nc meso-Substituted AB3-type phenothiazinyl porphyrins and their indium and zinc complexes photosensitising properties, cytotoxicity and phototoxicity on ovarian cancer cells By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00601A, Research Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Brém Balázs, Bianca Stoean (Vasile), Éva Molnár, Eva Fischer-Fodor, Ovidiu Bălăcescu, Raluca Borlan, Monica Focsan, Adriana Grozav, Patriciu Achimaş-Cadariu, Emese Gál, Luiza GainaNew meso-substituted AB3-type phenothiazinyl porphyrins and ferrocenylvinyl phenothiazinyl porphyrin were synthesised by Suzuki–Miyaura and Mizoroki–Heck cross-coupling reactions, respectively.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
nc Discovery of N-substituted-2-oxoindolin benzoylhydrazines as c-MET/SMO modulators in EGFRi-resistant non-small cell lung cancer By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00553H, Research ArticleStefano Tomassi, Benito Natale, Michele Roggia, Luisa Amato, Caterina De Rosa, Carminia Maria Della Corte, Emma Baglini, Giorgio Amendola, Anna Messere, Salvatore Di Maro, Elisabetta Barresi, Federico Da Settimo, Maria Letizia Trincavelli, Fortunato Ciardiello, Sabrina Taliani, Floriana Morgillo, Sandro CosconatiNon-small cell lung cancer (NSCLC), the leading cause of cancer-related mortality worldwide, poses a formidable challenge due to its heterogeneity and the emergence of resistance to targeted therapies.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
nc Light enhanced cytotoxicity and antitumoral effect of a ruthenium-based photosensitizer inspired from natural alkaloids By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00600C, Research Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Gennaro Sanità, Maria Laura Alfieri, Barbara Carrese, Serena Damian, Vincenza Mele, Gaetano Calì, Brigida Silvestri, Sebastiano Marra, Susan Mohammadi, Giuseppina Luciani, Paola Manini, Annalisa LambertiBiological assays carried out on melanoma and breast cancer cells highlighted the role of light in boosting the cytotoxic effect of a ruthenium complex featuring a dihydroisoquinoline ligand suggesting applications in photodynamic therapy.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
nc SIGMAP: an explainable artificial intelligence tool for SIGMA-1 receptor affinity Prediction By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4MD00722K, Research Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Maria Cristina Lomuscio, Nicola Corriero, Vittoria Nanna, Antonio Piccinno, Michele Saviano, Rosa Lanzilotti, Carmen Abate, Domenico Alberga, Giuseppe Felice MangiatordiDeveloping sigma-1 receptor (S1R) modulators is considered a valuable therapeutic strategy to counteract neurodegeneration, cancer progression, and viral infections, including COVID-19. In this context, in-silico tools capable of accurately predicting...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
nc Adjuvant strategies to tackle mcr-mediated polymyxin resistance By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00654B, Review ArticleMadison R. Nuske, Junlang Zhong, Renjie Huang, Vijayalekshmi Sarojini, Jack L. Y. Chen, Christopher J. Squire, Mark A. T. Blaskovich, Ivanhoe K. H. LeungThe emergence of the mobile colistin resistance (mcr) gene is a significant threat contributing to the worldwide antibiotic resistance crisis. This review discusses adjuvant strategies to restore polymyxin sensitivity in these resistant bacteria.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
nc Changes in train services notified due to demolition of old bridge near Tiruchi junction By www.thehindu.com Published On :: Tue, 05 Nov 2024 17:30:53 +0530 Full Article Tiruchirapalli
nc Data crucial for building climate resilience, says ISRO scientist By www.thehindu.com Published On :: Tue, 05 Nov 2024 19:40:51 +0530 Full Article Tiruchirapalli
nc Plea to include ‘panneer karumbu’ in Pongal gift hamper By www.thehindu.com Published On :: Wed, 06 Nov 2024 19:41:17 +0530 Full Article Tiruchirapalli
nc HC directs authorities to maintain park and ensure no encroachment By www.thehindu.com Published On :: Wed, 06 Nov 2024 21:09:52 +0530 Full Article Madurai
