dead Employers Face June 1, 2024 Deadline to Comply with Lehigh County, Pennsylvania’s New Expansive Anti-Discrimination Ordinance By www.littler.com Published On :: Thu, 02 May 2024 16:48:51 +0000 The Lehigh County Human Relations Ordinance was enacted February 26, 2024, establishing county-specific non-discrimination requirements for employment, housing, education, health care and public accommodations. The ordinance also creates a Lehigh County Human Relations Commission charged with investigating and enforcing claims of discrimination. The ordinance becomes effective June 1, 2024. Expanded Protected Characteristics and Employer Coverage Full Article
dead Inherit the Dead A Novel Lee Child. By library.gcpl.lib.oh.us Published On :: This New York Times and USA TODAY bestseller, is a collaboration between twenty bestselling mystery novelists who have joined forces to create a spellbinding story of love, betrayal, and intrigue. Pericles "Perry" Christo is a PI with a past-a former cop who lost his badge and his family when a corruption scandal left him broke and disgraced. So when wealthy Upper East Side matron Julia Drusilla summons him one cold February night, he grabs what seems to be a straightforward (and lucrative) case. The socialite is looking for her beautiful, aimless daughter, Angelina, who is about to become a very wealthy young woman. But as Christo digs deeper, he discovers there's much more to the lovely "Angel" than meets the eye. This classic noir tale twists and turns down New York's mean streets and along Hamptons' beaches and back roads during a bitterly cold and gray winter where nothing is as it seems and everyone has something to hide. In this inventive "serial novel" storytelling approach, each of the twenty bestselling writers brings his or her distinctive voice to a chapter of Inherit the Dead, building the tension to a shocking, explosive finale. The editor, Jonathan Santlofer, has arranged to donate any royalties in excess of editor and contributor compensation to Safe Horizon, the leading victim assistance agency in the country. Full Article
dead After Dead What Came Next in the World of Sookie Stackhouse Charlaine Harris. By library.gcpl.lib.oh.us Published On :: Find out what happened after the conclusion of the #1 New York Times bestselling Sookie Stackhouse series. Dead Ever After marked the end of the Sookie Stackhouse series-novels that garnered millions of fans and spawned the hit HBO television show True Blood. It also stoked a hunger that will never die...a hunger to know what happened next. With characters arranged alphabetically-from the Ancient Pythoness to Bethany Zanelli-bestselling author Charlaine Harris takes fans into the future of their favorite residents of Bon Temps and environs. You'll learn how Michele and Jason's marriage fared, what happened to Sookie's cousin Hunter, and whether Tara and JB's twins grew up to be solid citizens. This coda provides the answers to your lingering questions-including details of Sookie's own happily-ever-after... Full Article
dead Dead Ever After Charlaine Harris. By library.gcpl.lib.oh.us Published On :: THE FINAL NOVEL IN THE #1 NEW YORK TIMES BESTSELLING SOOKIE STACKHOUSE SERIES! When a shocking murder rocks the small town of Bon Temps, Louisiana, psychic cocktail waitress Sookie Stackhouse learns that she has more than one enemy waiting to get vengeance for the past, because nothing is ever clear-cut in Bon Temps. What passes for truth is only a convenient lie. What passes for justice is more spilled blood. And what passes for love is never enough... Full Article
dead DEADLINE EXTENDED: 2024 CPOD 14th International Symposium and Poster Session (November 13, 2024 9:00am) By events.umich.edu Published On :: Thu, 24 Oct 2024 15:48:41 -0400 Event Begins: Wednesday, November 13, 2024 9:00am Location: Taubman Biomedical Science Research Building Organized By: Center for Cell Plasticity and Organ Design The Center for Cell Plasticity and Organ Design (CPOD) is excited to announce our 14th International Symposium and Poster Session to be held on Wednesday, November 13th at the Biomedical Science Research Building Kahn Auditorium. The Symposium is an all-day event that begins with an international virtual speaker session held during the morning. The remainder of the day is filled with a series of in-person speaker sessions, a poster session and a poster award ceremony, followed by a reception. We invite you to register for this year’s symposium by using our online registration form. The deadline to register is October 28, 2024 by 11:59pm. We also invite you to submit an abstract by using our online abstract submission