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Treatment Advances, Predictive Biomarkers Stand to Improve Bladder Cancer Care

Recent advances in bladder cancer treatments may offer hope of curative care to more patients, including those with high-risk localized, muscle-invasive disease, according to a New England Journal of Medicine editorial published by Matthew Milowsky, MD, FASCO, a bladder cancer expert at UNC School of Medicine and UNC Lineberger Comprehensive Cancer Center.




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Exposure to Marijuana in the Womb May Increase Risk of Addiction to Opioids Later in Life, Study Finds

University of Maryland School of Medicine Researchers Identify Neurobiological Changes Leading to Increase Release of the Brain Chemical Dopamine and Its Target Neurons Linked to Addiction-Like Behavior With the increased legalization of recreational cannabis, as many as 1 in 5 pregnant women in the U.S. are now using the drug to help with morning sickness, lower back pain or anxiety.




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New Study Links Air Pollution with Increased Risk of Spontaneous Preterm Births

Vulnerable populations without access to green space and exposed to higher temps were most affected




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Vaccine Shows Promise Against Aggressive Breast Cancer

A small clinical trial shows promising results for patients with triple-negative breast cancer who received an investigational vaccine designed to prevent recurrence of tumors. Conducted at Washington University School of Medicine in St. Louis with a therapy designed by WashU Medicine researchers, the trial is the first to report results for this type of vaccine -- known as a neoantigen DNA vaccine -- for breast cancer patients.




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McMaster University Researchers Uncover Potential Treatment for Rare Genetic Disorders

In a groundbreaking study, researchers at McMaster University have identified a potential treatment for Sandhoff and Tay-Sachs diseases--two rare, often fatal lysosomal storage disorders that cause progressive damage to nerve cells in the brain and spinal cord. After years of investigating the diseases' underlying mechanisms, the research team has identified an existing FDA-approved drug that could significantly improve quality of life for affected patients and their families.




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How Does Legal Status Inform Immigrant Agency During Encounters of Workplace Incivility?




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Expert Available: What to Expect on the Regulatory Front of a Second Trump Presidency

U.S. President-elect Donald Trump has tapped Elon Musk and Vivek Ramaswamy to lead a new commission on cutting government spending and regulation. ...




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How Taurus and Aquarius Compatibility Can Thrive Despite Differences

Discover Taurus and Aquarius compatibility in love, friendship, and more. Uncover their unique strengths, challenges, and potential for a balanced relationship




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National College Entrance Exam Set for Thursday

[Domestic] :
The annual College Scholastic Ability Test(CSAT) is taking place at some 13-hundred test sites across the nation on Thursday.  The state-administered college entrance exam, known in Korean as the Suneung, begins with a Korean language test at 8:40 a.m., followed by tests on math, English, Korean history ...

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S. Korea’s Spy Agency: N. Korean Troops Fighting in Russia

[Inter-Korea] :
South Korea’s spy agency said Wednesday that North Korean troops dispatched to Russia have moved to the front-line region of Kursk and are “already engaging in combat” against Ukraine. The National Intelligence Service(NIS) said North Korean soldiers dispatched to Russia have moved to the Kursk ...

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‘Killer Questions’ Excluded from 2025 College Entrance Exam

[Domestic] :
The head of the panel that devised the college entrance exam said this year’s test excluded so-called killer questions. Choe Joong-chul, chief of the 2025 College Scholastic Ability Test(CSAT) committee, made the statement Thursday in a press briefing, saying this year’s questions maintained an ...

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Yoon Highlights ‘Strategic Importance’ of Latin America ahead of Trip to Peru, Brazil

[Politics] :
President Yoon Suk Yeol said his first official trip to Latin America carries great significance for the expansion of South Korea’s vision as a “global pivotal state” toward the Latin American region. The president, who is set to depart for Peru and Brazil to attend the Asia-Pacific Economic ...

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Top Court Upholds Suspended Sentence for Ex-Lawmaker Who Embezzled Donations Meant for Victims of Sex Slavery

[Politics] :
The Supreme Court has upheld a suspended prison term for former Rep. Youn Mee-hyang, who was convicted of embezzling donations to an advocacy group for South Korean victims of sexual slavery during World War II. On Thursday the top court upheld the 18-month sentence, suspended for three years, after ...

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Abductees’ Families Plan to Launch Leaflets Toward N. Korea

[Domestic] :
A group representing families of South Koreans abducted by North Korea plans to launch leaflets toward North Korea from waters off the coast of Goseong, Gangwon Province. The group made the announcement Thursday, having called off plans to launch leaflets last month due to opposition from local ...

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Annual National College Entrance Exam Underway

[Domestic] :
The 2025 College Scholastic Ability Test(CSAT) is underway at some 13-hundred test sites across the nation on Thursday, with some 522-thousand taking part in the exams. The state-administered college entrance exam, known in Korean as the Suneung, began with a Korean language test at 8:40 a.m. Subjects also ...

[more...]




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Annual College Entrance Exam Sees Record Number of Retakers

[Politics] :
Anchor: The annual state-administered College Scholastic Aptitude Test took place Thursday. This year, around 522-thousand people registered to take the exam at one-thousand-282 locations across the country. That includes a record number of retakers, after the quota increased for medical school ...

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Finance Minister Vows Active Measures to Curb FX Market Volatility if Necessary

[Economy] :
Finance Minister Choi Sang-mok said Thursday that the government will take “active measures” in the event of excessive volatility in the foreign exchange market, as the South Korean won weakened past the psychological threshold of 14-hundred won against the U.S. dollar. The minister made the “verbal ...

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BANCOMAT, Bizum, and MB WAY launch EuroPA

European mobile payment solutions BANCOMAT,



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FXBO partners with BridgerPay to enhance fintech solutions

FX Back Office (FXBO) has partnered with



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Mastercard launches Biz360 to support small business operations

Mastercard has introduced Biz360, a digital platform...




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MoonPay brings fiat balances to decentralized crypto

MoonPay, a crypto payments...




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Using Wi-Fi like sonar to measure speed and distance of indoor movement




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NSF Science Now: Episode 65

NSF Science Now: Episode 65




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The National Science Foundation: Creating knowledge to transform our future

The National Science Foundation: Creating knowledge to transform our future




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New science blooms after star researchers die, study finds




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Freelancer? Avoid these '7 deadly sins' at tax time.