nc Property owners block the entrance to Balasubramanya temple in Karur By www.thehindu.com Published On :: Thu, 07 Nov 2024 17:35:45 +0530 Full Article Tiruchirapalli
nc Govt. urged to extend last date to pay crop insurance premium by farmers By www.thehindu.com Published On :: Thu, 07 Nov 2024 17:45:02 +0530 Full Article Tiruchirapalli
nc Peravurani farmers’ market starts functioning By www.thehindu.com Published On :: Fri, 08 Nov 2024 18:46:38 +0530 Full Article Tiruchirapalli
nc High-level committee formed to facilitate clearances for companies that signed MoU, says Minister By www.thehindu.com Published On :: Fri, 08 Nov 2024 18:56:40 +0530 Constant monitoring was being done now from the time of signing of MoUs to providing employment in new industrial units, says Industries Minister T.R.B. Rajaa Full Article Tiruchirapalli
nc Advanced baggage handling system introduced in Tiruchi airport By www.thehindu.com Published On :: Sat, 09 Nov 2024 18:01:36 +0530 Full Article Tiruchirapalli
nc 557: ChatGPT, Conferences, Fidgets on the Web, and Modern CSS in Real Life By shoptalkshow.com Published On :: Mon, 20 Mar 2023 07:01:51 +0000 When will AI be able to tell you the risk / reward of cleaning up trees? Are conferences back? Bringing fidgets to the web, internet as an anxiety machine, and Chris is working on talk on modern CSS in real life. Full Article All Episodes AI chatgpt Conferences CSS fidgets
nc 570: Haircut Maintenance, Dave’s Bookshelf, Lazy Loading, and APIs By shoptalkshow.com Published On :: Mon, 19 Jun 2023 08:00:42 +0000 We're talking Dave's new haircut, playing Hondo, what Dave uses for images on his bookshelf page, lazy-loading thoughts, vh vw follow up, eyeball tracking updates, loading website with js, Vue transitions, charging for API access, and do you cross post, one post, or no post on social media in 2023? Full Article All Episodes api lazyloading transition
nc 572: Text Sqwunch Property, Figma Developer Mode, Stripe Elements By shoptalkshow.com Published On :: Mon, 03 Jul 2023 08:24:15 +0000 Show DescriptionDave reports back from the Figma Conference, how to build a better developer to designer bridge, do clients really want to update their website, using Stripe in 2023, permissions and sharing, and are you feeling overwhelmed by CSS in 2023? Listen on Website →Links Config 2023 | Figma’s Annual Conference Figma Visual Studio Code […] Full Article All Episodes CSS figma stripe
nc 589: CSS Functions, Read It Later, Making Money in Business, and More By shoptalkshow.com Published On :: Mon, 30 Oct 2023 07:28:10 +0000 A quick bit of union news follow up, CSS function round up, Read It Later inside Feedbin, fun uses for a Stream Deck+, how to turn up the money dial in your own business, and having the audacity to call yourself a publisher. Full Article All Episodes CSS Feedbin Making Money Read It Later
nc 591: Cascade Layers, CSS Functions, and more CSS with Miriam Suzanne By shoptalkshow.com Published On :: Mon, 13 Nov 2023 10:11:50 +0000 Miriam Suzanne stops by to talk about CSS updates and news on container queries, rolling out cascade layers, !important things to remember, custom properties, exit animations, CSS functions, state queries, and more. Full Article All Episodes cascade layers CSS css functions exit animations
nc 603: Deno, React Alternatives, and Copilot Concerns with Triple Threat Josh Collinsworth By shoptalkshow.com Published On :: Mon, 19 Feb 2024 09:22:07 +0000 Josh (or Jsoh) stops by to talk about his work at Deno, recent blog posts on Copilot, why Svelte is awesome and React is not, Apple and PWA, and building word games on the web. Full Article All Episodes Deno GitHub copilot pwa
nc 607: Astro Launches an Integrated Database By shoptalkshow.com Published On :: Mon, 18 Mar 2024 08:39:41 +0000 Fred K. Schott stops by to talk about Astro announcement of Astro DB, the pluses and minuses of it, whether you have to always use the database with Astro DB, how to migrate data, seeding your database, upgrading the database, and what about Astro DB pricing? Full Article All Episodes Astro astro db database