form. The submission deadline is October 28, 2024 by 11:59pm. All submitted abstracts will be reviewed by the CPOD Poster Session Committee. If selected, each poster will be judged with a poster award ceremony held at the end of the Symposium. Poster presenters will be notified they have been selected by late October. Display space is limited, and we want to hear about your research, so submit your abstract today! For assistance with or questions about registration and abstract submissions, contact us at CPOD-contact@umich.edu. Sign up at CPOD-friends-requests@umich.edu to receive updates from CPOD for updates about the 14th International Symposium and Poster Session and upcoming CPOD seminar events. Full Article Conference / Symposium
dead Living for the Dead By www.npr.org Published On :: Tue, 01 Aug 2023 04:00:32 +0000 There are people who help us at every stage of life –– from the moment we're born to our last breath. But at the end, who's helping us when we're gone? On the season finale of the StoryCorps Podcast, twin mortician brothers look back on a life of caring for the dead.Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy Full Article
dead U of T invites input on call for fossil fuel divestment - Deadline extended to invite further submissions By media.utoronto.ca Published On :: Mon, 15 Jun 2015 13:15:30 +0000 Deadline extended to invite further submissionsToronto, ON – The University of Toronto is inviting members of its community to make submissions to an advisory committee studying a recent call for divestment from fossil fuel companies. The request for submissions is the latest step in the work of the committee examining the divestment issue. The committee may […] Full Article Environment & Natural Resources Media Releases
dead 25 Years of Stories: Seven Deadly Sins By play.prx.org Published On :: Fri, 19 Aug 2022 04:00:00 -0000 This week, we take a look back at a magical Moth live show. This episode is hosted by Sarah Austin Jenness. Host: Sarah Austin Jenness Live Host: Andy Borowitz Storytellers: Zeroboy explores gluttony in audio. Erica Jong gets a meat and fish delivery from an ex. This episode is dedicated to the memory of Katie Sanderson, who ran The Young Lions program in 2006, and later came to work with us at The Moth. Full Article mothshorts
dead Are Job Boards Dead? A Look Into The Future of Recruitment Advertising By www.recruiter.com Published On :: Thu, 11 Jul 2024 17:45:56 EST Last week marked the end of an era, as Monster and CareerBuilder announced they were entering a marriage of equals, more or less undermining most of their sales messaging over the last two decades of this once powerful duopoly. Not so very long ago, of course, such a move would have been unthinkable. Full Article
dead Delayed by Deadly Wastes: A Rented Car Gives Rise to All 8 of Them By www.qualitymag.com Published On :: Thu, 17 Oct 2024 00:00:00 -0400 In a world where every minute matters, a car rental turns into a frustrating ordeal of delays and inefficiencies. Will I reach my important meeting on time, or will I be exposed to the 8 deadly wastes? Full Article
dead Infographic: 6 Deadly Facts About Indoor Air Quality By www.achrnews.com Published On :: Mon, 12 Nov 2018 07:28:00 -0500 While exterior pollutants, such as smog and CO, may receive more attention, IAQ within a home can have serious effects on our physical and mental health, as well. Full Article
dead Xen Security Advisory 463 v2 (CVE-2024-45818) - Deadlock in x86 HVM standard VGA handling By seclists.org Published On :: Tue, 12 Nov 2024 12:11:26 GMT Posted by Xen . org security team on Nov 12 Xen Security Advisory CVE-2024-45818 / XSA-463 version 2 Deadlock in x86 HVM standard VGA handling UPDATES IN VERSION 2 ==================== Public release. ISSUE DESCRIPTION ================= The hypervisor contains code to accelerate VGA memory accesses for HVM guests, when the (virtual) VGA is in "standard" mode. Locking involved there has an unusual discipline, leaving... Full Article
dead Substation Equipment Maintenance: Often Neglected Until Something Big Drops Dead By electrical-engineering-portal.com Published On :: Mon, 13 May 2024 05:49:16 +0000 The aging process starts the moment new substation equipment is put into service; how quickly it happens depends on a number of factors, including the equipment’s use, the environment, the quality of maintenance, and many more. However, things aren’t the... Read more The post Substation Equipment Maintenance: Often Neglected Until Something Big Drops Dead appeared first on EEP - Electrical Engineering Portal. Full Article Maintenance Power Substation Protection Transmission and Distribution circuit breaker circuit breakers condition-based maintenance corrective maintenance electrical equipment high voltage switchgear low voltage switchgear maintenance intervals medium voltage switchgear molded case circuit breakers overcurrent periodic lubrication power circuit breakers predictive maintenance preventative maintenance sf6 gas circuit breakers short-circuit tripping substation substation equipment time-based maintenance