The organized freelancer will make sure the amount here is right.; Credit: Photo by Great Beyond via Flickr Creative Commons

Brian Watt

For freelancers, consultants, actors and other self employed people, life gets complicated this time of year. Digging around for the paperwork to fill out tax forms practically qualifies as exercise.

"They have a nightmare trying to find receipts," said accountant Tristan Zier.

Zier founded Zen99 to help freelancers manage their finances, including filing their taxes.  His most important advice to freelancers: keep track expenses and receipts year round rather than pursuing a paper chase as April 15 nears.  

"When they can’t find receipts, they can’t write off their expenses," he said. "And they’re paying more money to the government instead of keeping it for themselves."

Zier and others have come up with a lists of common mistakes freelancers make at tax time. 

Here are seven don't - or, deadly sins, for freelances at tax time:

  1. Not knowing what they owe.  Zier says there are 20 different 1099 forms that get sent out to workers to track freelance gigs.  One of them is the 1099-K, which only has to be sent to you by a company in paper form if you make over $20,000. "People think, 'Great, no paper form, no taxes on that," says Zier. "Big mistake there.  You still have to self-report the income."   
  2. Not knowing WHEN they owe.  For freelancers who owe more than $1,000 in taxes for a year, tax time comes more often than just April 15.  They have to pay taxes quarterly. But then it's not coming out of paychecks like it does for permanent employees. 
  3.  Not tracking and writing off the right types of business expenses. Zier says many freelancers fail to realize they can write off part of their cell phone bill as a business expense.  Expenses vary by the type of work.  "A rideshare driver's biggest expense will be related to their car, while a web developer's biggest expense might be their home office," Zier says. "Figuring out what expenses are important to your type of work is important is maximizing your tax savings."

  4. Writing off personal expenses.  This goes back to that cell phone.  If you use the same phone for personal and business purposes, don't be tempted to write the whole bill off. Estimate the amount you use it for your work. The same goes for your vehicle. Don't go trying to write off miles driven to the beach. 

  5. The Double No-No: counting expenses twice.  Speaking of vehicles, Zier says most people use the Standard Mileage Rate ($0.56/mile for 2014), which factors in gas, repairs and maintenance and other costs like insurance and depreciation. But if you use this rate, you can't also expense your gas receipts and repair bills.  

  6. Employee AND employer.  At lifeofthefreelancer.com, financial consultant Brendon Reimer reminds freelancers they play both roles. For regular employees, Federal, State, and payroll taxes are withheld from a paycheck, and distributed on the employee’s behalf. It's how Social Security and Medicare are funded. The IRS mandates that the employer must pay half of every employee’s payroll tax, and the employee is responsible for the other half.  Independent contractors have to handle both halves.  "The IRS does give you a small benefit by letting you deduct the half that you pay yourself as a business expense," Reimer writes. Zier said the freelancer's sin here is believing he or she pays more taxes than the regular working stiff.  

  7. Not keeping adequate records. The IRS requires you to keep proof of all business receipts, mileage, etc.  If you can't show these, the IRS  could refute the expense and force you to pay back taxes. Zier says the good news is there are other ways to prove expenses if you've lost the receipt. A bank or credit card statement with the date and location might do the trick. "The IRS is surprisingly accommodating if you are doing your best," Zier says. "If you're being a headache, they're going to be a headache as well." 

In separate reports, Zen99 and the consumer finance web site nerdwallet ranked Los Angeles the best city for freelancers.

Each considered housing and health care costs, the percentage of freelancers in an area as factors. Zier said even before the sharing economy began to take off, the entertainment industry and growing tech scene were already strong sources of freelance gigs in L.A.

"Even back in 2012, L.A. had twelve percent of people report themselves as self-employed on the Census," Ziers said.   "You know your Ubers and companies like that  are really bringing a lot of attention to the contractor market, but it was a very robust community before."

 

This content is from Southern California Public Radio. View the original story at SCPR.org.




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Ports see worst congestion since 2004 because of work stoppage

In this Jan. 14, 2015, photo, shipping containers are stacked up waiting for truck transport at the Port of Los Angeles.; Credit: Damian Dovarganes/AP

Ben Bergman

The Ports of Los Angeles and Long Beach reopened Monday after ship loading and unloading was suspended this weekend because of a long-running labor dispute, which caused the worst delays the ports have seen in more than a decade.

The stoppage led to a queue of 31 ships, according to Kip Louttit, Executive Director of the Marine Exchange of Southern California, the agency that manages ship traffic.

“It’s quite unusual,” said Louttit.

There was a 10-day lockout at the ports in 2002, and an eight-day strike by port clerks in 2012, but even during those standoffs, the queue never exceeded 30 vessels.

The last time that happened was in 2004, because of staffing shortages at the Union Pacific Railroad. Some 65 ships were anchored, "backed up halfway down to San Diego, like 50 miles down the coast," Art Wong, spokesperson for the Port of Long Beach, told JOC.com, a container shipping and international supply chain industry website.

By Monday afternoon, the situation had improved some: 24 vessels were waiting to dock.

Louttit says all those ships waiting at sea means cargo is not getting where it needs to be.

“We had an automaker from the Midwest stop by, trying to get an idea of what the flow would be, because their plants are running out of parts to make cars,” he said.

Los Angeles Councilman Joe Buscaino, who supports the dockworkers union, called on both sides to reach an agreement quickly. To underscore the delays the dispute is having, he travelled a mile and a half out to sea Monday morning to count the number of anchored ships for himself. He posted a video of his trip on Youtube:

 

This content is from Southern California Public Radio. View the original story at SCPR.org.




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WWE looks to springboard from Wrestlemania 31 into new audiences

Brock Lesnar after losing his championship in the main event of Wrestlemania 31.; Credit: WWE

Mike Roe

World Wrestling Entertainment held their annual Wrestlemania show last weekend in Northern California, the culmination of another year's worth of spectacle. According to the company, it was their highest grossing event of all-time, drawing $12.6 million, with an official attendance placing it fifth on their list of all-time crowds for the event. The show was headlined by former UFC Heavyweight Champion Brock Lesnar going up against up-and-coming star (and a relative of Dwayne "The Rock" Johnson) Roman Reigns.

