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Killing 'sleeper cells' may enhance breast cancer therapy

The anti-cancer medicine venetoclax could improve the current therapy for estrogen receptor-positive (ER+) breast cancer, according to preclinical studies. The promising preclinical results for this 'triple therapy' have underpinned a phase 1 clinical trial in Melbourne, Australia, that is combining venetoclax with hormone therapy and CDK4/6 inhibitors in patients with ER+ breast cancer.




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EU Commission calls for state guarantees for vouchers for cancelled travel




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Experimental diabetes device works by killing gut cells with hot water

A device that carries hot water down a tube into the gut may help manage diabetes by killing overgrown gut cells that release hormones key to metabolising food




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Common herpes virus causes signs of Alzheimer's disease in brain cells

A study of brain cells in a dish adds to growing evidence that Alzheimer’s disease can be caused by herpes viruses, but antiviral treatment may help stop it




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BCG vaccine helps fight infections by boosting immune cell production

The BCG tuberculosis vaccine boosts the production of immune cells and this may explain how it protects newborns from dying of sepsis




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Brain cells reach out to each other through miniature cages

Mouse neurons trapped inside cages grow long appendages to connect to each other. Trapping the cells allows us to precisely control their growth




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‘Sacrificed in the name of COVID patients’: Tens of thousands affected by surgery cancellations

Almost 200,000 surgeries and other procedures were shelved indefinitely, as hospitals braced for a deluge that never quite materialized




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Accurate 3D imaging of sperm cells moving at top speed could improve IVF treatments

Researchers have developed a safe and accurate 3D imaging method to identify sperm cells moving at a high speed. The new method has the potential to significantly improve IVF treatments.




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See a 3D mouse brain with single-cell resolution

A manually constructed 3D atlas offers a cellular-level view of the entire mouse brain. This reference brain, called the Allen Mouse Brain Common Coordinate Framework (CCFv3), is derived from serial two-photon tomography images of 1,675 mice.




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More selective elimination of leukemia stem cells and blood stem cells

Hematopoietic stem cells from a healthy donor can help patients suffering from acute leukemia. However, the side effects of therapies are often severe. Researchers have now shown how human healthy and cancerous hematopoietic stem cells can be more selectively eliminated using immunotherapy instead of chemotherapy in mice. The aim is to test the new immunotherapy in humans as soon as possible.




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Newly discovered cell type plays crucial role in immune response to respiratory infections

With a discovery that could rewrite the immunology textbooks, an international group of scientists have identified a new type of antigen-presenting immune cell.




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The moment coronavirus infects a healthy cell captured under microscope

Read our live updates on coronavirus HERE Coronavirus: The symptoms




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Oktoberfest cancelled due to coronavirus pandemic

Oktoberfest has been cancelled this year because of the coronavirus pandemic.




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Nose cells identified as entry points for coronavirus

Two nose cells have been identified as the first points at which Covid-19 enters the human body.




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BBC's Big Night In raises £27m for charity as Chancellor Rishi Sunak says Government will match all donations

Some of Britain's most famous faces united to entertain the nation as part of BBC One's Big Night In , which raised more than £27 million to help support vulnerable people during the coronavirus pandemic.




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Chelsea Flower Show unveils online displays and exhibitions after event cancelled

The Royal Horticultural Society (RHS) said this summer would mark its first ever "virtual" version of the event at Royal Hospital Chelsea, London.




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Airlines should be able to issue vouchers instead of cash refunds for cancelled flights, EU members say

Airlines should be able to issue vouchers instead of cash refunds for cancelled flights, according to 12 EU member states who have requested a change in the rules to help carriers.




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'You could be someone's only hope': A stem cell donor campaigning to beat blood cancer





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Shadow chancellor Anneliese Dodds interrupted by daughter in live interview during virus lockdown




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Former Chancellor Philip Hammond calls on Government to reopen economy soon or face disaster

But in one sign of a turning tide in Number 10, the UK Government is reportedly considering a proposal to allow Brits to meet up with small "bubbles" of up to 10 of their closest family or friends.




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Recovery from coronavirus crisis will take years, ex-chancellors Kenneth Clarke and Norman Lamont warn

Britain will not enjoy a "V-shaped bounce" out of the crisis caused by coronavirus but will take years to recover fully, two former chancellors today warned.




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Coronavirus: Cancellation of CFL season is ‘most likely scenario’, commissioner says

"Our best-case scenario for this year is a drastically truncated season," Randy Ambrosie said. "And our most likely scenario is no season at all.''




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Video game confab E3 cancelled over coronavirus fears

The Electronic Entertainment Expo, the signature video game industry event held each June, has been cancelled because of fears of the coronavirus.

      




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Quebec police investigating possible link between cell tower fires and 5G coronavirus conspiracy theories

Quebec provincial police are investigating whether at least two cellphone tower fires north of Montreal could be linked to conspiracy theories that 5G wireless technology caused the coronavirus pandemic.




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Marvel actor Deborah Ann Woll 'struggling with self-doubt' following Daredevil cancellation: 'I haven't had an acting job since'

'If I'm not acting, I'm not sure who I am,' the True Blood star said




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Love Island cancelled: ITV axes summer series over coronavirus risk

Producers have reportedly found it impossible to arrange filming amid the coronavirus pandemic




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'It's a really weird realisation': when cancelled holidays come with silver linings

From accidentally making money due to currency fluctuations, to paying down debt, for some Australians cancelled overseas trips have had surprising windfalls

From June 2018 to June 2019, the Australian Bureau of Statistics says Australians made a record 11.3 million trips overseas – double the number of trips just 10 years ago. In the wake of the Covid-19 pandemic, millions of Australians have been forced to cancel or alter their international travel plans.