dead Dri-Eaz Beats Refrigerant Ban Deadline By www.randrmagonline.com Published On :: Thu, 14 Mar 2024 13:00:00 -0400 Jan. 1, 2025 sets a new requirement for global-warming-potential refrigerants in California. Full Article
dead It’s Been a Very Busy Week at the PA Capitol as the Budget Deadline Looms By www.pacatholic.org Published On :: Fri, 28 Jun 2024 14:28:53 +0000 There was a lot going on this week at the PA Capitol and work continues to try to get a budget in place by the Sunday deadline. Here are some highlights from the week as posted on our Facebook page. https://www.facebook.com/share/v/1aqPW3tYtMySPUcY/?mibextid=WC7FNe https://www.facebook.com/share/v/iPW4XyHKBf3oNVpA/?mibextid=WC7FNe https://www.facebook.com/share/v/MRTAq999kpMtkhv9/?mibextid=WC7FNe https://www.facebook.com/share/v/7ZdipDQTXzD21sM1/?mibextid=WC7FNe https://www.facebook.com/share/v/HMNCDYPoBPLBkMHn/?mibextid=WC7FNe https://www.facebook.com/share/v/2R5HH7NwBWVfMptZ/?mibextid=WC7FNe https://www.facebook.com/share/v/EhG7jnpXiU6wgbM9/?mibextid=WC7FNe https://www.facebook.com/share/v/ZpTH7M8RmkWASUTD/?mibextid=WC7FNe https://www.facebook.com/share/v/s2DhksEQn8eiyWhR/?mibextid=WC7FNe https://www.facebook.com/share/v/RwnUBVxxYpHCEds3/?mibextid=WC7FNe https://www.facebook.com/share/v/HGy8LvPkMrWfaUSQ/?mibextid=WC7FNe https://www.facebook.com/share/v/GZB94RZN77WXGCkq/?mibextid=WC7FNe https://www.facebook.com/share/v/8dkx16UsiGUsi7y1/?mibextid=WC7FNe Full Article Health Care Homepage Feature Homepage Posts
dead CPGs on Deadline by Amazon to Overhaul Packaging By www.packagingstrategies.com Published On :: Fri, 22 Feb 2019 00:00:00 -0500 Some consumer packaged goods brands have been asked by Amazon in recent months to overhaul their product packaging to be greener, sturdier and cheaper to ship, according to Forbes. Full Article
dead Drug Supply Chain Compliance: AV Group Joins Partnership as DSCSA Deadline Looms By www.packagingstrategies.com Published On :: Tue, 29 Aug 2023 00:00:00 -0400 Antares Vision Group becomes first DSCSA solution provider to join the Pulse Interoperable Partner program of the National Association of Boards of Pharmacy (NABP). Full Article
dead In Surprise Ruling, FCC Denies Request for Extension of FM Booster Stations Comment Deadline By www.nab.org Published On :: 24 May 2022 00:00:00 EST WASHINGTON, D.C. – Today the Federal Communications Commission denied a joint request by NAB and NPR for a two-week extension of the comment deadline in a proceeding on FM broadcast booster stations. The following statement can be attributed to NAB Chief Legal Officer Rick Kaplan: Full Article
dead Traffic Safety News – Don’t Join The Walking Dead By news.delaware.gov Published On :: Mon, 03 Jun 2013 23:39:54 +0000 Don’t Join The Walking Dead. That is the new message OHS along with their traffic safety partners are conveying to pedestrians across Delaware. What you need to know Walking safely is really just about using your brain. When people walk around mindlessly, they get hurt or killed. Out of all the deaths that occur on […] Full Article Traffic Safety News pedestrian safety public safety publicsafety traffic enforcement traffic safety
dead 'Legionella Is Flourishing': GSA Confronts Deadly Bacteria By www.facilitiesnet.com Published On :: Mon, 4 Nov 2024 00:00:00 CST Full Article
dead Marvel Legends Deadpool & Wolverine Action Figures Are Some Of The MCU's Best Collectibles By www.slashfilm.com Published On :: Tue, 12 Nov 2024 13:45:37 +0000 Marvel Legends' new Deadpool & Wolverine action figures are among the best Marvel Cinematic Universe collectibles that Hasbro has released so far. Full Article Reviews Superhero Movies
dead 10 Best Deadpool Quotes In Deadpool & Wolverine By screenrant.com Published On :: Wed, 13 Nov 2024 04:59:15 GMT Deadpool is notorious for his meta-commentary and cutting remarks, many of which are on full display in the MCUs Deadpool & Wolverine. Full Article Movies Marvel Cinematic Universe Deadpool & Wolverine
dead Rust's Sneaky Deadlock With `if let` Blocks By brooksblog.bearblog.dev Published On :: Sat, 09 Nov 2024 10:02:52 +0000 Comments Full Article