WWE Network

It comes at a time when the company has embarked on a new way of making money: their over-the-top online programming provider, the WWE Network, where fans can pay $9.99 a month to see programming including what formerly used to cost $45 for most shows and $60 for Wrestlemania. They're one year in now on gambling that enough fans will want the Network that it will ultimately make them more money in the long-term, despite losing that pay-per-view revenue. Wall Street doesn't appear to be buying it — after announcing the day after Wrestlemania that they'd hit 1.3 million subscribers, WWE's stock took a significant loss.

"The point is not whether it's real or if it's staged. The point is, are you entertained by it, or not?" former WWE announcer Jim Ross told KPCC in an interview. WWE is looking for more fans to be entertained enough to plunk down $9.99 for all the pro wrestling content they want.

NXT

They're also in a transitional period with their audiences. They've launched a new show that's only on the Network called "NXT," turning their minor league into a program targeting hardcore pro wrestling fans with a different style of show than the more family-targeted "Raw" and "Smackdown." It's also where they groom potential future stars, many of whom seem to break the mold of some of the traditional stars on WWE's main roster.

They're signing up talent that's been getting buzz on the independent circuits, trying to create their own underground movement that hopefully spells money, and taking the NXT brand on tour for the first time. On the Raw after Wrestlemania, several NXT stars made their debut on the main roster. That follows a sell-out crowd (albeit at a smaller 5,000 seat venue) on the Friday night before Wrestlemania for a non-televised NXT show.

Give Divas a chance

WWE also faces cultural forces pushing them in new directions, including a difference in how society deals with gender. When WWE executive Stephanie McMahon, daughter of the famed Vince McMahon, tweeted in support of Patricia Arquette's speech calling for greater equality for women at the Academy Awards, one of their own wrestlers, AJ Lee, responded by publicly calling Stephanie McMahon out on Twitter for not promoting the women in her own company equally and paying them less than the male stars.

AJ tweet 1

AJ tweet 2

Of course, the women in the company aren't given the same prominence as the men in part because it's felt that they won't make the company as much money. Still, it forced WWE's hand and Stephanie McMahon and the company as a whole publicly embraced the idea of giving the women (who WWE brands as "divas") a chance with the Give Divas A Chance movement (and accompanying trending hashtag).

What's next

The women have been promoted nearly equal to the men in that underground NXT league, but only time will tell if it continues to trickle upward. Wrestlemania didn't seem to show huge promise of that happening, with the one women's match of the show only getting a few minutes in the ring. However, the show also included a high-profile storyline with UFC female fighter and champion Ronda Rousey alongside the Rock, going up against Stephanie McMahon and Triple H, so there appears to be the room for women in prominent positions when they have the right storyline.

Whether WWE is able to wade through these forces of change to make more money — and perhaps regain some of the cultural currency that they've lost since becoming a monopoly and purchasing their top competition in 2001 — remains to be seen. They've stayed relatively steady despite a challenge from UFC, which many see as being what pro wrestling would be like if WWE didn't present fictional  They'll have to hope that giving new stars, including "divas," a chance will take them to another level.

This content is from Southern California Public Radio. View the original story at SCPR.org.




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Aryza expands partnership with GoCardless to enhance payment solutions

Aryza Group has expanded its partnership with



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Getting from Los Angeles to San Francisco in 30 minutes

Business Update with Mark Lacter

Yesterday, we heard about the hyper-loop, a system that could get you from L.A. to San Francisco in about 30 minutes without losing your eyeballs.

Steve Julian: Business analyst Mark Lacter, that might come in handy given how crowded California's air corridor has become...

Mark Lacter: We'll talk about the hyper-loop in a moment, Steve, but yes, the L.A.-to-San Francisco air route is the busiest in the U.S., and it's already the most competitive.  We're talking about more than 50 flights a day, which - if you spread them out between six in the morning and 10:30 at night - there'd be one flight every 20 minutes.  But, Delta obviously thinks there's room for more because it's announced an hourly shuttle between the two cities.  That's another 14 daily flights beginning September 3.  The airline will be using a somewhat smaller jet, and it sounds as if the focus will be on the business traveler, with free newspapers, wine, and beer.

Julian: How much will it cost, do we know?

Lacter: As usual, it's a lot cheaper if you make an advance purchase, but if you're buying your tickets at the last minute - which is what a lot of business travelers do - roundtrip runs a hefty $430.  Actually, this Bay Area shuttle is just the latest effort by Delta to expand out of LAX, which is different from other major airports in that it doesn't have any one airline that dominates (United has a slight edge in market share over American, with Delta about three percentage points behind).  American also has been adding flights out of LAX.

Julian: Sounds like the airline business is improving...

Lacter: That's what happens when you pack planes to the absolute max, which is bad news for travelers being crammed into coach seats.  But it's good news for LAX, which continues to be the airport of choice among airlines looking to add service - matter of fact, domestic passenger traffic was up almost 8 percent in June compared with a year earlier.  Some of those gains might be at the expense of service elsewhere - most especially Ontario Airport, which has seen a big exodus among airlines and passengers.  Ontario city officials have been trying to regain control of the airport, which has been operated by the city of Los Angeles.

Julian: Back to the hyper-loop - is this kind of transport possible?

Lacter: Well, it's the brainchild of billionaire Elon Musk, and you never say never with this guy.  He started the electric car company Tesla and the private space company Space X.  The hyper-loop is a high-speed system of passenger pods that would travel on a cushion of air (think of air hockey table).  The pods would travel at more than 700 miles per hour, but they wouldn't result in sonic booms that severely restricted the Concorde aircraft.  Of course, anything that promises super-speed travel is bound to get people talking - and, from what the physics professors are saying, the Musk idea seems feasible.

Julian: How would its cost compare to the bullet train?

Lacter: He says a lot cheaper.  The price tag on the train is $70 billion at last check; Musk says he can do his for $6 billion.  But, the issue isn't so much the cost or even the technology, but the politics.  As a rule, governments do not think outside the box, and that's what a project like this is all about.  Already, you have bullet train supporters saying that the hyper-loop is impossible, but what they're really saying is we have a lot riding on the train, and we don't want this guy to mess it up.

Julian: But, how much demand is there for high-speed transport?

