cancer

NASA and ISS National Lab Choose WFIRM for Innovative Cancer Study

How can microgravity help advance cancer research? This is what an upcoming grant-awarded project sponsored by the International Space Station (ISS) Nation











cancer

Canadian collaboration to accelerate development of cancer treatments - NRC and CCAB invest over $1M to advance innovative therapies first discovered at UofT

NRC and CCAB invest over $1M to advance innovative therapies first discovered at UofTToronto, ON – An innovative collaboration between government, industry, and academia aims to accelerate the development of cancer treatments in Canada. The National Research Council of Canada (NRC) and the Toronto-based Centre for the Commercialization of Antibodies and Biologics (CCAB) have put […]




cancer

Toronto’s first peer cancer education program for black women improves awareness and screening

Toronto, ON — Public health researchers created a first-of-its-kind peer education project targeting black women to improve breast and cervical cancer awareness and screening for black women living in Toronto’s Malvern community. “There is a lot of silence in the black community. People think that cancer is not a black issue and many survivors are […]




cancer

Oncology for pharmacists: A person-centred approach to caring for people living with cancer - Leslie Dan Faculty of Pharmacy, in collaboration with Cancer Care Ontario, Launches New Oncology Program for Pharmacists

Leslie Dan Faculty of Pharmacy, in collaboration with Cancer Care Ontario, Launches New Oncology Program for Pharmacists Toronto, ON – The Office of Continuous Professional Development at the University of Toronto’s Leslie Dan Faculty of Pharmacy, in collaboration with Cancer Care Ontario, is introducing the first comprehensive program in the province for pharmacists focused on […]




cancer

New ‘3-in-1’ Antibody Shows Promise in Cancer Treatment




cancer

Alpine Cleaning & Restoration Specialists Bring Joy to Local Girl Fighting Cancer with a new Playset

Alpine Cleaning & Restoration Specialists team up with ROC Solid Foundation to build a backyard playset for Adlee Frampton, a brave three-year-old battling Stage 2 Wilms Tumor. This generous act not only brings joy to Adlee but also highlights the powerful impact of community support and the healing power of play during challenging times.




cancer

A doctor, his cancer journey and a uniquely teachable moment

Bryant Lin has taken his diagnosis of stage IV ‘never-smoker’ lung cancer, which disproportionately affects those of Asian descent, and turned it into a medical school course. He hopes the world takes notes along with the students and Stanford Medicine community.

The post A doctor, his cancer journey and a uniquely teachable moment appeared first on Scope.




cancer

Sequential delivery combats cancer recurrence and drug resistance

Mesoporous silicon nanoparticles co-deliver chemotherapeutic and genetic drugs with a time lag for more effectively countering cancer-cell protection mechanisms against drugs, as well as inhibiting cell growth and metastasis.




cancer

Lightning coach Jon Cooper’s ‘Coop’s Catch’ charity surpasses $1 million to help kids with cancer

Monday morning, Cooper held his seventh annual “Coop’s Catch for Kids” charity fishing tournament, which benefits pediatric cancer research. Cooper’s first tournament in 2016 raised $60,000. This year’s event has brought the grand total to more than $1 million.





cancer

CertainTeed Partners with Susan G. Komen to Battle Breast Cancer

CertainTeed will donate a percentage of its sales from each of its co-branded GlasRoc Sheathing boards to the Susan G. Komen organization from October 2024 to October 2025.




cancer

S-5! Supporting Battle Against Breast Cancer with Donation, Fundraiser

In addition to a $5,000 donation to advance breast cancer care, S-5! is holding a fundraising campaign to benefit two organizations: the Woody and Millie Ingram Guest House and the Careity Foundation.




cancer

Exterior Point Home Remodeling Sponsors Breast Cancer Walk

See why the owner of Exterior Point Home Remodeling in New Jersey got the entire company involved in National Breast Cancer Awareness Month. 




cancer

Heal breast cancer naturally, 7 essential steps to beating breast cancer

Dana Laake and her special guest Dr. Véronique Desaulniers will discuss her book, Heal Breast Cancer Naturally: 7 Essential Steps to Beating Breast Cancer.

The post Heal breast cancer naturally, 7 essential steps to beating breast cancer first appeared on Federal News Network.




cancer

Hidden Epidemic: Silent Oral Infections Cause Most Heart Attacks and Breast Cancers

Dana Laake and her special guest Dr. Thomas Levy will discuss how silent oral infections are a major factor in most heart attacks and breast cancers.