dead El curioso pueblo de Málaga rodeado de sierra y mar que se conoce como 'el pequeño Madrid' By www.elmundo.es Published On :: Thu, 07 Nov 2024 17:57:11 +0100 El municipio de la Axarquía está a 45 minutos de la capital y tiene un famoso pasado histórico Leer Full Article Andalucía Málaga TresB LCL
dead Así resistió la 'invicta' Bilbao cinco meses de asedios con la destrucción de 6.500 bombas, sin alimentos rodeada de carlistas By www.elmundo.es Published On :: Mon, 21 Oct 2024 21:39:37 +0200 El arqueólogo Gorka Martín detalla en 'Bilbao, 1874' uno de los episodios de la historia de la capital vizcaína que ha marcado su impronta liberal. El autor presenta mañana martes en la FNAC de Bilbao un asedio clave en la Tercera Guerra Carlista. Leer Full Article Bilbao España Sergio Ramos - MX Xabi Alonso - MX Ola de calor - MX Salomón Chertorivski - MX Felipe Calderón - MX Samuel García - MX Vicente Fox - MX Ricardo Anaya - MX Santiago Taboada - MX Jorge Álvarez Máynez - MX Genaro García Luna - MX Clima - MX Sumar País Vasco Navarra Playas Elecciones Artículos Josean Izarra
dead Iran Deal Deadline Looming By www.cbsnews.com Published On :: Thu, 01 Oct 2015 09:22:20 -0400 Pamela Falk, CBS News Foreign Affairs Analyst, discusses the Iran nuclear talks. Diplomats are struggling to reach an agreement on the deal's framework before their self-imposed deadline. Full Article
dead Congress passes first package of spending bills just hours before shutdown deadline for key agencies By federalnewsnetwork.com Published On :: Sat, 09 Mar 2024 01:11:06 +0000 The Senate on Friday approved a $460 billion package of spending bills in time to meet a midnight deadline for avoiding a shutdown of many key federal agencies, The post Congress passes first package of spending bills just hours before shutdown deadline for key agencies first appeared on Federal News Network. Full Article All News Congress Government Shutdown government funding Senate
dead Biden signs package of spending bills just hours before government shutdown deadline By federalnewsnetwork.com Published On :: Sat, 09 Mar 2024 18:05:59 +0000 President Joe Biden has signed into law a package of spending bills passed by the Senate in time to avoid a partial government shutdown. The post Biden signs package of spending bills just hours before government shutdown deadline first appeared on Federal News Network. Full Article All News Budget Congress Government Shutdown Management
dead DoD agencies confront zero trust challenges, misunderstandings ahead of 2026 deadline By federalnewsnetwork.com Published On :: Wed, 02 Oct 2024 13:08:24 +0000 The Defense Department’s zero trust framework is acting as a catalyst, driving mission owners to industry in search of zero trust solutions The post DoD agencies confront zero trust challenges, misunderstandings ahead of 2026 deadline first appeared on Federal News Network. Full Article All News Big Data Federal Insights IT Modernization Technology AWS SAPNS2
dead $3B VA supplemental passes House, senators urge final vote by Friday deadline By federalnewsnetwork.com Published On :: Wed, 18 Sep 2024 22:06:58 +0000 VA needs the emergency funding by Friday to avoid delays in compensation and pension benefit payments that go to 7 million veterans and their survivors. The post $3B VA supplemental passes House, senators urge final vote by Friday deadline first appeared on Federal News Network. Full Article All News Budget Congress Management Veterans Affairs Workforce Jerry Moran Jon Tester Joshua Jacobs Mike Johnson PACT Act Senate Veterans Affairs Committee Shereef Elnahal Veterans Benefits Administration Veterans Health Administration
dead One dead after tropical storm Trami hits the Philippines By www.euronews.com Published On :: Wed, 23 Oct 2024 17:30:37 +0200 One dead after tropical storm Trami hits the Philippines Full Article
dead Typhoon Kong-rey hits Taiwan's east coast, leaving at least 1 dead By www.euronews.com Published On :: Thu, 31 Oct 2024 18:23:38 +0100 Typhoon Kong-rey hits Taiwan's east coast, leaving at least 1 dead Full Article
dead Survivors sought and village evacuations in wake of deadly Lewotobi volcano eruptions By www.euronews.com Published On :: Tue, 05 Nov 2024 16:00:58 +0100 Survivors sought and village evacuations in wake of deadly Lewotobi volcano eruptions Full Article
dead Violent protests erupt in Serbia after deadly train station canopy collapse By www.euronews.com Published On :: Wed, 06 Nov 2024 11:14:50 +0100 Violent protests erupt in Serbia after deadly train station canopy collapse Full Article