Lacter: You'd think there would be a lot, but when Boeing came up with a nifty idea for a souped-up plane that would shave almost an hour from L.A. to New York, the airlines said no because it would require more fuel - and that would mean raising fares.  Musk says his system would be a lot cheaper than traveling by plane, which could be a game changer in the attitudes about going places.  But, those attitudes won't change until the thing is actually built, and that can't realistically happen until attitudes change.  That's the ultimate problem.

Julian: Hence, why we're content to squeeze into coach.

Lacter: Yep.

Mark Lacter is a contributing writer for Los Angeles Magazine and writes the business blog at LA Observed.com.

This content is from Southern California Public Radio. View the original story at SCPR.org.




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The RNC in Tampa is closing out

Larry Mantle interviews Tom Brokaw at the 2012 Republican National Convention.; Credit: Lauren Osen/KPCC

Larry Mantle

Our trip to the RNC in Tampa is coming to a close, but we’ve spent time with so many interesting people that our memories will stay strong.  We hope you’ve enjoyed the photos, tweets, and blog postings that have expanded our coverage beyond what we provide live on the air two hours a day.

This is the first political convention where KPCC has used multiple ways of bringing you here without time off from work or having to take a plane ride.  There are many great stories to tell and people to share.  We trust our photos give you a more complete sense of how much goes on at a massive convention like this.

For KPCC journalists, it’s particularly exciting to interact with you in these new ways.  We welcome your tweets and retweets (@AirTalk), comments on our blog postings (www.kpcc.org/blogs/politics), and feedback on our “AirTalk” segment pages. 

All this helps create a real-time way to connect listeners and users of social media in one big conversation.  We hope you enjoy taking part in the convention with us, as much we enjoy sharing it with you.

This content is from Southern California Public Radio. View the original story at SCPR.org.




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The challenges of debate moderating have grown along with partisan differences

US President Barack Obama and Republican Presidential nominee Mitt Romney debate on October 16, 2012 at Hofstra University in Hempstead, New York. Undecided voters asked questions during a town hall format.; Credit: STAN HONDA/AFP/Getty Images

Larry Mantle

There continue to be questions about how moderators approach Presidential debates and about whether the extra time President Obama has received in the first two debates indicates moderator bias in his favor. 

I had chalked up the concerns to Republican hyper-partisanship, such as we saw with many Democrats criticizing Jim Lehrer for his moderating — as though Obama would’ve won the first debate if only Lehrer had asserted himself more.   However, even CNN has been doing significant follow-up on its own Candy Crowley’s performance in debate number two. 

Maybe it’s not just hardcore GOP loyalists who are questioning Crowley’s decision-making on when to cut in and when to allow the candidates to take more time. I thought she did pretty well, but there are plenty of critics.

As someone who has moderated hundreds of debates, I thought I’d share my thoughts on what we’ve seen so far in this election. Though I’ve never moderated a Presidential debate, with its incredible level of attention, concern about rules, and demands by campaigns, there are certain fundamentals regardless of the office or issue at stake.

Time Doesn't Matter...Too Much
First, as strange as this may sound, the time taken by each candidate has little to do with who has an advantage.   Yes, it’s always possible for a candidate to use another minute to fire off the defining line of the night. However, the well-practiced zingers or essential policy explainers are not left to the end of a candidate’s statement, as the clock is running out. 

I’m sure Mitt Romney wasn’t thinking after the last debate, “If only I would’ve had that extra 90-seconds, and Obama hadn’t gotten 90 more than he deserved.”  Both men front-loaded their major talking points and were going to get them in. Neither man could legitimately say he didn’t have a chance to make his strongest points. At some point, a time advantage could make a difference in who wins or loses, but an extra 90-seconds in a debate longer than 90-minutes isn’t going to do it.

Serving The Audience
As a moderator, you also have to think about what best serves your audience. I never guarantee candidates equal time, as it’s my job to serve the listeners, not their campaigns. I strive to get close to equal time, but can’t make any guarantee. Some speakers get to the point succinctly and have their points well put together. Others are messier in their arguments and eat up time just building up any head of steam. 

If the moderator holds to a strict time limit, you run the risk of frustrating listeners by cutting off the rambler just as the candidate is getting to the point. There are methods a moderator can use to help guide the speaker toward being more succinct, but there’s no guarantee the person will be able to comply.

Isn’t this inherently unfair to the succinct speaker? No. The purpose of the debate is to allow the ideas to compete.  It’s not a boxing match that’s about landing punches in a given time. The succinct debater has a big advantage, regardless of how much time the candidate has. That’s why Mitt Romney’s victory in the first debate was so lopsided — he won on the conciseness and clarity of his answers, coupled with Obama’s inability to get to his central points.  Obviously, there are those who thought Obama’s arguments were still more compelling than Romney’s, and that Romney lacked essential details.  However, for most viewers of the first debate, it was stylistically no contest.

Equal Time Is Not A Guarantee
When candidates are allowed to talk to each other directly, it’s very difficult to assure equal time. Even CNN’s clock that registers elapsed time for each candidate is subject to squishiness. Unless a debate is extremely formal, with carefully controlled time limits and a ban on candidates following-up with each other, you’re only going to have an approximation of time balance. I thought Crowley did pretty well to land the second debate with the balance she did. I’m not sure I could get it that close for a debate of that length. She had the added challenge of trying to determine when to cut in on President Obama’s lengthier answers. Also, Romney’s speaking rhythm allows more space for interruption. It’s tougher to break in on Obama.

Moderating Is A Balancing Act
Moderators are always trying to balance a need to move on to the next topic with allowing a candidate to answer an opponent’s charge. Sometimes, you open that door for a candidate, only to regret it later when the politician starts into a monologue, instead of confining the response to the previous challenge. Sometimes moderators, having gotten burned, will become less tolerant of such expansive rebuttals, as the debate goes on. Moderators are always juggling competing goals, and it’s a difficult job (at least for me).

Unfortunately, there are those who think debate moderators attempt to influence the outcome of the debate and the performances of the candidates. Maybe I’m naïve, but I can’t imagine any journalist who’s worked hard enough to get to the position of Presidential debate moderator subordinating his or her career in an effort to getting someone elected. Mainstream political journalism is like national sports reporting. You really don’t care who wins the Super Bowl, you want great story lines to explore with your audience. Yes, sports reporters have affinities for the hometown teams of their youth, but that can’t compete with the professional goal of covering great stories. 

Yes, most journalists in mainstream media probably have a stronger cultural and political affinity for Obama, as he’s more like them. However, it doesn’t mean a journalist is going to sacrifice the better story to intentionally provide a benefit to the President.