The post Hidden Epidemic: Silent Oral Infections Cause Most Heart Attacks and Breast Cancers first appeared on Federal News Network.




cancer

Pentagon finishes review of Austin’s failure to tell Biden and other leaders about his cancer

The Pentagon has completed its review of Defense Secretary’s Lloyd Austin’s failure last month to quickly notify the president and other senior leaders about his hospitalization for complications from prostate cancer surgery.

The post Pentagon finishes review of Austin’s failure to tell Biden and other leaders about his cancer first appeared on Federal News Network.




cancer

Computer games help children overcome pain from cancer treatment

Computer games help children overcome pain from cancer treatment




cancer

Treatments for Acne and Rosacea Pose Potential Cancer Risk When Improperly Stored

Researchers found that topical treatment products containing benzoyl peroxide can degrade into the carcinogen benzene if improperly transported or stored.




cancer

Rare Hereditary Cancers Diagnosis and Management

Location: Electronic Resource- 




cancer

RNA/DNA and Cancer

Location: Electronic Resource- 




cancer

Breast Cancer Methods and Protocols

Location: Electronic Resource- 




cancer

Bacterial Therapy of Cancer Methods and Protocols

Location: Electronic Resource- 




cancer

A Cure for Cancer

A Cure for Cancer



  • Assyrian Health Network

cancer

CRISPR Immune Cells Not Only Survive, They Thrive After Infusion Into Cancer Patients

CRISPR Immune Cells Not Only Survive, They Thrive After Infusion Into Cancer Patients

In the first-ever (sanctioned) investigational use of multiple edits to the human genome, a study found that cells edited in three specific ways and then removed from patients and brought back into the lab setting were able to kill cancer months after their original manufacturing and infusion.

This is the first U.S. clinical trial to test the gene editing approach in humans, and the publication of this new data today follows on the initial report last year that researchers were able to use CRISPR/Cas9 technology to successfully edit three cancer patients' immune cells. The ongoing study is a cooperative between Tmunity Therapeutics, the Parker Institute for Cancer Immunotherapy, and the University of Pennsylvania. 

Patients on this trial were treated by Edward A. Stadtmauer, MD, section chief of Hematologic Malignancies at Penn, co-lead author on the study. The approach in this study is closely related to CAR T cell therapy, in which patient immune cells are engineered to fight cancer, but it has some key differences. Just like CAR T, researchers in this study began by collecting a patient's T cells from blood. However, instead of arming these cells with a receptor against a protein such as CD19, the team first used CRISPR/Cas9 editing to remove three genes. The first two edits removed a T cell's natural receptors so they can be reprogrammed to express a synthetic T cell receptor, allowing these cells to seek out and destroy tumors. The third edit removed PD-1, a natural checkpoint that sometimes blocks T cells from doing their job. 

Once the three genes are knocked out, a fourth genetic modification was accomplished using a lentivirus to insert the cancer-specific synthetic T cell receptor, which tells the edited T cells to target an antigen called NY-ESO-1. Previously published data show these cells typically survive for less than a week, but this new analysis shows the edited cells used in this study persisted, with the longest follow up at nine months. 

Several months after the infusion, researchers drew more blood and isolated the CRISPR-edited cells for study. When brought back into the lab setting, the cells were still able to kill tumors. 

The CRISPR-edited T cells used in this study are not active on their own like CAR T cells. Instead, they require the cooperation of a molecule known as HLA-A*02:01, which is only expressed in a subset of patients. This means that patients had to be screened ahead of time to make sure they were a match for the approach. Participants who met the requirements received other clinically-indicated therapy as needed while they waited for their cells to be manufactured. Once that process was completed, all three patients received the gene-edited cells in a single infusion after a short course of chemotherapy. Analysis of blood samples revealed that all three participants had the CRISPR-edited T cells take root and thrive in the patients. While none responded to the therapy, there were no treatment-related serious adverse events. 

CRISPR technology has not previously been tested in humans in the U.S. so the research team had to move through a comprehensive and rigorous series of institutional and federal regulatory approval steps, including approval by the National Institutes of Health's Recombinant DNA Research Advisory Committee and review by the U.S. Food and Drug Administration, as well as Penn's institutional review board and institutional biosafety committee. The entire process required more than two years.

