost of a Disneyland pass.




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Can't get a refund on your cancelled trip? Here's what to do

More than 6,000 people have complained to the ACCC about their travel company's handling of refunds. We've looked into what your options are for getting your money back.




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Flight Centre stops charging cancellation fees for trips affected by coronavirus

The travel agent chain backs down from charging hundreds of dollars in cancellation fees for trips cancelled due to COVID-19 restrictions, following pressure from customers and the Australian Competition and Consumer Commission.




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ICAC investigating alleged 'improper conduct' by university vice-chancellor

South Australia's Independent Commissioner Against Corruption confirms he is investigating allegations of improper conduct by the vice-chancellor of the University of Adelaide.




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'Unfair': Flight Centre draws fire over $300 charge for COVID cancellations

A Victorian family whose dream holiday to the US was cancelled because of coronavirus has accused Flight Centre of "robbery" for refusing to refund the full cost of a Disneyland pass.




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Tours cellulaires incendiées: un chanteur passera le week-end en prison

Il aurait incendié des tours de télécom avec sa blonde.




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Growth Players: CellPoint Mobile’s CEO Kristian Gjerding

Aiming to enable a “nirvana” experience for travelers has driven CellPoint towards block-chain powered, biometric-enabled identification.

Keep on reading: Growth Players: CellPoint Mobile’s CEO Kristian Gjerding




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Finke Desert Race cancelled due to coronavirus, costing Alice Springs millions

Australia's toughest off-road motorsport event is called off for the first time in its 44-year history amid concerns competitors or visitors might spread coronavirus to remote communities.




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Wimbledon cancelled for first time since World War II due to coronavirus pandemic

Wimbledon will not take place for the first time in over 85 years, with The All England Club calling off The Championships for this year due to the coronavirus pandemic.




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The Open cancelled as golf's other majors are rescheduled

The sporting fallout from the coronavirus pandemic continues, with The Open cancelled and golf's three other majors rearranged.




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Former Love Island contestant says she's 'glad' the show has been cancelled

Mental health advocate Malin Andersson reacted to the news that the ITV2 dating show has been shelved




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New Fluorescence Microscopy Technique for Nanostructure Visualization Within Cells

Researchers at Purdue University have developed a new technique to dramatically enhance the resolution achievable when imaging intracellular structures with super-resolution fluorescence microscopy. The technique uses the distortions created by a specimen to pinpoint the location of individual molecules, and thereby infer the location of intracellular structures. The technique could be particularly useful in studying […]




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Thumbs Up to Latest CAR T-Cell Approval

New era for lymphoma, leukemia, possibly other cancers




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Encouraging Signals for New Cancer Cell Therapy Strategies

Chimeric antigen receptor T-cell therapies have shown remarkable efficacy in leukemia and lymphoma patients who relapsed or were refractory to several prior treatments, but many challenges remain in the cancer cell therapy field. Strategies that may improve upon first-generation therapies were presented during the American Association for Cancer Research virtual meeting with encouraging early activity, […]




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Phase 3 Libtayo monotherapy trial halted early due to strong benefit in advanced non-small cell lung cancer

A Phase 3 study of Sanofi and Regeneron’s Libtayo (cemiplimab) as a monotherapy for advanced or metastatic non-small cell lung cancer (NSCLC) has been stopped early after showing strong overall survival benefit, it has emerged.




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FDA approval for Tabrecta in metastatic non-small cell lung cancer with METex14

The FDA has awarded marketing authorisation to Novartis for the Oral MET inhibitor Tabrecta for the first-line treatment of metastatic non-small cell lung cancer in patients whose tumors have a mutation that leads to MET exon 14 skipping (METex14), regardless of whether they have previously received any type of treatment.