dead A Radio Burst from a Giant "Dead" Galaxy By skyandtelescope.org Published On :: Thu, 07 Nov 2024 13:00:00 +0000 Exotic magnetars make brief, powerful flashes of radio waves — but a new discovery suggests there may be more than one way to make a magnetar. The post A Radio Burst from a Giant "Dead" Galaxy appeared first on Sky & Telescope. Full Article Astronomy & Observing News Stellar Science Fast Radio Bursts
dead Draft bills dead in California but still alive in Congress By hasbrouck.org Published On :: 2024-07-01T15:46:32-08:00 A proposal to automatically register applicants for California driver's licenses with the Selective Service System for a possible military draft was pulled by its author, Sen. Bob Archuleta (D-Pico Rivera), just before a scheduled hearing today in the state Assembly Transportation Committee. This was the last scheduled meeting of that committee before the deadline for consideration of bills in this year's legislative session, so the bill is effectively dead for the year. Like similar laws in other states, California SB-1081 faced opposition from a coalition of peace, civil liberties, and immigrant rights organizations, on both policy and fiscal grounds. Pulling the bill before the hearing today was a face-saving way for Sen. Archuleta to avoid a vote by the committee not to advance his bill to the Assembly floor. This was at least the seventh time that similar proposals in California have been rejected, but the Selective Service System and its California state directors keep finding new sponsors to reintroduce them in the state legislature. Meanwhile, however, an ill-considered proposal to try to automate draft registration introduced at the instigation of the Selective Service System by Rep. Chrissy Houlahan (D-PA) remains under consideration as part of the House version of this year's National Defense [sic] Authorization Act (NDAA), along with a proposal to expand draft registration to include young women as well as young men in the Senate version of the NDAA. There's a chance that both of these proposals for changes to Selective Service registration could be removed during back-room negotiations in the House-Senate conference committee on the NDAA later this year, after the elections. But we've seen this movie before. These bad ideas will be back again next year, regardless of which party wins which federal elections. Preparation for a military draft, and reliance on the perceived availability of a fallback draft as the basis for planning of endless, unlimited, unpopular wars, won't stop until Congress repeals the Military Selective Service Act and ends draft registration entirely, either through a standalone bill like the Selective Service Repeal Act or through a provision in this or a future year's NDAA. Full Article
dead Violence, statistics, and the politics of accounting for the dead By search.lib.uiowa.edu Published On :: Location: Law Library- JC328.6V56 2016 Full Article
dead Weird cosmic object identified as the remains of an exploded dead star By www.avjobs.com Published On :: Fri, 4 Aug 2023 06:38:31 -0400 Weird Cosmic Object Identified As The Remains Of An Exploded Dead Star spacenotebook... Full Article cosmos explosion space galaxy stars
dead Application deadline extended for the World Post & Parcel Awards! By postandparcel.info Published On :: Thu, 29 Feb 2024 13:18:54 +0000 Applications to the World Post & Parcel Awards 2024 are still open! There are 8 awards categories that you can choose to submit an entry for. Full Article E-Commerce Freight Infrastructure Innovation Parcel Post Retail Sustainability
dead The Biology Of Why Coronavirus Is So Deadly By scienceblogs.com Published On :: Thu, 02 Apr 2020 18:02:27 +0000 The Biology Of Why Coronavirus Is So Deadly COVID-19 is caused by a coronavirus called SARS-CoV-2. Coronaviruses belong to a group of viruses that infect animals, from peacocks to whales. They’re named for the bulb-tipped spikes that project from the virus’s surface and give the appearance of a corona surrounding it. A coronavirus infection usually plays out one of two ways: as an infection in the lungs that includes some cases of what people would call the common cold, or as an infection in the gut that causes diarrhea. COVID-19 starts out in the lungs like the common cold coronaviruses, but then causes havoc with the immune system that can lead to long-term lung damage or death. SARS-CoV-2 is genetically very similar to other human respiratory coronaviruses, including SARS-CoV and MERS-CoV. However, the subtle genetic differences translate to significant differences in how readily a coronavirus infects people and how it makes them sick. SARS-CoV-2 virus particles (pink dots) on a dying cell. National Institute of Allergy and Infectious Diseases, NIH SARS-CoV-2 has all the same genetic equipment as the original SARS-CoV, which