nc 619: Svencodes By shoptalkshow.com Published On :: Mon, 10 Jun 2024 08:27:33 +0000 Sven Neumann aka Sven Codes talks with us about SudokuPad, developing a cross-platform app, integrating new puzzles and features, the benefits of being easy to use, building a community, and monetizing an app while not upsetting your user base. Full Article All Episodes app development sudoku
nc The fight against encroachment By www.thehindu.com Published On :: Fri, 04 Sep 2015 16:58:16 +0530 No one has the right to use precious road space as their private storage yard. Full Article Property Plus
nc Style and substance, from waste By www.thehindu.com Published On :: Fri, 22 Apr 2016 22:57:40 +0530 Many architects with green ideologies have converted waste to usable construction material, some of it in the most innovative manner. Full Article Green Living
nc Homes with a ‘conscience’ By www.thehindu.com Published On :: Fri, 29 Apr 2016 15:26:07 +0530 Around 5,000 homes in the city shun BWSSB water supply and produce enough power of their own. By M.A. Siraj Full Article Property Plus
nc Gunning for a slice of billion-dollar defence contracts By www.thehindubusinessline.com Published On :: Sun, 29 Sep 2024 20:36:00 +0530 How a college project birthed a bootstrapped manufacturer of components for the armed forces Full Article Emerging Entrepreneurs
nc A sporty knock from India Inc By www.thehindubusinessline.com Published On :: Sun, 29 Sep 2024 20:53:00 +0530 A growing crop of corporates are making serious investments in sports and beginning to reap the rewards, too Full Article Corporate File
nc The delicate balance in doctor-patient interaction By www.thehindubusinessline.com Published On :: Sun, 06 Oct 2024 22:06:15 +0530 How clear communication and accountability in healthcare can significantly improve patient outcomes Full Article Pulse
nc Carbon credits to boost incomes of Jharkhand village farmers By www.thehindubusinessline.com Published On :: Sun, 13 Oct 2024 20:00:00 +0530 The Birsa Harit Gram project serves as a potential model for agro-forestry, which is gaining ground because the buyers of carbon credits prefer — pay a premium — for credits based on Nature Based Solution, as opposed to offsetting projects like renewable energy or projects like carbon capture. Full Article Clean Tech
nc Why banks are branching furiously By www.thehindubusinessline.com Published On :: Sun, 13 Oct 2024 20:13:00 +0530 From financial inclusion to wooing back savings deposits, lenders have reasons to reject digital-only mode Full Article Current Account
nc New venture Zerofifty from ad veterans wants to simplify the agency model By www.thehindubusinessline.com Published On :: Sun, 20 Oct 2024 10:46:58 +0530 ZeroFifty Mediaworks, set up by three ad veterans, wants to bring in Bandra vibes into the agency model Full Article Marketing
nc How Ratan Tata pushed for evidence-led ayurveda By www.thehindubusinessline.com Published On :: Sun, 20 Oct 2024 20:38:00 +0530 Ratan Tata sought to promote research that could validate ayurveda through contemporary science Full Article Pulse
nc Senior feline resident: Defib stays at his ambulance station By www.thehindubusinessline.com Published On :: Sun, 20 Oct 2024 21:19:43 +0530 Online petition halts re-homing of 16-year-old cat in London Full Article Pulse
nc Indo National plans battery of home-care launches By www.thehindubusinessline.com Published On :: Sun, 27 Oct 2024 14:00:42 +0530 The maker of Nippo batteries plans to innovate in its core business and get into LED bulbs Full Article Corporate File
nc Shifting gift preferences By www.thehindubusinessline.com Published On :: Sun, 27 Oct 2024 14:44:59 +0530 Employees today prefer personalised gifts, and India Inc is taking cognisance Full Article Corporate File
nc How Jio is powering Reliance’s media, entertainment biz By www.thehindubusinessline.com Published On :: Sun, 27 Oct 2024 14:46:07 +0530 Despite a late entry into telecom, digital services, and media, Reliance has raced to the top Full Article Corporate File