 Researchers say these new data will open the door to later stage studies to investigate and extend this approach to a broader field beyond cancer, several of which are already planned at Penn.

sb admin Thu, 02/06/2020 - 14:52
Categories




cancer

'Grief into action.' Philanthropists give historic $150 million donation to City of Hope for pancreatic cancer research

Entrepreneur Emmet Stephenson and his daughter are giving $150 million to City of Hope to fund an award for innovation research in pancreatic cancer. It's the largest single gift the center has received.




cancer

How AI might help researchers make esophageal cancer less deadly

To improve survival for esophageal cancer patients, researchers are using artificial intelligence to improve screening for the disease.




cancer

Data by the Dozen: Consortium Cancer Maps Provide a 3D View of Tumor Evolution

New 3D blueprints that highlight tumor complexity reveal several new discoveries, some of which challenge existing theories of cancer progression.




cancer

Newsbabes join forces for breast cancer

The Newsbabes -- those pink-clad broads of broadcasting -- are back again this year with their annual breast cancer fundraising, this year raising money for the Howard University Cancer Center. The event, in its fifth year, will be taking place June 27 from 7 to 9 p.m. at the Hamilton in downtown D.C. Tickets cost $75. The host committee consists of WJLA's Rebecca Cooper, NBC4's Angie Goff, CNN's Brianna Keilar and more.




cancer

Cancer Research Takes a Leap Thanks to Nobel-Winning MicroRNA Discovery

The Nobel Prize-winning discovery of microRNA has reshaped our understanding of gene regulation. Learn what these tiny molecules mean for cancer research.




cancer

The Childhood Cancer Coalition eases the disease's burden on Inland Northwest families, one kindness at a time

On Meagan Glubrecht's right forearm is an unmistakable tattoo…




cancer

Talas Singer Phil Naro Lost Battle With Tongue Cancer

A statement issued by the rocker's family reveals that the 63-year-old passed away on May 2 night surrounded by his family and closest friends at his home in Rochester.




cancer

Mother’s Day tribute to cancer charity

"Without Cure Leukaemia my daughter would not be here for Mother’s Day."





cancer

Good Hope leading the way internationally with bladder cancer laser treatment

A Good Hope consultant has won international recognition for leading a new treatment study




cancer

Students to host cancer charity event

Think Pink to raise awareness.




cancer

Get fighting fit and help cancer charity

White collar boxing training offered to fundraisers.




cancer

There Is Hope: New Cancer Study Illuminates Bible Truth

A new study published by the American Cancer Society reveals that nearly half of all cancer deaths are attributable to lifestyle factors. Would a return to God’s original health plan make a difference?




cancer

Experto explica por qué la OMS ha declarado al talco como producto “probablemente cancerígeno”

El Dr. Raúl Murillo, director del Centro Javeriano de Oncología, del hospital universitario San Ignacio, detalló la razón por la cual la OMS ha alertado riesgos por cuenta de este producto utilizado en cosméticos




cancer

Banco de sangre del Instituto Nacional de Cancerología en alerta de desabastecimiento

La Dra. Yina Lancheros, coordinadora del Banco de sangre del INC hizo un llamado en 6AM para que la ciudadanía contribuya a la donación de sangre destinada a pacientes oncológicos




cancer

Cancer taught me the hard truth about speaking up for myself

As a little girl, Jennifer Fotheringham was shushed for asking about cancer. As a grown woman, she was dismissed for asking about a mammogram. Now as a cancer survivor, she knows not to be silenced.



  • Radio/White Coat/ Black Art

cancer

This scientist treated her own cancer with viruses she grew in the lab

Virologist Beata Halassy says self-treatment worked and was a positive experience — but researchers warn that it is not something others should try.




cancer

Rene Marsh Demanding Change After Son Dies From Cancer



Blake Vince Payne was only 2 years old.




cancer

Photos & Video: BF&M Breast Cancer Walk

The annual BF&M Breast Cancer Awareness Walk — which serves to help raise funds for the Bermuda Cancer and Health Centre — was held yesterday [Oct 16]. The charity previously noted that “for more than two decades, the BF&M Breast Cancer Awareness Walk has united our community in the fight against this deadly disease and […]