 

This content is from Southern California Public Radio. View the original story at SCPR.org.




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THE MARCH FOR SCIENCE AS SEEN FROM HOME

The Loh Life

In case you missed the March for Science, last month?  I have the report!  Not that I went, no. Science enthusiasts all, my household was planning on going—  But then my younger teen daughter got felled by "bacteria"—  Possibly brought on by a dubious "pizza day" at her science magnet.

So I spent that Saturday at home, taking care of her— But we streamed the Washington DC and other marches, live on CNN!  So here is my report!

Let's quickly review the main points.  Worldwide, there were 600-plus cities participating, with high levels of enthusiasm.  The March for Science's stated mission was to be a positive, non-partisan march for scientists and scientific principles.  That alone is such a wonderful, counterintuitive idea.  Much humor and wit was seen.

As I did not get to go, and make my own hilarious sign—?  To honor the spirit of the occasion I would like to share two favorite jokes.

First: How do you tell the difference between an introverted and an extroverted mathematician? 
For the whole time the introverted mathematician is talking to you, he looks down at his shoes.  When the extroverted mathematician talks to you, the whole time he looks down at your shoes.  Ba-dum-bum.

I know I used the pronoun "he" in that joke—  As if to imply all left-brained people are male.  But no!  So here's the saying from when I attended Caltech—  Way back in the '80s—  And the male to female ratio was 7 to 1.  "Caltech: where the odds are good, but the good are odd."

Now to some of the funny—and sometimes punny—March for Science signs:

"If you're not the solution, you're the precipitate!"

That was next to: "Protest Cosine, Protest Sine."  Get it?  Protest. . . Sine?  Puns are hard on the radio.  So let's finish with the more "meta": "What do we want?  Evidence based research!  When do we want it?  After peer review!"  

Of course, there were less than non-partisan messages, too.  Just reporting here?  There were signs with the phrases "Black Hole" and "Absolute Zero" ghosted over our president's recognizeable silhouette.  The live feed from San Francisco brought: "Trump believes there's no global warming, as nothing is hotter than Ivanka."

That one made me snort, but I had to quickly tell my daughter, "that is totally inappropriate."
We decided a good sign was: "Mitosis, Not Division."

And a cute one on a dog that everyone can agree on.  "Support Labs."  Labs. 

Next week: Science is Love!

This content is from Southern California Public Radio. View the original story at SCPR.org.




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THE MARCH FOR SCIENCE AS SEEN FROM HOME

The Loh Life

 
So, my 15 year old science magnet daughter and I experienced last month's exciting March for Science—!  From home, as she was temporarily felled by some bacteria.  Consuming an unscientific "cure" of chocolate pudding—?  We watched the march on CNN.

Now, the news changes so quickly you may not remember that just one month ago—?  There were shock waves due to proposed massive federal budget cuts—  Not just to climate change research, but to—surely the more non-controversial —National Institutes of Health.  I mean, health?  Who's anti-health?  Even MacDonald's is serving apple slices now, and kale!

The march was a mix of passion and fun. There were lots of great signs, including one with the classic line: If you're not the solution, you're the precipitate! Marchers came dressed as Einstein, dinosaurs, polar bears.

Then again—  And admittedly, at home, we were wearing bathrobes rather than labcoats—? A couple of humble notes.

 Some of the speakers in DC were less scientists than YouTube science explainers.  And pure research scientists—not to mention philosophers—might question some of the applause lines.  And I quote: "Science is inherently political!"  "Science is objective, but it is not neutral!"  What?  Then some of the marchers chanted back, with a decided New Age lilt: "Science is hope!"  "Science is our planet!"  "Peace, love, science!"  

I heard myself grousing to my daughter: "Sure.  It's like 'Nature.'  To some, 'Nature' is a beautiful flower.  But 'Nature' is also Stage 5 hurricanes and poison frogs who eat their own offspring.  And—and pitcher plants!  Have you seen pitcher plants?" 

The chants continued:  "Health is science!  Safety is science!  Clean water is science!  I yell at the TV: "PS: Nuclear missiles from North Korea?  SCIENCE!"

There were also heartfelt pleas from the stage for more "K-12 hands-on STEM-based learning."  I sympathize. I marched for that when my daughters were in elementary school.  Of course we want our children to be turned on to science—  To the classroom volcanos comically exploding with baking soda. To the wonders of milk carton pea plants, sunny farms of ladybugs.

But eventually, inexorably, comes The Ugly.  The multiplication tables, long division, algebra, trig, then calculus, if a career in science is really being pursued.  I just heard about a senior I know, an exceptional—and well-rounded—student.  He has a 4.5 GPA and almost-perfect SAT's, nosebleed-high!  But he has been shut out by all the UC's he applied to, including his third choice, UC San Diego.  Mwah!  SCIENCE!

Still, quibbles aside, science is the future.  We applaud all, and must forge on. Chocolate pudding recommended.

This content is from Southern California Public Radio. View the original story at SCPR.org.




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Big Picture Science

Tiny arthropods that live in the pores of our faces




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The Loh Down on Science

City bacteria versus country bacteria when it comes to drugs




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Financing Milestone Paves Way for Next Phase in Gold Project Development

Source: Streetwise Reports 11/12/2024

NexGold Mining Corp. (NEXG.V:TSXV; NXGCF:OTCQX; TRC1.F:FRA)and Signal Gold Inc. have successfully closed their previously announced oversubscribed and upsized concurrent financing. Read more as NexGolds acquisition of Signal Gold sets the stage for near-term production with combined resources and capital driving project development.

NexGold Mining Corp. (NEXG.V:TSXV; NXGCF:OTCQX; TRC1.F:FRA) and Signal Gold Inc. have successfully closed their previously announced oversubscribed and upsized concurrent financing, generating a total of US$18.5 million. Initially disclosed in joint announcements from both companies on October 10 and October 23, 2024, this financing is part of a larger plan in which NexGold will acquire all shares of Signal Gold to combine both companies' gold projects to create a near-term gold developer.