nc Why more NRIs are buying health insurance in India By www.thehindubusinessline.com Published On :: Sun, 03 Nov 2024 19:13:28 +0530 The number of NRIs buying health insurance from India has increased steadily over the past three years Full Article Pulse
nc Spotlight on ways to end violence against children By www.thehindubusinessline.com Published On :: Sun, 03 Nov 2024 19:24:25 +0530 Full Article Pulse
nc Concussion: FIFA kicks off ‘suspect and protect’ drive By www.thehindubusinessline.com Published On :: Sun, 03 Nov 2024 19:30:47 +0530 Campaign raises awareness that concussion is a traumatic brain injury and a risk to every player on the pitch Full Article Pulse
nc Nvidia: The lynchpin of the AI revolution By www.thehindubusinessline.com Published On :: Sat, 09 Nov 2024 18:18:47 +0530 The meteoric rise of the Santa Clara-headquartered chipmaker is powered by bold innovation Full Article Corporate File
nc Trump presidency casts long shadow over climate summit By www.thehindubusinessline.com Published On :: Sun, 10 Nov 2024 19:27:32 +0530 The return of the climate denier as head of the world’s biggest greenhouse gas emitter threatens to throw net-zero negotiations into disarray once again Full Article Clean Tech
nc ADB increases climate finance after US, Japan give world's first sovereign guarantees By www.thehindubusinessline.com Published On :: Mon, 11 Nov 2024 10:38:46 +0530 Full Article Economy
nc HC refuses to entertain plea to enhance funds allocated to MCD councillors By www.thehindu.com Published On :: Tue, 05 Nov 2024 17:04:14 +0530 The Hight Court expressed surprise that members of the Legislative Assembly (MLAs) and Municipal Corporation of Delhi (MCD) councillors were approaching courts with their grievances and asked them to raise the issue in the House or before the public Full Article Delhi
nc Cannot change rules of the game once recruitment to public services commences: SC By www.thehindu.com Published On :: Thu, 07 Nov 2024 19:49:04 +0530 The Constitution Bench says laws, rules and procedure governing recruitments to public services must be governed by the overarching principles of fundamental rights of equality and non-discrimination Full Article India
nc Delhi cop Nidhin Valsan’s inspiring journey from arresting cancer to Ironman finish line By www.thehindu.com Published On :: Fri, 08 Nov 2024 02:05:22 +0530 Diagnosed with stage 4 non-Hodgkin’s lymphoma in 2021, IPS officer Nidhin Valsan resurrected himself by competing the Ironman triathlon and writing his memoir because he hopes to be a good influence on other cancer patients Full Article Delhi
nc Kejriwal gives clarion call to sarpanchs in Punjab to wipe out curse of drugs By www.thehindu.com Published On :: Fri, 08 Nov 2024 20:56:50 +0530 Opposition says AAP government has ‘mishandled and mismanaged’ every aspect of State administration Full Article Punjab
nc Delhi govt okays proposal, 10000 Civil Defence Volunteers to return for anti-pollution work: Atishi By www.thehindu.com Published On :: Sat, 09 Nov 2024 16:27:20 +0530 Within two-three days of the registration, the CDVs will be deployed on duties like management of pollution hotspots, preventing dust pollution and garbage burning, she said in a press briefing Full Article Delhi
nc One dead, one injured in two firing incidents in Delhi within 10 minutes By www.thehindu.com Published On :: Sat, 09 Nov 2024 16:49:04 +0530 The two incidents of firing in northeast Delhi leave one dead and one injured; three suspects apprehended by police Full Article Delhi
nc A year after being sacked, 10,000 civil defence volunteers in Delhi set to return to work By www.thehindu.com Published On :: Sun, 10 Nov 2024 00:27:29 +0530 The former bus marshals, dismissed last year on grounds of ‘improper recruitment process’, to be deployed for anti-pollution measures for 4 months; will send proposal to L-G to make them permanent employees: CM; our MPs put pressure on Atishi, ‘forced’ her to announce the reinstatement: BJP Full Article Delhi
nc Delhi Transport Minister Kailash Gahlot announces two new bus routes for outer Delhi By www.thehindu.com Published On :: Mon, 11 Nov 2024 01:31:06 +0530 Full Article Delhi