This has left many Australians struggling to get refunds from travel providers. Flight Centre was charging $300 in processing fees per person, in some cases leading to fees that cost more than the value of the refund, until the Australian Competition and Consumer Commission stepped in and threatened legal action, causing the company to waive fees for trips cancelled by travel providers. The ACCC also warned travel providers against retroactively changing their cancellation policies after tour companies including Topdeck and Intrepid attempted to retrospectively apply updated refund policies that would force customers to take credit rather than cash for cancelled trips.

Continue reading...




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Lockdown Letters: A cancelled wedding causes a change of heart

In the latest instalment in our series of thoughts and reflections during lockdown, Suzannah Ramsdale reassesses what's actually important




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Coronavirus travel: Expert advice on how to deal with refunds and booking cancellations

Holidays have been ruined, future bookings hang in the balance and Brits are still stranded overseas. We asked Holly Rubenstein, host of The Travel Diaries podcast, for help...





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Music Canada statement regarding JUNO Week 2020 Cancellation

The JUNOS are a nationwide celebration of Canadian music. But they are far more than what Canadians see on a Sunday evening telecast once a year. JUNO Week provides opportunities for artists and the rest of the music community from every corner of the country to gather and connect, to perform, and to be honoured […]

The post Music Canada statement regarding JUNO Week 2020 Cancellation appeared first on Music Canada.




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How the Premier League table would look had matches not been cancelled

Predict the results of the matches that should have been played this weekend...




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How the Premier League table would look had matches not been cancelled

It's been four weeks since a ball was last kicked in the Premier League.




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Coronavirus sport news LIVE: International Champions Cup cancelled, Kenny Dalglish tests positive for Covid-19

Welcome to the Evening Standard's LIVE coverage as the coronavirus crisis continues to heavily impact sport across the globe.




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West Ham and Crystal Palace pre-season tournament in Australia cancelled due to coronavirus

West Ham and Crystal Palace's pre-season tournament in Australia has been cancelled.




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National League clubs vote to end 2019-20 season with remaining matches cancelled

National League clubs have voted in favour of ending the 2019-20 season at its current point.




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Coronavirus sport news LIVE: Arsenal players 'pressured into pay cut', Dutch football likely to be cancelled

Welcome to the Evening Standard's LIVE coverage as the coronavirus crisis continues to heavily impact sport across the globe.




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Hakim Ziyech set to seal Chelsea transfer on July 1 as Eredivisie is cancelled

Hakim Ziyech will be free to join Chelsea without delay this summer after the Eredivisie season was cancelled.




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Eredivisie cancelled: No title for Ajax with no promotion or relegation from Dutch football's top league

The 2019/20 Eredivisie season has been cancelled, meaning Duch league leaders Ajax will miss out on the title.




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Eredivisie cancelled: Why this is bad news for Liverpool ahead of Premier League decision

The Eredivisie season has been cancelled, with the title, relegation out of and promotion into the league scrapped.




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Coronavirus sport news LIVE: Eredivisie cancelled, cricket season delayed until July, Champions League latest

Welcome to the Evening Standard's LIVE coverage as the coronavirus crisis continues to heavily impact sport across the globe.




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Edwin van der Sar reflects as Eredivisie cancellation ends Ajax title hopes

Ajax CEO Edwin van der Sar has admitted to his disappointment after the Eredivisie was cancelled on Friday, meaning his side will not be awarded the title.




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Alan Pardew denies receiving bonus as ADO Den Haag avoid relegation due to Eredivisie cancellation

Alan Pardew insists he will not take a bonus from ADO Den Haag after the Dutch outfit avoided relegation from the Eredivisie.




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Ligue 1 season cancelled in France as government confirms ban on football until September

The French football season has been ended after the country's government announced that no large sporting events will be allowed to take place until at least September, even if they are behind closed doors.




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Alan Pardew leaves ADO Den Haag after just four months as manager following Eredivisie cancellation

ADO Den Haag have announced that Alan Pardew and his coaching team have left the club by mutual consent after four months in charge.




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PSG prepared to play home Champions League matches abroad after Ligue 1 cancellation, says Nasser Al-Khelaifi

Paris Saint-Germain will play their remaining home Champions League matches overseas if it is not possible to do so in France, according to president Nasser Al-Khelaifi.




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Ligue 1 cancellation gives huge title boost to Liverpool after PSG are crowned French champions

Ligue 1 became the second major European league to announce its cancellation due to the coronavirus pandemic on Tuesday, following the Eredivisie's termination last week.




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Manchester United star Marcus Rashford sends heartfelt message to youth teams after season cancelled

Marcus Rashford has urged Manchester United's academy starlets to stay positive and 'remember why they fell in love with football' after their season was cut short because of the coronavirus outbreak.




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French League to take out loan to cover loss of TV rights money after season cancellation

The Ligue de Football Professionnel (LFP) have confirmed they will help support Ligue 1 and Ligue 2 clubs financially following the cancellation of the season with a state-guaranteed loan to cover lost television rights money.