The financing involved two components. The first was a flow-through (FT) unit private placement by NexGold, which raised CA$8.085 million through the sale of 10,106,250 FT units at CA$0.80 per unit. Each unit includes one flow-through common share and half of one purchase warrant, allowing the holder to buy an additional non-flow-through share at CA$1.05 for the next two years. In the second component, Signal Gold's private placement of subscription receipts yielded CA$10.45 million by issuing 120,075,840 receipts at CA$0.08705 each. These receipts will convert into Signal units once specific escrow release conditions are met, including completion of the acquisition. Each unit consists of one common share and half a purchase warrant, allowing the holder to acquire additional shares for CA$0.11818 over two years.

The net funds from this financing will be used to retire debt, fund the exploration and development of both companies' gold projects - including NexGold's Goliath gold complex in Ontario and Signal's Goldboro project in Nova Scotia - and for general corporate purposes. The gross proceeds from FT units will go toward qualified exploration expenses for NexGold's projects, with renunciation planned by December 31, 2024, as per Canadian tax requirements.

Investor interest included an acquisition by a Sprott Asset Management sub-advised fund, which purchased 2.5 million FT units for CA$2 million, bringing Sprott's holdings to 11.43% of NexGold's issued shares (14.95% on a partially diluted basis). NexGold also extended an investor awareness agreement with i2i Marketing Group, providing up to six months of marketing services for CA$250,000 to increase investor visibility.

Gold Rush

Gold's surge to the US$2,800 mark due to a "perfect storm" of factors, according to an October 29 report from Kitco. Gary Wagner explained that this historic rise, approximately 35% this year, was driven by geopolitical tensions, anticipated Federal Reserve rate cuts, consistent central bank demand, and U.S. political uncertainty in the run-up to the presidential election.

Chen Lin offered a positive outlook on NexGold, noting heightened investor interest following recent updates, including expanded financing and merger plans.

Wagner noted that "geopolitical, political conflicts" and "uncertainties about the outcome of the upcoming presidential election" were critical components, with emerging market central banks increasing their gold reserves to reduce reliance on the U.S. dollar.

On October 30, LiveMint highlighted gold's global appeal. The article mentioned how central banks continue to expand their gold reserves, with net buying reaching 337 tonnes in Q3 2023.

This marks a near-record level, according to the World Gold Council. Escalating geopolitical tensions, especially in the Middle East, have also led investors to seek gold as a safe haven, pushing prices upward. In addition, strong economic data in the U.S., such as job growth and consumer spending, has affected expectations around Federal Reserve policies. These, in turn, have indirectly influenced gold.

By November 4, Egon von Greyerz, in his analysis of the global financial system, emphasized gold as a reliable store of value. He argued that "gold has always stood as a protector" during economic downturns, describing the asset as "the best-performing asset class in this century." Von Greyerz asserted that gold's continued strength could be attributed to its resistance to the "destruction of fiat money," making it an essential wealth-preserving asset in an increasingly unstable financial environment.

The Catalysts Pushing NexGold Forward

NexGold's acquisition of Signal Gold is expected to accelerate its growth as a mid-tier gold producer. According to NexGold's September 2024 investor presentation, this financing supports the ongoing development of the Goliath Gold Complex in Northern Ontario, which holds a combined measured and indicated gold resource of over 2.1 million ounces. Additionally, Signal's Goldboro project in Nova Scotia adds strategic value with historical production potential and significant exploration upside.

The Goliath project benefits from robust infrastructure, an approved environmental assessment, and a promising pre-feasibility study indicating a post-tax NPV of CA$336 million at US$1,750/oz gold. With this acquisition, the combined entity is expected to leverage its enhanced capital position to pursue further exploration and optimization, aiming for near-term production and establishing a solid platform for growth and consolidation in the Canadian gold sector.

What Are Experts Saying?

Ron Stewart, a mining analyst at Red Cloud Securities, maintained a Speculative Buy rating on NexGold with a target currently Under Review in his September analysis. Stewart stated that the merger with Signal Gold offered NexGold an accretive pathway to growth by adding the Goldboro project's resources to its portfolio. He noted that the combined assets of NexGold and Signal would form a "multi-asset company with over 6 million ounces in gold resources," which he described as synergistic and favorable for shareholders. Stewart anticipated the merger would close in Q4 2024, with upcoming catalysts including the Goliath Feasibility Study in Q1 2025 and a potential construction decision for Goliath in H2 2025. [OWNERSHIP_CHART-1961]

In the October 24 edition of What is Chen Buying? What is Chen Selling? Chen Lin offered a positive outlook on NexGold, noting heightened investor interest following recent updates, including expanded financing and merger plans. Lin's analysis aligned with Stewart's views on the company's growth potential, highlighting that, with the combined projects and new funding, NexGold is well-positioned for substantial operational growth and asset value expansion in the years ahead.

Ownership and Share Structure

The company notes management and insiders own 3.4% of NexGold.

Institutions own 17%.

Strategic investors own 37.4%. Frank Guistra owns 10.1%. On a partially diluted basis, Sprott owns 14.95%. Extract owns 14%. First Mining owns 4.3%. Matrix owns 1.9%, and Teck own 1.9%.

NexGold has 76 million shares and a market cap of CA$57.16 million.

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Important Disclosures:

  1. NexGold Mining Corp. is a billboard sponsor of Streetwise Reports and pays SWR a monthly sponsorship fee between US$4,000 and US$5,000.
  2. As of the date of this article, officers and/or employees of Streetwise Reports LLC (including members of their household) own securities of NexGold Mining Inc.
  3. James Guttman wrote this article for Streetwise Reports LLC and provides services to Streetwise Reports as an employee.
  4. This article does not constitute investment advice and is not a solicitation for any investment. Streetwise Reports does not render general or specific investment advice and the information on Streetwise Reports should not be considered a recommendation to buy or sell any security. Each reader is encouraged to consult with his or her personal financial adviser and perform their own comprehensive investment research. By opening this page, each reader accepts and agrees to Streetwise Reports' terms of use and full legal disclaimer. Streetwise Reports does not endorse or recommend the business, products, services or securities of any company.

For additional disclosures, please click here.

( Companies Mentioned: NEXG.V:TSXV; NXGCF:OTCQX; TRC1.F:FRA, )




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Fair Value on Metals Explorer Increased by Research Firm

Source: Sid Rajeev 11/12/2024

It is expected that this company significantly will expand the existing resource at its gold-silver project in Nevada, noted a Fundamental Research Corp. report.