caused a global outbreak in 2003, but with around 6,000 mutations sprinkled around in the usual places where coronaviruses change. Think whole milk versus skim milk. Compared to other human coronaviruses like MERS-CoV, which emerged in the Middle East in 2012, the new virus has customized versions of the same general equipment for invading cells and copying itself. However, SARS-CoV-2 has a totally different set of genes called accessories, which give this new virus a little advantage in specific situations. For example, MERS has a particular protein that shuts down a cell’s ability to sound the alarm about a viral intruder. SARS-CoV-2 has an unrelated gene with an as-yet unknown function in that position in its genome. Think cow milk versus almond milk. How the virus infects Every coronavirus infection starts with a virus particle, a spherical shell that protects a single long string of genetic material and inserts it into a human cell. The genetic material instructs the cell to make around 30 different parts of the virus, allowing the virus to reproduce. The cells that SARS-CoV-2 prefers to infect have a protein called ACE2 on the outside that is important for regulating blood pressure. The infection begins when the long spike proteins that protrude from the virus particle latch on to the cell’s ACE2 protein. From that point, the spike transforms, unfolding and refolding itself using coiled spring-like parts that start out buried at the core of the spike. The reconfigured spike hooks into the cell and crashes the virus particle and cell together. This forms a channel where the string of viral genetic material can snake its way into the unsuspecting cell. An illustration of the SARS-CoV-2 spike protein shown from the side (left) and top. The protein latches onto human lung cells. 5-HT2AR/Wikimedia SARS-CoV-2 spreads from person to person by close contact. The Shincheonji Church outbreak in South Korea in February provides a good demonstration of how and how quickly SARS-CoV-2 spreads. It seems one or two people with the virus sat face to face very close to uninfected people for several minutes at a time in a crowded room. Within two weeks, several thousand people in the country were infected, and more than half of the infections at that point were attributable to the church. The outbreak got to a fast start because public health authorities were unaware of the potential outbreak and were not testing widely at that stage. Since then, authorities have worked hard and the number of new cases in South Korea has been falling steadily. How the virus makes people sick SARS-CoV-2 grows in type II lung cells, which secrete a soap-like substance that helps air slip deep into the lungs, and in cells lining the throat. As with SARS, most of the damage in COVID-19, the illness caused by the new coronavirus, is caused by the immune system carrying out a scorched earth defense to stop the virus from spreading. Millions of cells from the immune system invade the infected lung tissue and cause massive amounts of damage in the process of cleaning out the virus and any infected cells. Each COVID-19 lesion ranges from the size of a grape to the size of a grapefruit. The challenge for health care workers treating patients is to support the body and keep the blood oxygenated while the lung is repairing itself. How SARS-CoV-2 infects, sickens and kills people SARS-CoV-2 has a sliding scale of severity. Patients under age 10 seem to clear the virus easily, most people under 40 seem to bounce back quickly, but older people suffer from increasingly severe COVID-19. The ACE2 protein that SARS-CoV-2 uses as a door to enter cells is also important for regulating blood pressure, and it does not do its job when the virus gets there first. This is one reason COVID-19 is more severe in people with high blood pressure. SARS-CoV-2 is more severe than seasonal influenza in part because it has many more ways to stop cells from calling out to the immune system for help. For example, one way that cells try to respond to infection is by making interferon, the alarm signaling protein. SARS-CoV-2 blocks this by a combination of camouflage, snipping off protein markers from the cell that serve as distress beacons and finally shredding any anti-viral instructions that the cell makes before they can be used. As a result, COVID-19 can fester for a month, causing a little damage each day, while most people get over a case of the flu in less than a week. At present, the transmission rate of SARS-CoV-2 is a little higher than that of the pandemic 2009 H1N1 influenza virus, but SARS-CoV-2 is at least 10 times as deadly. From the data that