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Key nose cells identified as likely COVID-19 virus entry points

Two specific cell types in the nose have been identified as likely initial infection points for COVID-19 coronavirus. Scientists discovered that goblet and ciliated cells in the nose have high levels of the entry proteins that the COVID-19 virus uses to get into our cells. The identification of these cells by researchers from the




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Bristol-Myers' CAR-T cell therapy meets with FDA delay

The submission of additional information, upon the request of the US regulator, has delayed the action…



  • Biotechnology/Bristol-Myers Squibb/Focus On/Immuno-oncology/lisocabtagene maraleucel/Regulation/Research/US FDA/USA

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Richmond Cell Manager of Sophisticated, Violent Fraudulent Document Ring Sentenced to 84 Months in Prison

Armando Gonzalez-Medina, 35, of Richmond, Va., was sentenced today to 84 months in prison, after pleading guilty to participating in a racketeering conspiracy and conspiring to possess, produce and transfer fraudulent identification documents.



  • OPA Press Releases

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Federal Prisoner Charged in California for Murder of Cellmate

A federal grand jury returned a two-count indictment today charging Samuel Stone, 32, with first degree murder and murder by a federal prisoner serving a life sentence.



  • OPA Press Releases

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Federal Courts Order Seizure of Three Website Domains Involved in Distributing Pirated Android Cell Phone Apps

The department said that this is the first time website domains involving cell phone app marketplaces have been seized.



  • OPA Press Releases

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Attorney General Eric Holder Delivers Remarks at the Leadership Excellence and Achievement Program (LEAP) Graduation Ceremony

It’s a pleasure to stand with you – and to help welcome so many colleagues and distinguished guests to the Great Hall – as we recognize the achievements, and celebrate the contributions, of the 39 accomplished LEAP graduates who make up our Class of 2013.




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RE: Cell banks for cell culture process development

From : Communities>>Regulatory Open Forum
The short answer is "yes" provided that the development cell bank was the source for the GMP bank and is comparable in terms of performance. However, the devil is in details and you need to evaluate "comparability" carefully between the development bank and the GMP bank with respect to the characterization data you plan to use for, e.g., to support GMP bank for production, etc. Two ICH guidance documents are useful to look at, Q7 Table 1 and Q5D. The US FDA generally follows ICH guidance but EMA [More]




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Phase 3 trial of Libtayo® (cemiplimab) as monotherapy for first-line advanced non-small cell lung cancer stopped early due to highly significant improvement in overall survival

- Libtayo decreased the risk of death by 32.4% compared to chemotherapy




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Libtayo® (cemiplimab) shows clinically meaningful and durable responses in second-line advanced basal cell carcinoma

Objective responses seen in 29% of patients with locally advanced basal cell carcinoma (BCC)




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Celltrion files application with EMA for adalimumab biosimilar

Celltrion has submitted an application to the European Medicines Agency (EMA) for its adalimumab biosimilar, currently known as CT-P17.




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COVID-19: T cells offer clues to the potential power of Roche's Actemra

The successful activation of T cells is critical to the immune system's ability to clear infections. A retrospective study in China found that COVID-19 patients had remarkably low T-cell counts in their blood, while some pro-inflammatory cytokines such as IL-6—which Roche’s Actemra targets—were elevated.




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Lilly-partnered AbCellera gets COVID-19 boost from Canadian government

After penning a deal with Eli Lilly last month with the aim to have an antibody in the clinic within four months, Canadian-based AbCellera has been given a financial boost by its government.




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Report says cellphone data suggests October shutdown at Wuhan lab, but experts are skeptical

U.S. and U.K. intel agencies are reviewing the private report, but intel analysts examined and couldn't confirm a similar theory previously.




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Yokogawa Releases SU10 Single Cellome Unit for Use in Biological Research

Yokogawa Electric Corporation (TOKYO: 6841) announces that it has developed the SU10 Single Cellome Unit, a device that uses a nanopipette to inject substances such as genes and drugs and aspirate intracellular materials at target locations in individual cells.




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Critical role of histone H3 lysine 27 demethylase Kdm6b in the homeostasis and function of medullary thymic epithelial cells




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CD9 induces cellular senescence and aggravates atherosclerotic plaque formation




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Compensation between Wnt-driven tumorigenesis and cellular responses to ribosome biogenesis inhibition in the murine intestinal epithelium




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Cell Death & Differentiation




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2-Hydroxyoleate, a nontoxic membrane binding anticancer drug, induces glioma cell differentiation and autophagy