Western Exploration Inc. (WEX:TSX.V; WEXPF:OTC) had its fair value increased by Fundamental Research Corp. (FRC) to CA$2.67 per share from CA$2.07 on anticipation of a material resource expansion at the Aura gold-silver project in Nevada, FRC Head of Research Sid Rajeev reported in an Oct. 31 research note.

"[The company] has made notable strides at its Aura gold-silver project, showcasing promising drill results, and improved recoveries," Rajeev wrote. "With mergers and acquisitions (M&A) activity on the rise, we believe Western Exploration Inc. is emerging as a strong acquisition target."

At the time of the report, the explorer was priced at CA$1.24 per share. As such, the new fair value implies a potential return for investors of 115%.

Western Exploration remains a Buy.

Current Project Highlights

Rajeev provided a current overview of the Aura project, noting the company has made significant progress there since FRC's last report, in January.

This Nevada property hosts sediment-hosted, Carlin-style gold deposits. Three have been identified there to date: Doby George, Gravel Creek, and Wood Gulch.

Doby George hosts near-surface, high-grade oxide gold, and mineralization amenable to heap-leach processing, thereby having the potential for relatively low capex and opex. Recent metallurgical heap-leach tests at Doby George yielded a higher gold recovery rate of 72%, up from 69%. This is on the higher end of recoveries for a typical open-pit mine.

Gravel Creek, in contrast, hosts underground, high-grade sulfide gold mineralization. Initial results from an ongoing resource expansion drill program there have been "highly promising," wrote Rajeev. Intercepts have returned unusually high grades, up to 75 grams per ton (75 g/t) gold and 3,080 g/t silver. Assay results from drill hole WGC459 indicate that high-grade mineralization extends at least 80 meters north of the Discovery zone. Preliminary metallurgical test results from Gravel Creek showed "impressive recoveries of 95%" toward the upper end of the usual range for an underground operation.

Resource Expansion Potential

The current aggregated resource of all three deposits is 652,000 ounces of gold equivalent (652 Koz of Au eq) in the Indicated category and 665 Koz Au eq in the Inferred category.

"We believe there is potential for resource expansion as the deposits remain open in multiple directions," Rajeev wrote. He noted which areas remain prospective, and they are Wood Gulch, Gravel Creek, The Gap (the undrilled area between them), the Jarbidge Hanging Wall (without a resource), and the Northeast Extension (undrilled).

Catalysts To Watch For

Rajeev noted future events that could boost Western Exploration's share price. Results of ongoing drilling at Aura is one. Next year, an update to the Gravel Creek and Doby George resource is expected in H1/25. A preliminary feasibility study for Doby George is slated to follow in Q4/25.

Another catalyst is the gold sector, the outlook for which is favorable. M&A activity has picked up as majors are looking for projects to boost their production profile. The trend is positive for this company advancing its precious metals project.

"We maintain a positive outlook on gold in light of the anticipated rate cuts by the U.S. Federal Reserve and elevated geopolitical tensions," the analyst wrote. "We see [Western Exploration] as a prime acquisition target."

Sign up for our FREE newsletter at: www.streetwisereports.com/get-news

Important Disclosures:

  1. Western Exploration Inc. is a billboard sponsor of Streetwise Reports and pays SWR a monthly sponsorship fee between US$4,000 and US$5,000.
  2. As of the date of this article, officers and/or employees of Streetwise Reports LLC (including members of their household) own securities of Western Exploration Inc.
  3. Doresa Banning wrote this article for Streetwise Reports LLC and provides services to Streetwise Reports as an independent contractor.
  4. This article does not constitute investment advice and is not a solicitation for any investment. Streetwise Reports does not render general or specific investment advice and the information on Streetwise Reports should not be considered a recommendation to buy or sell any security. Each reader is encouraged to consult with his or her personal financial adviser and perform their own comprehensive investment research. By opening this page, each reader accepts and agrees to Streetwise Reports' terms of use and full legal disclaimer. Streetwise Reports does not endorse or recommend the business, products, services or securities of any company.

For additional disclosures, please click here.

Disclosures for Fundamental Research Corp., Western Exploration Inc., October 31, 2024

Disclaimers and Disclosure The opinions expressed in this report are the true opinions of the analyst about this company and industry. Any “forward looking statements” are our best estimates and opinions based upon information that is publicly available and that we believe to be correct, but we have not independently verified with respect to truth or correctness. There is no guarantee that our forecasts will materialize. Actual results will likely vary. The analyst and Fundamental Research Corp. “FRC” does not own any shares of the subject company, does not make a market or offer shares for sale of the subject company, and does not have any investment banking business with the subject company. Fees were paid by WEX to FRC. The purpose of the fee is to subsidize the high costs of research and monitoring. FRC takes steps to ensure independence including setting fees in advance and utilizing analysts who must abide by CFA Institute Code of Ethics and Standards of Professional Conduct. Additionally, analysts may not trade in any security under coverage. Our full editorial control of all research, timing of release of the reports, and release of liability for negative reports are protected contractually. To further ensure independence, WEX has agreed to a minimum coverage term including an initial report and three updates. Coverage cannot be unilaterally terminated. Distribution procedure: our reports are distributed first to our web-based subscribers on the date shown on this report then made available to delayed access users through various other channels for a limited time. The distribution of FRC’s ratings are as follows: BUY (67%), HOLD (3%), SELL / SUSPEND (30%). To subscribe for real-time access to research, visit https://www.researchfrc.com/website/subscribe/ for subscription options.