is available now, COVID-19 seems a lot like severe acute respiratory syndrome (SARS), though it’s less likely than SARS to be severe. What isn’t known There are still many mysteries about this virus and coronaviruses in general – the nuances of how they cause disease, the way they interact with proteins inside the cell, the structure of the proteins that form new viruses and how some of the basic virus-copying machinery works. Another unknown is how COVID-19 will respond to changes in the seasons. The flu tends to follow cold weather, both in the northern and southern hemispheres. Some other human coronaviruses spread at a low level year-round, but then seem to peak in the spring. But nobody really knows for sure why these viruses vary with the seasons. What is amazing so far in this outbreak is all the good science that has come out so quickly. The research community learned about structures of the virus spike protein and the ACE2 protein with part of the spike protein attached just a little over a month after the genetic sequence became available. I spent my first 20 or so years working on coronaviruses without the benefit of either. This bodes well for better understanding, preventing and treating COVID-19. By Benjamin Neuman, Professor of Biology, Texas A&M University-Texarkana. This article is republished from The Conversation under a Creative Commons license. Read the original article. The Conversation Thu, 04/02/2020 - 14:02 Categories Life Sciences Full Article
dead As bird flu outbreaks rise, piles of dead cattle become shocking Central Valley tableau By www.latimes.com Published On :: Sun, 20 Oct 2024 10:00:44 GMT Although California dairy farmers had heard about the H5N1 bird flu before it hit, none was prepared for the devastation it would cause in some herds. Full Article
dead Off-duty California deputy shot dead by police on golf course By www.washingtonexaminer.com Published On :: Thu, 17 Aug 2023 07:16:48 GMT An off-duty Los Angeles County Sheriff's Department deputy was shot and killed by police at a golf course on Tuesday after he allegedly started shooting his gun following a domestic situation. Full Article
dead LIV-PGA agreement deadline expected to be extended: Report By www.washingtonexaminer.com Published On :: Fri, 29 Dec 2023 20:11:01 GMT A deal between the PGA Tour and LIV Golf is not expected by Dec. 31, but the deadline is expected to be extended as the two entities reportedly appear within sight of making a deal. Full Article
dead How AI might help researchers make esophageal cancer less deadly By www.latimes.com Published On :: Mon, 16 Sep 2024 10:00:29 GMT To improve survival for esophageal cancer patients, researchers are using artificial intelligence to improve screening for the disease. Full Article
dead Fentanyl is flooding into the Inland Northwest, triggering a deadlier phase of the opioid crisis By www.inlander.com Published On :: Thu, 30 Sep 2021 01:40:00 -0700 Allan didn't know it was fentanyl… Full Article News/Local News
dead One month behind the scenes of Spokane's ongoing fight to end the deadly fentanyl crisis By www.inlander.com Published On :: Thu, 07 Nov 2024 01:30:00 -0800 In Spokane County, a single person died of a fentanyl-related overdose in 2018, according to official records… Full Article News/Local News
dead Hugh Jackman Enlists NY Cop to Pressure Ryan Reynolds Into Getting Him in 'Deadpool 3' By www.aceshowbiz.com Published On :: Mon, 03 May 2021 08:14:14 +0000 In a video posted on his social media accounts, an officer named John Dobkowski tells the 'Deadpool' star to get the 'Logan' actor in the upcoming movie, or else he will be ticketing Reynolds. Full Article movie Deadpool 3 Hugh Jackman;Ryan Reynolds
dead Zack Snyder Spills on Removal of Zombie Stripper From 'Army of the Dead' By www.aceshowbiz.com Published On :: Tue, 04 May 2021 04:21:06 +0000 Less than two weeks before his heist thriller hits select theaters, the 'Zack Snyder's Justice League' director also stresses that any references to the global health crisis were purely coincidental. Full Article movie Army of the Dead
dead Deadline for Millennium Point Charitable Trust applications By thebirminghampress.com Published On :: Thu, 26 Nov 2020 00:00:11 +0000 Final call for STEM organisations to apply for grant funding. Full Article Charities Education Science & technology Training Aston Villa Foundation Longwill School for the Deaf Millennium Point Charitable Trust West Midlands Combined Authority
dead Mother pays tribute to dead son By thebirminghampress.com Published On :: Wed, 04 Sep 2013 10:52:54 +0000 Witnesses still sought to fatal incident. Full Article Dudley Most recent