This report contains "forward looking" statements. Forward-looking statements regarding the Company and/or stock’s performance inherently involve risks and uncertainties that could cause actual results to differ from such forward-looking statements. Factors that would cause or contribute to such differences include, but are not limited to, continued acceptance of the Company's products/services in the marketplace; acceptance in the marketplace of the Company's new product lines/services; competitive factors; new product/service introductions by others; technological changes; dependence on suppliers; systematic market risks and other risks discussed in the Company's periodic report filings, including interim reports, annual reports, and annual information forms filed with the various securities regulators. By making these forward-looking statements, Fundamental Research Corp. and the analyst/author of this report undertakes no obligation to update these statements for revisions or changes after the date of this report. A report initiating coverage will most often be updated quarterly while a report issuing a rating may have no further or less frequent updates because the subject company is likely to be in earlier stages where nothing material may occur quarter to quarter. Fundamental Research Corp DOES NOT MAKE ANY WARRANTIES, EXPRESSED OR IMPLIED, AS TO RESULTS TO BE OBTAINED FROM USING THIS INFORMATION AND MAKES NO EXPRESS OR IMPLIED WARRANTIES OR FITNESS FOR A PARTICULAR USE. ANYONE USING THIS REPORT ASSUMES FULL RESPONSIBILITY FOR WHATEVER RESULTS THEY OBTAIN FROM WHATEVER USE THE INFORMATION WAS PUT TO. ALWAYS TALK TO YOUR FINANCIAL ADVISOR BEFORE YOU INVEST. WHETHER A STOCK SHOULD BE INCLUDED IN A PORTFOLIO DEPENDS ON ONE’S RISK TOLERANCE, OBJECTIVES, SITUATION, RETURN ON OTHER ASSETS, ETC. ONLY YOUR INVESTMENT ADVISOR WHO KNOWS YOUR UNIQUE CIRCUMSTANCES CAN MAKE A PROPER RECOMMENDATION AS TO THE MERIT OF ANY PARTICULAR SECURITY FOR INCLUSION IN YOUR PORTFOLIO. This REPORT is solely for informative purposes and is not a solicitation or an offer to buy or sell any security. It is not intended as being a complete description of the company, industry, securities or developments referred to in the material. Any forecasts contained in this report were independently prepared unless otherwise stated and HAVE NOT BEEN endorsed by the Management of the company which is the subject of this report. Additional information is available upon request. THIS REPORT IS COPYRIGHT. YOU MAY NOT REDISTRIBUTE THIS REPORT WITHOUT OUR PERMISSION. Please give proper credit, including citing Fundamental Research Corp and/or the analyst, when quoting information from this report. The information contained in this report is intended to be viewed only in jurisdictions where it may be legally viewed and is not intended for use by any person or entity in any jurisdiction where such use would be contrary to local regulations or which would require any registration requirement within such jurisdiction.

( Companies Mentioned: WEX:TSX.V;WEXPF:OTC, )




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SmartBank secures USD 26 million for its personal finance management app

Japan-based startup SmartBank has announced the rise of a USD 26 million funding round, aimed at the development of its personal finance management app. 




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Alchemy Pay obtains 4 new Money Transmitter Licences

Crypto payment gateway Alchemy Pay has acquired Money Transmitter Licences (MTLs) in Minnesota, Oklahoma, Oregon, and Wyoming.




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With signing of insurance bill, Lyft, Uber ridesharing loophole comes to an end

AB 2293 bans drivers from using their personal policies and mandates that drivers have to be covered from the moment they turn on their app and look for customers.; Credit: Photo by Daniel X. O'Neil via Flickr Creative Commons

Amid all the talk about cutting-edge technology, much of Uber and Lyft’s success actually owes to that fact the ride-sharing companies have been able to exploit a basic loophole: The companies foist the cost of insurance on their drivers, but the drivers' insurance companies don’t know they are underwriting cars for hire, and even if drivers wanted to be honest and get a policy that would cover ride-sharing, they couldn’t, because no such policy exists.

AB-2293, introduced by Assemblywoman Susan Bonilla (D-Concord) and signed into law Wednesday by Governor Jerry Brown, tries to close the loophole by paving the way for insurance companies to offer hybrid personal/commercial policies by next summer.

Uber once derided the bill as a backroom deal between insurance companies and trial lawyers.

"The bill does nothing to enhance safety, yet compromises the transportation choices and entrepreneurial opportunities Uber offers Californians," the company wrote in a June blog post that encouraged customers to contact their representatives opposing the bill.

However, the company backed down and supported the legislation when Bonilla insurance requirements were lowered.

AB 2293 also specifically bans drivers from using their personal policies and mandates drivers have to be covered from the moment they turn on their app and look for customers, which is a response to the tragic accident on New Year's Eve in San Francisco when an UberX driver hit and killed a six year old child.

Uber argued that because the driver was waiting for a fare he wasn't working for the company at the time, so he wasn't covered by the company's insurance.




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Warner Brothers job cuts determined by financial target

We reported last week that layoffs were coming soon to Warner Brothers, but how many positions will be cut is still unknown.  

A spokesman for Warner Brothers Entertainment, Paul McGuire, told KPCC there's no exact number yet. "There is no headcount reduction target, but there is a substantial financial target," Maguire said. 

“This is a budget issue, not a head count issue,” Dee Dee Myers, Warner Brothers Vice President of Corporation Communications told Variety.  The trade publication reports that Warner Brothers is expected to eliminate as many as 1,000 positions worldwide - or about 10 percent of its workforce:

Senior managers are currently assessing their businesses to come up with ways to trim overhead. Only at the end of that process will an exact reduction figure be known. It could be somewhat lower than the current numbers being speculated, but cuts are expected to be substantial.  

News of coming layoffs became public two weeks ago, when KPCC and other media outlets obtained an internal memo written by Warner Bros. Chairman and Chief Executive Officer Kevin Tsujihara.   

"It pains me to say this, positions will be eliminated—at every level—across the Studio," Tsujihara wrote in the memo. 

Morningstar Analyst Neil Macker told KPCC that management at Warner Brothers is trying to protect the company from another takeover play by Rupert Murdoch.  In July, Murdoch offered to buy parent company Time Warner for $80 billion. He withdrew the offer in August. 

 




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Bharat Panchal takes charge as Chief Risk, Security, and Stakeholder Management Officer, Bima Sugam India Federation

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Indonesia's Indosat, GoTo launch local language AI model

Sahabat-AI would enable Indonesians to build artificial intelligence-based services and applications in Bahasa Indonesia and various other local languages, with the understanding of local context, the companies said in a joint statement.




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Rapidojet from Bakery Concepts International, LLC

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Inclusion Technologies Introduces Nadanut™ Naturals

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SK Food International introduces AncientGrisps

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Campbell announces reorganization plans, management changes

Campbell Soup Co. plans to reorganize its businesses into three divisions, each headed by a president. In addition, Irene Chang Britt, president–Pepperidge Farm and senior vice president–Global Baking and Snacking, will leave the company.




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Snyder’s-Lance introduces new corporate logo

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Snyder's-Lance introduces Clearview Foods Division

The new division will focus on developing innovative snacks and capitalizing on emerging consumer trends.